GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1276 - 1300** of **2074** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism
Regulation of pyruvate metabolism	Armadillo repeat-containing protein 8 E3 ubiquitin-protein transferase MAEA E3 ubiquitin-protein transferase RMND5A E3 ubiquitin-protein transferase RMND5B Glucose-induced degradation protein 4 homolog Glucose-induced degradation protein 8 homolog L-lactate dehydrogenase A chain Muskelin NADP-dependent malic enzyme Polyubiquitin-B Polyubiquitin-C Ran-binding protein 9 Serine/threonine-protein kinase Nek1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 26	P00338 P0CG47 P0CG48 P48163 P62979 P62987 Q7L5Y9 Q8IUR7 Q8IVV7 Q96G75 Q96PY6 Q96S59 Q9H7D7 Q9H871 Q9NWU2 Q9UL63	ARMC8 C17orf39 C20orf11 CDW2 EMP GID4 GID8 KIAA1901 LDHA MAEA ME1 MIP2 MKLN1 NEK1 RANBP9 RANBPM RMND5A RMND5B RPS27A TWA1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VID24 WDR26	Homo sapiens (human)
Fructose catabolism	Aldehyde dehydrogenase 1A1 Fructose-bisphosphate aldolase B Glycerate kinase Ketohexokinase Triokinase/FMN cyclase	P00352 P05062 P50053 Q3LXA3 Q8IVS8	ALDB ALDC ALDH1 ALDH1A1 ALDOB DAK GLYCTK HBEBP4 KHK PUMB1 TKFC	Homo sapiens (human)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	6-pyruvoyl tetrahydrobiopterin synthase Calmodulin-1 Dihydrofolate reductase GTP cyclohydrolase 1 feedback regulatory protein GTP cyclohydrolase 1 Heat shock protein HSP 90-alpha Nitric oxide synthase 3 RAC-alpha serine/threonine-protein kinase Sepiapterin reductase cGMP-dependent protein kinase 2	P00374 P07900 P0DP23 P29474 P30047 P30793 P31749 P35270 Q03393 Q13237	AKT1 CALM CALM1 CAM CAM1 DHFR DYT5 GCH GCH1 GCHFR GFRP HSP90A HSP90AA1 HSPC1 HSPCA NOS3 PKB PRKG2 PRKGR2 PTS RAC SPR	Homo sapiens (human)
Phenylalanine metabolism	Dihydropteridine reductase Isoaspartyl peptidase/L-asparaginase Kynurenine--oxoglutarate transaminase 1 L-amino-acid oxidase Phenylalanine-4-hydroxylase Pterin-4-alpha-carbinolamine dehydratase	P00439 P09417 P61457 Q16773 Q7L266 Q96RQ9	ALP ASRGL1 CCBL1 CRASH DCOH DHPR FIG1 IL4I1 KYAT1 PAH PCBD PCBD1 QDPR SDR33C1	Homo sapiens (human)
Defective CP causes aceruloplasminemia (ACERULOP)	Ceruloplasmin Ferroportin	P00450 Q9NP59	CP FPN FPN1 IREG1 SLC11A3 SLC40A1	Homo sapiens (human)
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages)	Ceruloplasmin Ferroportin	P00450 Q9NP59	CP FPN FPN1 IREG1 SLC11A3 SLC40A1	Homo sapiens (human)
Common Pathway of Fibrin Clot Formation	Antithrombin-III CD177 antigen Coagulation factor V Coagulation factor VIII Coagulation factor X Coagulation factor XIII A chain Coagulation factor XIII B chain Endothelial protein C receptor Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Glia-derived nexin Heparin cofactor 2 Myeloblastin Plasma serine protease inhibitor Platelet factor 4 variant Platelet factor 4 Proteinase-activated receptor 1 Prothrombin Thrombomodulin Vitamin K-dependent protein C Vitamin K-dependent protein S	P00451 P00488 P00734 P00742 P01008 P02671 P02675 P02679 P02776 P04070 P05154 P05160 P05546 P07093 P07204 P07225 P10720 P12259 P24158 P25116 Q8N6Q3 Q9UNN8	AT3 CD177 CF2R CXCL4 CXCL4V1 EPCR F10 F13A F13A1 F13B F2 F2R F5 F8 F8C FGA FGB FGG HCF2 MBN NB1 PAR1 PCI PF4 PF4V1 PI7 PLANH3 PN1 PROC PROCI PROCR PROS PROS1 PRTN3 PRV1 SCYB4 SCYB4V1 SERPINA5 SERPINC1 SERPIND1 SERPINE2 THBD THRM TR	Homo sapiens (human)
Intrinsic Pathway of Fibrin Clot Formation	Alpha-2-macroglobulin Antithrombin-III Coagulation factor IX Coagulation factor VIII Coagulation factor X Coagulation factor XI Coagulation factor XII Complement component 1 Q subcomponent-binding protein, mitochondrial Glia-derived nexin Heparin cofactor 2 Kininogen-1 Lysosomal Pro-X carboxypeptidase Plasma kallikrein Plasma protease C1 inhibitor Plasma serine protease inhibitor Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S von Willebrand factor	P00451 P00734 P00740 P00742 P00748 P01008 P01023 P01042 P03951 P03952 P04070 P04275 P05154 P05155 P05546 P07093 P07225 P07359 P13224 P14770 P40197 P42785 Q07021	A2M AT3 BDK C1IN C1NH C1QBP CPAMD5 F10 F11 F12 F2 F8 F8C F8VWF F9 GC1QBP GP1BA GP1BB GP5 GP9 HABP1 HCF2 KLK3 KLKB1 KNG KNG1 PCI PCP PI7 PLANH3 PN1 PRCP PROC PROCI PROS PROS1 SERPINA5 SERPINC1 SERPIND1 SERPINE2 SERPING1 SF2P32 VWF	Homo sapiens (human)
Defective F8 cleavage by thrombin	Coagulation factor VIII Prothrombin von Willebrand factor	P00451 P00734 P04275	F2 F8 F8C F8VWF VWF	Homo sapiens (human)
Defective cofactor function of FVIIIa variant	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Defective factor IX causes thrombophilia	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Defective F9 variant does not activate FX	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Defective F8 binding to von Willebrand factor	Coagulation factor VIII von Willebrand factor	P00451 P04275	F8 F8C F8VWF VWF	Homo sapiens (human)
Defective F8 secretion	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Defective F8 accelerates dissociation of the A2 domain	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Defective F8 binding to the cell membrane	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Argininosuccinate synthase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 Mitochondrial ornithine transporter 2 N-acetylglutamate synthase, mitochondrial NmrA-like family domain-containing protein 1 Ornithine transcarbamylase, mitochondrial	P00480 P00966 P04424 P05089 P31327 P78540 Q8N159 Q9BXI2 Q9HBL8 Q9Y619	ARG1 ARG2 ASL ASS ASS1 CPS1 HSCARG NAGS NMRAL1 ORC1 ORC2 ORNT1 ORNT2 OTC SLC25A15 SLC25A2	Homo sapiens (human)
Purine salvage	AMP deaminase 1 AMP deaminase 2 AMP deaminase 3 Adenine phosphoribosyltransferase Adenosine deaminase-like protein Adenosine deaminase Adenosine kinase Deoxycytidine kinase Deoxyguanosine kinase, mitochondrial GMP reductase 1 GMP reductase 2 Hypoxanthine-guanine phosphoribosyltransferase Purine nucleoside phosphorylase	P00491 P00492 P00813 P07741 P23109 P27707 P36959 P55263 Q01432 Q01433 Q16854 Q6DHV7 Q9P2T1	ADA ADA1 ADAL ADAL1 ADK AMPD1 AMPD2 AMPD3 APRT DCK DGK DGUOK GMPR GMPR1 GMPR2 HPRT HPRT1 NP PNP	Homo sapiens (human)
Glyoxylate metabolism and glycine degradation	2-Hydroxyacid oxidase 1 4-hydroxy-2-oxoglutarate aldolase, mitochondrial Alanine--glyoxylate aminotransferase 2, mitochondrial Alanine--glyoxylate aminotransferase Aspartate aminotransferase, mitochondrial D-amino-acid oxidase D-aspartate oxidase Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial Glycine N-methyltransferase Glyoxylate reductase/hydroxypyruvate reductase Hydroxyproline dehydrogenase Peroxisomal membrane protein 2	P00505 P14920 P21549 P30038 Q14749 Q86XE5 Q99489 Q9BYV1 Q9NR77 Q9UBQ7 Q9UF12 Q9UJM8	AGT1 AGT2 AGXT AGXT2 ALDH4 ALDH4A1 C10orf65 DAMOX DAO DDO DHDPSL GLXR GNMT GOT2 GOX1 GRHPR HAO1 HOGA1 HSPOX1 HYPDH KYAT4 P5CDH PMP22 PRODH2 PXMP2 SPAT	Homo sapiens (human)
Degradation of cysteine and homocysteine	2-aminoethanethiol dioxygenase 3-mercaptopyruvate sulfurtransferase Acidic amino acid decarboxylase GADL1 Aspartate aminotransferase, mitochondrial Cystathionine gamma-lyase Cysteine dioxygenase type 1 Cysteine sulfinic acid decarboxylase Flavin-containing monooxygenase 1 Thioredoxin, mitochondrial Thiosulfate sulfurtransferase	P00505 P25325 P32929 Q01740 Q16762 Q16878 Q6ZQY3 Q96SZ5 Q99757 Q9Y600	ADO C10orf22 CDO1 CSAD CSD CTH FMO1 GADL1 GOT2 KYAT4 MPST TRX2 TST TST2 TXN2	Homo sapiens (human)
Signaling by ERBB2 ECD mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	P00533 P01111 P01112 P01133 P04626 P07900 P19174 P27986 P29353 P42336 Q07889 Q13480 Q16543 Q96RT1	CDC37 CDC37A EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN GAB1 GRB1 HER1 HER2 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL NRAS PIK3CA PIK3R1 PLC1 PLCG1 SHC SHC1 SHCA SOS1	Homo sapiens (human)
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 E3 ubiquitin-protein ligase CBL Epidermal growth factor receptor GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor SHC-transforming protein 1 Son of sevenless homolog 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P00533 P01111 P01112 P01133 P07900 P0CG47 P0CG48 P19174 P22681 P27986 P29353 P42336 P62979 P62987 Q07889 Q13480 Q16543	CBL CBL2 CDC37 CDC37A EGF EGFR ERBB ERBB1 GAB1 GRB1 HER1 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA NRAS PIK3CA PIK3R1 PLC1 PLCG1 RNF55 RPS27A SHC SHC1 SHCA SOS1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Constitutive Signaling by EGFRvIII	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 E3 ubiquitin-protein ligase CBL Epidermal growth factor receptor GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor SHC-transforming protein 1 Son of sevenless homolog 1	P00533 P01111 P01112 P01133 P07900 P19174 P22681 P27986 P29353 P42336 Q07889 Q13480 Q16543	CBL CBL2 CDC37 CDC37A EGF EGFR ERBB ERBB1 GAB1 GRB1 HER1 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA NRAS PIK3CA PIK3R1 PLC1 PLCG1 RNF55 SHC SHC1 SHCA SOS1	Homo sapiens (human)
EGFR Transactivation by Gastrin	Epidermal growth factor receptor GTPase HRas GTPase NRas Proheparin-binding EGF-like growth factor Protein kinase C alpha type Son of sevenless homolog 1 Stromelysin-1	P00533 P01111 P01112 P08254 P17252 Q07889 Q99075	DTR DTS EGFR ERBB ERBB1 HBEGF HEGFL HER1 HRAS HRAS1 MMP3 NRAS PKCA PRKACA PRKCA SOS1 STMY1	Homo sapiens (human)
PLCG1 events in ERBB2 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Pro-epidermal growth factor Receptor tyrosine-protein kinase erbB-2	P00533 P01133 P04626 P19174	EGF EGFR ERBB ERBB1 ERBB2 HER1 HER2 MLN19 NEU NGL PLC1 PLCG1	Homo sapiens (human)

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