GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium channel subfamily K member 16 Potassium channel subfamily K member 17	Q96T54 Q96T55	KCNK16 KCNK17 TALK1 TALK2 TASK4	Homo sapiens (human)
Tandem pore domain halothane-inhibited K+ channel (THIK)	Potassium channel subfamily K member 13	Q9HB14	KCNK13	Homo sapiens (human)
TWIK related potassium channel (TREK)	Potassium channel subfamily K member 10 Potassium channel subfamily K member 2 Potassium channel subfamily K member 4	O95069 P57789 Q9NYG8	KCNK10 KCNK2 KCNK4 TRAAK TREK TREK1 TREK2	Homo sapiens (human)
Potassium transport channels	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 1 Inward rectifier potassium channel 16	P48048 P78508 Q9NPI9	KCNJ1 KCNJ10 KCNJ16 ROMK1	Homo sapiens (human)
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)	Solute carrier family 12 member 6	Q9UHW9	KCC3 SLC12A6	Homo sapiens (human)
Cation-coupled Chloride cotransporters	Solute carrier family 12 member 1 Solute carrier family 12 member 2 Solute carrier family 12 member 3 Solute carrier family 12 member 4 Solute carrier family 12 member 5 Solute carrier family 12 member 6 Solute carrier family 12 member 7	P55011 P55017 Q13621 Q9H2X9 Q9UHW9 Q9UP95 Q9Y666	KCC1 KCC2 KCC3 KCC4 KIAA1176 NCC NKCC1 NKCC2 SLC12A1 SLC12A2 SLC12A3 SLC12A4 SLC12A5 SLC12A6 SLC12A7 TSC	Homo sapiens (human)
Downregulation of ERBB4 signaling	E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase NEDD4 NEDD4-like E3 ubiquitin-protein ligase WWP1 Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P12931 P46934 P62979 P62987 Q96J02 Q9H0M0	ITCH KIAA0093 NEDD4 NEDD4-1 RPF1 RPS27A SRC SRC1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWP1	Homo sapiens (human)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-6	P51812 Q15349 Q15418 Q9UK32	ISPK1 MAPKAPK1A MAPKAPK1B MAPKAPK1C RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 RSK1 RSK2 RSK3 RSK4	Homo sapiens (human)
IRAK4 deficiency (TLR5)	Flagellin Interleukin-1 receptor-associated kinase 4 Myeloid differentiation primary response protein MyD88 Toll-like receptor 10 Toll-like receptor 5	O60602 P04949 Q99836 Q9BXR5 Q9NWZ3	IRAK4 MYD88 TIL3 TLR10 TLR5 flaF fliC hag	Homo sapiens (human)
IRAK2 mediated activation of TAK1 complex	Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43187 O43318 P0CG47 P0CG48 P62979 P62987 Q15750 Q8N5C8 Q9NYJ8 Q9Y4K3	IRAK2 KIAA0733 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
MyD88 dependent cascade initiated on endosome	Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 7 Toll-like receptor 9	O43187 P51617 Q99836 Q9NR96 Q9NWZ3 Q9NYK1 Q9Y4K3	IRAK IRAK1 IRAK2 IRAK4 MYD88 RNF85 TLR7 TLR9 TRAF6	Homo sapiens (human)
Pyrophosphate hydrolysis	Inorganic pyrophosphatase 2, mitochondrial Inorganic pyrophosphatase Phospholysine phosphohistidine inorganic pyrophosphate phosphatase	Q15181 Q9H008 Q9H2U2	IOPPP LHPP PP PPA1 PPA2	Homo sapiens (human)
Defective LFNG causes SCDO3	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4	P46531 Q04721 Q8NES3 Q99466 Q9UM47	INT3 LFNG NOTCH1 NOTCH2 NOTCH3 NOTCH4 TAN1	Homo sapiens (human)
cGMP effects	Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Calcium-activated potassium channel subunit beta-2 Calcium-activated potassium channel subunit beta-3 Calcium-activated potassium channel subunit beta-4 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A Inositol 1,4,5-triphosphate receptor associated 1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-dependent protein kinase 2 cGMP-specific 3',5'-cyclic phosphodiesterase	O00408 O76074 O76083 P54750 Q01064 Q12791 Q13237 Q14643 Q16558 Q86W47 Q9HCR9 Q9NPA1 Q9Y233 Q9Y691 Q9Y6F6	INSP3R1 IRAG IRAG1 ITPR1 JAW1L KCNMA KCNMA1 KCNMB1 KCNMB2 KCNMB3 KCNMB4 KCNMBL MRVI1 PDE10A PDE11A PDE1A PDE1B PDE2A PDE5 PDE5A PDE9A PDES1B PRKG2 PRKGR2 SLO	Homo sapiens (human)
Signaling by Insulin receptor	Insulin receptor Insulin	P01308 P06213	INS INSR	Homo sapiens (human)
NF-kB is activated and signals survival	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Sequestosome-1 TNF receptor-associated factor 6 Transcription factor p65 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 P01138 P08138 P0CG47 P0CG48 P19838 P25963 P51617 P62979 P62987 Q04206 Q13501 Q9Y4K3	IKBA IKBKB IKKB IRAK IRAK1 MAD3 NFKB1 NFKB3 NFKBI NFKBIA NGF NGFB NGFR ORCA OSIL RELA RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Ca activated K+ channels	Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Calcium-activated potassium channel subunit beta-2 Calcium-activated potassium channel subunit beta-3 Calcium-activated potassium channel subunit beta-4 Intermediate conductance calcium-activated potassium channel protein 4 Small conductance calcium-activated potassium channel protein 1 Small conductance calcium-activated potassium channel protein 2 Small conductance calcium-activated potassium channel protein 3	O15554 Q12791 Q16558 Q86W47 Q92952 Q9H2S1 Q9NPA1 Q9UGI6 Q9Y691	IK1 IKCA1 K3 KCA4 KCNMA KCNMA1 KCNMB1 KCNMB2 KCNMB3 KCNMB4 KCNMBL KCNN1 KCNN2 KCNN3 KCNN4 SK SK4 SLO	Homo sapiens (human)
MPS I - Hurler syndrome	Alpha-L-iduronidase	P35475	IDUA	Homo sapiens (human)
MPS II - Hunter syndrome	Iduronate 2-sulfatase	P22304	IDS SIDS	Homo sapiens (human)
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate	Isocitrate dehydrogenase [NADP] cytoplasmic	O75874	IDH1 PICD	Homo sapiens (human)
NFE2L2 regulating TCA cycle genes	Isocitrate dehydrogenase [NADP] cytoplasmic NADP-dependent malic enzyme Nuclear factor erythroid 2-related factor 2	O75874 P48163 Q16236	IDH1 ME1 NFE2L2 NRF2 PICD	Homo sapiens (human)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	O14654 P01344 P05019 P08069 P35568 Q9Y4H2	IBP1 IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Homo sapiens (human)
MPS IX - Natowicz syndrome	Hyaluronidase-1	Q12794	HYAL1 LUCA1	Homo sapiens (human)	G35674CY
Clearance of seratonin	Sodium-dependent serotonin transporter	P31645	HTT SERT SLC6A4	Homo sapiens (human)
MPS IIIA - Sanfilippo syndrome A	N-sulphoglucosamine sulphohydrolase	P51688	HSS SGSH	Homo sapiens (human)

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