GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1726 - 1750** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Assembly and release of respiratory syncytial virus (RSV) virions	Fusion glycoprotein F0 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Matrix protein Nucleoprotein Phosphoprotein Protein M2-1 RNA-directed RNA polymerase L	P03418 P03420 P03421 P04545 P07900 P08238 P0DOE7 P28887	F HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB L M M2-1 N P	Homo sapiens (human)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor IX Coagulation factor VII Coagulation factor X Tissue factor pathway inhibitor Tissue factor	P00740 P00742 P08709 P10646 P13726	F10 F3 F7 F9 LACI TFPI TFPI1	Homo sapiens (human)
Defective cofactor function of FVIIIa variant	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Defective factor IX causes thrombophilia	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Defective F9 variant does not activate FX	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9	Homo sapiens (human)
Defective F9 activation	Coagulation factor IX Coagulation factor XI Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V	P00740 P03951 P07359 P13224 P14770 P40197	F11 F9 GP1BA GP1BB GP5 GP9	Homo sapiens (human)
Defective factor XII causes hereditary angioedema	Coagulation factor XII Plasma kallikrein Prothrombin	P00734 P00748 P03952	F12 F2 KLK3 KLKB1	Homo sapiens (human)
Defective F8 cleavage by thrombin	Coagulation factor VIII Prothrombin von Willebrand factor	P00451 P00734 P04275	F2 F8 F8C F8VWF VWF	Homo sapiens (human)
Platelet Aggregation (Plug Formation)	Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin Thrombopoietin receptor Thrombopoietin von Willebrand factor	P00734 P04275 P07359 P13224 P14770 P40197 P40225 P40238	F2 F8VWF GP1BA GP1BB GP5 GP9 MGDF MPL THPO TPOR VWF	Homo sapiens (human)
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O60825 P16118 P17612 P22612 P22694 P30153 P30154 P62714 P67775 Q14738 Q16875 Q16877	F6PK PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFRX PKACA PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKACA PRKACB PRKACG	Homo sapiens (human)
Defective F8 binding to von Willebrand factor	Coagulation factor VIII von Willebrand factor	P00451 P04275	F8 F8C F8VWF VWF	Homo sapiens (human)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Fructosamine-3-kinase Ketosamine-3-kinase Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2	O60507 O60704 O60725 P00451 Q9H479 Q9HA64	F8 F8C FN3K FN3KRP ICMT PCCMT TPST1 TPST2	Homo sapiens (human)
Defective F8 sulfation at Y1699	Coagulation factor VIII Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2	O60507 O60704 P00451	F8 F8C TPST1 TPST2	Homo sapiens (human)
Defective F8 secretion	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Defective F8 accelerates dissociation of the A2 domain	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Defective F8 binding to the cell membrane	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
GP1b-IX-V activation signalling	14-3-3 protein zeta/delta Filamin-A Phosphatidylinositol 3-kinase regulatory subunit alpha Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V RAF proto-oncogene serine/threonine-protein kinase von Willebrand factor	P04049 P04275 P07359 P13224 P14770 P21333 P27986 P40197 P63104	F8VWF FLN FLN1 FLNA GP1BA GP1BB GP5 GP9 GRB1 PIK3R1 RAF RAF1 VWF YWHAZ	Homo sapiens (human)
Defective binding of VWF variant to GPIb:IX:V	Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V von Willebrand factor	P04275 P07359 P13224 P14770 P40197	F8VWF GP1BA GP1BB GP5 GP9 VWF	Homo sapiens (human)
Enhanced binding of GP1BA variant to VWF multimer:collagen	Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V von Willebrand factor	P04275 P07359 P13224 P14770 P40197	F8VWF GP1BA GP1BB GP5 GP9 VWF	Homo sapiens (human)
Defective VWF binding to collagen type I	von Willebrand factor	P04275	F8VWF VWF	Homo sapiens (human)
Defective gamma-carboxylation of F9	Coagulation factor IX Vitamin K-dependent gamma-carboxylase	P00740 P38435	F9 GC GGCX	Homo sapiens (human)
Defective F9 secretion	Coagulation factor IX	P00740	F9	Homo sapiens (human)
Tyrosine catabolism	4-hydroxyphenylpyruvate dioxygenase Fumarylacetoacetase Homogentisate 1,2-dioxygenase Maleylacetoacetate isomerase Tyrosine aminotransferase	O43708 P16930 P17735 P32754 Q93099	FAH GSTZ1 HGD HGO HPD MAAI PPD TAT	Homo sapiens (human)
Interleukin-2 signaling	Cytokine receptor common subunit gamma Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Protein-tyrosine kinase 2-beta SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase Lck Tyrosine-protein kinase SYK	P01589 P06239 P14784 P23458 P29353 P31785 P42229 P43405 P51692 P52333 P60568 Q14289	FAK2 IL15RB IL2 IL2RA IL2RB IL2RG JAK1 JAK1A JAK1B JAK3 LCK PTK2B PYK2 RAFTK SHC SHC1 SHCA STAT5 STAT5A STAT5B SYK	Homo sapiens (human)
TNFR1-mediated ceramide production	Protein FAN Small ribosomal subunit protein RACK1 Sphingomyelin phosphodiesterase 2 Sphingomyelin phosphodiesterase 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor	O60906 P01375 P19438 P63244 Q92636 Q9NY59	FAN GNB2L1 NSMAF RACK1 SMPD2 SMPD3 TNF TNFA TNFAR TNFR1 TNFRSF1A TNFSF2	Homo sapiens (human)

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