GlyCosmos Portal

Mus musculus (house mouse)

Summary

Taxonomy ID: 10090
PubChem Taxonomy: 10090

Genes (662) Glycans (1270) Glycoproteins (13000) Lectins (276) Pathways (1335)

Displaying entries **1151 - 1175** of **1335** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P51174 Q61425 Q8BH95 Q8BMS1 Q99JY0	Acadl Echs1 Hadh Hadha Hadhb Hadhsc Mschad Schad
Complex I biogenesis	Acyl carrier protein, mitochondrial Arginine-hydroxylase NDUFAF5, mitochondrial Complex I assembly factor ACAD9, mitochondrial Complex I assembly factor TIMMDC1, mitochondrial Complex I assembly factor TMEM126B, mitochondrial Complex I intermediate-associated protein 30, mitochondrial Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Iron-sulfur cluster transfer protein NUBPL NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 Protein arginine methyltransferase NDUFAF7, mitochondrial Transmembrane protein 186	A2AIL4 A2APY7 O09111 O35683 P03888 P03893 P03899 P03911 P03921 P03925 P0DN34 P52503 Q3UIU2 Q59J78 Q7TMF3 Q8BK30 Q8BUY5 Q8JZN5 Q8K3J1 Q91VD9 Q91WD5 Q91YT0 Q99LC3 Q99LY9 Q9CPP6 Q9CPU2 Q9CQ54 Q9CQ75 Q9CQ91 Q9CQC7 Q9CQH3 Q9CQJ8 Q9CQY9 Q9CQZ5 Q9CQZ6 Q9CR21 Q9CR61 Q9CR76 Q9CWD8 Q9CWG8 Q9CWX2 Q9CXZ1 Q9D1H6 Q9D1R1 Q9D6J5 Q9D6J6 Q9D8B4 Q9DC69 Q9DC70 Q9DCJ5 Q9DCS9 Q9DCT2 Q9ERS2 Q9JKL4 Q9QZH6 Q9Z1P6	Acad9 Cia30 Ecsit Gm137 Grim19 Hrpap20 Ip13 Mtnd1 Mtnd4 Mtnd5 Mtnd6 Nd1 Nd2 Nd3 Nd4 Nd5 Nd6 Ndufa1 Ndufa10 Ndufa11 Ndufa12 Ndufa12l Ndufa13 Ndufa2 Ndufa3 Ndufa5 Ndufa6 Ndufa7 Ndufa8 Ndufa9 Ndufab1 Ndufaf1 Ndufaf2 Ndufaf3 Ndufaf4 Ndufaf5 Ndufaf6 Ndufaf7 Ndufb1 Ndufb10 Ndufb11 Ndufb2 Ndufb3 Ndufb4 Ndufb5 Ndufb6 Ndufb7 Ndufb8 Ndufb9 Ndufc1 Ndufc2 Ndufs1 Ndufs2 Ndufs3 Ndufs4 Ndufs5 Ndufs6 Ndufs7 Ndufs8 Ndufv1 Ndufv2 Ndufv3 Np15 Nubpl Sitpec Timmdc1 Tmem126b Tmem186 mt-Nd1 mt-Nd2 mt-Nd3 mt-Nd4 mt-Nd5 mt-Nd6
Branched-chain amino acid catabolism	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxyisobutyrate dehydrogenase, mitochondrial 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Acetyl-CoA acetyltransferase, mitochondrial Branched-chain alpha-ketoacid dehydrogenase kinase Branched-chain-amino-acid aminotransferase, cytosolic Branched-chain-amino-acid aminotransferase, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Isobutyryl-CoA dehydrogenase, mitochondrial Isovaleryl-CoA dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Methylglutaconyl-CoA hydratase, mitochondrial Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial Protein phosphatase Mn(2+)-dependent 1K Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	O08749 O08756 O35855 O55028 P24288 P50136 P53395 Q3ULD5 Q6P3A8 Q8BH95 Q8BXN7 Q8QZS1 Q8QZT1 Q99L13 Q99MR8 Q9D7B6 Q9DBL1 Q9EQ20 Q9JHI5 Q9JLZ3	Acad8 Acadsb Acat1 Aldh6a1 Auh Bcat1 Bcat2 Bcatm Bckdha Bckdhb Bckdk Dbt Dld Eca39 Eca40 Echs1 Erab Hadh2 Hibadh Hibch Hsd17b10 Ivd Mcca Mccc1 Mccc2 Pp2cm Ppm1k
Fatty acyl-CoA biosynthesis	(3R)-3-hydroxyacyl-CoA dehydrogenase 3-oxoacyl-[acyl-carrier-protein] reductase ATP-citrate synthase ATPase MORC2A Acetyl-CoA carboxylase 1 Fatty acid synthase Long-chain fatty acid transport protein 2 Lysosomal thioesterase PPT2 Palmitoyl-protein thioesterase 1 Stearoyl-CoA desaturase 2	O35448 O35488 O88531 P13011 P19096 P50171 Q5SWU9 Q69ZX6 Q91V92 Q91VT4	Acac Acaca Acly Acsvl1 Cbr4 Cln1 Facvl1 Fasn Fatp2 Gm738 H2-Ke6 Hke6 Hsd17b8 Kiaa0852 Morc2a Ppt Ppt1 Ppt2 Scd2 Slc27a2 Vlacs Vlcs Zcwcc1
Biotin transport and metabolism	Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 Biotin--protein ligase Biotinidase Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial PDZ domain-containing protein 11 Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate carboxylase, mitochondrial Sodium-dependent multivitamin transporter	E9Q4Z2 Q05920 Q3ULD5 Q5SWU9 Q5U4D8 Q8CIF4 Q91ZA3 Q920N2 Q99MN9 Q99MR8 Q9CZG9	Acac Acaca Acacb Acc2 Accb Btd Gm738 Hlcs Mcca Mccc1 Mccc2 Pc Pcca Pccb Pcx Pdzd11 Pdzk11 Slc5a6
Mitochondrial Fatty Acid Beta-Oxidation	3-ketoacyl-CoA thiolase, mitochondrial Acetyl-coenzyme A thioesterase Acyl carrier protein, mitochondrial Acyl-CoA dehydrogenase family member 10 Acyl-CoA dehydrogenase family member 11 Acyl-CoA-binding domain-containing protein 6 Acyl-CoA-binding domain-containing protein 7 Acyl-CoA-binding protein Acyl-coenzyme A thioesterase 11 Acyl-coenzyme A thioesterase 13 Acyl-coenzyme A thioesterase 1 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 3 Acyl-coenzyme A thioesterase 5 Acyl-coenzyme A thioesterase 9, mitochondrial Acyl-coenzyme A thioesterase THEM4 Acyl-coenzyme A thioesterase THEM5 Cytosolic acyl coenzyme A thioester hydrolase Malonyl-CoA-acyl carrier protein transacylase, mitochondrial Medium-chain acyl-CoA ligase ACSF2, mitochondrial Phosphatidylcholine transfer protein	O55137 P31786 P53808 Q3UUI3 Q6Q2Z6 Q80XL6 Q8BWT1 Q8K370 Q8R3F5 Q8VCW8 Q8VHQ9 Q91V12 Q9CQJ0 Q9CQR4 Q9CR21 Q9D061 Q9D258 Q9DBK0 Q9QYR7 Q9QYR9 Q9R0X4	Acaa2 Acad10 Acad11 Acate2 Acbd6 Acbd7 Acot1 Acot11 Acot12 Acot13 Acot15 Acot2 Acot3 Acot5 Acot7 Acot9 Acsf2 Bach Bfit Cach Cach1 Cte1 Ctmp Dbi Mcat Mt Mte1 Ndufab1 Pctp Pte1a Pte2 Pte2a Stard2 Thea Them2 Them4 Them5
Peroxisomal protein import	2-Hydroxyacid oxidase 1 2-Hydroxyacid oxidase 2 2-hydroxyacyl-CoA lyase 1 3-ketoacyl-CoA thiolase B, peroxisomal AN1-type zinc finger protein 6 Acyl-coenzyme A diphosphatase NUDT19 Acyl-coenzyme A thioesterase 1 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 3 Acyl-coenzyme A thioesterase 5 Acyl-coenzyme A thioesterase 8 Alanine--glyoxylate aminotransferase Alkyldihydroxyacetonephosphate synthase, peroxisomal Alpha-methylacyl-CoA racemase Bifunctional epoxide hydrolase 2 Bile acid-CoA Carnitine O-acetyltransferase Catalase D-amino-acid oxidase D-aspartate oxidase Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Enoyl-CoA delta isomerase 2 Glutathione S-transferase kappa 1 Hydroxymethylglutaryl-CoA lyase, mitochondrial Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] cytoplasmic Lon protease homolog 2, peroxisomal Long-chain fatty acid transport protein 2 Malonyl-CoA decarboxylase, mitochondrial Nitric oxide synthase, inducible Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal ATPase PEX1 Peroxisomal ATPase PEX6 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal bifunctional enzyme Peroxisomal carnitine O-octanoyltransferase Peroxisomal coenzyme A diphosphatase NUDT7 Peroxisomal leader peptide-processing protease Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal multifunctional enzyme type 2 Peroxisomal sarcosine oxidase Peroxisomal succinyl-coenzyme A thioesterase Peroxisomal targeting signal 2 receptor Peroxisomal trans-2-enoyl-CoA reductase Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Phytanoyl-CoA dioxygenase, peroxisomal Polyubiquitin-B Polyubiquitin-C Protein Mpv17 Sterol carrier protein 2 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	B1AUE5 O09174 O35386 O35423 O35459 O35488 O55137 O88844 P0CG49 P0CG50 P11930 P18894 P19258 P24270 P29477 P32020 P34914 P38060 P47934 P51660 P55098 P58137 P61079 P61080 P62838 P62983 P62984 P70398 P97865 P98192 Q5BL07 Q6Q2Z6 Q8BGI5 Q8BWN8 Q8C0I1 Q8C0L6 Q8VC48 Q8VCH0 Q91X34 Q922Z0 Q99J39 Q99LB2 Q99LC9 Q99MZ7 Q99P30 Q9D0K1 Q9D826 Q9DBA6 Q9DBM2 Q9DBN5 Q9DC50 Q9DCH6 Q9DCM2 Q9EPL9 Q9JHR7 Q9NYQ2 Q9QXD1 Q9QXE0 Q9QYR7 Q9QYR9 Q9R0A0 Q9R0H0 Q9WU19 Q9WUR2 Q9WV68	Acaa1 Acaa1b Acot1 Acot2 Acot3 Acot4 Acot5 Acot8 Acox Acox1 Acox2 Acox3 Acsvl1 Agps Agxt Agxt1 Amacr Awp1 Baat Cas-1 Cas1 Cat Cot Crat Crot Cte1 D14Ucla2 D7Rp2e Dao Dao1 Ddo Decr2 Dhapat Dhrs4 Ech1 Eci2 Edh17b4 Ehhadh Eph2 Ephx2 Facvl1 Fafl Fam Fatp2 Gnpat Gstk1 Hacl1 Hao1 Hao2 Hao3 Haox2 Hmgcl Hpcl Hsd17b4 Ide Idh1 Inosl L-pbe Ln1 Lnap1 Lonp2 Macr1 Mlycd Mpv17 Mte1 Nos2 Nudt19 Nudt7 Paf1 Pahx Pao Paox Pdcr Peci Pecr Pex1 Pex10 Pex12 Pex13 Pex14 Pex2 Pex26 Pex6 Pex7 Phyh Phyh2 Pipox Pmp35 Pso Pte1 Pte1a Pte1b Pte2 Pte2a Pte2b Pxmp3 Rps27a Scp-2 Scp2 Slc27a2 Tysnd1 Uba52 Uba80 Ubb Ubc Ubc4 Ubcep1 Ubcep2 Ubch4 Ubch5b Ube2d1 Ube2d2 Ube2d2a Ube2d3 Usp9x Vlacs Vlcs Za20d3 Zfand6
G2/M DNA damage checkpoint	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein homolog Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Cellular tumor antigen p53 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein homolog Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/G Histone H2B type 1-F/J/L Histone H2B type 1-H Histone H2B type 1-K Histone H2B type 1-M Histone H2B type 1-P Histone H2B type 2-E Histone H2B type 3-B Histone H3 Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2	A0A8I4SYN6 O09053 O35280 O70157 O70445 O88700 P02340 P10853 P10854 P27661 P46737 P48754 P61089 P62806 P70388 P70399 P70696 Q3UI43 Q3UPE3 Q4U2R1 Q5PSV9 Q5SXJ3 Q5U5Q9 Q61216 Q62193 Q62388 Q64475 Q64478 Q64524 Q6NXW6 Q6WBX7 Q6ZQF0 Q6ZQJ5 Q6ZWY9 Q80XJ2 Q80YR6 Q8BMG1 Q8BPZ8 Q8BQY8 Q8BVE8 Q8CGP0 Q8CGP1 Q8CGP2 Q8CHK4 Q8K3A4 Q8K3W0 Q8R323 Q8VC56 Q8VEE4 Q99J62 Q9CQ71 Q9D0F6 Q9D2M8 Q9D4G9 Q9JKK8 Q9JM05 Q9QWZ1 Q9QZ11 Q9R207 Q9WUK4 Q9Z0F6 Q9Z265	Abra1 Abraxas1 Atm Atr Atrip Babam1 Babam2 Bach1 Bard1 Blm Blu Brca1 Brcc3 Brcc36 Bre Brip1 C6.1a Ccdc98 Chek1 Chek2 Chk1 Chk2 Ctip Dna2 Dna2l Exo1 Fam175a Fancj Gm929 H2a.x H2afx H2ax H2b-f H2b-j H2b-l H2b-n H2bc1 H2bc11 H2bc12 H2bc13 H2bc14 H2bc15 H2bc21 H2bc26 H2bc26-ps H2bc3 H2bc4 H2bc6 H2bc7 H2bc8 H2bc9 H2bu1 H2bu1-ps H3f4 H4-12 H4-53 H4c1 H4c11 H4c12 H4c14 H4c16 H4c2 H4c3 H4c4 H4c6 H4c8 H4c9 H4f16 Herc2 Hist1h2ba Hist1h2bb Hist1h2bc Hist1h2be Hist1h2bf Hist1h2bg Hist1h2bh Hist1h2bj Hist1h2bk Hist1h2bl Hist1h2bm Hist1h2bn Hist1h2bp Hist1h4a Hist1h4b Hist1h4c Hist1h4d Hist1h4f Hist1h4h Hist1h4i Hist1h4j Hist1h4k Hist1h4m Hist2h2be Hist2h4 Hist2h4a Hist3h2bb Hist3h2bb-ps Hist4h4 Hist5-2ax Htatip Hus1 Jdf2 Kat5 Kiaa0083 Kiaa0170 Kiaa0259 Kiaa0393 Kiaa1090 Kiaa4069 Mdc1 Merit40 Mms2 Mre11 Mre11a Nba1 Nbn Nbs1 Nsd2 P53 Pias4 Piasg Rad1 Rad17 Rad50 Rad53 Rad9 Rad9a Rad9b Rap80 Rbbp8 Rec1 Rfc2 Rfc3 Rfc4 Rfc5 Rhno1 Rip110 Rjs Rmi1 Rmi2 Rnf168 Rnf8 Rpa1 Rpa2 Rpa3 Rpa34 Rxrip110 Th2b Tip60 Top3 Top3a Topbp1 Tp53 Tp53bp1 Trp53 Trp53bp1 Ube2n Ube2v2 Uev2 Uimc1 Whsc1 Wrn
Processing of DNA double-strand break ends	ATR-interacting protein BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein homolog Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 Claspin Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF4 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 Fanconi anemia group J protein homolog Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/G Histone H2B type 1-F/J/L Histone H2B type 1-H Histone H2B type 1-K Histone H2B type 1-M Histone H2B type 1-P Histone H2B type 2-E Histone H2B type 3-B Histone H3 Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 NAD-dependent protein deacylase sirtuin-6 Nibrin Polyubiquitin-B Polyubiquitin-C Protein timeless homolog RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Serine/threonine-protein phosphatase 4 catalytic subunit Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2 TIMELESS-interacting protein TP53-binding protein 1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I4SYN6 O09053 O35280 O70157 O70445 O88700 P0CG49 P0CG50 P10853 P10854 P27661 P46737 P48754 P51943 P59941 P61089 P61957 P62806 P62983 P62984 P63280 P70388 P70399 P70696 P97377 P97470 Q0VGB7 Q3UI43 Q3UPE3 Q4U2R1 Q5PSV9 Q5SXJ3 Q5U5Q9 Q61216 Q61456 Q62193 Q62388 Q64475 Q64478 Q64524 Q6NXW6 Q6WBX7 Q6ZQF0 Q6ZQJ5 Q6ZWY9 Q80XJ2 Q80YR6 Q80YR7 Q8BMG1 Q8BPZ8 Q8BQY8 Q8BVE8 Q8CGP0 Q8CGP1 Q8CGP2 Q8CHK4 Q8K3A4 Q8K3W0 Q8R323 Q8VC56 Q8VEE4 Q91WA1 Q99J62 Q9CQ71 Q9D0F6 Q9D2M8 Q9D4G9 Q9JKK8 Q9JM05 Q9QWZ1 Q9QZ11 Q9QZS2 Q9R1X4 Q9R207 Q9WUK4 Q9Z0F6	Abra1 Abraxas1 Atm Atr Atrip Babam1 Babam2 Bach1 Bard1 Blm Blu Brca1 Brcc3 Brcc36 Bre Brip1 C6.1a Ccdc98 Ccna Ccna1 Ccna2 Cdk2 Cdkn2 Chek1 Chk1 Clspn Ctip Cyca Cyca2 Dna2 Dna2l Exo1 Fam175a Fancj Gm929 H2a.x H2afx H2ax H2b-f H2b-j H2b-l H2b-n H2bc1 H2bc11 H2bc12 H2bc13 H2bc14 H2bc15 H2bc21 H2bc26 H2bc26-ps H2bc3 H2bc4 H2bc6 H2bc7 H2bc8 H2bc9 H2bu1 H2bu1-ps H3f4 H4-12 H4-53 H4c1 H4c11 H4c12 H4c14 H4c16 H4c2 H4c3 H4c4 H4c6 H4c8 H4c9 H4f16 Herc2 Hist1h2ba Hist1h2bb Hist1h2bc Hist1h2be Hist1h2bf Hist1h2bg Hist1h2bh Hist1h2bj Hist1h2bk Hist1h2bl Hist1h2bm Hist1h2bn Hist1h2bp Hist1h4a Hist1h4b Hist1h4c Hist1h4d Hist1h4f Hist1h4h Hist1h4i Hist1h4j Hist1h4k Hist1h4m Hist2h2be Hist2h4 Hist2h4a Hist3h2bb Hist3h2bb-ps Hist4h4 Hist5-2ax Htatip Hus1 Jdf2 Kat5 Kiaa0083 Kiaa0170 Kiaa0259 Kiaa0393 Kiaa1090 Kiaa4069 Mdc1 Merit40 Mms2 Mre11 Mre11a Nba1 Nbn Nbs1 Nsd2 Pias4 Piasg Ppp4 Ppp4c Ppp4r2 Ppx Rad1 Rad17 Rad50 Rad9 Rad9a Rad9b Rap80 Rbbp8 Rec1 Rfc2 Rfc3 Rfc4 Rfc5 Rhno1 Rip110 Rjs Rmi1 Rmi2 Rnf168 Rnf4 Rnf8 Rpa1 Rpa2 Rpa3 Rpa34 Rps27a Rxrip110 Sir2l6 Sirt6 Smt3b Smt3h2 Sumo2 Th2b Tim1 Timeless Timeless1 Tip60 Tipin Top3 Top3a Topbp1 Tp53bp1 Trp53bp1 Uba52 Uba80 Ubb Ubc Ubc9 Ubce2i Ubce9 Ubcep1 Ubcep2 Ube2i Ube2n Ube2v2 Uev2 Uimc1 Whsc1 Wrn
Nonhomologous End-Joining (NHEJ)	BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein homolog DNA ligase 4 DNA polymerase lambda DNA repair protein RAD50 DNA repair protein XRCC4 DNA-dependent protein kinase catalytic subunit DNA-directed DNA/RNA polymerase mu Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/G Histone H2B type 1-F/J/L Histone H2B type 1-H Histone H2B type 1-K Histone H2B type 1-M Histone H2B type 1-P Histone H2B type 2-E Histone H2B type 3-B Histone H3 Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin Non-homologous end-joining factor 1 PAX-interacting protein 1 Protein artemis Serine-protein kinase ATM TP53-binding protein 1 Telomere-associated protein RIF1 Tyrosyl-DNA phosphodiesterase 1 Tyrosyl-DNA phosphodiesterase 2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	A0A8I4SYN6 O70445 P10853 P10854 P23475 P27641 P27661 P46737 P48754 P61089 P62806 P70388 P70399 P70696 P97313 Q3KNJ2 Q3UI43 Q4U2R1 Q5PSV9 Q5U5Q9 Q61216 Q62388 Q64475 Q64478 Q64524 Q6NZQ4 Q6PR54 Q6ZWY9 Q80XJ2 Q8BJ37 Q8BPZ8 Q8BTF7 Q8BVE8 Q8CGP0 Q8CGP1 Q8CGP2 Q8CHK4 Q8K3W0 Q8K4J0 Q8VC56 Q924T3 Q9D2M8 Q9JIW4 Q9JJX7 Q9JM05 Q9QXE2 Q9R207	Abra1 Abraxas1 Art Atm Babam1 Babam2 Bard1 Blu Brca1 Brcc3 Brcc36 Bre C6.1a Ccdc98 Dclre1c Fam175a G22p1 G22p2 H2a.x H2afx H2ax H2b-f H2b-j H2b-l H2b-n H2bc1 H2bc11 H2bc12 H2bc13 H2bc14 H2bc15 H2bc21 H2bc26 H2bc26-ps H2bc3 H2bc4 H2bc6 H2bc7 H2bc8 H2bc9 H2bu1 H2bu1-ps H3f4 H4-12 H4-53 H4c1 H4c11 H4c12 H4c14 H4c16 H4c2 H4c3 H4c4 H4c6 H4c8 H4c9 H4f16 Herc2 Hist1h2ba Hist1h2bb Hist1h2bc Hist1h2be Hist1h2bf Hist1h2bg Hist1h2bh Hist1h2bj Hist1h2bk Hist1h2bl Hist1h2bm Hist1h2bn Hist1h2bp Hist1h4a Hist1h4b Hist1h4c Hist1h4d Hist1h4f Hist1h4h Hist1h4i Hist1h4j Hist1h4k Hist1h4m Hist2h2be Hist2h4 Hist2h4a Hist3h2bb Hist3h2bb-ps Hist4h4 Hist5-2ax Htatip Jdf2 Kat5 Kiaa0170 Kiaa0393 Kiaa1090 Ku70 Lig4 Mdc1 Merit40 Mms2 Mre11 Mre11a Nba1 Nbn Nbs1 Nhej1 Nsd2 Paxip1 Pias4 Piasg Polk Poll Polm Prkdc Ptip Rad50 Rap80 Rif1 Rip110 Rjs Rnf168 Rnf8 Rxrip110 Snm1l Tdp1 Tdp2 Th2b Tip60 Tp53bp1 Trp53bp1 Ttrap Ube2n Ube2v2 Uev2 Uimc1 Whsc1 Xlf Xrcc4 Xrcc5 Xrcc6 Xrcc7 polmu
Metalloprotease DUBs	26S proteasome non-ATPase regulatory subunit 14 AMSH-like protease BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 BRISC complex subunit Abraxas 2 Breast cancer type 1 susceptibility protein homolog Deubiquitinase MYSM1 Histone H2A type 1-B Histone H2A type 1-C Histone H2A type 1-E Histone H2A type 1-F Histone H2A type 1-G Histone H2A type 1-H Histone H2A type 1-I Histone H2A type 1-K Histone H2A type 1-N Histone H2A type 1-O Histone H2A type 1-P Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Histone H2A.J Histone H2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Lys-63-specific deubiquitinase BRCC36 NACHT, LRR and PYD domains-containing protein 3 Polyubiquitin-B Polyubiquitin-C STAM-binding protein Signal transducing adapter molecule 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	B2RWS6 C0HKE1 C0HKE2 C0HKE4 C0HKE5 C0HKE6 C0HKE7 C0HKE8 C0HKE9 O35593 O70445 P0CG49 P0CG50 P46737 P48754 P62983 P62984 P70297 Q3TCJ1 Q3UI43 Q5U5Q9 Q64522 Q64523 Q69Z66 Q6GSS7 Q76N33 Q8BFU2 Q8BPZ8 Q8CGP4 Q8CGP5 Q8CGP6 Q8CGP7 Q8K3W0 Q8R1M2 Q8R4B8 Q9CQ26 Q9JHD1	Abra1 Abraxas1 Abraxas2 Abro1 Amsh Amshlp Babam1 Babam2 Bard1 Brca1 Brcc3 Brcc36 Bre C6.1a Ccdc98 Cias1 Ep300 Fam175a Fam175b H2ac1 H2ac11 H2ac12 H2ac13 H2ac15 H2ac20 H2ac21 H2ac25 H2ac4 H2ac6 H2ac8 H2aj H2aw Hist1h2aa Hist1h2ab Hist1h2ac Hist1h2ae Hist1h2af Hist1h2ag Hist1h2ah Hist1h2ai Hist1h2ak Hist1h2an Hist1h2ao Hist1h2ap Hist2h2aa1 Hist2h2aa2 Hist2h2ab Hist2h2ac Hist3h2a Kat2b Kiaa0157 Kiaa1915 Merit40 Mmig1 Mysm1 Nalp3 Nba1 Nlrp3 P300 Pad1 Pcaf Psmd14 Pypaf1 Rap80 Rip110 Rps27a Rxrip110 Stam Stam1 Stambp Stambpl1 Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2 Uimc1
CDC42 GTPase cycle	Active breakpoint cluster region-related protein Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ArhGAP9 Breakpoint cluster region protein Caveolin-1 Cell division control protein 42 homolog DEP domain-containing protein 1B Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 11 Dedicator of cytokinesis protein 6 Dedicator of cytokinesis protein 7 Dedicator of cytokinesis protein 8 Dedicator of cytokinesis protein 9 Delta(14)-sterol reductase LBR Differentially expressed in FDCP 6 Dynamin-binding protein Ephexin-1 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 GEM-interacting protein Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kinectin Mcf.2 transforming sequence N-chimaerin Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Pleckstrin homology domain containing, family G (with RhoGef domain) member 1 Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 3 Protein ECT2 Protein FAM13B Rac GTPase-activating protein 1 RalA-binding protein 1 Ras-specific guanine nucleotide-releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GDP-dissociation inhibitor 3 Rho GTPase activating protein 4 Rho GTPase-activating protein 10 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 20 Rho GTPase-activating protein 21 Rho GTPase-activating protein 22 Rho GTPase-activating protein 24 Rho GTPase-activating protein 26 Rho GTPase-activating protein 27 Rho GTPase-activating protein 29 Rho GTPase-activating protein 30 Rho GTPase-activating protein 31 Rho GTPase-activating protein 32 Rho GTPase-activating protein 33 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 40 Rho GTPase-activating protein 42 Rho GTPase-activating protein 44 Rho GTPase-activating protein 45 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor (GEF) 11 Rho guanine nucleotide exchange factor (GEF) 26 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 SLIT-ROBO Rho GTPase-activating protein 1 SLIT-ROBO Rho GTPase-activating protein 2 SLIT-ROBO Rho GTPase-activating protein 3 Spermatogenesis-associated protein 13 StAR-related lipid transfer protein 13 StAR-related lipid transfer protein 8 Synaptobrevin homolog YKT6 T-cell activation Rho GTPase-activating protein Triple functional domain protein Unconventional myosin-IXb	A0A5F8MPP0 A2AB59 A2AF47 A6X8Z5 B1AUY3 B2RQE8 B2RWW0 D3YYY8 E9Q6X9 E9Q7D5 F8VPU2 O08908 O88842 P26450 P27601 P49817 P52734 P59281 P60766 P70392 P97393 Q07139 Q0KL02 Q1HDU4 Q3LAC4 Q3TBD2 Q3U5C8 Q3U9G9 Q3UIA2 Q3UTH8 Q4LDD4 Q4VAC9 Q5DU57 Q5FWH6 Q5FWK3 Q5SSL4 Q5SSM3 Q60610 Q60992 Q61595 Q61599 Q62160 Q62172 Q64096 Q640N3 Q68FM7 Q69ZK0 Q6DFV3 Q6IFT4 Q6KAU7 Q6PAJ1 Q6PGG2 Q6TXD4 Q6Y5D8 Q6ZQ82 Q80YF9 Q811P8 Q812A2 Q8BH88 Q8BIK4 Q8BL80 Q8BLE2 Q8BWA8 Q8BY35 Q8BZ05 Q8BZN6 Q8C033 Q8C147 Q8C2K1 Q8C4V1 Q8CGF1 Q8CHT1 Q8K031 Q8K2H3 Q8K4I3 Q8R1A4 Q8R4H2 Q8R5G7 Q8VDR9 Q91V57 Q91YM2 Q91Z67 Q91Z69 Q91ZT5 Q923Q2 Q99J31 Q99PT1 Q9CQW1 Q9CWR0 Q9DBZ9 Q9QY06 Q9R0C8 Q9R0Z9 Q9WVM1 Q9Z0R4	Abr Arap1 Arap2 Arap3 Arhgap1 Arhgap10 Arhgap13 Arhgap14 Arhgap17 Arhgap2 Arhgap20 Arhgap21 Arhgap22 Arhgap24 Arhgap26 Arhgap27 Arhgap29 Arhgap30 Arhgap31 Arhgap32 Arhgap33 Arhgap35 Arhgap39 Arhgap4 Arhgap40 Arhgap42 Arhgap44 Arhgap45 Arhgap5 Arhgap7 Arhgap9 Arhgdia Arhgdib Arhgdig Arhgef10 Arhgef11 Arhgef12 Arhgef15 Arhgef16 Arhgef19 Arhgef25 Arhgef26 Arhgef5 Arhgef6 Arhgef9 Bcr C87222 Camgap1 Cav Cav1 Cdc42 Cdgap Centd1 Centd2 Centd3 Chn1 D10Ertd610e D14Wsu89e D15Wsu169e Dbs Def6 Depdc1b Depdc2 Dlc1 Dnmbp Dock10 Dock11 Dock6 Dock7 Dock8 Dock9 Drag1 Ect2 Ese1 Fam13b Fam13b1 Farp1 Fbp27 Fgd1 Fgd2 Fgd3 Fgd4 Fnbp2 Gdi1 Gdi5 Gdid4 Geft Gm148 Gm430 Gmip Gna-13 Gna13 Graf3 Grf2 Grit Grlf1 Hmha1 Ibp Itsn Itsn1 Kiaa0189 Kiaa0294 Kiaa0382 Kiaa0411 Kiaa0424 Kiaa0580 Kiaa0599 Kiaa0621 Kiaa0694 Kiaa0712 Kiaa0782 Kiaa0915 Kiaa1010 Kiaa1058 Kiaa1204 Kiaa1391 Kiaa1395 Kiaa1415 Kiaa1424 Kiaa1688 Kiaa1722 Kiaa1771 Kiaa3017 Kiaa4097 Ktn1 Larg Lbr Mcf2 Mcf2l Mgcracgap Mnlt Myo9b Myr5 Ngef Ophn1 P190A Pik3r1 Pik3r2 Plekhg1 Plekhg2 Plekhg3 Prex1 Prex2 Racgap1 Ralbp1 Rasgrf2 Rhogap5 Rich2 Rics Rip1 Slat Snx26 Spata13 Srgap1 Srgap2 Srgap3 Stard12 Stard13 Stard8 Syde1 Tagap Tcgap Tiam-1 Tiam1 Trio Tuba Vav2 Vav3 Wgef Ykt6 Ziz1 Ziz2 Ziz3 mKIAA4037 p190ARHOGAP
NRAGE signals death through JNK	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Bcl-2-like protein 11 Bcl2-associated agonist of cell death Ephexin-1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kalirin Mcf.2 transforming sequence Mitogen-activated protein kinase 8 Neuroepithelial cell-transforming gene 1 protein Obscurin Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 5 Protein ECT2 Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor (GEF) 11 Rho guanine nucleotide exchange factor (GEF) 26 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 18 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 Rho guanine nucleotide exchange factor TIAM2 Son of sevenless homolog 1 Son of sevenless homolog 2 Triple functional domain protein	A1IGU4 A2AAJ9 A2AWP8 A2CG49 D3YYY8 E9Q394 E9Q7D5 O54918 O88842 P27601 P27870 P52734 P63001 P70392 Q02384 Q07139 Q0KL02 Q3U5C8 Q3UTH8 Q5FWH6 Q5SSL4 Q60610 Q60875 Q60992 Q61210 Q61337 Q62245 Q64096 Q66JY6 Q66T02 Q68FM7 Q69ZK0 Q6KAU7 Q6P9R4 Q6ZPF3 Q80U35 Q80VK6 Q8BLE2 Q8BW86 Q8BWA8 Q8BY35 Q8C033 Q8CHT1 Q8K4I3 Q8R4H2 Q91X46 Q91Y86 Q91ZT5 Q9CWR0 Q9ES28 Q9R0C8 Q9Z0R4 Q9Z206	Abr Akap13 Arhgef1 Arhgef10 Arhgef10l Arhgef11 Arhgef12 Arhgef15 Arhgef16 Arhgef17 Arhgef18 Arhgef19 Arhgef2 Arhgef25 Arhgef26 Arhgef3 Arhgef33 Arhgef37 Arhgef38 Arhgef39 Arhgef5 Arhgef6 Arhgef7 Arhgef8 Arhgef9 Bad Bbc6 Bcl2l11 Bim Brx D10Ertd610e Dbs Ect2 Ese1 Fgd1 Fgd2 Fgd3 Fgd4 Geft Gm878 Gm941 Gna-13 Gna13 Grf2 Itsn Itsn1 Jnk1 Kalrn Kiaa0142 Kiaa0294 Kiaa0337 Kiaa0382 Kiaa0424 Kiaa0521 Kiaa0651 Kiaa0720 Kiaa0915 Kiaa1415 Kiaa1626 Kiaa2016 Larg Lbcl1 Lbcl2 Lfc Lsc Mapk8 Mcf2 Mcf2l Net1 Ngef Obscn Pak3bp Plekhg2 Plekhg5 Prex1 Prkm8 Rac1 Rasgrf2 Sos1 Sos2 Stef Syx Tiam-1 Tiam1 Tiam2 Trio Vav Vav1 Vav2 Vav3 Wgef mKIAA4037
G alpha (12/13) signalling events	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Ephexin-1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit alpha-12 Guanine nucleotide-binding protein subunit alpha-13 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Intersectin-1 Kalirin Mcf.2 transforming sequence Neuroepithelial cell-transforming gene 1 protein Obscurin Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 5 Plexin-B1 Protein ECT2 Proto-oncogene vav Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor (GEF) 11 Rho guanine nucleotide exchange factor (GEF) 26 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 18 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 Rho guanine nucleotide exchange factor TIAM2 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Son of sevenless homolog 1 Son of sevenless homolog 2 Thromboxane A2 receptor Transforming protein RhoA Triple functional domain protein Tyrosine-protein kinase BTK	A1IGU4 A2AAJ9 A2AWP8 A2CG49 D3YYY8 E9Q394 E9Q7D5 O88842 P27600 P27601 P27870 P29387 P30987 P35991 P50153 P52734 P61953 P62746 P62874 P62880 P62881 P63078 P63213 P63216 P70335 P70336 P70392 P97714 P97717 P97718 Q02384 Q07139 Q0KL02 Q3U5C8 Q3UTH8 Q5FWH6 Q5SSL4 Q60610 Q60875 Q60992 Q61011 Q61012 Q61016 Q61017 Q61210 Q62159 Q62245 Q64096 Q66JY6 Q66T02 Q68FM7 Q69ZK0 Q6KAU7 Q6P9R4 Q6ZPF3 Q80SZ7 Q80U35 Q80VK6 Q8BLE2 Q8BW86 Q8BWA8 Q8BY35 Q8C033 Q8CHT1 Q8CJH3 Q8K4I3 Q8R4H2 Q91X46 Q91ZT5 Q9CWR0 Q9CXP8 Q9DAS9 Q9ES28 Q9JMF3 Q9QUI0 Q9R0C8 Q9Z0R4 Q9Z206	Abr Adra1a Adra1b Adra1c Adra1d Akap13 Arha Arha2 Arhb Arhc Arhgef1 Arhgef10 Arhgef10l Arhgef11 Arhgef12 Arhgef15 Arhgef16 Arhgef17 Arhgef18 Arhgef19 Arhgef2 Arhgef25 Arhgef26 Arhgef3 Arhgef33 Arhgef37 Arhgef38 Arhgef39 Arhgef5 Arhgef6 Arhgef7 Arhgef8 Arhgef9 Bpk Brx Btk D10Ertd610e Dbs Ect2 Ese1 Fgd1 Fgd2 Fgd3 Fgd4 Geft Gm878 Gm941 Gna-12 Gna-13 Gna12 Gna13 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng1 Gng10 Gng11 Gng12 Gng13 Gng2 Gng3 Gng4 Gng5 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt2 Gngt3 Gngt4 Gngt5 Gngt7 Gngt8 Gngt9 Gpcr8 Grf2 Itsn Itsn1 Kalrn Kiaa0142 Kiaa0294 Kiaa0337 Kiaa0382 Kiaa0407 Kiaa0424 Kiaa0521 Kiaa0651 Kiaa0720 Kiaa0915 Kiaa1415 Kiaa1626 Kiaa2016 Larg Lbcl1 Lbcl2 Lfc Lsc Mcf2 Mcf2l Net1 Ngef Obscn Pak3bp Plekhg2 Plekhg5 Plxnb1 Prex1 Rasgrf2 Rhoa Rhob Rhoc Rock1 Rock2 Sos1 Sos2 Stef Syx Tbxa2r Tiam-1 Tiam1 Tiam2 Trio Vav Vav1 Vav2 Vav3 Wgef mKIAA4037
RHOB GTPase cycle	A-kinase anchor protein 13 Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Anillin Ankyrin repeat domain-containing protein SOWAHC Breakpoint cluster region protein Caveolae-associated protein 1 Caveolin-1 Cell surface glycoprotein MUC18 Citron Rho-interacting kinase DEP domain-containing protein 1B Disheveled-associated activator of morphogenesis 1 Erbin Flotillin-1 Flotillin-2 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 IQ motif containing GTPase activating protein 3 Junction plakoglobin Mcf.2 transforming sequence Neuroepithelial cell-transforming gene 1 protein Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein ECT2 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Protocadherin 7 Rac GTPase-activating protein 1 Rho GDP-dissociation inhibitor 3 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor (GEF) 11 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB Rhophilin-2 Rhotekin STE20-like serine/threonine-protein kinase Serine/threonine-protein kinase 10 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 StAR-related lipid transfer protein 13 StAR-related lipid transfer protein 8 Stomatin Synaptosomal-associated protein 23 Tight junction protein ZO-2 Transferrin receptor protein 1 Unconventional myosin-IXa Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3	A0A0A6YY83 A2AWP8 E9Q394 E9Q7D5 F8VQ29 O08808 O08908 O08917 O09044 O54724 O54988 O55098 P26450 P49025 P49817 P54116 P59281 P62746 P63024 P68033 P70268 P70335 P70336 P97393 P97433 Q02257 Q07139 Q5FWK3 Q5SSL4 Q60634 Q60875 Q60992 Q61210 Q62160 Q62351 Q64096 Q68FM7 Q69ZK0 Q6DFV3 Q6PAJ1 Q6ZQ82 Q80TH2 Q80U35 Q80Z96 Q811P8 Q8BH88 Q8BLE2 Q8BPM0 Q8BWR8 Q8BWW9 Q8C033 Q8C0J6 Q8C170 Q8C6B2 Q8K031 Q8K045 Q8K298 Q8R2Y2 Q8R4H2 Q91X46 Q91YM2 Q923Q2 Q99J31 Q9CWR0 Q9QY06 Q9R0Z9 Q9WVM1 Q9Z0U1 Q9Z206 Q9Z207	Abr Actc Actc1 Akap13 Ankrd57 Anln Arhb Arhgap1 Arhgap10 Arhgap21 Arhgap26 Arhgap32 Arhgap35 Arhgap39 Arhgap5 Arhgap7 Arhgdig Arhgef1 Arhgef10 Arhgef10l Arhgef11 Arhgef12 Arhgef17 Arhgef2 Arhgef25 Arhgef28 Arhgef3 Arhgef5 Arhgef8 Bcr Brx Cav Cav1 Cavin1 Cit Crik D10Ertd610e D15Wsu169e Daam1 Dbs Depdc1b Diap1 Diap3 Diaph1 Diaph3 Dlc1 Ect2 Epb7.2 Epb72 Erbb2ip Erbin Esa1 Flot1 Flot2 Gdi5 Geft Grit Grlf1 Iqgap3 Jup Kiaa0189 Kiaa0204 Kiaa0294 Kiaa0337 Kiaa0382 Kiaa0621 Kiaa0651 Kiaa0712 Kiaa1225 Kiaa1415 Kiaa1424 Kiaa1626 Kiaa1688 Kiaa1722 Kiaa1998 Kiaa3017 Lap2 Larg Lbcl1 Lbcl2 Lfc Lok Lpp2 Lsc M17s1 Mcam Mcf2 Mcf2l Mgcracgap Muc18 Myo9a Myo9b Myr5 Myr7 Net1 Ophn1 P190A Pcdh7 Pik3r1 Pik3r2 Pkn Pkn1 Pkn2 Pkn3 Pknbeta Prex1 Prk1 Prk2 Prkcl1 Prkcl2 Ptrf Racgap1 Rgnef Rhob Rhogap5 Rhoip2 Rhpn2 Rics Rip2 Rock1 Rock2 Rtkn Slk Snap23 Sndt Sowahc Stard12 Stard13 Stard8 Stk10 Stk2 Stom Syb3 Tfrc Tjp2 Trfr Vamp3 Vangl1 Vav2 Zo2 mKIAA4037 p190ARHOGAP
Cell-extracellular matrix interactions	Alpha-parvin Beta-parvin Fermitin family homolog 2 Filamin-A Filamin-C Filamin-binding LIM protein 1 Integrin-linked protein kinase LIM and senescent cell antigen-like-containing domain protein 1 LIM and senescent cell antigen-like-containing domain protein 2 Vasodilator-stimulated phosphoprotein	O55222 P70460 Q71FD7 Q8BTM8 Q8CIB5 Q8VHX6 Q91XD2 Q99JW4 Q9EPC1 Q9ES46	Abpl Actp Cal Fblim1 Fermt2 Fln Fln1 Fln2 Flna Flnc ILK1 ILK2 Ilk Lims1 Lims2 Parva Parvb Pinch1 Pinch2 Plekhc1 Vasp
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Histo-blood group ABO system transferase	O09160 P38649 Q9JL27	Abo Fut1 Fut2 Sec2
Negative regulation of FLT3	E3 ubiquitin-protein ligase CBL Fms-related tyrosine kinase 3 ligand Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein kinase FLT3 Receptor-type tyrosine-protein phosphatase eta SH2B adapter protein 3 Src-like-adapter 2 Src-like-adapter Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 6 Tyrosine-protein kinase ABL2 Tyrosine-protein kinase CSK Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O09039 O35717 P0CG49 P0CG50 P22682 P41241 P49772 P62983 P62984 Q00342 Q4JIM5 Q60898 Q64455 Q8R4L0 Q9JLY0	Abl2 Arg Byp Cbl Cis2 Cis4 Cish2 Cish4 Csk Flk-2 Flt-3 Flt3 Flt3l Flt3lg Lnk Ptprj Rps27a Scc1 Sh2b3 Sla Sla2 Slap Slap1 Socs2 Socs4 Socs6 Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2
Cyclin D associated events in G1	CDK-activating kinase assembly factor MAT1 Cullin-1 Cyclin-H Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase 7 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 1C Cyclin-dependent kinases regulatory subunit 1 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Polyubiquitin-B Polyubiquitin-C Protein-tyrosine kinase 6 Proto-oncogene tyrosine-protein kinase Src Retinoblastoma-associated protein Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit delta Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3 Transcription factor E2F4 Transcription factor E2F5 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O35261 P00520 P05480 P0CG49 P0CG50 P13405 P25322 P25911 P30280 P30282 P30285 P39689 P46414 P49919 P51949 P55271 P56931 P61025 P62715 P62983 P62984 P63330 P97377 Q03147 Q08639 Q61457 Q61458 Q61501 Q61502 Q62120 Q64163 Q64261 Q64434 Q64700 Q64701 Q6P1F6 Q76MZ3 Q7TNP2 Q8R0K9 Q9WTX5 Q9WTX6 Q9Z0Z3 Q9Z176 Q9Z238	Abl Abl1 Cak Ccnd1 Ccnd2 Ccnd3 Ccne Ccne1 Ccne2 Ccnh Cdk2 Cdk4 Cdk6 Cdk7 Cdkn1a Cdkn1b Cdkn1c Cdkn2 Cdkn2b Cdkn6 Cdkn7 Cip1 Cks1 Cks1b Crk2 Crk3 Crk4 Cul1 Cyl-1 Cyl-2 Cyl-3 Dp2 E2f1 E2f2 E2f3 E2f4 E2f5 Jak2 Kip2 Lyn Mat1 Mnat1 Mo15 Mpk-7 Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r2a Ppp2r3a Ppp2r3d Ppp2r6 Ptk6 Rb-1 Rb1 Rbl1 Rbl2 Rps27a Sid1334 Sik Skp1 Skp1a Skp2 Src Tfdp1 Tfdp2 Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2 Waf1
HDR through Single Strand Annealing (SSA)	ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein homolog Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA excision repair protein ERCC-1 DNA repair endonuclease XPF DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD52 homolog DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein homolog Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR Tyrosine-protein kinase ABL1	O09053 O70157 O70445 O88700 P00520 P07903 P43352 P48754 P70388 Q08297 Q3UPE3 Q5SXJ3 Q61216 Q62193 Q62388 Q6NXW6 Q6WBX7 Q6ZQF0 Q6ZQJ5 Q80YR6 Q8BMG1 Q8BQY8 Q8CHK4 Q8K3A4 Q8R323 Q8VEE4 Q99J62 Q9CQ71 Q9D0F6 Q9D4G9 Q9JKK8 Q9QWZ1 Q9QZ11 Q9QZD4 Q9R207 Q9WUK4 Q9Z0F6	Abl Abl1 Atm Atr Atrip Bach1 Bard1 Blm Brca1 Brip1 Ctip Dna2 Dna2l Ercc-1 Ercc1 Ercc4 Exo1 Fancj Gm929 Htatip Hus1 Kat5 Kiaa0083 Kiaa0259 Kiaa4069 Mre11 Mre11a Nbn Nbs1 Rad1 Rad17 Rad50 Rad51 Rad51a Rad52 Rad9 Rad9a Rad9b Rbbp8 Rec1 Reca Rfc2 Rfc3 Rfc4 Rfc5 Rhno1 Rmi1 Rmi2 Rpa1 Rpa2 Rpa3 Rpa34 Tip60 Top3 Top3a Topbp1 Wrn Xpf
Myogenesis	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 Brother of CDO C-Jun-amino-terminal kinase-interacting protein 4 Cadherin-15 Cadherin-2 Cadherin-4 Catenin alpha-1 Catenin alpha-2 Catenin beta-1 Cell adhesion molecule-related/down-regulated by oncogenes Cell division control protein 42 homolog Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 14 Myoblast determination protein 1 Myocyte-specific enhancer factor 2B Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D Myogenic factor 5 Myogenic factor 6 Myogenin Transcription factor 12 Transcription factor 4 Tyrosine-protein kinase ABL1	O08911 O54940 O55087 P00520 P10085 P12979 P15116 P15375 P24699 P26231 P33146 P39038 P47811 P60766 Q02248 Q32MD9 Q58A65 Q60722 Q61286 Q61301 Q63943 Q6AZB0 Q8CFN5 Q9WUI1	Abl Abl1 Alf1 Bnip2 Boc Catna1 Catna2 Catnb Cdc42 Cdh14 Cdh15 Cdh2 Cdh4 Cdo Cdon Crk1 Csbp1 Csbp2 Ctnna1 Ctnna2 Ctnnb1 Itf2 Jip4 Jsap2 Kiaa0516 Mapk11 Mapk12 Mapk14 Mapk8ip4 Meb Mef2b Mef2c Mef2d Mrf4 Myf-5 Myf-6 Myf5 Myf6 Myod Myod1 Myog Nip2l Prkm11 Sapk3 Sef2 Spag9 Tcf12 Tcf4
RUNX1 regulates transcription of genes involved in differentiation of HSCs	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CDK-activating kinase assembly factor MAT1 Core-binding factor subunit beta Cyclin-H Cyclin-dependent kinase 7 E3 ubiquitin-protein ligase Itchy Endothelial transcription factor GATA-2 Erythroid transcription factor Histone-lysine N-methyltransferase 2A LIM domain-binding protein 1 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type-8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Rhombotin-1 Rhombotin-2 Runt-related transcription factor 1 T-cell acute lymphocytic leukemia protein 1 homolog Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor 12 Transcriptional coactivator YAP1 Tumor protein p73 Tyrosine-protein kinase ABL1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O09061 O09100 O35226 O35593 O35955 O55234 O70435 O88685 P00520 P0CG49 P0CG50 P14685 P17679 P22091 P23772 P25801 P26516 P28063 P28076 P46471 P46938 P49722 P51949 P54775 P55200 P61290 P62192 P62196 P62334 P62983 P62984 P70195 P70662 P97371 P97372 P99026 Q03147 Q03347 Q08024 Q3TXS7 Q5SSW2 Q60692 Q61286 Q61458 Q8BG32 Q8BG41 Q8BHL8 Q8BJY1 Q8C863 Q8VDM4 Q924W9 Q99JI4 Q9CR00 Q9CWH6 Q9CX56 Q9D8W5 Q9JJP2 Q9QUM9 Q9R1P0 Q9R1P1 Q9R1P3 Q9R1P4 Q9WVJ2 Q9Z2U0 Q9Z2U1 Q9Z2X2	Abl Abl1 Alf1 All1 Aml1 Cak Cbfa2 Cbfb Ccnh Cdk7 Cdkn7 Crk4 Gata-3 Gata1 Gata2 Gata3 Gf-1 Hrx Itch Kiaa0072 Kiaa0077 Kmt2a Ldb1 Lmo1 Lmo2 Lmp10 Lmp19 Lmp2 Lmp3 Lmp7 Lmpc3 Mat1 Mc13 Mcb1 Meb Mecl1 Mll Mll1 Mmc14 Mnat1 Mo15 Mov-34 Mov34 Mpk-7 Mss1 Nli P73 P91a Pa28b1 Pad1 Pebp2ab Pebp2b Pebpb2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma7l Psma8 Psmb1 Psmb10 Psmb11 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd4 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme3 Psme4 Psmf1 Rbtn-2 Rbtn1 Rbtn2 Rhom-2 Rhom1 Ring12 Rps27a Runx1 Scl Sug1 Sug2 Tal-1 Tal1 Tbp1 Tbp7 Tcf12 Tp73 Trp73 Tstap91a Ttg1 Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2 Yap Yap1 Yap65
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	Amyloid beta precursor protein binding family B member 1 BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein homolog Cellular tumor antigen p53 DNA repair protein RAD50 Double-strand break repair protein MRE11 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Eyes absent homolog 1 Eyes absent homolog 2 Eyes absent homolog 3 Eyes absent homolog 4 Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/G Histone H2B type 1-F/J/L Histone H2B type 1-H Histone H2B type 1-K Histone H2B type 1-M Histone H2B type 1-P Histone H2B type 2-E Histone H2B type 3-B Histone H3 Histone H4 Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase NSD2 Lys-63-specific deubiquitinase BRCC36 Lysine-specific demethylase 4A Lysine-specific demethylase 4B Mediator of DNA damage checkpoint protein 1 Mitogen-activated protein kinase 8 Nibrin Polyubiquitin-B Polyubiquitin-C SUMO-conjugating enzyme UBC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Serine-protein kinase ATM Serine/threonine-protein kinase Chk2 Serine/threonine-protein phosphatase 5 Small ubiquitin-related modifier 1 TP53-binding protein 1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BAZ1B UBX domain-containing protein 1 Ubiquitin carboxyl-terminal hydrolase BAP1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I4SYN6 O08575 O70445 P00520 P02340 P0CG49 P0CG50 P10853 P10854 P27661 P46737 P48754 P61089 P62806 P62983 P62984 P63166 P63280 P70388 P70399 P70696 P97480 P97767 Q3UI43 Q4U2R1 Q5PSV9 Q5U5Q9 Q60676 Q61216 Q62388 Q64475 Q64478 Q64524 Q6ZWY9 Q80XJ2 Q8BPZ8 Q8BVE8 Q8BW72 Q8CGP0 Q8CGP1 Q8CGP2 Q8CHK4 Q8K3W0 Q8VC56 Q91VY5 Q91Y86 Q91ZW3 Q922Y1 Q99PU7 Q9D2M8 Q9JM05 Q9QXJ1 Q9R207 Q9Z191 Q9Z265 Q9Z277	Abl Abl1 Abra1 Abraxas1 Apbb1 Atm Babam1 Babam2 Bap1 Bard1 Baz1b Blu Brca1 Brcc3 Brcc36 Bre C6.1a Ccdc98 Chek2 Chk2 D19Ertd721e Eab1 Eya1 Eya2 Eya3 Eya4 Fam175a Fe65 H2a.x H2afx H2ax H2b-f H2b-j H2b-l H2b-n H2bc1 H2bc11 H2bc12 H2bc13 H2bc14 H2bc15 H2bc21 H2bc26 H2bc26-ps H2bc3 H2bc4 H2bc6 H2bc7 H2bc8 H2bc9 H2bu1 H2bu1-ps H3f4 H4-12 H4-53 H4c1 H4c11 H4c12 H4c14 H4c16 H4c2 H4c3 H4c4 H4c6 H4c8 H4c9 H4f16 Herc2 Hist1h2ba Hist1h2bb Hist1h2bc Hist1h2be Hist1h2bf Hist1h2bg Hist1h2bh Hist1h2bj Hist1h2bk Hist1h2bl Hist1h2bm Hist1h2bn Hist1h2bp Hist1h4a Hist1h4b Hist1h4c Hist1h4d Hist1h4f Hist1h4h Hist1h4i Hist1h4j Hist1h4k Hist1h4m Hist2h2be Hist2h4 Hist2h4a Hist3h2bb Hist3h2bb-ps Hist4h4 Hist5-2ax Htatip Jdf2 Jhdm3a Jhdm3b Jmjd2 Jmjd2a Jmjd2b Jnk1 Kat5 Kdm4a Kdm4b Kiaa0170 Kiaa0272 Kiaa0393 Kiaa0677 Kiaa1090 Mapk8 Mdc1 Merit40 Mms2 Mre11 Mre11a Nba1 Nbn Nbs1 Nsd2 P53 Pias4 Piasg Ppp5c Prkm8 Rad50 Rad53 Rap80 Rip110 Rir Rjs Rnf168 Rnf8 Rps27a Rxrip110 Saks1 Smarca5 Smt3c Smt3h3 Snf2h Sumo1 Th2b Tip60 Tp53 Tp53bp1 Trp53 Trp53bp1 Uba52 Uba80 Ubb Ubc Ubc9 Ubce2i Ubce9 Ubcep1 Ubcep2 Ube2i Ube2n Ube2v2 Ubl1 Ubxn1 Uev2 Uimc1 Wbscr9 Whsc1 Wstf
Role of ABL in ROBO-SLIT signaling	Roundabout homolog 1 Slit homolog 2 protein Tyrosine-protein kinase ABL1 Tyrosine-protein kinase ABL2	O89026 P00520 Q4JIM5 Q9R1B9	Abl Abl1 Abl2 Arg Dutt1 Robo1 Slit2
MAP3K8 (TPL2)-dependent MAPK1/3 activation	Cullin-1 F-box/WD repeat-containing protein 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 8 NF-kappa-B essential modulator Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C S-phase kinase-associated protein 1 TNFAIP3-interacting protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O88351 O88522 P0CG49 P0CG50 P25799 P62983 P62984 Q07174 Q5SRY7 Q60680 Q99JG7 Q9WTX5 Q9WTX6	Abin2 Btrcp2 Chuk Cot Cul1 Fbw1b Fbxw11 Fbxw1b Ikbkb Ikbkg Ikka Ikkb Map3k8 Nemo Nfkb1 Rps27a Skp1 Skp1a Tnip2 Tpl2 Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2

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