GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1126 - 1150** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Dedicator of cytokinesis protein 1 Engulfment and cell motility protein 1 Engulfment and cell motility protein 2 GTPase HRas GTPase NRas Paxillin Protein-tyrosine kinase 6 Ras GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Transforming protein RhoA	P01111 P01112 P20936 P46108 P49023 P56945 P61586 P63000 Q13882 Q14185 Q92556 Q96JJ3 Q9NRY4	ARH12 ARHA ARHGAP35 BCAR1 BRK CAS CASS1 CED12A CRK CRKAS DOCK1 ELMO1 ELMO2 GAP GRF1 GRLF1 HRAS HRAS1 KIAA0281 KIAA1722 KIAA1834 NRAS P190A PTK6 PXN RAC1 RASA RASA1 RHO12 RHOA TC25 p190ARHOGAP
RHO GTPases activate KTN1	Cell division control protein 42 homolog Kinectin Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 2 Kinesin light chain 3 Kinesin light chain 4 Kinesin-1 heavy chain Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoG Transforming protein RhoA	P33176 P60953 P61586 P63000 P84095 Q07866 Q12840 Q6P597 Q86UP2 Q9H0B6 Q9NSK0	ARH12 ARHA ARHG CDC42 CG1 KIAA0004 KIF5A KIF5B KLC KLC1 KLC2 KLC2L KLC3 KLC4 KNS KNS1 KNS2 KNSL8 KTN1 NKHC1 RAC1 RHO12 RHOA RHOG TC25
GPVI-mediated activation cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3-phosphoinositide-dependent protein kinase 1 C-type lectin domain family 1 member B Cell division control protein 42 homolog Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 High affinity immunoglobulin epsilon receptor subunit gamma Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 Platelet glycoprotein VI Podoplanin Protein kinase C zeta type Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoG Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	O00459 O15530 O43561 O95866 P06239 P06241 P07948 P15153 P15498 P16885 P27986 P29350 P30273 P42336 P42338 P43405 P48736 P52735 P60953 P61586 P62745 P63000 P84095 Q05513 Q06124 Q13094 Q5UE93 Q86YL7 Q8WYR1 Q92569 Q9HCN6 Q9P126 Q9UKW4	ARH12 ARH6 ARHA ARHB ARHG C17orf38 C6orf25 CDC42 CLEC1B CLEC2 FCER1G FYN G6B G6B-B GP36 GP6 GRB1 HCP JTK8 LAT LCK LCP2 LYN MPIG6B PDK1 PDPK1 PDPN PIK3C1 PIK3CA PIK3CB PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIK3R6 PKC2 PLCG2 PRKCZ PTP1C PTP2C PTPN11 PTPN6 RAC1 RAC2 RHO12 RHOA RHOB RHOG SHPTP2 SYK TC25 VAV VAV1 VAV2 VAV3
RHO GTPases Activate Rhotekin and Rhophilins	Protein lin-7 homolog B Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Rhophilin-1 Rhophilin-2 Rhotekin Ropporin-1A Tax1-binding protein 3 Transforming protein RhoA	O14907 P08134 P61586 P62745 Q8IUC4 Q8TCX5 Q9BST9 Q9HAP6 Q9HAT0	ARH12 ARH6 ARH9 ARHA ARHB ARHC KIAA1929 LIN7B MALS2 RHO12 RHOA RHOB RHOC RHPN1 RHPN2 ROPN1 ROPN1A RTKN RTKN1 TAX1BP3 TIP1 VELI2
RHO GTPases Activate ROCKs	Cofilin-1 LIM domain kinase 1 LIM domain kinase 2 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein kinase PAK 1 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14950 O14974 O60237 O75116 P08134 P23528 P24844 P35579 P35580 P35749 P53667 P53671 P60660 P61586 P62140 P62745 Q13153 Q13464 Q7Z406	ARH12 ARH6 ARH9 ARHA ARHB ARHC CFL CFL1 KIAA0619 KIAA0866 KIAA2034 LIMK LIMK1 LIMK2 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PAK1 PPP1CB PPP1R12A PPP1R12B RHO12 RHOA RHOB RHOC ROCK1 ROCK2
RHO GTPases activate CIT	Citron Rho-interacting kinase Cyclin-dependent kinase inhibitor 1B Disks large homolog 4 Kinesin-like protein KIF14 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Protein regulator of cytokinesis 1 Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14578 O14950 O14974 O43663 O60237 P08134 P24844 P35579 P35580 P35749 P46527 P60660 P61586 P62140 P62745 P63000 P78352 Q15058 Q7Z406	ARH12 ARH6 ARH9 ARHA ARHB ARHC CDKN1B CIT CRIK DLG4 KIAA0042 KIAA0866 KIAA0949 KIAA2034 KIF14 KIP1 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PPP1CB PPP1R12A PPP1R12B PRC1 PSD95 RAC1 RHO12 RHOA RHOB RHOC STK21 TC25 p27
RHO GTPases activate PKNs	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 3-phosphoinositide-dependent protein kinase 1 M-phase inducer phosphatase 3 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Protein phosphatase 1 regulatory subunit 14A Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase N3 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14950 O14974 O15530 O60237 P08134 P24844 P27348 P30307 P31946 P31947 P35579 P35580 P35749 P60660 P61586 P61981 P62140 P62258 P62745 P63000 P63104 Q04917 Q13153 Q16512 Q16513 Q6P5Z2 Q7Z406 Q96A00	ARH12 ARH6 ARH9 ARHA ARHB ARHC CDC25C CPI17 HME1 KIAA0866 KIAA2034 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PAK1 PDK1 PDPK1 PKN PKN1 PKN2 PKN3 PKNBETA PPP1CB PPP1INL PPP1R12A PPP1R12B PPP1R14A PRK1 PRK2 PRKCL1 PRKCL2 RAC1 RHO12 RHOA RHOB RHOC SFN TC25 YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Sema4D induced cell migration and growth-cone collapse	LIM domain kinase 1 LIM domain kinase 2 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Plexin-B1 Receptor tyrosine-protein kinase erbB-2 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein Rho6 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Semaphorin-4D Transforming protein RhoA	O14950 O15085 O43157 O75116 P04626 P08134 P24844 P35579 P35580 P35749 P53667 P53671 P60660 P61586 P62745 Q13464 Q7Z406 Q92730 Q92854 Q9NZN5	ARH12 ARH6 ARH9 ARHA ARHB ARHC ARHGEF11 ARHGEF12 C9orf164 CD100 ERBB2 HER2 KIAA0380 KIAA0382 KIAA0407 KIAA0619 KIAA0866 KIAA2034 LARG LIMK LIMK1 LIMK2 MLC2 MLN19 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYRL2 NEU NGL PLXN5 PLXNB1 RHO12 RHO6 RHOA RHOB RHOC RND1 ROCK1 ROCK2 SEMA4D SEMAJ SEP
Vitamin D (calciferol) metabolism	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial Cubilin E3 SUMO-protein ligase PIAS4 Legumain Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 2 Vitamin D 25-hydroxylase Vitamin D-binding protein Vitamin D3 receptor	O15528 O60494 P02774 P11473 P61956 P63279 P98164 Q07973 Q5SW96 Q6VVX0 Q8N2W9 Q99538	ARH CUBN CYP1ALPHA CYP24 CYP24A1 CYP27B CYP27B1 CYP2R1 GC IFCR LDLRAP1 LGMN LRP2 NR1I1 PIAS4 PIASG PRSC1 SMT3B SMT3H2 SUMO2 UBC9 UBCE9 UBE2I VDR
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Argininosuccinate synthase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 Mitochondrial ornithine transporter 2 N-acetylglutamate synthase, mitochondrial NmrA-like family domain-containing protein 1 Ornithine transcarbamylase, mitochondrial	P00480 P00966 P04424 P05089 P31327 P78540 Q8N159 Q9BXI2 Q9HBL8 Q9Y619	ARG1 ARG2 ASL ASS ASS1 CPS1 HSCARG NAGS NMRAL1 ORC1 ORC2 ORNT1 ORNT2 OTC SLC25A15 SLC25A2
Trafficking of myristoylated proteins to the cilium	ADP-ribosylation factor-like protein 3 Cystin-1 Nephrocystin-3 Protein XRP2 Protein unc-119 homolog B	A6NIH7 O75695 P36405 Q717R9 Q7Z494	ARFL3 ARL3 CYS1 KIAA2000 NPHP3 RP2 UNC119B
MET receptor recycling	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA3 Adapter molecule crk Crk-like protein GRB2-associated-binding protein 1 Hepatocyte growth factor receptor Hepatocyte growth factor Ras-related protein Rab-4A Ras-related protein Rab-4B	P08581 P14210 P20338 P46108 P46109 P61018 P62330 Q13480 Q9NZ52	ARF6 CRK CRKL GAB1 GGA3 HGF HPTA KIAA0154 MET RAB4 RAB4A RAB4B
TBC/RABGAPs	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA1 ADP-ribosylation factor-binding protein GGA2 ADP-ribosylation factor-binding protein GGA3 Carabin Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein Genome polyprotein Hamartin Microtubule-associated proteins 1A/1B light chain 3B Optineurin Rab GTPase-activating protein 1 Rab GTPase-binding effector protein 1 Rab5 GDP/GTP exchange factor Ras-related protein Rab-11A Ras-related protein Rab-11B Ras-related protein Rab-33A Ras-related protein Rab-33B Ras-related protein Rab-35 Ras-related protein Rab-4A Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-7a Ras-related protein Rab-7b Ras-related protein Rab-8A Ras-related protein Rab-8B Serine/threonine-protein kinase ULK1 Synaptotagmin-like protein 1 TBC1 domain family member 10A TBC1 domain family member 10B TBC1 domain family member 13 TBC1 domain family member 14 TBC1 domain family member 15 TBC1 domain family member 16 TBC1 domain family member 17 TBC1 domain family member 20 TBC1 domain family member 24 TBC1 domain family member 25 TBC1 domain family member 2A TBC1 domain family member 3 TBC1 domain family member 7 Tuberin	O75385 O95166 P20338 P20339 P20340 P27958 P49815 P51148 P51149 P60520 P61006 P61020 P62330 P62491 Q14088 Q15276 Q15286 Q15907 Q3MII6 Q4KMP7 Q8IV04 Q8IYJ3 Q8IZP1 Q8TBP0 Q8TC07 Q92574 Q92930 Q96AH8 Q96BZ9 Q96CV9 Q9BXI6 Q9BYX2 Q9GZQ8 Q9H082 Q9HA65 Q9NRW1 Q9NVG8 Q9NZ52 Q9P0N9 Q9P2M4 Q9UJ41 Q9UJY4 Q9UJY5 Q9ULP9 Q9Y3P9	ARF6 C20orf140 EPI64 FIP2 FLC3A FLC3B GABARAP GABARAPL2 GEF2 GGA1 GGA2 GGA3 GLC1E HIP7 HYPL KIAA0154 KIAA0243 KIAA0722 KIAA1080 KIAA1171 KIAA1322 MAP1ALC3 MAP1LC3B MEL NRP OATL1 OPTN PARIS1 PP8997 PRC17 RAB11 RAB11A RAB11B RAB1C RAB33A RAB33B RAB35 RAB4 RAB4A RAB5 RAB5A RAB5B RAB5C RAB5EP RAB6 RAB6A RAB6B RAB7 RAB7A RAB7B RAB8 RAB8A RAB8B RABEP1 RABEX5 RABGAP1 RABGEF1 RABL RABPT5 RABPT5A RABS10 RAY SLP1 SYTL1 TBC1D10 TBC1D10A TBC1D10B TBC1D10C TBC1D13 TBC1D14 TBC1D15 TBC1D16 TBC1D17 TBC1D2 TBC1D20 TBC1D24 TBC1D25 TBC1D2A TBC1D3 TBC1D3A TBC1D7 TBC7 TSC TSC1 TSC2 TSC4 ULK1 YPT3
VxPx cargo-targeting to cilium	ADP-ribosylation factor 4 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Cyclic nucleotide-gated channel alpha-2 Cyclic nucleotide-gated channel alpha-4 Cyclic nucleotide-gated channel beta-1 Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 4 Exocyst complex component 5 Exocyst complex component 6 Exocyst complex component 7 Exocyst complex component 8 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Polycystin-1 Polycystin-2 Rab-3A-interacting protein Rab11 family-interacting protein 3 Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	O00471 O60645 O75154 P08100 P18085 P61006 P62491 P98161 Q13563 Q14028 Q16280 Q8IV77 Q8IYI6 Q8TAG9 Q92538 Q96A65 Q96KP1 Q96QF0 Q9NV70 Q9ULH1 Q9UPT5	ARF2 ARF4 ARFO1 ASAP1 CNCA CNCA1 CNCG2 CNCG3L CNCG4 CNGA2 CNGA4 CNGB1 DDEF1 EXO70 EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6 EXOC7 EXOC8 GBF1 KIAA0248 KIAA0665 KIAA1067 KIAA1249 KIAA1699 MEL OPN2 PAG2 PKD1 PKD2 RAB11 RAB11A RAB11FIP3 RAB3IP RAB8 RAB8A RABIN8 RCNC2 RHO SEC10 SEC10L1 SEC15A SEC15L SEC15L1 SEC3 SEC3L1 SEC5 SEC5L1 SEC6 SEC6L1 SEC8 SEC8L1 TRPP2
trans-Golgi Network Vesicle Budding	ADP-ribosylation factor 1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Synaptosomal-associated protein 23 Syntaxin-4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	O00161 P51809 P63027 P84077 Q12846 Q92538 Q9BV40	ARF1 GBF1 KIAA0248 SNAP23 STX4 STX4A SYB2 SYBL1 VAMP2 VAMP7 VAMP8
Glycosphingolipid transport	ADP-ribosylation factor 1 Battenin Ceramide-1-phosphate transfer protein Extended synaptotagmin-1 Extended synaptotagmin-2 Extended synaptotagmin-3 Glycolipid transfer protein Pleckstrin homology domain-containing family A member 8	A0FGR8 A0FGR9 P84077 Q13286 Q5TA50 Q96JA3 Q9BSJ8 Q9NZD2	ARF1 BTS CLN3 CPTP ESYT1 ESYT2 ESYT3 FAM62A FAM62B FAM62C FAPP2 GLTP GLTPD1 KIAA0747 KIAA1228 MBC2 PLEKHA8
Synthesis of PIPs at the plasma membrane	ADP-ribosylation factor 1 Cytoplasmic tyrosine-protein kinase BMX Inositol polyphosphate 4-phosphatase type II Inositol polyphosphate 5-phosphatase K Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Myotubularin-related protein 13 Myotubularin-related protein 14 Myotubularin-related protein 1 Myotubularin-related protein 2 Myotubularin-related protein 3 Myotubularin-related protein 6 Myotubularin-related protein 8 Myotubularin-related protein 9 Myotubularin Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 Pleckstrin homology domain-containing family A member 1 Pleckstrin homology domain-containing family A member 2 Pleckstrin homology domain-containing family A member 3 Pleckstrin homology domain-containing family A member 4 Pleckstrin homology domain-containing family A member 5 Pleckstrin homology domain-containing family A member 6 Pleckstrin homology domain-containing family A member 8 RUN and FYVE domain-containing protein 1 Ras-related protein Rab-14 Ras-related protein Rab-4A Ras-related protein Rab-5A Synaptojanin-1 Synaptojanin-2 Tyrosine-protein phosphatase non-receptor type 13	O00329 O00443 O00459 O00750 O14986 O15056 O15327 O15357 O43426 O60331 O75747 P20338 P20339 P27986 P42336 P42338 P48426 P48736 P51813 P60484 P61106 P78356 P84077 Q01968 Q12923 Q13496 Q13613 Q13614 Q13615 Q15735 Q5UE93 Q86WG5 Q8NCE2 Q8TBX8 Q8TCG2 Q8WYR1 Q92569 Q92835 Q96EF0 Q96JA3 Q96PE3 Q96QG7 Q96T51 Q99755 Q9BT40 Q9BTU6 Q9H4M7 Q9HAU0 Q9HB19 Q9HB20 Q9HB21 Q9Y217 Q9Y2H5	ARF1 BMX C17orf38 C3orf29 C8orf9 CG2 CMT4B2 FAPP1 FAPP2 GRB1 INPP4A INPP4B INPP5D INPP5J INPP5K INPPL1 KIAA0348 KIAA0371 KIAA0589 KIAA0910 KIAA0969 KIAA1073 KIAA1686 KIAA1766 MMAC1 MTM1 MTMR1 MTMR13 MTMR14 MTMR2 MTMR3 MTMR6 MTMR8 MTMR9 OCRL OCRL1 PEPP1 PEPP2 PEPP3 PI4K2A PI4K2B PI5P4KA PIB5PA PIK3C1 PIK3C2A PIK3C2B PIK3C2G PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIK3R6 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PIP5K2 PIP5K2A PIP5K2B PIP5K2C PIPP PLEKHA1 PLEKHA2 PLEKHA3 PLEKHA4 PLEKHA5 PLEKHA6 PLEKHA8 PNP1 PPS PTEN PTP1E PTPL1 PTPN13 RAB14 RAB4 RAB4A RAB5 RAB5A RABIP4 RUFY1 SBF2 SHIP SHIP1 SHIP2 SKIP STM7 SYNJ1 SYNJ2 TAPP1 TAPP2 TEP1 ZFYVE10 ZFYVE12
Synthesis of PIPs at the Golgi membrane	1-phosphatidylinositol 3-phosphate 5-kinase ADP-ribosylation factor 1 ADP-ribosylation factor 3 Inositol polyphosphate 5-phosphatase OCRL Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase alpha Phosphatidylinositol 4-kinase beta Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol polyphosphate 5-phosphatase type IV Phosphatidylinositol-3-phosphatase SAC1 Phosphoinositide 3-kinase regulatory subunit 4 Polyphosphoinositide phosphatase Protein VAC14 homolog Putative tyrosine-protein phosphatase TPTE	O00443 O75747 P42356 P56180 P61204 P84077 Q01968 Q08AM6 Q6XPS3 Q8NEB9 Q8TCG2 Q92562 Q99570 Q9BTU6 Q9NRR6 Q9NTJ5 Q9UBF8 Q9Y2I7	ARF1 ARF3 FIG4 INPP5E KIAA0274 KIAA0851 KIAA0981 OCRL OCRL1 PI4K2A PI4K2B PI4KA PI4KB PIK3C2A PIK3C2G PIK3C3 PIK3R4 PIK4 PIK4CA PIK4CB PIKFYVE PIP5K3 SAC1 SAC3 SACM1L TAX1BP2 TPIP TPTE TPTE2 TRX VAC14 VPS15 VPS34
Inhibition of Signaling by Overexpressed EGFR	Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	O14944 P00533 P01133 P01135 P15514 P35070 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 SDGF TGFA
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	O14944 P00533 P01133 P01135 P15514 P19174 P35070 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 PLC1 PLCG1 SDGF TGFA
GRB2 events in EGFR signaling	Amphiregulin Epidermal growth factor receptor Epigen GTPase HRas GTPase NRas Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha Son of sevenless homolog 1	O14944 P00533 P01111 P01112 P01133 P01135 P15514 P35070 Q07889 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 HRAS HRAS1 NRAS SDGF SOS1 TGFA
SHC1 events in EGFR signaling	Amphiregulin Epidermal growth factor receptor Epigen GTPase HRas GTPase NRas Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha SHC-transforming protein 1 Son of sevenless homolog 1	O14944 P00533 P01111 P01112 P01133 P01135 P15514 P29353 P35070 Q07889 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 HRAS HRAS1 NRAS SDGF SHC SHC1 SHCA SOS1 TGFA
GAB1 signalosome	Amphiregulin Epidermal growth factor receptor Epigen GRB2-associated-binding protein 1 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha Tyrosine-protein kinase CSK Tyrosine-protein phosphatase non-receptor type 11	O14944 P00533 P01133 P01135 P12931 P15514 P27986 P35070 P41240 P42336 P49023 Q06124 Q13480 Q6UW88 Q99075 Q9NWQ8	AREG AREGB BTC CBP CSK DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG GAB1 GRB1 HBEGF HEGFL HER1 PAG PAG1 PIK3CA PIK3R1 PTP2C PTPN11 PXN SDGF SHPTP2 SRC SRC1 TGFA
NFE2L2 regulating tumorigenic genes	Amphiregulin Apoptosis regulator Bcl-2 Bcl-2-like protein 1 CREB-binding protein Histone acetyltransferase p300 Neurogenic locus notch homolog protein 1 Nuclear factor erythroid 2-related factor 2 Platelet-derived growth factor subunit A Pro-epidermal growth factor Transcription factor MafK Transcription factor Sp1	O60675 P01133 P04085 P08047 P10415 P15514 P46531 Q07817 Q09472 Q16236 Q92793	AREG AREGB BCL2 BCL2L BCL2L1 BCLX CBP CREBBP EGF EP300 MAFK NFE2L2 NOTCH1 NRF2 P300 PDGF1 PDGFA SDGF SP1 TAN1 TSFP1
Constitutive Signaling by Aberrant PI3K in Cancer	Amphiregulin B-lymphocyte antigen CD19 Beta-klotho Epidermal growth factor receptor Epigen Estrogen receptor beta Estrogen receptor Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphoinositide 3-kinase adapter protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Protransforming growth factor alpha Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Rho-related GTP-binding protein RhoG Striatin T-cell receptor-associated transmembrane adapter 1 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 11	O00329 O00459 O14511 O14944 O15520 O43320 O43815 O76093 O95750 P00533 P01127 P01133 P01135 P03372 P04626 P05230 P06239 P06241 P08581 P08620 P09038 P09619 P10721 P10747 P10767 P11487 P12931 P14210 P15153 P15391 P15498 P15514 P16234 P21781 P22455 P27986 P31371 P33681 P35070 P35568 P36888 P42081 P42336 P42338 P49771 P56975 P63000 P84095 Q02297 Q06124 Q13480 Q6PIZ9 Q6UW88 Q6ZUJ8 Q86Z14 Q8WU20 Q8WWG1 Q92569 Q92731 Q99075 Q9GZV9 Q9HCT0 Q9NP95 Q9UQC2 Q9Y4H2	AREG AREGB ARHG BCAP BTC CD135 CD19 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ESR ESR1 ESR2 ESTRB FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GGF GRB1 HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRGA HST HST2 HSTF1 HSTF2 HYPF INT2 IRS1 IRS2 JTK2 KGF KIAA0571 KIT KLB KS3 LAB7 LCK MET MLN19 NDF NEU NGL NR3A1 NR3A2 NRG1 NRG2 NRG3 NRG4 NTAK PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PIK3AP1 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTP2C PTPN11 RAC1 RAC2 RHEPDGFRA RHOG SCFR SDGF SHPTP2 SIS SMDF SRC SRC1 STK1 STRN TC25 TCRIM TGFA TKF TRAT1 VAV VAV1

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