GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **601 - 625** of **2074** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Negative feedback regulation of MAPK pathway	Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Serine/threonine-protein kinase B-raf	P04049 P15056 P27361 P28482 P36507 Q02750	BRAF BRAF1 ERK1 ERK2 MAP2K1 MAP2K2 MAPK1 MAPK3 MEK1 MEK2 MKK2 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1	Homo sapiens (human)
Thyroxine biosynthesis	Dual oxidase 1 Dual oxidase 2 Glycoprotein hormones alpha chain Iodotyrosine deiodinase 1 Sodium/iodide cotransporter Thyroid peroxidase Thyrotropin subunit beta	P01215 P01222 P07202 Q6PHW0 Q92911 Q9NRD8 Q9NRD9	C6orf71 CGA DEHAL1 DUOX DUOX1 DUOX2 IYD LNOX1 LNOX2 NIS SLC5A5 THOX1 THOX2 TPO TSHB	Homo sapiens (human)
C6 deamination of adenosine	Double-stranded RNA-specific adenosine deaminase Double-stranded RNA-specific editase 1	P55265 P78563	ADAR ADAR1 ADAR2 ADARB1 DRADA2 DSRAD G1P1 IFI4 RED1	Homo sapiens (human)
Formation of editosomes by ADAR proteins	Double-stranded RNA-specific adenosine deaminase Double-stranded RNA-specific editase 1	P55265 P78563	ADAR ADAR1 ADAR2 ADARB1 DRADA2 DSRAD G1P1 IFI4 RED1	Homo sapiens (human)
SRP-dependent cotranslational protein targeting to membrane	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Protein transport protein Sec61 subunit alpha isoform 1 Protein transport protein Sec61 subunit alpha isoform 2 Protein transport protein Sec61 subunit beta Protein transport protein Sec61 subunit gamma Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Signal recognition particle 14 kDa protein Signal recognition particle 19 kDa protein Signal recognition particle 9 kDa protein Signal recognition particle receptor subunit alpha Signal recognition particle receptor subunit beta Signal recognition particle subunit SRP54 Signal recognition particle subunit SRP68 Signal recognition particle subunit SRP72 Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Translocating chain-associated membrane protein 1 Translocon-associated protein subunit alpha Translocon-associated protein subunit beta Translocon-associated protein subunit delta Translocon-associated protein subunit gamma Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O76094 P04843 P04844 P05386 P05387 P05388 P08240 P08708 P08865 P09132 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P37108 P39019 P39023 P39656 P40429 P42677 P42766 P43307 P43308 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P49458 P50914 P51571 P60059 P60468 P60866 P61009 P61011 P61247 P61254 P61313 P61353 P61513 P61619 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P67812 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q15005 Q15629 Q6P5R6 Q71UM5 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q9BY50 Q9H9S3 Q9UHB9 Q9UNL2 Q9UNX3 Q9Y3U8 Q9Y5M8 Q9Y6A9	BBC1 CCG2 D11S2243E D6S218E DDOST DXS648E EC45 FAU FTE1 KIAA0102 KIAA0115 LAMBR LAMR1 MFTL MPS1 NEDD6 OST48 QM RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPN1 RPN2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SEC11A SEC11C SEC11L1 SEC11L3 SEC61A SEC61A1 SEC61A2 SEC61B SEC61G SPC12 SPC18 SPC21 SPC22 SPC25 SPCS1 SPCS2 SPCS3 SPCS4A SPCS4C SRP14 SRP19 SRP54 SRP68 SRP72 SRP9 SRPR SRPRA SRPRB SSR1 SSR2 SSR3 SSR4 SURF-3 SURF3 TRAM TRAM1 TRAPA TRAPB TRAPD TRAPG TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
Defective ALG6 causes CDG-1c	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase	Q9Y672	ALG6	Homo sapiens (human)
Synthesis of glycosylphosphatidylinositol (GPI)	Dolichol phosphate-mannose biosynthesis regulatory protein GPI ethanolamine phosphate transferase 1 GPI ethanolamine phosphate transferase 2 GPI ethanolamine phosphate transferase 3 GPI mannosyltransferase 1 GPI mannosyltransferase 2 GPI mannosyltransferase 3 GPI mannosyltransferase 4 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase Phosphatidylinositol N-acetylglucosaminyltransferase subunit A Phosphatidylinositol N-acetylglucosaminyltransferase subunit C Phosphatidylinositol N-acetylglucosaminyltransferase subunit H Phosphatidylinositol N-acetylglucosaminyltransferase subunit P Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Phosphatidylinositol-glycan biosynthesis class F protein Phosphatidylinositol-glycan biosynthesis class W protein Phosphatidylinositol-glycan biosynthesis class X protein	O94777 O95427 P37287 P57054 Q07326 Q14442 Q3MUY2 Q5H8A4 Q7Z7B1 Q86VD9 Q8TBF5 Q8TEQ8 Q92521 Q92535 Q9H3S5 Q9NUD9 Q9Y2B2	DCRC DPM2 DSCR5 DSCRC GPI2 GPI7 MCD4 PIGA PIGB PIGC PIGF PIGG PIGH PIGL PIGM PIGN PIGO PIGP PIGV PIGW PIGX PIGY PIGZ SMP3	Homo sapiens (human)
Synthesis of dolichyl-phosphate mannose	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)
Defective DPM1 causes CDG-1e	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)
Defective DPM3 causes CDG-1o	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)
Defective DPM2 causes CDG-1u	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)
Defective ALG3 causes CDG-1d	Dol-P-Man	Q92685	ALG3 NOT NOT56L	Homo sapiens (human)	G59406KS
Viral mRNA Translation	DnaJ homolog subfamily C member 3 G-rich sequence factor 1 Hemagglutinin Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Matrix protein 1 Matrix protein 2 Neuraminidase Non-structural protein 1 Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 Protein PB1-F2 RNA-directed RNA polymerase catalytic subunit Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03496 P03508 P05386 P05387 P05388 P06821 P08708 P08865 P0C0U1 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P39019 P39023 P40429 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P50914 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q12849 Q13217 Q6P5R6 Q71UM5 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q9UNX3 Q9Y3U8	BBC1 CCG2 D11S2243E D6S218E DNAJC3 DXS648E EC45 FAU FTE1 GRSF1 HA LAMBR LAMR1 M MFTL MPS1 NA NEDD6 NP NS P58IPK PA PB1 PB2 PRKRI QM RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SURF-3 SURF3 TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
Signaling by ERBB4	Disks large homolog 4 Epidermal growth factor receptor Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit beta-1 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid receptor subunit gamma-3 Gamma-aminobutyric acid receptor subunit theta Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor	O14511 O14944 P00533 P01133 P14867 P18505 P18507 P28472 P35070 P47870 P56975 P78352 Q02297 Q8WWG1 Q99075 Q99928 Q9UN88	BTC DLG4 DTR DTS EGF EGFR ERBB ERBB1 EREG GABRA1 GABRB1 GABRB2 GABRB3 GABRG2 GABRG3 GABRQ GGF HBEGF HEGFL HER1 HGL HRGA NDF NRG1 NRG2 NRG3 NRG4 NTAK PSD95 SMDF	Homo sapiens (human)
Synaptic adhesion-like molecules	Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Flotillin-1 Flotillin-2 Glutamate receptor 1 Glutamate receptor 3 Glutamate receptor 4 Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat and fibronectin type III domain-containing protein 1 Leucine-rich repeat and fibronectin type-III domain-containing protein 2 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 Leucine-rich repeat and fibronectin type-III domain-containing protein 4 Receptor-type tyrosine-protein phosphatase F Receptor-type tyrosine-protein phosphatase S Receptor-type tyrosine-protein phosphatase delta Reticulon-3	O15399 O75955 O95197 P10586 P23468 P42261 P42263 P48058 P78352 Q05586 Q12879 Q12959 Q13224 Q13332 Q14254 Q14957 Q6PJG9 Q92796 Q9BTN0 Q9P244 Q9ULH4	ASYIP DLG1 DLG3 DLG4 ESA1 FLOT1 FLOT2 GLUA1 GLUH1 GLUR1 GLUR3 GLUR4 GLURC GRIA1 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GluA3 GluA4 GluN2D KIAA1232 KIAA1246 KIAA1484 LAR LRFN1 LRFN2 LRFN3 LRFN4 M17S1 NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D NSPL2 PSD95 PTPRD PTPRF PTPRS RTN3 SALM1 SALM2 SALM3 SALM4	Homo sapiens (human)
Regulated proteolysis of p75NTR	Disintegrin and metalloproteinase domain-containing protein 17 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Nicastrin Nuclear factor NF-kappa-B p105 subunit Presenilin-1 Presenilin-2 TNF receptor-associated factor 6 Transcription factor p65 Tumor necrosis factor receptor superfamily member 16	P08138 P19838 P49768 P49810 P78536 Q04206 Q8WW43 Q92542 Q96BI3 Q9NZ42 Q9Y4K3	AD3 AD4 ADAM17 APH1A APH1B CSVP KIAA0253 NCSTN NFKB1 NFKB3 NGFR PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RELA RNF85 STM2 TACE TNFRSF16 TRAF6	Homo sapiens (human)
CD163 mediating an anti-inflammatory response	Disintegrin and metalloproteinase domain-containing protein 17 Furin Inactive rhomboid protein 2 Interleukin-10 Interleukin-6 Mitogen-activated protein kinase 14 Myosin-9 Scavenger receptor cysteine-rich type 1 protein M130 Serine/threonine-protein kinase PLK2	P05231 P09958 P22301 P35579 P78536 Q16539 Q6PJF5 Q86VB7 Q9NYY3	ADAM17 CD163 CSBP CSBP1 CSBP2 CSPB1 CSVP FUR FURIN IFNB2 IL10 IL6 IRHOM2 M130 MAPK14 MXI2 MYH9 PACE PCSK3 PLK2 RHBDF2 RHBDL5 RHBDL6 SAPK2A SNK TACE	Homo sapiens (human)
Invadopodia formation	Disintegrin and metalloproteinase domain-containing protein 12 Disintegrin and metalloproteinase domain-containing protein 15 Disintegrin and metalloproteinase domain-containing protein 19 SH3 and PX domain-containing protein 2A	O43184 Q13444 Q5TCZ1 Q9H013	ADAM12 ADAM15 ADAM19 FISH KIAA0418 MDC15 MLTN MLTNB SH3MD1 SH3PXD2A TKS5	Homo sapiens (human)
LGI-ADAM interactions	Disintegrin and metalloproteinase domain-containing protein 11 Disintegrin and metalloproteinase domain-containing protein 22 Disintegrin and metalloproteinase domain-containing protein 23 Disks large homolog 4 Leucine-rich glioma-inactivated protein 1 Leucine-rich repeat LGI family member 2 Leucine-rich repeat LGI family member 3 Leucine-rich repeat LGI family member 4 Syntaxin-1A Syntaxin-1B Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-3 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-8 subunit	O60359 O75077 O75078 O95970 P61266 P78352 Q16623 Q8N0V4 Q8N135 Q8N145 Q8WXS5 Q9P0K1 Q9UBN1 Q9Y698	ADAM11 ADAM22 ADAM23 CACNG2 CACNG3 CACNG4 CACNG6 CACNG8 DLG4 EPT KIAA1916 LGI1 LGI2 LGI3 LGI4 LGIL2 LGIL3 LGIL4 MDC MDC2 MDC3 PSD95 STX1 STX1A STX1B STX1B1 STX1B2	Homo sapiens (human)
PCP/CE pathway	Disheveled-associated activator of morphogenesis 1 Frizzled-1 Frizzled-3 Frizzled-6 Frizzled-7 Profilin-1 Protein Wnt-11 Protein Wnt-4 Protein Wnt-5a Protein Wnt-5b Proto-oncogene Wnt-1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Ras-related C3 botulinum toxin substrate 3 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Transforming protein RhoA Tyrosine-protein kinase RYK Tyrosine-protein kinase transmembrane receptor ROR2 Vang-like protein 2	O14640 O14641 O60353 O75084 O96014 P04628 P07737 P15153 P34925 P41221 P56705 P60763 P61586 P63000 Q01974 Q92997 Q9H1J7 Q9NPG1 Q9ULK5 Q9UP38 Q9Y4D1	ARH12 ARHA DAAM1 DVL1 DVL2 DVL3 FZD1 FZD3 FZD6 FZD7 INT1 JTK5A KIAA0208 KIAA0666 KIAA1215 NTRKR2 PFN1 RAC1 RAC2 RAC3 RHO12 RHOA ROR2 RYK STB1 TC25 VANGL2 WNT1 WNT11 WNT4 WNT5A WNT5B	Homo sapiens (human)
Reelin signalling pathway	Disabled homolog 1 Reelin SH3 domain-containing kinase-binding protein 1 Tyrosine-protein kinase Fyn Very low-density lipoprotein receptor	O75553 P06241 P78509 P98155 Q96B97	CIN85 DAB1 FYN RELN SH3KBP1 VLDLR	Homo sapiens (human)
Synthesis of pyrophosphates in the cytosol	Diphosphoinositol polyphosphate phosphohydrolase 1 Diphosphoinositol polyphosphate phosphohydrolase 2 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha Diphosphoinositol polyphosphate phosphohydrolase 3-beta Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 Inositol hexakisphosphate kinase 1 Inositol hexakisphosphate kinase 3 Inositol-pentakisphosphate 2-kinase Inositol-tetrakisphosphate 1-kinase	O43314 O95989 Q13572 Q6PFW1 Q8NFP7 Q92551 Q96G61 Q96PC2 Q9H8X2 Q9NZJ9	APS1 APS2 C9orf12 DIPP DIPP1 DIPP2 DIPP3A DIPP3B HISPPD1 HISPPD2A IHPK1 IHPK3 IP6K IP6K1 IP6K3 IPPK IPS1 ITPK1 KIAA0263 KIAA0377 KIAA0433 KIAA0487 NUDT10 NUDT11 NUDT3 NUDT4 PPIP5K1 PPIP5K2 VIP1 VIP2	Homo sapiens (human)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Gastric inhibitory polypeptide Glucose-dependent insulinotropic receptor Insulin gene enhancer protein ISL-1 Neuroendocrine convertase 1 Paired box protein Pax-6 Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Transcription factor GATA-4	O14842 P09681 P26367 P27487 P29120 P43694 P61009 P61371 P67812 Q15005 Q8TDV5 Q9BY50 Q9Y6A9	ADCP2 AN2 CD26 DPP4 FFAR1 GATA4 GIP GPR119 GPR40 ISL1 KIAA0102 NEC1 PAX6 PCSK1 SEC11A SEC11C SEC11L1 SEC11L3 SPC12 SPC18 SPC21 SPC22 SPC25 SPCS1 SPCS2 SPCS3 SPCS4A SPCS4C	Homo sapiens (human)
Presynaptic depolarization and calcium channel opening	Dihydropyridine receptor alpha 2 subunit Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent L-type calcium channel subunit beta-4 Voltage-dependent N-type calcium channel subunit alpha-1B Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2 Voltage-dependent calcium channel subunit alpha-2/delta-3	O00305 O00555 P54284 Q00975 Q02641 Q08289 Q15878 Q8IZS8 Q9NY47 Q9UBN1 Q9UIU0 Q9Y698	CACH4 CACH5 CACH6 CACN3 CACNA1A CACNA1B CACNA1E CACNA2D1 CACNA2D2 CACNA2D3 CACNB1 CACNB2 CACNB3 CACNB4 CACNG2 CACNG4 CACNL1A4 CACNL1A5 CACNL1A6 CACNLB1 CACNLB2 CACNLB3 CACNLB4 KIAA0558 MYSB	Homo sapiens (human)
Phenylalanine metabolism	Dihydropteridine reductase Isoaspartyl peptidase/L-asparaginase Kynurenine--oxoglutarate transaminase 1 L-amino-acid oxidase Phenylalanine-4-hydroxylase Pterin-4-alpha-carbinolamine dehydratase	P00439 P09417 P61457 Q16773 Q7L266 Q96RQ9	ALP ASRGL1 CCBL1 CRASH DCOH DHPR FIG1 IL4I1 KYAT1 PAH PCBD PCBD1 QDPR SDR33C1	Homo sapiens (human)

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