GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1376 - 1400** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
NTRK3 as a dependence receptor	Apoptosis regulator BAX NT-3 growth factor receptor Negative elongation factor B	Q07812 Q16288 Q8WX92	BAX BCL2L4 COBRA1 KIAA1182 NELFB NTRK3 TRKC	Homo sapiens (human)
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	Bridging integrator 2 Golgin subfamily A member 4 KN motif and ankyrin repeat domain-containing protein 1 Transcription factor ETV6 Vascular endothelial growth factor receptor 2	P35968 P41212 Q13439 Q14678 Q9UBW5	ANKRD15 BIN2 BRAP1 ETV6 FLK1 GOLGA4 KANK KANK1 KDR KIAA0172 TEL TEL1 VEGFR2	Homo sapiens (human)
TNFR2 non-canonical NF-kB pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 TNF receptor-associated factor 2 TNF receptor-associated factor 3 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 12 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor receptor superfamily member 11A Tumor necrosis factor receptor superfamily member 12A Tumor necrosis factor receptor superfamily member 13C Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 3 Tumor necrosis factor	O00231 O00232 O00487 O14788 O14818 O43242 O43508 O43557 P01374 P01375 P17980 P20333 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P29965 P35998 P36941 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 Q06643 Q12933 Q13114 Q13200 Q13489 Q13490 Q15008 Q16186 Q96RJ3 Q99436 Q99460 Q99558 Q9NP84 Q9UNM6 Q9Y275 Q9Y6Q6	ADRM1 API1 API2 APO3L BAFF BAFFR BIRC2 BIRC3 BLYS BR3 C7orf76 CAP-1 CD40L CD40LG CRAF1 D12S370 DR3LG DSS1 FN14 GP110 HC2 HC3 HC8 HC9 HSPC HVEML KIAA0107 LIGHT LMPX LMPY LTA LTB LTBR MAP3K14 MB1 MIHB MIHC MIP224 MOV34L MSS1 NIK NU OPGL PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RANK RANKL RNF48 RNF49 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TALL1 TBP1 TBP7 TNF TNFA TNFB TNFBR TNFC TNFCR TNFR2 TNFR3 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF1B TNFRSF3 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF2 TNFSF20 TNFSF3 TNFSF5 TRAF2 TRAF3 TRAFAMN TRANCE TRAP TRAP2 TRAP3 X Y Z ZTNF4	Homo sapiens (human)
Defective GALK1 causes GALCT2	Galactokinase	P51570	GALK GALK1	Homo sapiens (human)	G93924TT
Crosslinking of collagen fibrils	Bone morphogenetic protein 1 Lysyl oxidase homolog 1 Lysyl oxidase homolog 2 Lysyl oxidase homolog 3 Lysyl oxidase homolog 4 Peroxidasin homolog Procollagen C-endopeptidase enhancer 1 Protein-lysine 6-oxidase Tolloid-like protein 1 Tolloid-like protein 2	O43897 P13497 P28300 P58215 Q08397 Q15113 Q92626 Q96JB6 Q9Y4K0 Q9Y6L7	BMP1 KIAA0230 KIAA0932 LOX LOXC LOXL LOXL1 LOXL2 LOXL3 LOXL4 MG50 PCOLC PCOLCE PCPE1 PRG2 PXD01 PXDN TLL TLL1 TLL2 VPO VPO1	Homo sapiens (human)
STAT3 nuclear events downstream of ALK signaling	Cytokine receptor common subunit gamma DNA (cytosine-5)-methyltransferase 1 Histone acetyltransferase p300 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Hypoxia-inducible factor 1-alpha PR domain zinc finger protein 1 Paired amphipathic helix protein Sin3a Programmed cell death 1 ligand 1 Signal transducer and activator of transcription 3	O15379 O75626 P26358 P31785 P40763 Q09472 Q13547 Q16665 Q92769 Q96ST3 Q9NZQ7	AIM APRF B7H1 BHLHE78 BLIMP1 CD274 CXXC9 DNMT DNMT1 EP300 HDAC1 HDAC2 HDAC3 HIF1A IL2RG MOP1 P300 PASD8 PDCD1L1 PDCD1LG1 PDL1 PRDM1 RPD3L1 SIN3A STAT3	Homo sapiens (human)
Stimuli-sensing channels	Acid-sensing ion channel 1 Acid-sensing ion channel 2 Acid-sensing ion channel 3 Acid-sensing ion channel 4 Acid-sensing ion channel 5 Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit delta Amiloride-sensitive sodium channel subunit gamma Anoctamin-10 Anoctamin-1 Anoctamin-2 Anoctamin-3 Anoctamin-4 Anoctamin-5 Anoctamin-6 Anoctamin-7 Anoctamin-8 Anoctamin-9 Aspartyl/asparaginyl beta-hydroxylase Barttin Bestrophin-1 Bestrophin-2a Bestrophin-3 Bestrophin-4 Calcium-activated chloride channel regulator 1 Calcium-activated chloride channel regulator 2 Calcium-activated chloride channel regulator 4 Calcium-activated chloride channel regulator family member 3 Calmodulin-1 Chloride channel protein 1 Chloride channel protein 2 Chloride channel protein ClC-Ka Chloride channel protein ClC-Kb Chloride intracellular channel protein 2 E3 ubiquitin-protein ligase NEDD4-like H(+)/Cl(-) exchange transporter 3 H(+)/Cl(-) exchange transporter 4 H(+)/Cl(-) exchange transporter 5 H(+)/Cl(-) exchange transporter 6 H(+)/Cl(-) exchange transporter 7 NEDD4-like E3 ubiquitin-protein ligase WWP1 Osteopetrosis-associated transmembrane protein 1 Peptidyl-prolyl cis-trans isomerase FKBP1B Polyubiquitin-B Polyubiquitin-C Protein tweety homolog 2 Protein tweety homolog 3 Protein unc-79 homolog Protein unc-80 homolog RAF proto-oncogene serine/threonine-protein kinase Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase Sgk2 Serine/threonine-protein kinase Sgk3 Serine/threonine-protein kinase WNK1 Serine/threonine-protein kinase WNK2 Serine/threonine-protein kinase WNK3 Serine/threonine-protein kinase WNK4 Sodium leak channel NALCN Sodium-dependent phosphate transport protein 4 Sodium/hydrogen exchanger 11 Sodium/hydrogen exchanger 9B1 Sodium/hydrogen exchanger 9B2 Solute carrier family 9 member C1 Sorcin Stomatin-like protein 3 Stomatin TSC22 domain family protein 3 Triadin Two pore channel protein 1 Two pore channel protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A1A5B4 A8K7I4 O00141 O00476 O15247 O76090 P04049 P0CG47 P0CG48 P0DP23 P21817 P27105 P30626 P35523 P37088 P51168 P51170 P51172 P51788 P51790 P51793 P51795 P51797 P51798 P51800 P51801 P62979 P62987 P68106 P78348 Q12797 Q13061 Q14CN2 Q15413 Q16515 Q32M45 Q4G0N8 Q4KMQ2 Q4ZJI4 Q5TAH2 Q5XXA6 Q6IWH7 Q75V66 Q86UD5 Q86WC4 Q8IZF0 Q8N1M1 Q8N2C7 Q8NFU0 Q8NFU1 Q8NHX9 Q8TAV4 Q8WZ55 Q92736 Q96BR1 Q96FT7 Q96J92 Q96PU5 Q99576 Q9BSA4 Q9BYP7 Q9BYT9 Q9C0H2 Q9H0M0 Q9H4A3 Q9HBY8 Q9HCE9 Q9NQ90 Q9NW15 Q9NY37 Q9P2D8 Q9UHC3 Q9ULQ1 Q9UQC9 Q9Y3S1 Q9Y6N3	ACCN ACCN1 ACCN2 ACCN3 ACCN4 ACCN5 ANO1 ANO10 ANO2 ANO3 ANO4 ANO5 ANO6 ANO7 ANO8 ANO9 ASIC1 ASIC2 ASIC3 ASIC4 ASIC5 ASPH BAH BART BEST1 BEST2 BEST3 BEST4 BNAC1 BNAC2 BND7 BSND C11orf25 C12orf3 C17orf29 C2orf21 CACC1 CACC3 CALM CALM1 CAM CAM1 CISK CLC1 CLCA1 CLCA2 CLCA3 CLCA3P CLCA4 CLCK2 CLCN1 CLCN2 CLCN3 CLCN4 CLCN5 CLCN6 CLCN7 CLCNKA CLCNKB CLIC2 CaCC2 DNACH DOG1 DSIPI EPB72 FKBP12.6 FKBP1B FKBP1L FKBP9 GDD1 GILZ GL HBRR HINAC HSN2 KDP KIAA0046 KIAA0344 KIAA0439 KIAA1169 KIAA1409 KIAA1566 KIAA1623 KIAA1691 KIAA1760 KIAA1843 MDEG NALCN NEDD4L NEDL3 NGEP NHA1 NHA2 NHEDC1 NHEDC2 NPT4 ORAOV2 OSTM1 OTK4 PCANAP5 PIG5 PRKWNK1 PRKWNK2 PRKWNK3 PRKWNK4 RAF RAF1 RPS27A RYDR RYR1 RYR2 RYR3 SCNN1 SCNN1A SCNN1B SCNN1D SCNN1G SDCCAG43 SGK SGK1 SGK2 SGK3 SGKL SLC17A3 SLC9A10 SLC9A11 SLC9B1 SLC9B2 SLC9C1 SLC9C2 SLNAC1 SRI STOM STOML3 TAOS2 TMEM16A TMEM16B TMEM16C TMEM16D TMEM16E TMEM16F TMEM16G TMEM16H TMEM16J TMEM16K TNAC1 TP53I5 TPC1 TPC2 TPCN1 TPCN2 TRDN TSC22D3 TTYH2 TTYH3 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UNC79 UNC80 VGCNL1 VMD2 VMD2L1 VMD2L2 VMD2L3 WNK1 WNK2 WNK3 WNK4 WWP1	Homo sapiens (human)
Endogenous sterols	24-hydroxycholesterol 7-alpha-hydroxylase Adrenodoxin, mitochondrial Aromatase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Bile acid receptor Cholesterol 24-hydroxylase Cholesterol side-chain cleavage enzyme, mitochondrial Cytochrome P450 11B1, mitochondrial Cytochrome P450 11B2, mitochondrial Cytochrome P450 1B1 Cytochrome P450 4V2 Cytochrome P450 7A1 Cytochrome P450 7B1 Ferredoxin-2, mitochondrial Lanosterol 14-alpha demethylase NADPH Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Pro-opiomelanocortin Retinoic acid receptor RXR-alpha Steroid 21-hydroxylase Sterol 26-hydroxylase, mitochondrial	A9YTQ3 O75881 P01189 P05108 P08686 P10109 P11511 P15538 P19099 P19793 P22570 P22680 P27540 P35869 Q02318 Q15596 Q15788 Q16678 Q16850 Q6P4F2 Q6ZWL3 Q96RI1 Q9HBZ2 Q9NYL5 Q9Y6A2	ADX ADXR AHR AHRR ARNT ARNT2 ARO1 BAR BHLHE1 BHLHE2 BHLHE74 BHLHE75 BHLHE76 BHLHE77 CYAR CYP11A CYP11A1 CYP11B1 CYP11B2 CYP19 CYP19A1 CYP1B1 CYP21 CYP21A2 CYP21B CYP27 CYP27A1 CYP39A1 CYP46 CYP46A1 CYP4V2 CYP51 CYP51A1 CYP7 CYP7A1 CYP7B1 FDX1 FDX1L FDX2 FDXR FXR HRR1 KIAA0307 KIAA1234 NCOA1 NCOA2 NR1H4 NR2B1 POMC RIP14 RXRA S11BH SRC1 SRC2 TIF2	Homo sapiens (human)
Mitochondrial ABC transporters	ATP-binding cassette sub-family B member 10, mitochondrial ATP-binding cassette sub-family B member 6 Iron-sulfur clusters transporter ABCB7, mitochondrial Mitochondrial potassium channel ATP-binding subunit	O75027 Q9NP58 Q9NRK6 Q9NUT2	ABC7 ABCB10 ABCB6 ABCB7 ABCB8 MABC1 MITOSUR MTABC3 PRP UMAT	Homo sapiens (human)
Masitinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Defective visual phototransduction due to STRA6 loss of function	Receptor for retinol uptake STRA6 Retinol-binding protein 4 Transthyretin	P02753 P02766 Q9BX79	PALB RBP4 STRA6 TTR	Homo sapiens (human)
Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR)	Solute carrier organic anion transporter family member 1B1	Q9Y6L6	LST1 OATP1B1 OATP2 OATPC SLC21A6 SLCO1B1	Homo sapiens (human)
APC/C:Cdc20 mediated degradation of mitotic proteins	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 O43684 O60566 P30260 P51668 P51965 P60006 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L SFT SSK1 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Variant SLC6A14 may confer susceptibility towards obesity	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)	Q9UN76	SLC6A14	Homo sapiens (human)
TNFR1-mediated ceramide production	Protein FAN Small ribosomal subunit protein RACK1 Sphingomyelin phosphodiesterase 2 Sphingomyelin phosphodiesterase 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor	O60906 P01375 P19438 P63244 Q92636 Q9NY59	FAN GNB2L1 NSMAF RACK1 SMPD2 SMPD3 TNF TNFA TNFAR TNFR1 TNFRSF1A TNFSF2	Homo sapiens (human)
p130Cas linkage to MAPK signaling for integrins	Adapter molecule crk Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Breast cancer anti-estrogen resistance protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1A Ras-related protein Rap-1b Talin-1 von Willebrand factor	P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P46108 P56945 P61224 P62834 Q05397 Q7Z5R6 Q9Y490	APBB1IP BCAR1 CAS CASS1 CRK CRKAS F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 PREL1 PTK2 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VWF	Homo sapiens (human)
SHC1 events in ERBB2 signaling	Epidermal growth factor receptor GTPase HRas GTPase NRas Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein kinase C alpha type Protein kinase C delta type Protein kinase C epsilon type Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 12	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P17252 P29353 P35070 P56975 Q02156 Q02297 Q05209 Q05655 Q07889 Q8WWG1 Q99075	BTC DTR DTS EGF EGFR ERBB ERBB1 ERBB2 EREG GGF HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PKCA PKCD PKCE PRKACA PRKCA PRKCD PRKCE PTPN12 SHC SHC1 SHCA SMDF SOS1	Homo sapiens (human)
IKBKB deficiency causes SCID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16	Homo sapiens (human)
Toxicity of botulinum toxin type B (botB)	Botulinum neurotoxin type B HA-17 HA-33 protein Ha70 protein NTNHA Synaptotagmin-1 Synaptotagmin-2 Vesicle-associated membrane protein 2	P10844 P21579 P63027 Q45877 Q45878 Q57230 Q8N9I0 Q9LBS8	HA HA-17 HA-33 SVP65 SYB2 SYT SYT1 SYT2 VAMP2 botB ha17 ha34 ha70 ntnha	Homo sapiens (human)
Collagen chain trimerization	Collagen alpha-1(I) chain Collagen alpha-1(II) chain Collagen alpha-1(III) chain Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(V) chain Collagen alpha-1(VI) chain Collagen alpha-1(VII) chain Collagen alpha-1(VIII) chain Collagen alpha-1(X) chain Collagen alpha-1(XI) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XX) chain Collagen alpha-1(XXI) chain Collagen alpha-1(XXII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXIV) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-1(XXVII) chain Collagen alpha-1(XXVIII) chain Collagen alpha-2(I) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-2(V) chain Collagen alpha-2(VI) chain Collagen alpha-2(VIII) chain Collagen alpha-2(XI) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-3(V) chain Collagen alpha-3(VI) chain Collagen alpha-4(IV) chain Collagen alpha-5(IV) chain Collagen alpha-5(VI) chain Collagen alpha-6(IV) chain Collagen alpha-6(VI) chain	A6NMZ7 A8TX70 P02452 P02458 P02461 P02462 P05997 P08123 P08572 P12107 P12109 P12110 P12111 P13942 P20849 P20908 P25067 P25940 P27658 P29400 P39059 P39060 P53420 Q01955 Q02388 Q03692 Q05707 Q07092 Q14031 Q14050 Q14055 Q14993 Q17RW2 Q2UY09 Q5TAT6 Q86Y22 Q8IZC6 Q8NFW1 Q96A83 Q96P44 Q99715 Q9BXS0 Q9P218 Q9UMD9	BP180 BPAG2 C3orf7 COL10A1 COL11A1 COL11A2 COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL1A1 COL1A2 COL1AL COL20A1 COL21A1 COL22A1 COL23A1 COL24A1 COL25A1 COL26A1 COL27A1 COL28 COL28A1 COL29A1 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL7A1 COL8A1 COL8A2 COL9A1 COL9A2 COL9A3 COLL6 EMID2 EMU2 KIAA1510 KIAA1870 UND VWA4	Homo sapiens (human)
Regulation of RUNX3 expression and activity	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Core-binding factor subunit beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Histone acetyltransferase p300 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proto-oncogene tyrosine-protein kinase Src Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 P01137 P0CG47 P0CG48 P12931 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q00987 Q09472 Q13200 Q13761 Q13951 Q15008 Q16186 Q8N726 Q99436 Q99460 Q9HAU4 Q9HCE7 Q9UNM6	ADRM1 AML2 C7orf76 CBFA3 CBFB CDKN2 CDKN2A DSS1 EP300 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 KIAA1625 LMPX LMPY MB1 MDM2 MIP224 MLM MOV34L MSS1 NU P300 PEBP2A3 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A RUNX3 SEM1 SHFDG1 SHFM1 SMURF1 SMURF2 SRC SRC1 SUG1 SUG2 TBP1 TBP7 TGFB TGFB1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
Downregulation of ERBB2 signaling	Cullin-5 E3 ubiquitin-protein ligase CHIP Epidermal growth factor receptor Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Megakaryocyte-associated tyrosine-protein kinase Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type 18 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14511 O14944 P00533 P01133 P04626 P07900 P0CG47 P0CG48 P35070 P42679 P56975 P62979 P62987 Q02297 Q05209 Q16543 Q8WWG1 Q93034 Q96RT1 Q99075 Q99952 Q9UNE7	BDP1 BTC CDC37 CDC37A CHIP CTK CUL5 DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG GGF HBEGF HEGFL HER1 HER2 HGL HRGA HSP90A HSP90AA1 HSPC1 HSPCA HYL KIAA1225 LAP2 MATK MLN19 NDF NEU NGL NRG1 NRG2 NRG3 NRG4 NTAK PTPN12 PTPN18 RPS27A SMDF STUB1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VACM1	Homo sapiens (human)
UCH proteinases	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Actin, cytoplasmic 1 Actin-like protein 6A Actin-related protein 5 Actin-related protein 8 BRCA1-associated RING domain protein 1 Chromatin-remodeling ATPase INO80 Forkhead box protein K1 Forkhead box protein K2 Histone H2A type 1-A Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-H Histone H2A type 1-J Histone H2A type 1 Histone H2A type 2-A Histone H2A type 2-B Histone H2A type 2-C Histone H2A type 3 Host cell factor 1 INO80 complex subunit B INO80 complex subunit C INO80 complex subunit D INO80 complex subunit E Lysine-specific histone demethylase 2 Methyl-CpG-binding domain protein 5 Methyl-CpG-binding domain protein 6 Microspherule protein 1 Mothers against decapentaplegic homolog 7 NEDD8 Nuclear factor related to kappa-B-binding protein Polycomb group protein ASXL1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Putative Polycomb group protein ASXL2 RuvB-like 1 Sentrin-specific protease 8 TCF3 fusion partner TGF-beta receptor type-1 TGF-beta receptor type-2 Transcriptional repressor protein YY1 Transforming growth factor beta-1 proprotein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase BAP1 Ubiquitin carboxyl-terminal hydrolase isozyme L1 Ubiquitin carboxyl-terminal hydrolase isozyme L3 Ubiquitin carboxyl-terminal hydrolase isozyme L5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O15105 O15294 O43242 O96019 P01137 P04908 P09936 P0C0S8 P0C1Z6 P0CG47 P0CG48 P15374 P17980 P20618 P20671 P25490 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P36897 P37173 P43686 P48556 P49720 P49721 P51610 P51665 P60709 P60896 P60900 P62191 P62195 P62333 P62979 P62987 P85037 Q01167 Q13200 Q15008 Q15843 Q16186 Q16777 Q53TQ3 Q6FI13 Q6P4R8 Q6PI98 Q76L83 Q7L7L0 Q8IUE6 Q8IXJ9 Q8NB78 Q8NBZ0 Q92560 Q93077 Q96DN6 Q96EZ8 Q96KK5 Q96LD8 Q96QV6 Q99436 Q99460 Q99728 Q99878 Q9C086 Q9H981 Q9H9F9 Q9P267 Q9ULG1 Q9UNM6 Q9Y265 Q9Y4E8 Q9Y5K5	ACTB ACTL6A ACTR5 ACTR8 ADRM1 ALK5 AOF1 ARP5 ARP8 ASXH2 ASXL1 ASXL2 BAF53 BAF53A BAP1 BARD1 C18orf37 C6orf193 C7orf76 CCDC95 DEN1 DSS1 FOXK1 FOXK2 GP110 H2AC1 H2AC11 H2AC12 H2AC13 H2AC14 H2AC15 H2AC16 H2AC17 H2AC18 H2AC19 H2AC20 H2AC21 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFC H2AFD H2AFE H2AFG H2AFI H2AFL H2AFM H2AFN H2AFO H2AFP H2AFQ H2AFR H2AW HC2 HC3 HC8 HC9 HCF1 HCFC1 HFC1 HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST3H2A HMGA1L4 HSPC ILF ILF1 INO80 INO80A INO80B INO80C INO80D INO80E INO80F INO80G INO80H INO80K INO80N INO80Q INO80S INOC1 KDM1B KIAA0107 KIAA0272 KIAA0529 KIAA0978 KIAA1259 KIAA1461 KIAA1685 KIAA1887 LMPX LMPY LSD2 MADH7 MADH8 MB1 MBD5 MBD6 MCRS1 MIP224 MNF MOV34L MSP58 MSS1 NEDD8 NEDP1 NFRKB NMP238 NU OGT PAPA1 PFAAP4 POH1 PROS26 PROS27 PROS30 PRSC2 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A RUVBL1 SEM1 SENP8 SHFDG1 SHFM1 SKR4 SMAD7 SUG1 SUG2 TBP1 TBP7 TFPT TGFB TGFB1 TGFBR1 TGFBR2 TIP49 TIP49A TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCH37 UCHL1 UCHL3 UCHL5 USP15 X Y YY1 Z ZNHIT4	Homo sapiens (human)
Defective regulation of TLR7 by endogenous ligand	Toll-like receptor 7	Q9NYK1	TLR7	Homo sapiens (human)
Regulation of pyruvate metabolism	Armadillo repeat-containing protein 8 E3 ubiquitin-protein transferase MAEA E3 ubiquitin-protein transferase RMND5A E3 ubiquitin-protein transferase RMND5B Glucose-induced degradation protein 4 homolog Glucose-induced degradation protein 8 homolog L-lactate dehydrogenase A chain Muskelin NADP-dependent malic enzyme Polyubiquitin-B Polyubiquitin-C Ran-binding protein 9 Serine/threonine-protein kinase Nek1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 26	P00338 P0CG47 P0CG48 P48163 P62979 P62987 Q7L5Y9 Q8IUR7 Q8IVV7 Q96G75 Q96PY6 Q96S59 Q9H7D7 Q9H871 Q9NWU2 Q9UL63	ARMC8 C17orf39 C20orf11 CDW2 EMP GID4 GID8 KIAA1901 LDHA MAEA ME1 MIP2 MKLN1 NEK1 RANBP9 RANBPM RMND5A RMND5B RPS27A TWA1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VID24 WDR26	Homo sapiens (human)

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