Degradation of GABA
|
|
|
|
|
Degradation of GLI1 by the proteasome
|
|
|
- Cul1
- Gli
- Gli1
- Itch
- Kiaa0072
- Kiaa0077
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Numb
- P91a
- Pa28b1
- Pad1
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Skp1
- Skp1a
- Sufu
- Sug1
- Sug2
- Tbp1
- Tbp7
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Degradation of beta-catenin by the destruction complex
|
|
|
- Amer1
- Apc
- Axin
- Axin1
- Catnb
- Csnk1a1
- Ctnnb1
- Cul1
- Fam123b
- Fu
- Gsk3b
- Kiaa0072
- Kiaa0077
- Kiaa4006
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Mc13
- Mcb1
- Mecl1
- Mmc14
- Mov-34
- Mov34
- Mss1
- P91a
- Pa28b1
- Pad1
- Ppp2ca
- Ppp2cb
- Ppp2r1a
- Ppp2r1b
- Ppp2r5a
- Ppp2r5b
- Ppp2r5c
- Ppp2r5d
- Ppp2r5e
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Rbx1
- Ring12
- Rps27a
- Skp1
- Skp1a
- Sug1
- Sug2
- Tbp1
- Tbp7
- Trabid
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Zranb1
|
|
Degradation of cysteine and homocysteine
|
|
|
- Ado
- Cdo1
- Cth
- Fmo-1
- Fmo1
- Gadl1
- Gm237
- Mpst
- Tst
- Txn2
|
|
Degradation of the extracellular matrix
|
|
|
- A2m
- A2mp
- Acan
- Adam10
- Adam15
- Adam8
- Adamts4
- Adamts5
- Agc
- Agc1
- Bcan
- Bsg
- Canp1
- Capa1
- Capa6
- Capn1
- Capn10
- Capn11
- Capn12
- Capn13
- Capn15
- Capn2
- Capn3
- Capn4
- Capn5
- Capn6
- Capn7
- Capn8
- Capn9
- Capns1
- Capns2
- Cast
- Cats
- Cd44
- Cdh1
- Clg4b
- Ctsg
- Ctsk
- Ctsl
- Ctsl1
- Ctss
- Dcn
- Ela2
- Elane
- Ent
- Eta-1
- Gm943
- Htra
- Htra1
- Klk7
- Kuz
- Ly-24
- Madm
- McolA
- Mdc15
- Mme
- Mmel
- Mmp10
- Mmp11
- Mmp12
- Mmp13
- Mmp14
- Mmp19
- Mmp1a
- Mmp2
- Mmp20
- Mmp3
- Mmp7
- Mmp8
- Mmp9
- Ms2
- Mtmmp
- Ncl2
- Ncl3
- Ncl4
- Nid1
- Op
- Opt
- Optc
- Palbh
- Prss11
- Prss6
- Rasi
- Scce
- Scube1
- Scube3
- Solh
- Spp-1
- Spp1
- Tmprss6
|
|
Depolymerization of the Nuclear Lamina
|
|
|
- Caper
- Ccn-2
- Ccnb1
- Ccnb1-rs13
- Cdc2
- Cdc2a
- Cdk1
- Cdkn1
- Cnep1r1
- Ctdnep1
- Cycb
- Cycb1
- Dullard
- Emd
- Flde
- Lmn1
- Lmna
- Lmnb1
- Lpin1
- Lpin2
- Lpin3
- Pkca
- Pkcb
- Prkca
- Prkcb
- Prkcb1
- Rbm39
- Rnpc2
- Sta
- Tmem188
|
|
Deposition of new CENPA-containing nucleosomes at the centromere
|
|
|
- Apitd1
- Cenpa
- Cenpc
- Cenpc1
- Cenph
- Cenpi
- Cenpk
- Cenpl
- Cenpm
- Cenpn
- Cenpo
- Cenpp
- Cenpq
- Cenpr
- Cenps
- Cenpt
- Cenpu
- Cenpw
- Cenpx
- Cug2
- Enp
- FAAP16
- Faap10
- Fleg1
- Fshprh1
- Gm14920
- H2a.x
- H2ab1
- H2ab2
- H2ab3
- H2ac11
- H2ac12
- H2ac13
- H2ac15
- H2ac20
- H2ac4
- H2ac6
- H2ac8
- H2afv
- H2afx
- H2aj
- H2av
- H2ax
- H2az2
- H2b-f
- H2b-j
- H2b-l
- H2b-n
- H2bc1
- H2bc11
- H2bc12
- H2bc13
- H2bc14
- H2bc15
- H2bc21
- H2bc26
- H2bc26-ps
- H2bc3
- H2bc4
- H2bc6
- H2bc7
- H2bc8
- H2bc9
- H2bu1
- H2bu1-ps
- H4-12
- H4-53
- H4c1
- H4c11
- H4c12
- H4c14
- H4c16
- H4c2
- H4c3
- H4c4
- H4c6
- H4c8
- H4c9
- H4f16
- Hist1h2ab
- Hist1h2ac
- Hist1h2ae
- Hist1h2af
- Hist1h2ag
- Hist1h2ah
- Hist1h2ai
- Hist1h2ak
- Hist1h2an
- Hist1h2ao
- Hist1h2ap
- Hist1h2ba
- Hist1h2bb
- Hist1h2bc
- Hist1h2be
- Hist1h2bf
- Hist1h2bg
- Hist1h2bh
- Hist1h2bj
- Hist1h2bk
- Hist1h2bl
- Hist1h2bm
- Hist1h2bn
- Hist1h2bp
- Hist1h4a
- Hist1h4b
- Hist1h4c
- Hist1h4d
- Hist1h4f
- Hist1h4h
- Hist1h4i
- Hist1h4j
- Hist1h4k
- Hist1h4m
- Hist2h2aa1
- Hist2h2aa2
- Hist2h2ab
- Hist2h2ac
- Hist2h2be
- Hist2h4
- Hist2h4a
- Hist3h2bb
- Hist3h2bb-ps
- Hist4h4
- Hist5-2ax
- Hjurp
- Itgb3bp
- Kiaa1903
- Knl2
- M18bp1
- MHF1
- Mcm21r
- Mhf2
- Mis18a
- Mis18bp1
- Mlf1ip
- Ms18b
- Npm1
- Nrif3
- Oip5
- Pane1
- Rbap46
- Rbap48
- Rbbp4
- Rbbp7
- Rsf1
- Ruvbl1
- Smarca5
- Snf2h
- Solt
- Stra13
- Th2b
- Tip49
- Tip49a
|
|
Dermatan sulfate biosynthesis
|
|
|
- An2
- Bcan
- Bgn
- Caleb
- Chst14
- Cspg2
- Cspg3
- Cspg4
- Cspg5
- D4st1
- Dcn
- Dse
- Dsel
- Kiaa4232
- Ncan
- Ng2
- Ngc
- Sart2
- Ust
- Vcan
|
|
Detoxification of Reactive Oxygen Species
|
|
|
- Aop1
- Aop2
- Apah1
- Cas-1
- Cas1
- Cat
- Ccs
- Ccsd
- Cgd
- Cyba
- Cybb
- Cycs
- Ero1a
- Ero1l
- Gpx1
- Gpx2
- Gpx3
- Gpx5
- Gpx6
- Gpx7
- Gpx8
- Gr1
- Gsr
- Gstp1
- Gstp2
- Gstpia
- Gstpib
- Ltw4
- Mer5
- Msp23
- Ncf1
- Ncf2
- Ncf4
- Nox4
- Noxa2
- Nudt2
- P4hb
- P67phox
- Paga
- Pdia1
- Prdx1
- Prdx2
- Prdx3
- Prdx5
- Prdx6
- Renox
- Sod-2
- Sod1
- Sod2
- Sod3
- Tdpx1
- Tdpx2
- Tpx
- Trxr1
- Trxr2
- Txn
- Txn1
- Txn2
- Txnrd1
- Txnrd2
|
|
Digestion
|
|
|
- Alpi
- Guc2c
- Guca2
- Guca2a
- Guca2b
- Gucy2c
- Pir
|
|
Digestion of dietary carbohydrate
|
|
|
- Amy2
- Amy2a
- Amy2a5
- Chia
- Chia1
- Chit1
- Lct
- Mgam
- Sis
|
|
Digestion of dietary lipid
|
|
|
- Cel
- Clps
- Lip1
- Lipf
- Plrp2
- Pnlip
- Pnliprp1
- Pnliprp2
|
|
Dimerization of procaspase-8
|
|
|
- Apt1
- Apt1lg1
- Cash
- Casp8
- Cd95l
- Cflar
- Dr5
- Fadd
- Fas
- Fasl
- Faslg
- Killer
- Mort1
- Rinp
- Rip
- Ripk1
- Tnfrsf10b
- Tnfrsf6
- Tnfsf10
- Tnfsf6
- Tradd
- Traf2
- Trail
- gld
|
|
Disassembly of the destruction complex and recruitment of AXIN to the membrane
|
|
|
- Amer1
- Apc
- Axin
- Axin1
- Catnb
- Cav
- Cav1
- Csnk1a1
- Ctnnb1
- Dvl
- Dvl1
- Dvl2
- Dvl3
- Fam123b
- Frat1
- Frat2
- Fu
- Fzd1
- Fzd10
- Fzd2
- Fzd5
- Gsk3b
- Int-1
- Kiaa4006
- Lr3
- Lrp5
- Lrp6
- Lrp7
- Ppp2ca
- Ppp2cb
- Ppp2r1a
- Ppp2r1b
- Ppp2r5a
- Ppp2r5b
- Ppp2r5c
- Ppp2r5d
- Ppp2r5e
- Stra11
- Wnt-1
- Wnt-3a
- Wnt1
- Wnt3a
- Wnt8a
- Wnt8b
- Wnt8d
|
|
Disinhibition of SNARE formation
|
|
|
- Pkca
- Pkcb
- Pkcc
- Pkcg
- Prkca
- Prkcb
- Prkcb1
- Prkcc
- Prkcg
- Stx4
- Stx4a
- Stxbp3
- Stxbp3a
- Unc18c
|
|
Displacement of DNA glycosylase by APEX1
|
|
|
- Ape
- Apex
- Apex1
- Mbd4
- Mid1
- Mpg
- Mutyh
- Myh
- Nth1
- Nthl1
- Ogg1
- Ref1
- Smug1
- Tdg
- Ung
- Ung1
|
|
Dissolution of Fibrin Clot
|
|
|
- Anx2
- Anxa2
- Cal1h
- Cal1l
- Hrg
- Mr1
- Pai1
- Pai2
- Pi7
- Planh1
- Planh2
- Plat
- Plau
- Plaur
- Plg
- Pli
- Pn1
- S100a10
- Serpinb2
- Serpinb6
- Serpinb6a
- Serpinb8
- Serpine1
- Serpine2
- Serpinf2
- Spi3
- Spi4
|
|
Dopamine Neurotransmitter Release Cycle
|
|
|
- Apba1
- Bzrap1
- Cask
- Cplx1
- Kiaa0340
- Kiaa0612
- Lin-2
- Lin7a
- Lin7b
- Lin7c
- Mals1
- Mals2
- Mals3
- Mint1
- Ppfia1
- Ppfia2
- Ppfia3
- Ppfia4
- Rab3a
- Rab3ip1
- Rbp1
- Rim1
- Rims1
- Slc18a2
- Snap
- Snap25
- Stx1a
- Stxbp1
- Syb2
- Syn-1
- Syn1
- Syn2
- Syn3
- Syt1
- Tspoap1
- Unc13a
- Unc13b
- Vamp2
- Veli1
- Veli2
- Veli3
- Vmat2
- X11
- mLin-10
- ppfia4
|
|
Dopamine receptors
|
|
|
- Drd1
- Drd1a
- Drd2
- Drd3
- Drd4
- Drd5
- Gpcr15
|
|
Downregulation of ERBB2 signaling
|
|
|
- Bcn
- Btc
- Cdc37
- Chip
- Ctk
- Cul5
- Dtr
- Egf
- Egfr
- Erbb2
- Erbb2ip
- Erbb3
- Erbb4
- Erbin
- Ereg
- Flp1
- Hbegf
- Hegfl
- Hsp86
- Hsp86-1
- Hsp90aa1
- Hspca
- Kiaa1225
- Kiaa3023
- Lap2
- Matk
- Mer4
- Neu
- Nrg1
- Nrg2
- Nrg3
- Ntk
- Ptpk1
- Ptpn12
- Ptpn18
- Rps27a
- Stub1
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
Downregulation of ERBB2:ERBB3 signaling
|
|
|
- Akt
- Akt1
- Akt2
- Akt3
- Erbb2
- Erbb3
- Flrf
- Kiaa0055
- Kiaa3023
- Neu
- Nrdp1
- Nrg1
- Nrg2
- Rac
- Rnf41
- Rps27a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Ubpy
- Usp8
|
|
Downregulation of ERBB4 signaling
|
|
|
- Erbb4
- Itch
- Kiaa0093
- Mer4
- Nedd-4
- Nedd4
- Nedd4-1
- Nedd4a
- Rpf1
- Rps27a
- Src
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Wwp1
|
|
Downregulation of SMAD2/3:SMAD4 transcriptional activity
|
|
|
- Adprp
- Adprt
- Adprt1
- Atp1b4
- Dpc4
- Erk1
- Erk2
- Fafl
- Fam
- Hdac1
- Kiaa0439
- Kiaa1113
- Madh2
- Madh3
- Madh4
- Madr2
- Mapk
- Mapk1
- Mapk3
- Ncor1
- Ncor2
- Nedd4b
- Nedd4l
- Parp1
- Ppm1a
- Pppm1a
- Prkm1
- Prkm3
- Rps27a
- Rxrip13
- Ski
- Skiip
- Skil
- Skir
- Smad2
- Smad3
- Smad4
- Smrt
- Smurf2
- Sno
- Snw1
- Tgif
- Tgif1
- Tgif2
- Trim33
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Ube2d1
- Ube2d3
- Usp9x
|
|
Downregulation of TGF-beta receptor signaling
|
|
|
- Bambi
- Chip
- Madh2
- Madh3
- Madh7
- Madh8
- Madr2
- Mtmr4
- N4wbp4
- Nma
- Pmepa1
- Rps27a
- Smad2
- Smad3
- Smad7
- Smurf2
- Strap
- Stub1
- Tgfb1
- Tgfbr1
- Tgfbr2
- Tmepai
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
- Unrip
|
|
Downstream TCR signaling
|
- 26S proteasome non-ATPase regulatory subunit 10
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome non-ATPase regulatory subunit 12
- 26S proteasome non-ATPase regulatory subunit 13
- 26S proteasome non-ATPase regulatory subunit 14
- 26S proteasome non-ATPase regulatory subunit 1
- 26S proteasome non-ATPase regulatory subunit 2
- 26S proteasome non-ATPase regulatory subunit 3
- 26S proteasome non-ATPase regulatory subunit 4
- 26S proteasome non-ATPase regulatory subunit 5
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome non-ATPase regulatory subunit 7
- 26S proteasome non-ATPase regulatory subunit 8
- 26S proteasome non-ATPase regulatory subunit 9
- 26S proteasome regulatory subunit 10B
- 26S proteasome regulatory subunit 4
- 26S proteasome regulatory subunit 6A
- 26S proteasome regulatory subunit 6B
- 26S proteasome regulatory subunit 7
- 26S proteasome regulatory subunit 8
- 3-phosphoinositide-dependent protein kinase 1
- B-cell lymphoma/leukemia 10
- Caspase recruitment domain-containing protein 11
- Cullin-1
- F-box/WD repeat-containing protein 11
- H-2 class II histocompatibility antigen, A-D beta chain
- H-2 class II histocompatibility antigen, A-K alpha chain
- H-2 class II histocompatibility antigen, E-B beta chain
- H-2 class II histocompatibility antigen, E-D alpha chain
- Histocompatibility 2, class II antigen E beta2
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Mitogen-activated protein kinase kinase kinase 7
- Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog
- NF-kappa-B essential modulator
- NF-kappa-B inhibitor alpha
- Nuclear factor NF-kappa-B p105 subunit
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
- Phosphatidylinositol 3-kinase regulatory subunit alpha
- Phosphatidylinositol 3-kinase regulatory subunit beta
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
- Polyubiquitin-B
- Polyubiquitin-C
- Proteasome activator complex subunit 1
- Proteasome activator complex subunit 2
- Proteasome activator complex subunit 3
- Proteasome activator complex subunit 4
- Proteasome inhibitor PI31 subunit
- Proteasome subunit alpha type-1
- Proteasome subunit alpha type-2
- Proteasome subunit alpha type-3
- Proteasome subunit alpha type-4
- Proteasome subunit alpha type-5
- Proteasome subunit alpha type-6
- Proteasome subunit alpha type-7
- Proteasome subunit alpha type-8
- Proteasome subunit beta type-10
- Proteasome subunit beta type-11
- Proteasome subunit beta type-1
- Proteasome subunit beta type-2
- Proteasome subunit beta type-3
- Proteasome subunit beta type-4
- Proteasome subunit beta type-5
- Proteasome subunit beta type-6
- Proteasome subunit beta type-7
- Proteasome subunit beta type-8
- Proteasome subunit beta type-9
- Protein kinase C theta type
- Proto-oncogene tyrosine-protein kinase LCK
- Receptor-interacting serine/threonine-protein kinase 2
- S-phase kinase-associated protein 1
- T cell receptor alpha variable 16 (Fragment)
- T cell receptor alpha variable 19 (Fragment)
- T cell receptor beta, variable 15 (Fragment)
- T cell receptor beta, variable 16 (Fragment)
- T-cell receptor-associated transmembrane adapter 1
- T-cell surface glycoprotein CD3 delta chain
- T-cell surface glycoprotein CD3 epsilon chain
- T-cell surface glycoprotein CD3 gamma chain
- T-cell surface glycoprotein CD3 zeta chain
- T-cell surface glycoprotein CD4
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- TNF receptor-associated factor 6
- Transcription factor p65
- Ubiquitin-conjugating enzyme E2 D1
- Ubiquitin-conjugating enzyme E2 D2
- Ubiquitin-conjugating enzyme E2 N
- Ubiquitin-conjugating enzyme E2 R1
- Ubiquitin-conjugating enzyme E2 variant 1
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
|
|
- 7a33
- Bcl10
- Blu
- Btrcp2
- Card11
- Carma1
- Cd247
- Cd3d
- Cd3e
- Cd3g
- Cd3z
- Cd4
- Cdc34
- Chuk
- Ciper
- Clap
- Croc1
- Cul1
- Fbw1b
- Fbxw11
- Fbxw1b
- H2-Aa
- H2-Ab1
- H2-Ea
- H2-Eb1
- H2-Eb2
- Ikba
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Inpp5d
- Kiaa0072
- Kiaa0077
- Kiaa0733
- Lck
- Lmp10
- Lmp19
- Lmp2
- Lmp3
- Lmp7
- Lmpc3
- Lsk-t
- Malt1
- Map3k7
- Map3k7ip2
- Mc13
- Mcb1
- Mecl1
- Mmac1
- Mmc14
- Mov-34
- Mov34
- Mss1
- Nemo
- Nfkb1
- Nfkb3
- Nfkbia
- P91a
- Pa28b1
- Pad1
- Pdk1
- Pdpk1
- Pik3ca
- Pik3cb
- Pik3r1
- Pik3r2
- Pkcq
- Prkcq
- Psma1
- Psma2
- Psma3
- Psma4
- Psma5
- Psma6
- Psma7
- Psma7l
- Psma8
- Psmb1
- Psmb10
- Psmb11
- Psmb2
- Psmb3
- Psmb4
- Psmb5
- Psmb6
- Psmb7
- Psmb8
- Psmb9
- Psmc1
- Psmc2
- Psmc3
- Psmc4
- Psmc5
- Psmc6
- Psmd1
- Psmd10
- Psmd11
- Psmd12
- Psmd13
- Psmd14
- Psmd2
- Psmd3
- Psmd4
- Psmd5
- Psmd6
- Psmd7
- Psmd8
- Psmd9
- Psme1
- Psme2
- Psme3
- Psme4
- Psmf1
- Pten
- Rela
- Ring12
- Rip2
- Ripk2
- Rps27a
- Ship
- Ship1
- Skp1
- Skp1a
- Sug1
- Sug2
- T3d
- Tab2
- Tak1
- Tbp1
- Tbp7
- Tcrz
- Traf6
- Trat1
- Trav16
- Trav19
- Trbv15
- Trbv16
- Tstap91a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc4
- Ubcep1
- Ubcep2
- Ubch3
- Ubch4
- Ubch5b
- Ube2d1
- Ube2d2
- Ube2d2a
- Ube2n
- Ube2r1
- Ube2v1
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