TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
|
|
|
- Baff
- Baffr
- Bcmd
- Birc2
- Birc3
- Br3
- Cap-1
- Cd40
- Cd40l
- Cd40lg
- Craf1
- Fgfrp2
- Fn14
- Light
- Lta
- Ltb
- Ltbr
- Map3k14
- Nik
- Opgl
- Rank
- Rankl
- Tnfb
- Tnfc
- Tnfcr
- Tnfrsf11a
- Tnfrsf12a
- Tnfrsf13c
- Tnfrsf3
- Tnfrsf5
- Tnfsf1
- Tnfsf11
- Tnfsf12
- Tnfsf13b
- Tnfsf14
- Tnfsf3
- Tnfsf5
- Traf2
- Traf3
- Trafamn
- Trance
|
|
Regulation of necroptotic cell death
|
|
|
- Aip1
- Aipa
- Alix
- Api3
- Birc2
- Birc3
- Birc4
- Casp8
- Cdc37
- Chip
- Esa1
- Fadd
- Flot1
- Flot2
- Hsp86
- Hsp86-1
- Hsp90aa1
- Hspca
- Itch
- M17s1
- Miha
- Mlkl
- Mort1
- Ogt
- Park2
- Pdcd6ip
- Peli1
- Prkn
- Rinp
- Rip
- Rip3
- Ripk1
- Ripk3
- Rps27a
- Sdcbp
- Stub1
- Tradd
- Traf2
- Uba52
- Uba80
- Ubb
- Ubc
- Ubce7
- Ubcep1
- Ubcep2
- Ube2l3
- Xiap
|
|
TNFR1-induced proapoptotic signaling
|
|
|
- Aipa
- Api3
- Birc2
- Birc3
- Birc4
- Cyld
- Cyld1
- Fadd
- Ikbke
- Ikke
- Ikki
- Kiaa0849
- Mib2
- Miha
- Mort1
- Otud1
- Otud7b
- Paul
- Rbck
- Rbck1
- Rinp
- Rip
- Ripk1
- Rnf31
- Skd
- Spata2
- Tbk1
- Tnf
- Tnfa
- Tnfaip3
- Tnfip3
- Tnfr-1
- Tnfr1
- Tnfrsf1a
- Tnfsf2
- Tradd
- Traf2
- Ubce7ip3
- Ubp41
- Uip28
- Unp
- Usp2
- Usp21
- Usp23
- Usp4
- Xiap
|
|
TNFR1-induced NF-kappa-B signaling pathway
|
|
|
- Aipa
- Api3
- Birc2
- Birc3
- Birc4
- Chuk
- Cyld
- Cyld1
- Gnb2-rs1
- Gnb2l1
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Kiaa0733
- Kiaa0849
- Kiaa4135
- Map3k7
- Map3k7ip1
- Map3k7ip2
- Map3k7ip3
- Miha
- Nemo
- Optn
- Otud1
- Otud7b
- Paul
- Rack1
- Rbck
- Rbck1
- Rinp
- Rip
- Ripk1
- Rnf31
- Spata2
- Tab1
- Tab2
- Tab3
- Tak1
- Tnf
- Tnfa
- Tnfaip3
- Tnfip3
- Tnfr-1
- Tnfr1
- Tnfrsf1a
- Tnfsf2
- Tradd
- Traf1
- Traf2
- Ubce7ip3
- Ubp41
- Uip28
- Unp
- Usp2
- Usp21
- Usp23
- Usp4
- Xiap
|
|
IKK complex recruitment mediated by RIP1
|
|
|
- Birc2
- Birc3
- Blu
- Cd14
- Chuk
- Croc1
- Esop1
- Ikbkb
- Ikbkg
- Ikka
- Ikkb
- Kiaa0524
- Lps
- Ly96
- Md2
- Nemo
- Rinp
- Rip
- Rip3
- Ripk1
- Ripk3
- Rps27a
- Sarm1
- Ticam1
- Ticam2
- Tirp
- Tlr4
- Traf6
- Tram
- Trif
- Uba52
- Uba80
- Ubb
- Ubc
- Ubc4
- Ubcep1
- Ubcep2
- Ubch4
- Ubch5b
- Ube2d1
- Ube2d2
- Ube2d2a
- Ube2d3
- Ube2n
- Ube2v1
|
|
Neurexins and neuroligins
|
|
|
- Argbp2
- Cask
- Dal1
- Dap2
- Dap3
- Dlg2
- Dlg3
- Dlg4
- Dlgap1
- Dlgap2
- Dlgap3
- Dlgap4
- Dlgh2
- Dlgh3
- Dlgh4
- Epb4
- Epb4.1
- Epb4.1l1
- Epb4.1l2
- Epb4.1l3
- Epb4.1l5
- Epb41
- Epb41l1
- Epb41l2
- Epb41l3
- Epb41l5
- Gkap
- Gprc1a
- Gprc1e
- Grm1
- Grm5
- Homer1
- Homer2
- Homer3
- Kiaa0338
- Kiaa0416
- Kiaa0578
- Kiaa0777
- Kiaa0964
- Kiaa0987
- Kiaa1070
- Kiaa1366
- Kiaa1548
- Kiaa1650
- Kiaa4056
- Kiaa4162
- Lin-2
- Lrrtm1
- Lrrtm2
- Lrrtm3
- Lrrtm4
- Mglur1
- Mglur5
- Nl4*
- Nlgn1
- Nlgn2
- Nlgn3
- Nlgn4
- Nlgn4l
- Nlgn4x
- Nrxn1
- Nrxn2
- Nrxn3
- Prosap2
- Psd95
- Sapap4
- Shank1
- Shank3
- Sorbs2
- Vesl1
- Vesl2
|
|
Nuclear Envelope Breakdown
|
|
|
- Baf
- Banf1
- Caper
- Emd
- L2bp1
- Rbm39
- Rnpc2
- Sta
- Vrk1
- Vrk2
|
|
Integrin cell surface interactions
|
|
|
- Bsg
- Cd44
- Cd47
- Cdh1
- Col13a1
- Col16a1
- Col18a1
- Col4a1
- Col4a2
- Col4a3
- Col4a4
- Col9a1
- Col9a2
- Col9a3
- Comp
- Eta-1
- F11r
- Fbn-1
- Fbn1
- Fga
- Fgb
- Fgg
- Fn1
- Hxb
- Ibsp
- Icam-1
- Icam-2
- Icam1
- Icam2
- Icam3
- Icam4
- Icam5
- Itga1
- Itga10
- Itga11
- Itga2
- Itga2b
- Itga3
- Itga4
- Itga5
- Itga6
- Itga8
- Itga9
- Itgad
- Itgae
- Itgal
- Itgam
- Itgav
- Itgax
- Itgb1
- Itgb2
- Itgb3
- Itgb5
- Itgb6
- Itgb7
- Itgb8
- Jam1
- Jam2
- Jam3
- Jcam
- Jcam1
- Lcn
- Ldc
- Lfa-1
- Lum
- Ly-15
- Ly-24
- Madcam1
- Op
- Pecam
- Pecam-1
- Pecam1
- Spp-1
- Spp1
- Thbs1
- Tlcn
- Tnc
- Tsp1
- Vcam-1
- Vcam1
- Vejam
- Vtn
|
|
Proton-coupled monocarboxylate transport
|
|
|
- Bsg
- Emb
- Gp70
- Mct1
- Mct2
- Mct3
- Mct4
- Slc16a1
- Slc16a3
- Slc16a7
- Slc16a8
|
|
Activation of BIM and translocation to mitochondria
|
|
|
- Bcl2l11
- Bim
- Dlc1
- Dncl1
- Dnclc1
- Dynll1
- Jnk1
- Mapk8
- Prkm8
|
|
Activation of BMF and translocation to mitochondria
|
|
|
- Bmf
- Dlc2
- Dynll2
- Jnk1
- Mapk8
- Prkm8
|
|
O-linked glycosylation
|
|
|
- Ago61
- B3galnt2
- B3gnt1
- B3gnt6
- B4gat1
- Dag1
- Eogtl
- Gtdc2
- Gyltl1b
- Kiaa0609
- Large
- Large1
- Large2
- Pomgnt1
- Pomgnt2
- Pomk
- Pomt1
- Pomt2
- Sgk196
|
|
Reactions specific to the hybrid N-glycan synthesis pathway
|
|
|
|
|
DAP12 interactions
|
- Beta-2-microglobulin
- C-type lectin domain family 5 member A
- CMRF35-like molecule 2
- CMRF35-like molecule 7
- Class Ib MHC antigen Qa-2
- H-2 class I histocompatibility antigen, D-37 alpha chain
- H-2 class I histocompatibility antigen, D-P alpha chain
- H-2 class I histocompatibility antigen, K-B alpha chain
- H-2 class I histocompatibility antigen, Q10 alpha chain
- H-2 class I histocompatibility antigen, Q7 alpha chain
- H-2 class I histocompatibility antigen, TLA(B) alpha chain
- Histocompatibility 2, M region locus 10.1
- Histocompatibility 2, M region locus 10.2
- Histocompatibility 2, M region locus 10.3
- Histocompatibility 2, M region locus 10.4
- Histocompatibility 2, M region locus 10.5
- Histocompatibility 2, M region locus 10.6
- Histocompatibility 2, M region locus 11 (Fragment)
- Histocompatibility 2, M region locus 1
- Histocompatibility 2, M region locus 2
- Histocompatibility 2, M region locus 3
- Histocompatibility 2, M region locus 5
- Histocompatibility 2, M region locus 9
- Histocompatibility 2, Q region locus 1
- Histocompatibility 2, Q region locus 2
- Histocompatibility 2, Q region locus 4
- Histocompatibility 2, T region locus 22
- KIR-like receptor 2 KIRL2.1
- Killer cell immunoglobulin-like receptor 3DL1
- Killer cell lectin-like receptor subfamily C, member 1
- Killer cell lectin-like receptor subfamily C, member 2
- Killer cell lectin-like receptor subfamily C, member 3
- Natural killer cells antigen CD94
- Predicted gene 5150
- SIGLEC-I
- Sialic acid-binding Ig-like lectin 10
- TYRO protein tyrosine kinase-binding protein
- Triggering receptor expressed on myeloid cells 1
- Triggering receptor expressed on myeloid cells 2
|
|
- 381484
- B2m
- Cd300e
- Cd300lb
- Cd300le
- Cd94
- Clec5a
- Clecsf5
- Clm2
- Dap12
- Gm11132
- Gm5150
- H-2M3
- H2-D1
- H2-Gs10
- H2-K
- H2-K1
- H2-M1
- H2-M10.1
- H2-M10.2
- H2-M10.3
- H2-M10.4
- H2-M10.5
- H2-M10.6
- H2-M11
- H2-M2
- H2-M3
- H2-M5
- H2-M9
- H2-Q1
- H2-Q10
- H2-Q2
- H2-Q4
- H2-Q6
- H2-Q7
- H2-T22
- H2-T23
- H2-T3
- H2-gs10
- Irem3
- Karap
- Kir3dl1
- Kir3dl2
- Klrc1
- Klrc2
- Klrc3
- Klrd1
- Lmir5
- M10
- M9
- Mdl1
- Nkg2a
- Nkg2c
- Siglec10
- Siglec15
- Siglecg
- Trem1
- Trem2
- Trem2a
- Trem2b
- Trem2c
- Tyrobp
|
|
Endosomal/Vacuolar pathway
|
- Beta-2-microglobulin
- Class Ib MHC antigen Qa-2
- H-2 class I histocompatibility antigen, D-37 alpha chain
- H-2 class I histocompatibility antigen, D-P alpha chain
- H-2 class I histocompatibility antigen, K-B alpha chain
- H-2 class I histocompatibility antigen, Q10 alpha chain
- H-2 class I histocompatibility antigen, Q7 alpha chain
- H-2 class I histocompatibility antigen, TLA(B) alpha chain
- Histocompatibility 2, M region locus 10.1
- Histocompatibility 2, M region locus 10.2
- Histocompatibility 2, M region locus 10.3
- Histocompatibility 2, M region locus 10.4
- Histocompatibility 2, M region locus 10.5
- Histocompatibility 2, M region locus 10.6
- Histocompatibility 2, M region locus 11 (Fragment)
- Histocompatibility 2, M region locus 1
- Histocompatibility 2, M region locus 2
- Histocompatibility 2, M region locus 3
- Histocompatibility 2, M region locus 5
- Histocompatibility 2, M region locus 9
- Histocompatibility 2, Q region locus 1
- Histocompatibility 2, Q region locus 2
- Histocompatibility 2, Q region locus 4
- Histocompatibility 2, T region locus 22
- Leucyl-cystinyl aminopeptidase
|
|
- B2m
- Gm11132
- H-2M3
- H2-D1
- H2-Gs10
- H2-K
- H2-K1
- H2-M1
- H2-M10.1
- H2-M10.2
- H2-M10.3
- H2-M10.4
- H2-M10.5
- H2-M10.6
- H2-M11
- H2-M2
- H2-M3
- H2-M5
- H2-M9
- H2-Q1
- H2-Q10
- H2-Q2
- H2-Q4
- H2-Q6
- H2-Q7
- H2-T22
- H2-T23
- H2-T3
- H2-gs10
- Lnpep
- M10
- M9
|
|
Activation of SMO
|
|
|
- Adrbk1
- Arrb1
- Arrb2
- Boc
- Cdo
- Cdon
- Csnk1a1
- Dhh
- Drc4
- Gas-1
- Gas1
- Gas11
- Gas8
- Grk2
- Hhg1
- Ihh
- Kif3
- Kif3a
- Ptch
- Ptch1
- Shh
- Smo
- Smoh
|
|
Calmodulin induced events
|
|
|
- Adrbk1
- Calm
- Calm1
- Cam
- Cam1
- Grk2
- Pkca
- Pkcc
- Pkcd
- Pkcg
- Prkca
- Prkcc
- Prkcd
- Prkcg
|
|
Thrombin signalling through proteinase activated receptors (PARs)
|
|
|
- Arrb1
- Arrb2
- Cf2
- Cf2r
- Erk1
- Erk2
- F2
- F2r
- F2rl2
- F2rl3
- Gna-11
- Gna-12
- Gna-13
- Gna-14
- Gna-15
- Gna11
- Gna12
- Gna13
- Gna14
- Gna15
- Gnaq
- Gnb1
- Gnb2
- Gnb3
- Gnb4
- Gnb5
- Gng1
- Gng10
- Gng11
- Gng12
- Gng13
- Gng2
- Gng3
- Gng4
- Gng5
- Gng7
- Gng8
- Gng9
- Gngt1
- Gngt11
- Gngt2
- Gngt3
- Gngt4
- Gngt5
- Gngt7
- Gngt8
- Gngt9
- Mapk
- Mapk1
- Mapk3
- Par1
- Par3
- Par4
- Prkm1
- Prkm3
- Src
|
|
Beta defensins
|
|
|
- Bdef4
- Ccr6
- Cmkbr6
- Defb1
- Defb14
- Defb18
- Defb19
- Defb21
- Defb24
- Defb25
- Defb28
- Defb30
- Defb36
- Defb4
- Defb41
- Defb42
- Defb43
- Defb44
- Defb47
- Defb48
- EG432867
- EG654465
- OTTMUSG00000015852
- Tdl
- Tlr1
- Tlr2
|
|
Gluconeogenesis
|
|
|
- Aldo1
- Aldo2
- Aldo3
- Aldoa
- Aldob
- Aldoc
- Ci2
- Eno-2
- Eno-3
- Eno2
- Eno3
- Eno4
- Fbp
- Fbp1
- Fbp2
- Fbp3
- G6pc
- G6pc1
- G6pc2
- G6pc3
- G6pt
- Gapd
- Gapd-s
- Gapdh
- Gapdhs
- Gapds
- Gpi
- Gpi1
- Igrp
- Pc
- Pck1
- Pck2
- Pcx
- Pepck
- Pgam1
- Pgam2
- Pgk-1
- Pgk-2
- Pgk1
- Pgk2
- Scrg2
- Slc37a1
- Slc37a2
- Slc37a4
- Tpi
- Tpi1
- Ugrp
|
|
Hyaluronan uptake and degradation
|
|
|
- Cd44
- Chp
- Chp1
- Crsbp1
- Feel2
- Gus
- Gus-s
- Gusb
- Hare
- Hexa
- Hexb
- Hmmr
- Hyal1
- Hyal2
- Hyal3
- Hyl3
- Ihabp
- Ly-24
- Lyve1
- Nhe1
- Rhamm
- Sid470
- Slc9a1
- Stab2
- Xlkd1
|
|
Negative regulation of FGFR4 signaling
|
|
|
- Aigf
- Betakl
- Cbl
- Erk1
- Erk2
- Fgf-1
- Fgf-2
- Fgf-4
- Fgf-6
- Fgf-9
- Fgf1
- Fgf15
- Fgf16
- Fgf17
- Fgf18
- Fgf2
- Fgf20
- Fgf23
- Fgf4
- Fgf6
- Fgf8
- Fgf9
- Fgfa
- Fgfr-4
- Fgfr4
- Frs2
- Frs2a
- Hstf2
- Kfgf
- Klb
- Mapk
- Mapk1
- Mapk3
- Mpk-11
- Prkm1
- Prkm3
- Ptpn11
- Rps27a
- Uba52
- Uba80
- Ubb
- Ubc
- Ubcep1
- Ubcep2
|
|
PI3K Cascade
|
|
|
- Aigf
- Bek
- Betakl
- Ect1
- Fgf-1
- Fgf-2
- Fgf-3
- Fgf-4
- Fgf-5
- Fgf-6
- Fgf-7
- Fgf-9
- Fgf1
- Fgf10
- Fgf15
- Fgf16
- Fgf17
- Fgf18
- Fgf2
- Fgf20
- Fgf22
- Fgf23
- Fgf3
- Fgf4
- Fgf5
- Fgf6
- Fgf7
- Fgf8
- Fgf9
- Fgfa
- Fgfr-4
- Fgfr1
- Fgfr2
- Fgfr3
- Fgfr4
- Flg
- Flk-2
- Flt-3
- Flt3
- Flt3l
- Flt3lg
- Frs2
- Frs2a
- Gab1
- Gab2
- Hstf2
- Int-2
- Irs-1
- Irs1
- Irs2
- Kfgf
- Kgf
- Kl
- Klb
- Mfr3
- Mpk-11
- Pik3c3
- Pik3ca
- Pik3cb
- Pik3r1
- Pik3r2
- Pik3r4
- Ptpn11
- Sam3
- Tlr9
- Vps15
- Vps34
|
|
FRS-mediated FGFR4 signaling
|
|
|
- Aigf
- Betakl
- Fgf-1
- Fgf-2
- Fgf-4
- Fgf-6
- Fgf-9
- Fgf1
- Fgf15
- Fgf16
- Fgf17
- Fgf18
- Fgf2
- Fgf20
- Fgf23
- Fgf4
- Fgf6
- Fgf8
- Fgf9
- Fgfa
- Fgfr-4
- Fgfr4
- Frs2
- Frs2a
- Frs2b
- Frs3
- Hras
- Hras1
- Hstf2
- Kfgf
- Klb
- Kras
- Kras2
- Mpk-11
- Nras
- Ptpn11
- Sos1
|
|
PI-3K cascade:FGFR4
|
|
|
- Aigf
- Betakl
- Fgf-1
- Fgf-2
- Fgf-4
- Fgf-6
- Fgf-9
- Fgf1
- Fgf15
- Fgf16
- Fgf17
- Fgf18
- Fgf2
- Fgf20
- Fgf23
- Fgf4
- Fgf6
- Fgf8
- Fgf9
- Fgfa
- Fgfr-4
- Fgfr4
- Frs2
- Frs2a
- Gab1
- Hstf2
- Kfgf
- Klb
- Mpk-11
- Pik3ca
- Pik3r1
- Ptpn11
|
|