GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **576 - 600** of **2074** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
Surfactant metabolism	Adenosine deaminase 2 Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Cytokine receptor common subunit beta Cytoskeleton-associated protein 4 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha LIM and cysteine-rich domains protein 1 Napsin-A P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Pepsin A-3 Pepsin A-4 Pepsin A-5 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Scavenger receptor cysteine-rich domain-containing protein DMBT1 Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Surfactant-associated protein 3 Thyroid transcription factor 1-associated protein 26 Transcription factor GATA-6 Transcription termination factor 1	O95436 O96009 P07988 P08913 P09668 P0C7M3 P0DJD7 P0DJD8 P0DJD9 P11686 P15509 P18825 P29274 P29275 P32927 P35247 P41231 Q06495 Q07065 Q15361 Q8IWL1 Q8IWL2 Q8IZF2 Q92908 Q99758 Q9NZK5 Q9NZU5 Q9P031 Q9UGM3 Q9UIJ5	ABC3 ABCA3 ADA2 ADGF ADGRF5 ADORA2 ADORA2A ADORA2B ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR BR22 CCDC59 CECR1 CKAP4 COLEC4 COLEC5 COLEC7 CPSB CSF2R CSF2RA CSF2RB CSF2RY CTSH DMBT1 GATA6 GP340 GPR116 IDGFL IL3RB IL5RB KIAA0758 LMCD1 NAP1 NAPA NAPSA NPT2 P2RU1 P2RY2 PGA3 PGA4 PGA5 PSAP PSPD REAM REC SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH SLC17A2 SLC34A1 SLC34A2 TAP26 TTF1 ZDHHC2 ZNF372	Homo sapiens (human)
Ribavirin ADME	Adenosine deaminase Adenosine kinase Cytosolic purine 5'-nucleotidase Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 3 Inosine triphosphate pyrophosphatase Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Purine nucleoside phosphorylase Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3	O43868 P00491 P00813 P15531 P22392 P49902 P55263 Q99808 Q9BY32 Q9BZD2 Q9HAS3	ADA ADA1 ADK C20orf37 CNT2 CNT3 ENT1 ENT3 ITPA NDPKA NM23 NM23B NME1 NME2 NP NT5B NT5C2 NT5CP PNP PNT5 SLC28A2 SLC28A3 SLC29A1 SLC29A3	Homo sapiens (human)
Abacavir metabolism	Adenosine deaminase-like protein Alcohol dehydrogenase 1A Cytosolic purine 5'-nucleotidase Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	P07327 P35558 P49902 Q6DHV7	ADAL ADAL1 ADH1 ADH1A NT5B NT5C2 NT5CP PCK1 PEPCK1 PNT5	Homo sapiens (human)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2a Adenosine receptor A2b Adenosine receptor A3	P0DMS8 P29274 P29275 P30542	ADORA1 ADORA2 ADORA2A ADORA2B ADORA3	Homo sapiens (human)
NGF-independant TRKA activation	Adenosine receptor A2a BDNF/NT-3 growth factors receptor High affinity nerve growth factor receptor Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide	P04629 P18509 P29274 P41586 Q16620	ADCYAP1 ADCYAP1R1 ADORA2 ADORA2A MTC NTRK1 NTRK2 TRK TRKA TRKB	Homo sapiens (human)
ADORA2B mediated anti-inflammatory cytokines production	Adenosine receptor A2b Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Interleukin-6 cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A8MTJ3 O14610 O14775 O43306 O60262 O60266 O60503 O95622 P04899 P05231 P08754 P10644 P13861 P16520 P17612 P19086 P22612 P22694 P29275 P31321 P31323 P40145 P50150 P50151 P51817 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADORA2B GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP IFNB2 IL6 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PKX1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX TSE1	Homo sapiens (human)
Bicarbonate transporters	Adenosylhomocysteinase 3 Anion exchange protein 2 Anion exchange protein 3 Anion exchange protein 4 Band 3 anion transport protein Electrogenic sodium bicarbonate cotransporter 1 Electrogenic sodium bicarbonate cotransporter 4 Electroneutral sodium bicarbonate exchanger 1 Sodium bicarbonate cotransporter 3 Sodium-driven chloride bicarbonate exchanger	P02730 P04920 P48751 Q2Y0W8 Q6U841 Q96HN2 Q96Q91 Q9BY07 Q9Y6M7 Q9Y6R1	AE1 AE2 AE3 AE4 AHCYL2 BT DI EPB3 EPB3L1 HKB3 KIAA0739 KIAA0828 MPB3L NBC NBC1 NBC2 NBC2B NBC3 NBC4 NBCE1 NBCN2 NBCn1 NCBE NDCBE1 SBC2 SBC5 SLC4A1 SLC4A10 SLC4A2 SLC4A3 SLC4A4 SLC4A5 SLC4A6 SLC4A7 SLC4A8 SLC4A9	Homo sapiens (human)
Methylation	Adenosylhomocysteinase Arsenite methyltransferase Catechol O-methyltransferase Cytochrome P450 1A2 Glutathione S-transferase omega-1 Methionine adenosyltransferase 2 subunit beta Methionine synthase reductase Methionine synthase Methyltransferase N6AMT1 Multifunctional methyltransferase subunit TRM112-like protein Nicotinamide N-methyltransferase S-adenosylmethionine synthase isoform type-1 S-adenosylmethionine synthase isoform type-2 Thiopurine S-methyltransferase	P05177 P21964 P23526 P31153 P40261 P51580 P78417 Q00266 Q99707 Q9HBK9 Q9NZL9 Q9UBK8 Q9UI30 Q9Y5N5	AHCY AMS1 AMS2 AS3MT C21orf127 COMT CYP1A2 CYT19 GSTO1 GSTTLP28 HEMK2 KMT9 MAT1A MAT2A MAT2B MATA1 MATA2 MTR MTRR N6AMT1 NNMT PRED28 SAHH TGR TPMT TRMT112	Homo sapiens (human)
Sulfur amino acid metabolism	Adenosylhomocysteinase Betaine--homocysteine S-methyltransferase 1 Methionine synthase reductase Methionine synthase S-adenosylmethionine synthase isoform type-1 S-methylmethionine--homocysteine S-methyltransferase BHMT2	P23526 Q00266 Q93088 Q99707 Q9H2M3 Q9UBK8	AHCY AMS1 BHMT BHMT2 MAT1A MATA1 MTR MTRR SAHH	Homo sapiens (human)
Metabolism of ingested SeMet, Sec, MeSec into H2Se	Adenosylhomocysteinase Cystathionine beta-synthase Cystathionine gamma-lyase Glycine N-methyltransferase Histamine N-methyltransferase Nicotinamide N-methyltransferase S-adenosylmethionine synthase isoform type-1 Selenocysteine lyase	P23526 P32929 P35520 P40261 P50135 Q00266 Q14749 Q96I15	AHCY AMS1 CBS CTH GNMT HNMT MAT1A MATA1 NNMT SAHH SCL SCLY	Homo sapiens (human)
Defective AHCY causes HMAHCHD	Adenosylhomocysteinase	P23526	AHCY SAHH	Homo sapiens (human)
G alpha (z) signalling events	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C gamma type Protein kinase C theta type Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 19 Regulator of G-protein signaling 20 Regulator of G-protein signaling 4 Regulator of G-protein signaling protein-like	A5PLK6 A8MTJ3 O14610 O14775 O15492 O43306 O60262 O60266 O60503 O76081 O95622 P04899 P05129 P05771 P08754 P08913 P16520 P17252 P18089 P18825 P19086 P24723 P40145 P49795 P49798 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q02156 Q04759 Q05655 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UGC6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR GAIP GNAI1 GNAI2 GNAI2B GNAI3 GNAI3IP GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKCA PKCB PKCD PKCE PKCG PKCL PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCE PRKCG PRKCH PRKCL PRKCQ PRKCT RGS16 RGS17 RGS19 RGS20 RGS4 RGSL RGSL1 RGSL2 RGSR RGSZ1 RGSZ2 ZGAP1	Homo sapiens (human)
Vasopressin regulates renal water homeostasis via Aquaporins	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rab11 family-interacting protein 2 Ras-related protein Rab-11A Unconventional myosin-Vb Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14610 O14775 O43306 O60262 O60266 O60503 O95622 P01185 P10644 P13861 P16520 P17612 P22612 P22694 P29972 P30518 P31321 P31323 P40145 P41181 P50150 P50151 P51828 P55087 P59768 P61952 P62491 P62873 P62879 P63092 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q7L804 Q8NFM4 Q92482 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9ULV0	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADHR AQP1 AQP2 AQP3 AQP4 ARVP AVP AVPR2 CHIP28 DIR DIR3 GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0941 KIAA1060 KIAA1119 MYO5B PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B RAB11 RAB11A RAB11FIP2 TSE1 V2R VP	Homo sapiens (human)
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Calmodulin-1 Neurobeachin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P0DP23 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 Q08462 Q08828 Q8NFM4 Q8NFP9	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 BCL8B CALM CALM1 CAM CAM1 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 KIAA1544 LYST2 NBEA PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1	Homo sapiens (human)
GPER1 signaling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 G-protein coupled estrogen receptor 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Integrin alpha-5 Integrin beta-1 Proto-oncogene tyrosine-protein kinase Src cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A8MTJ3 O14610 O14775 O43306 O60262 O60266 O60503 O95622 P04899 P05556 P08648 P08754 P10644 P12931 P13861 P16520 P17612 P19086 P22612 P22694 P31321 P31323 P40145 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q99527 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CEPR CMKRL2 DRY12 FNRA FNRB GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPER GPER1 GPR30 GSP ITGA5 ITGB1 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 MDF2 MSK12 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B SRC SRC1 TSE1	Homo sapiens (human)
Glucagon signaling in metabolic regulation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Glucagon receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Pro-glucagon	O43306 O60262 O60266 O60503 O95622 P01275 P16520 P40145 P47871 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GCG GCGR GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT10 GNGT11 GNGT3 GNGT4 GNGT5 GNGT7 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3	A8MTJ3 O43306 O60266 O60503 O95622 P04899 P08754 P38405 P40145 P51828 P63096 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAI1 GNAI2 GNAI2B GNAI3 GNAL GNAT3 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(olf) subunit alpha	O43306 O60266 O60503 O95622 P38405 P40145 P51828 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAL KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
PKA activation in glucagon signalling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q5JWF2 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAS GNAS1 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1	Homo sapiens (human)
CREB1 phosphorylation through the activation of Adenylate Cyclase	Adenylate cyclase type 1 Adenylate cyclase type 8 Calmodulin-1 cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	P0DP23 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51817 Q08828	ADCY1 ADCY8 CALM CALM1 CAM CAM1 PKACA PKR1 PKR2 PKX1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX TSE1	Homo sapiens (human)
Hedgehog 'off' state	Adenylate cyclase type 10 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Centriole and centriolar satellite protein OFD1 Cytoplasmic dynein 2 heavy chain 1 G-protein coupled receptor 161 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Intraflagellar transport protein 122 homolog Intraflagellar transport protein 140 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 52 homolog Intraflagellar transport protein 57 homolog Intraflagellar transport protein 88 homolog Kinesin-like protein KIF3A Kinesin-like protein KIF7 Protein fantom Protein fuzzy homolog Protein inturned Protein patched homolog 1 Protein smoothened Suppressor of fused homolog Tectonic-like complex member MKS1 Tetratricopeptide repeat protein 21B Transcriptional activator GLI3 Tubby-related protein 3 WD repeat-containing protein 19 WD repeat-containing protein 35 Zinc finger protein GLI1 Zinc finger protein GLI2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O75386 O75665 O95622 P08151 P10070 P10071 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q13099 Q13635 Q2M1P5 Q5JWF2 Q68CZ1 Q7Z4L5 Q8N6U8 Q8NCM8 Q8NEZ3 Q8NFM4 Q96PN6 Q96RY7 Q99835 Q9BT04 Q9HBG6 Q9NWB7 Q9NXB0 Q9P2L0 Q9UG01 Q9ULD6 Q9UMX1 Q9Y366 Q9Y496	ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 C20orf9 CXorf5 DERP8 DHC1B DHC2 DNCH2 DYH1B DYNC2H1 ESRRBL1 FTM FUZ FY GLI GLI1 GLI2 GLI3 GNAS GNAS1 GPR161 GSP HIPPI IFT121 IFT122 IFT139 IFT140 IFT144 IFT172 IFT52 IFT57 IFT88 INTU KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0590 KIAA1005 KIAA1060 KIAA1179 KIAA1284 KIAA1336 KIAA1638 KIAA1992 KIAA1997 KIF3 KIF3A KIF7 MKS1 NGD5 NPHP8 OFD1 PDZD6 PDZK6 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PTCH PTCH1 RPGRIP1L SAC SMO SMOH SPG SUFU TG737 THP TSE1 TTC10 TTC21B TUBL3 TULP3 WDR10 WDR140 WDR19 WDR35 WDTC2	Homo sapiens (human)
Olfactory Signaling Pathway	Adenylate cyclase type 3 Anoctamin-2 Cyclic nucleotide-gated channel alpha-2 Cyclic nucleotide-gated channel alpha-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(olf) subunit alpha Olfactory receptor 10A6 Olfactory receptor 10G3 Olfactory receptor 10G4 Olfactory receptor 10G7 Olfactory receptor 10H2 Olfactory receptor 10H5 Olfactory receptor 10J5 Olfactory receptor 10S1 Olfactory receptor 10X1 Olfactory receptor 11A1 Olfactory receptor 11H4 Olfactory receptor 11H6 Olfactory receptor 13C3 Olfactory receptor 14A2 Olfactory receptor 14J1 Olfactory receptor 1A1 Olfactory receptor 1C1 Olfactory receptor 1D2 Olfactory receptor 1D5 Olfactory receptor 1E1 Olfactory receptor 1N2 Olfactory receptor 2A1/2A42 Olfactory receptor 2A25 Olfactory receptor 2A7 Olfactory receptor 2AT4 Olfactory receptor 2B11 Olfactory receptor 2C1 Olfactory receptor 2F1 Olfactory receptor 2J1 Olfactory receptor 2J2 Olfactory receptor 2J3 Olfactory receptor 2L13 Olfactory receptor 2M2 Olfactory receptor 2M7 Olfactory receptor 2S2 Olfactory receptor 2T1 Olfactory receptor 2T4 Olfactory receptor 2W1 Olfactory receptor 2W3 Olfactory receptor 3A1 Olfactory receptor 4C12 Olfactory receptor 4D2 Olfactory receptor 4F17 Olfactory receptor 4L1 Olfactory receptor 4Q3 Olfactory receptor 51B5 Olfactory receptor 51D1 Olfactory receptor 51E1 Olfactory receptor 51E2 Olfactory receptor 51L1 Olfactory receptor 52B6 Olfactory receptor 56A4 Olfactory receptor 5AL1 Olfactory receptor 5D14 Olfactory receptor 5K1 Olfactory receptor 5P3 Olfactory receptor 6F1 Olfactory receptor 6P1 Olfactory receptor 7C1 Olfactory receptor 7D4 Olfactory receptor 7G2 Olfactory receptor 8B3 Olfactory receptor 8D1 Olfactory receptor 8K3 Olfactory receptor 8U8 Olfactory receptor 9G1	A4D2G3 A6NND4 O43869 O60266 O60403 O76001 O76002 O76099 O95371 P0C617 P0C7N1 P30953 P34982 P38405 P47881 P58170 P58180 P62873 Q13607 Q15619 Q16280 Q5JQS5 Q7Z3T1 Q8IV77 Q8N349 Q8NG81 Q8NG98 Q8NG99 Q8NGA6 Q8NGA8 Q8NGC4 Q8NGC7 Q8NGC9 Q8NGF0 Q8NGF3 Q8NGG8 Q8NGH8 Q8NGJ5 Q8NGL3 Q8NGN2 Q8NGN3 Q8NGN6 Q8NGR9 Q8NGS6 Q8NGT9 Q8NGX9 Q8NGY0 Q8NGZ6 Q8NH00 Q8NH05 Q8NH43 Q8NH51 Q8NH74 Q8NH87 Q8NHB7 Q8NHC4 Q8TCB6 Q8WZ84 Q8WZ94 Q96R28 Q96R45 Q96R54 Q96R67 Q9GZK6 Q9GZK7 Q9H255 Q9H339 Q9NQ90 Q9NQN1 Q9P1Q5 Q9P2W3 Q9UGF5 Q9Y3N9	ADCY3 ANO2 C12orf3 C14orf13 CNCA CNCA1 CNCG2 CNGA2 CNGA4 GNAL GNB1 GNG13 GPR164 KIAA0511 OLF3 OLFR1 OLFRA03 OR10A6 OR10G3 OR10G4 OR10G7 OR10H2 OR10H5 OR10J5 OR10S1 OR10X1 OR10X1P OR11A1 OR11A2 OR11H4 OR11H6 OR13C3 OR14A2 OR14J1 OR1A1 OR1C1 OR1D2 OR1D5 OR1E1 OR1E5 OR1E6 OR1E9P OR1N2 OR2A1 OR2A25 OR2A25P OR2A27 OR2A42 OR2A7 OR2AT4 OR2B11 OR2C1 OR2C2P OR2F1 OR2F3 OR2F3P OR2F4 OR2F5 OR2J1 OR2J1P OR2J2 OR2J3 OR2L13 OR2L14 OR2M2 OR2M7 OR2S2 OR2T1 OR2T4 OR2W1 OR2W3 OR2W3P OR2W8P OR3A1 OR4C12 OR4D2 OR4F11P OR4F17 OR4F18 OR4F19 OR4L1 OR4L2P OR4Q3 OR4Q4 OR51B5 OR51D1 OR51E1 OR51E1P OR51E2 OR51L1 OR52A3P OR52B6 OR56A4 OR5AL1 OR5AL1P OR5AX1 OR5AX1P OR5D14 OR5K1 OR5P3 OR5U1 OR6F1 OR6P1 OR7C1 OR7C4 OR7D4 OR7D4P OR7G2 OR8B3 OR8D1 OR8D3 OR8K3 OR8U8 OR9G1 OR9G5 POGR PSGR PSGR2 TMEM16B	Homo sapiens (human)
Adrenaline,noradrenaline inhibits insulin secretion	Adenylate cyclase type 5 Adenylate cyclase type 6 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent calcium channel subunit alpha-2/delta-2	O14610 O14775 O43306 O60262 O95622 P04899 P08913 P16520 P18825 P50150 P50151 P54284 P59768 P61952 P62873 P62879 P63096 P63211 P63215 P63218 Q01668 Q08289 Q13936 Q9HAV0 Q9NY47 Q9P2W3 Q9UBI6 Q9UK08	ADCY5 ADCY6 ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR CACH2 CACH3 CACN2 CACN4 CACNA1C CACNA1D CACNA2D2 CACNB2 CACNB3 CACNL1A1 CACNL1A2 CACNLB2 CACNLB3 CCHL1A1 CCHL1A2 GNAI1 GNAI2 GNAI2B GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0422 KIAA0558 MYSB	Homo sapiens (human)
Interconversion of nucleotide di- and triphosphates	Adenylate kinase 2, mitochondrial Adenylate kinase 4, mitochondrial Adenylate kinase 7 Adenylate kinase 8 Adenylate kinase 9 Adenylate kinase isoenzyme 1 Adenylate kinase isoenzyme 5 Adenylate kinase isoenzyme 6 CTP synthase 1 CTP synthase 2 Deoxycytidylate deaminase Glutaredoxin-1 Guanylate kinase NAD(P)H pyrophosphatase NUDT13, mitochondrial Nucleoside diphosphate kinase 3 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleoside diphosphate kinase, mitochondrial Putative nucleoside diphosphate kinase Ribonucleoside-diphosphate reductase large subunit Ribonucleoside-diphosphate reductase subunit M2 B Ribonucleoside-diphosphate reductase subunit M2 Thioredoxin reductase 1, cytoplasmic Thioredoxin Thymidylate kinase Thymidylate synthase UMP-CMP kinase dCTP pyrophosphatase 1	O00746 O60361 P00568 P04818 P10599 P15531 P17812 P22392 P23919 P23921 P27144 P30085 P31350 P32321 P35754 P54819 Q13232 Q16774 Q16881 Q5TCS8 Q7LG56 Q86X67 Q96M32 Q96MA6 Q9H773 Q9NRF8 Q9Y3D8 Q9Y6K8	ADK2 AK1 AK2 AK3 AK3L1 AK4 AK5 AK6 AK7 AK8 AK9 AKD1 AKD2 C6orf199 C6orf224 C9orf98 CDC8 CINAP CMK CMPK CMPK1 CTPS CTPS1 CTPS2 DCTD DCTPP1 DTYMK GLRX GMK GMPK GRIM12 GRX GUK1 KDRF NDPKA NM23 NM23B NM23D NME1 NME2 NME2P1 NME3 NME4 NUDT13 P53R2 RR1 RR2 RRM1 RRM2 RRM2B TMPK TRDX TRX TRX1 TS TXN TXNRD1 TYMK TYMS UCK UMK UMPK XTP3TPA	Homo sapiens (human)
Purine ribonucleoside monophosphate biosynthesis	Adenylosuccinate lyase Adenylosuccinate synthetase isozyme 1 Adenylosuccinate synthetase isozyme 2 Amidophosphoribosyltransferase Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Bifunctional purine biosynthesis protein ATIC GMP synthase [glutamine-hydrolyzing] Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Phosphoribosylformylglycinamidine synthase Trifunctional purine biosynthetic protein adenosine-3	O15067 P12268 P20839 P22102 P22234 P30520 P30566 P31939 P49915 Q06203 Q8N142	ADE2 ADSL ADSS ADSS1 ADSS2 ADSSL1 AIRC AMPS ATIC GART GMPS GPAT IMPD1 IMPD2 IMPDH1 IMPDH2 KIAA0361 PAICS PAIS PFAS PGFT PPAT PRGS PURH	Homo sapiens (human)

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