GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1876 - 1900** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Cross-presentation of particulate exogenous antigens (phagosomes)	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Integrin alpha-V Integrin beta-5 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Platelet glycoprotein 4	P04839 P06756 P13498 P14598 P16671 P18084 P19878 Q15080	CD36 CYBA CYBB GP3B GP4 ITGAV ITGB5 MSK8 NCF1 NCF2 NCF4 NOX2 NOXA2 NOXO2 P67PHOX SH3PXD1A SH3PXD4 VNRA VTNR	Homo sapiens (human)
B-WICH complex positively regulates rRNA expression	Actin, cytoplasmic 1 DNA excision repair protein ERCC-6 DNA-directed RNA polymerase I subunit RPA12 DNA-directed RNA polymerase I subunit RPA1 DNA-directed RNA polymerase I subunit RPA2 DNA-directed RNA polymerase I subunit RPA34 DNA-directed RNA polymerase I subunit RPA43 DNA-directed RNA polymerase I subunit RPA49 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Glycogen synthase kinase-3 beta Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Myb-binding protein 1A Nucleolar RNA helicase 2 Protein DEK Protein POLR1D, isoform 2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Splicing factor 3B subunit 1 TATA box-binding protein-associated factor RNA polymerase I subunit A TATA box-binding protein-associated factor RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit C TATA box-binding protein-associated factor RNA polymerase I subunit D TATA-box-binding protein Tyrosine-protein kinase BAZ1B	O15160 O15446 O60264 O60814 O75533 O95602 P04908 P06899 P0C5Y9 P0DPB5 P16104 P19388 P20226 P20671 P23527 P33778 P35659 P49841 P52434 P53803 P57053 P58876 P60709 P61218 P62805 P62807 P62875 P68431 P84243 Q03468 Q09472 Q15572 Q15573 Q16777 Q16778 Q3B726 Q53T94 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q92830 Q92831 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BQG0 Q9BTM1 Q9GZS1 Q9H5J8 Q9H9Y6 Q9NR30 Q9P1U0 Q9UIG0	ACTB ASE1 BAZ1B CAST CD3EAP CSB DDX21 DEK EP300 ERCC6 GCN5 GCN5L2 GSK3B GTF2D1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 JOSD3 KAT2A KAT2B MYBBP1A P160 P300 PAF49 PAF53 PCAF POLR1A POLR1B POLR1C POLR1D POLR1E POLR1F POLR1G POLR1H POLR2E POLR2F POLR2H POLR2K POLR2L POLRF PRAF1 RPA12 SAP155 SF3B1 SMARCA5 SNF2H TAF1A TAF1B TAF1C TAF1D TBP TF2D TFIID TSH2B TWISTNB WBSC10 WBSCR10 WBSCR9 WCRF135 WSTF ZNRD1	Homo sapiens (human)
Negative regulation of FGFR3 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43320 O76093 P05230 P08620 P09038 P0CG47 P0CG48 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 HST HSTF1 HYPF KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	Alpha-parvin Integrin beta-1 Integrin-linked protein kinase Paxillin	P05556 P49023 Q13418 Q9NVD7	FNRB ILK ILK1 ILK2 ITGB1 MDF2 MSK12 MXRA2 PARVA PXN	Homo sapiens (human)
VEGF ligand-receptor interactions	Placenta growth factor Vascular endothelial growth factor A, long form Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D	O43915 P15692 P49763 P49765 P49767	FIGF PGF PGFL PLGF VEGF VEGFA VEGFB VEGFC VEGFD VRF	Homo sapiens (human)
Organic anion transport	Organic anion transporter 3 Solute carrier family 22 member 11 Solute carrier family 22 member 12 Solute carrier family 22 member 6 Solute carrier family 22 member 7	Q4U2R8 Q8TCC7 Q96S37 Q9NSA0 Q9Y694	NLT OAT1 OAT2 OAT3 OAT4 OATL4 PAHT SLC22A11 SLC22A12 SLC22A6 SLC22A7 SLC22A8 URAT1	Homo sapiens (human)
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	Bone morphogenetic protein 7 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Cytochrome c oxidase subunit 7A1, mitochondrial Heterogeneous nuclear ribonucleoprotein U Histone deacetylase 1 Histone deacetylase 2 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase PRDM16 Lipid transferase CIDEA Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Mitochondrial brown fat uncoupling protein 1 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Nuclear receptor coactivator 1 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Peroxisome proliferator-activated receptor gamma Retinoic acid receptor RXR-alpha Transcription factor COE2 Transcriptional repressor p66-alpha Transcriptional repressor p66-beta Type II iodothyronine deiodinase Very long chain fatty acid elongase 3 Zinc finger protein 423	O60543 O94776 O95983 P18075 P19793 P24310 P25874 P37231 Q00839 Q07869 Q09028 Q12873 Q13330 Q13485 Q13547 Q14839 Q15788 Q15797 Q16576 Q2M1K9 Q86YN6 Q86YP4 Q8WXI9 Q92769 Q92813 Q9BTC8 Q9HAK2 Q9HAZ2 Q9HB03 Q9UBK2	BHLHE74 BMP7 BSP1 C1orf199 CHD3 CHD4 CIDEA CIG30 COE2 COX7A1 COX7AH DIO2 DPC4 EBF2 ELOVL3 GATAD2A GATAD2B HDAC1 HDAC2 HNRNPU HNRPU ITDI2 KIAA0760 KIAA1150 KIAA1266 KIAA1675 LEM6 MADH1 MADH4 MADR1 MBD3 MEL1 MTA1 MTA1L1 MTA2 MTA3 NCOA1 NPHP14 NR1C1 NR1C3 NR2B1 OAZ OP1 PERC PFM13 PGC1 PGC1A PGC1B PID PPAR PPARA PPARG PPARGC1 PPARGC1A PPARGC1B PRDM16 RBAP46 RBAP48 RBBP4 RBBP7 RPD3L1 RXRA SAFA SLC25A7 SMAD1 SMAD4 SRC1 TXDI2 U21.1 UCP UCP1 ZNF423	Homo sapiens (human)
Signaling by Retinoic Acid	Cellular retinoic acid-binding protein 2 Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Fatty acid-binding protein 5 Peroxisome proliferator-activated receptor delta Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Retinoic acid receptor RXR-gamma Retinoic acid receptor alpha Retinoic acid receptor beta Retinoic acid receptor gamma [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	O00330 P08559 P09622 P10276 P10515 P10826 P11177 P13631 P19793 P28702 P29373 P29803 P48443 Q01469 Q03181 Q15118 Q15119 Q15120 Q16654	CRABP2 DLAT DLD DLTA FABP5 GCSL HAP LAD NR1B1 NR1B2 NR1B3 NR1C2 NR2B1 NR2B2 NR2B3 PDHA1 PDHA2 PDHAL PDHB PDHK1 PDHK2 PDHK3 PDHK4 PDHX PDK1 PDK2 PDK3 PDK4 PDX1 PHE1A PHE1B PHE3 PPARB PPARD RARA RARB RARG RXRA RXRB RXRG	Homo sapiens (human)
Formation of HIV elongation complex in the absence of HIV Tat	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 O60583 O75909 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P50613 P50750 P51946 P51948 P52298 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q09161 Q13888 Q13889 Q14241 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92759 Q9H3P2 Q9Y5B0 Q9Y5B9	BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CCNK CCNT1 CCNT2 CDC2L4 CDK7 CDK9 CDKN7 COBRA1 CPR4 CTDP1 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S KIAA1182 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC	Homo sapiens (human)
Vitamin D (calciferol) metabolism	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial Cubilin E3 SUMO-protein ligase PIAS4 Legumain Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 2 Vitamin D 25-hydroxylase Vitamin D-binding protein Vitamin D3 receptor	O15528 O60494 P02774 P11473 P61956 P63279 P98164 Q07973 Q5SW96 Q6VVX0 Q8N2W9 Q99538	ARH CUBN CYP1ALPHA CYP24 CYP24A1 CYP27B CYP27B1 CYP2R1 GC IFCR LDLRAP1 LGMN LRP2 NR1I1 PIAS4 PIASG PRSC1 SMT3B SMT3H2 SUMO2 UBC9 UBCE9 UBE2I VDR	Homo sapiens (human)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O00762 O14818 O43242 O43684 O60566 P06493 P0CG47 P0CG48 P17980 P20248 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30260 P35998 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P60006 P60896 P60900 P62191 P62195 P62333 P62979 P62987 P78396 Q12834 Q13042 Q13200 Q13257 Q15008 Q16186 Q16763 Q8NHZ8 Q96DE5 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13 Q9UNM6	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C7orf76 C9orf17 CCN1 CCNA CCNA1 CCNA2 CDC16 CDC2 CDC20 CDC23 CDC26 CDC27 CDC28A CDK1 CDKN1 CENP-27 D0S1430E D17S978E DSS1 E2EPF GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 KIAA1406 LMPX LMPY MAD2 MAD2L1 MAD3L MB1 MIP224 MOV34L MSS1 NU P34CDC2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEM1 SFT SHFDG1 SHFM1 SSK1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Z	Homo sapiens (human)
RUNX2 regulates genes involved in cell migration	Collagenase 3 Core-binding factor subunit beta Integrin alpha-5 Integrin beta-like protein 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	O95965 P08648 P31749 P31751 P45452 Q13951 Q9Y243	AKT1 AKT2 AKT3 CBFB FNRA ITGA5 ITGBL1 MMP13 OSCP PKB PKBG RAC TIED	Homo sapiens (human)
Pyrimidine catabolism	5'(3')-deoxyribonucleotidase, cytosolic type 5'(3')-deoxyribonucleotidase, mitochondrial 5'-nucleotidase Alanine--glyoxylate aminotransferase 2, mitochondrial Beta-ureidopropionase Cytosolic 5'-nucleotidase 1A Dihydropyrimidinase Dihydropyrimidine dehydrogenase [NADP(+)] Thymidine phosphorylase Uridine phosphorylase 1 Uridine phosphorylase 2	O95045 P19971 P21589 Q12882 Q14117 Q16831 Q8TCD5 Q9BXI3 Q9BYV1 Q9NPB1 Q9UBR1	AGT2 AGXT2 BUP1 DNT1 DNT2 DPYD DPYS ECGF1 NT5 NT5C NT5C1A NT5E NT5M NTE TYMP UMPH2 UP UPB1 UPP1 UPP2	Homo sapiens (human)
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Docking protein 1 E3 ubiquitin-protein ligase CBL Polyubiquitin-B Polyubiquitin-C Protein-tyrosine kinase 6 RAC-alpha serine/threonine-protein kinase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P22681 P31749 P62979 P62987 Q13882 Q96P48 Q99704	AKT1 ARAP1 BRK CBL CBL2 CENTD2 DOK1 KIAA0782 PKB PTK6 RAC RNF55 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Integrin signaling	3-phosphoinositide-dependent protein kinase 1 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Ras-related protein Rap-1A Ras-related protein Rap-1b SHC-transforming protein 1 Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 1 von Willebrand factor	O15530 O95267 O95398 P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P18031 P29353 P31749 P41240 P43405 P61224 P62834 Q05397 Q7LDG7 Q7Z5R6 Q8WZA2 Q9Y490	AKT1 APBB1IP CDC25L CGEF1 CGEF2 CSK EPAC EPAC1 EPAC2 F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 MCG7 PDK1 PDPK1 PKB PREL1 PTK2 PTP1B PTPN1 RAC RAP1A RAP1B RAPGEF3 RAPGEF4 RARP1 RASGRP RASGRP1 RASGRP2 RIAM SHC SHC1 SHCA SRC SRC1 SYK TLN TLN1 VWF	Homo sapiens (human)
Beta oxidation of palmitoyl-CoA to myristoyl-CoA	Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	P40939 P49748 P55084	ACADVL HADH HADHA HADHB VLCAD	Homo sapiens (human)
PLC-gamma1 signalling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629 P19174	MTC NGF NGFB NTRK1 PLC1 PLCG1 TRK TRKA	Homo sapiens (human)
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	ATPase MORC2 Activating transcription factor 7-interacting protein 1 Exosome RNA helicase MTR4 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Histone-lysine N-methyltransferase SETDB1 M-phase phosphoprotein 8 Periphilin-1 Protein TASOR RNA-binding protein 7 Zinc finger CCHC domain-containing protein 8	O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P33778 P42285 P57053 P58876 P62805 P62807 P68431 P84243 Q15047 Q16777 Q16778 Q6FI13 Q6NZY4 Q6VMQ6 Q71DI3 Q71UI9 Q8N257 Q8NEY8 Q93077 Q93079 Q96A08 Q96KQ7 Q99549 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H9B1 Q9UK61 Q9Y580 Q9Y6X9	ATF7IP BAT8 C3orf63 C6orf30 DOB1 EHMT1 EHMT2 ESET EUHMTASE1 FAM208A G9A GLP H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 KIAA0052 KIAA0067 KIAA0852 KIAA1105 KIAA1876 KMT1C KMT1D KMT1E MCAF MCAF1 MORC2 MPHOSPH8 MPP8 MTR4 MTREX NG36 PPHLN1 RBM7 SETDB1 SKIV2L2 TASOR TSH2B ZCCHC8 ZCWCC1	Homo sapiens (human)
Mtb iron assimilation by chelation	Bacterioferritin BfrA Bacterioferritin BfrB Lactotransferrin Mycobactin import ATP-binding/permease protein IrtA Mycobactin import ATP-binding/permease protein IrtB Uncharacterized protein Rv2895c	P02788 P9WL31 P9WNE5 P9WPQ9 P9WQJ7 P9WQJ9	GIG12 LF LTF Rv2895c bfr bfrA bfrB ftn irtA irtB	Homo sapiens (human)
Chemokine receptors bind chemokines	Atypical chemokine receptor 2 Atypical chemokine receptor 3 Atypical chemokine receptor 4 C-C chemokine receptor type 10 C-C chemokine receptor type 1 C-C chemokine receptor type 2 C-C chemokine receptor type 3 C-C chemokine receptor type 4 C-C chemokine receptor type 5 C-C chemokine receptor type 6 C-C chemokine receptor type 7 C-C chemokine receptor type 8 C-C chemokine receptor type 9 C-C chemokine receptor-like 2 C-C motif chemokine 13 C-C motif chemokine 16 C-C motif chemokine 17 C-C motif chemokine 19 C-C motif chemokine 1 C-C motif chemokine 20 C-C motif chemokine 21 C-C motif chemokine 22 C-C motif chemokine 25 C-C motif chemokine 27 C-C motif chemokine 28 C-C motif chemokine 2 C-C motif chemokine 3-like 1 C-C motif chemokine 3 C-C motif chemokine 4 C-C motif chemokine 5 C-C motif chemokine 7 C-X-C chemokine receptor type 1 C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 3 C-X-C chemokine receptor type 4 C-X-C chemokine receptor type 5 C-X-C chemokine receptor type 6 C-X-C motif chemokine 10 C-X-C motif chemokine 11 C-X-C motif chemokine 13 C-X-C motif chemokine 16 C-X-C motif chemokine 2 C-X-C motif chemokine 3 C-X-C motif chemokine 5 C-X-C motif chemokine 6 C-X-C motif chemokine 9 CX3C chemokine receptor 1 Chemokine XC receptor 1 Cytokine SCM-1 beta Eotaxin Fractalkine Growth-regulated alpha protein Interleukin-8 Lymphotactin Platelet basic protein Platelet factor 4 Stromal cell-derived factor 1	O00421 O00574 O00585 O00590 O00626 O14625 O15444 O15467 O43927 P02775 P02776 P02778 P09341 P10145 P10147 P13236 P13500 P13501 P16619 P19875 P19876 P22362 P25024 P25025 P25106 P32246 P32248 P32302 P41597 P42830 P46092 P46094 P47992 P48061 P49238 P49682 P51671 P51677 P51679 P51681 P51684 P51685 P51686 P61073 P78423 P78556 P80098 P80162 Q07325 Q92583 Q99616 Q99731 Q9H2A7 Q9NPB9 Q9NRJ3 Q9UBD3 Q9Y4X3	ACKR2 ACKR3 ACKR4 BCA1 BLC BLR1 BONZO CCBP2 CCL1 CCL11 CCL13 CCL16 CCL17 CCL19 CCL2 CCL20 CCL21 CCL22 CCL25 CCL27 CCL28 CCL3 CCL3L1 CCL3L3 CCL4 CCL5 CCL7 CCR1 CCR10 CCR11 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL1 CCRL2 CCXCR1 CKRL1 CKRL3 CKRX CMK CMKAR1 CMKBR1 CMKBR2 CMKBR3 CMKBR4 CMKBR5 CMKBR6 CMKBR7 CMKBR8 CMKBR9 CMKBRL1 CMKBRL2 CMKOR1 CMKR1 CRAM CTAP3 CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL16 CXCL2 CXCL3 CXCL4 CXCL5 CXCL6 CXCL7 CXCL8 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 D17S136E D17S1718 D6 EBI1 ELC ENA78 EVI1 FKN G0S19-1 G0S19-2 GCP2 GPR13 GPR159 GPR2 GPR28 GPR29 GPR5 GPR9 GRO GRO1 GRO2 GRO3 GROA GROB GROG HCR IL8 IL8RA IL8RB ILC ILINCK INP10 ITAC LAG1 LARC LTN MCP1 MCP3 MCP4 MDC MDR15 MGSA MIG MIP1A MIP1B MIP2A MIP3A MIP3B NCC1 NCC4 NTT PF4 PPBP RDC1 SCYA1 SCYA11 SCYA13 SCYA16 SCYA17 SCYA19 SCYA2 SCYA20 SCYA21 SCYA22 SCYA25 SCYA27 SCYA28 SCYA3 SCYA3L1 SCYA4 SCYA5 SCYA6 SCYA7 SCYAR1 SCYB1 SCYB10 SCYB11 SCYB13 SCYB16 SCYB2 SCYB3 SCYB4 SCYB5 SCYB6 SCYB7 SCYB9 SCYB9B SCYC1 SCYC2 SCYD1 SDF1 SDF1A SDF1B SRPSOX STRL22 STRL33 TARC TECK TGB1 THBGB1 TYMSTR VSHK1 XCL1 XCL2 XCR1	Homo sapiens (human)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	DNA polymerase beta DNA repair nuclease/redox regulator APEX1	P06746 P27695	APE APE1 APEX APEX1 APX HAP1 POLB REF1	Homo sapiens (human)
MPS VI - Maroteaux-Lamy syndrome	Arylsulfatase B	P15848	ARSB	Homo sapiens (human)
Defective SLC12A3 causes Gitelman syndrome (GS)	Solute carrier family 12 member 3	P55017	NCC SLC12A3 TSC	Homo sapiens (human)
Resistance of ERBB2 KD mutants to afatinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2	Homo sapiens (human)

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