GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **2074** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism
Termination of O-glycan biosynthesis	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1	P15907 P15941 P98088 Q02505 Q02817 Q11201 Q11203 Q11206 Q16842 Q5SSG8 Q685J3 Q6W4X9 Q7Z5P9 Q8N307 Q8N387 Q8NDV1 Q8TAX7 Q8WXI7 Q96DR8 Q99102 Q9H195 Q9H3R2 Q9H4F1 Q9HC84 Q9UJ37 Q9UKN1	C6orf205 CA125 CGS23 DRCC1 KIAA1359 MG2 MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 NANTA3 PUM RECC SBEM SIAT1 SIAT3C SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SIAT7B SIAT7C SIAT7D SIATL1 SMUC ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST6GAL1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 STHM STZ	Homo sapiens (human)
Terminal pathway of complement	Clusterin Complement C5 Complement component C6 Complement component C7 Complement component C8 alpha chain Complement component C8 beta chain Complement component C8 gamma chain Complement component C9	P01031 P02748 P07357 P07358 P07360 P10643 P10909 P13671	APOJ C5 C6 C7 C8A C8B C8G C9 CLI CLU CPAMD4 KUB1	Homo sapiens (human)
Telomere Extension By Telomerase	ATP-dependent DNA helicase PIF1 Adrenocortical dysplasia protein homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 Protection of telomeres protein 1 Protein SHQ1 homolog Regulator of telomere elongation helicase 1 RuvB-like 1 RuvB-like 2 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 3 TERF1-interacting nuclear factor 2 Telomerase Cajal body protein 1 Telomerase reverse transcriptase Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O00743 O14746 O15084 O60832 P20248 P24941 P54274 P78396 Q15554 Q5H9R7 Q6PI26 Q96AP0 Q9BSI4 Q9BUR4 Q9H611 Q9NPE3 Q9NUX5 Q9NX24 Q9NY12 Q9NYB0 Q9NZ71 Q9Y230 Q9Y265	ACD ANKRD28 C11orf23 C15orf20 C20orf41 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 DKC1 DRIP5 EST2 GAR1 INO80H INO80J KIAA0379 KIAA1088 KIAA1558 NHL NHP2 NMP238 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 PIF1 PIN2 PIP1 POT1 PP6R3 PPP6 PPP6C PPP6R3 PTOP RAP1 RTEL1 RUVBL1 RUVBL2 SAPL SAPS3 SHQ1 TCAB1 TCS1 TERF1 TERF2 TERF2IP TERT TIN2 TINF2 TINT1 TIP48 TIP49 TIP49A TIP49B TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TRT WDR79 WRAP53	Homo sapiens (human)
Telomere C-strand synthesis initiation	Adrenocortical dysplasia protein homolog CST complex subunit CTC1 CST complex subunit STN1 CST complex subunit TEN1 DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA primase large subunit DNA primase small subunit Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P09884 P49642 P49643 P54274 Q14181 Q15554 Q2NKJ3 Q86WV5 Q96AP0 Q9BSI4 Q9H668 Q9NUX5 Q9NYB0	ACD C17orf106 C17orf68 CTC1 DRIP5 OBFC1 PIN2 PIP1 POLA POLA1 POLA2 POT1 PRIM1 PRIM2 PRIM2A PTOP RAP1 STN1 TEN1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2	Homo sapiens (human)
Telomere C-strand (Lagging Strand) Synthesis	Adrenocortical dysplasia protein homolog DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Proliferating cell nuclear antigen Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P28340 P49005 P54274 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD DRIP5 KIAA0039 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2	Homo sapiens (human)
Tat-mediated elongation of the HIV-1 transcript	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-T1 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Protein Tat RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 P04608 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P50613 P50750 P51946 P51948 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q13888 Q13889 Q14241 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92759 Q9H3P2 Q9Y5B0 Q9Y5B9	BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CCNH CCNT1 CDC2L4 CDK7 CDK9 CDKN7 COBRA1 CTDP1 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S KIAA1182 MAT1 MNAT1 MO15 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC tat	Homo sapiens (human)
Tat-mediated HIV elongation arrest and recovery	Cyclin-T1 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Protein Tat RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 P04608 P13984 P18615 P19387 P19388 P23193 P24928 P30876 P35269 P36954 P50750 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q14241 Q15369 Q15370 Q8IXH7 Q8IYF1 Q8WX92 Q9H3P2 Q9Y5B0 Q9Y5B9	C19orf17 CCNT1 CDC2L4 CDK9 COBRA1 CTDP1 ELL ELOA ELOA2 ELOB ELOC FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2S KIAA1182 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RPB7 SPT4H SPT5 SPT5H SSRP1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L WHSC2 tat	Homo sapiens (human)
Tandem pore domain halothane-inhibited K+ channel (THIK)	Potassium channel subfamily K member 13	Q9HB14	KCNK13	Homo sapiens (human)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member 1 Potassium channel subfamily K member 6 Potassium channel subfamily K member 7	O00180 Q9Y257 Q9Y2U2	HOHO1 KCNK1 KCNK6 KCNK7 KCNO1 TOSS TWIK1 TWIK2	Homo sapiens (human)
Tachykinin receptors bind tachykinins	Neuromedin-K receptor Protachykinin-1 Substance-K receptor Substance-P receptor Tachykinin-3	P20366 P21452 P25103 P29371 Q9UHF0	NK1R NK2R NK3R NKA NKNA NKNAR NKNB TAC1 TAC1R TAC2 TAC2R TAC3 TAC3R TACR1 TACR2 TACR3	Homo sapiens (human)
TYSND1 cleaves peroxisomal proteins	3-ketoacyl-CoA thiolase, peroxisomal Alkyldihydroxyacetonephosphate synthase, peroxisomal Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal leader peptide-processing protease Peroxisomal multifunctional enzyme type 2 Phytanoyl-CoA dioxygenase, peroxisomal Sterol carrier protein 2	O00116 O14832 P09110 P22307 P51659 Q15067 Q2T9J0	ACAA ACAA1 ACOX ACOX1 AGPS EDH17B4 HSD17B4 PAHX PHYH PTHIO SCP2 SDR8C1 TYSND1	Homo sapiens (human)
TWIK-releated acid-sensitive K+ channel (TASK)	Potassium channel subfamily K member 3 Potassium channel subfamily K member 9	O14649 Q9NPC2	KCNK3 KCNK9 TASK TASK1 TASK3	Homo sapiens (human)
TWIK-related spinal cord K+ channel (TRESK)	Potassium channel subfamily K member 18	Q7Z418	KCNK18 TRESK TRIK	Homo sapiens (human)
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium channel subfamily K member 16 Potassium channel subfamily K member 17	Q96T54 Q96T55	KCNK16 KCNK17 TALK1 TALK2 TASK4	Homo sapiens (human)
TWIK related potassium channel (TREK)	Potassium channel subfamily K member 10 Potassium channel subfamily K member 2 Potassium channel subfamily K member 4	O95069 P57789 Q9NYG8	KCNK10 KCNK2 KCNK4 TRAAK TREK TREK1 TREK2	Homo sapiens (human)
TRP channels	Mucolipin-1 Mucolipin-2 Mucolipin-3 Short transient receptor potential channel 1 Short transient receptor potential channel 3 Short transient receptor potential channel 4-associated protein Short transient receptor potential channel 4 Short transient receptor potential channel 5 Short transient receptor potential channel 6 Short transient receptor potential channel 7 Transient receptor potential cation channel subfamily A member 1 Transient receptor potential cation channel subfamily M member 1 Transient receptor potential cation channel subfamily M member 2 Transient receptor potential cation channel subfamily M member 3 Transient receptor potential cation channel subfamily M member 4 Transient receptor potential cation channel subfamily M member 5 Transient receptor potential cation channel subfamily M member 6 Transient receptor potential cation channel subfamily M member 7 Transient receptor potential cation channel subfamily M member 8 Transient receptor potential cation channel subfamily V member 1 Transient receptor potential cation channel subfamily V member 2 Transient receptor potential cation channel subfamily V member 3 Transient receptor potential cation channel subfamily V member 4 Transient receptor potential cation channel subfamily V member 5 Transient receptor potential cation channel subfamily V member 6	O75762 O94759 P48995 Q13507 Q7Z2W7 Q7Z4N2 Q8IZK6 Q8NER1 Q8NET8 Q8TD43 Q8TDD5 Q8TEL6 Q96QT4 Q9BX84 Q9GZU1 Q9H1D0 Q9HBA0 Q9HCF6 Q9HCX4 Q9NQA5 Q9NZQ8 Q9UBN4 Q9UL62 Q9Y210 Q9Y5S1	ANKTM1 C20orf188 CHAK1 CHAK2 ECAC1 ECAC2 EREG1 KIAA1616 KNP3 LTRPC1 LTRPC2 LTRPC3 LTRPC4 LTRPC5 LTRPC6 LTRPC7 MCOLN1 MCOLN2 MCOLN3 ML4 MLSN MLSN1 MTR1 TRP1 TRP3 TRP5 TRP6 TRP7 TRPA1 TRPC1 TRPC3 TRPC4 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML1 TRPP8 TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6 TRRP4AP VR1 VRL VRL2 VROAC	Homo sapiens (human)
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629	MTC NGF NGFB NTRK1 TRK TRKA	Homo sapiens (human)
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q13158 Q13546 Q14790 Q86XR7 Q8IUC6 Q9Y572 Q9Y6Y9	CASP8 CD14 ESOP1 FADD LY96 MCH5 MD2 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF	Homo sapiens (human)
TRAIL signaling	CASP8 and FADD-like apoptosis regulator Caspase-10 Caspase-8 FAS-associated death domain protein Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10D	O00220 O14763 O15519 P50591 Q13158 Q14790 Q92851 Q9UBN6	APO2 APO2L CASH CASP10 CASP8 CASP8AP1 CFLAR CLARP DCR2 DR4 DR5 FADD KILLER MCH4 MCH5 MORT1 MRIT TNFRSF10A TNFRSF10B TNFRSF10D TNFSF10 TRAIL TRAILR1 TRAILR2 TRAILR4 TRICK2 TRUNDD ZTNFR9	Homo sapiens (human)
TRAF6-mediated induction of TAK1 complex within TLR4 complex	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O43187 O43318 P08571 P0CG47 P0CG48 P62979 P62987 Q15750 Q86XR7 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3 Q9Y6Y9	CD14 ESOP1 IRAK2 KIAA0733 LY96 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MD2 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 1 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 7 Toll-like receptor 9	O43187 P51617 Q13233 Q99836 Q9BQ95 Q9NR96 Q9NWZ3 Q9NYK1 Q9Y4K3	ECSIT IRAK IRAK1 IRAK2 IRAK4 MAP3K1 MAPKKK1 MEKK MEKK1 MYD88 RNF85 TLR7 TLR9 TRAF6	Homo sapiens (human)
TRAF6 mediated NF-kB activation	Advanced glycosylation end product-specific receptor Amyloid-beta precursor protein Antiviral innate immune response receptor RIG-I E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Mitogen-activated protein kinase kinase kinase 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 1 NF-kappa-B inhibitor-interacting Ras-like protein 2 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Protein S100-A12 Protein S100-B Serum amyloid A-1 protein TNF receptor-associated factor 2 TNF receptor-associated factor 6 Transcription factor p65	O14920 O15111 O95786 P04271 P05067 P09429 P0DJI8 P19838 P25963 P80511 Q00653 Q04206 Q12933 Q13233 Q14258 Q15109 Q15653 Q7Z434 Q8IUD6 Q9BYX4 Q9C037 Q9NYR9 Q9NYS0 Q9Y4K3 Q9Y6K9	A4 AD1 AGER APP CHUK DDX58 EFP FIP3 HMG1 HMGB1 IFIH1 IKBA IKBB IKBKB IKBKG IKKA IKKB IPS1 KBRAS1 KBRAS2 KIAA1271 LYT10 MAD3 MAP3K1 MAPKKK1 MAVS MDA5 MEKK MEKK1 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA NFKBIB NKIRAS1 NKIRAS2 RAGE RELA RH116 RIGI RNF135 RNF147 RNF85 RNF87 S100A12 S100B SAA1 TCF16 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 TRIP9 VISA ZNF147	Homo sapiens (human)
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	Interferon regulatory factor 7 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 7 Toll-like receptor 9 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	P51617 P61088 Q13404 Q92985 Q99836 Q9NR96 Q9NWZ3 Q9NYK1 Q9Y4K3	BLU CROC1 IRAK IRAK1 IRAK4 IRF7 MYD88 RNF85 TLR7 TLR9 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
TRAF6 mediated IRF7 activation	Antiviral innate immune response receptor RIG-I CREB-binding protein E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Histone acetyltransferase p300 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon beta Interferon regulatory factor 3 Interferon regulatory factor 7 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Serine/threonine-protein kinase TBK1 Suppressor of IKBKE 1 TNF receptor-associated factor 2 TNF receptor-associated factor 6 TRAF family member-associated NF-kappa-B activator	O95786 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P32881 Q09472 Q12933 Q14164 Q14258 Q14653 Q7Z434 Q8IUD6 Q92793 Q92844 Q92985 Q9BRV8 Q9BYX4 Q9C037 Q9UHD2 Q9Y4K3	CBP CREBBP DDX58 EFP EP300 IFB IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB IFNB1 IKBKE IKKE IKKI IPS1 IRF3 IRF7 ITRAF KIAA0151 KIAA1271 MAVS MDA5 NAK P300 RH116 RIGI RNF135 RNF147 RNF85 RNF87 SIKE SIKE1 TANK TBK1 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 VISA ZNF147	Homo sapiens (human)
TRAF3-dependent IRF activation pathway	Antiviral innate immune response receptor RIG-I CREB-binding protein E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Histone acetyltransferase p300 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon beta Interferon regulatory factor 3 Interferon regulatory factor 7 Interferon-induced helicase C domain-containing protein 1 Membrane protein Mitochondrial antiviral-signaling protein Non-structural protein 1 Serine/threonine-protein kinase TBK1 Suppressor of IKBKE 1 TNF receptor-associated factor 3	O95786 P01574 P0DOE9 P0DTC5 Q09472 Q13114 Q14164 Q14258 Q14653 Q7Z434 Q8IUD6 Q92793 Q92985 Q9BRV8 Q9BYX4 Q9C037 Q9UHD2	1C CAP-1 CBP CRAF1 CREBBP DDX58 EFP EP300 IFB IFIH1 IFNB IFNB1 IKBKE IKKE IKKI IPS1 IRF3 IRF7 KIAA0151 KIAA1271 M MAVS MDA5 NAK NS1 P300 RH116 RIGI RNF135 RNF147 RNF87 SIKE SIKE1 TBK1 TRAF3 TRAFAMN TRIM25 TRIM4 VISA ZNF147	Homo sapiens (human)

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