GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	October 28, 2022
DisGeNET	June 29,2021
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID	Disease Name	Gene Symbol	Gene ID ▲
DOID:4947	cholangiocarcinoma	AADAC ALOX5 ATG26 Alox5 Alox5 FHIT HDA1 HDAC6 Hdac6 IDH2 N NCAM1 OGG1 OGG1 Ogg1 Ogg1 Ogg1 PTGS2 STS UGT1A9 Ugt1a10 Ugt1a7c Ugt1a7c Ugt1a8 Ugt1a8 Ugt1a9 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35B1 Ugt35C1 Ugt35E2 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A3 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B2 hda-6 ugt-61 ugt1a1 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7	10013 100379286 100384891 100384896 100384901 100489505 11689 13 15185 154516 177316 18294 185500 2272 240 25290 301595 31293 31806 3418 35105 35137 35138 35139 394430 394432 394434 396552 40079 406731 412 41333 41334 41574 42538 4684 4968 53501 53502 53503 53506 53507 53511 53512 53583 54600 5743 641488 81528 850886 854942 855710
DOID:14330	Parkinson's disease	ACHE ADH7 ANXA5 CALR3 CALR CYP1A1 CYP2E1 DNM1 DNM1L Dnm1l Dnm1l EPHX1 EPHX2 Ephx1 Ephx1 GBA1 GEM1 GPI Gba HDA1 HDAC6 HSPA8 Hdac6 Hspa8 Hspa8 INP51 INP52 INP53 INSR LRRK2 Lrrk2 Miro NSF Nsf2 Nsf Nsf OGG1 OGG1 Ogg1 Ogg1 Ogg1 PGK1 PGK1 PGK2 PISD PLA2G6 PRKAA2 Pla2g6 Pla2g6 PolG1 RHOT1 RHOT2 Rhot1 Rhot2 Rhot2 SARM1 SDHA SNF1 SSC1 SYNJ1 SYNJ2 Synj1 Synj2 Synj2 TPPP Tppp Tppp adh1c comt daf-2 dnm1l gba-1 gba-2 gba-3 gba-4 hda-6 miro-1 nsf-1 rhot1a rhot2 rhot2 unc-26	10013 100486839 10059 11076 114114 120892 125972 131 13849 14466 15185 1543 15481 1571 173574 175410 177238 177314 177316 178284 178535 18195 18294 183155 2052 2053 20975 214952 23098 23761 24468 25315 2629 266842 2821 287156 308 31806 327143 3312 34792 360426 361466 3643 393896 41694 42845 43 448378 47091 4905 4968 5230 5232 53357 55288 5563 557574 59040 60355 6389 66725 72948 74006 811 81528 8398 84018 850370 850686 851249 852088 85238 853503 854276 854815 854942 855618 855710 8867 8871 89941
DOID:0050770	polycystic liver disease	ALG8 ALG8 Alg8 Alg8 GANAB Ganab HDA1 HDAC6 Hdac6 PKD1 ROT2 alg8.S alg8 alg8 algn-8 hda-6 xit	10013 14376 15185 174542 177316 23193 293129 31623 327601 381903 431849 5310 548388 79053 852530 854233 855710
DOID:8991	cervix uteri carcinoma in situ	HDA1 HDAC1 HDAC1 HDAC2 HDAC6 Hdac1 Hdac1 Hdac2 Hdac6 MEST PTEN PTGS2 RPD3 TEP1 VCP hda-1 hda-6 hdac1.L	10013 15182 15185 177316 179959 297893 3065 3066 38565 397868 4232 433759 5728 5743 7415 855386 855595 855710
DOID:0112106	chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia	HDA1 HDAC6 Hdac6 hda-6	10013 15185 177316 855710
DOID:9744	type 1 diabetes mellitus	ACE ACHE ALDH2 ATG26 CD14 CD38 CHI3L1 CLEC16A CTS2 CYP27B1 CYP2E1 CYP2R1 Cd38 Cd38 FUCA1 Fuca1 Fuca1 Fuca G6PC2 G6PD G6pc2 GAD2 GPX3 HDAC1 HDAC1 HDAC2 HDAC3 HOS2 HSD11B2 Hdac1 Hdac1 Hdac2 Hdac3 Hdac3 ICAM1 IGF2R IL1R1 Idgf1 Idgf2 Idgf3 Idgf4 Il1r1 LGALS3 LIPC Lerp Lipc NCAM1 PON1 Pon1 Pon1 RAN RPD3 Ran Ran SELE SELL UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35B1 Ugt35C1 Ugt35E2 Ugt36A1 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A2 Ugt37A3 Ugt37B1 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B1 Ugt49B2 VCAM1 XYLT1 Xylt1 cht-1 hda-1 hda-2 hdac1.L hdac3.S hdac3 hdac3 oxt ran.L ran.S ran ran sqv-6 ugt-62 ugt1a1 ugt1a6 ugt1a6 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7 xylt1.L xylt1.S xylt1 xylt1	100135191 100145490 100379286 100384891 100384896 100384901 100489505 108703114 108716335 1116 116406461 120227 12494 14378 15182 15183 15450 1571 1594 16177 1636 174285 175591 179959 180628 18979 190099 19384 217 23274 233781 24375 24861 2517 2539 25668 2572 2878 297893 30572 3065 3066 31926 3291 3383 3482 34978 34979 34981 35105 35137 35138 35139 3554 37420 3772574 379874 38288 38565 393965 394436 3958 397868 3990 40079 406731 41333 41334 41573 41574 42538 43 432017 43223 433759 44058 444363 448091 4684 53501 53502 53503 53506 53507 53511 53512 53583 53584 5444 54658 549637 560951 57818 5901 6401 6402 64131 641488 71665 7412 84024 84509 84578 850886 851977 852681 855386 8841 929 952
DOID:1612	breast cancer	AADAC ACACA ACE ACSL3 AKR1A1 AKR1B10 ALDH1A3 ALOX12 ANXA7 ATG26 Alox12 BST2 CACNA2D3 CALR CBR1 CD55 CDH13 CHI3L1 CHKA CTS2 CYB5R3 CYP17A1 CYP19A1 CYP1A1 CYP1A2 CYP1B1 CYP2C19 CYP3A4 CYP7B1 DPM1 DPP1 EIF2S3 FASN FHIT GPX1 GPX3 HDAC1 HK2 HMMR HPGDS HPSE HRAS HS3ST2 HYAL2 ICAM1 INPP4B INSR Idgf1 Idgf2 Idgf3 Idgf4 KL KRAS Kras Kras MBD4 MCAT NEU1 NT5E OGDHL OGG1 OGG1 Ogg1 Ogg1 Ogg1 PEMT PIK3CA PIK3CB PIK3CD PIK3CG PKM PLA2R1 PLC1 PLCD1 PLCG1 PLPP4 PON1 PTEN PTGES3 PTGS1 PTGS2 Plcg1 Plcg1 Plpp4 Pon1 Pon1 RAC1 RAD50 RAD50 RECK RERG RHO1 RHO2 RHOA Rac1 Rac1 Rad50 Ras85D Rerg Rhoa Rhoa Rrp1 SHMT1 SNF1 STS SULT1E1 TEP1 TNFRSF10C UGCG UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35B1 Ugt35C1 Ugt35E2 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A3 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B2 YTA7 cht-1 daf-2 krasl plc-3 rad50 ugt-61 ugt1a1 ugt1a6 ugt1a6 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7	100135191 100379286 100384891 100384896 100384901 100489505 100494334 10111 1012 10327 10400 10728 10855 1116 1119 116406461 11684 117273 11848 13 1543 1544 1545 1557 1576 1586 1588 1604 1636 16653 1727 174586 175410 180628 18294 185500 18803 18979 19353 196051 1968 2181 2194 220 2272 22925 232441 239 24525 24861 25738 27306 27349 2876 2878 3065 3099 31 310 3161 31806 31926 3265 33500 3383 34978 34979 34981 35105 35137 35138 35139 363875 3643 37564 381925 3845 387 394436 40079 406731 41140 412 41333 41334 41574 42538 4758 4907 4968 5290 5291 5293 5294 5315 5333 5335 53501 53502 53503 53506 53507 53511 53512 53583 5444 54658 55753 55799 57016 5728 5742 5743 5879 64012 641488 6470 6783 684 7357 811 81528 84024 8434 85004 850886 851878 851977 852088 853186 854768 854942 855471 855595 855634 855860 856294 856313 8692 8794 8821 8930 9365 9420 9956
DOID:2394	ovarian cancer	ABHD8 ANXA7 ATG26 CALR CDH13 CHI3L1 CTS2 CYP19A1 DMD GBGT1 HDAC3 HOS2 HRAS HS3ST2 Hdac3 Hdac3 ICAM1 IGF2R Idgf1 Idgf2 Idgf3 Idgf4 MRC1 MSLN OGG1 OGG1 OPCML OVCA2 Ogg1 Ogg1 Ogg1 Ovca2 PIK3CA POL2 POLE PRSS8 PTEN PTGS1 PolE1 Pole Rrp1 SHMT1 STS TEP1 TNFRSF10C TUSC3 UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35B1 Ugt35C1 Ugt35E2 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A3 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B2 cht-1 hda-2 hdac3.S hdac3 hdac3 ovca2 ugt-61 ugt1a1 ugt1a6 ugt1a6 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7	100135191 100379286 100384891 100384896 100384901 100489505 1012 10232 1116 116406461 124641 15183 1588 174285 1756 180628 18294 185500 18973 246257 24861 26301 310 31806 31926 3265 33500 3383 3482 34978 34979 34981 35105 35137 35138 35139 393965 394436 40079 406731 412 41333 41334 41574 42538 42758 432017 4360 4968 4978 5290 53501 53502 53503 53506 53507 53511 53512 53583 5426 54658 549637 553576 5652 5728 5742 641488 6470 79575 7991 811 81528 84578 850886 851977 852681 854942 855459 855595 8794 8841 9956
DOID:1380	endometrial cancer	ADARB1 ATG26 BST2 CDH13 CHI3L1 CTS2 CYP17A1 CYP19A1 CYP1A1 CYP1A2 Idgf1 Idgf2 Idgf3 Idgf4 KRAS L1CAM MRC1 N PGM1 PGM2 PIK3CA PIK3CB PIK3CD POL2 POLE PTEN PolE1 Pole Rrp1 SULT1E1 TEP1 UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35B1 Ugt35C1 Ugt35E2 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A3 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B2 cht-1 ugt-61 ugt1a1 ugt1a6 ugt1a6 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7	100135191 100379286 100384891 100384896 100384901 100489505 1012 104 1116 116406461 1543 1544 1586 1588 180628 185500 18973 24861 31293 31926 33500 34978 34979 34981 35105 35137 35138 35139 3845 3897 394436 40079 406731 41333 41334 41574 42538 42758 4360 5236 5290 5291 5293 53501 53502 53503 53506 53507 53511 53512 53583 5426 54658 5728 641488 6783 684 850886 851977 855131 855459 855595
DOID:8778	Crohn's disease	ALOX12 ALPI ATG26 Alox12 Alppl2 GPX1 ICAM1 LRRK2 Lrrk2 PHO8 PIKFYVE PLAUR PON1 PON3 PTGS2 Pon1 Pon1 Pon3 Pon3 SELL UGT1A1 Ugt1a1 Ugt1a1 Ugt301D1 Ugt302K1 Ugt303A1 Ugt304A1 Ugt316A1 Ugt35A1 Ugt35B1 Ugt35C1 Ugt35E2 Ugt36D1 Ugt36E1 Ugt36F1 Ugt37A3 Ugt37C1 Ugt37D1 Ugt37E1 Ugt49B2 ugt-61 ugt1a1 ugt1a6 ugt1a6 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7 ugt1a7	100135191 100379286 100384891 100384896 100384901 100489505 116406461 11650 11684 120892 185500 18979 200576 239 248 24861 269823 2876 312086 3383 35105 35137 35138 35139 394436 40079 406731 41333 41334 41574 42538 5329 53501 53502 53503 53506 53507 53511 53512 53583 5444 5446 54658 5743 6402 641488 66725 84024 850886 852092