GlyCosmos Portal

Mus musculus (house mouse)

Summary

Taxonomy ID: 10090
PubChem Taxonomy: 10090

Genes (662) Glycans (1270) Glycoproteins (13000) Lectins (276) Pathways (1335)

Displaying entries **301 - 325** of **1335** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Crk-like protein Cytoplasmic protein NCK2 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Proto-oncogene tyrosine-protein kinase Src RAS p21 protein activator 1 Rap guanine nucleotide exchange factor (GEF) 1 SH2/SH3 adapter protein Nck1 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and transcription activator 6 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	E9PYG6 O08908 O55033 P05480 P05622 P08556 P20033 P26450 P26618 P31240 P32883 P35235 P42225 P42227 P42230 P42232 P42337 P47941 P52633 Q03160 Q3UHC1 Q61140 Q61411 Q62077 Q62245 Q64010 Q8BTI9 Q99M51	Aprf Bcar1 Cas Crk Crkas Crkl Crko Crkol Grb4 Grb7 Hras Hras1 Kras Kras2 Mgf Mpf Nck1 Nck2 Nras Pdgfa Pdgfb Pdgfr Pdgfr1 Pdgfra Pdgfrb Pik3ca Pik3cb Pik3r1 Pik3r2 Plcg-1 Plcg1 Ptpn11 Rapgef1 Rasa1 Sis Sos1 Src Stat1 Stat3 Stat5a Stat5b Stat6
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 5 Fibroblast growth factor 6 Fibroblast growth factor 8 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Klotho Leucine-rich repeat transmembrane protein FLRT1 Leucine-rich repeat transmembrane protein FLRT2 Leucine-rich repeat transmembrane protein FLRT3	O35082 O35565 P05524 P11403 P15655 P15656 P16092 P21658 P37237 P54130 P61148 P63075 Q6RKD8 Q8BGT1 Q8BLU0 Q9EPC2 Q9ESL9 Q9ESS2	Aigf Fgf-1 Fgf-2 Fgf-3 Fgf-4 Fgf-5 Fgf-6 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf6 Fgf8 Fgf9 Fgfa Fgfr1 Flg Flrt1 Flrt2 Flrt3 Hstf2 Int-2 Kfgf Kiaa0405 Kiaa1469 Kl
Drug-mediated inhibition of CDK4/CDK6 activity	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3	P25322 P30280 P30282 P30285 Q64261	Ccnd1 Ccnd2 Ccnd3 Cdk4 Cdk6 Cdkn6 Crk2 Crk3 Cyl-1 Cyl-2 Cyl-3
Drug-mediated inhibition of ERBB2 signaling	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P07901 P70424 Q61081 Q80TH2	Cdc37 Erbb2 Erbb2ip Erbin Hsp86 Hsp86-1 Hsp90aa1 Hspca Kiaa1225 Kiaa3023 Lap2 Neu
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	P16056 Q08048	Hgf Met
Dual Incision in GG-NER	Chromodomain-helicase-DNA-binding protein 1-like Cullin-4A Cullin-4B DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair endonuclease XPF DNA repair protein complementing XP-A cells homolog E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A2A432 O08811 O35654 O54956 O70422 O88554 P07903 P0CG49 P0CG50 P11103 P17918 P35601 P35689 P49135 P52431 P62878 P62983 P62984 Q3TCH7 Q3U1J4 Q62193 Q64267 Q8K2X8 Q8R323 Q8VD76 Q8VEE4 Q99J62 Q99J79 Q9CQ36 Q9CQ71 Q9CWP8 Q9CXF7 Q9D0F6 Q9DBA9 Q9EQ28 Q9JIB4 Q9JKP7 Q9QUG2 Q9QZD4 Q9WUK4 Q9WVF7	Adprp Adprt Adprt1 Adprt2 Adprtl2 Aspartl2 Btf2p44 Chd1l Cul4a Cul4b D17Wsu155e Ddb1 Ddb2 Dinb1 Ercc-1 Ercc-5 Ercc1 Ercc2 Ercc3 Ercc4 Ercc5 Gtf2h1 Gtf2h2 Gtf2h3 Gtf2h4 Gtf2h5 Ibf-1 Kiaa0695 Parp1 Parp2 Pcna Pold1 Pold2 Pold3 Pold4 Pole Pole1 Pole2 Pole3 Pole4 Polk Rbx1 Recc1 Rfc1 Rfc2 Rfc3 Rfc4 Rfc5 Rpa1 Rpa2 Rpa3 Rpa34 Rps27a Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2 Xpa Xpac Xpb Xpbc Xpd Xpf Xpg
Dual incision in TC-NER	CDK-activating kinase assembly factor MAT1 Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA excision repair protein ERCC-6 DNA excision repair protein ERCC-8 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair endonuclease XPF DNA repair protein complementing XP-A cells homolog DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Polyubiquitin-B Polyubiquitin-C Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor SYF1 Proliferating cell nuclear antigen RNA helicase aquarius Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Transcription elongation factor A protein 1 UV-stimulated scaffold protein A Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein 830	A2A432 F8VPZ5 O08740 O08811 O35654 O54956 O70422 P07903 P08775 P0CG49 P0CG50 P10711 P17918 P35601 P35689 P49135 P51949 P52431 P60898 P61219 P62488 P62876 P62878 P62983 P62984 P97760 Q03147 Q3TCH7 Q3U1J4 Q61458 Q62193 Q63871 Q64267 Q69ZQ2 Q6A4J8 Q80UW8 Q8CFD5 Q8CFI7 Q8CFQ3 Q8K2X8 Q8R1N0 Q8R323 Q8VD76 Q8VEE4 Q923G2 Q99J62 Q99KP6 Q9CQ36 Q9CQ71 Q9CWP8 Q9D0F6 Q9D479 Q9D7M8 Q9DBA9 Q9DCD2 Q9EQ28 Q9JIB4 Q9JKP7 Q9QUG2 Q9QZD4 Q9WUK4 Q9WVF7	Aqr Btf2p44 Cak Ccdc16 Ccnh Cdk7 Cdkn7 Ckn1 Crk4 Csa Csb Cul4a Cul4b D17Wsu155e Ddb1 Dinb1 Ercc-1 Ercc-5 Ercc1 Ercc2 Ercc3 Ercc4 Ercc5 Ercc6 Ercc8 Gtf2h1 Gtf2h2 Gtf2h3 Gtf2h4 Gtf2h5 Hausp Ibf-1 Isy1 Kiaa0560 Kiaa0695 Kiaa1160 Kiaa1530 Mat1 Mnat1 Mo15 Mpk-7 Mt1a Omcg1 Pcna Pold1 Pold2 Pold3 Pold4 Pole Pole1 Pole2 Pole3 Pole4 Polk Polr2a Polr2b Polr2c Polr2d Polr2e Polr2f Polr2g Polr2h Polr2i Polr2j Polr2k Polr2l Prp19 Prpf19 Rbx1 Recc1 Rfc1 Rfc2 Rfc3 Rfc4 Rfc5 Rpa1 Rpa2 Rpa3 Rpa34 Rpii215 Rpo2-1 Rpo2-3 Rpo2-4 Rps27a Snev Syf1 Tcea1 Tceat Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2 Usp7 Uvssa Xab2 Xpa Xpac Xpb Xpbc Xpd Xpf Xpg Zfp830 Znf830
E3 ubiquitin ligases ubiquitinate target proteins	B-cell lymphoma/leukemia 10 DNA-dependent protein kinase catalytic subunit E3 ubiquitin-protein ligase BRE1A E3 ubiquitin-protein ligase BRE1B E3 ubiquitin-protein ligase RAD18 E3 ubiquitin-protein ligase RNF144A E3 ubiquitin-protein ligase RNF152 E3 ubiquitin-protein ligase RNF181 E3 ubiquitin-protein ligase SHPRH Helicase-like transcription factor Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/G Histone H2B type 1-F/J/L Histone H2B type 1-H Histone H2B type 1-K Histone H2B type 1-M Histone H2B type 1-P Histone H2B type 2-E Parafibromin Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisome assembly protein 12 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen RNA polymerase II-associated factor 1 homolog RNA polymerase-associated protein CTR9 homolog RNA polymerase-associated protein LEO1 Ras-related GTP-binding protein A Superkiller complex protein 8 Ubiquitin-conjugating enzyme E2 A Ubiquitin-conjugating enzyme E2 B Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing adapter protein with coiled-coil	B1AUE5 P0CG49 P0CG50 P10853 P10854 P17918 P52482 P55098 P61079 P61080 P61089 P62838 P62983 P62984 P63147 P68037 P70696 P97313 Q3U319 Q5DTM8 Q5XJE5 Q62018 Q64475 Q64478 Q64524 Q6PCN7 Q6ZWY9 Q7TPQ3 Q80X95 Q8BG47 Q8CGP1 Q8CGP2 Q8JZM7 Q8K2T8 Q8VC48 Q924H7 Q925F3 Q9CY62 Q9D0K1 Q9D2M8 Q9ERF3 Q9QXK2 Q9R0A0 Q9Z0H7 Q9Z255	Bcl10 Blu Bre1a Bre1b Cdc73 Ciper Clap Ctr9 Gm185 H2b-f H2b-j H2b-l H2b-n H2bc1 H2bc11 H2bc12 H2bc13 H2bc14 H2bc15 H2bc21 H2bc3 H2bc4 H2bc6 H2bc7 H2bc8 H2bc9 Hist1h2ba Hist1h2bb Hist1h2bc Hist1h2be Hist1h2bf Hist1h2bg Hist1h2bh Hist1h2bj Hist1h2bk Hist1h2bl Hist1h2bm Hist1h2bn Hist1h2bp Hist2h2be Hltf Kiaa0155 Kiaa0161 Kiaa0661 Kiaa1844 Kiaa4116 Leo1 Mms2 Paf1 Pcna Pex10 Pex12 Pex13 Pex14 Pex2 Pmp35 Prkdc Pxmp3 Rad18 Rad18sc Rad6a Rad6b Rnf144 Rnf144a Rnf152 Rnf181 Rnf20 Rnf40 Rps27a Rraga Sh2bp1 Shprh Skic8 Smarca3 Snf2l3 Th2b Uba52 Uba80 Ubb Ubc Ubc4 Ubce5 Ubce7 Ubce7ip4 Ubcep1 Ubcep2 Ubch4 Ubch5b Ubcm3 Ube2a Ube2b Ube2d1 Ube2d2 Ube2d2a Ube2d3 Ube2e1 Ube2l3 Ube2n Ube2v2 Uev2 Uip4 Wac Wdr61 Xrcc7 Zbu1
ECM proteoglycans	Aggrecan core protein Agrin Biglycan Brevican core protein Cartilage matrix protein Cartilage oligomeric matrix protein Collagen alpha-1(IX) chain Collagen alpha-2(IX) chain Collagen, type IX, alpha 3 Decorin Dentin matrix acidic phosphoprotein 1 Dentin sialophosphoprotein Hyaluronan and proteoglycan link protein 1 Integrin alpha-2 Integrin alpha-7 Integrin alpha-8 Integrin alpha-9 Integrin alpha-IIb Integrin alpha-V Integrin alpha-X Integrin beta-1 Integrin beta-3 Integrin beta-5 Integrin beta-6 Matrilin-3 Matrilin-4 Neurocan core protein Plasminogen activator inhibitor 1 SPARC Tenascin XB Tenascin-N Tenascin-R Tenascin Versican core protein Vitronectin	A0A5F8MPH8 A2ACT7 A2ARA8 A2ASQ1 B8JK39 O35701 O54890 O55188 O70309 O89029 P07214 P09055 P22777 P28653 P28654 P29788 P43406 P51942 P55066 P97399 Q05722 Q07643 Q61282 Q61361 Q61738 Q62059 Q62469 Q80YX1 Q80Z71 Q8BYI9 Q9QUM0 Q9QUP5 Q9QXH4 Q9R0G6 Q9Z0T9	Acan Agc Agc1 Agrin Agrn Bcan Bgn Cmp Col9a1 Col9a2 Col9a3 Comp Crtl1 Crtm Cspg2 Cspg3 Dcn Dmp Dmp1 Dmp3 Dspp Hapln1 Hxb Itga2 Itga2b Itga7 Itga8 Itga9 Itgav Itgax Itgb1 Itgb3 Itgb5 Itgb6 Matn1 Matn3 Matn4 Mr1 Ncan Pai1 Planh1 Serpine1 Sparc Tnc Tnn Tnr Tnw Tnxb Vcan Vtn
EGFR Transactivation by Gastrin	Epidermal growth factor receptor GTPase HRas GTPase KRas GTPase NRas Proheparin-binding EGF-like growth factor Protein kinase C alpha type Son of sevenless homolog 1 Stromelysin-1	P08556 P20444 P28862 P32883 Q01279 Q06186 Q61411 Q62245	Dtr Egfr Hbegf Hegfl Hras Hras1 Kras Kras2 Mmp3 Nras Pkca Prkca Sos1
EGFR downregulation	Amphiregulin Cell division control protein 42 homolog E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15-like 1 Epidermal growth factor receptor substrate 15 Epidermal growth factor receptor Epigen Epsin-1 Hepatocyte growth factor-regulated tyrosine kinase substrate Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein sprouty homolog 1 Protein sprouty homolog 2 Protransforming growth factor alpha Receptor-type tyrosine-protein phosphatase kappa Rho guanine nucleotide exchange factor 7 SH3 domain-containing kinase-binding protein 1 Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A2ALK8 O88811 P01132 P0CG49 P0CG50 P22682 P31955 P35822 P35831 P42567 P48030 P60766 P62983 P62984 P70297 Q01279 Q05928 Q06186 Q60902 Q61521 Q62419 Q62420 Q62421 Q80VP1 Q8R550 Q924X1 Q99LI8 Q9ES28 Q9QXV8 Q9QXV9	Areg Arhgef7 Bcn Btc Cbl Cdc42 Dtr Een1 Egf Egfr Epgn Epn1 Eps15 Eps15-rs Eps15R Eps15l1 Ereg Hbegf Hbp Hegfl Hgs Hrs Kiaa0142 Pak3bp Ptpk Ptpn12 Ptpn3 Ptprk Rps27a Ruk Sdgf Seta Sh3d2a Sh3d2b Sh3d2c Sh3d2c2 Sh3gl1 Sh3gl2 Sh3gl3 Sh3kbp1 Spry1 Spry2 Stam Stam1 Stam2 Tgfa Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	P01132 P31955 P48030 Q01279 Q05928 Q06186 Q61521 Q62077 Q924X1	Areg Bcn Btc Dtr Egf Egfr Epgn Ereg Hbegf Hegfl Plcg-1 Plcg1 Sdgf Tgfa
EGR2 and SOX10-mediated initiation of Schwann cell myelination	Adhesion G-protein coupled receptor G6	Q6F3F9	Adgrg6 Dreg Gm222 Gpr126
EML4 and NUDC in mitotic spindle formation	Aurora kinase B B9 domain-containing protein 2 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 20 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Echinoderm microtubule-associated protein-like 4 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup98-Nup96 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin SEH1 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 1 Spindle and kinetochore-associated protein 2 ZW10 interactor	A2AGT5 E9Q3P4 O08901 O35216 O35685 O54692 O70126 O88485 O88487 P28740 P46061 P49452 P59235 P62715 P63005 P63087 P63168 P63330 Q07832 Q3TJM4 Q3U3S3 Q3UA16 Q3UK10 Q3UMY5 Q5F2E8 Q60996 Q61151 Q61166 Q6P5F9 Q6PD03 Q6PD28 Q6PDL0 Q6PFD9 Q6RT24 Q6ZWU9 Q76MZ3 Q7TNL5 Q7TNP2 Q7TSY8 Q80TV8 Q8BH74 Q8BHK9 Q8BHX3 Q8BK67 Q8BRT1 Q8C0N1 Q8C3Y4 Q8C4M7 Q8CJF7 Q8K015 Q8K1K4 Q8K305 Q8R060 Q8R0G9 Q8R1Q8 Q8R2U0 Q8R480 Q91WD7 Q922J3 Q922S8 Q923A2 Q99P69 Q9CPQ5 Q9CPV1 Q9CPV5 Q9CQ82 Q9CQA0 Q9CQU5 Q9CR46 Q9CWU9 Q9CXH7 Q9CY25 Q9CYC5 Q9CZ92 Q9CZA6 Q9CZW2 Q9D083 Q9D084 Q9D0F1 Q9D0M5 Q9D1M0 Q9ERR1 Q9ERU9 Q9ESN5 Q9JHU4 Q9JJ66 Q9QYM8 Q9WTX8 Q9WU62 Q9WVA3 Q9Z0W3 Q9Z1B5 Q9Z1S0	Ahctf1 Aik2 Aim1 Airk2 Apitd1 Ark2 Aurkb B9d2 Bub1 Bub1b Bub3 Ccdc99 Cdc20 Cdca1 Cdca8 Cenpa Cenpc Cenpc1 Cenpe Cenpf Cenph Cenpi Cenpk Cenpl Cenpm Cenpn Cenpo Cenpp Cenpq Cenpr Cenps Cenpt Cenpu Ckap5 Clasp1 Clasp2 Clip1 Crm1 D10Ertd749e Dhc1 Dlc1 Dlc2 Dnch1 Dnchc1 Dnci1 Dnci2 Dncic1 Dncic2 Dncl1 Dnclc1 Dncli1 Dncli2 Dnclic1 Dnclic2 Dsn1 Dyhc Dync1h1 Dync1i1 Dync1i2 Dync1li1 Dync1li2 Dynll1 Dynll2 Elys Eml4 Enp Ercc6l FAAP16 Fam33a Fshprh1 Fug1 Gtl1-13 Hec1 Incenp Itgb3bp Kiaa0166 Kiaa0197 Kiaa0622 Kiaa0627 Kiaa1361 Kiaa1470 Kiaa4006 Kiaa4046 Kif18a Kif2 Kif2a Kif2b Kif2c Kns2 Kntc1 Kntc2 Lis-1 Lis1 MHF1 Mad1 Mad1l1 Mad2a Mad2l1 Mad3l Mapre1 Mcm21r Mis12 Mlf1ip Ndc80 Nde1 Ndel1 Nrif3 Nsl1 Nudc Nude Nudel Nuf2 Nuf2r Nup107 Nup133 Nup160 Nup37 Nup43 Nup85 Nup98 Pafah1b1 Pafaha Pane1 Pcnt1 Plk Plk1 Pmf1 Ppp1cc Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Ranbp2 Rangap1 Rcc2 Rps27 Rsn Sec13 Sec13l1 Seh1l Sgo1 Sgo2 Sgol1 Sgol2 Sgol2a Ska1 Ska2 Solt Spbc24 Spbc25 Spc24 Spc25 Spdl1 Stk1 Stk12 Stk5 Taok1 Xpo1 Zw10 Zwilch Zwint
EPH-Ephrin signaling	Ephrin type-A receptor 10 Ephrin type-A receptor 1 Ephrin type-A receptor 2 Ephrin type-A receptor 3 Ephrin type-A receptor 4 Ephrin type-A receptor 6 Ephrin type-A receptor 7 Ephrin type-A receptor 8 Ephrin type-B receptor 1 Ephrin type-B receptor 2 Ephrin type-B receptor 3 Ephrin type-B receptor 4 Ephrin type-B receptor 6 Ephrin-A1 Ephrin-A2 Ephrin-A3 Ephrin-A4 Ephrin-A5 Ephrin-B1 Ephrin-B2 Ephrin-B3	O08542 O08543 O08545 O08644 O09127 O35393 P29319 P52793 P52795 P52800 P52801 P54754 P54761 P54763 Q03137 Q03145 Q60750 Q61772 Q62413 Q8BYG9 Q8CBF3	Cekl Ebk Eck Eek Efna1 Efna2 Efna3 Efna4 Efna5 Efnb1 Efnb2 Efnb3 Ehk-2 Ehk2 Ehk3 Elf1 Elf2 Epgl1 Epha1 Epha10 Epha2 Epha3 Epha4 Epha6 Epha7 Epha8 Ephb1 Ephb2 Ephb3 Ephb4 Ephb6 Epl1 Epl2 Epl3 Epl4 Epl5 Epl6 Epl7 Eplg2 Eplg3 Eplg4 Eplg5 Eplg6 Eplg7 Epth3 Esk Etk1 Etk2 Htk Htkl Lerk1 Lerk2 Lerk3 Lerk4 Lerk5 Lerk6 Lerk7 Mdk1 Mdk2 Mdk5 Mek4 Myk1 Myk2 Nuk Sek Sek1 Sek2 Sek3 Sek4 Stra1 Tyro4
EPH-ephrin mediated repulsion of cells	72 kDa type IV collagenase Ephrin type-B receptor 1 Ephrin type-B receptor 2 Ephrin type-B receptor 3 Ephrin type-B receptor 4 Ephrin type-B receptor 6 Ephrin-B1 Ephrin-B2 Ephrin-B3 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Matrix metalloproteinase-9 Nicastrin Presenilin-1 Presenilin-2 Proto-oncogene tyrosine-protein kinase Src Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor TIAM1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O08644 O35393 P05480 P25911 P33434 P39688 P41245 P49769 P52795 P52800 P54754 P54761 P54763 P57716 P63001 Q04736 Q60610 Q60992 Q61144 Q8BVF7 Q8C7N7 Q8CBF3 Q9CQR7 Q9R0C8	Ad3h Ad4h Alg3 Aph1a Aph1b Cekl Clg4b Efnb1 Efnb2 Efnb3 Elf2 Ephb1 Ephb2 Ephb3 Ephb4 Ephb6 Epl2 Epl5 Eplg2 Eplg5 Epth3 Etk2 Fyn Htk Htkl Lerk2 Lerk5 Lyn Mdk2 Mdk5 Mmp2 Mmp9 Myk1 Ncstn Nuk Pen2 Ps-2 Psen1 Psen2 Psenen Psnl1 Psnl2 Rac1 Sek3 Sek4 Src Stra1 Tiam-1 Tiam1 Vav2 Vav3 Yes Yes1
EPHA-mediated growth cone collapse	Ephexin-1 Proto-oncogene tyrosine-protein kinase Src Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	P05480 P25911 P39688 Q04736 Q8CHT1 Q9QUI0	Arha Arha2 Fyn Lyn Ngef Rhoa Src Yes Yes1
EPHB-mediated forward signaling	Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog GTPase HRas Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Intersectin-1 Kalirin Proto-oncogene tyrosine-protein kinase Src RAS p21 protein activator 1 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor TIAM1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Serine/threonine-protein kinase PAK 1 Syndecan-2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	A2CG49 E9PYG6 O88643 P05480 P25911 P35438 P39688 P43407 P59999 P60710 P60766 P61161 P63001 P63260 P70335 P70336 P97433 Q01097 Q04736 Q60610 Q61411 Q99JY9 Q9CPW4 Q9CVB6 Q9JM76 Q9QUI0 Q9R0Q6 Q9WV32 Q9Z0R4	Actb Actg Actg1 Actr2 Actr3 Arc20 Arha Arha2 Arhgef28 Arp2 Arp3 Arpc1a Arpc1b Arpc2 Arpc3 Arpc4 Arpc5 Cdc42 Ese1 Fyn Glurz1 Grin1 Grin2b Hras Hras1 Hspg1 Itsn Itsn1 Kalrn Kiaa1998 Lyn Pak1 Paka Rac1 Rasa1 Rgnef Rhoa Rhoip2 Rip2 Rock1 Rock2 Sdc2 Sid329 Src Synd2 Tiam-1 Tiam1 Yes Yes1
ER Quality Control Compartment (ERQC)	Polyubiquitin-B Polyubiquitin-C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG49 P0CG50 P62983 P62984	Rps27a Uba52 Uba80 Ubb Ubc Ubcep1 Ubcep2
ER-Phagosome pathway	Antigen peptide transporter 1 Antigen peptide transporter 2 Beta-2-microglobulin Calreticulin Class Ib MHC antigen Qa-2 H-2 class I histocompatibility antigen, D-37 alpha chain H-2 class I histocompatibility antigen, D-P alpha chain H-2 class I histocompatibility antigen, K-B alpha chain H-2 class I histocompatibility antigen, Q10 alpha chain H-2 class I histocompatibility antigen, Q7 alpha chain H-2 class I histocompatibility antigen, TLA(B) alpha chain Histocompatibility 2, M region locus 10.1 Histocompatibility 2, M region locus 10.2 Histocompatibility 2, M region locus 10.3 Histocompatibility 2, M region locus 10.4 Histocompatibility 2, M region locus 10.5 Histocompatibility 2, M region locus 10.6 Histocompatibility 2, M region locus 11 (Fragment) Histocompatibility 2, M region locus 1 Histocompatibility 2, M region locus 2 Histocompatibility 2, M region locus 3 Histocompatibility 2, M region locus 5 Histocompatibility 2, M region locus 9 Histocompatibility 2, Q region locus 1 Histocompatibility 2, Q region locus 2 Histocompatibility 2, Q region locus 4 Histocompatibility 2, T region locus 22 Protein disulfide-isomerase A3 Synaptosomal-associated protein 23 Syntaxin-4 Tapasin Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 8 Vesicle-trafficking protein SEC22b	A7VMS3 F6U8V3 F7CXU4 O08547 O09044 O19441 O19442 O19443 O70404 P01887 P01898 P01901 P06339 P14211 P14427 P14429 P14432 P21958 P27773 P36371 P63024 P70452 P79568 Q31093 Q31615 Q4KN81 Q6W9L1 Q85ZW5 Q85ZW6 Q85ZW7 Q85ZW8 Q85ZW9 Q8HWB2 Q9R233	Abcb2 Abcb3 B2m Calr Erp Erp60 Gm11132 Grp58 H-2M3 H2-D1 H2-Gs10 H2-K H2-K1 H2-M1 H2-M10.1 H2-M10.2 H2-M10.3 H2-M10.4 H2-M10.5 H2-M10.6 H2-M11 H2-M2 H2-M3 H2-M5 H2-M9 H2-Q1 H2-Q10 H2-Q2 H2-Q4 H2-Q6 H2-Q7 H2-T22 H2-T23 H2-T3 H2-gs10 Ham-1 Ham-2 Ham1 Ham2 M10 M9 Pdia3 Sec22b Sec22l1 Snap23 Sndt Stx4 Stx4a Syb3 Tap1 Tap2 Tapa Tapbp Vamp3 Vamp8
ERBB2 Activates PTK6 Signaling	Epidermal growth factor receptor Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein-tyrosine kinase 6 Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Receptor tyrosine-protein kinase erbB-4	A0A140LHZ9 O35181 P01132 P56974 P70424 Q01279 Q05928 Q06186 Q61521 Q61526 Q61527 Q64434	Bcn Btc Dtr Egf Egfr Erbb2 Erbb3 Erbb4 Ereg Hbegf Hegfl Kiaa3023 Mer4 Neu Nrg1 Nrg2 Nrg3 Ptk6 Sik
ERBB2 Regulates Cell Motility	Epidermal growth factor receptor Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein MEMO1 Protein diaphanous homolog 1 Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Receptor tyrosine-protein kinase erbB-4 Transforming protein RhoA	A0A140LHZ9 O08808 O35181 P01132 P56974 P70424 Q01279 Q05928 Q06186 Q61521 Q61526 Q61527 Q91VH6 Q9QUI0	Arha Arha2 Bcn Btc Diap1 Diaph1 Dtr Egf Egfr Erbb2 Erbb3 Erbb4 Ereg Hbegf Hegfl Kiaa3023 Memo1 Mer4 Neu Nrg1 Nrg2 Nrg3 Rhoa
ERK/MAPK targets	Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-5 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	P18653 P18654 P47811 P62715 P63085 P63330 Q63844 Q76MZ3 Q7TNL5 Q7TNP2 Q8C050 Q9WUI1 Q9WUT3 Q9WVS8	Bmk1 Crk1 Csbp1 Csbp2 Erk1 Erk2 Erk5 Mapk Mapk1 Mapk11 Mapk14 Mapk3 Mapk7 Mapkapk1a Mapkapk1b Mapkapk1c Msk1 Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5d Prkm1 Prkm11 Prkm3 Rps6ka-rs1 Rps6ka1 Rps6ka2 Rps6ka3 Rps6ka5 Rsk1 Rsk2 Rsk3
ERKs are inactivated	Dual specificity protein phosphatase 3 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Serine/threonine-protein kinase VRK3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	P62715 P63085 P63330 Q63844 Q76MZ3 Q7TNL5 Q7TNP2 Q8BFV3 Q8K3G5 Q91Z46 Q9D7X3 Q9DBB1 Q9WVS8	Bmk1 Dusp3 Dusp4 Dusp6 Dusp7 Erk1 Erk2 Erk5 Mapk Mapk1 Mapk3 Mapk7 Mkp3 Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5d Prkm1 Prkm3 Vrk3
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP5 Prostaglandin E synthase 3 Serine/threonine-protein phosphatase 5	O08537 P07901 P11499 P19785 P30416 Q60676 Q64378 Q9R0Q7	Esr Esr1 Esr2 Estr Estra Estrb Fkbp4 Fkbp5 Fkbp51 Fkpb52 Hsp84 Hsp84-1 Hsp86 Hsp86-1 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Nr3a1 Nr3a2 Ppp5c Ptges3 Sid3177 Tebp

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