GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1151 - 1175** of **2090** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol
Nef mediated downregulation of MHC class I complex cell surface expression	AP-1 complex subunit beta-1 AP-1 complex subunit gamma-1 AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-1 complex subunit sigma-3 Beta-2-microglobulin HLA class I histocompatibility antigen, A alpha chain Phosphofurin acidic cluster sorting protein 1 Protein Nef	O43747 P04439 P04601 P56377 P61769 P61966 Q10567 Q6VY07 Q96PC3 Q9BXS5 Q9Y6Q5	ADTB1 ADTG AP19 AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 B2M BAM22 CLAPB2 CLAPG1 CLAPS1 CLTNM HLA-A HLAA KIAA1175 PACS1 nef
Negative feedback regulation of MAPK pathway	Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Serine/threonine-protein kinase B-raf	P04049 P15056 P27361 P28482 P36507 Q02750	BRAF BRAF1 ERK1 ERK2 MAP2K1 MAP2K2 MAPK1 MAPK3 MEK1 MEK2 MKK2 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1
Negative regulation of FGFR1 signaling	Anosmin-1 E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15520 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P11487 P22681 P23352 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	ADMLX ANOS1 CBL CBL2 ERK1 ERK2 FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 HST HST2 HSTF1 HSTF2 HYPF INT2 KAL KAL1 KALIG1 KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Negative regulation of FGFR2 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15520 O43320 O76093 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P11487 P21781 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Negative regulation of FGFR3 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43320 O76093 P05230 P08620 P09038 P0CG47 P0CG48 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 HST HSTF1 HYPF KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Negative regulation of FGFR4 signaling	Beta-klotho E3 ubiquitin-protein ligase CBL Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43320 O76093 O95750 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P22455 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 TKF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Negative regulation of FLT3	E3 ubiquitin-protein ligase CBL Fms-related tyrosine kinase 3 ligand Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein kinase FLT3 Receptor-type tyrosine-protein phosphatase eta SH2B adapter protein 3 Src-like-adapter 2 Src-like-adapter Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 6 Tyrosine-protein kinase ABL2 Tyrosine-protein kinase CSK Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14508 O14544 P0CG47 P0CG48 P22681 P36888 P41240 P42684 P49771 P62979 P62987 Q12913 Q13239 Q9H6Q3 Q9UQQ2	ABL2 ABLL ARG C20orf156 CBL CBL2 CD135 CIS2 CIS4 CSK DEP1 FLK2 FLT3 FLT3LG LNK PTPRJ RNF55 RPS27A SH2B3 SLA SLA2 SLAP SLAP1 SLAP2 SOCS2 SOCS4 SOCS6 SSI2 STATI2 STK1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Negative regulation of MAPK pathway	14-3-3 protein beta/alpha BRCA1-associated protein Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 16 Dual specificity protein phosphatase 1 Dual specificity protein phosphatase 2 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 5 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Dual specificity protein phosphatase 8 Dual specificity protein phosphatase 9 GTPase HRas GTPase NRas Kinase suppressor of Ras 1 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Polyubiquitin-B Polyubiquitin-C Progestin and adipoQ receptor family member 3 RAF proto-oncogene serine/threonine-protein kinase Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 5 Tyrosine-protein phosphatase non-receptor type 3 Tyrosine-protein phosphatase non-receptor type 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01111 P01112 P04049 P0CG47 P0CG48 P10398 P15056 P26045 P27361 P27448 P28482 P28562 P30086 P30153 P30154 P31946 P35236 P53041 P53778 P62714 P62979 P62987 P67775 Q05923 Q13115 Q13202 Q13362 Q14738 Q15172 Q15173 Q16537 Q16690 Q16828 Q16829 Q6TCH7 Q7Z569 Q8IVT5 Q99956 Q9BY84 Q9Y6W6	ARAF ARAF1 BRAF BRAF1 BRAP C11orf81 CL100 CTAK1 DUSP1 DUSP10 DUSP16 DUSP2 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 EMK2 ERK1 ERK2 ERK6 HRAS HRAS1 KIAA0044 KIAA1700 KSR KSR1 MAPK1 MAPK12 MAPK3 MARK3 MKP1 MKP2 MKP3 MKP4 MKP5 MKP7 NRAS PAC1 PAQR3 PBP PEBP PEBP1 PKS PKS2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP5 PPP5C PRKM1 PRKM2 PRKM3 PTPH1 PTPN10 PTPN3 PTPN7 PYST1 PYST2 RAF RAF1 RAFB1 RNF52 RPS27A SAPK3 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VH1 VH2 VH3 VH5 YWHAB
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15 Hepatocyte growth factor receptor Hepatocyte growth factor-regulated tyrosine kinase substrate Hepatocyte growth factor Leucine-rich repeats and immunoglobulin-like domains protein 1 Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein phosphatase eta SH3 domain-containing kinase-binding protein 1 Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14964 O75886 P08581 P0CG47 P0CG48 P14210 P17706 P18031 P22681 P40818 P42566 P62979 P62987 Q12913 Q92783 Q96B97 Q96JA1 Q99961 Q99962 Q99963	AF1P CBL CBL2 CIN85 CNSA1 CNSA2 CNSA3 DEP1 EPS15 HBP HGF HGS HPTA HRS KIAA0055 LIG1 LRIG1 MET PTP1B PTPN1 PTPN2 PTPRJ PTPT RNF55 RPS27A SH3D2A SH3D2B SH3D2C SH3GL1 SH3GL2 SH3GL3 SH3KBP1 STAM STAM1 STAM2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBPY USP8
Negative regulation of NMDA receptor-mediated neuronal transmission	Alpha-actinin-2 Calcium/calmodulin-dependent protein kinase type 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calcium/calmodulin-dependent protein kinase type IV Calmodulin-1 Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat-containing protein 7 Neurofilament light polypeptide Protein phosphatase 1E Protein phosphatase 1F	O15399 P07196 P0DP23 P35609 P49593 P78352 Q05586 Q12879 Q12959 Q13224 Q13554 Q13555 Q13557 Q14012 Q14957 Q15700 Q16566 Q8WY54 Q92796 Q96NW7 Q9UQM7	ACTN2 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-GR CAMK-II CAMK1 CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CAMKA CAMKB CAMKD CAMKG CAMKIV CAMKN DLG1 DLG2 DLG3 DLG4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GluN2D KIAA0015 KIAA0968 KIAA1072 KIAA1232 KIAA1365 LAP1 LRRC7 NEFL NF68 NFL NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D POPX1 POPX2 PPM1E PPM1F PSD95
Negative regulation of NOTCH4 signaling	14-3-3 protein zeta/delta 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase RBX1 Neurogenic locus notch homolog protein 4 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 RAC-alpha serine/threonine-protein kinase S-phase kinase-associated protein 1 Transforming acidic coiled-coil-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P31749 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62877 P62979 P62987 P63104 P63208 Q06323 Q13200 Q13616 Q15008 Q16401 Q92530 Q99436 Q99460 Q99466 Q9UL46 Q9UNM6 Q9Y6A5	AKT1 C7orf76 CUL1 DSS1 EMC19 ERIC1 HC2 HC3 HC8 HC9 HSPC IFI5111 INT3 KIAA0072 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NOTCH4 NU OCP2 PFAAP4 PKB POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RAC RBX1 RING10 RING12 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TACC3 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 YWHAZ Z
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	CXXC-type zinc finger protein 4 Protein Daple Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3	O14640 O14641 Q92997 Q9H2H0 Q9P219	CCDC88C CXXC4 DAPLE DVL1 DVL2 DVL3 IDAX KIAA0208 KIAA1509
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	Dickkopf-related protein 1 Dickkopf-related protein 2 Dickkopf-related protein 4 Kremen protein 1 Kremen protein 2 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Protein Wnt-3a Protein Wnt-4 Protein Wnt-5a Protein Wnt-9a Sclerostin Secreted frizzled-related protein 1 Secreted frizzled-related protein 2 Wnt inhibitory factor 1	O14904 O75197 O75581 O94907 P41221 P56704 P56705 Q8N474 Q8NCW0 Q96HF1 Q96MU8 Q9BQB4 Q9UBT3 Q9UBU2 Q9Y5W5	DKK1 DKK2 DKK4 FRP FRP1 FRP2 KREMEN KREMEN1 KREMEN2 KRM1 KRM2 LR3 LRP5 LRP6 LRP7 SARP1 SARP2 SFRP1 SFRP2 SOST WIF1 WNT14 WNT3A WNT4 WNT5A WNT9A
Negative regulation of activity of TFAP2 (AP-2) family transcription factors	BTB/POZ domain-containing protein KCTD15 BTB/POZ domain-containing protein KCTD1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor AP-2-delta Transcription factor AP-2-epsilon WW domain-containing oxidoreductase	P05549 P63165 P63279 Q6VUC0 Q719H9 Q7Z6R9 Q92481 Q92754 Q96SI1 Q9NZC7	AP2TF C18orf5 FOR KCTD1 KCTD15 SDR41C1 SMT3C SMT3H3 SUMO1 TFAP2 TFAP2A TFAP2B TFAP2BL1 TFAP2C TFAP2D TFAP2E UBC9 UBCE9 UBE2I UBL1 WOX1 WWOX
Negative regulation of the PI3K/AKT network	Acyl-coenzyme A thioesterase THEM4 PH domain leucine-rich repeat-containing protein phosphatase 1 PH domain leucine-rich repeat-containing protein phosphatase 2 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tribbles homolog 3	O60346 P31749 P31751 P60484 Q5T1C6 Q6ZVD8 Q96RU7 Q9Y243	AKT1 AKT2 AKT3 C20orf97 CTMP KIAA0606 KIAA0931 MMAC1 NIPK PHLPP PHLPP1 PHLPP2 PHLPPL PKB PKBG PLEKHE1 PTEN RAC SCOP SKIP3 TEP1 THEM4 TRB3 TRIB3
Negative regulators of RIG-I/MDA5 signaling	Antiviral innate immune response receptor RIG-I Autophagy protein 5 E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RNF125 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase RNF216 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein NLR family member X1 OTU domain-containing protein 5 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Poly(rC)-binding protein 2 Polyubiquitin-B Polyubiquitin-C Protein NLRC5 Serine/threonine-protein kinase TBK1 TNF receptor-associated factor 3 Tax1-binding protein 1 Tumor necrosis factor alpha-induced protein 3 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 K Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ATG12 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 O94817 O95786 P05161 P0CG47 P0CG48 P21580 P41226 P51668 P61077 P61086 P62837 P62979 P62987 Q13114 Q13526 Q14164 Q14258 Q14653 Q15366 Q7Z434 Q86UT6 Q86VP1 Q86WI3 Q8IUD6 Q96EQ8 Q96G74 Q96J02 Q9BYX4 Q9C037 Q9H1Y0 Q9NQC7 Q9NWF9 Q9UHD2 Q9UII4	APG12 APG12L APG5L ASP ATG12 ATG5 CAP-1 CEB1 CEBP1 CRAF1 CYLD CYLD1 DDX58 EFP G1P2 HERC5 HIP2 IFIH1 IKBKE IKKE IKKI IPS1 IRF3 ISG15 ITCH KIAA0151 KIAA0849 KIAA1271 LIG MAVS MDA5 NAK NLRC5 NLRX1 NOD27 NOD4 NOD5 NOD9 OTUD5 OTUD7C PCBP2 PIN1 PUBC1 RH116 RIGI RNF125 RNF135 RNF147 RNF216 RNF87 RPS27A SFT T6BP TAX1BP1 TBK1 TNFAIP3 TRAF3 TRAFAMN TRIAD3 TRIM25 TRIM4 UBA52 UBA7 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCE7IP1 UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBCH8 UBE1L UBE2 UBE2D1 UBE2D2 UBE2D3 UBE2K UBE2L6 UCRP VISA ZIN ZNF147
Nephrin family interactions	Actin nucleation-promoting factor WASL Alpha-actinin-1 Alpha-actinin-2 Alpha-actinin-3 Alpha-actinin-4 CD2-associated protein Cytoplasmic protein NCK2 Kin of IRRE-like protein 1 Kin of IRRE-like protein 2 Kin of IRRE-like protein 3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Nephrin Peripheral plasma membrane protein CASK Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Ras GTPase-activating-like protein IQGAP1 SH2/SH3 adapter protein NCK1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Tyrosine-protein kinase Fyn	O00401 O00459 O14936 O43639 O43707 O60500 P06241 P12814 P16333 P27986 P35609 P42336 P42338 P46940 Q01082 Q08043 Q13813 Q6UWL6 Q86UL8 Q8IZU9 Q96J84 Q9Y5K6	ACTN1 ACTN2 ACTN3 ACTN4 ACVRINP1 AIP1 CASK CD2AP FYN GRB1 GRB4 IQGAP1 KIAA0051 KIAA0705 KIAA1867 KIRREL KIRREL1 KIRREL2 KIRREL3 LIN2 MAGI2 NCK NCK1 NCK2 NEAS NEPH1 NEPH2 NEPH3 NPHN NPHS1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 SPTA2 SPTAN1 SPTB2 SPTBN1 WASL
Nephron development	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Delta-like protein 1 Hepatocyte nuclear factor 1-beta Hepatocyte nuclear factor 4-alpha Iroquois-class homeodomain protein IRX-1 Iroquois-class homeodomain protein IRX-2 LIM/homeobox protein Lhx1 POU domain, class 3, transcription factor 3 Protein Wnt-4 Protein Wnt-9b Protein jagged-1 Wilms tumor protein	O00548 O14905 P19544 P20264 P35680 P41235 P48742 P56705 P78414 P78504 Q8NES3 Q9BZI1	BRN1 DLL1 HNF1B HNF4 HNF4A IRX1 IRX2 IRXA1 IRXA2 JAG1 JAGL1 LFNG LHX1 LIM-1 LIM1 NR2A1 OTF8 POU3F3 TCF14 TCF2 WNT14B WNT15 WNT4 WNT9B WT1
Netrin mediated repulsion signals	Netrin receptor DCC Netrin receptor UNC5A Netrin receptor UNC5B Netrin receptor UNC5C Netrin receptor UNC5D Netrin-1 Proto-oncogene tyrosine-protein kinase Src Tyrosine-protein phosphatase non-receptor type 11	O95185 O95631 P12931 P43146 Q06124 Q6UXZ4 Q6ZN44 Q8IZJ1	DCC IGDCC1 KIAA1777 KIAA1976 NTN1 NTN1L P53RDL1 PTP2C PTPN11 SHPTP2 SRC SRC1 UNC5A UNC5B UNC5C UNC5D UNC5H1 UNC5H2 UNC5H3 UNC5H4
Netrin-1 signaling	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 E3 ubiquitin-protein ligase SIAH1 E3 ubiquitin-protein ligase SIAH2 Ezrin Hemojuvelin Neogenin Netrin receptor DCC Netrin receptor UNC5A Netrin receptor UNC5B Netrin-1 Netrin-4 Protein kinase C theta type Repulsive guidance molecule A Repulsive guidance molecule B Roundabout homolog 1 Slit homolog 1 protein Slit homolog 2 protein Slit homolog 3 protein Unconventional myosin-X	O43255 O75093 O75094 O94813 O95631 P15311 P43146 Q04759 Q6NW40 Q6ZN44 Q6ZVN8 Q8IUQ4 Q8IZJ1 Q92859 Q96B86 Q99490 Q9HB63 Q9HD67 Q9Y6N7	AGAP2 CENTG1 DCC DUTT1 EZR HFE2 HJV HUMSIAH IGDCC1 IGDCC2 KIAA0167 KIAA0799 KIAA0813 KIAA0814 KIAA1976 MEGF4 MEGF5 MYO10 NEO1 NGN NTN1 NTN1L NTN4 P53RDL1 PRKCQ PRKCT RGM RGMA RGMB RGMC ROBO1 SIAH1 SIAH2 SLIL1 SLIL2 SLIL3 SLIT1 SLIT2 SLIT3 UNC5A UNC5B UNC5H1 UNC5H2 VIL2
Neurexins and neuroligins	Amyloid-beta A4 precursor protein-binding family A member 1 Amyloid-beta A4 precursor protein-binding family A member 2 Amyloid-beta A4 precursor protein-binding family A member 3 Band 4.1-like protein 1 Band 4.1-like protein 2 Band 4.1-like protein 3 Band 4.1-like protein 5 Brain-enriched guanylate kinase-associated protein Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Disks large-associated protein 1 Disks large-associated protein 2 Disks large-associated protein 3 Disks large-associated protein 4 Drebrin-like protein Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Homer protein homolog 1 Homer protein homolog 2 Homer protein homolog 3 Leucine-rich repeat transmembrane neuronal protein 1 Leucine-rich repeat transmembrane neuronal protein 2 Leucine-rich repeat transmembrane neuronal protein 3 Leucine-rich repeat transmembrane neuronal protein 4 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 5 Neurexin-1-beta Neurexin-1 Neurexin-2-beta Neurexin-2 Neurexin-3-beta Neurexin-3 Neuroligin-1 Neuroligin-2 Neuroligin-3 Neuroligin-4, X-linked Neuroligin-4, Y-linked PDZ and LIM domain protein 5 Peripheral plasma membrane protein CASK Protein 4.1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C SH3 and multiple ankyrin repeat domains protein 1 SH3 and multiple ankyrin repeat domains protein 2 SH3 and multiple ankyrin repeat domains protein 3 Sharpin Signal-induced proliferation-associated 1-like protein 1 Synaptotagmin-10 Synaptotagmin-12 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-7 Synaptotagmin-9 Syntaxin-1A Syntaxin-binding protein 1	O14490 O14910 O14936 O15399 O43166 O43300 O43491 O43581 O95886 O96018 P11171 P21579 P41594 P58400 P58401 P61764 P78352 Q02410 Q05586 Q12879 Q13224 Q13255 Q14957 Q15700 Q16623 Q6XYQ8 Q86SS6 Q86UE6 Q86VH4 Q86VH5 Q86YM7 Q8IV01 Q8N0W4 Q8N2Q7 Q8N9I0 Q8NFZ3 Q8NFZ4 Q92796 Q96HC4 Q99767 Q9BUH8 Q9BYB0 Q9H0F6 Q9H4G0 Q9HAP6 Q9HCM4 Q9HDB5 Q9NSB8 Q9NSC5 Q9NUP9 Q9NZ94 Q9P1A6 Q9P2S2 Q9UJU6 Q9ULB1 Q9UPX8 Q9Y2H0 Q9Y2J2 Q9Y4C0 Q9Y566	APBA1 APBA2 APBA3 BEGAIN C14orf60 C8orf68 CASK CMAP CORTBP1 DAL1 DAP1 DAP2 DAP3 DAP4 DBNL DLG2 DLG3 DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 E41P E6TP1 ENH EPB41 EPB41L1 EPB41L2 EPB41L3 EPB41L5 ERICH1-AS1 GKAP GPRC1A GPRC1E GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRM1 GRM5 GluN2D HOMER1 HOMER2 HOMER3 KIAA0338 KIAA0416 KIAA0440 KIAA0578 KIAA0743 KIAA0921 KIAA0951 KIAA0964 KIAA0987 KIAA1022 KIAA1070 KIAA1232 KIAA1260 KIAA1366 KIAA1446 KIAA1480 KIAA1548 KIAA1650 LIN2 LIN7A LIN7B LIN7C LRRN2 LRRTM1 LRRTM2 LRRTM3 LRRTM4 MALS1 MALS2 MALS3 MGLUR1 MGLUR5 MINT1 MINT2 MINT3 NL3 NLGN1 NLGN2 NLGN3 NLGN4 NLGN4X NLGN4Y NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D NRXN1 NRXN2 NRXN3 PCANAP7 PDLIM5 PROSAP1 PROSAP2 PSAP2 PSD95 SAPAP4 SH3P7 SHANK1 SHANK2 SHANK3 SHARPIN SIPA1L1 SIPL1 STX1 STX1A STXBP1 SVP65 SYN47 SYT SYT1 SYT10 SYT12 SYT2 SYT7 SYT9 UNC18A VELI1 VELI2 VELI3 X11 X11L X11L2
Neurofascin interactions	Ankyrin-1 Contactin-1 Contactin-associated protein 1 Neurofascin Neuronal cell adhesion molecule Neuronal migration protein doublecortin Syntenin-1	O00560 O43602 O94856 P16157 P78357 Q12860 Q92823	ANK ANK1 CASPR CNTN1 CNTNAP1 DBCN DCX KIAA0343 KIAA0756 LISX MDA9 NFASC NRCAM NRXN4 SDCBP SYCL
Neurophilin interactions with VEGF and VEGFR	Neuropilin-1 Neuropilin-2 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2	O14786 O60462 P17948 P35968	FLK1 FLT FLT1 FRT KDR NRP NRP1 NRP2 VEGF165R VEGF165R2 VEGFR1 VEGFR2
Neurotransmitter clearance	Acetylcholinesterase Cholinesterase Solute carrier family 22 member 1 Solute carrier family 22 member 2	O15244 O15245 P06276 P22303	ACHE BCHE CHE1 OCT1 OCT2 SLC22A1 SLC22A2
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3D 5-hydroxytryptamine receptor 3E Glycine receptor subunit alpha-1 Glycine receptor subunit alpha-2 Glycine receptor subunit alpha-3 Glycine receptor subunit beta Neurobeachin	A5X5Y0 O75311 O95264 P23415 P23416 P46098 P48167 Q70Z44 Q8NFP9 Q8WXA8	5HT3R BCL8B GLRA1 GLRA2 GLRA3 GLRB HTR3 HTR3A HTR3B HTR3C HTR3D HTR3E KIAA1544 LYST2 NBEA

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