GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
Downregulation of ERBB2:ERBB3 signaling	E3 ubiquitin-protein ligase NRDP1 Polyubiquitin-B Polyubiquitin-C Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Receptor tyrosine-protein kinase erbB-2 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14511 P04626 P0CG47 P0CG48 P31749 P31751 P40818 P62979 P62987 Q02297 Q9H4P4 Q9Y243	AKT1 AKT2 AKT3 ERBB2 FLRF GGF HER2 HGL HRGA KIAA0055 MLN19 NDF NEU NGL NRDP1 NRG1 NRG2 NTAK PKB PKBG RAC RNF41 RPS27A SMDF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBPY USP8	Homo sapiens (human)
Evasion by RSV of host interferon responses	Antiviral innate immune response receptor RIG-I CREB-binding protein Cullin-5 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin/ISG15 ligase TRIM25 Elongin-B Elongin-C Histone acetyltransferase p300 Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha/beta receptor 1 Interferon beta Interferon regulatory factor 3 Interferon-induced helicase C domain-containing protein 1 Interferon-induced, double-stranded RNA-activated protein kinase Mitochondrial antiviral-signaling protein Non-receptor tyrosine-protein kinase TYK2 Non-structural protein 1 Non-structural protein 2 Nucleoprotein Polyubiquitin-B Polyubiquitin-C Signal transducer and activator of transcription 2 Tyrosine-protein kinase JAK1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O95786 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P03418 P04543 P05013 P05014 P05015 P0CG47 P0CG48 P0DOE9 P17181 P19525 P23458 P29597 P32881 P52630 P62877 P62979 P62987 Q09472 Q14258 Q14653 Q15369 Q15370 Q7Z434 Q92793 Q93034 Q9BYX4	1B 1C CBP CREBBP CUL5 DDX58 EFP EIF2AK2 ELOB ELOC EP300 IFB IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR IFNAR1 IFNB IFNB1 IPS1 IRF3 JAK1 JAK1A JAK1B KIAA1271 MAVS MDA5 N NS1 NS2 P300 PKR PRKR RBX1 RH116 RIGI RNF147 RNF75 ROC1 RPS27A STAT2 TCEB1 TCEB2 TRIM25 TYK2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VACM1 VISA ZNF147	Homo sapiens (human)
WNT5A-dependent internalization of FZD4	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Beta-arrestin-2 Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Frizzled-4 Protein Wnt-5a Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type Segment polarity protein dishevelled homolog DVL-2	O14641 O94973 O95782 P05129 P05771 P09496 P09497 P17252 P32121 P41221 P53680 P63010 Q00610 Q96CW1 Q9ULV1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARB2 ARR2 ARRB2 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTB CLTC CLTCL2 DVL2 FZD4 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0899 PKCA PKCB PKCG PRKACA PRKCA PRKCB PRKCB1 PRKCG WNT5A	Homo sapiens (human)
Formation of editosomes by ADAR proteins	Double-stranded RNA-specific adenosine deaminase Double-stranded RNA-specific editase 1	P55265 P78563	ADAR ADAR1 ADAR2 ADARB1 DRADA2 DSRAD G1P1 IFI4 RED1	Homo sapiens (human)
Glucagon signaling in metabolic regulation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Glucagon receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Pro-glucagon	O43306 O60262 O60266 O60503 O95622 P01275 P16520 P40145 P47871 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GCG GCGR GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT10 GNGT11 GNGT3 GNGT4 GNGT5 GNGT7 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	O14610 O14775 O60262 O75899 P16520 P48050 P48051 P48544 P48549 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P63252 P78508 Q14500 Q92806 Q99712 Q9HAV0 Q9NPI9 Q9P2W3 Q9UBI6 Q9UBS5 Q9UK08	GABBR1 GABBR2 GIRK1 GIRK2 GIRK3 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPR51 GPRC3A GPRC3B IRK1 IRK2 IRK3 KATP2 KCNJ10 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ7 KCNJ9 KCNJN1	Homo sapiens (human)
Signaling by RNF43 mutants	E3 ubiquitin-protein ligase RNF43 Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-8 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Protein Wnt-3a	O60353 O75197 O75581 P56704 Q13467 Q68DV7 Q9H461 Q9ULV1	C2orf31 FZD4 FZD5 FZD6 FZD8 LR3 LRP5 LRP6 LRP7 RNF43 WNT3A	Homo sapiens (human)
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2	Homo sapiens (human)
MPS I - Hurler syndrome	Alpha-L-iduronidase	P35475	IDUA	Homo sapiens (human)
APC truncation mutants are not K63 polyubiquitinated	Adenomatous polyposis coli protein	P25054	APC DP2.5	Homo sapiens (human)
Retrograde transport at the Trans-Golgi-Network	ADP-ribosylation factor-like protein 1 ADP-ribosylation factor-related protein 1 Alpha-soluble NSF attachment protein Arfaptin-2 Beta-soluble NSF attachment protein Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 GRIP and coiled-coil domain-containing protein 1 GRIP and coiled-coil domain-containing protein 2 Gamma-soluble NSF attachment protein Golgin subfamily A member 1 Golgin subfamily A member 4 Guanine nucleotide exchange factor subunit RIC1 N-alpha-acetyltransferase 30 N-alpha-acetyltransferase 35, NatC auxiliary subunit N-alpha-acetyltransferase 38, NatC auxiliary subunit Perilipin-3 Protein SYS1 homolog RAB6A-GEF complex partner protein 2 Rab9 effector protein with kelch motifs Ras-related protein Rab-43 Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-9A Ras-related protein Rab-9B Rho-related BTB domain-containing protein 3 Short coiled-coil protein Syntaxin-10 Syntaxin-16 Syntaxin-6 TATA element modulatory factor Trans-Golgi network integral membrane protein 2 USP6 N-terminal-like protein Vacuolar protein sorting-associated protein 51 homolog Vacuolar protein sorting-associated protein 52 homolog Vacuolar protein sorting-associated protein 53 homolog Vacuolar protein sorting-associated protein 54 Vesicle transport through interaction with t-SNAREs homolog 1A Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-fusing ATPase	O14662 O43493 O43752 O60499 O60664 O75379 O94955 P11717 P20340 P20645 P40616 P46459 P51151 P53365 P54920 P82094 P83436 Q13439 Q13795 Q14746 Q147X3 Q15836 Q4ADV7 Q5VIR6 Q5VZE5 Q7Z6M1 Q86YS6 Q8IWJ2 Q8N1B4 Q8N2H4 Q8WTW3 Q92546 Q92738 Q92805 Q96AJ9 Q96CN9 Q96JB2 Q96MW5 Q99747 Q9BRA0 Q9H115 Q9H9E3 Q9NP90 Q9NRW1 Q9P1Q0 Q9UID3 Q9UIL1 Q9UP83 Q9Y2V7	ANG2 ARA160 ARFIP2 ARFRP1 ARL1 ARP1 C11orf2 C11orf3 C14orf35 C20orf169 CIP150 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 EGAP FFR GCC1 GCC2 GOLGA1 GOLGA4 GOLTC1 GTC90 HCC8 IGF2R KIAA0019 KIAA0258 KIAA0336 KIAA0878 KIAA1134 KIAA1381 KIAA1432 LDLB LDLC LSMD1 M6PR M6PRBP1 MAK10 MAK3 MAK31 MPR46 MPRD MPRI NAA30 NAA35 NAA38 NAPA NAPB NAPG NAT12 NSF PFAAP2 PLIN3 POR1 RAB41 RAB43 RAB6 RAB6A RAB6B RAB9 RAB9A RAB9B RAB9L RAB9P40 RABEPK RANBP2L4 RGP1 RHOBTB3 RIC1 SACM2L SCOC SCOCO SEC34 SNAPA SNAPB SNAPG STX10 STX16 STX6 SYB3 SYN10 SYS1 TGN46 TGN51 TGOLN2 TIP47 TMF1 USP6NL VAMP3 VAMP4 VPS51 VPS52 VPS53 VPS54 VTI1A	Homo sapiens (human)
Defective F9 activation	Coagulation factor IX Coagulation factor XI Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V	P00740 P03951 P07359 P13224 P14770 P40197	F11 F9 GP1BA GP1BB GP5 GP9	Homo sapiens (human)
Electric Transmission Across Gap Junctions	Gap junction alpha-10 protein Gap junction delta-2 protein Gap junction gamma-1 protein Pannexin-1 Pannexin-2	P36383 Q969M2 Q96RD6 Q96RD7 Q9UKL4	CX62 GJA10 GJA7 GJA9 GJC1 GJD2 MRS1 PANX1 PANX2	Homo sapiens (human)
Disinhibition of SNARE formation	Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type Syntaxin-4 Syntaxin-binding protein 3	O00186 P05129 P05771 P17252 Q12846	PKCA PKCB PKCG PRKACA PRKCA PRKCB PRKCB1 PRKCG STX4 STX4A STXBP3	Homo sapiens (human)
KEAP1-NFE2L2 pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Breast cancer type 1 susceptibility protein Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Cullin-3 Cyclin-dependent kinase inhibitor 1 Dipeptidyl peptidase 3 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase TRIM21 Eukaryotic translation initiation factor 2-alpha kinase 3 Kelch-like ECH-associated protein 1 Microtubule-associated proteins 1A/1B light chain 3B Mitochondrial ubiquitin ligase activator of NFKB 1 Nuclear factor erythroid 2-related factor 2 Nuclear protein localization protein 4 homolog Partner and localizer of BRCA2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein X Protein kinase C delta type Protein kinase C iota type RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Sequestosome-1 Sestrin-1 Sestrin-2 Transitional endoplasmic reticulum ATPase UBX domain-containing protein 7 Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 O94888 P0CG47 P0CG48 P17980 P19474 P19784 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P31749 P31751 P35998 P38398 P38936 P41743 P43686 P48556 P49720 P49721 P51665 P55072 P58004 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P67870 P68400 Q05655 Q13200 Q13501 Q13618 Q14145 Q15008 Q16186 Q16236 Q2F514 Q5JTC6 Q86YC2 Q8TAT6 Q92890 Q969V5 Q99436 Q99460 Q9GZQ8 Q9NY33 Q9NZJ5 Q9UNM6 Q9Y243 Q9Y6P5	ADRM1 AKT1 AKT2 AKT3 AMER1 BRCA1 C1orf166 C7orf76 CAP20 CDKN1 CDKN1A CIP1 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B CUL3 DPP3 DSS1 DXS1179E EIF2AK3 FAM123B FANCN G5A GIDE GP110 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC Hi95 INRF2 KEAP1 KIAA0107 KIAA0132 KIAA0617 KIAA0794 KIAA1499 KLHL19 LMPX LMPY MAP1ALC3 MAP1LC3B MAPL MB1 MDA6 MIP224 MOV34L MSS1 MUL1 MULAN NFE2L2 NPL4 NPLOC4 NRF2 NU ORCA OSIL PA26 PALB2 PEK PERK PFAAP4 PIC1 PKB PKBG PKCD POH1 PRKCD PRKCI PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RAC RBX1 RNF218 RNF53 RNF75 RNF81 RO52 ROC1 RPS27A SDI1 SEM1 SESN1 SESN2 SEST1 SEST2 SHFDG1 SHFM1 SQSTM1 SSA1 SUG1 SUG2 TBP1 TBP7 TRAP2 TRIM21 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBXD7 UBXN7 UFD1 UFD1L VCP WAF1 WTX X Y Z x	Homo sapiens (human)
GTP hydrolysis and joining of the 60S ribosomal subunit	Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic translation initiation factor 1A, X-chromosomal Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E Eukaryotic translation initiation factor 4H Eukaryotic translation initiation factor 5 Eukaryotic translation initiation factor 5B Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00303 O15371 O15372 O60841 O75821 O75822 P05198 P05386 P05387 P05388 P06730 P08708 P08865 P15880 P18077 P18124 P18621 P20042 P22090 P23396 P23588 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P39019 P39023 P40429 P41091 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47813 P47914 P49207 P50914 P55010 P55884 P60228 P60842 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q04637 Q07020 Q13347 Q14152 Q14240 Q15056 Q6P5R6 Q71UM5 Q7L2H7 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q99613 Q9UBQ5 Q9UNX3 Q9Y262 Q9Y3U8	BBC1 CCG2 D11S2243E D6S218E DDX2A DDX2B DXS648E EC45 EIF1A EIF1AX EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3C EIF3D EIF3E EIF3EIP EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF3S1 EIF3S10 EIF3S12 EIF3S2 EIF3S3 EIF3S4 EIF3S5 EIF3S6 EIF3S6IP EIF3S7 EIF3S8 EIF3S9 EIF4A EIF4A1 EIF4A2 EIF4B EIF4C EIF4E EIF4EL1 EIF4F EIF4G EIF4G1 EIF4GI EIF4H EIF5 EIF5B FAU FTE1 HFLB5 IF2 INT6 KIAA0038 KIAA0139 KIAA0741 LAMBR LAMR1 MFTL MPS1 NEDD6 PCID1 QM RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SURF-3 SURF3 TRIP1 TXREB1 UBA52 UBA80 UBCEP1 UBCEP2 WBSCR1 WSCR1	Homo sapiens (human)
Azathioprine ADME	ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 2 GMP synthase [glutamine-hydrolyzing] Glutathione S-transferase A1 Glutathione S-transferase A2 Glutathione S-transferase Mu 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanylate kinase Hypoxanthine-guanine phosphoribosyltransferase Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleotide triphosphate diphosphatase NUDT15 Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3 Thiopurine S-methyltransferase Xanthine dehydrogenase/oxidase	O15439 O15440 O43868 P00492 P08263 P09210 P09488 P12268 P15498 P15531 P20839 P22392 P47989 P49915 P51580 P52735 P63000 Q14542 Q16774 Q99808 Q9HAS3 Q9NV35 Q9UKW4	ABCC4 ABCC5 CNT2 CNT3 DER12 ENT1 ENT2 GMK GMPK GMPS GST1 GST2 GSTA1 GSTA2 GSTM1 GUK1 HNP36 HPRT HPRT1 IMPD1 IMPD2 IMPDH1 IMPDH2 MOATB MRP4 MRP5 MTH2 NDPKA NM23 NM23B NME1 NME2 NUDT15 RAC1 SLC28A2 SLC28A3 SLC29A1 SLC29A2 TC25 TPMT VAV VAV1 VAV2 VAV3 XDH XDHA	Homo sapiens (human)
Pexophagy	Endothelial PAS domain-containing protein 1 Microtubule-associated proteins 1A/1B light chain 3B Next to BRCA1 gene 1 protein Peroxisomal targeting signal 1 receptor Polyubiquitin-B Polyubiquitin-C Sequestosome-1 Serine-protein kinase ATM Ubiquitin carboxyl-terminal hydrolase 30 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P50542 P62979 P62987 Q13315 Q13501 Q14596 Q70CQ3 Q99814 Q9GZQ8	1A13B ATM BHLHE73 EPAS1 HIF2A KIAA0049 M17S2 MAP1ALC3 MAP1LC3B MOP2 NBR1 ORCA OSIL PASD2 PEX5 PXR1 RPS27A SQSTM1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP30	Homo sapiens (human)
Aberrant regulation of mitotic exit in cancer due to RB1 defects	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Retinoblastoma-associated protein S-phase kinase-associated protein 2 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06400 P30260 P51668 P51965 P60006 Q13042 Q13309 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E E2EPF FBXL1 FYR FZR FZR1 KIAA1242 KIAA1406 RB1 SFT SKP2 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	Helicase MOV-10 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 CAGH26 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MOV10 TNRC6 TNRC6A TNRC6B TNRC6C	Homo sapiens (human)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43320 O43559 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P21781 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
Tandem pore domain halothane-inhibited K+ channel (THIK)	Potassium channel subfamily K member 13	Q9HB14	KCNK13	Homo sapiens (human)
Activation of BID and translocation to mitochondria	BH3-interacting domain death agonist Caspase-8 Glycylpeptide N-tetradecanoyltransferase 1 Granzyme B	P10144 P30419 P55957 Q14790	BID CASP8 CGL1 CSPB CTLA1 GRB GZMB MCH5 NMT NMT1	Homo sapiens (human)
Formation of the ternary complex, and subsequently, the 43S complex	Eukaryotic translation initiation factor 1A, X-chromosomal Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Ribosomal protein eS27-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00303 O15371 O15372 O75821 O75822 P05198 P08708 P08865 P15880 P20042 P22090 P23396 P25398 P39019 P41091 P42677 P46781 P46782 P46783 P47813 P55884 P60228 P60866 P61247 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62701 P62753 P62841 P62847 P62851 P62854 P62857 P62861 P62979 P63220 Q13347 Q14152 Q71UM5 Q7L2H7 Q8TD47 Q99613 Q9UBQ5 Q9Y262	CCG2 D6S218E EIF1A EIF1AX EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3C EIF3D EIF3E EIF3EIP EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF3S1 EIF3S10 EIF3S12 EIF3S2 EIF3S3 EIF3S4 EIF3S5 EIF3S6 EIF3S6IP EIF3S7 EIF3S8 EIF3S9 EIF4C FAU FTE1 HFLB5 INT6 KIAA0139 LAMBR LAMR1 MFTL MPS1 PCID1 RIG RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA SCAR TRIP1 UBA80 UBCEP1	Homo sapiens (human)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi-associated PDZ and coiled-coil motif-containing protein Rho-related GTP-binding protein RhoQ	P13569 P17081 Q9HD26	ABCC7 ARHQ CAL CFTR FIG GOPC RASL7A RHOQ TC10	Homo sapiens (human)

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