GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **776 - 800** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
Scavenging by Class H Receptors	Apolipoprotein B-100 SPARC Stabilin-1 Stabilin-2	P04114 P09486 Q8WWQ8 Q9NY15	APOB FEEL1 FEEL2 FELL FEX2 HARE KIAA0246 ON SPARC STAB1 STAB2	Homo sapiens (human)
Mitochondrial translation termination	Alpha-ketoglutarate dehydrogenase component 4 GTPase Era, mitochondrial Large ribosomal subunit protein bL12m Large ribosomal subunit protein bL17m Large ribosomal subunit protein bL19m Large ribosomal subunit protein bL20m Large ribosomal subunit protein bL21m Large ribosomal subunit protein bL27m Large ribosomal subunit protein bL28m Large ribosomal subunit protein bL32m Large ribosomal subunit protein bL33m Large ribosomal subunit protein bL34m Large ribosomal subunit protein bL35m Large ribosomal subunit protein bL36m Large ribosomal subunit protein bL9m Large ribosomal subunit protein mL37 Large ribosomal subunit protein mL38 Large ribosomal subunit protein mL39 Large ribosomal subunit protein mL40 Large ribosomal subunit protein mL41 Large ribosomal subunit protein mL42 Large ribosomal subunit protein mL43 Large ribosomal subunit protein mL44 Large ribosomal subunit protein mL45 Large ribosomal subunit protein mL46 Large ribosomal subunit protein mL48 Large ribosomal subunit protein mL49 Large ribosomal subunit protein mL50 Large ribosomal subunit protein mL51 Large ribosomal subunit protein mL52 Large ribosomal subunit protein mL53 Large ribosomal subunit protein mL54 Large ribosomal subunit protein mL55 Large ribosomal subunit protein mL62 Large ribosomal subunit protein mL63 Large ribosomal subunit protein mL64 Large ribosomal subunit protein mL65 Large ribosomal subunit protein mL66 Large ribosomal subunit protein uL10m Large ribosomal subunit protein uL11m Large ribosomal subunit protein uL13m Large ribosomal subunit protein uL14m Large ribosomal subunit protein uL15m Large ribosomal subunit protein uL16m Large ribosomal subunit protein uL18m Large ribosomal subunit protein uL1m Large ribosomal subunit protein uL22m Large ribosomal subunit protein uL23m Large ribosomal subunit protein uL24m Large ribosomal subunit protein uL29m Large ribosomal subunit protein uL2m Large ribosomal subunit protein uL30m Large ribosomal subunit protein uL3m Large ribosomal subunit protein uL4m Mitochondrial inner membrane protein OXA1L Peptide chain release factor 1-like, mitochondrial Ribosome-recycling factor, mitochondrial Ribosome-releasing factor 2, mitochondrial Small ribosomal subunit protein bS16m Small ribosomal subunit protein bS18m Small ribosomal subunit protein bS1m Small ribosomal subunit protein bS21m Small ribosomal subunit protein bS6m Small ribosomal subunit protein mS22 Small ribosomal subunit protein mS23 Small ribosomal subunit protein mS25 Small ribosomal subunit protein mS26 Small ribosomal subunit protein mS27 Small ribosomal subunit protein mS29 Small ribosomal subunit protein mS31 Small ribosomal subunit protein mS33 Small ribosomal subunit protein mS34 Small ribosomal subunit protein mS35 Small ribosomal subunit protein mS37 Small ribosomal subunit protein mS38 Small ribosomal subunit protein mS39 Small ribosomal subunit protein mS40 Small ribosomal subunit protein uS10m Small ribosomal subunit protein uS11m Small ribosomal subunit protein uS12m Small ribosomal subunit protein uS14m Small ribosomal subunit protein uS15m Small ribosomal subunit protein uS17m Small ribosomal subunit protein uS2m Small ribosomal subunit protein uS3m Small ribosomal subunit protein uS5m Small ribosomal subunit protein uS7m Small ribosomal subunit protein uS9m	O15235 O60783 O75394 O75616 P09001 P49406 P51398 P52815 P82650 P82663 P82664 P82673 P82675 P82909 P82912 P82914 P82921 P82930 P82932 P82933 Q13084 Q13405 Q14197 Q15070 Q16540 Q4U2R6 Q5T653 Q6P161 Q6P1L8 Q7Z2W9 Q7Z7F7 Q7Z7H8 Q86TS9 Q8IXM3 Q8N5N7 Q8N983 Q8TAE8 Q8TCC3 Q92552 Q92665 Q969S9 Q96A35 Q96BP2 Q96DV4 Q96E11 Q96EL2 Q96EL3 Q96EY7 Q96GC5 Q9BQ48 Q9BQC6 Q9BRJ2 Q9BYC8 Q9BYC9 Q9BYD1 Q9BYD2 Q9BYD3 Q9BYD6 Q9BYN8 Q9BZE1 Q9H0U6 Q9H2W6 Q9H9J2 Q9HD33 Q9NP92 Q9NQ50 Q9NRX2 Q9NVS2 Q9NWT8 Q9NWU5 Q9NX20 Q9NYK5 Q9NZE8 Q9P015 Q9P0J6 Q9P0M9 Q9UGC7 Q9Y291 Q9Y2Q9 Q9Y2R5 Q9Y2R9 Q9Y399 Q9Y3B7 Q9Y3D3 Q9Y3D5 Q9Y3D9 Q9Y676 Q9Y6G3	AIP AKIP AURKAIP1 BMRP BRIP1 C10orf34 C11orf4 C15orf4 C20orf193 C21orf101 C21orf92 C2orf1 C3orf5 C6orf14 CHCHD1 DAP3 DS1 EFG2 ERAL1 GADD45GIP1 GFM2 HERA ICT1 IMOGN38 KGD4 KIAA0104 KIAA0264 L23MRP LIECG2 LIP2 MAAT1 MRL3 MRP63 MRP64 MRPL1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL19 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL30 MRPL31 MRPL32 MRPL33 MRPL34 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL41 MRPL42 MRPL43 MRPL44 MRPL45 MRPL46 MRPL47 MRPL48 MRPL49 MRPL5 MRPL50 MRPL51 MRPL52 MRPL53 MRPL54 MRPL55 MRPL57 MRPL58 MRPL59 MRPL7 MRPL8 MRPL9 MRPS10 MRPS11 MRPS12 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS18C MRPS2 MRPS21 MRPS22 MRPS23 MRPS24 MRPS25 MRPS26 MRPS27 MRPS28 MRPS29 MRPS30 MRPS31 MRPS32 MRPS33 MRPS34 MRPS35 MRPS36 MRPS37 MRPS38 MRPS39 MRPS5 MRPS6 MRPS7 MRPS9 MRRF MTRF1A MTRF1L NCM1 NLVCF NOF1 OXA1L PDCD9 PLINP1 PRG6 PTCD3 RPL23L RPML12 RPML2 RPML25 RPML27 RPML28 RPML3 RPML31 RPML32 RPML5 RPML8 RPMS11 RPMS12 RPMS13 RPMS15 RPMS16 RPMS17 RPMS21 RPMS22 RPMS25 RPMS6 RPMS9 RPSM12 URIM	Homo sapiens (human)
G beta:gamma signalling through BTK	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Tyrosine-protein kinase BTK	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q06187 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	AGMX1 ATK BPK BTK GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9	Homo sapiens (human)
Signaling by juxtamembrane domain KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Ribavirin ADME	Adenosine deaminase Adenosine kinase Cytosolic purine 5'-nucleotidase Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 3 Inosine triphosphate pyrophosphatase Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Purine nucleoside phosphorylase Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3	O43868 P00491 P00813 P15531 P22392 P49902 P55263 Q99808 Q9BY32 Q9BZD2 Q9HAS3	ADA ADA1 ADK C20orf37 CNT2 CNT3 ENT1 ENT3 ITPA NDPKA NM23 NM23B NME1 NME2 NP NT5B NT5C2 NT5CP PNP PNT5 SLC28A2 SLC28A3 SLC29A1 SLC29A3	Homo sapiens (human)
Ubiquitin-dependent degradation of Cyclin D	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cyclin-dependent kinase 4 G1/S-specific cyclin-D1 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 P0CG47 P0CG48 P11802 P17980 P20618 P24385 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P49841 P51665 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q13200 Q15008 Q16186 Q99436 Q99460 Q9UNM6	ADRM1 BCL1 C7orf76 CCND1 CDK4 DSS1 GP110 GSK3B HC2 HC3 HC8 HC9 HSPC KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PRAD1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	Homeobox protein NANOG POU domain, class 5, transcription factor 1 Transcription factor SOX-2	P48431 Q01860 Q9H9S0	NANOG OCT3 OCT4 OTF3 POU5F1 SOX2	Homo sapiens (human)
MHC class II antigen presentation	ADP-ribosylation factor 1 AP-1 complex subunit beta-1 AP-1 complex subunit gamma-1 AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-1 complex subunit sigma-3 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Actin-related protein 10 Alpha-centractin Beta-centractin Calnexin Cathepsin B Cathepsin D Cathepsin E Cathepsin F Cathepsin K Cathepsin L2 Cathepsin O Cathepsin S Centromere-associated protein E Chromosome-associated kinesin KIF4A Chromosome-associated kinesin KIF4B Clathrin heavy chain 1 Clathrin light chain A Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dipeptidyl peptidase 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynamin-1 Dynamin-2 Dynamin-3 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Endophilin-A1 F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Gamma-interferon-inducible lysosomal thiol reductase HLA class II histocompatibility antigen gamma chain HLA class II histocompatibility antigen, DM alpha chain HLA class II histocompatibility antigen, DM beta chain HLA class II histocompatibility antigen, DO alpha chain HLA class II histocompatibility antigen, DO beta chain HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 2 Kinesin light chain 3 Kinesin light chain 4 Kinesin-1 heavy chain Kinesin-associated protein 3 Kinesin-like protein (Fragment) Kinesin-like protein (Fragment) Kinesin-like protein KIF11 Kinesin-like protein KIF15 Kinesin-like protein KIF18A Kinesin-like protein KIF20A Kinesin-like protein KIF22 Kinesin-like protein KIF23 Kinesin-like protein KIF26A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinesin-like protein KIF3A Kinesin-like protein KIF3B Kinesin-like protein KIF3C Legumain Lymphocyte activation gene 3 protein Lysosomal protective protein Oxysterol-binding protein-related protein 1 Pro-cathepsin H Procathepsin L Protein SEC13 homolog Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Protein transport protein Sec31A Rab-interacting lysosomal protein Rac GTPase-activating protein 1 Ras-related protein Rab-7a Small COPII coat GTPase SAR1B Spectrin beta chain, non-erythrocytic 2	O00139 O00399 O14576 O14782 O15020 O15066 O43237 O43747 O60911 O75935 O94855 O94973 O94979 O95235 O95239 O95486 O95487 O95782 P01903 P01906 P01909 P01911 P01920 P04233 P04440 P05538 P06340 P07339 P07711 P07858 P09496 P09668 P10619 P13284 P13762 P13765 P14091 P18627 P20036 P25774 P27824 P28067 P28068 P33176 P42025 P43234 P43235 P47755 P47756 P50570 P51149 P52732 P52907 P53634 P53680 P53992 P55735 P56377 P61163 P61966 P63010 P63167 P79483 P84077 Q00610 Q02224 Q02241 Q05193 Q07866 Q10567 Q12840 Q13409 Q13561 Q14203 Q14204 Q14807 Q15436 Q2VIQ3 Q30154 Q66K46 Q6P597 Q6PKD1 Q8N4N8 Q8NI77 Q92845 Q96CW1 Q96FJ2 Q96KX2 Q96NA2 Q96PC3 Q99538 Q99661 Q99962 Q9BTE1 Q9BXS5 Q9BXW6 Q9H0B6 Q9H0H5 Q9NS87 Q9NSK0 Q9NZ32 Q9UBX1 Q9UJW0 Q9ULI4 Q9UQ16 Q9Y496 Q9Y6B6 Q9Y6G9 Q9Y6Q5	ACTR10 ACTR11 ACTR1A ACTR1B ADTAA ADTAB ADTB1 ADTB2 ADTG AP17 AP19 AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 ARP10 ARP11 BAM22 CANX CAPAA3 CAPZA1 CAPZA2 CAPZA3 CAPZB CATL2 CD74 CENPE CLAPA1 CLAPA2 CLAPB1 CLAPB2 CLAPG1 CLAPM1 CLAPS1 CLAPS2 CLH17 CLTA CLTC CLTCL2 CLTNM CNSA2 CPPI CPSB CPSD CTRN1 CTRN2 CTSA CTSB CTSC CTSD CTSE CTSF CTSH CTSK CTSL CTSL1 CTSL2 CTSO CTSO1 CTSO2 CTSS CTSU CTSV D3S1231E DCTN1 DCTN2 DCTN22 DCTN3 DCTN4 DCTN5 DCTN50 DCTN6 DHC1 DHLAG DLC1 DLC2 DMA DMB DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DNM DNM1 DNM2 DNM3 DYHC DYN2 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 EG5 FDC GILT GSG3 HDLC1 HIP9 HLA-DMA HLA-DMB HLA-DNA HLA-DOA HLA-DOB HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLA-DZA HLASB HYPJ IFI30 IP30 KIAA0034 KIAA0079 KIAA0109 KIAA0302 KIAA0325 KIAA0359 KIAA0755 KIAA0820 KIAA0899 KIAA0905 KIAA1236 KIAA1478 KID KIF11 KIF15 KIF18A KIF2 KIF20A KIF22 KIF23 KIF26A KIF2A KIF2B KIF2C KIF3 KIF3A KIF3AP KIF3B KIF3C KIF4 KIF4A KIF4B KIF5A KIF5B KIF5C KIFAP3 KLC KLC1 KLC2 KLC2L KLC3 KLC4 KLP2 KNS KNS1 KNS2 KNSL1 KNSL4 KNSL5 KNSL6 KNSL7 KNSL8 LAG3 LGMN LIC2 MGCRACGAP MKLP1 MKLP2 NKHC1 ORP1 OSBP8 OSBPL1 OSBPL1A OSBPL1B PPGB PRSC1 RAB6KIFL RAB7 RAB7A RACGAP1 RILP RING6 RING7 SAR1B SARA2 SARB SCA5 SEC13 SEC13A SEC13L1 SEC13R SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A SEC31L1 SH3D2A SH3GL2 SMAP SPTBN2 TRIP5 WS3	Homo sapiens (human)
Loss-of-function mutations in DBT cause MSUD2	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial	P09622 P11182 P12694 P21953	BCATE2 BCKDHA BCKDHB BCKDHE2 DBT DLD GCSL LAD PHE3	Homo sapiens (human)
Inhibition of Host mRNA Processing and RNA Silencing	Cleavage and polyadenylation specificity factor subunit 4 Non-structural protein 1 Polyadenylate-binding protein 2	O95639 P03496 Q86U42	CPSF30 CPSF4 NAR NEB1 NS PAB2 PABP2 PABPN1	Homo sapiens (human)
Complex III assembly	Complex III assembly factor LYRM7 Cytochrome b-c1 complex subunit 1, mitochondrial Cytochrome b-c1 complex subunit 10 Cytochrome b-c1 complex subunit 2, mitochondrial Cytochrome b-c1 complex subunit 6, mitochondrial Cytochrome b-c1 complex subunit 7 Cytochrome b-c1 complex subunit 8 Cytochrome b-c1 complex subunit 9 Cytochrome b-c1 complex subunit Rieske, mitochondrial Cytochrome b Cytochrome c1, heme protein, mitochondrial Frataxin, mitochondrial Iron-sulfur cluster co-chaperone protein HscB LYR motif-containing protein 4 Mitochondrial chaperone BCS1 Mitochondrial proton/calcium exchanger protein Stress-70 protein, mitochondrial Tetratricopeptide repeat protein 19, mitochondrial Ubiquinol-cytochrome c reductase complex assembly factor 1 Ubiquinol-cytochrome c reductase complex assembly factor 2 Ubiquinol-cytochrome c reductase complex assembly factor 5 Ubiquinol-cytochrome c reductase complex assembly factor 6 Ubiquinol-cytochrome-c reductase complex assembly factor 3	O14949 O14957 O95202 P00156 P07919 P08574 P14927 P22695 P31930 P38646 P47985 Q16595 Q5U5X0 Q69YU5 Q6DKK2 Q6UW78 Q8IWL3 Q8WVI0 Q9BRT2 Q9HD34 Q9NVA1 Q9UDW1 Q9Y276	BCS1 BCS1L BR BRAWNIN BZFB C11orf83 C12orf73 C20orf44 C3orf78 C5orf31 C6orf125 C6orf149 COB CYC1 CYTB DNAJC20 FRDA FXN GRP75 HSC20 HSCB HSPA9 HSPA9B ISD11 LETM1 LYRM4 LYRM7 MNF1 MT-CYB MTCYB MZM1L SMIM4 TTC19 UCRC UQBP UQCC UQCC1 UQCC2 UQCC3 UQCC5 UQCC6 UQCR UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRQ X25 mt-HSP70	Homo sapiens (human)
CaMK IV-mediated phosphorylation of CREB	Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calcium/calmodulin-dependent protein kinase type IV Calmodulin-1 Importin subunit alpha-1	P0DP23 P52292 Q13554 Q13555 Q13557 Q16566 Q8N5S9 Q96RR4 Q9UQM7	CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-GR CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CAMKA CAMKB CAMKD CAMKG CAMKIV CAMKK1 CAMKK2 CAMKKA CAMKKB KIAA0787 KIAA0968 KPNA2 RCH1 SRP1	Homo sapiens (human)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Gastric inhibitory polypeptide Glucose-dependent insulinotropic receptor Insulin gene enhancer protein ISL-1 Neuroendocrine convertase 1 Paired box protein Pax-6 Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Transcription factor GATA-4	O14842 P09681 P26367 P27487 P29120 P43694 P61009 P61371 P67812 Q15005 Q8TDV5 Q9BY50 Q9Y6A9	ADCP2 AN2 CD26 DPP4 FFAR1 GATA4 GIP GPR119 GPR40 ISL1 KIAA0102 NEC1 PAX6 PCSK1 SEC11A SEC11C SEC11L1 SEC11L3 SPC12 SPC18 SPC21 SPC22 SPC25 SPCS1 SPCS2 SPCS3 SPCS4A SPCS4C	Homo sapiens (human)
TICAM1-dependent activation of IRF3/IRF7	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon regulatory factor 7 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15455 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q14653 Q8IUC6 Q92844 Q92985 Q96CV9 Q9UHD2	CAP-1 CRAF1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI IRF3 IRF7 ITRAF KIAA0151 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TLR3 TRAF2 TRAF3 TRAFAMN TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
ATF6B (ATF6-beta) activates chaperones	Cyclic AMP-dependent transcription factor ATF-6 beta Endoplasmic reticulum chaperone BiP Membrane-bound transcription factor site-1 protease Membrane-bound transcription factor site-2 protease	O43462 P11021 Q14703 Q99941	ATF6B CREBL1 G13 GRP78 HSPA5 KIAA0091 MBTPS1 MBTPS2 S1P S2P SKI1	Homo sapiens (human)
RHOT1 GTPase cycle	Mitochondrial Rho GTPase 1 Rap1 GTPase-GDP dissociation stimulator 1 Trafficking kinesin-binding protein 1 Trafficking kinesin-binding protein 2 Unconventional myosin-XIX	O60296 P52306 Q8IXI2 Q96H55 Q9UPV9	ALS2CR3 ARHT1 KIAA0549 KIAA1042 MYO19 MYOHD1 OIP106 RAP1GDS1 RHOT1 SMGGDS TRAK1 TRAK2	Homo sapiens (human)
Defective ABCC2 causes DJS	ATP-binding cassette sub-family C member 2	Q92887	ABCC2 CMOAT CMOAT1 CMRP MRP2	Homo sapiens (human)
NOTCH3 Activation and Transmission of Signal to the Nucleus	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Epidermal growth factor receptor Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 NEDD4-like E3 ubiquitin-protein ligase WWP2 Neurogenic locus notch homolog protein 3 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Pro-epidermal growth factor Protein jagged-1 Protein jagged-2 Transforming acidic coiled-coil-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00308 O00548 O14672 O76050 P00533 P01133 P0CG47 P0CG48 P49768 P49810 P62979 P62987 P78504 Q86YT6 Q8WW43 Q92542 Q96AX9 Q96BI3 Q9NR61 Q9NZ42 Q9UM47 Q9Y219 Q9Y6A5	AD3 AD4 ADAM10 APH1A APH1B DIP1 DLL1 DLL4 EGF EGFR ERBB ERBB1 ERIC1 HER1 JAG1 JAG2 JAGL1 KIAA0253 KIAA1323 KUZ MADM MIB1 MIB2 NCSTN NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH3 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF67 RPS27A SKD STM2 TACC3 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWP2 ZZANK1 ZZANK2	Homo sapiens (human)
TWIK-releated acid-sensitive K+ channel (TASK)	Potassium channel subfamily K member 3 Potassium channel subfamily K member 9	O14649 Q9NPC2	KCNK3 KCNK9 TASK TASK1 TASK3	Homo sapiens (human)
Translesion synthesis by POLK	DNA polymerase kappa DNA polymerase zeta catalytic subunit DNA repair protein REV1 Mitotic spindle assembly checkpoint protein MAD2B Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60673 P0CG47 P0CG48 P12004 P15927 P27694 P35244 P35249 P35250 P35251 P40937 P40938 P62979 P62987 Q9UBT6 Q9UBZ9 Q9UI95	DINB1 MAD2B MAD2L2 PCNA POLK POLZ REPA1 REPA2 REPA3 REV1 REV1L REV3 REV3L REV7 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Maturation of protein 3a	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ORF3a protein Polypeptide N-acetylgalactosaminyltransferase 1	P15907 P59632 Q10472 Q11201 Q11203 Q11206 Q16842 Q8NDV1 Q9H4F1 Q9UJ37	3a CGS23 GALNT1 NANTA3 SIAT1 SIAT3C SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SIAT7B SIAT7C SIAT7D SIATL1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST6GAL1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 STHM STZ	Homo sapiens (human)
NOTCH4 Activation and Transmission of Signal to the Nucleus	14-3-3 protein zeta/delta Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 4 Nicastrin Presenilin-1 Presenilin-2 Protein jagged-1	O14672 P49768 P49810 P63104 P78504 Q8WW43 Q92542 Q96BI3 Q99466 Q9NR61 Q9NZ42	AD3 AD4 ADAM10 APH1A APH1B DLL4 INT3 JAG1 JAGL1 KIAA0253 KUZ MADM NCSTN NOTCH4 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 STM2 YWHAZ	Homo sapiens (human)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2-associated-binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O00329 O60674 P01588 P07948 P19235 P27986 P42336 P42338 P48736 Q13480 Q8WYR1 Q9Y4H2	EPO EPOR GAB1 GRB1 IRS2 JAK2 JTK8 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R5	Homo sapiens (human)
Acyl chain remodelling of PI	Cytosolic phospholipase A2 delta Cytosolic phospholipase A2 epsilon Cytosolic phospholipase A2 gamma Cytosolic phospholipase A2 zeta Cytosolic phospholipase A2 Group 10 secretory phospholipase A2 Group IID secretory phospholipase A2 Group IIE secretory phospholipase A2 Group IIF secretory phospholipase A2 Group XIIA secretory phospholipase A2 Lysophospholipid acyltransferase 7 Phospholipase A and acyltransferase 3 Phospholipase A2 group V Phospholipase A2, membrane associated Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor	O15496 P04054 P14555 P39877 P47712 P53816 Q13018 Q3MJ16 Q68DD2 Q6P4A8 Q86XP0 Q96N66 Q9BZM1 Q9BZM2 Q9NZK7 Q9UNK4 Q9UP65	BB1 CLEC13C CPLA2 HRASLS3 HREV107 LENG4 MBOAT7 OACT7 PLA2 PLA2A PLA2B PLA2G10 PLA2G12 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G4 PLA2G4A PLA2G4C PLA2G4D PLA2G4E PLA2G4F PLA2G5 PLA2L PLA2R1 PLAAT3 PLBD1 PPLA2 RASF-A SPLASH	Homo sapiens (human)
Regorafenib-resistant PDGFR mutants	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA	Homo sapiens (human)

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