GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1601 - 1625** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
KEAP1-NFE2L2 pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 APC membrane recruitment protein 1 Breast cancer type 1 susceptibility protein Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Cullin-3 Cyclin-dependent kinase inhibitor 1 Dipeptidyl peptidase 3 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase TRIM21 Eukaryotic translation initiation factor 2-alpha kinase 3 Kelch-like ECH-associated protein 1 Microtubule-associated proteins 1A/1B light chain 3B Mitochondrial ubiquitin ligase activator of NFKB 1 Nuclear factor erythroid 2-related factor 2 Nuclear protein localization protein 4 homolog Partner and localizer of BRCA2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein X Protein kinase C delta type Protein kinase C iota type RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Sequestosome-1 Sestrin-1 Sestrin-2 Transitional endoplasmic reticulum ATPase UBX domain-containing protein 7 Ubiquitin recognition factor in ER-associated degradation protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 O94888 P0CG47 P0CG48 P17980 P19474 P19784 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P31749 P31751 P35998 P38398 P38936 P41743 P43686 P48556 P49720 P49721 P51665 P55072 P58004 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P67870 P68400 Q05655 Q13200 Q13501 Q13618 Q14145 Q15008 Q16186 Q16236 Q2F514 Q5JTC6 Q86YC2 Q8TAT6 Q92890 Q969V5 Q99436 Q99460 Q9GZQ8 Q9NY33 Q9NZJ5 Q9UNM6 Q9Y243 Q9Y6P5	ADRM1 AKT1 AKT2 AKT3 AMER1 BRCA1 C1orf166 C7orf76 CAP20 CDKN1 CDKN1A CIP1 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B CUL3 DPP3 DSS1 DXS1179E EIF2AK3 FAM123B FANCN G5A GIDE GP110 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC Hi95 INRF2 KEAP1 KIAA0107 KIAA0132 KIAA0617 KIAA0794 KIAA1499 KLHL19 LMPX LMPY MAP1ALC3 MAP1LC3B MAPL MB1 MDA6 MIP224 MOV34L MSS1 MUL1 MULAN NFE2L2 NPL4 NPLOC4 NRF2 NU ORCA OSIL PA26 PALB2 PEK PERK PFAAP4 PIC1 PKB PKBG PKCD POH1 PRKCD PRKCI PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RAC RBX1 RNF218 RNF53 RNF75 RNF81 RO52 ROC1 RPS27A SDI1 SEM1 SESN1 SESN2 SEST1 SEST2 SHFDG1 SHFM1 SQSTM1 SSA1 SUG1 SUG2 TBP1 TBP7 TRAP2 TRIM21 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBXD7 UBXN7 UFD1 UFD1L VCP WAF1 WTX X Y Z x	Homo sapiens (human)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-2 E3 ubiquitin-protein ligase RBX1 Egl nine homolog 1 Elongin-B Elongin-C Endothelial PAS domain-containing protein 1 Hypoxia-inducible factor 1-alpha Hypoxia-inducible factor 3-alpha LIM domain-containing protein 1 LIM domain-containing protein ajuba Polyubiquitin-B Polyubiquitin-C Prolyl hydroxylase EGLN2 Prolyl hydroxylase EGLN3 Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Wilms tumor protein 1-interacting protein von Hippel-Lindau disease tumor suppressor	A6NIX2 O00231 O00232 O00487 O14818 O43242 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P40337 P43686 P48556 P49720 P49721 P51665 P51668 P60896 P60900 P61077 P62191 P62195 P62333 P62837 P62877 P62979 P62987 Q13200 Q13617 Q15008 Q15369 Q15370 Q16186 Q16665 Q96IF1 Q96KS0 Q99436 Q99460 Q99814 Q9GZT9 Q9H6Z9 Q9UGP4 Q9UNM6 Q9Y2N7	ADRM1 AJUBA BHLHE17 BHLHE73 BHLHE78 C1orf12 C7orf76 CUL2 DSS1 EGLN1 EGLN2 EGLN3 EIT6 ELOB ELOC EPAS1 GP110 HC2 HC3 HC8 HC9 HIF1A HIF2A HIF3A HSPC JUB KIAA0107 LIMD1 LMPX LMPY MB1 MIP224 MOP1 MOP2 MOP7 MOV34L MSS1 NU PASD2 PASD7 PASD8 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PUBC1 RBX1 RNF75 ROC1 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TCEB1 TCEB2 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 VHL WTIP X Y Z	Homo sapiens (human)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Aurora kinase A Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/LRR-repeat protein 18 F-box/LRR-repeat protein 7 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O14965 O43242 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q13200 Q13616 Q15008 Q16186 Q96ME1 Q99436 Q99460 Q9UJT9 Q9UNM6	ADRM1 AIK AIRK1 ARK1 AURA AURKA AYK1 BTAK C7orf76 CUL1 DSS1 EMC19 FBL18 FBL6 FBL7 FBXL18 FBXL7 GP110 HC2 HC3 HC8 HC9 HSPC IAK1 KIAA0107 KIAA0840 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A STK15 STK6 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Aurora kinase A Aurora kinase B Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Retinoblastoma-associated protein S-phase kinase-associated protein 2 Securin Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O00762 O14818 O14965 O43242 O95997 P06400 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30260 P35998 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P53350 P60006 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q12834 Q13042 Q13200 Q13309 Q15008 Q16186 Q16763 Q8NHZ8 Q96DE5 Q96GD4 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13 Q9UNM6	ADRM1 AIK AIK2 AIM1 AIRK1 AIRK2 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 ARK1 ARK2 AURA AURKA AURKB AYK1 BTAK C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF EAP1 FBXL1 FYR FZR FZR1 GP110 HC2 HC3 HC8 HC9 HSPC IAK1 KIAA0107 KIAA1242 KIAA1406 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 PLK PLK1 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTTG PTTG1 RB1 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP2 STK1 STK12 STK15 STK5 STK6 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 TUTR1 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Z	Homo sapiens (human)
Separation of Sister Chromatids	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cohesin subunit SA-1 Cohesin subunit SA-2 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Double-strand-break repair protein rad21 homolog Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 SKA complex subunit 1 Securin Separin Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Small ribosomal subunit protein eS27 Sororin Spindle and kinetochore-associated protein 2 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Wings apart-like protein homolog ZW10 interactor	O00139 O00231 O00232 O00487 O00762 O14576 O14777 O14818 O14980 O15392 O43237 O43242 O43264 O43683 O43684 O60216 O60566 O75122 O95229 O95997 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30153 P30154 P30260 P30622 P35998 P36873 P42677 P43034 P43686 P46060 P48556 P49450 P49454 P49720 P49721 P49792 P50748 P51665 P51668 P51965 P53350 P55735 P57740 P60006 P60896 P60900 P62191 P62195 P62333 P62714 P62979 P62987 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13042 Q13200 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14674 Q14683 Q14738 Q15008 Q15172 Q15173 Q15691 Q16186 Q16537 Q16763 Q29RF7 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q7Z5K2 Q8N0S6 Q8N2Z9 Q8N3U4 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NHZ8 Q8NI77 Q8WUM0 Q8WVK7 Q8WVM7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96DE5 Q96EA4 Q96FF9 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99436 Q99460 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H1A4 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NTI5 Q9NXR1 Q9NYG5 Q9P258 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13 Q9UNM6 Q9UQE7 Q9Y266 Q9Y6D9 Q9Y6G9	ADRM1 AHCTF1 AIK2 AIM1 AIRK2 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 API4 APITD1 APRIN ARK2 AS3 AURKB B9D2 BAM BIRC5 BMH BUB1 BUB1B BUB1L BUB3 BUBR1 C10orf104 C11orf51 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 C7orf76 C9orf17 CASC5 CCDC99 CDC16 CDC20 CDC23 CDC26 CDC27 CDCA1 CDCA5 CDCA8 CENP-27 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CSPG6 CYLN1 D0S1430E D17S978E D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DSS1 DXS423E DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 E2EPF EAP1 ELYS EOPA ERCC6L ESP1 ESPL1 FAAP16 FAM33A FOE FSHPRH1 GP110 HC2 HC3 HC8 HC9 HDLC1 HEC HEC1 HR21 HSPC IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0078 KIAA0097 KIAA0107 KIAA0165 KIAA0166 KIAA0178 KIAA0197 KIAA0261 KIAA0325 KIAA0622 KIAA0627 KIAA0648 KIAA0979 KIAA1361 KIAA1406 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LMPX LMPY LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MB1 MCM21R MDCR MDS MHF1 MIP224 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MOV34L MPS1 MSS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NU NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 NXP1 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PDS5 PDS5A PDS5B PESCRG3 PFAAP4 PICH PLK PLK1 PMF1 POH1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTTG PTTG1 RAD21 RANBP2 RANGAP1 RCC2 ROD RPS27 RPS27A RSN SA1 SA2 SB1.8 SCC1 SCC3 SD SEC13 SEC13A SEC13L1 SEC13R SEM1 SFT SGO1 SGO2 SGOL1 SGOL2 SHFDG1 SHFM1 SKA1 SKA2 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STAG1 STAG2 STK1 STK12 STK5 SUG1 SUG2 TAOK1 TBP1 TBP7 TD60 TMBS62 TRAP2 TSG24 TUTR1 TXBP181 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S WAPAL WAPL X XPO1 Y Z ZW10 ZWILCH ZWINT	Homo sapiens (human)
MAPK6/MAPK4 signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cdc42 effector protein 2 Cdc42 effector protein 3 Cdc42 effector protein 5 Cell division control protein 42 homolog Cyclin-dependent kinase 1 DnaJ homolog subfamily B member 1 Dual specificity protein phosphatase CDC14A Dual specificity protein phosphatase CDC14B ETS translocation variant 4 Exportin-1 Forkhead box protein O1 Forkhead box protein O3 G1/S-specific cyclin-D3 Heat shock protein beta-1 Helicase MOV-10 Insulin-like growth factor 2 mRNA-binding protein 1 Kalirin MAP kinase-activated protein kinase 5 Mitogen-activated protein kinase 4 Mitogen-activated protein kinase 6 Myc proto-oncogene protein Nuclear receptor coactivator 3 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Ras-related C3 botulinum toxin substrate 1 Septin-7 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Transcription factor Jun Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein V(D)J recombination-activating protein 1 V(D)J recombination-activating protein 2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00231 O00232 O00487 O14613 O14818 O14980 O43242 O43524 O60229 O60729 O75914 P01106 P04792 P05412 P06493 P0CG47 P0CG48 P15918 P17612 P17980 P20618 P22612 P22694 P25685 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30281 P31152 P35998 P43268 P43686 P48556 P49720 P49721 P51665 P55895 P60896 P60900 P60953 P62191 P62195 P62333 P62979 P62987 P63000 Q12778 Q13153 Q13177 Q13200 Q15008 Q16181 Q16186 Q16659 Q6NZY7 Q8IW41 Q8NDV7 Q99436 Q99460 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9NZI8 Q9UKI2 Q9UKV8 Q9UL18 Q9UNH5 Q9UNM6 Q9UPQ9 Q9Y6Q9	ADRM1 AGO1 AGO2 AGO3 AGO4 AIB1 BHLHE39 BHLHE42 BORG1 BORG2 BORG3 C7orf76 CAGH26 CCND3 CDC10 CDC14A CDC14B CDC2 CDC28A CDC42 CDC42EP2 CDC42EP3 CDC42EP5 CDK1 CDKN1 CEP2 CEP3 CEP5 CRDBP CRM1 DNAJ1 DNAJB1 DSS1 DUET DUO E1AF EIF2C1 EIF2C2 EIF2C3 EIF2C4 ERK3 ERK4 ETV4 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A GP110 HAPIP HC2 HC3 HC8 HC9 HDJ1 HSP27 HSP28 HSPB1 HSPC HSPF1 IGF2BP1 JUN KALRN KIAA0107 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 LMPX LMPY MAPK4 MAPK6 MAPKAPK5 MB1 MIP224 MOV10 MOV34L MSS1 MYC NCOA3 NU OPHN3 P34CDC2 PAK1 PAK2 PAK3 PEA3 PFAAP4 PKACA POH1 PRAK PRKACA PRKACB PRKACG PRKM4 PRKM6 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RAC1 RAC3 RAG1 RAG2 RNF74 RPS27A SEM1 SEPT7 SEPTIN7 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TC25 TNRC6 TNRC6A TNRC6B TNRC6C TRAD TRAM1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VICKZ1 X XPO1 Y Z ZBP1	Homo sapiens (human)
Regulation of RAS by GAPs	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-3 Disabled homolog 2-interacting protein E3 ubiquitin-protein ligase RBX1 GTPase HRas GTPase NRas Kelch repeat and BTB domain-containing protein 7 Neurofibromin Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RAS protein activator like-3 Ras GTPase-activating protein 1 Ras GTPase-activating protein 2 Ras GTPase-activating protein 3 Ras GTPase-activating protein 4 Ras GTPase-activating protein nGAP Ras/Rap GTPase-activating protein SynGAP RasGAP-activating-like protein 1 Sprouty-related, EVH1 domain-containing protein 1 Sprouty-related, EVH1 domain-containing protein 2 Sprouty-related, EVH1 domain-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 O43374 O95294 P01111 P01112 P0CG47 P0CG48 P17980 P20618 P20936 P21359 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 Q13200 Q13618 Q14644 Q15008 Q15283 Q16186 Q2MJR0 Q5VWQ8 Q7Z698 Q7Z699 Q86YV0 Q8WVZ9 Q96PV0 Q99436 Q99460 Q9UJF2 Q9UNM6	ADRM1 AF9Q34 AIP1 C7orf76 CAPRI CUL3 DAB2IP DSS1 EVE-3 GAP GAP1M GAPL GP110 HC2 HC3 HC8 HC9 HRAS HRAS1 HSPC KBTBD7 KIAA0107 KIAA0538 KIAA0617 KIAA1743 KIAA1938 LMPX LMPY MB1 MIP224 MOV34L MSS1 NF1 NGAP NRAS NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RASA RASA1 RASA2 RASA3 RASA4 RASAL RASAL1 RASAL2 RASAL3 RASGAP RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SPRED1 SPRED2 SPRED3 SUG1 SUG2 SYNGAP1 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
Calmodulin induced events	Beta-adrenergic receptor kinase 1 Calmodulin-1 Protein kinase C alpha type Protein kinase C delta type Protein kinase C gamma type	P05129 P0DP23 P17252 P25098 Q05655	ADRBK1 BARK BARK1 CALM CALM1 CAM CAM1 GRK2 PKCA PKCD PKCG PRKACA PRKCA PRKCD PRKCG	Homo sapiens (human)
Activation of SMO	Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Brother of CDO Casein kinase I isoform alpha Cell adhesion molecule-related/down-regulated by oncogenes Desert hedgehog protein Dynein regulatory complex subunit 4 EF-hand calcium-binding domain-containing protein 7 EvC complex member EVC Growth arrest-specific protein 1 IQ domain-containing protein E Indian hedgehog protein Kinesin-like protein KIF3A Limbin Protein patched homolog 1 Protein smoothened Sonic hedgehog protein	A8K855 O43323 O95995 P25098 P32121 P48729 P49407 P54826 P57679 Q13635 Q14623 Q15465 Q4KMG0 Q6IPM2 Q86UK5 Q99835 Q9BWV1 Q9Y496	ADRBK1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BARK BARK1 BOC CDO CDON CSNK1A1 DHH DRC4 EFCAB7 EVC EVC2 GAS1 GAS11 GAS8 GRK2 IHH IQCE KIAA1023 KIAA1799 KIF3 KIF3A LBN PTCH PTCH1 SHH SMO SMOH	Homo sapiens (human)
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P47898 P50406 Q13639	ADRB2RL1 ADRBRL1 HTR1A HTR1B HTR1C HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HTRL	Homo sapiens (human)
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	P08913 P18089 P18825	ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR	Homo sapiens (human)
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor	P07550 P08588 P08913 P13945 P18089 P18825 P25100 P35348 P35368	ADRA1A ADRA1B ADRA1C ADRA1D ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR ADRB1 ADRB1R ADRB2 ADRB2R ADRB3 ADRB3R B1AR B2AR B3AR	Homo sapiens (human)
Sealing of the nuclear envelope (NE) by ESCRT-III	Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Coiled-coil and C2 domain-containing protein 1B IST1 homolog LEM domain-containing protein 2 Putative tubulin-like protein alpha-4B Spastin Tubulin alpha chain-like 3 Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta 8B Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain Tubulin beta-8 chain Vacuolar protein sorting-associated protein 4A	A6NHL2 A6NNZ2 O43633 P04350 P0DPH7 P0DPH8 P53990 P68363 P68366 P68371 Q13509 Q13885 Q3ZCM7 Q5T0F9 Q6PEY2 Q71U36 Q8NC56 Q8WUX9 Q96CF2 Q96FZ7 Q9BQE3 Q9BUF5 Q9BVA1 Q9BY43 Q9H444 Q9H4B7 Q9H853 Q9NY65 Q9UBP0 Q9UN37 Q9UQN3 Q9Y3E7	ADPSP BC2 C14orf123 C20orf178 CC2D1B CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 FSP2 IST1 KIAA0174 KIAA1083 KIAA1836 LEMD2 LGD1 NEDF SHAX1 SHAX2 SHAX3 SPAST SPG4 TUBA1 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA4 TUBA4A TUBA4B TUBA6 TUBA8 TUBAL2 TUBAL3 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6 TUBB8 TUBB8B VPS20 VPS24 VPS4 VPS4A	Homo sapiens (human)
Maturation of nucleoprotein	Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Nucleoprotein Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	P49840 P49841 P59595 P63165 P63279 Q2NL67 Q460N5 Q53GL7 Q8IXQ6 Q8N3A8 Q8N5Y8 Q9UKK3	ADPRTL1 ARTD15 BAL BAL1 BAL2 C15orf30 GSK3A GSK3B KIAA0177 KIAA1268 N PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL SMT3C SMT3H3 SUMO1 UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Maturation of nucleoprotein	Casein kinase I isoform alpha Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Nucleoprotein Protein arginine N-methyltransferase 1 Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 SRSF protein kinase 1 SRSF protein kinase 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	P0DTC9 P48729 P49840 P49841 P63165 P63279 P78362 Q2NL67 Q460N5 Q53GL7 Q8IXQ6 Q8N3A8 Q8N5Y8 Q96SB4 Q99873 Q9UKK3	ADPRTL1 ARTD15 BAL BAL1 BAL2 C15orf30 CSNK1A1 GSK3A GSK3B HMT2 HRMT1L2 IR1B4 KIAA0177 KIAA1268 N PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL PRMT1 SMT3C SMT3H3 SRPK1 SRPK2 SUMO1 UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Nicotinamide salvaging	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase ATP-dependent (S)-NAD(P)H-hydrate dehydratase NAD(P)H-hydrate epimerase NAD-capped RNA hydrolase NUDT12 Nicotinamide N-methyltransferase Nicotinamide phosphoribosyltransferase Nicotinate phosphoribosyltransferase Prostacyclin synthase Prostaglandin G/H synthase 2 Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 Renalase Sodium-coupled monocarboxylate transporter 1 Solute carrier family 22 member 13	P35354 P40261 P43490 Q16647 Q2NL67 Q460N5 Q53GL7 Q5VYX0 Q6XQN6 Q8IW45 Q8IXQ6 Q8N3A8 Q8N5Y8 Q8N695 Q8NCW5 Q9BQG2 Q9UKK3 Q9UNU6 Q9Y226	ADPRTL1 AIBP AIT APOA1BP ARTD15 BAL BAL1 BAL2 C10orf59 C15orf30 CARKD COX2 CYP12 CYP8 CYP8A1 CYP8B1 FHIP KIAA0177 KIAA1268 NAMPT NAPRT NAPRT1 NAXD NAXE NNMT NUDT12 OCTL1 ORCTL3 PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL PBEF PBEF1 PTGIS PTGS2 RNLS SLC22A13 SLC5A8 SMCT SMCT1 YJEFN1	Homo sapiens (human)
Downregulation of SMAD2/3:SMAD4 transcriptional activity	E3 ubiquitin-protein ligase Arkadia E3 ubiquitin-protein ligase NEDD4-like E3 ubiquitin-protein ligase SMURF2 E3 ubiquitin-protein ligase TRIM33 Histone deacetylase 1 Homeobox protein TGIF1 Homeobox protein TGIF2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Poly [ADP-ribose] polymerase 1 Polyubiquitin-B Polyubiquitin-C Protein ATP1B4 Protein phosphatase 1A SNW domain-containing protein 1 Ski oncogene Ski-like protein Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing transcription regulator protein 1	O15105 O75376 P09874 P0CG47 P0CG48 P12755 P12757 P27361 P28482 P35813 P51668 P61077 P62979 P62987 P84022 Q13485 Q13547 Q13573 Q15583 Q15796 Q6ZNA4 Q93008 Q96PU5 Q9GZN2 Q9GZV5 Q9HAU4 Q9UN42 Q9UPN9 Q9Y618	ADPRT ATP1B4 CTG26 DFFRX DPC4 ERK1 ERK2 FAM HDAC1 KIAA0439 KIAA1047 KIAA1113 MADH2 MADH3 MADH4 MADH7 MADH8 MADR2 MAPK1 MAPK3 NCOR1 NCOR2 NEDD4L NEDL3 PARP1 PPM1A PPOL PPPM1A PRKM1 PRKM2 PRKM3 RFG7 RNF111 RPD3L1 RPS27A SFT SKI SKIIP SKIL SKIP SMAD2 SMAD3 SMAD4 SMAD7 SMURF2 SNO SNW1 TAZ TGIF TGIF1 TGIF2 TIF1G TRIM33 UBA52 UBA80 UBB UBC UBC5A UBC5C UBCEP1 UBCEP2 UBCH5 UBCH5A UBCH5C UBE2D1 UBE2D3 USP9 USP9X WWTR1	Homo sapiens (human)
HDR through MMEJ (alt-NHEJ)	Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA ligase 3 DNA polymerase theta DNA repair protein RAD50 DNA repair protein RAD52 homolog DNA repair protein XRCC1 Double-strand break repair protein MRE11 Flap endonuclease 1 Nibrin Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2	O60934 O75417 P09874 P18887 P39748 P43351 P49916 P49959 P51587 Q92878 Q99708 Q9UGN5	ADPRT ADPRT2 ADPRTL2 BRCA2 CTIP FACD FANCD1 FEN1 HNGS1 LIG3 MRE11 MRE11A NBN NBS NBS1 P95 PARP1 PARP2 POLH POLQ PPOL RAD2 RAD50 RAD52 RBBP8 XRCC1	Homo sapiens (human)
Dual Incision in GG-NER	Chromodomain-helicase-DNA-binding protein 1-like Cullin-4A Cullin-4B DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair endonuclease XPF DNA repair protein complementing XP-A cells E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P07992 P09874 P0CG47 P0CG48 P12004 P15927 P18074 P19447 P23025 P27694 P28340 P28715 P32780 P35244 P35249 P35250 P35251 P40937 P40938 P49005 P56282 P62877 P62979 P62987 Q07864 Q13619 Q13620 Q13888 Q13889 Q15054 Q16531 Q6ZYL4 Q86WJ1 Q92466 Q92759 Q92889 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9UGN5	ADPRT ADPRT2 ADPRTL2 ALC1 BTF2 BTF2P44 C6orf175 CHD1L CHRAC17 CUL4A CUL4B DDB1 DDB2 DINB1 DPE2 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0039 KIAA0695 PARP1 PARP2 PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLK PPOL RBX1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 XAP1 XPA XPAC XPB XPBC XPD XPDC XPF XPG XPGC	Homo sapiens (human)
Formation of Incision Complex in GG-NER	CDK-activating kinase assembly factor MAT1 Centrin-2 Chromodomain-helicase-DNA-binding protein 1-like Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA damage-binding protein 2 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA repair endonuclease XPF DNA repair protein complementing XP-A cells DNA repair protein complementing XP-C cells E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 ubiquitin-protein ligase Arkadia E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Polyubiquitin-B Polyubiquitin-C Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 UV excision repair protein RAD23 homolog A UV excision repair protein RAD23 homolog B Ubiquitin carboxyl-terminal hydrolase 45 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O75925 P07992 P09874 P0CG47 P0CG48 P15927 P18074 P19447 P23025 P27694 P28715 P32780 P35244 P41208 P50613 P51946 P51948 P54725 P54727 P55854 P61088 P61956 P62877 P62979 P62987 P63165 P63279 Q01831 Q13619 Q13620 Q13888 Q13889 Q15819 Q16531 Q6ZNA4 Q6ZYL4 Q70EL2 Q86WJ1 Q92466 Q92759 Q92889 Q9UGN5 Q9Y6X2	ADPRT ADPRT2 ADPRTL2 ALC1 BLU BTF2 BTF2P44 C6orf175 CAK CAK1 CALT CAP35 CCNH CDK7 CDKN7 CEN2 CETN2 CHD1L CUL4A CUL4B DDB1 DDB2 DDXBP1 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0695 MAT1 MMS2 MNAT1 MO15 PARP1 PARP2 PIAS1 PIAS3 PPOL RAD23A RAD23B RBX1 REPA1 REPA2 REPA3 RNF111 RNF66 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 STK1 SUMO1 SUMO2 SUMO3 TTDA UBA52 UBA80 UBB UBC UBC9 UBCE9 UBCEP1 UBCEP2 UBE2I UBE2N UBE2V2 UBL1 UEV2 USP45 XAP1 XPA XPAC XPB XPBC XPC XPCC XPD XPDC XPF XPG XPGC	Homo sapiens (human)
POLB-Dependent Long Patch Base Excision Repair	ADP-ribosylhydrolase ARH3 DNA ligase 1 DNA polymerase beta DNA repair nuclease/redox regulator APEX1 Flap endonuclease 1 Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2 Poly(ADP-ribose) glycohydrolase	P06746 P09874 P18858 P27695 P39748 Q86W56 Q9NX46 Q9UGN5	ADPRHL2 ADPRS ADPRT ADPRT2 ADPRTL2 APE APE1 APEX APEX1 APX ARH3 FEN1 HAP1 LIG1 PARG PARP1 PARP2 POLB PPOL RAD2 REF1	Homo sapiens (human)
Acyl chain remodeling of DAG and TAG	1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 Acyl-CoA wax alcohol acyltransferase 2 Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2-like protein 6 Diacylglycerol O-acyltransferase 2 Monoglyceride lipase Patatin-like phospholipase domain-containing protein 2	O75907 Q6E213 Q6ZPD8 Q96AD5 Q96PD7 Q99685 Q9NST1	ADPN AGRP1 ATGL AWAT2 C22orf20 DC3 DC4 DGAT DGAT1 DGAT2 DGAT2L4 DGAT2L6 MFAT MGLL PNPLA2 PNPLA3 WS	Homo sapiens (human)
Glycolysis	ADP-dependent glucokinase ATP-dependent 6-phosphofructokinase, liver type ATP-dependent 6-phosphofructokinase, muscle type ATP-dependent 6-phosphofructokinase, platelet type Alpha-enolase Beta-enolase Bisphosphoglycerate mutase Enolase 4 Fructose-bisphosphate aldolase A Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase C Gamma-enolase Glucosamine-6-phosphate isomerase 1 Glucosamine-6-phosphate isomerase 2 Glucose 1,6-bisphosphate synthase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase, testis-specific Glyceraldehyde-3-phosphate dehydrogenase Glycerol-3-phosphate phosphatase Hexokinase HKDC1 Hexokinase-1 Hexokinase-2 Hexokinase-3 Hexokinase-4 Phosphoglycerate kinase 1 Phosphoglycerate kinase 2 Phosphoglycerate mutase 1 Phosphoglycerate mutase 2 Triosephosphate isomerase	A6NDG6 A6NNW6 O14556 P00558 P04075 P04406 P05062 P06733 P06744 P07205 P07738 P08237 P09104 P09972 P13929 P15259 P17858 P18669 P19367 P35557 P46926 P52789 P52790 P60174 Q01813 Q2TB90 Q6PCE3 Q8TDQ7 Q9BRR6	ADPGK ALDA ALDB ALDC ALDOA ALDOB ALDOC BM32A BPGM C10orf134 ENO1 ENO1L1 ENO2 ENO3 ENO4 GAPD GAPD2 GAPDH GAPDH2 GAPDHS GAPDS GCK GNP2 GNPDA1 GNPDA2 GNPI GPI HK1 HK2 HK3 HKDC1 HLN KIAA0060 MBPB1 MPB1 PFKF PFKL PFKM PFKP PFKX PGAM1 PGAM2 PGAMA PGAMM PGK1 PGK2 PGKA PGKB PGM2L1 PGP TPI TPI1	Homo sapiens (human)	G58161NS
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2a Adenosine receptor A2b Adenosine receptor A3	P0DMS8 P29274 P29275 P30542	ADORA1 ADORA2 ADORA2A ADORA2B ADORA3	Homo sapiens (human)
Degradation of cysteine and homocysteine	2-aminoethanethiol dioxygenase 3-mercaptopyruvate sulfurtransferase Acidic amino acid decarboxylase GADL1 Aspartate aminotransferase, mitochondrial Cystathionine gamma-lyase Cysteine dioxygenase type 1 Cysteine sulfinic acid decarboxylase Flavin-containing monooxygenase 1 Thioredoxin, mitochondrial Thiosulfate sulfurtransferase	P00505 P25325 P32929 Q01740 Q16762 Q16878 Q6ZQY3 Q96SZ5 Q99757 Q9Y600	ADO C10orf22 CDO1 CSAD CSD CTH FMO1 GADL1 GOT2 KYAT4 MPST TRX2 TST TST2 TXN2	Homo sapiens (human)

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