TICAM1, RIP1-mediated IKK complex recruitment
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- API1
- API2
- BIRC2
- BIRC3
- BLU
- CHUK
- CROC1
- FIP3
- IKBKB
- IKBKG
- IKKA
- IKKB
- MIHB
- MIHC
- NEMO
- PRVTIRB
- PUBC1
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- RNF48
- RNF49
- RNF85
- RPS27A
- SFT
- TCF16
- TICAM1
- TLR3
- TRAF6
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBC5A
- UBC5B
- UBC5C
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5
- UBCH5A
- UBCH5B
- UBCH5C
- UBE2D1
- UBE2D2
- UBE2D3
- UBE2N
- UBE2V
- UBE2V1
- UEV1
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TICAM1 deficiency - HSE
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TGFBR2 MSI Frameshift Mutants in Cancer
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TGFBR2 Kinase Domain Mutants in Cancer
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- ALK5
- SKR4
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
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TGFBR1 LBD Mutants in Cancer
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- ALK5
- FKBP1
- FKBP12
- FKBP1A
- SKR4
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
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TGFBR1 KD Mutants in Cancer
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- ALK5
- MADH2
- MADH3
- MADR2
- SKR4
- SMAD2
- SMAD3
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
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TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
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- ALK5
- ARH12
- ARHA
- ARHGEF18
- CGN
- F11R
- FKBP1
- FKBP12
- FKBP1A
- JAM1
- JCAM
- KIAA0521
- KIAA1319
- KIAA1625
- PAR3
- PAR3A
- PAR6A
- PARD3
- PARD6A
- PKC2
- PRKCZ
- RHO12
- RHOA
- RPS27A
- SKR4
- SMURF1
- TGFB
- TGFB1
- TGFBR1
- TGFBR2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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TGF-beta receptor signaling activates SMADs
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- ALK5
- C14orf141
- CBL
- CBL2
- DPC4
- FKBP1
- FKBP12
- FKBP1A
- FNRB
- FUR
- FURIN
- GP3A
- ITGA8
- ITGAV
- ITGB1
- ITGB3
- ITGB5
- ITGB6
- ITGB8
- LTBP1
- LTBP2
- LTBP3
- LTBP4
- MADH2
- MADH3
- MADH4
- MADR2
- MDF2
- MSK12
- MSK8
- NEDD8
- PACE
- PCSK3
- RNF55
- SKR4
- SMAD2
- SMAD3
- SMAD4
- TGFB
- TGFB1
- TGFB2
- TGFB3
- TGFBR1
- TGFBR2
- TGFBR3
- UBC12
- UBE2M
- VNRA
- VTNR
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TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
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- AP2TF
- BMYB
- HSP60
- HSPD1
- MYBL2
- NOL1
- NOP2
- NPM
- NPM1
- NSUN1
- TFAP2
- TFAP2A
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TFAP2 (AP-2) family regulates transcription of other transcription factors
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- AP2TF
- ARP1
- CITED2
- MRG1
- PITX2
- RGS
- RIEG
- RIEG1
- TFAP2
- TFAP2A
- TFAP2C
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TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
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- AP2TF
- ATAD2
- CGA
- CGB
- CGB3
- CGB5
- CGB8
- EGFR
- ERBB
- ERBB1
- ERBB2
- ESR
- ESR1
- HER1
- HER2
- INO80S
- KIT
- MLN19
- NEU
- NGL
- NR3A1
- SCFR
- TFAP2
- TFAP2A
- TFAP2B
- TFAP2C
- TGFA
- VEGF
- VEGFA
- YY1
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TFAP2 (AP-2) family regulates transcription of cell cycle factors
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- AP2TF
- BHLHE39
- CAP20
- CDKN1
- CDKN1A
- CIP1
- JARID1B
- KDM5B
- MDA6
- MYC
- PIC1
- PLU1
- RBBP2H1
- SDI1
- TFAP2
- TFAP2A
- TFAP2C
- WAF1
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TCF dependent signaling in response to WNT
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- AXIN
- AXIN1
- AXIN2
- CTNNB
- CTNNB1
- DKK1
- DKK2
- DKK4
- DVL1
- DVL2
- DVL3
- FRP
- FRP1
- FRP2
- FZD1
- FZD2
- INT1
- INT4
- JTK5A
- KIAA0208
- KIAA0570
- KIAA0729
- KREMEN
- KREMEN1
- KREMEN2
- KRM1
- KRM2
- LR3
- LRP5
- LRP6
- LRP7
- PARP5A
- PARP5B
- PARPL
- RNF146
- RPS27A
- RYK
- SARP1
- SARP2
- SFRP1
- SFRP2
- SOST
- TANK2
- TIN1
- TINF1
- TNKL
- TNKS
- TNKS1
- TNKS2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- USP34
- WIF1
- WNT1
- WNT14
- WNT3
- WNT3A
- WNT4
- WNT5A
- WNT8A
- WNT8B
- WNT8D
- WNT9A
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TBC/RABGAPs
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- ARF6
- C20orf140
- EPI64
- FIP2
- FLC3A
- FLC3B
- GABARAP
- GABARAPL2
- GEF2
- GGA1
- GGA2
- GGA3
- GLC1E
- HIP7
- HYPL
- KIAA0154
- KIAA0243
- KIAA0722
- KIAA1080
- KIAA1171
- KIAA1322
- MAP1ALC3
- MAP1LC3B
- MEL
- NRP
- OATL1
- OPTN
- PARIS1
- PP8997
- PRC17
- RAB11
- RAB11A
- RAB11B
- RAB1C
- RAB33A
- RAB33B
- RAB35
- RAB4
- RAB4A
- RAB5
- RAB5A
- RAB5B
- RAB5C
- RAB5EP
- RAB6
- RAB6A
- RAB6B
- RAB7
- RAB7A
- RAB7B
- RAB8
- RAB8A
- RAB8B
- RABEP1
- RABEX5
- RABGAP1
- RABGEF1
- RABL
- RABPT5
- RABPT5A
- RABS10
- RAY
- SLP1
- SYTL1
- TBC1D10
- TBC1D10A
- TBC1D10B
- TBC1D10C
- TBC1D13
- TBC1D14
- TBC1D15
- TBC1D16
- TBC1D17
- TBC1D2
- TBC1D20
- TBC1D24
- TBC1D25
- TBC1D2A
- TBC1D3
- TBC1D3A
- TBC1D7
- TBC7
- TSC
- TSC1
- TSC2
- TSC4
- ULK1
- YPT3
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TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P
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TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P
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TAK1-dependent IKK and NF-kappa-B activation
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- A4
- AD1
- AGER
- ALPK1
- APP
- BLU
- CARD15
- CARD4
- CARDIAK
- CHUK
- CROC1
- FIP3
- HMG1
- HMGB1
- IKBA
- IKBB
- IKBKB
- IKBKG
- IKKA
- IKKB
- IRAK
- IRAK1
- IRAK2
- ISG43
- KBRAS1
- KBRAS2
- KIAA0733
- KIAA1527
- LAK
- LYT10
- MAD3
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- N
- NEMO
- NFKB1
- NFKB2
- NFKB3
- NFKBI
- NFKBIA
- NFKBIB
- NKIRAS1
- NKIRAS2
- NOD1
- NOD2
- RAGE
- RELA
- RICK
- RIP2
- RIPK2
- RNF85
- RPS27A
- S100A12
- S100B
- SAA1
- T2BP
- TAB1
- TAB2
- TAB3
- TAK1
- TCF16
- TIFA
- TRAF6
- TRIP9
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBE2N
- UBE2V
- UBE2V1
- UEV1
- USP18
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Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
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- ADCP2
- AN2
- CD26
- DPP4
- FFAR1
- GATA4
- GIP
- GPR119
- GPR40
- ISL1
- KIAA0102
- NEC1
- PAX6
- PCSK1
- SEC11A
- SEC11C
- SEC11L1
- SEC11L3
- SPC12
- SPC18
- SPC21
- SPC22
- SPC25
- SPCS1
- SPCS2
- SPCS3
- SPCS4A
- SPCS4C
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Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
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- ADCP2
- AN2
- CD26
- CDX2
- CDX3
- CTNNB
- CTNNB1
- DPP4
- FFAR1
- FFAR4
- GCG
- GNAT3
- GNB1
- GNB3
- GNG13
- GPR119
- GPR120
- GPR129
- GPR40
- GRP
- KIAA0102
- LEP
- NEC1
- O3FAR1
- OB
- OBS
- PAX6
- PCSK1
- PGR4
- SEC11A
- SEC11C
- SEC11L1
- SEC11L3
- SPC12
- SPC18
- SPC21
- SPC22
- SPC25
- SPCS1
- SPCS2
- SPCS3
- SPCS4A
- SPCS4C
- TCF4
- TCF7L2
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Synthesis, secretion, and deacylation of Ghrelin
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- ACHE
- BCHE
- CHE1
- CRF2R
- CRH2R
- CRHR2
- EZF
- GCG
- GH1
- GKLF
- GOAT
- IBP1
- IGF1
- INS
- KIAA0102
- KLF4
- LEP
- MBOAT4
- NEC1
- OACT4
- OB
- OBS
- PAFAH
- PCSK1
- PLA2G7
- SEC11A
- SEC11C
- SEC11L1
- SEC11L3
- SPC12
- SPC18
- SPC21
- SPC22
- SPC25
- SPCS1
- SPCS2
- SPCS3
- SPCS4A
- SPCS4C
- UCN
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Synthesis of wybutosine at G37 of tRNA(Phe)
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- C1orf171
- C2orf60
- KIAA0547
- KIAA1393
- LCMT2
- RSAFD1
- TRM12
- TRM5
- TRMT12
- TRMT5
- TYW1
- TYW2
- TYW3
- TYW4
- TYW5
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Synthesis of very long-chain fatty acyl-CoAs
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- ACS2
- ACS3
- ACS4
- ACS5
- ACSBG1
- ACSBG2
- ACSF3
- ACSL1
- ACSL3
- ACSL4
- ACSL5
- ACSL6
- ACSVL3
- BGM
- BGR
- BIND1
- CIG30
- EDH17B3
- ELG3
- ELOVL1
- ELOVL2
- ELOVL3
- ELOVL4
- ELOVL5
- ELOVL6
- ELOVL7
- FACE
- FACL1
- FACL2
- FACL3
- FACL4
- FACL5
- FACL6
- FATP3
- GPSN2
- HACD1
- HACD2
- HACD3
- HACD4
- HSD17B12
- HSD17B3
- KIAA0631
- KIAA0837
- LACS
- LACS1
- LACS2
- LACS3
- LACS4
- LACS5
- LCE
- LPD
- PTPLA
- PTPLAD1
- PTPLAD2
- PTPLB
- SC2
- SDR12C1
- SDR12C2
- SLC27A3
- SRD5A2L2
- SSC1
- SSC2
- TECR
- TECRL
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Synthesis of pyrophosphates in the cytosol
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- APS1
- APS2
- C9orf12
- DIPP
- DIPP1
- DIPP2
- DIPP3A
- DIPP3B
- HISPPD1
- HISPPD2A
- IHPK1
- IHPK3
- IP6K
- IP6K1
- IP6K3
- IPPK
- IPS1
- ITPK1
- KIAA0263
- KIAA0377
- KIAA0433
- KIAA0487
- NUDT10
- NUDT11
- NUDT3
- NUDT4
- PPIP5K1
- PPIP5K2
- VIP1
- VIP2
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Synthesis of glycosylphosphatidylinositol (GPI)
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- DCRC
- DPM2
- DSCR5
- DSCRC
- GPI2
- GPI7
- MCD4
- PIGA
- PIGB
- PIGC
- PIGF
- PIGG
- PIGH
- PIGL
- PIGM
- PIGN
- PIGO
- PIGP
- PIGV
- PIGW
- PIGX
- PIGY
- PIGZ
- SMP3
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Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
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- CYP1A1
- CYP1A2
- CYP1B1
- CYP2C10
- CYP2C19
- CYP2C8
- CYP2C9
- CYP2J2
- EPHX2
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