GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **976 - 1000** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
HSF1 activation	14-3-3 protein epsilon Elongation factor 1-alpha 1 Heat shock factor protein 1 Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Histone deacetylase 6 Prostaglandin E synthase 3 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Transitional endoplasmic reticulum ATPase	O75506 P07900 P08238 P15927 P27694 P35244 P55072 P62258 P68104 Q00613 Q15185 Q9UBN7	EEF1A EEF1A1 EF1A HDAC6 HEL-220 HEL-S-70 HSBP1 HSF1 HSF1BP HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB HSTF1 KIAA0901 LENG7 P23 PTGES3 REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 TEBP VCP YWHAE
Reactions specific to the hybrid N-glycan synthesis pathway	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Q09327	GGNT3 MGAT3
Toxicity of botulinum toxin type D (botD)	Botulinum neurotoxin type D Synaptic vesicle glycoprotein 2A Synaptic vesicle glycoprotein 2B Synaptic vesicle glycoprotein 2C Vesicle-associated membrane protein 1 Vesicle-associated membrane protein 2	P19321 P23763 P63027 Q496J9 Q7L0J3 Q7L1I2	KIAA0735 KIAA0736 KIAA1054 SV2A SV2B SV2C SYB1 SYB2 VAMP1 VAMP2 botD
Sulfur amino acid metabolism	Adenosylhomocysteinase Betaine--homocysteine S-methyltransferase 1 Methionine synthase reductase Methionine synthase S-adenosylmethionine synthase isoform type-1 S-methylmethionine--homocysteine S-methyltransferase BHMT2	P23526 Q00266 Q93088 Q99707 Q9H2M3 Q9UBK8	AHCY AMS1 BHMT BHMT2 MAT1A MATA1 MTR MTRR SAHH
Downregulation of ERBB2 signaling	Cullin-5 E3 ubiquitin-protein ligase CHIP Epidermal growth factor receptor Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Megakaryocyte-associated tyrosine-protein kinase Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type 18 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14511 O14944 P00533 P01133 P04626 P07900 P0CG47 P0CG48 P35070 P42679 P56975 P62979 P62987 Q02297 Q05209 Q16543 Q8WWG1 Q93034 Q96RT1 Q99075 Q99952 Q9UNE7	BDP1 BTC CDC37 CDC37A CHIP CTK CUL5 DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG GGF HBEGF HEGFL HER1 HER2 HGL HRGA HSP90A HSP90AA1 HSPC1 HSPCA HYL KIAA1225 LAP2 MATK MLN19 NDF NEU NGL NRG1 NRG2 NRG3 NRG4 NTAK PTPN12 PTPN18 RPS27A SMDF STUB1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VACM1
Peroxisomal protein import	2-Hydroxyacid oxidase 1 2-Hydroxyacid oxidase 2 2-hydroxyacyl-CoA lyase 1 3-ketoacyl-CoA thiolase, peroxisomal AN1-type zinc finger protein 6 Acyl-coenzyme A diphosphatase NUDT19 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 8 Alanine--glyoxylate aminotransferase Alkyldihydroxyacetonephosphate synthase, peroxisomal Alpha-methylacyl-CoA racemase Bifunctional epoxide hydrolase 2 Bile acid-CoA Carnitine O-acetyltransferase Catalase D-amino-acid oxidase D-aspartate oxidase Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Glutathione S-transferase kappa 1 Hydroxymethylglutaryl-CoA lyase, mitochondrial Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] cytoplasmic Lon protease homolog 2, peroxisomal Long-chain fatty acid transport protein 2 Nitric oxide synthase, inducible Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal ATPase PEX1 Peroxisomal ATPase PEX6 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal bifunctional enzyme Peroxisomal carnitine O-octanoyltransferase Peroxisomal coenzyme A diphosphatase NUDT7 Peroxisomal leader peptide-processing protease Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal multifunctional enzyme type 2 Peroxisomal sarcosine oxidase Peroxisomal succinyl-coenzyme A thioesterase Peroxisomal targeting signal 2 receptor Peroxisomal trans-2-enoyl-CoA reductase Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Phytanoyl-CoA dioxygenase, peroxisomal Polyubiquitin-B Polyubiquitin-C Protein Mpv17 Sterol carrier protein 2 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MXV4 O00116 O00623 O00628 O14734 O14832 O14975 O15228 O15254 O43933 O60683 O75381 O75874 P04040 P09110 P0C024 P0CG47 P0CG48 P14735 P14920 P21549 P22307 P28328 P34913 P35228 P35914 P39210 P43155 P49753 P51659 P51668 P61077 P62837 P62979 P62987 Q08426 Q13011 Q13608 Q14032 Q15067 Q2T9J0 Q6FIF0 Q6QHF9 Q7Z412 Q86WA8 Q8N9L9 Q92968 Q93008 Q99424 Q99489 Q9BTZ2 Q9BY49 Q9NUI1 Q9NYQ3 Q9P0Z9 Q9UHK6 Q9UJ83 Q9UJM8 Q9UKG9 Q9Y2Q3	ACAA ACAA1 ACOT2 ACOT4 ACOT8 ACOX ACOX1 ACOX2 ACOX3 ACSVL1 ACTEIII AGPS AGT1 AGXT AMACR AWP1 BAAT BRCOX CAT CAT1 COT CRAT CROT DAMOX DAO DAPAT DDO DECR2 DFFRX DHAPAT DHRS4 ECH1 ECHD EDH17B4 EHHADH EPHX2 FACVL1 FAM FATP2 GNPAT GOX1 GSTK1 HACL1 HAO1 HAO2 HAOX2 HMGCL HPCL HPCL2 HSD17B4 IDE IDH1 LONP LONP2 LPIPOX MPV17 NOS2 NOS2A NUDT19 NUDT7 PAF1 PAF3 PAHX PAO PAOX PDCR PECR PEX1 PEX10 PEX12 PEX13 PEX14 PEX2 PEX26 PEX6 PEX7 PHYH PHYH2 PICD PIPOX PMP3 PMP35 PRCOX PSO PTE1 PTE2 PTE2A PTE2B PTEIB PTHIO PTS2R PUBC1 PXAAA1 PXMP3 RNF69 RNF72 RPS27A SCP2 SDR17C1 SDR25C2 SDR29C1 SDR8C1 SFT SLC27A2 SPAT TYSND1 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 USP9 USP9X VLACS ZA20D3 ZFAND6
Replication of the SARS-CoV-1 genome	Probable ATP-dependent RNA helicase DDX5 Replicase polyprotein 1a Replicase polyprotein 1ab Retinoblastoma-associated protein Zinc finger CCHC-type and RNA-binding motif-containing protein 1 von Hippel-Lindau disease tumor suppressor	P06400 P0C6U8 P0C6X7 P17844 P40337 Q8TBF4	1a DDX5 G17P1 HELR HLR1 RB1 VHL ZCRB1 rep
RHOT2 GTPase cycle	Mitochondrial Rho GTPase 2 Mitofusin-1 Mitofusin-2 Rap1 GTPase-GDP dissociation stimulator 1 Trafficking kinesin-binding protein 1 Trafficking kinesin-binding protein 2 Unconventional myosin-XIX	O60296 O95140 P52306 Q8IWA4 Q8IXI1 Q96H55 Q9UPV9	ALS2CR3 ARHT2 C16orf39 CPRP1 KIAA0214 KIAA0549 KIAA1042 MFN1 MFN2 MYO19 MYOHD1 OIP106 RAP1GDS1 RHOT2 SMGGDS TRAK1 TRAK2
BMAL1:CLOCK,NPAS2 activates circadian gene expression	3'-5' exoribonuclease HELZ2 Basic helix-loop-helix ARNT-like protein 1 Basic helix-loop-helix ARNT-like protein 2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Class E basic helix-loop-helix protein 40 Class E basic helix-loop-helix protein 41 Coagulation factor VII D site-binding protein F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Histone-arginine methyltransferase CARM1 Krueppel-like factor 15 Mediator of RNA polymerase II transcription subunit 1 Neuronal PAS domain-containing protein 2 Nicotinamide phosphoribosyltransferase Nocturnin Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Peroxisome proliferator-activated receptor alpha Plasminogen activator inhibitor 1 Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Trimethylguanosine synthase Vasopressin-neurophysin 2-copeptin	O00327 O14503 O15516 O60907 P01185 P05121 P08709 P19793 P43490 Q07869 Q10586 Q14686 Q15596 Q15648 Q15788 Q3L8U1 Q6STE5 Q86X55 Q8WYA1 Q92793 Q96RS0 Q99743 Q9BYK8 Q9BZK7 Q9C0J9 Q9UIH9 Q9UK39	AIB3 ARC205 ARNTL ARNTL2 ARVP AVP BAF60C BHLHB2 BHLHB3 BHLHE40 BHLHE41 BHLHE5 BHLHE6 BHLHE74 BHLHE75 BHLHE8 BHLHE9 BMAL1 BMAL2 CARM1 CBP CCR4 CCRN4L CHD9 CLIF CLOCK CREBBP CRSP1 CRSP200 DBP DEC1 DEC2 DRIP205 DRIP230 F7 HCA137 HELZ2 IRA1 KIAA0181 KIAA0308 KIAA0334 KIAA1769 KISH2 KKLF KLF15 MED1 MOP3 MOP4 MOP9 NAMPT NCOA1 NCOA2 NCOA6 NCOA6IP NOC NOCT NPAS2 NR1C1 NR2B1 PAI1 PASD3 PASD4 PASD9 PBEF PBEF1 PBP PIMT PLANH1 PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SERPINE1 SHARP1 SHARP2 SMARCD3 SRC1 SRC2 STRA13 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2 VP
Glyoxylate metabolism and glycine degradation	2-Hydroxyacid oxidase 1 4-hydroxy-2-oxoglutarate aldolase, mitochondrial Alanine--glyoxylate aminotransferase 2, mitochondrial Alanine--glyoxylate aminotransferase Aspartate aminotransferase, mitochondrial D-amino-acid oxidase D-aspartate oxidase Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial Glycine N-methyltransferase Glyoxylate reductase/hydroxypyruvate reductase Hydroxyproline dehydrogenase Peroxisomal membrane protein 2	P00505 P14920 P21549 P30038 Q14749 Q86XE5 Q99489 Q9BYV1 Q9NR77 Q9UBQ7 Q9UF12 Q9UJM8	AGT1 AGT2 AGXT AGXT2 ALDH4 ALDH4A1 C10orf65 DAMOX DAO DDO DHDPSL GLXR GNMT GOT2 GOX1 GRHPR HAO1 HOGA1 HSPOX1 HYPDH KYAT4 P5CDH PMP22 PRODH2 PXMP2 SPAT
MPS I - Hurler syndrome	Alpha-L-iduronidase	P35475	IDUA
Regulation of IFNG signaling	E3 SUMO-protein ligase PIAS1 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6	O14543 O15524 O60674 O75925 P01579 P15260 P18031 P23458 P29350 P38484 P63165 Q06124	CIS3 DDXBP1 HCP IFNG IFNGR1 IFNGR2 IFNGT1 JAK1 JAK1A JAK1B JAK2 PIAS1 PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SMT3C SMT3H3 SOCS1 SOCS3 SSI1 SSI3 SUMO1 TIP3 UBL1
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	Cyclin-A2 Cyclin-dependent kinase 1 Histone deacetylase 1 Histone-binding protein RBBP4 Myb-related protein B Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5	P06493 P10244 P20248 P28749 Q01094 Q08999 Q09028 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3	BARA BMYB C14orf46 CCN1 CCNA CCNA2 CDC2 CDC28A CDK1 CDKN1 CXCDC1 DP1 DP2 E2F1 E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MYBL2 P34CDC2 RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS
RUNX3 regulates BCL2L11 (BIM) transcription	Bcl-2-like protein 11 Forkhead box protein O3 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor 3	O43521 O43524 P84022 Q13485 Q13761	AML2 BCL2L11 BIM CBFA3 DPC4 FKHRL1 FOXO3 FOXO3A MADH3 MADH4 PEBP2A3 RUNX3 SMAD3 SMAD4
Glucuronidation	Palmitoyl-protein thioesterase ABHD10, mitochondrial UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A10 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A4 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 1A7 UDP-glucuronosyltransferase 1A8 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2A1 UDP-glucuronosyltransferase 2A2 UDP-glucuronosyltransferase 2A3 UDP-glucuronosyltransferase 2B10 UDP-glucuronosyltransferase 2B11 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B28 UDP-glucuronosyltransferase 2B4 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase 3A1 UDP-glucuronosyltransferase 3A2	O60656 O75310 O75795 P06133 P0DTE4 P0DTE5 P16662 P19224 P22309 P22310 P35503 P35504 P36537 P54855 Q3SY77 Q6NUS8 Q6UWM9 Q9BY64 Q9HAW7 Q9HAW8 Q9HAW9 Q9NUJ1	ABHD10 GNT1 UGT1 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UGT2B8 UGT3A1 UGT3A2 UGTB2B9
Activation of the phototransduction cascade	Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Sodium/potassium/calcium exchanger 1	O60721 P08100 P10523 P11488 P16499 P18545 P29973 P35913 P62873 P63211 Q14028	CNCG CNCG1 CNCG2 CNCG3L CNCG4 CNGA1 CNGB1 GNAT1 GNATR GNB1 GNGT1 KIAA0702 NCKX1 OPN2 PDE6A PDE6B PDE6G PDEA PDEB PDEG RCNC2 RHO SAG SLC24A1
Formation of the ternary complex, and subsequently, the 43S complex	Eukaryotic translation initiation factor 1A, X-chromosomal Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Ribosomal protein eS27-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00303 O15371 O15372 O75821 O75822 P05198 P08708 P08865 P15880 P20042 P22090 P23396 P25398 P39019 P41091 P42677 P46781 P46782 P46783 P47813 P55884 P60228 P60866 P61247 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62701 P62753 P62841 P62847 P62851 P62854 P62857 P62861 P62979 P63220 Q13347 Q14152 Q71UM5 Q7L2H7 Q8TD47 Q99613 Q9UBQ5 Q9Y262	CCG2 D6S218E EIF1A EIF1AX EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3C EIF3D EIF3E EIF3EIP EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF3S1 EIF3S10 EIF3S12 EIF3S2 EIF3S3 EIF3S4 EIF3S5 EIF3S6 EIF3S6IP EIF3S7 EIF3S8 EIF3S9 EIF4C FAU FTE1 HFLB5 INT6 KIAA0139 LAMBR LAMR1 MFTL MPS1 PCID1 RIG RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA SCAR TRIP1 UBA80 UBCEP1
Miscellaneous substrates	Cytochrome P450 2D6 Cytochrome P450 2S1 Cytochrome P450 2U1 Cytochrome P450 2W1 Cytochrome P450 3A43 Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F2 Cytochrome P450 4F3 Ultra-long-chain fatty acid omega-hydroxylase	P10635 P13584 P78329 Q02928 Q08477 Q5TCH4 Q6NT55 Q7Z449 Q8TAV3 Q96SQ9 Q9HB55 Q9HBI6	CYP2D6 CYP2DL1 CYP2S1 CYP2U1 CYP2W1 CYP3A43 CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F2 CYP4F22 CYP4F3 LTB4H
Synthesis of wybutosine at G37 of tRNA(Phe)	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 tRNA (guanine(37)-N1)-methyltransferase tRNA wybutosine-synthesizing protein 2 homolog tRNA wybutosine-synthesizing protein 3 homolog tRNA wybutosine-synthesizing protein 4 tRNA wybutosine-synthesizing protein 5	A2RUC4 O60294 Q32P41 Q53H54 Q6IPR3 Q9NV66	C1orf171 C2orf60 KIAA0547 KIAA1393 LCMT2 RSAFD1 TRM12 TRM5 TRMT12 TRMT5 TYW1 TYW2 TYW3 TYW4 TYW5
MET receptor recycling	ADP-ribosylation factor 6 ADP-ribosylation factor-binding protein GGA3 Adapter molecule crk Crk-like protein GRB2-associated-binding protein 1 Hepatocyte growth factor receptor Hepatocyte growth factor Ras-related protein Rab-4A Ras-related protein Rab-4B	P08581 P14210 P20338 P46108 P46109 P61018 P62330 Q13480 Q9NZ52	ARF6 CRK CRKL GAB1 GGA3 HGF HPTA KIAA0154 MET RAB4 RAB4A RAB4B
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 5'-3' exonuclease PLD4 Calmodulin-1 Inositol polyphosphate 5-phosphatase OCRL Inositol-tetrakisphosphate 1-kinase Inositol-trisphosphate 3-kinase A Inositol-trisphosphate 3-kinase B Inositol-trisphosphate 3-kinase C Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Synaptojanin-1 Type II inositol 1,4,5-trisphosphate 5-phosphatase	O15357 O43426 O75038 P0DP23 P16885 P19174 P23677 P27987 P32019 P51178 P60484 Q00722 Q01968 Q01970 Q13572 Q15147 Q15735 Q4KWH8 Q86YW0 Q8N3E9 Q92835 Q96BZ4 Q96DU7 Q9BRC7 Q9NQ66 Q9P212	C14orf175 CALM CALM1 CAM CAM1 INPP5B INPP5D INPP5J INPPL1 IP3KC ITPK1 ITPKA ITPKB ITPKC KIAA0450 KIAA0581 KIAA0910 KIAA1069 KIAA1516 KIAA1964 MMAC1 OCRL OCRL1 OCRL2 PIB5PA PIPP PLC1 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE PLCE1 PLCG1 PLCG2 PLCH1 PLCH2 PLCL3 PLCL4 PLCZ1 PLD4 PPLC PTEN SHIP SHIP1 SHIP2 SYNJ1 TEP1
RHOF GTPase cycle	A-kinase anchor protein 12 Actin, cytoplasmic 1 Alpha-actinin-1 Ankyrin repeat domain-containing protein SOWAHC BAR/IMD domain-containing adapter protein 2-like 1 BAR/IMD domain-containing adapter protein 2-like 2 Brain acid soluble protein 1 Caveolin-1 Cell surface glycoprotein MUC18 DEP domain-containing protein 1B Extended synaptotagmin-1 F-actin-capping protein subunit beta FERM, ARHGEF and pleckstrin domain-containing protein 1 Gamma-adducin Lamin-B1 Lamina-associated polypeptide 2, isoforms beta/gamma Metalloreductase STEAP3 Myotubularin-related protein 1 POTE ankyrin domain family member E Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein diaphanous homolog 1 Protein diaphanous homolog 2 Protein diaphanous homolog 3 Ras-related protein Rab-7a Rho GTPase-activating protein 12 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 32 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein SYDE1 Rho-related GTP-binding protein RhoF SLIT-ROBO Rho GTPase-activating protein 2 Sentrin-specific protease 1 Sodium bicarbonate cotransporter 3 Soluble lamin-associated protein of 75 kDa Synaptosomal-associated protein 23 Torsin-1A-interacting protein 1 Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3	A7KAX9 O00161 O00459 O60610 O60879 O75044 P12814 P20700 P27986 P42167 P43121 P47756 P51149 P60709 P80723 Q02952 Q03135 Q07960 Q13017 Q13459 Q13613 Q15836 Q53LP3 Q5JTV8 Q5T5U3 Q658P3 Q6S8J3 Q6UXY1 Q6ZW31 Q8IWW6 Q8TAA9 Q8WUY9 Q9BSJ8 Q9C0H5 Q9HBH0 Q9NSV4 Q9P0U3 Q9UEY8 Q9UHR4 Q9Y4F1 Q9Y6M7 Q9Y6X4	A26C1A ACTB ACTN1 ADD3 ADDL AKAP12 AKAP250 ANKRD57 ARHF ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP21 ARHGAP32 ARHGAP34 ARHGAP39 ARHGAP5 BAIAP2L1 BAIAP2L2 BASP1 BT C2orf26 CAPZB CAV CAV1 CDC42GAP CDEP DEPDC1B DIA DIAP1 DIAP3 DIAPH1 DIAPH2 DIAPH3 ESYT1 FAM169A FAM62A FARP1 FNBP2 GRB1 GRIT IRTKS KIAA0456 KIAA0712 KIAA0747 KIAA0888 KIAA1424 KIAA1688 LAP1 LAP2 LMN2 LMNB LMNB1 MBC2 MCAM MTMR1 MUC18 MYO9B MYR5 NAP22 NBC2 NBC2B NBC3 NBCn1 PIK3R1 PIK3R2 PLEKHC2 POTE2 POTEE RAB7 RAB7A RHOF RHOGAP1 RHOGAP5 RICS RIF SBC2 SENP1 SLC4A6 SLC4A7 SNAP23 SOWAHC SRGAP2 SRGAP2A STB2 STEAP3 SYB3 SYDE1 TMPO TOR1AIP1 TSAP6 VAMP3 VANGL1 XTP8
Signalling to p38 via RIT and RIN	Beta-nerve growth factor GTP-binding protein Rit1 GTP-binding protein Rit2 High affinity nerve growth factor receptor Serine/threonine-protein kinase B-raf	P01138 P04629 P15056 Q92963 Q99578	BRAF BRAF1 MTC NGF NGFB NTRK1 RAFB1 RIBB RIN RIT RIT1 RIT2 ROC1 ROC2 TRK TRKA
SUMOylation of DNA damage response and repair proteins	Aladin Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Centrin-2 Chromobox protein homolog 2 Chromobox protein homolog 8 Cohesin subunit SA-1 Cohesin subunit SA-2 DNA repair protein RAD52 homolog DNA repair protein XRCC4 DNA repair protein complementing XP-C cells Double-strand-break repair protein rad21 homolog E3 SUMO-protein ligase CBX4 E3 SUMO-protein ligase NSE2 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 E3 ubiquitin-protein ligase RNF168 EP300-interacting inhibitor of differentiation 3 G/T mismatch-specific thymine DNA glycosylase Histone deacetylase 7 Mediator of DNA damage checkpoint protein 1 Non-structural maintenance of chromosomes element 1 homolog Non-structural maintenance of chromosomes element 3 homolog Non-structural maintenance of chromosomes element 4 homolog A Nuclear autoantigen Sp-100 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Poly [ADP-ribose] polymerase 1 Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Protein PML Protein SEC13 homolog RecQ-like DNA helicase BLM Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Structural maintenance of chromosomes protein 5 Structural maintenance of chromosomes protein 6 Tumor suppressor ARF mRNA export factor RAE1	A8CG34 O00257 O15504 O60216 O75694 O75925 O95714 P09874 P12270 P23497 P27694 P29590 P35226 P35227 P35658 P37198 P38398 P41208 P43351 P49790 P49792 P54132 P55735 P55854 P57740 P61956 P63165 P63279 P78364 P78406 Q01831 Q06587 Q12769 Q13426 Q13569 Q14191 Q14676 Q14683 Q14781 Q5SRE5 Q7Z3B4 Q8IXK0 Q8IY18 Q8IYW5 Q8N140 Q8N1F7 Q8N2W9 Q8N3U4 Q8N726 Q8NDX5 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUI4 Q8WUM0 Q8WV22 Q8WVM7 Q92621 Q96HA1 Q96MF7 Q96MG7 Q96SB8 Q99496 Q99567 Q9BTX1 Q9BW27 Q9HC52 Q9NRG9 Q9NXX6 Q9UKX7 Q9UQE7	AAAS ADPRT ADRACALA BAM BAP1 BLM BMH BMI1 BRCA1 C10orf86 C7orf14 C8orf36 CAIN CALT CAN CBX2 CBX4 CBX8 CDKN2 CDKN2A CEN2 CETN2 CG1 CSPG6 D3S1231E DDXBP1 DING DXS423E EDR1 EDR2 EDR3 EID3 HCA4 HDAC7 HDAC7A HERC2 HIPI3 HR21 KIAA0023 KIAA0078 KIAA0095 KIAA0169 KIAA0170 KIAA0178 KIAA0197 KIAA0225 KIAA0594 KIAA0618 KIAA0791 KIAA0906 MAGEG1 MDC1 MEL18 MLM MMS21 MP44 MRNP41 MYL NDC1 NDNL2 NFBD1 NPAP60L NSMCE1 NSMCE2 NSMCE3 NSMCE4A NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 NXP1 PARP1 PC3 PCGF2 PCGF4 PCNT1 PH1 PH2 PH3 PHC1 PHC2 PHC3 PIAS1 PIAS4 PIASG PML POM121 POM121A POM121C PP8675 PPOL RAD21 RAD52 RAE1 RANBP2 RC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 RING1 RING1A RING1B RNF1 RNF110 RNF168 RNF2 RNF51 RNF53 RNF71 RPA1 RPA70 SA1 SA2 SB1.8 SCC1 SCC3 SEC13 SEC13A SEC13L1 SEC13R SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SMC5 SMC5L1 SMC6 SMC6L1 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SP100 STAG1 STAG2 SUMO1 SUMO2 SUMO3 TDG TMEM48 TPR TRIM19 UBC9 UBCE9 UBE2I UBL1 WRN XPC XPCC XRCC4 ZNF144
Signaling by EGFR	Amphiregulin Angio-associated migratory cell protein Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 12 Disintegrin and metalloproteinase domain-containing protein 17 Epidermal growth factor receptor Epigen Leucine-rich repeats and immunoglobulin-like domains protein 1 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein FAM83A Protein FAM83B Protein FAM83D Protransforming growth factor alpha	O14672 O14944 O43184 P00533 P01133 P01135 P15514 P35070 P78536 Q13685 Q5T0W9 Q6UW88 Q86UY5 Q96JA1 Q99075 Q9H4H8	AAMP ADAM10 ADAM12 ADAM17 AREG AREGB BTC C20orf129 C6orf143 CSVP DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG FAM83A FAM83B FAM83D HBEGF HEGFL HER1 KUZ LIG1 LRIG1 MADM MLTN SDGF TACE TGFA TSGP

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