Formation of apoptosome
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- APAF1
- APIP
- AVEN
- CARD8
- CASP9
- CYC
- CYCS
- DACAR
- KIAA0413
- KIAA0955
- MCH6
- NDPP1
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Activation of caspases through apoptosome-mediated cleavage
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- APAF1
- API3
- BIRC4
- CASP3
- CASP7
- CASP9
- CPP32
- CYC
- CYCS
- IAP3
- KIAA0413
- MCH3
- MCH6
- XIAP
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SMAC (DIABLO) binds to IAPs
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- APAF1
- API3
- BIRC4
- CASP3
- CASP7
- CASP9
- CPP32
- CYC
- CYCS
- DIABLO
- IAP3
- KIAA0413
- MCH3
- MCH6
- SMAC
- XIAP
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SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
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- APAF1
- API3
- BIRC4
- CASP3
- CASP7
- CASP9
- CPP32
- CYC
- CYCS
- DIABLO
- IAP3
- KIAA0413
- MCH3
- MCH6
- SMAC
- XIAP
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Regulation of the apoptosome activity
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- APAF1
- API3
- APIP
- AVEN
- BIRC4
- CARD8
- CASP9
- CYC
- CYCS
- DACAR
- DIABLO
- ERK1
- ERK2
- IAP3
- KIAA0413
- KIAA0955
- KIAA1561
- MAPK1
- MAPK3
- MCH6
- NDPP1
- PRKM1
- PRKM2
- PRKM3
- SMAC
- UACA
- XIAP
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Activation of the TFAP2 (AP-2) family of transcription factors
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- AP2TF
- CBP
- CITED1
- CITED2
- CITED4
- CREBBP
- EP300
- FOR
- GAS41
- MRG1
- MRG2
- MSG1
- P300
- SDR41C1
- TFAP2
- TFAP2A
- TFAP2B
- TFAP2BL1
- TFAP2C
- TFAP2D
- TFAP2E
- WOX1
- WWOX
- YEATS4
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Negative regulation of activity of TFAP2 (AP-2) family transcription factors
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- AP2TF
- C18orf5
- FOR
- KCTD1
- KCTD15
- SDR41C1
- SMT3C
- SMT3H3
- SUMO1
- TFAP2
- TFAP2A
- TFAP2B
- TFAP2BL1
- TFAP2C
- TFAP2D
- TFAP2E
- UBC9
- UBCE9
- UBE2I
- UBL1
- WOX1
- WWOX
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TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
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- AP2TF
- BMYB
- HSP60
- HSPD1
- MYBL2
- NOL1
- NOP2
- NPM
- NPM1
- NSUN1
- TFAP2
- TFAP2A
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Specification of the neural plate border
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- AP2TF
- BMP2B
- BMP4
- CTNNB
- CTNNB1
- DLX5
- DVR4
- FGF4
- GBX2
- HOX7
- HST
- HSTF1
- HUP1
- HUP2
- KS3
- MSX1
- MYB
- OCT3
- OCT4
- OTF3
- PAX3
- PAX7
- POU5F1
- SOX2
- TCF3
- TCF7L1
- TFAP2
- TFAP2A
- TFAP2B
- TFAP2C
- WNT3A
- ZIC
- ZIC1
- ZNF201
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TFAP2 (AP-2) family regulates transcription of cell cycle factors
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- AP2TF
- BHLHE39
- CAP20
- CDKN1
- CDKN1A
- CIP1
- JARID1B
- KDM5B
- MDA6
- MYC
- PIC1
- PLU1
- RBBP2H1
- SDI1
- TFAP2
- TFAP2A
- TFAP2C
- WAF1
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TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
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- AP2TF
- ATAD2
- CGA
- CGB
- CGB3
- CGB5
- CGB8
- EGFR
- ERBB
- ERBB1
- ERBB2
- ESR
- ESR1
- HER1
- HER2
- INO80S
- KIT
- MLN19
- NEU
- NGL
- NR3A1
- SCFR
- TFAP2
- TFAP2A
- TFAP2B
- TFAP2C
- TGFA
- VEGF
- VEGFA
- YY1
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TFAP2 (AP-2) family regulates transcription of other transcription factors
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- AP2TF
- ARP1
- CITED2
- MRG1
- PITX2
- RGS
- RIEG
- RIEG1
- TFAP2
- TFAP2A
- TFAP2C
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Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
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- AP2TF
- APOE
- DEK
- TFAP2
- TFAP2A
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Formation of annular gap junctions
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- AP2M1
- CLAPM1
- CLH17
- CLH22
- CLTA
- CLTB
- CLTC
- CLTCL
- CLTCL1
- CLTCL2
- CLTD
- DAB2
- DNM
- DNM1
- DNM2
- DOC2
- DYN2
- GJA1
- GJAL
- KIAA0034
- KIAA0109
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Gap junction degradation
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- AP2M1
- CLAPM1
- CLH17
- CLH22
- CLTA
- CLTB
- CLTC
- CLTCL
- CLTCL1
- CLTCL2
- CLTD
- DAB2
- DNM
- DNM1
- DNM2
- DOC2
- DYN2
- GJA1
- GJAL
- KIAA0034
- KIAA0109
- KIAA0389
- MYO6
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Nef mediated downregulation of CD28 cell surface expression
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- AP2M1
- CD28
- CLAPM1
- KIAA0109
- nef
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SUMO is conjugated to E1 (UBA2:SAE1)
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- AOS1
- SAE1
- SAE2
- SMT3A
- SMT3B
- SMT3C
- SMT3H1
- SMT3H2
- SMT3H3
- SUA1
- SUMO1
- SUMO2
- SUMO3
- UBA2
- UBL1
- UBLE1A
- UBLE1B
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SUMO is transferred from E1 to E2 (UBE2I, UBC9)
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- AOS1
- RSUME
- RWDD3
- SAE1
- SAE2
- SMT3A
- SMT3B
- SMT3C
- SMT3H1
- SMT3H2
- SMT3H3
- SUA1
- SUMO1
- SUMO2
- SUMO3
- UBA2
- UBC9
- UBCE9
- UBE2I
- UBL1
- UBLE1A
- UBLE1B
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Detoxification of Reactive Oxygen Species
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- AOP1
- AOP2
- APAH1
- AQP8
- ATOX1
- ATP7A
- CAT
- CCS
- CYBA
- CYBB
- CYC
- CYCS
- ERBA2L
- ERO1A
- ERO1L
- FAEES3
- GPX1
- GPX2
- GPX3
- GPX5
- GPX6
- GPX7
- GPX8
- GPXP
- GRIM12
- GST3
- GSTP1
- HAH1
- KDRF
- KIAA0106
- KIAA1652
- MC1
- MNK
- NCF1
- NCF2
- NCF4
- NKEFB
- NOX2
- NOX4
- NOX5
- NOXA2
- NOXO2
- NUDT2
- P4HB
- P67PHOX
- PAGA
- PAGB
- PDI
- PDIA1
- PO4DB
- PRDX1
- PRDX2
- PRDX3
- PRDX6
- RENOX
- SH3PXD1A
- SH3PXD4
- SOD1
- SOD2
- SOD3
- TDPX1
- TDPX2
- TRDX
- TRX
- TRX1
- TRX2
- TRXR2
- TXN
- TXN2
- TXNRD1
- TXNRD2
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Regulation of PTEN gene transcription
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- AOF2
- ATF2
- ATN1
- BAP1
- BMI1
- C11orf59
- C7orf59
- CBX2
- CBX4
- CBX6
- CBX8
- CHD3
- CHD4
- CHET9
- CREB2
- CREBP1
- D12S755E
- DING
- DRPLA
- EDR1
- EDR2
- EDR3
- EED
- EGR1
- ERK1
- ERK2
- EVI1
- EZH2
- FRAP
- FRAP1
- FRAP2
- GATAD2A
- GATAD2B
- GBL
- HBXIP
- HDAC1
- HDAC2
- HDAC3
- HDAC5
- HDAC7
- HDAC7A
- HIPI3
- JJAZ1
- JUN
- KDM1
- KDM1A
- KIAA0071
- KIAA0160
- KIAA0600
- KIAA0601
- KIAA1150
- KIAA1266
- KIAA1303
- KMT6
- KROX24
- LAMTOR1
- LAMTOR2
- LAMTOR3
- LAMTOR4
- LAMTOR5
- LSD1
- LST8
- MAF1
- MAP2K1IP1
- MAPBPIP
- MAPK1
- MAPK3
- MAPKSP1
- MBD3
- MDS1
- MECOM
- MLST8
- MTA1
- MTA1L1
- MTA2
- MTA3
- MTOR
- NR1C3
- NR2E1
- NRSF
- P53
- PC3
- PCGF4
- PDRO
- PH1
- PH2
- PH3
- PHC1
- PHC2
- PHC3
- PID
- PPARG
- PRDM3
- PRKM1
- PRKM2
- PRKM3
- RAFT1
- RAPT1
- RAPTOR
- RBAP46
- RBAP48
- RBBP4
- RBBP7
- RC1
- RCOR
- RCOR1
- REST
- RHEB
- RHEB2
- RING1
- RING1A
- RING1B
- RNF1
- RNF2
- RNF51
- ROBLD3
- RPD3L1
- RPTOR
- RRAGA
- RRAGB
- RRAGC
- RRAGD
- SALL4
- SLC38A9
- SLUG
- SLUGH
- SNAH
- SNAI1
- SNAI2
- SUZ12
- TLX
- TP53
- URLC11
- XBR
- XIP
- ZNF225
- ZNF797
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HDACs deacetylate histones
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- AOF2
- ARID4A
- ARID4B
- BHC80
- BRAF35
- BRCAA1
- BRMS1
- CHD3
- CHD4
- CTG26
- GATAD2A
- GATAD2B
- GPS2
- H2AC1
- H2AC11
- H2AC12
- H2AC13
- H2AC14
- H2AC15
- H2AC16
- H2AC17
- H2AC18
- H2AC19
- H2AC20
- H2AC21
- H2AC25
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFC
- H2AFD
- H2AFE
- H2AFG
- H2AFI
- H2AFL
- H2AFM
- H2AFN
- H2AFO
- H2AFP
- H2AFQ
- H2AFR
- H2AW
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC18
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFT
- H2BU1
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HDAC1
- HDAC10
- HDAC2
- HDAC3
- HDAC8
- HDACL1
- HIRIP1
- HIRIP2
- HIST1H2AA
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AG
- HIST1H2AH
- HIST1H2AI
- HIST1H2AJ
- HIST1H2AK
- HIST1H2AL
- HIST1H2AM
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AB
- HIST2H2AC
- HIST2H2BE
- HIST2H2BF
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2A
- HIST3H2BB
- HIST4H4
- HMG20B
- HMGX2
- HMGXB2
- IRA1
- KDM1
- KDM1A
- KIAA0071
- KIAA0601
- KIAA1047
- KIAA1150
- KIAA1266
- KIAA1696
- LSD1
- MBD3
- MTA1
- MTA1L1
- MTA2
- MTA3
- NCOR1
- NCOR2
- NRSF
- NS4ATP2
- PHF21A
- PID
- RBAP46
- RBAP48
- RBBP1
- RBBP1L1
- RBBP4
- RBBP7
- RBP1
- RBP1L1
- RCOR
- RCOR1
- REST
- RPD3L1
- SAP18
- SAP180
- SAP30
- SAP30L
- SAP45
- SDS3
- SMARCE1R
- SUDS3
- TBL1
- TBL1X
- TBL1XR1
- TBLR1
- TSH2B
- XBR
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|
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
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|
|
- AOF2
- APS
- AR
- BHLHE75
- DHTR
- GASC1
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST4H4
- JHDM3C
- JMJD2C
- KDM1
- KDM1A
- KDM4C
- KIAA0601
- KIAA0780
- KLK2
- KLK3
- LSD1
- NCOA2
- NR3C4
- PAK1
- PKN
- PKN1
- PRK1
- PRKCL1
- SRC2
- TIF2
- TSH2B
|
|
HDMs demethylate histones
|
|
|
- AOF1
- AOF2
- ARID5B
- C5orf7
- C6orf193
- CENP-35
- CXXC2
- CXXC8
- DESRT
- DXS1272E
- FBL10
- FBL11
- FBL7
- FBXL10
- FBXL11
- GASC1
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST4H4
- HY
- HYA
- JARID1A
- JARID1B
- JARID1C
- JARID1D
- JHDM1A
- JHDM1B
- JHDM1D
- JHDM2A
- JHDM2B
- JHDM3A
- JHDM3B
- JHDM3C
- JHDM3D
- JMJD1
- JMJD1A
- JMJD1B
- JMJD2
- JMJD2A
- JMJD2B
- JMJD2C
- JMJD2D
- JMJD3
- JMJD6
- KDM1
- KDM1A
- KDM1B
- KDM2A
- KDM2B
- KDM3A
- KDM3B
- KDM4A
- KDM4B
- KDM4C
- KDM4D
- KDM5A
- KDM5B
- KDM5C
- KDM5D
- KDM6A
- KDM6B
- KDM6C
- KDM7
- KDM7A
- KIAA0234
- KIAA0346
- KIAA0585
- KIAA0601
- KIAA0662
- KIAA0677
- KIAA0742
- KIAA0780
- KIAA0876
- KIAA1004
- KIAA1082
- KIAA1111
- KIAA1718
- LSD1
- LSD2
- MDIG
- MINA
- MINA53
- MRF2
- NDY1
- NO52
- PCCX2
- PHF2
- PHF8
- PLU1
- PSR
- PTDSR
- RBBP2
- RBBP2H1
- RBP2
- RIOX2
- SMCX
- SMCY
- TSGA
- UTX
- UTY
- XE169
- ZNF422
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Vitamin B6 activation to pyridoxal phosphate
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- AO
- AOX1
- C21orf124
- C21orf97
- PDXK
- PKH
- PNK
- PNPO
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HuR (ELAVL1) binds and stabilizes mRNA
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- ANP32A
- APRIL
- C15orf1
- CAIN
- CAN
- CRM1
- ELAVL1
- HUR
- KIAA0023
- LANP
- MAPM
- NUP214
- PHAP1
- PKCA
- PKCD
- PRKACA
- PRKCA
- PRKCD
- SET
- TALL2
- TNFSF13
- XPO1
- ZTNF2
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