GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **876 - 900** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol
Kinesins	Centromere-associated protein E Chromosome-associated kinesin KIF4A Chromosome-associated kinesin KIF4B Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 2 Kinesin light chain 3 Kinesin light chain 4 Kinesin-1 heavy chain Kinesin-associated protein 3 Kinesin-like protein (Fragment) Kinesin-like protein (Fragment) Kinesin-like protein KIF11 Kinesin-like protein KIF12 Kinesin-like protein KIF13B Kinesin-like protein KIF15 Kinesin-like protein KIF16B Kinesin-like protein KIF18A Kinesin-like protein KIF18B Kinesin-like protein KIF19 Kinesin-like protein KIF1A Kinesin-like protein KIF1B Kinesin-like protein KIF1C Kinesin-like protein KIF20A Kinesin-like protein KIF20B Kinesin-like protein KIF21A Kinesin-like protein KIF21B Kinesin-like protein KIF22 Kinesin-like protein KIF23 Kinesin-like protein KIF25 Kinesin-like protein KIF26A Kinesin-like protein KIF26B Kinesin-like protein KIF27 Kinesin-like protein KIF28P Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinesin-like protein KIF3A Kinesin-like protein KIF3B Kinesin-like protein KIF3C Kinesin-like protein KIF6 Kinesin-like protein KIF9 Kinesin-like protein KIFC1 Kinesin-like protein KIFC2 Rac GTPase-activating protein 1	B7ZC32 O00139 O14782 O15066 O43896 O60333 O75037 O95235 O95239 P33176 P52732 Q02224 Q02241 Q07866 Q12756 Q12840 Q14807 Q2KJY2 Q2TAC6 Q2VIQ3 Q66K46 Q6P597 Q6PKD1 Q6ZMV9 Q7Z4S6 Q86VH2 Q86Y91 Q8N4N8 Q8NI77 Q92845 Q96AC6 Q96FN5 Q96L93 Q96Q89 Q99661 Q9BW19 Q9H0B6 Q9H0H5 Q9HAQ2 Q9NQT8 Q9NS87 Q9NSK0 Q9UIL4 Q9ULI4 Q9Y496	ATSV C20orf23 C2orf20 C6orf102 CENPE EG5 GAKIN HSET KIAA0359 KIAA0449 KIAA0591 KIAA0639 KIAA0706 KIAA1236 KIAA1448 KIAA1478 KIAA1590 KIAA1708 KID KIF11 KIF12 KIF13B KIF15 KIF16B KIF18A KIF18B KIF19 KIF1A KIF1B KIF1C KIF2 KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF25 KIF26A KIF26B KIF27 KIF28P KIF2A KIF2B KIF2C KIF3 KIF3A KIF3AP KIF3B KIF3C KIF4 KIF4A KIF4B KIF5A KIF5B KIF5C KIF6 KIF9 KIFAP3 KIFC1 KIFC2 KLC KLC1 KLC2 KLC2L KLC3 KLC4 KLP2 KLP6 KNS KNS1 KNS2 KNSL1 KNSL2 KNSL3 KNSL4 KNSL5 KNSL6 KNSL7 KNSL8 KRMP1 MGCRACGAP MKLP1 MKLP2 MPHOSPH1 NKHC1 RAB6KIFL RACGAP1 SMAP SNX23 TRIP5
Polo-like kinase mediated events	Centromere protein F Forkhead box protein M1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Histone acetyltransferase p300 Histone-binding protein RBBP4 M-phase inducer phosphatase 1 M-phase inducer phosphatase 3 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Myb-related protein B Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Serine/threonine-protein kinase PLK1 Wee1-like protein kinase	O95067 P10244 P14635 P30291 P30304 P30307 P49454 P53350 Q08050 Q09028 Q09472 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99640	BARA BMYB C14orf46 CCNB CCNB1 CCNB2 CDC25A CDC25C CENPF CXCDC1 EP300 FKHL16 FOXM1 HFH11 KIAA2037 LIN37 LIN52 LIN54 LIN9 MPP2 MYBL2 MYT1 P300 PKMYT1 PLK PLK1 RBAP48 RBBP4 TGS WEE1 WIN
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein C Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere protein W Centromere protein X Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3-like centromeric protein A Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Holliday junction recognition protein Kinetochore scaffold 1 Mis18-binding protein 1 Nucleophosmin Protein Mis18-alpha Protein Mis18-beta Remodeling and spacing factor 1 RuvB-like 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	A8MT69 O43482 O60264 O60814 P04908 P06748 P06899 P0C5Y9 P16104 P20671 P23527 P33778 P49450 P57053 P58876 P62805 P62807 Q03188 Q09028 Q13352 Q16576 Q16777 Q16778 Q5EE01 Q6FI13 Q6IPU0 Q6P0N0 Q71F23 Q71UI9 Q7L2Z9 Q8N0S6 Q8N257 Q8N2Z9 Q8NCD3 Q8NG31 Q92674 Q93077 Q93079 Q96A08 Q96BT3 Q96H22 Q96T23 Q99877 Q99878 Q99879 Q99880 Q9BS16 Q9BTM1 Q9BU64 Q9H3R5 Q9NSP4 Q9NYP9 Q9Y265	APITD1 C14orf106 C16orf56 C16orf60 C1orf155 C21orf45 C21orf46 C22orf18 C6orf139 C6orf173 CASC5 CENPA CENPC CENPC1 CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CENPW CENPX CUG2 FAAP10 FAAP16 FAKTS FASP1 FLEG1 FSHPRH1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HBXAP HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HJURP ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INO80H ITGB3BP KIAA1570 KIAA1903 KLIP1 KNL1 KNL2 LRPR1 M18BP1 MCM21R MHF1 MHF2 MIS18A MIS18B MIS18BP1 MLF1IP NMP238 NPM NPM1 NRIF3 OIP5 PANE1 PBIP1 RBAP46 RBAP48 RBBP4 RBBP7 RSF1 RUVBL1 SMARCA5 SNF2H STRA13 TIP49 TIP49A TSH2B URLC9 WCRF135 XAP8
Loss of function of TP53 in cancer due to loss of tetramerization ability	Cellular tumor antigen p53	P04637	P53 TP53
Activation of NOXA and translocation to mitochondria	Cellular tumor antigen p53 Phorbol-12-myristate-13-acetate-induced protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1	P04637 Q01094 Q13794 Q14186 Q14188	DP1 DP2 E2F1 NOXA P53 PMAIP1 RBBP3 TFDP1 TFDP2 TP53
Regulation of TP53 Expression	Cellular tumor antigen p53 PR domain zinc finger protein 1	O75626 P04637	BLIMP1 P53 PRDM1 TP53
Stabilization of p53	Cellular tumor antigen p53 E3 ubiquitin-protein ligase Mdm2 PHD finger protein 20 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Serine-protein kinase ATM Serine/threonine-protein kinase Chk2 Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15151 O96017 P04637 P0CG47 P0CG48 P62979 P62987 Q00987 Q13315 Q8N726 Q9BVI0	ATM C20orf104 CDKN2 CDKN2A CDS1 CHEK2 CHK2 GLEA2 HCA58 MDM2 MDM4 MDMX MLM NZF P53 PHF20 RAD53 RPS27A TP53 TZP UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Regulation of TP53 Activity through Methylation	Cellular tumor antigen p53 E3 ubiquitin-protein ligase Mdm2 Histone acetyltransferase p300 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Junction-mediating and -regulatory protein Lethal(3)malignant brain tumor-like protein 1 N-lysine methyltransferase KMT5A N-lysine methyltransferase SMYD2 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Protein arginine N-methyltransferase 5 SET domain-containing protein 9 Serine-protein kinase ATM Serine/threonine-protein kinase Chk2 Tetratricopeptide repeat protein 5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14744 O15151 O96017 P04637 P0CG47 P0CG48 P62979 P62987 Q00987 Q09472 Q13315 Q8N0Z6 Q8N9B5 Q8NE22 Q96KQ7 Q9H9B1 Q9NQR1 Q9NRG4 Q9Y468	ATM BAT8 C5orf35 C6orf30 CDS1 CHEK2 CHK2 EHMT1 EHMT2 EP300 EUHMTASE1 G9A GLP HRMT1L5 IBP72 JBP1 JMY KIAA0681 KIAA1876 KMT1C KMT1D KMT3C KMT5A L3MBT L3MBTL L3MBTL1 MDM2 MDM4 MDMX NG36 P300 P53 PRMT5 PRSET7 RAD53 RPS27A SET07 SET8 SETD8 SETD9 SKB1 SMYD2 TP53 TTC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
SUMOylation of transcription factors	Cellular tumor antigen p53 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase Mdm2 Forkhead box protein L2 Hypermethylated in cancer 1 protein Metastasis-associated protein MTA1 Microphthalmia-associated transcription factor SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 TP53-binding protein 1 Transcription factor AP-2 gamma Transcription factor AP-2-beta Transcription factor Sp3 Tumor suppressor ARF	O75030 O75925 P04637 P55854 P58012 P61956 P63165 P63279 Q00987 Q02447 Q12888 Q13330 Q14526 Q8N2W9 Q8N726 Q92481 Q92754 Q9Y6X2	BHLHE32 CDKN2 CDKN2A DDXBP1 FOXL2 HIC1 MDM2 MITF MLM MTA1 P53 PIAS1 PIAS3 PIAS4 PIASG SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SP3 SUMO1 SUMO2 SUMO3 TFAP2B TFAP2C TP53 TP53BP1 UBC9 UBCE9 UBE2I UBL1 ZBTB29
PI5P Regulates TP53 Acetylation	Cellular tumor antigen p53 Dual specificity mitogen-activated protein kinase kinase 6 Histone acetyltransferase p300 Inhibitor of growth protein 2 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase	P04637 P48426 P52564 P78356 Q09472 Q13526 Q86T03 Q8TBX8 Q9H160	C14orf9 EP300 ING1L ING2 MAP2K6 MEK6 MKK6 P300 P53 PI5P4KA PIN1 PIP4K2A PIP4K2B PIP4K2C PIP4P1 PIP5K2 PIP5K2A PIP5K2B PIP5K2C PRKMK6 SKK3 TMEM55B TP53
Transcriptional activation of cell cycle inhibitor p21	Cellular tumor antigen p53 Cyclin-dependent kinase inhibitor 1 Poly(rC)-binding protein 4 Zinc finger protein 385A	P04637 P38936 P57723 Q96PM9	CAP20 CDKN1 CDKN1A CIP1 HZF MDA6 P53 PCBP4 PIC1 RZF SDI1 TP53 WAF1 ZNF385 ZNF385A
RUNX3 regulates CDKN1A transcription	Cellular tumor antigen p53 Cyclin-dependent kinase inhibitor 1 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein Zinc finger homeobox protein 3	P01137 P04637 P38936 P84022 Q13485 Q13761 Q15911	AML2 ATBF1 C16orf47 CAP20 CBFA3 CDKN1 CDKN1A CIP1 DPC4 MADH3 MADH4 MDA6 P53 PEBP2A3 PIC1 RUNX3 SDI1 SMAD3 SMAD4 TGFB TGFB1 TP53 WAF1 ZFHX3
Oncogene Induced Senescence	Cellular tumor antigen p53 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A DNA-binding protein inhibitor ID-1 E3 ubiquitin-protein ligase Mdm2 ETS domain-containing transcription factor ERF Helicase MOV-10 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Protein C-ets-1 Protein C-ets-2 Protein Mdm4 Protein argonaute-1 Protein argonaute-3 Protein argonaute-4 Retinoblastoma-associated protein Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3 Transcription factor Sp1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00716 O15151 P04637 P06400 P08047 P0CG47 P0CG48 P11802 P14921 P15036 P27361 P28482 P41134 P42771 P42772 P42773 P50548 P55273 P62979 P62987 Q00534 Q00987 Q01094 Q14186 Q14188 Q14209 Q8N726 Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UL18 Q9UPQ9	AGO1 AGO3 AGO4 BHLHB24 CAGH26 CDK4 CDK6 CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 DP1 DP2 E2F1 E2F2 E2F3 EIF2C1 EIF2C3 EIF2C4 ERF ERK1 ERK2 ETS1 ETS2 EWSR2 ID ID1 KIAA0075 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MAPK1 MAPK3 MDM2 MDM4 MDMX MLM MOV10 MTS1 MTS2 P53 PRKM1 PRKM2 PRKM3 RB1 RBBP3 RPS27A SP1 TFDP1 TFDP2 TNRC6 TNRC6A TNRC6B TNRC6C TP53 TSFP1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Oxidative Stress Induced Senescence	Cellular tumor antigen p53 Chromobox protein homolog 2 Chromobox protein homolog 6 Chromobox protein homolog 8 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 2A Dual specificity mitogen-activated protein kinase kinase 3 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 6 Dual specificity mitogen-activated protein kinase kinase 7 E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Helicase MOV-10 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Interferon beta Lysine-specific demethylase 6B MAP kinase-activated protein kinase 2 MAP kinase-activated protein kinase 3 MAP kinase-activated protein kinase 5 Misshapen-like kinase 1 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Mitogen-activated protein kinase kinase kinase 5 Mitogen-activated protein kinase kinase kinase kinase 4 Polycomb complex protein BMI-1 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Protein argonaute-1 Protein argonaute-3 Protein argonaute-4 Protein c-Fos TRAF2 and NCK-interacting protein kinase Thioredoxin Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3 Transcription factor Jun Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tumor suppressor ARF Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00257 O00716 O14733 O15054 O15151 O60814 O75530 O95503 O95819 P01100 P01574 P04637 P04908 P05412 P06899 P0C5Y9 P0CG47 P0CG48 P10599 P11802 P16104 P20671 P23527 P27361 P28482 P33778 P35226 P42771 P42772 P42773 P45983 P45984 P45985 P46734 P49137 P52564 P53779 P55273 P57053 P58876 P62805 P62807 P62979 P62987 P68431 P78364 P84243 Q00534 Q00987 Q01094 Q06587 Q09028 Q14186 Q14188 Q14209 Q14781 Q15022 Q15759 Q15910 Q16539 Q16576 Q16644 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8IW41 Q8IXK0 Q8N257 Q8N4C8 Q8N726 Q8NDV7 Q8NDX5 Q93077 Q93079 Q96A08 Q99496 Q99683 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H9G7 Q9HC52 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKE5 Q9UL18 Q9UPQ9	AGO1 AGO3 AGO4 ASK1 B55 BAP1 BMI1 CAGH26 CBX2 CBX4 CBX6 CBX8 CDK4 CDK6 CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 CHET9 CSBP CSBP1 CSBP2 CSPB1 DING DP1 DP2 E2F1 E2F2 E2F3 EDR1 EDR2 EDR3 EED EIF2C1 EIF2C3 EIF2C4 ERK1 ERK2 EZH2 FOS G0S7 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HGK HIPI3 HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 IFB IFNB IFNB1 JJAZ1 JMJD3 JNK1 JNK2 JNK3 JNK3A JNKK1 JNKK2 JUN KDM6B KIAA0075 KIAA0160 KIAA0346 KIAA0551 KIAA0687 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KMT6 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAP3K5 MAP4K4 MAP4K6 MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MAPKAPK2 MAPKAPK3 MAPKAPK5 MAPKKK5 MDM2 MDM4 MDMX MEK3 MEK4 MEK6 MEK7 MEKK5 MINK MINK1 MKK3 MKK4 MKK6 MKK7 MLM MOV10 MTS1 MTS2 MXI2 NIK P53 PC3 PCGF4 PH1 PH2 PH3 PHC1 PHC2 PHC3 PRAK PRKM1 PRKM10 PRKM11 PRKM2 PRKM3 PRKM8 PRKM9 PRKMK3 PRKMK4 PRKMK6 PRKMK7 RBAP46 RBAP48 RBBP3 RBBP4 RBBP7 RC1 RING1 RING1A RING1B RNF1 RNF2 RNF51 RPS27A SAPK1 SAPK1A SAPK1B SAPK1C SAPK2 SAPK2A SAPK2B SEK1 SERK1 SKK1 SKK2 SKK3 SKK4 SUZ12 TFDP1 TFDP2 TNIK TNRC6 TNRC6A TNRC6B TNRC6C TP53 TRDX TRX TRX1 TSH2B TXN UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YSK2 ZC3
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	Cell division cycle protein 20 homolog Mitotic spindle assembly checkpoint protein MAD2A	Q12834 Q13257	CDC20 MAD2 MAD2L1
Phosphorylation of Emi1	Cell division cycle protein 20 homolog Cyclin-dependent kinase 1 F-box only protein 5 Fizzy-related protein homolog G2/mitotic-specific cyclin-B1 Serine/threonine-protein kinase PLK1	P06493 P14635 P53350 Q12834 Q9UKT4 Q9UM11	CCNB CCNB1 CDC2 CDC20 CDC28A CDH1 CDK1 CDKN1 EMI1 FBX5 FBXO5 FYR FZR FZR1 KIAA1242 P34CDC2 PLK PLK1
Transcription of E2F targets under negative control by DREAM complex	Cell division control protein 6 homolog DNA topoisomerase 2-alpha Histone deacetylase 1 Histone-binding protein RBBP4 M-phase inducer phosphatase 1 Myc proto-oncogene protein Proliferating cell nuclear antigen Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Protein max Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5	P01106 P11388 P12004 P28749 P30304 P61244 Q01094 Q08999 Q09028 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99741	BARA BHLHD4 BHLHE39 C14orf46 CDC18L CDC25A CDC6 CXCDC1 DP1 DP2 E2F1 E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MAX MYC PCNA RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS TOP2 TOP2A
CDC6 association with the ORC:origin complex	Cell division control protein 6 homolog DNA helicase MCM8 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6	O43913 O43929 Q13415 Q13416 Q99741 Q9UBD5 Q9UJA3 Q9Y5N6	C20orf154 CDC18L CDC6 LATHEO MCM8 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1
Unwinding of DNA	Cell division control protein 45 homolog DNA helicase MCM8 DNA replication complex GINS protein PSF1 DNA replication complex GINS protein PSF2 DNA replication complex GINS protein PSF3 DNA replication complex GINS protein SLD5 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7	O75419 P25205 P33991 P33992 P33993 P49736 Q14566 Q14691 Q9BRT9 Q9BRX5 Q9UJA3 Q9Y248	BM28 C20orf154 CCNL1 CDC21 CDC45 CDC45L CDC45L2 CDC46 CDC47 CDCL1 GINS1 GINS2 GINS3 GINS4 KIAA0030 KIAA0186 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 PSF1 PSF2 PSF3 SLD5
G1/S-Specific Transcription	Cell division control protein 45 homolog Cell division control protein 6 homolog Cyclin-A1 Cyclin-dependent kinase 1 DNA polymerase alpha catalytic subunit DNA replication factor Cdt1 Dihydrofolate reductase F-box only protein 5 G1/S-specific cyclin-E1 Histone deacetylase 1 Histone-binding protein RBBP4 Origin recognition complex subunit 1 Proliferating cell nuclear antigen Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Ribonucleoside-diphosphate reductase subunit M2 Thymidine kinase, cytosolic Thymidylate synthase Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5 Transcription factor E2F6	O75419 O75461 P00374 P04183 P04818 P06493 P09884 P12004 P24864 P28749 P31350 P78396 Q01094 Q08999 Q09028 Q13415 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99741 Q9H211 Q9UKT4	BARA C14orf46 CCNA1 CCNE CCNE1 CDC18L CDC2 CDC28A CDC45 CDC45L CDC45L2 CDC6 CDK1 CDKN1 CDT1 CXCDC1 DHFR DP1 DP2 E2F1 E2F4 E2F5 E2F6 EMI1 FBX5 FBXO5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 ORC1 ORC1L P34CDC2 PARC1 PCNA POLA POLA1 RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 RR2 RRM2 TFDP1 TFDP2 TGS TK1 TS TYMS
Activation of the pre-replicative complex	Cell division control protein 45 homolog Cell division control protein 6 homolog Cell division cycle 7-related protein kinase Cyclin-dependent kinase 2 DNA helicase MCM8 DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA primase large subunit DNA primase small subunit DNA replication factor Cdt1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Geminin Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Protein DBF4 homolog A Protein MCM10 homolog Replication protein A 14 kDa subunit Replication protein A 30 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	O00311 O43913 O43929 O75419 O75496 P09884 P15927 P24941 P25205 P27694 P33991 P33992 P33993 P35244 P49642 P49643 P49736 P56282 Q07864 Q13156 Q13415 Q13416 Q14181 Q14566 Q7L590 Q99741 Q9H211 Q9NR33 Q9NRF9 Q9UBD5 Q9UBU7 Q9UJA3 Q9Y5N6	ASK BM28 C20orf154 CCNL1 CDC18L CDC21 CDC45 CDC45L CDC45L2 CDC46 CDC47 CDC6 CDC7 CDC7L1 CDCL1 CDK2 CDKN2 CDT1 CHRAC17 DBF4 DBF4A DPE2 GMNN KIAA0030 LATHEO MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1 POLA POLA1 POLA2 POLE POLE1 POLE2 POLE3 POLE4 PRIM1 PRIM2 PRIM2A REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA4 RPA70 ZDBF1
Inactivation of CDC42 and RAC1	Cell division control protein 42 homolog Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 39 Roundabout homolog 1 SLIT-ROBO Rho GTPase-activating protein 1 SLIT-ROBO Rho GTPase-activating protein 2 SLIT-ROBO Rho GTPase-activating protein 3 Slit homolog 2 protein	O43295 O75044 O94813 P60953 P63000 Q7Z6B7 Q9C0H5 Q9Y6N7	ARHGAP13 ARHGAP14 ARHGAP34 ARHGAP39 CDC42 DUTT1 FNBP2 KIAA0411 KIAA0456 KIAA1156 KIAA1304 KIAA1688 MEGAP RAC1 ROBO1 SLIL3 SLIT2 SRGAP1 SRGAP2 SRGAP2A SRGAP3 TC25
CD28 dependent Vav1 pathway	Cell division control protein 42 homolog Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck	O75914 P06239 P06241 P10747 P15498 P33681 P42081 P60953 P63000 Q13153 Q13177	CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 CDC42 FYN LAB7 LCK OPHN3 PAK1 PAK2 PAK3 RAC1 TC25 VAV VAV1
RHO GTPases activate KTN1	Cell division control protein 42 homolog Kinectin Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 2 Kinesin light chain 3 Kinesin light chain 4 Kinesin-1 heavy chain Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoG Transforming protein RhoA	P33176 P60953 P61586 P63000 P84095 Q07866 Q12840 Q6P597 Q86UP2 Q9H0B6 Q9NSK0	ARH12 ARHA ARHG CDC42 CG1 KIAA0004 KIF5A KIF5B KLC KLC1 KLC2 KLC2L KLC3 KLC4 KNS KNS1 KNS2 KNSL8 KTN1 NKHC1 RAC1 RHO12 RHOA RHOG TC25
G beta:gamma signalling through CDC42	Cell division control protein 42 homolog Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rho guanine nucleotide exchange factor 6 Serine/threonine-protein kinase PAK 1	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P60953 P61952 P62873 P62879 P63211 P63215 P63218 Q13153 Q15052 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ARHGEF6 CDC42 COOL2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0006 PAK1 PIXA

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