AKT phosphorylates targets in the cytosol
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- AKT1
- AKT1S1
- AKT2
- AKT3
- BAD
- BBC6
- BCL2L8
- CAP20
- CASP9
- CDKN1
- CDKN1A
- CDKN1B
- CHUK
- CIP1
- GSK3A
- GSK3B
- IKKA
- KIP1
- MCH6
- MDA6
- MDM2
- MKRN1
- PIC1
- PKB
- PKBG
- PRAS40
- RAC
- RNF61
- SDI1
- TCF16
- TSC2
- TSC4
- WAF1
- p27
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Nuclear events stimulated by ALK signaling in cancer
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- AGO1
- AGO2
- AGO3
- AGO4
- AILIM
- AIM
- APRF
- BCL2A1
- BCL2L5
- BFL1
- BHLHA38
- CCNB
- CCNB1
- CEBPB
- CGL1
- CSPB
- CTLA1
- CUL1
- CXXC9
- DNMT
- DNMT1
- EIF2C1
- EIF2C2
- EIF2C3
- EIF2C4
- EMC19
- ERK1
- ERK2
- FKHL16
- FOXM1
- GRB
- GRS
- GZMB
- HBPA1
- HCP
- HDAC1
- HFH11
- ICOS
- IL10R
- IL10RA
- IRF4
- JUNB
- KIAA1567
- KIAA1582
- KIAA1631
- MAPK1
- MAPK3
- MOV10
- MPP2
- MUM1
- NIPA
- NPM
- NPM1
- OCP2
- PFP
- PRF1
- PRKM1
- PRKM2
- PRKM3
- PTP1C
- PTPN6
- RB1
- RBX1
- RNF75
- ROC1
- RPD3L1
- RPS6
- SKP1
- SKP1A
- SRK
- STAT3
- STAT5
- STAT5A
- TCEB1L
- TCF5
- TNRC6C
- TWIST
- TWIST1
- WIN
- ZAP70
- ZC3HC1
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Activation of BMF and translocation to mitochondria
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- BMF
- DLC2
- DYNLL2
- JNK1
- MAPK8
- PRKM8
- SAPK1
- SAPK1C
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RUNX3 regulates BCL2L11 (BIM) transcription
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- AML2
- BCL2L11
- BIM
- CBFA3
- DPC4
- FKHRL1
- FOXO3
- FOXO3A
- MADH3
- MADH4
- PEBP2A3
- RUNX3
- SMAD3
- SMAD4
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Activation of BIM and translocation to mitochondria
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- BCL2L11
- BIM
- DLC1
- DNCL1
- DNCLC1
- DYNLL1
- HDLC1
- JNK1
- MAPK8
- PRKM8
- SAPK1
- SAPK1C
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FLT3 Signaling
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- AKT1
- AKT2
- AKT3
- BCL2L11
- BIM
- CD135
- CDKN1B
- FKHRL1
- FLK2
- FLT3
- FLT3LG
- FOXO3
- FOXO3A
- GAB2
- GADS
- GRAP2
- GRB1
- GRB10
- GRB2L
- GRBIR
- GRID
- HRAS
- HRAS1
- KIAA0207
- KIAA0571
- KIP1
- NRAS
- PIK3CA
- PIK3R1
- PKB
- PKBG
- PTP2C
- PTPN11
- RAC
- SHPTP2
- SOS1
- STK1
- p27
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SARS-CoV-1-mediated effects on programmed cell death
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- 3a
- 7a
- BCL2L
- BCL2L1
- BCLX
- E
- sM
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STAT5 activation downstream of FLT3 ITD mutants
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- ASH
- BCL2L
- BCL2L1
- BCLX
- CAP20
- CD135
- CDKN1
- CDKN1A
- CIP1
- FLK2
- FLT3
- GAB2
- GRB2
- KIAA0571
- MDA6
- NOX4
- PIC1
- PIM1
- PTP2C
- PTPN11
- RENOX
- SDI1
- SHPTP2
- STAT5
- STAT5A
- STAT5B
- STK1
- WAF1
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Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)
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Proton-coupled monocarboxylate transport
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- BSG
- EMB
- MCT1
- MCT2
- MCT3
- MCT4
- SLC16A1
- SLC16A3
- SLC16A7
- SLC16A8
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Laminin interactions
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- CD49B
- COL18A1
- FNRB
- HSPG2
- ITGA1
- ITGA2
- ITGA3
- ITGA6
- ITGA7
- ITGAV
- ITGB1
- ITGB4
- KIAA0533
- KIAA1907
- LAMA
- LAMA1
- LAMA2
- LAMA3
- LAMA4
- LAMA5
- LAMB1
- LAMB2
- LAMB2T
- LAMB3
- LAMC1
- LAMC2
- LAMC3
- LAMM
- LAMNA
- LAMNB1
- LAMNB2
- LAMS
- MDF2
- MSK12
- MSK18
- MSK8
- NID
- NID1
- NID2
- VNRA
- VTNR
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Integration of viral DNA into host genomic DNA
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- BAF
- BANF1
- BCRG1
- DFS70
- HMGA1
- HMGIY
- LEDGF
- PSIP1
- PSIP2
- gag
- gag-pol
- rev
- vif
- vpr
- vpu
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Autointegration results in viral DNA circles
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- BAF
- BANF1
- BCRG1
- DFS70
- HMGA1
- HMGIY
- LEDGF
- PSIP1
- PSIP2
- gag
- gag-pol
- rev
- vif
- vpr
- vpu
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APOBEC3G mediated resistance to HIV-1 infection
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- BAF
- BANF1
- BCRG1
- CYPA
- DFS70
- HMGA1
- HMGIY
- LEDGF
- PPIA
- PSIP1
- PSIP2
- gag
- gag-pol
- rev
- vif
- vpr
- vpu
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Integration of provirus
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- BAF
- BANF1
- BCRG1
- CYPA
- DFS70
- HMGA1
- HMGIY
- KPNA1
- LEDGF
- PPIA
- PSIP1
- PSIP2
- RCH2
- gag
- gag-pol
- rev
- vif
- vpr
- vpu
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Nuclear Envelope Breakdown
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- BAF
- BANF1
- BCRG1
- EDMD
- EMD
- LEMD2
- LEMD3
- MAN1
- STA
- VRK1
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2-LTR circle formation
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- BAF
- BANF1
- BCRG1
- DFS70
- G22P1
- G22P2
- HMGA1
- HMGIY
- LEDGF
- LIG4
- PSIP1
- PSIP2
- XRCC4
- XRCC5
- XRCC6
- gag
- gag-pol
- rev
- vif
- vpr
- vpu
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Sensory processing of sound by inner hair cells of the cochlea
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- ACZ
- AIE75
- ATP2B1
- BSN
- C20orf145
- C6orf32
- C9orf75
- CABP1
- CABP2
- CACH3
- CACN4
- CACNA1D
- CACNA2D2
- CACNB2
- CACNL1A2
- CACNLB2
- CAPZA1
- CAPZA2
- CAPZB
- CASK
- CCHL1A2
- CDH23
- CIB2
- CLIC5
- CLN4
- CMYA3
- DAL1
- DFNB25
- DFNB31
- DFNB36
- DFNB59
- DIFF48
- DNAJC5
- EPB41L1
- EPB41L3
- EPS8
- EPS8L2
- EPS8R2
- ESPN
- ESPNL
- EZR
- FAM65B
- FER1L2
- FSCN2
- GRXCR1
- GRXCR2
- KCNMA
- KCNMA1
- KCNMB1
- KCNQ4
- KIAA0338
- KIAA0386
- KIAA0434
- KIAA0558
- KIAA0559
- KIAA0987
- KIAA1526
- KIAA1774
- KIAA1812
- KIP2
- LHFPL5
- LIN2
- LRRC52
- MSN
- MYH9
- MYO15
- MYO15A
- MYO1C
- MYO3A
- MYO3B
- MYO7A
- MYSB
- NEAS
- OTOF
- PCDH15
- PCLO
- PJVK
- PL48
- PLS1
- PMCA1
- PTK9
- PTK9L
- RAB3A
- RDX
- RIPOR2
- SANS
- SLC17A8
- SLO
- SNAP
- SNAP25
- SPTA2
- SPTAN1
- SPTB2
- SPTBN1
- STRC
- STX1
- STX1A
- SYB2
- SYN1
- SYP
- TMC1
- TMC2
- TMHS
- TMIE
- TPRN
- TWF1
- TWF2
- USH1B
- USH1C
- USH1F
- USH1G
- VAMP2
- VGLUT3
- VIL2
- WHRN
- XIRP2
- ZNF231
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Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA)
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TICAM1, RIP1-mediated IKK complex recruitment
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- API1
- API2
- BIRC2
- BIRC3
- BLU
- CHUK
- CROC1
- FIP3
- IKBKB
- IKBKG
- IKKA
- IKKB
- MIHB
- MIHC
- NEMO
- PRVTIRB
- PUBC1
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- RNF48
- RNF49
- RNF85
- RPS27A
- SFT
- TCF16
- TICAM1
- TLR3
- TRAF6
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBC5A
- UBC5B
- UBC5C
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5
- UBCH5A
- UBCH5B
- UBCH5C
- UBE2D1
- UBE2D2
- UBE2D3
- UBE2N
- UBE2V
- UBE2V1
- UEV1
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IKK complex recruitment mediated by RIP1
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- API1
- API2
- BIRC2
- BIRC3
- BLU
- CD14
- CHUK
- CROC1
- ESOP1
- FIP3
- IKBKB
- IKBKG
- IKKA
- IKKB
- LY96
- MD2
- MIHB
- MIHC
- NEMO
- PRVTIRB
- PUBC1
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- RNF48
- RNF49
- RNF85
- RPS27A
- SFT
- TCF16
- TICAM1
- TICAM2
- TIRAP3
- TIRP
- TLR4
- TRAF6
- TRAM
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBC5A
- UBC5B
- UBC5C
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5
- UBCH5A
- UBCH5B
- UBCH5C
- UBE2D1
- UBE2D2
- UBE2D3
- UBE2N
- UBE2V
- UBE2V1
- UEV1
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TNFR1-induced NF-kappa-B signaling pathway
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- API1
- API2
- API3
- BIRC2
- BIRC3
- BIRC4
- C20orf18
- CHUK
- CYLD
- CYLD1
- DUBA7
- EBI6
- FIP2
- FIP3
- GLC1E
- GNB2L1
- HIP7
- HYPL
- IAP3
- IKBKB
- IKBKG
- IKKA
- IKKB
- KIAA0733
- KIAA0757
- KIAA0849
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- MIHB
- MIHC
- NEMO
- NRP
- OPTN
- OTDC1
- OTUD1
- OTUD7B
- OTUD7C
- PD1
- RACK1
- RBCK1
- RIP
- RIP1
- RIPK1
- RNF31
- RNF48
- RNF49
- RNF54
- SHARPIN
- SIPL1
- SPATA2
- TAB1
- TAB2
- TAB3
- TAK1
- TCF16
- TNF
- TNFA
- TNFAIP3
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF1
- TRAF2
- TRAP3
- UBCE7IP3
- UBP41
- UNP
- UNPH
- USP2
- USP21
- USP23
- USP4
- XAP3
- XAP4
- XIAP
- ZA20D1
- ZIBRA
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TNFR1-induced proapoptotic signaling
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- API1
- API2
- API3
- BIRC2
- BIRC3
- BIRC4
- C20orf18
- CASP8
- CYLD
- CYLD1
- DUBA7
- FADD
- FIP2
- GLC1E
- HIP7
- HYPL
- IAP3
- IKBKE
- IKKE
- IKKI
- KIAA0151
- KIAA0757
- KIAA0849
- MCH5
- MIB2
- MIHB
- MIHC
- MORT1
- NAK
- NRP
- OPTN
- OTDC1
- OTUD1
- OTUD7B
- OTUD7C
- PD1
- RBCK1
- RIP
- RIP1
- RIPK1
- RNF31
- RNF48
- RNF49
- RNF54
- SHARPIN
- SIPL1
- SKD
- SPATA2
- TBK1
- TNF
- TNFA
- TNFAIP3
- TNFAR
- TNFR1
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF2
- TRAP3
- UBCE7IP3
- UBP41
- UL36
- UNP
- UNPH
- USP2
- USP21
- USP23
- USP4
- XAP3
- XAP4
- XIAP
- ZA20D1
- ZIBRA
- ZZANK1
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RIPK1-mediated regulated necrosis
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- AIP1
- ALIX
- API1
- API2
- API3
- APO2
- APO2L
- APT1
- APT1LG1
- BIRC2
- BIRC3
- BIRC4
- CASP8
- CD95L
- CHIP
- DR4
- DR5
- ESA1
- FADD
- FAS
- FAS1
- FASL
- FASLG
- FLOT1
- FLOT2
- IAP3
- ICP6
- KIAA1375
- KILLER
- M17S1
- MCH5
- MDA9
- MIHB
- MIHC
- MLKL
- MORT1
- NS
- OGT
- PDCD6IP
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- RIR1
- RNF48
- RNF49
- SDCBP
- STUB1
- SYCL
- TNFRSF10A
- TNFRSF10B
- TNFRSF6
- TNFSF10
- TNFSF6
- TRADD
- TRAF2
- TRAIL
- TRAILR1
- TRAILR2
- TRAP3
- TRICK2
- XIAP
- ZTNFR9
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Regulation of necroptotic cell death
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- AIP1
- ALIX
- API1
- API2
- API3
- BIRC2
- BIRC3
- BIRC4
- CASP8
- CDC37
- CDC37A
- CHIP
- ESA1
- FADD
- FLOT1
- FLOT2
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- IAP3
- ITCH
- KIAA1375
- M17S1
- MCH5
- MDA9
- MIHB
- MIHC
- MLKL
- MORT1
- OGT
- PARK2
- PDCD6IP
- PELI1
- PRISM
- PRKN
- RIP
- RIP1
- RIP3
- RIPK1
- RIPK3
- RNF48
- RNF49
- RPS27A
- SDCBP
- STUB1
- SYCL
- TRADD
- TRAF2
- TRAP3
- UBA52
- UBA80
- UBB
- UBC
- UBCE7
- UBCEP1
- UBCEP2
- UBCH7
- UBE2L3
- XIAP
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