RHO GTPases activate PAKs
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- CALM
- CALM1
- CAM
- CAM1
- CDC42
- CTTN
- EMS1
- FLN
- FLN1
- FLNA
- KIAA0866
- KIAA2034
- LIMK
- LIMK1
- MBS
- MLC2
- MLCK
- MLCK1
- MRLC1
- MRLC2
- MYH10
- MYH11
- MYH14
- MYH9
- MYL12B
- MYL6
- MYL9
- MYLC2B
- MYLK
- MYLK1
- MYPT1
- MYPT2
- MYRL2
- NF2
- OPHN3
- PAK1
- PAK2
- PAK3
- PPP1CB
- PPP1R12A
- PPP1R12B
- RAC1
- SCH
- TC25
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Sodium/Calcium exchangers
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- CALM
- CALM1
- CAM
- CAM1
- CNC
- JSX
- KIAA0702
- KIAA1087
- NCKX1
- NCKX2
- NCKX3
- NCKX4
- NCKX5
- NCKX6
- NCLX
- NCX1
- NCX2
- NCX3
- SLC24A1
- SLC24A2
- SLC24A3
- SLC24A4
- SLC24A5
- SLC24A6
- SLC8A1
- SLC8A2
- SLC8A3
- SLC8B1
- SRI
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Activation of Ca-permeable Kainate Receptor
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- CALM
- CALM1
- CAM
- CAM1
- DLG1
- DLG3
- DLG4
- GLUR5
- GLUR6
- GLUR7
- GRIK
- GRIK1
- GRIK2
- GRIK3
- GRIK4
- GRIK5
- KIAA1232
- NCALD
- PSD95
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Cam-PDE 1 activation
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- CALM
- CALM1
- CAM
- CAM1
- PDE1A
- PDE1B
- PDE1C
- PDES1B
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CaM pathway
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Phase 1 - inactivation of fast Na+ channels
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- CALP
- CSEN
- DREAM
- KCHIP1
- KCHIP2
- KCHIP3
- KCHIP4
- KCND1
- KCND2
- KCND3
- KCNIP1
- KCNIP2
- KCNIP3
- KCNIP4
- KIAA1044
- VABP
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Calnexin/calreticulin cycle
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- CALR
- CANX
- CRTC
- ERP57
- ERP60
- G19P1
- G2AN
- GANAB
- GRP58
- KIAA0088
- PDIA3
- PRKCSH
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Assembly of Viral Components at the Budding Site
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- CALR
- CANX
- CRTC
- HA
- M
- NA
- NP
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Signal transduction by L1
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- CAML1
- CK2A1
- CK2A2
- CK2N
- CSNK2A1
- CSNK2A2
- CSNK2B
- EGFR
- ERBB
- ERBB1
- ERK1
- ERK2
- FNRA
- FNRB
- G5A
- GP2B
- GP3A
- HER1
- ITGA2B
- ITGA5
- ITGA9
- ITGAB
- ITGAV
- ITGB1
- ITGB3
- L1CAM
- MAP2K1
- MAP2K2
- MAPK1
- MAPK3
- MDF2
- MEK1
- MEK2
- MIC5
- MKK2
- MSK12
- MSK8
- NCAM
- NCAM1
- NRP
- NRP1
- PAK1
- PRKM1
- PRKM2
- PRKM3
- PRKMK1
- PRKMK2
- RAC1
- TC25
- VAV2
- VEGF165R
- VNRA
- VTNR
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Maturation of spike protein
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- CANX
- G19P1
- G2AN
- GANAB
- GCS1
- GGNT1
- GLCT1
- GLYT1
- KIAA0088
- MGAT
- MGAT1
- MOGS
- PRKCSH
- S
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Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)
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- CAP-1
- CD14
- CRAF1
- ESOP1
- FIP2
- GLC1E
- HIP7
- HYPL
- IKBKE
- IKKE
- IKKI
- IRF3
- IRF7
- ITRAF
- KIAA0151
- LY96
- MD2
- NAK
- NRP
- OPTN
- PRVTIRB
- PTP2C
- PTPN11
- RPS27A
- SHPTP2
- TANK
- TBK1
- TICAM1
- TICAM2
- TIRAP3
- TIRP
- TLR4
- TRAF2
- TRAF3
- TRAFAMN
- TRAM
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7
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- CAP-1
- CD14
- CRAF1
- ESOP1
- FIP2
- GLC1E
- HIP7
- HYPL
- IKBKE
- IKKE
- IKKI
- ITRAF
- KIAA0151
- LY96
- MD2
- NAK
- NRP
- OPTN
- PRVTIRB
- RPS27A
- TANK
- TBK1
- TICAM1
- TICAM2
- TIRAP3
- TIRP
- TLR4
- TRAF2
- TRAF3
- TRAFAMN
- TRAM
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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TICAM1-dependent activation of IRF3/IRF7
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- CAP-1
- CRAF1
- FIP2
- GLC1E
- HIP7
- HYPL
- IKBKE
- IKKE
- IKKI
- IRF3
- IRF7
- ITRAF
- KIAA0151
- NAK
- NRP
- OPTN
- PRVTIRB
- RPS27A
- TANK
- TBK1
- TICAM1
- TLR3
- TRAF2
- TRAF3
- TRAFAMN
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation
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- CAP-1
- CRAF1
- FIP2
- GLC1E
- HIP7
- HYPL
- IKBKE
- IKKE
- IKKI
- ITRAF
- KIAA0151
- NAK
- NRP
- OPTN
- PRVTIRB
- RPS27A
- TANK
- TBK1
- TICAM1
- TLR3
- TRAF2
- TRAF3
- TRAFAMN
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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TRAF3 deficiency - HSE
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- CAP-1
- CRAF1
- PRVTIRB
- TICAM1
- TLR3
- TRAF3
- TRAFAMN
- TRIF
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p53-Dependent G1 DNA Damage Response
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- CAP20
- CCN1
- CCNA
- CCNA1
- CCNA2
- CCNE
- CCNE1
- CCNE2
- CDK2
- CDKN1
- CDKN1A
- CDKN1B
- CDKN2
- CIP1
- KIP1
- MDA6
- PIC1
- SDI1
- WAF1
- p27
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Signaling by FLT3 fusion proteins
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- CAP20
- CD245
- CDKN1
- CDKN1A
- CEV14
- CIP1
- ETV6
- FIM
- GAB2
- GOLGB1
- GRB1
- HRAS
- HRAS1
- KIAA0216
- KIAA0571
- MDA6
- MYO18A
- MYSPDZ
- NOX4
- NRAS
- PIC1
- PIK3CA
- PIK3R1
- PIM1
- RAMP
- RENOX
- SDI1
- SOS1
- SPTB2
- SPTBN1
- STAT5
- STAT5A
- STAT5B
- TEL
- TEL1
- TIAF1
- TRIP11
- WAF1
- ZMYM2
- ZNF198
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Transcriptional activation of cell cycle inhibitor p21
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- CAP20
- CDKN1
- CDKN1A
- CIP1
- HZF
- MDA6
- P53
- PCBP4
- PIC1
- RZF
- SDI1
- TP53
- WAF1
- ZNF385
- ZNF385A
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Condensation of Prophase Chromosomes
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- CAPC
- CAPD3
- CAPE
- CAPH2
- CCNB
- CCNB1
- CDC2
- CDC28A
- CDK1
- CDKN1
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3-4
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H3FT
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST3H3
- HIST4H4
- KIAA0056
- KMT5A
- LUZP5
- MCPH1
- NCAPD3
- NCAPG2
- NCAPH2
- P34CDC2
- PLK
- PLK1
- PRSET7
- RB1
- SET
- SET07
- SET8
- SETD8
- SMC2
- SMC2L1
- SMC4
- SMC4L1
- TSH2B
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p75NTR recruits signalling complexes
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- CARDIAK
- DXS1179E
- IKBKB
- IKKB
- IRAK
- IRAK1
- MYD88
- NGF
- NGFB
- NGFR
- ORCA
- OSIL
- PRKCI
- RICK
- RIP2
- RIPK2
- RNF85
- RPS27A
- SQSTM1
- TNFRSF16
- TRAF6
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Pentose phosphate pathway
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- CARKL
- DERA
- G6PD
- PGD
- PGDH
- PGLS
- PGM2
- RBKS
- RBSK
- RPE
- RPEL1
- RPI
- RPIA
- SHPK
- TAL
- TALDO
- TALDO1
- TALDOR
- TKT
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Interleukin-1 processing
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- CASP1
- CTSG
- DFNA5L
- GSDMD
- GSDMDC1
- IGIF
- IL18
- IL1A
- IL1B
- IL1BC
- IL1BCE
- IL1F1
- IL1F2
- IL1F4
- LYT10
- NFKB1
- NFKB2
- NFKB3
- RELA
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NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
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- CASP10
- CASP8
- CHUK
- DDX58
- EFP
- FADD
- FIP3
- IFIH1
- IKBKB
- IKBKG
- IKKA
- IKKB
- IPS1
- KIAA1271
- MAVS
- MCH4
- MCH5
- MDA5
- MORT1
- NEMO
- RH116
- RIGI
- RIP
- RIP1
- RIPK1
- RNF135
- RNF147
- RNF87
- TCF16
- TRIM25
- TRIM4
- VISA
- ZNF147
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Apoptotic cleavage of cell adhesion proteins
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- CASP3
- CDH1
- CDHE
- CDHF4
- CDHF5
- CDHF6
- CPP32
- CTNNB
- CTNNB1
- DSG1
- DSG2
- DSG3
- DSP
- OCLN
- PKP1
- TJP1
- TJP2
- UVO
- X104
- ZO1
- ZO2
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Stimulation of the cell death response by PAK-2p34
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