GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **326 - 350** of **2074** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism
Spry regulation of FGF signaling	E3 ubiquitin-protein ligase CBL MAP kinase-interacting serine/threonine-protein kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Protein sprouty homolog 2 Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43597 P0CG47 P0CG48 P15056 P22681 P27361 P28482 P30153 P62714 P62979 P62987 P67775 Q06124 Q9BUB5	BRAF BRAF1 CBL CBL2 ERK1 ERK2 MAPK1 MAPK3 MKNK1 MNK1 PPP2CA PPP2CB PPP2R1A PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RAFB1 RNF55 RPS27A SHPTP2 SPRY2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Sphingolipid de novo biosynthesis	3-ketodihydrosphingosine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Casein kinase I isoform gamma-2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 type B Fatty acid 2-hydroxylase Multidrug resistance-associated protein 1 ORM1-like protein 1 ORM1-like protein 2 ORM1-like protein 3 Oxysterol-binding protein 1 Phosphatidylcholine Phosphatidylcholine Protein phosphatase 1L Serine palmitoyltransferase 1 Serine palmitoyltransferase 2 Serine palmitoyltransferase 3 Serine palmitoyltransferase small subunit A Serine palmitoyltransferase small subunit B Serine/threonine-protein kinase D1 Serine/threonine-protein kinase D2 Serine/threonine-protein kinase D3 Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 Sphingomyelin synthase-related protein 1 Sphingosine kinase 1 Sphingosine kinase 2 Sphingosine-1-phosphate transporter MFSD2B Sphingosine-1-phosphate transporter SPNS2 Vesicle-associated membrane protein-associated protein A Vesicle-associated membrane protein-associated protein B/C	A6NFX1 O15121 O15269 O15270 O43169 O94806 O95292 P22059 P27544 P33527 P78368 Q06136 Q15139 Q53FV1 Q5SGD2 Q6QHC5 Q6ZMG9 Q7L5A8 Q86VZ5 Q8IU89 Q8IVW8 Q8N138 Q8N5B7 Q8NFR3 Q8NHU3 Q969W0 Q96G23 Q96LT4 Q9BZL6 Q9HA82 Q9NRA0 Q9NUV7 Q9NYA1 Q9P0L0 Q9P0S3 Q9UNQ0	ABCC1 ABCG2 ABCP ADMP BCRP BCRP1 C14orf147 C14orf66 C20orf38 C3orf57 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CK1G2 CSNK1G2 CYB5B CYB5M DEGS1 DEGS2 DES1 EPK2 FA2H FAAH FAXDC1 FVT1 KDSR KIAA0526 LAG1 LASS1 LASS2 LASS3 LASS4 LASS5 LASS6 LCB1 LCB2 MFSD2B MLD MOB MRP MRP1 MXR OMB5 ORMDL1 ORMDL2 ORMDL3 OSBP OSBP1 PKD PKD1 PKD2 PP2CE PPM1L PRKCM PRKCN PRKD1 PRKD2 PRKD3 SAMD8 SDR35C1 SGMS1 SGMS2 SK1 SK2 SMS1 SMS2 SPHK SPHK1 SPHK2 SPK SPNS2 SPTLC1 SPTLC2 SPTLC2L SPTLC3 SPTSSA SPTSSB SSSPTA SSSPTB TMEM23 TMSG1 UOG1 VAP33 VAPA VAPB	Homo sapiens (human)
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member B1 Aldehyde dehydrogenase family 3 member B2 Alkaline ceramidase 1 Alkaline ceramidase 2 Alkaline ceramidase 3 Phospholipid phosphatase 1 Phospholipid phosphatase 2 Phospholipid phosphatase 3 Sphingosine-1-phosphate lyase 1 Sphingosine-1-phosphate phosphatase 1 Sphingosine-1-phosphate phosphatase 2	O14494 O14495 O43688 O95470 P43353 P48448 Q5QJU3 Q8IWX5 Q8TDN7 Q9BX95 Q9NUN7	ACER1 ACER2 ACER3 ALDH3B1 ALDH3B2 ALDH7 ALDH8 APHC ASAH3 ASAH3L KIAA1252 LPP1 LPP2 LPP3 PHCA PLPP1 PLPP2 PLPP3 PPAP2A PPAP2B PPAP2C SGPL1 SGPP1 SGPP2 SPP1	Homo sapiens (human)
Sperm Motility And Taxes	Cation channel sperm-associated auxiliary subunit beta Cation channel sperm-associated auxiliary subunit delta Cation channel sperm-associated auxiliary subunit gamma Cation channel sperm-associated protein 1 Cation channel sperm-associated protein 2 Cation channel sperm-associated protein 3 Cation channel sperm-associated protein 4 Potassium channel subfamily U member 1 Voltage-gated hydrogen channel 1	A8MYU2 Q6ZRH7 Q7RTX7 Q86XM0 Q86XQ3 Q8NEC5 Q96D96 Q96P56 Q9H7T0	C14orf161 C19orf15 CATSPER1 CATSPER2 CATSPER3 CATSPER4 CATSPERB CATSPERD CATSPERG HVCN1 KCNMA3 KCNMC1 KCNU1 SLO3 TMEM146 VSOP	Homo sapiens (human)
Specification of the neural plate border	Bone morphogenetic protein 4 Catenin beta-1 Fibroblast growth factor 4 Homeobox protein DLX-5 Homeobox protein GBX-2 Homeobox protein MSX-1 POU domain, class 5, transcription factor 1 Paired box protein Pax-3 Paired box protein Pax-7 Protein Wnt-3a Transcription factor 7-like 1 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor SOX-2 Transcriptional activator Myb Zinc finger protein ZIC 1	P05549 P08620 P10242 P12644 P23759 P23760 P28360 P35222 P48431 P52951 P56178 P56704 Q01860 Q15915 Q92481 Q92754 Q9HCS4	AP2TF BMP2B BMP4 CTNNB CTNNB1 DLX5 DVR4 FGF4 GBX2 HOX7 HST HSTF1 HUP1 HUP2 KS3 MSX1 MYB OCT3 OCT4 OTF3 PAX3 PAX7 POU5F1 SOX2 TCF3 TCF7L1 TFAP2 TFAP2A TFAP2B TFAP2C WNT3A ZIC ZIC1 ZNF201	Homo sapiens (human)
Specification of primordial germ cells	Bone morphogenetic protein 4 C-X-C chemokine receptor type 4 Eomesodermin homolog Homeobox protein NANOG Methylcytosine dioxygenase TET2 Nanos homolog 3 POU domain, class 5, transcription factor 1 PR domain zinc finger protein 1 Podoplanin Protein CBFA2T2 Transcription factor AP-2 gamma Transcription factor SOX-17	O43439 O75626 O95936 P12644 P60323 P61073 Q01860 Q6N021 Q86YL7 Q92754 Q9H6I2 Q9H9S0	BLIMP1 BMP2B BMP4 CBFA2T2 CXCR4 DVR4 EHT EOMES GP36 KIAA1546 MTGR1 NANOG NANOS3 NOS3 OCT3 OCT4 OTF3 PDPN POU5F1 PRDM1 SOX17 TBR2 TET2 TFAP2C	Homo sapiens (human)
Sorafenib-resistant PDGFR mutants	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA	Homo sapiens (human)
Sorafenib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Somitogenesis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Catenin beta-1 Delta-like protein 1 Delta-like protein 3 Ephrin type-A receptor 4 Lymphoid enhancer-binding factor 1 Mesoderm posterior protein 2 Mesogenin-1 Neurogenic locus notch homolog protein 1 Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein ripply2 Recombining binding protein suppressor of hairless T-box transcription factor TBX6 Transcription factor HES-7	A6NI15 O00231 O00232 O00487 O00548 O14818 O43242 O95947 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35222 P35998 P43686 P46531 P48556 P49720 P49721 P51665 P54764 P60896 P60900 P62191 P62195 P62333 Q06330 Q0VG99 Q13200 Q15008 Q16186 Q5TAB7 Q8NES3 Q99436 Q99460 Q9BYE0 Q9NYJ7 Q9UJU2 Q9UNM6	ADRM1 BHLHB37 BHLHC6 C6orf159 C7orf76 CTNNB CTNNB1 DLL1 DLL3 DSS1 EPHA4 GP110 HC2 HC3 HC8 HC9 HEK8 HES7 HSPC IGKJRB IGKJRB1 KIAA0107 LEF1 LFNG LMPX LMPY MB1 MESP2 MIP224 MOV34L MSGN1 MSS1 NOTCH1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBPJ RBPJK RBPSUH RIPPLY2 SCDO2 SEK SEM1 SHFDG1 SHFM1 SUG1 SUG2 TAN1 TBP1 TBP7 TBX6 TRAP2 TYRO1 X Y Z	Homo sapiens (human)
Sodium/Proton exchangers	Sodium/hydrogen exchanger 1 Sodium/hydrogen exchanger 2 Sodium/hydrogen exchanger 3 Sodium/hydrogen exchanger 4 Sodium/hydrogen exchanger 5 Sodium/hydrogen exchanger 6 Sodium/hydrogen exchanger 7 Sodium/hydrogen exchanger 8 Sodium/hydrogen exchanger 9	P19634 P48764 Q14940 Q6AI14 Q8IVB4 Q92581 Q96T83 Q9UBY0 Q9Y2E8	APNH1 KIAA0267 KIAA0939 NHE1 NHE2 NHE3 NHE4 NHE5 NHE6 NHE7 NHE8 NHE9 SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 SLC9A6 SLC9A7 SLC9A8 SLC9A9	Homo sapiens (human)
Sodium/Calcium exchangers	Calmodulin-1 Mitochondrial sodium/calcium exchanger protein Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sodium/potassium/calcium exchanger 1 Sodium/potassium/calcium exchanger 2 Sodium/potassium/calcium exchanger 3 Sodium/potassium/calcium exchanger 4 Sodium/potassium/calcium exchanger 5 Sorcin	O60721 P0DP23 P30626 P32418 P57103 Q6J4K2 Q71RS6 Q8NFF2 Q9HC58 Q9UI40 Q9UPR5	CALM CALM1 CAM CAM1 CNC JSX KIAA0702 KIAA1087 NCKX1 NCKX2 NCKX3 NCKX4 NCKX5 NCKX6 NCLX NCX1 NCX2 NCX3 SLC24A1 SLC24A2 SLC24A3 SLC24A4 SLC24A5 SLC24A6 SLC8A1 SLC8A2 SLC8A3 SLC8B1 SRI	Homo sapiens (human)
Sodium-coupled sulphate, di- and tri-carboxylate transporters	Na(+)/citrate cotransporter Na(+)/dicarboxylate cotransporter 3 Solute carrier family 13 member 1 Solute carrier family 13 member 2 Solute carrier family 13 member 4	Q13183 Q86YT5 Q8WWT9 Q9BZW2 Q9UKG4	NACT NADC1 NADC3 NAS1 NASI1 SDCT1 SDCT2 SLC13A1 SLC13A2 SLC13A3 SLC13A4 SLC13A5 SUT1	Homo sapiens (human)
Sodium-coupled phosphate cotransporters	Sodium-dependent phosphate transporter 1 Sodium-dependent phosphate transporter 2	Q08357 Q8WUM9	GLVR1 GLVR2 PIT1 PIT2 SLC20A1 SLC20A2	Homo sapiens (human)
Smooth Muscle Contraction	Aldehyde dehydrogenase, mitochondrial Annexin A1 Annexin A2 Annexin A6 Caldesmon Calmodulin-1 Caveolin-3 Dysferlin Guanylate cyclase soluble subunit alpha-1 Guanylate cyclase soluble subunit alpha-2 Guanylate cyclase soluble subunit beta-1 Guanylate cyclase soluble subunit beta-2 Integrin alpha-1 Integrin beta-5 Leiomodin-1 Myosin light chain 5 Myosin light chain 6B Myosin light chain kinase, smooth muscle Myosin light polypeptide 6 Myosin regulatory light chain 10 Myosin regulatory light chain 11 Myosin regulatory light chain 12A Myosin regulatory light chain 12B Myosin regulatory light chain 2, atrial isoform Myosin regulatory light polypeptide 9 Myosin-11 Paxillin Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Sorbin and SH3 domain-containing protein 1 Talin-1 Tripartite motif-containing protein 72 Tropomyosin alpha-1 chain Tropomyosin alpha-3 chain Tropomyosin alpha-4 chain Tropomyosin beta chain Vinculin Vinexin Voltage-dependent T-type calcium channel subunit alpha-1G Voltage-dependent T-type calcium channel subunit alpha-1H Voltage-dependent T-type calcium channel subunit alpha-1I cGMP-specific 3',5'-cyclic phosphodiesterase	O14950 O43497 O60504 O75343 O75923 O76074 O95180 P04083 P05091 P06753 P07355 P07951 P08133 P09493 P0DP23 P14649 P18084 P18206 P19105 P24844 P29536 P33402 P35749 P49023 P56199 P56539 P60660 P67936 Q01449 Q02045 Q02108 Q02153 Q05682 Q13153 Q13177 Q15746 Q6ZMU5 Q96A32 Q9BUA6 Q9BX66 Q9P0X4 Q9Y490	ALDH2 ALDM ANX1 ANX2 ANX2L4 ANX6 ANXA1 ANXA2 ANXA6 C15orf13 CACNA1G CACNA1H CACNA1I CAD CAL1H CALD1 CALM CALM1 CAM CAM1 CAV3 CDM DYSF FER1L1 GUC1A2 GUC1A3 GUC1B3 GUCSA2 GUCSA3 GUCSB3 GUCY1A1 GUCY1A2 GUCY1A3 GUCY1B1 GUCY1B2 GUCY1B3 HSRLC ITGA1 ITGB5 KIAA0866 KIAA0894 KIAA1027 KIAA1120 KIAA1123 KIAA1296 LMOD1 LPC1 LPC2D MG53 MLC1SA MLC2 MLCB MLCK MLCK1 MRLC1 MRLC2 MRLC3 MYH11 MYL10 MYL11 MYL12A MYL12B MYL2A MYL5 MYL6 MYL6B MYL7 MYL9 MYLC2A MYLC2B MYLC2PL MYLK MYLK1 MYLPF MYRL2 PAK1 PAK2 PDE5 PDE5A PLRLC PXN RLC SCAM1 SH3D5 SORBS1 SORBS3 TLN TLN1 TMSA TMSB TPM1 TPM2 TPM3 TPM4 TRIM72 VCL	Homo sapiens (human)
Small interfering RNA (siRNA) biogenesis	Endoribonuclease Dicer Interferon-inducible double-stranded RNA-dependent protein kinase activator A Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 RISC-loading complex subunit TARBP2 Translin-associated protein X Translin	O75569 Q15631 Q15633 Q99598 Q9H9G7 Q9HCK5 Q9UKV8 Q9UL18 Q9UPY3	AGO1 AGO2 AGO3 AGO4 DICER DICER1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 HERNA KIAA0928 KIAA1567 PACT PRKRA RAX TARBP2 TRAX TRBP TSN TSNAX	Homo sapiens (human)
Signalling to p38 via RIT and RIN	Beta-nerve growth factor GTP-binding protein Rit1 GTP-binding protein Rit2 High affinity nerve growth factor receptor Serine/threonine-protein kinase B-raf	P01138 P04629 P15056 Q92963 Q99578	BRAF BRAF1 MTC NGF NGFB NTRK1 RAFB1 RIBB RIN RIT RIT1 RIT2 ROC1 ROC2 TRK TRKA	Homo sapiens (human)
Signalling to STAT3	Beta-nerve growth factor High affinity nerve growth factor receptor Signal transducer and activator of transcription 3	P01138 P04629 P40763	APRF MTC NGF NGFB NTRK1 STAT3 TRK TRKA	Homo sapiens (human)
Signalling to RAS	Beta-nerve growth factor GTPase HRas GTPase NRas High affinity nerve growth factor receptor SHC-transforming protein 1 SHC-transforming protein 2 SHC-transforming protein 3 Son of sevenless homolog 1	P01111 P01112 P01138 P04629 P29353 P98077 Q07889 Q92529	HRAS HRAS1 MTC NGF NGFB NRAS NSHC NTRK1 SCK SHC SHC1 SHC2 SHC3 SHCA SHCB SHCC SOS1 TRK TRKA	Homo sapiens (human)
Signalling to ERK5	Dual specificity mitogen-activated protein kinase kinase 5 Mitogen-activated protein kinase 7	Q13163 Q13164	BMK1 ERK5 MAP2K5 MAPK7 MEK5 MKK5 PRKM7 PRKMK5	Homo sapiens (human)
Signaling downstream of RAS mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB	Homo sapiens (human)
Signaling by plasma membrane FGFR1 fusions	BAG family molecular chaperone regulator 4 Erlin-2 Fibroblast growth factor receptor 1	O94905 O95429 P11362	BAG4 BFGFR C8orf2 CEK ERLIN2 FGFBR FGFR1 FLG FLT2 HBGFR SODD SPFH2	Homo sapiens (human)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	GTPase HRas GTPase NRas Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O00459 O60674 P01111 P01112 P06239 P06241 P07947 P07948 P10721 P27986 P40763 P42224 P42229 P42336 P51692 Q07889 Q92569	APRF FYN GRB1 HRAS HRAS1 JAK2 JTK8 KIT LCK LYN NRAS PIK3CA PIK3R1 PIK3R2 PIK3R3 SCFR SOS1 STAT1 STAT3 STAT5 STAT5A STAT5B YES YES1	Homo sapiens (human)
Signaling by moderate kinase activity BRAF mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB	Homo sapiens (human)
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	Bridging integrator 2 Golgin subfamily A member 4 KN motif and ankyrin repeat domain-containing protein 1 Transcription factor ETV6 Vascular endothelial growth factor receptor 2	P35968 P41212 Q13439 Q14678 Q9UBW5	ANKRD15 BIN2 BRAP1 ETV6 FLK1 GOLGA4 KANK KANK1 KDR KIAA0172 TEL TEL1 VEGFR2	Homo sapiens (human)
Signaling by kinase domain mutants of KIT	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)

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