GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **2074** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Defective ABCB6 causes MCOPCB7	ATP-binding cassette sub-family B member 6	Q9NP58	ABCB6 MTABC3 PRP UMAT	Homo sapiens (human)
APAP ADME	ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 Aminoacylase-1 Arylamine N-acetyltransferase 1 Arylamine N-acetyltransferase 2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Glutathione S-transferase Mu 1 Glutathione S-transferase P Glutathione S-transferase theta-1 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Multidrug resistance-associated protein 1 Putative glutathione hydrolase 3 proenzyme Sulfotransferase 1A1 Sulfotransferase 1A3 Sulfotransferase 1A4 Sulfotransferase 1C4 Sulfotransferase 1E1 Sulfotransferase 2A1 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A10 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2B15	A6NGU5 O15438 O15439 O15440 O60656 O75897 P05181 P09211 P09488 P0DMM9 P0DMN0 P11245 P18440 P19224 P19440 P22309 P30711 P33527 P36269 P49888 P50225 P54855 Q03154 Q06520 Q6P531 Q92887 Q96KP4 Q9HAW8 Q9UJ14 Q9UNQ0	AAC1 AAC2 ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABCP ACY1 BCRP BCRP1 CMOAT CMOAT1 CMOAT2 CMRP CN2 CNDP2 CPGL CYP2E CYP2E1 FAEES3 GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GNT1 GST1 GST3 GSTM1 GSTP1 GSTT1 HEL-S-13 HST MLP2 MOATB MRP MRP1 MRP2 MRP3 MRP4 MRP5 MXR NAT1 NAT2 PEPA STD STE STM STP STP1 SULT1A1 SULT1A3 SULT1A4 SULT1C2 SULT1C4 SULT1E1 SULT2A1 UGT1 UGT1A1 UGT1A10 UGT1A6 UGT1A9 UGT2B15 UGT2B8	Homo sapiens (human)
Aspirin ADME	ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial Acyl-coenzyme A synthetase ACSM2B, mitochondrial Acyl-coenzyme A synthetase ACSM4, mitochondrial Acyl-coenzyme A synthetase ACSM5, mitochondrial Albumin Basigin Cholinesterase Cocaine esterase Cytochrome P450 2C19 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 2E1 Cytochrome P450 3A4 Glycine N-acyltransferase-like protein 1 Glycine N-acyltransferase-like protein 2 Glycine N-acyltransferase-like protein 3 Glycine N-acyltransferase Liver carboxylesterase 1 Monocarboxylate transporter 1 Solute carrier family 22 member 7 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A4 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 1A7 UDP-glucuronosyltransferase 1A8 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2A1 UDP-glucuronosyltransferase 2A2 UDP-glucuronosyltransferase 2A3 UDP-glucuronosyltransferase 2B10 UDP-glucuronosyltransferase 2B11 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B28 UDP-glucuronosyltransferase 2B4 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase 3A1 UDP-glucuronosyltransferase 3A2	O00748 O15438 O60656 O75310 O75795 P02768 P05181 P06133 P06276 P08684 P0C7M7 P0DTE4 P0DTE5 P10632 P10635 P11712 P16662 P19224 P22309 P22310 P23141 P33261 P35503 P35504 P35613 P36537 P53985 P54855 Q08AH3 Q3SY77 Q5SZD4 Q68CK6 Q6IB77 Q6NUN0 Q6NUS8 Q6UWM9 Q8WU03 Q92887 Q969I3 Q9BY64 Q9HAW7 Q9HAW9 Q9Y694	ABCC2 ABCC3 ACGNAT ACSM2 ACSM2A ACSM2B ACSM4 ACSM5 ALB BCHE BSG C6orf140 CAT CES1 CES2 CHE1 CMOAT CMOAT1 CMOAT2 CMRP CYP2C10 CYP2C19 CYP2C8 CYP2C9 CYP2D6 CYP2DL1 CYP2E CYP2E1 CYP3A3 CYP3A4 GAT GLYAT GLYATL1 GLYATL2 GLYATL3 GNAT GNT1 ICE MACS2 MACS3 MCT1 MLP2 MRP2 MRP3 NLT OAT2 SES1 SLC16A1 SLC22A7 UGT1 UGT1A1 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UGT2B8 UGT3A1 UGT3A2 UGTB2B9	Homo sapiens (human)
Atorvastatin ADME	ATP-binding cassette sub-family C member 2 ATP-dependent translocase ABCB1 Cytochrome P450 3A4 Serum paraoxonase/arylesterase 1 Serum paraoxonase/lactonase 3 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 UDP-glucuronosyltransferase 1A3	P08183 P08684 P27169 P35503 Q15166 Q92887 Q9NPD5 Q9Y6L6	ABCB1 ABCC2 CMOAT CMOAT1 CMRP CYP3A3 CYP3A4 GNT1 LST1 LST2 MDR1 MRP2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC PGY1 PON PON1 PON3 SLC21A6 SLC21A8 SLCO1B1 SLCO1B3 UGT1 UGT1A3	Homo sapiens (human)
Heme degradation	ATP-binding cassette sub-family C member 2 Albumin Beta-glucuronidase Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Flavin reductase (NADPH) Glutathione S-transferase A1 Heme oxygenase 1 Heme oxygenase 2 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A4	P02768 P07148 P08263 P09601 P22309 P22310 P30043 P30519 P33527 P53004 Q8VNV4 Q92887 Q9NPD5 Q9UNQ0 Q9Y6L6	ABCC1 ABCC2 ABCG2 ABCP ALB BCRP BCRP1 BLVR BLVRA BLVRB BVR CMOAT CMOAT1 CMRP FABP1 FABPL FLR GNT1 GSTA1 HMOX1 HMOX2 HO HO1 HO2 LST1 LST2 MRP MRP1 MRP2 MXR OATP1B1 OATP1B3 OATP2 OATP8 OATPC SCAN SLC21A6 SLC21A8 SLCO1B1 SLCO1B3 UGT1 UGT1A1 UGT1A4	Homo sapiens (human)
Defective ABCC2 causes DJS	ATP-binding cassette sub-family C member 2	Q92887	ABCC2 CMOAT CMOAT1 CMRP MRP2	Homo sapiens (human)
NFE2L2 regulating MDR associated enzymes	ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family F member 2 Broad substrate specificity ATP-binding cassette transporter ABCG2 CREB-binding protein Histone acetyltransferase p300 Multidrug resistance-associated protein 1 Nuclear factor erythroid 2-related factor 2 Transcription factor MafK	O15438 O60675 P33527 Q09472 Q16236 Q92793 Q9UG63 Q9UNQ0	ABCC1 ABCC3 ABCF2 ABCG2 ABCP BCRP BCRP1 CBP CMOAT2 CREBBP EP300 MAFK MLP2 MRP MRP1 MRP3 MXR NFE2L2 NRF2 P300	Homo sapiens (human)
Recycling of bile acids and salts	ATP-binding cassette sub-family C member 3 Albumin Bile acid receptor Bile acid-CoA Bile salt export pump Gastrotropin Hepatic sodium/bile acid cotransporter Ileal sodium/bile acid cotransporter Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Organic solute transporter subunit alpha Organic solute transporter subunit beta Retinoic acid receptor RXR-alpha Solute carrier organic anion transporter family member 1A2 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 StAR-related lipid transfer protein 5	O15438 O95342 P02768 P19793 P46721 P51161 Q12908 Q14032 Q14973 Q15596 Q15788 Q86UW1 Q86UW2 Q96RI1 Q9NPD5 Q9NSY2 Q9Y2P5 Q9Y6L6	ABCB11 ABCC3 ACSB ACSVL6 ALB ASBT BAAT BAR BHLHE74 BHLHE75 BSEP CMOAT2 FABP6 FACVL3 FATP5 FXR HRR1 ILBP ILLBP ISBT LST1 LST2 MLP2 MRP3 NCOA1 NCOA2 NR1H4 NR2B1 NTCP NTCP2 OATP OATP1 OATP1A2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC OSTA OSTB RIP14 RXRA SLC10A1 SLC10A2 SLC21A3 SLC21A6 SLC21A8 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B1 SLCO1B3 SRC1 SRC2 STARD5 TIF2	Homo sapiens (human)
Azathioprine ADME	ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 Equilibrative nucleoside transporter 1 Equilibrative nucleoside transporter 2 GMP synthase [glutamine-hydrolyzing] Glutathione S-transferase A1 Glutathione S-transferase A2 Glutathione S-transferase Mu 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanylate kinase Hypoxanthine-guanine phosphoribosyltransferase Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleotide triphosphate diphosphatase NUDT15 Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Sodium/nucleoside cotransporter 2 Solute carrier family 28 member 3 Thiopurine S-methyltransferase Xanthine dehydrogenase/oxidase	O15439 O15440 O43868 P00492 P08263 P09210 P09488 P12268 P15498 P15531 P20839 P22392 P47989 P49915 P51580 P52735 P63000 Q14542 Q16774 Q99808 Q9HAS3 Q9NV35 Q9UKW4	ABCC4 ABCC5 CNT2 CNT3 DER12 ENT1 ENT2 GMK GMPK GMPS GST1 GST2 GSTA1 GSTA2 GSTM1 GUK1 HNP36 HPRT HPRT1 IMPD1 IMPD2 IMPDH1 IMPDH2 MOATB MRP4 MRP5 MTH2 NDPKA NM23 NM23B NME1 NME2 NUDT15 RAC1 SLC28A2 SLC28A3 SLC29A1 SLC29A2 TC25 TPMT VAV VAV1 VAV2 VAV3 XDH XDHA	Homo sapiens (human)
Platelet degranulation	ATP-binding cassette sub-family C member 4 Adenylyl cyclase-associated protein 1 Albumin Alpha-1-acid glycoprotein 1 Alpha-1-acid glycoprotein 2 Alpha-1-antichymotrypsin Alpha-1-antitrypsin Alpha-1B-glycoprotein Alpha-2-HS-glycoprotein Alpha-2-antiplasmin Alpha-2-macroglobulin Alpha-actinin-1 Alpha-actinin-2 Alpha-actinin-4 Amyloid beta precursor like protein 2 Amyloid-beta precursor protein Annexin A5 Apolipoprotein A-I Beta-2-glycoprotein 1 Bromodomain and PHD finger-containing protein 3 CD109 antigen CD63 antigen CD9 antigen CYFIP-related Rac1 interactor B Calmodulin-1 Calumenin Cathepsin W Chitinase domain-containing protein 1 Clusterin Coagulation factor V Coagulation factor VIII Coagulation factor XIII A chain Cofilin-1 Complement factor D Endonuclease domain-containing 1 protein Endoplasmic reticulum chaperone BiP Extracellular matrix protein 1 Fermitin family homolog 3 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Filamin-A Fructose-bisphosphate aldolase A GTP-binding protein 2 Galectin-3-binding protein Growth arrest-specific protein 6 Hepatocyte growth factor Histidine-rich glycoprotein Hsp90 co-chaperone Cdc37-like 1 Immunoglobulin superfamily containing leucine-rich repeat protein Insulin-like growth factor I Insulin-like growth factor II Integrin alpha-IIb Integrin beta-3 Inter-alpha-trypsin inhibitor heavy chain H3 Inter-alpha-trypsin inhibitor heavy chain H4 Intracellular hyaluronan-binding protein 4 Kallistatin Kininogen-1 LHFPL tetraspan subfamily member 2 protein Left-right determination factor 2 Lymphocyte antigen 6 complex locus protein G6f Lysosome-associated membrane glycoprotein 2 MICOS complex subunit MIC27 Melanoma-associated antigen D2 Mesencephalic astrocyte-derived neurotrophic factor Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 3 Multimerin-1 NADH-cytochrome b5 reductase 1 NHL repeat-containing protein 2 Obg-like ATPase 1 P-selectin Peptidyl-prolyl cis-trans isomerase A Phosphatase and actin regulator 2 Plasma protease C1 inhibitor Plasminogen activator inhibitor 1 Plasminogen Platelet basic protein Platelet endothelial cell adhesion molecule Platelet factor 4 Platelet glycoprotein 4 Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase-like Pro-epidermal growth factor Profilin-1 Prosaposin Protein FAM3C Protein disulfide-isomerase TMX3 Protocadherin-7 Putative beta-actin-like protein 3 Ras-related protein Rab-27B Retinoic acid receptor responder protein 2 SPARC Saccharopine dehydrogenase-like oxidoreductase Secreted phosphoprotein 24 Secretogranin-3 Selenoprotein P Serglycin Serotransferrin Sulfhydryl oxidase 1 Superoxide dismutase [Cu-Zn] Synaptotagmin-like protein 4 Syntaxin-binding protein 2 Talin-1 Testis-expressed protein 264 Tetranectin Thrombospondin-1 Thymosin beta-4 Titin Torsin-4A Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein Transgelin-2 Tubulin alpha-4A chain Vascular endothelial growth factor A, long form Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D Vesicle transport through interaction with t-SNAREs homolog 1B Vinculin Vitamin K-dependent protein S WD repeat-containing protein 1 von Willebrand factor	O00194 O00292 O00391 O14498 O15439 O43707 O43852 O43915 O60245 O75083 O75167 O94919 P00441 P00451 P00488 P00746 P00747 P01009 P01011 P01023 P01033 P01042 P01127 P01133 P01137 P01344 P02647 P02671 P02675 P02679 P02749 P02751 P02763 P02765 P02768 P02775 P02776 P02787 P04075 P04196 P04217 P04275 P05019 P05067 P05106 P05121 P05155 P05452 P07225 P07602 P07737 P07996 P08514 P08567 P08697 P08758 P08962 P09486 P0DP23 P10124 P10600 P10909 P11021 P12259 P12814 P13473 P14210 P15692 P16109 P16284 P16671 P18206 P19652 P21333 P21926 P23528 P29622 P35609 P35625 P37802 P49765 P49767 P49908 P55145 P56202 P61812 P62328 P62937 P68366 Q01518 Q06033 Q06481 Q08380 Q13103 Q13201 Q14393 Q14624 Q15833 Q16610 Q5JVS0 Q5SQ64 Q6UXV4 Q6YHK3 Q6ZUX7 Q7L3B6 Q86UX7 Q8NBF2 Q8NBM8 Q8NBX0 Q8WXD2 Q8WZ42 Q92520 Q96C24 Q96JJ7 Q99969 Q9BWS9 Q9BX10 Q9BYX7 Q9NTK5 Q9NUQ9 Q9NXH8 Q9UEU0 Q9UHQ9 Q9ULD4 Q9UNF1 Q9Y490 Q9Y6I9	A1BG A2M A4 AACT AAP AAT ABCC4 ACTBL3 ACTN1 ACTN2 ACTN4 AD1 AGP1 AGP2 AHSG ALB ALDA ALDOA ANX5 ANXA5 APLP2 APOA1 APOH APOJ APOOL APP APPL2 ARMET ARP AXLLG B2G1 BCG1 BDK BHPCDH BRPF3 C1IN C1NH C6orf21 C6orf56 C9orf167 CALM CALM1 CALU CAM CAM1 CAP CAP1 CD109 CD36 CD63 CD9 CDC37B CDC37L1 CFD CFL CFL1 CHID1 CLEC3B CLGI CLI CLU CPAMD5 CPAMD7 CTAP3 CTSW CXCL4 CXCL7 CXorf33 CYB5R1 CYPA CYRI CYRIB DF EBAF ECM ECM1 EGF EMILIN4 ENDOD1 ENX2 F13A F13A1 F5 F8 F8C F8VWF FAM121A FAM3C FAM49B FERMT3 FETUA FGA FGB FGG FIGF FLN FLN1 FLNA FN FN1 G6F GAS6 GLBA GMRP GP2B GP3A GP3B GP4 GPIA* GRMP GRP78 GTPBP2 GTPBP9 HABP4 HARC HGF HPTA HRG HSPA5 IBP1 IGF1 IGF2 IHRP ILEI ISLR ITGA2B ITGAB ITGB3 ITIH3 ITIH4 ITIHL1 KIAA0120 KIAA0206 KIAA0680 KIAA0830 KIAA1027 KIAA1286 KIAA1830 KIND3 KNG KNG1 KST KUB1 LAMP2 LEFTA LEFTY2 LEFTYA LGALS3BP LHFPL2 LY6G6D LY6G6F M2BP MAGED2 MANF MIC27 MIC3 MIG2B MLA1 MMRN MMRN1 MOATB MRP4 NG32 NHLRC2 NQO3A2 OLA1 ON ORM1 ORM2 P47 PAI1 PCDH7 PCYOX1L PDGF2 PDGFB PECAM1 PF4 PFD PFN1 PHACTR2 PI PI4 PK120 PLANH1 PLEK PLG PLI POTEKP PP4 PPBP PPIA PRG PRG1 PROS PROS1 PSAP QSCN6 QSOX1 RAB27B RARRES2 SAP1 SCCPDH SCG3 SCYB4 SCYB7 SELENOP SELP SEPP1 SERPINA1 SERPINA3 SERPINA4 SERPINE1 SERPINF2 SERPING1 SIS SOD1 SPARC SPP2 SPP24 SRGN STXBP2 SYTL4 TAGLN2 TB4X TEX264 TF TGB1 TGFB TGFB1 TGFB2 TGFB3 TGFB4 THBGB1 THBS1 THYB4 TIG2 TIMP TIMP1 TIMP3 TLN TLN1 TMSB4 TMSB4X TMX3 TNA TOR4A TSP TSP1 TSPAN29 TSPAN30 TTN TUBA1 TUBA4A TXNDC10 UNC18B URP2 VCL VEGF VEGFA VEGFB VEGFC VEGFD VRF VTI1 VTI1B VTI1L VTI1L1 VTI2 VWF WDR1 ZSIG11	Homo sapiens (human)
Hyaluronan biosynthesis and export	ATP-binding cassette sub-family C member 5 Cell migration-inducing and hyaluronan-binding protein Hyaluronan synthase 1 Hyaluronan synthase 2 Hyaluronan synthase 3	O00219 O15440 Q8WUJ3 Q92819 Q92839	ABCC5 CEMIP HAS HAS1 HAS2 HAS3 HYBID KIAA1199 MRP5	Homo sapiens (human)	G35674CY
Defective ABCC6 causes PXE	ATP-binding cassette sub-family C member 6	O95255	ABCC6 ARA MRP6	Homo sapiens (human)
ATP sensitive Potassium channels	ATP-binding cassette sub-family C member 8 ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11 ATP-sensitive inward rectifier potassium channel 8	O60706 Q09428 Q14654 Q15842	ABCC8 ABCC9 HRINS KCNJ11 KCNJ8 SUR SUR1 SUR2	Homo sapiens (human)
Regulation of insulin secretion	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Insulin Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 S-adenosylhomocysteine hydrolase-like protein 1 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Synaptosomal-associated protein 25 Synaptotagmin-5 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel subunit alpha-2/delta-2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00445 O00555 O43865 O95398 P01308 P04899 P11166 P11168 P17612 P22612 P22694 P54284 P60880 P61764 P63027 P63096 Q01668 Q08289 Q09428 Q13936 Q14571 Q14573 Q14643 Q14654 Q15878 Q16623 Q8WZA2 Q9NY47	ABCC8 AHCYL1 CACH2 CACH3 CACH4 CACH6 CACN2 CACN3 CACN4 CACNA1A CACNA1C CACNA1D CACNA1E CACNA2D2 CACNB2 CACNB3 CACNL1A1 CACNL1A2 CACNL1A4 CACNL1A6 CACNLB2 CACNLB3 CCHL1A1 CCHL1A2 CGEF1 CGEF2 DCAL EPAC EPAC1 EPAC2 GLUT1 GLUT2 GNAI1 GNAI2 GNAI2B HRINS INS INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KCNJ11 KIAA0558 MYSB PKACA PRKACA PRKACB PRKACG RAPGEF3 RAPGEF4 SLC2A1 SLC2A2 SNAP SNAP25 STX1 STX1A STXBP1 SUR SUR1 SYB2 SYT5 UNC18A VAMP2 XPVKONA	Homo sapiens (human)	G58161NS
Defective ABCC8 can cause hypo- and hyper-glycemias	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11	Q09428 Q14654	ABCC8 HRINS KCNJ11 SUR SUR1	Homo sapiens (human)
Ion homeostasis	ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11 Aspartyl/asparaginyl beta-hydroxylase Calcium release-activated calcium channel protein 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Cardiac phospholamban Chloride intracellular channel protein 2 FXYD domain-containing ion transport regulator 3 FXYD domain-containing ion transport regulator 4 FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Myotonin-protein kinase Nitric oxide synthase 1 Peptidyl-prolyl cis-trans isomerase FKBP1B Phospholemman Plasma membrane calcium-transporting ATPase 1 Plasma membrane calcium-transporting ATPase 2 Plasma membrane calcium-transporting ATPase 3 Plasma membrane calcium-transporting ATPase 4 Protein orai-2 Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 S-adenosylhomocysteine hydrolase-like protein 1 Sarcolipin Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha-3 Sodium/potassium-transporting ATPase subunit alpha-4 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta-2 Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit gamma Sorcin Stromal interaction molecule 1 Triadin Troponin I, cardiac muscle cAMP-dependent protein kinase catalytic subunit alpha	O00168 O00631 O14983 O15247 O43865 O60706 P05023 P05026 P0DP23 P13637 P14415 P16615 P17612 P19429 P20020 P21817 P23634 P26678 P29475 P30626 P32418 P48995 P50993 P54709 P54710 P57103 P58549 P59646 P68106 Q01814 Q09013 Q12797 Q13061 Q13554 Q13555 Q13557 Q13586 Q13733 Q14571 Q14573 Q14643 Q14654 Q14802 Q15413 Q16720 Q92736 Q93084 Q96D31 Q96SN7 Q9H0Q3 Q9UPR5 Q9UQM7	ABCC9 AHCYL1 ASPH ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1AL2 ATP1B ATP1B1 ATP1B2 ATP1B3 ATP1C ATP1G1 ATP2A1 ATP2A2 ATP2A3 ATP2B ATP2B1 ATP2B2 ATP2B3 ATP2B4 BAH C7orf19 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CBCIP2 CLIC2 CNC CRACM1 DCAL DM1PK DMPK FKBP12.6 FKBP1B FKBP1L FKBP9 FXYD1 FXYD2 FXYD3 FXYD4 FXYD6 FXYD7 GOK HBRR INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KCNJ11 KIAA0778 KIAA0968 KIAA1087 MAT8 MDPK MXRA1 NCX1 NCX2 NCX3 NOS1 ORAI1 ORAI2 OTK4 PKACA PLB PLM PLML PLN PMCA1 PMCA2 PRKACA RYDR RYR1 RYR2 RYR3 SLC8A1 SLC8A2 SLC8A3 SLN SRI STIM1 SUR2 TMEM142A TMEM142B TNNC1 TNNI3 TRDN TRP1 TRPC1 XPVKONA	Homo sapiens (human)
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome	ATP-binding cassette sub-family C member 9 ATP-sensitive inward rectifier potassium channel 11	O60706 Q14654	ABCC9 KCNJ11 SUR2	Homo sapiens (human)
Class I peroxisomal membrane protein import	ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 Acyl-CoA-binding domain-containing protein 5 Ganglioside-induced differentiation-associated protein 1 Mitochondrial fission 1 protein Outer mitochondrial transmembrane helix translocase Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Peroxisomal membrane protein 11B Peroxisomal membrane protein 2 Peroxisomal membrane protein 4 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal membrane protein PEX16 Peroxisomal membrane protein PMP34 Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 2	O00623 O43808 O75381 O96011 P28288 P28328 P33897 P40855 P56589 Q5T8D3 Q7Z412 Q8NBU5 Q8TB36 Q92968 Q9NR77 Q9UBJ2 Q9Y3D6 Q9Y5Y5 Q9Y6I8	ABCD1 ABCD2 ABCD3 ACBD5 ALD ALD1 ALDL1 ALDR ALDRP ATAD1 FIS1 GDAP1 HK33 KIAA1996 PAF1 PAF3 PEX11B PEX12 PEX13 PEX14 PEX16 PEX19 PEX2 PEX26 PEX3 PMP22 PMP24 PMP3 PMP34 PMP35 PMP70 PXF PXMP1 PXMP2 PXMP3 PXMP4 RNF72 SLC25A17 TTC11	Homo sapiens (human)
Linoleic acid (LA) metabolism	ATP-binding cassette sub-family D member 1 Acyl-CoA (8-3)-desaturase Acyl-CoA 6-desaturase Long-chain-fatty-acid--CoA ligase 1 Very long chain fatty acid elongase 1 Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 3 Very long chain fatty acid elongase 5	O60427 O95864 P33121 P33897 Q9BW60 Q9HB03 Q9NXB9 Q9NYP7	ABCD1 ACSL1 ALD CIG30 ELG3 ELOVL1 ELOVL2 ELOVL3 ELOVL5 FACL1 FACL2 FADS1 FADS2 FADSD5 LACS LACS1 LACS2 SSC1 SSC2	Homo sapiens (human)
Defective ABCD1 causes ALD	ATP-binding cassette sub-family D member 1	P33897	ABCD1 ALD	Homo sapiens (human)
HDL remodeling	ATP-binding cassette sub-family G member 1 Albumin Apolipoprotein A-I Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Cholesteryl ester transfer protein Endothelial lipase Phosphatidylcholine-sterol acyltransferase	P02647 P02649 P02655 P02656 P02768 P04180 P11597 P45844 Q9Y5X9	ABC8 ABCG1 ALB APC2 APOA1 APOC2 APOC3 APOE CETP LCAT LIPG WHT1	Homo sapiens (human)
Defective ABCG5 causes sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8	Homo sapiens (human)
Defective ABCG8 causes GBD4 and sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8	Homo sapiens (human)
Telomere Extension By Telomerase	ATP-dependent DNA helicase PIF1 Adrenocortical dysplasia protein homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 H/ACA ribonucleoprotein complex subunit 1 H/ACA ribonucleoprotein complex subunit 2 H/ACA ribonucleoprotein complex subunit 3 H/ACA ribonucleoprotein complex subunit DKC1 Protection of telomeres protein 1 Protein SHQ1 homolog Regulator of telomere elongation helicase 1 RuvB-like 1 RuvB-like 2 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 3 TERF1-interacting nuclear factor 2 Telomerase Cajal body protein 1 Telomerase reverse transcriptase Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O00743 O14746 O15084 O60832 P20248 P24941 P54274 P78396 Q15554 Q5H9R7 Q6PI26 Q96AP0 Q9BSI4 Q9BUR4 Q9H611 Q9NPE3 Q9NUX5 Q9NX24 Q9NY12 Q9NYB0 Q9NZ71 Q9Y230 Q9Y265	ACD ANKRD28 C11orf23 C15orf20 C20orf41 CCN1 CCNA CCNA1 CCNA2 CDK2 CDKN2 DKC1 DRIP5 EST2 GAR1 INO80H INO80J KIAA0379 KIAA1088 KIAA1558 NHL NHP2 NMP238 NOLA1 NOLA2 NOLA3 NOLA4 NOP10 PIF1 PIN2 PIP1 POT1 PP6R3 PPP6 PPP6C PPP6R3 PTOP RAP1 RTEL1 RUVBL1 RUVBL2 SAPL SAPS3 SHQ1 TCAB1 TCS1 TERF1 TERF2 TERF2IP TERT TIN2 TINF2 TINT1 TIP48 TIP49 TIP49A TIP49B TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TRT WDR79 WRAP53	Homo sapiens (human)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	ATP-dependent DNA/RNA helicase DHX36 ATP-dependent RNA helicase A Interferon regulatory factor 7 Myeloid differentiation primary response protein MyD88 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P19838 Q00653 Q04206 Q08211 Q92985 Q99836 Q9H2U1	DDX36 DDX9 DHX36 DHX9 IRF7 KIAA1488 LKP LYT10 MLEL1 MYD88 NDH2 NFKB1 NFKB2 NFKB3 RELA RHAU	Homo sapiens (human)

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