GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **526 - 550** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
NOSTRIN mediated eNOS trafficking	Actin nucleation-promoting factor WASL Caveolin-1 Dynamin-2 Nitric oxide synthase 3 Nostrin	O00401 P29474 P50570 Q03135 Q8IVI9	CAV CAV1 DNM2 DYN2 NOS3 NOSTRIN WASL	Homo sapiens (human)
Aggrephagy	ADP-ribosylation factor-like protein 13B Centrin-1 Cystic fibrosis transmembrane conductance regulator Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 ubiquitin-protein ligase parkin Heat shock factor protein 1 Heat shock protein HSP 90-alpha Histone deacetylase 6 Intraflagellar transport protein 88 homolog Parkinson disease protein 7 Pericentrin Polyubiquitin-B Polyubiquitin-C Transitional endoplasmic reticulum ATPase Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14576 O43237 O60260 O95613 P07900 P0CG47 P0CG48 P13569 P55072 P61088 P62979 P62987 P63167 Q00613 Q12798 Q13099 Q13404 Q13409 Q14204 Q3SXY8 Q96FJ2 Q99497 Q9UBN7 Q9Y6G9	ABCC7 ARL13B ARL2L1 BLU CEN1 CETN CETN1 CFTR CROC1 DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 HDAC6 HDLC1 HEL-220 HEL-S-70 HSF1 HSP90A HSP90AA1 HSPC1 HSPCA HSTF1 IFT88 KIAA0325 KIAA0402 KIAA0901 LIC2 PARK2 PARK7 PCNT PCNT2 PRKN RPS27A TG737 TTC10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2N UBE2V UBE2V1 UEV1 VCP	Homo sapiens (human)
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Protein-tyrosine kinase 6	P11802 P24385 P24864 P24941 P46527 Q13882	BCL1 BRK CCND1 CCNE CCNE1 CDK2 CDK4 CDKN1B CDKN2 KIP1 PRAD1 PTK6 p27	Homo sapiens (human)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	GTPase HRas GTPase NRas Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O00459 O60674 P01111 P01112 P06239 P06241 P07947 P07948 P10721 P27986 P40763 P42224 P42229 P42336 P51692 Q07889 Q92569	APRF FYN GRB1 HRAS HRAS1 JAK2 JTK8 KIT LCK LYN NRAS PIK3CA PIK3R1 PIK3R2 PIK3R3 SCFR SOS1 STAT1 STAT3 STAT5 STAT5A STAT5B YES YES1	Homo sapiens (human)
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Cathepsin K Collagen alpha-1(IX) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-2(IX) chain Collagen alpha-3(IX) chain Collagenase 3 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 Disintegrin and metalloproteinase domain-containing protein 9 Furin Interstitial collagenase Macrophage metalloelastase Matrilysin Matrix metalloproteinase-14 Matrix metalloproteinase-15 Matrix metalloproteinase-19 Matrix metalloproteinase-20 Matrix metalloproteinase-9 Neutrophil collagenase Neutrophil elastase Procathepsin L Stromelysin-1 Stromelysin-2 Stromelysin-3 Transmembrane protease serine 6 Trypsin-2	O14672 O60882 P03956 P07339 P07478 P07711 P07858 P08246 P08253 P08254 P09237 P09238 P09958 P14780 P20849 P22894 P24347 P39059 P39060 P39900 P43235 P45452 P50281 P51511 P78536 Q05707 Q07092 Q13443 Q14050 Q14055 Q14993 Q5TAT6 Q86Y22 Q8IU80 Q8IUZ5 Q96A83 Q99542 Q99715 Q9BXS0 Q9UMD9	ADAM10 ADAM17 ADAM9 AGXT2L2 BP180 BPAG2 CLG CLG1 CLG4A CLG4B COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL23A1 COL25A1 COL26A1 COL9A1 COL9A2 COL9A3 CPSB CPSD CSVP CTSB CTSD CTSK CTSL CTSL1 CTSO CTSO2 ELA2 ELANE EMID2 EMU2 FUR FURIN HME KIAA0021 KUZ MADM MCMP MDC9 MLTNG MMP1 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP18 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 MPSL1 PACE PCSK3 PHYKPL PRSS2 PUMP1 RASI STMY1 STMY2 STMY3 TACE TMPRSS6 TRY2 TRYP2 UND	Homo sapiens (human)
MicroRNA (miRNA) biogenesis	DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Endoribonuclease Dicer Exportin-5 GTP-binding nuclear protein Ran Interferon-inducible double-stranded RNA-dependent protein kinase activator A Microprocessor complex subunit DGCR8 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 RISC-loading complex subunit TARBP2 RNA 5'-monophosphate methyltransferase Ribonuclease 3	O15514 O75569 P19387 P19388 P24928 P30876 P36954 P52434 P52435 P53803 P61218 P62487 P62826 P62875 Q15633 Q7Z5W3 Q8WYQ5 Q9H9G7 Q9HAV4 Q9HCK5 Q9NRR4 Q9UKV8 Q9UL18 Q9UPY3	AGO1 AGO2 AGO3 AGO4 ARA24 BCDIN3D C22orf12 DGCR8 DGCRK6 DICER DICER1 DROSHA EIF2C1 EIF2C2 EIF2C3 EIF2C4 HERNA KIAA0928 KIAA1291 KIAA1567 PACT POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PRKRA RAN RANBP21 RAX RN3 RNASE3L RNASEN RPB7 TARBP2 TRBP XPO5	Homo sapiens (human)
Role of LAT2/NTAL/LAB on calcium mobilization	3-phosphoinositide-dependent protein kinase 1 GRB2-associated-binding protein 2 IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Linker for activation of T-cells family member 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Son of sevenless homolog 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O00459 O15530 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P23083 P27986 P42336 P42338 P43405 P80748 Q07889 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9GZY6 Q9UQC2	FYN GAB2 GRB1 IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 JTK8 KIAA0571 LAB LAT2 LYN NTAL PDK1 PDPK1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 SOS1 SYK V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 WBS15 WBSCR15 WBSCR5	Homo sapiens (human)
phospho-PLA2 pathway	Cytosolic phospholipase A2 Mitogen-activated protein kinase 1	P28482 P47712	CPLA2 ERK2 MAPK1 PLA2G4 PLA2G4A PRKM1 PRKM2	Homo sapiens (human)
Signaling by kinase domain mutants of KIT	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Histidine catabolism	Carnosine N-methyltransferase Carnosine synthase 1 Formimidoyltransferase-cyclodeaminase Histamine N-methyltransferase Histidine ammonia-lyase Histidine decarboxylase Probable imidazolonepropionase Urocanate hydratase	A5YM72 O95954 P19113 P42357 P50135 Q8N4J0 Q96N76 Q96NU7	AMDHD1 ATPGD1 C9orf41 CARNMT1 CARNS1 FTCD HAL HDC HIS HNMT KIAA1394 UROC1	Homo sapiens (human)
Signaling by FGFR2 IIIa TM	DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 2 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2	O15514 P05230 P09038 P13984 P19387 P19388 P21802 P24928 P30876 P35269 P36954 P52298 P52434 P52435 P53803 P61218 P62487 P62875 Q09161	BEK CBP20 CBP80 FGF1 FGF2 FGFA FGFB FGFR2 GTF2F1 GTF2F2 KGFR KSAM NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RPB7	Homo sapiens (human)
Regulation of CDH11 gene transcription	Class E basic helix-loop-helix protein 22 Forkhead box protein F1 Hairy/enhancer-of-split related with YRPW motif-like protein Homeobox protein Hox-C8 Interleukin enhancer-binding factor 3 PR domain zinc finger protein 8 Transcription factor Sp1 Zinc finger E-box-binding homeobox 2 Zinc finger protein SNAI1	O60315 O95863 P08047 P31273 Q12906 Q12946 Q8NFJ8 Q9NQ87 Q9NQV8	BHLHB33 BHLHB5 BHLHE22 DRBF FKHL5 FOXF1 FREAC1 HEYL HOX3A HOXC8 HRT3 ILF3 KIAA0569 MPHOSPH4 NF90 PFM5 PRDM8 SIP1 SNAH SNAI1 SP1 TNRC20 TSFP1 ZEB2 ZFHX1B ZFX1B	Homo sapiens (human)
Biosynthesis of maresin-like SPMs	Cytochrome P450 1A2 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 2E1 Cytochrome P450 3A4	P05177 P05181 P08684 P10632 P10635 P11712	CYP1A2 CYP2C10 CYP2C8 CYP2C9 CYP2D6 CYP2DL1 CYP2E CYP2E1 CYP3A3 CYP3A4	Homo sapiens (human)
Defective visual phototransduction due to OPN1LW loss of function	Long-wave-sensitive opsin 1	P04000	OPN1LW RCP	Homo sapiens (human)
MET activates STAT3	Hepatocyte growth factor receptor Hepatocyte growth factor Signal transducer and activator of transcription 3	P08581 P14210 P40763	APRF HGF HPTA MET STAT3	Homo sapiens (human)
EGFR Transactivation by Gastrin	Epidermal growth factor receptor GTPase HRas GTPase NRas Proheparin-binding EGF-like growth factor Protein kinase C alpha type Son of sevenless homolog 1 Stromelysin-1	P00533 P01111 P01112 P08254 P17252 Q07889 Q99075	DTR DTS EGFR ERBB ERBB1 HBEGF HEGFL HER1 HRAS HRAS1 MMP3 NRAS PKCA PRKACA PRKCA SOS1 STMY1	Homo sapiens (human)
Activation of NOXA and translocation to mitochondria	Cellular tumor antigen p53 Phorbol-12-myristate-13-acetate-induced protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1	P04637 Q01094 Q13794 Q14186 Q14188	DP1 DP2 E2F1 NOXA P53 PMAIP1 RBBP3 TFDP1 TFDP2 TP53	Homo sapiens (human)
Inactivation of CSF3 (G-CSF) signaling	Cullin-5 Elongin-B Elongin-C Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Non-receptor tyrosine-protein kinase TYK2 Polyubiquitin-B Polyubiquitin-C RING-box protein 2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14543 O15524 O60674 P07948 P08631 P09919 P0CG47 P0CG48 P23458 P29597 P40763 P42224 P42229 P43405 P51668 P51692 P61077 P62837 P62979 P62987 Q15369 Q15370 Q93034 Q99062 Q9UBF6	APRF C17orf33 CIS3 CSF3 CSF3R CUL5 ELOB ELOC GCSF GCSFR HCK JAK1 JAK1A JAK1B JAK2 JTK8 LYN PUBC1 RBX2 RNF7 ROC2 RPS27A SAG SFT SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TCEB1 TCEB2 TIP3 TYK2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 VACM1	Homo sapiens (human)
mRNA Capping	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Transcription elongation factor SPT5 mRNA cap guanine-N7 methyltransferase mRNA-capping enzyme	O00267 O15514 O43148 O60942 P13984 P18074 P19387 P19388 P19447 P24928 P30876 P32780 P35269 P36954 P50613 P51946 P51948 P52298 P52434 P52435 P53803 P61218 P62487 P62875 Q09161 Q13888 Q13889 Q6ZYL4 Q92759	BTF2 BTF2P44 C6orf175 CAK CAK1 CAP1A CAP35 CBP20 CBP80 CCNH CDK7 CDKN7 ERCC2 ERCC3 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA0398 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RNF66 RNGTT RNMT RPB7 SPT5 SPT5H STK1 SUPT5H TTDA XPB XPBC XPD XPDC	Homo sapiens (human)
RIP-mediated NFkB activation via ZBP1	ATP-dependent RNA helicase A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 1 NF-kappa-B inhibitor-interacting Ras-like protein 2 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 Toll-like receptor 3 Transcription factor p65 Z-DNA-binding protein 1	O14920 O15111 O15455 P19838 P25963 Q00653 Q04206 Q08211 Q13546 Q15653 Q8IUC6 Q99836 Q9H171 Q9NYR9 Q9NYS0 Q9Y572 Q9Y6K9	C20orf183 CHUK DDX9 DHX9 DLM1 FIP3 IKBA IKBB IKBKB IKBKG IKKA IKKB KBRAS1 KBRAS2 LKP LYT10 MAD3 MYD88 NDH2 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA NFKBIB NKIRAS1 NKIRAS2 PRVTIRB RELA RIP RIP1 RIP3 RIPK1 RIPK3 TCF16 TICAM1 TLR3 TRIF TRIP9 ZBP1	Homo sapiens (human)
Sodium/Calcium exchangers	Calmodulin-1 Mitochondrial sodium/calcium exchanger protein Sodium/calcium exchanger 1 Sodium/calcium exchanger 2 Sodium/calcium exchanger 3 Sodium/potassium/calcium exchanger 1 Sodium/potassium/calcium exchanger 2 Sodium/potassium/calcium exchanger 3 Sodium/potassium/calcium exchanger 4 Sodium/potassium/calcium exchanger 5 Sorcin	O60721 P0DP23 P30626 P32418 P57103 Q6J4K2 Q71RS6 Q8NFF2 Q9HC58 Q9UI40 Q9UPR5	CALM CALM1 CAM CAM1 CNC JSX KIAA0702 KIAA1087 NCKX1 NCKX2 NCKX3 NCKX4 NCKX5 NCKX6 NCLX NCX1 NCX2 NCX3 SLC24A1 SLC24A2 SLC24A3 SLC24A4 SLC24A5 SLC24A6 SLC8A1 SLC8A2 SLC8A3 SLC8B1 SRI	Homo sapiens (human)
Regulation of the apoptosome activity	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP Methylthioribulose-1-phosphate dehydratase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Uveal autoantigen with coiled-coil domains and ankyrin repeats	O14727 P27361 P28482 P55211 P98170 P99999 Q96GX9 Q9BZF9 Q9NQS1 Q9NR28 Q9Y2G2	APAF1 API3 APIP AVEN BIRC4 CARD8 CASP9 CYC CYCS DACAR DIABLO ERK1 ERK2 IAP3 KIAA0413 KIAA0955 KIAA1561 MAPK1 MAPK3 MCH6 NDPP1 PRKM1 PRKM2 PRKM3 SMAC UACA XIAP	Homo sapiens (human)
COPI-mediated anterograde transport	ADP-ribosylation factor 1 ADP-ribosylation factor 3 ADP-ribosylation factor 4 ADP-ribosylation factor 5 ADP-ribosylation factor GTPase-activating protein 1 ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 Actin-related protein 10 Alpha-centractin Alpha-soluble NSF attachment protein Ankyrin-1 Ankyrin-2 Ankyrin-3 BET1 homolog BET1-like protein Beta-soluble NSF attachment protein CD59 glycoprotein Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma-1 Coatomer subunit gamma-2 Coatomer subunit zeta-1 Coatomer subunit zeta-2 Complement decay-accelerating factor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic ER lumen protein-retaining receptor 1 ER lumen protein-retaining receptor 2 ER lumen protein-retaining receptor 3 F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Folate receptor alpha Gamma-soluble NSF attachment protein General vesicular transport factor p115 Golgi SNAP receptor complex member 1 Golgi SNAP receptor complex member 2 Golgi reassembly-stacking protein 1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Golgin subfamily A member 2 Golgin subfamily B member 1 Insulin Ras-related protein Rab-1A Ras-related protein Rab-1B Spectrin alpha chain, erythrocytic 1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, erythrocytic Spectrin beta chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 2 Spectrin beta chain, non-erythrocytic 4 Spectrin beta chain, non-erythrocytic 5 Synaptobrevin homolog YKT6 Syntaxin-5 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Transmembrane emp24 domain-containing protein 3 Transmembrane emp24 domain-containing protein 7 Transmembrane emp24 domain-containing protein 9 Transmembrane protein 115 Vesicle-fusing ATPase	O00399 O14576 O14579 O14653 O15020 O15155 O15498 O43237 O43731 O60763 O75935 O95249 P01308 P02549 P08174 P11277 P13987 P15328 P16157 P18085 P24390 P33947 P35606 P46459 P47755 P47756 P48444 P49755 P52907 P53618 P53621 P54920 P61163 P61204 P61923 P62820 P63167 P83436 P84077 P84085 Q01082 Q01484 Q08379 Q12893 Q12955 Q13190 Q13409 Q13561 Q13813 Q14203 Q14204 Q14746 Q14789 Q15363 Q8N6H7 Q8N6T3 Q8WTW3 Q92538 Q96FJ2 Q96JB2 Q96KX2 Q96MW5 Q99747 Q9BQQ3 Q9BTE1 Q9BVK6 Q9H0U4 Q9H115 Q9H254 Q9H9E3 Q9NP61 Q9NRC6 Q9NYM9 Q9NZ32 Q9P299 Q9UBF2 Q9UJW0 Q9UP83 Q9Y2V7 Q9Y3B3 Q9Y3Q3 Q9Y678 Q9Y6G9	ACTR10 ACTR11 ACTR1A ANK ANK1 ANK2 ANK3 ANKB ARCN1 ARF1 ARF1GAP ARF2 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 ARP10 ARP11 BET1 BET1L BSPECV C15orf22 CAPAA3 CAPZA1 CAPZA2 CAPZA3 CAPZB CD55 CD59 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 COPA COPB COPB1 COPB2 COPD COPE COPG COPG1 COPG2 COPZ COPZ1 COPZ2 CR CTRN1 DAF DCTN1 DCTN2 DCTN22 DCTN3 DCTN4 DCTN5 DCTN50 DCTN6 DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ERD2.1 ERD2.2 ERD23 FOLR FOLR1 GBF1 GOLGA2 GOLGB1 GOLPH5 GOLTC1 GORASP1 GOSR1 GOSR2 GP25L2 GRASP65 GS15 GS27 GS28 GSG3 GTC90 HDLC1 HUBSPECV HUSPECV INS KDELR1 KDELR2 KDELR3 KIAA0248 KIAA0302 KIAA0325 KIAA1134 KIAA1381 KIAA1642 LDLB LDLC LIC2 MIC11 MIN1 MIN2 MIN3 MSK21 NAPA NAPB NAPG NEAS NSF PL6 RAB1 RAB1A RAB1B RNP24 SCA5 SEC34 SNAPA SNAPB SNAPG SPTA SPTA1 SPTA2 SPTAN1 SPTB SPTB1 SPTB2 SPTBN1 SPTBN2 SPTBN3 SPTBN4 SPTBN5 STX5 STX5A TMED10 TMED2 TMED3 TMED7 TMED9 TMEM115 TMP21 USO1 VDP WS3 YKT6 ZNF289	Homo sapiens (human)
Post-chaperonin tubulin folding pathway	ADP-ribosylation factor-like protein 2 Putative tubulin-like protein alpha-4B Tubulin alpha chain-like 3 Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3C chain Tubulin alpha-3D chain Tubulin alpha-3E chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta-1 chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin beta-6 chain Tubulin-folding cofactor B Tubulin-specific chaperone A Tubulin-specific chaperone C Tubulin-specific chaperone D Tubulin-specific chaperone E	A6NHL2 O75347 P04350 P0DPH7 P0DPH8 P36404 P68363 P68366 P68371 Q13509 Q13885 Q15813 Q15814 Q6PEY2 Q71U36 Q99426 Q9BQE3 Q9BTW9 Q9BUF5 Q9BVA1 Q9H4B7 Q9H853 Q9NY65	ARL2 CG22 CKAP1 KIAA0988 SSD1 TBCA TBCB TBCC TBCD TBCE TFCD TUBA1 TUBA1A TUBA1B TUBA1C TUBA2 TUBA3 TUBA3C TUBA3D TUBA3E TUBA4 TUBA4A TUBA4B TUBA6 TUBA8 TUBAL2 TUBAL3 TUBB1 TUBB2 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4A TUBB4B TUBB5 TUBB6	Homo sapiens (human)
Acetylcholine regulates insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Muscarinic acetylcholine receptor M3 Myristoylated alanine-rich C-kinase substrate Protein kinase C alpha type	O95837 P17252 P20309 P29966 P29992 P30679 P50148 Q00722 Q01970 Q9NQ66	CHRM3 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ KIAA0581 MACS MARCKS PKCA PLCB1 PLCB2 PLCB3 PRKACA PRKCA PRKCSL	Homo sapiens (human)

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