GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **576 - 600** of **2074** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
EML4 and NUDC in mitotic spindle formation	Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 20 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Echinoderm microtubule-associated protein-like 4 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 SKA complex subunit 1 Serine/threonine-protein kinase Nek6 Serine/threonine-protein kinase Nek7 Serine/threonine-protein kinase Nek9 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 2 ZW10 interactor	O00139 O14576 O14777 O14980 O15392 O43237 O43264 O43683 O43684 O60566 O75122 O95229 P30153 P30154 P30622 P36873 P42677 P43034 P46060 P49450 P49454 P49792 P50748 P53350 P55735 P57740 P62714 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14738 Q15172 Q15173 Q15691 Q16537 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q8N0S6 Q8N2Z9 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NI77 Q8TD19 Q8TDX7 Q8WUM0 Q8WVK7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96EA4 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9HC35 Q9HC98 Q9NQS7 Q9NSP4 Q9NXR1 Q9P258 Q9Y266 Q9Y6D9 Q9Y6G9	AHCTF1 AIK2 AIM1 AIRK2 API4 APITD1 ARK2 AURKB B9D2 BIRC5 BUB1 BUB1B BUB1L BUB3 BUBR1 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C2orf2 C6orf139 CASC5 CCDC99 CDC20 CDCA1 CDCA8 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CYLN1 D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ELYS EMAPL4 EML4 EOPA ERCC6L FAAP16 FAM33A FSHPRH1 HDLC1 HEC HEC1 IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0097 KIAA0166 KIAA0197 KIAA0325 KIAA0622 KIAA0627 KIAA1361 KIAA1470 KIAA1570 KIAA1835 KIAA1995 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MCM21R MDCR MDS MHF1 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MPS1 NDC80 NDE1 NDEL1 NEK6 NEK7 NEK8 NEK9 NERCC NRIF3 NSL1 NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PESCRG3 PICH PLK PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RANBP2 RANGAP1 RCC2 ROD RPS27 RSN SD SEC13 SEC13A SEC13L1 SEC13R SGO1 SGO2 SGOL1 SGOL2 SKA1 SKA2 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STK1 STK12 STK5 TAOK1 TD60 TMBS62 TXBP181 XPO1 ZW10 ZWILCH ZWINT	Homo sapiens (human)
EPH-Ephrin signaling	Ephrin type-A receptor 10 Ephrin type-A receptor 1 Ephrin type-A receptor 2 Ephrin type-A receptor 3 Ephrin type-A receptor 4 Ephrin type-A receptor 5 Ephrin type-A receptor 6 Ephrin type-A receptor 7 Ephrin type-A receptor 8 Ephrin type-B receptor 1 Ephrin type-B receptor 2 Ephrin type-B receptor 3 Ephrin type-B receptor 4 Ephrin type-B receptor 6 Ephrin-A1 Ephrin-A2 Ephrin-A3 Ephrin-A4 Ephrin-A5 Ephrin-B1 Ephrin-B2 Ephrin-B3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O15197 O43921 P06241 P07947 P07948 P20827 P21709 P29317 P29320 P29322 P29323 P52797 P52798 P52799 P52803 P54753 P54756 P54760 P54762 P54764 P98172 Q15375 Q15768 Q5JZY3 Q9UF33	BSK DRT ECK EEK EFL2 EFL3 EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EHK1 EHK2 EHK3 ELK EPH EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPHT EPHT1 EPHT2 EPHT3 EPLG1 EPLG2 EPLG3 EPLG4 EPLG5 EPLG6 EPLG7 EPLG8 EPTH3 ERK ETK ETK1 ETK2 FYN HEK HEK11 HEK12 HEK2 HEK3 HEK5 HEK6 HEK7 HEK8 HTK HTKL JTK8 KIAA1459 LERK1 LERK2 LERK3 LERK4 LERK5 LERK6 LERK7 LERK8 LYN MYK1 NET SEK TNFAIP4 TYRO1 TYRO11 TYRO4 TYRO5 TYRO6 YES YES1	Homo sapiens (human)
EPH-ephrin mediated repulsion of cells	72 kDa type IV collagenase AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disintegrin and metalloproteinase domain-containing protein 10 Dynamin-1 Ephrin type-A receptor 10 Ephrin type-A receptor 1 Ephrin type-A receptor 2 Ephrin type-A receptor 3 Ephrin type-A receptor 4 Ephrin type-A receptor 5 Ephrin type-A receptor 6 Ephrin type-A receptor 7 Ephrin type-A receptor 8 Ephrin type-B receptor 1 Ephrin type-B receptor 2 Ephrin type-B receptor 3 Ephrin type-B receptor 4 Ephrin type-B receptor 6 Ephrin-A1 Ephrin-A2 Ephrin-A3 Ephrin-A4 Ephrin-A5 Ephrin-B1 Ephrin-B2 Ephrin-B3 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Matrix metalloproteinase-9 Nicastrin Presenilin-1 Presenilin-2 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor TIAM1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O14672 O15197 O43921 O94973 O95782 P06241 P07947 P07948 P08253 P09496 P09497 P14780 P20827 P21709 P29317 P29320 P29322 P29323 P49768 P49810 P52735 P52797 P52798 P52799 P52803 P53675 P53680 P54753 P54756 P54760 P54762 P54764 P63000 P63010 P98172 Q00610 Q05193 Q13009 Q15375 Q15768 Q5JZY3 Q8WW43 Q92542 Q96BI3 Q96CW1 Q9NZ42 Q9UF33 Q9UKW4	AD3 AD4 ADAM10 ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APH1A APH1B BSK CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLG4A CLG4B CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DNM DNM1 DRT ECK EEK EFL2 EFL3 EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EHK1 EHK2 EHK3 ELK EPH EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPHT EPHT1 EPHT2 EPHT3 EPLG1 EPLG2 EPLG3 EPLG4 EPLG5 EPLG6 EPLG7 EPLG8 EPTH3 ERK ETK ETK1 ETK2 FYN HEK HEK11 HEK12 HEK2 HEK3 HEK5 HEK6 HEK7 HEK8 HIP9 HTK HTKL HYPJ JTK8 KIAA0034 KIAA0109 KIAA0253 KIAA0899 KIAA1459 KUZ LERK1 LERK2 LERK3 LERK4 LERK5 LERK6 LERK7 LERK8 LYN MADM MMP2 MMP9 MYK1 NCSTN NET PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RAC1 SEK STM2 TC25 TIAM1 TNFAIP4 TYRO1 TYRO11 TYRO4 TYRO5 TYRO6 VAV2 VAV3 YES YES1	Homo sapiens (human)
EPHA-mediated growth cone collapse	Ephexin-1 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O14950 O75116 P06241 P07947 P07948 P24844 P35579 P35580 P35749 P60660 P61586 Q13464 Q7Z406 Q8N5V2	ARH12 ARHA FYN JTK8 KIAA0619 KIAA0866 KIAA2034 LYN MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYRL2 NGEF RHO12 RHOA ROCK1 ROCK2 YES YES1	Homo sapiens (human)
EPHB-mediated forward signaling	Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Cofilin-1 Focal adhesion kinase 1 GTPase HRas Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Intersectin-1 Kalirin LIM domain kinase 1 LIM domain kinase 2 Ras GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor TIAM1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Serine/threonine-protein kinase PAK 1 Syndecan-2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O00401 O15143 O15144 O15145 O15511 O60229 O75116 P01112 P06241 P07947 P07948 P20936 P23528 P34741 P53667 P53671 P59998 P60709 P60953 P61158 P61160 P61586 P63000 P63261 Q05397 Q05586 Q13009 Q13153 Q13224 Q13464 Q15811 Q8N1W1 Q92747	ACTB ACTG ACTG1 ACTR2 ACTR3 ARC16 ARC20 ARC21 ARC34 ARC41 ARH12 ARHA ARHGEF28 ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CFL CFL1 DUET DUO FAK FAK1 FYN GAP GRIN1 GRIN2B HAPIP HRAS HRAS1 HSPG1 ITSN ITSN1 JTK8 KALRN KIAA0619 KIAA1998 LIMK LIMK1 LIMK2 LYN NMDAR1 NMDAR2B PAK1 PTK2 RAC1 RASA RASA1 RGNEF RHO12 RHOA ROCK1 ROCK2 SDC2 SH3D1A SOP2L TC25 TIAM1 TRAD WASL YES YES1	Homo sapiens (human)
ER Quality Control Compartment (ERQC)	Derlin-2 E3 ubiquitin-protein ligase AMFR E3 ubiquitin-protein ligase MARCHF6 E3 ubiquitin-protein ligase RNF103 E3 ubiquitin-protein ligase RNF139 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 E3 ubiquitin-protein ligase TRIM13 E3 ubiquitin-protein ligase synoviolin ER degradation-enhancing alpha-mannosidase-like protein 1 ER degradation-enhancing alpha-mannosidase-like protein 2 ER degradation-enhancing alpha-mannosidase-like protein 3 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Polyubiquitin-B Polyubiquitin-C Protein OS-9 Protein sel-1 homolog 1 UDP-glucose UDP-glucose Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00237 O60337 O60858 P0CG47 P0CG48 P62979 P62987 Q13438 Q86TM6 Q8WU17 Q92611 Q96GF1 Q99942 Q9BV94 Q9BZQ6 Q9GZP9 Q9NYU1 Q9NYU2 Q9UBV2 Q9UKM7 Q9UKV5	AMFR C1orf22 C20orf31 C20orf49 DER2 DERL2 EDEM EDEM1 EDEM2 EDEM3 FLANA G16 GT HRD1 KIAA0212 KIAA0597 KIAA1810 LEU5 MAN1B1 MARCH6 MARCHF6 NG2 OS9 RFP2 RMA1 RNF103 RNF139 RNF176 RNF185 RNF45 RNF5 RNF77 RPS27A SEL1L SYVN1 TEB4 TRC8 TRIM13 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UGCGL1 UGCGL2 UGGT UGGT1 UGGT2 UGT1 UGT2 UGTR ZFP103	Homo sapiens (human)	G70323CJ G93575MM
ER-Phagosome pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Antigen peptide transporter 1 Antigen peptide transporter 2 Beta-2-microglobulin Calreticulin Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein S100-A1 Protein S100-A8 Protein S100-A9 Protein disulfide-isomerase A3 Protein transport protein Sec61 subunit alpha isoform 1 Protein transport protein Sec61 subunit alpha isoform 2 Protein transport protein Sec61 subunit beta Protein transport protein Sec61 subunit gamma Putative HLA class I histocompatibility antigen, alpha chain H Synaptosomal-associated protein 23 Syntaxin-4 Tapasin Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 8 Vesicle-trafficking protein SEC22b	O00161 O00206 O00231 O00232 O00487 O14818 O14920 O15111 O15533 O43242 O60603 O75396 P01889 P01893 P02671 P02675 P02679 P04439 P05109 P06702 P08571 P09429 P0CG47 P0CG48 P10321 P13747 P16671 P17693 P17980 P20618 P23297 P25786 P25787 P25788 P25789 P26623 P27797 P28066 P28070 P28072 P28074 P30101 P30511 P30690 P35998 P43686 P48556 P49720 P49721 P51665 P58753 P60059 P60468 P60896 P60900 P61619 P61769 P62191 P62195 P62333 P62979 P62987 Q03518 Q03519 Q06187 Q12846 Q13200 Q15008 Q15399 Q15836 Q16186 Q99436 Q99460 Q99836 Q9BV40 Q9H9S3 Q9UNM6 Q9Y2C9 Q9Y6K9 Q9Y6Y9	ABCB2 ABCB3 ADRM1 AGMX1 ATK B2M BPK BTK C7orf76 CAGA CAGB CALR CD14 CD36 CFAG CHUK CRTC DSS1 ERP57 ERP60 ESOP1 FGA FGB FGG FIP3 GP110 GP3B GP4 GRP58 HC2 HC3 HC8 HC9 HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HMG1 HMGB1 HSPC IKBKB IKBKG IKKA IKKB KIAA0012 KIAA0107 LMPX LMPY LY96 MAL MB1 MD2 MIP224 MOV34L MRP14 MRP8 MSS1 MYD88 NEMO NGS17 NU PDIA3 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSF1 PSF2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RING11 RING4 RPS27A S100A S100A1 S100A8 S100A9 SEC22B SEC22L1 SEC61A SEC61A1 SEC61A2 SEC61B SEC61G SEM1 SHFDG1 SHFM1 SNAP23 STX4 STX4A SUG1 SUG2 SYB3 TAP1 TAP2 TAPA TAPBP TBP1 TBP7 TCF16 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VAMP3 VAMP8 X Y Y1 Y3 Z mip porB	Homo sapiens (human)
ERBB2 Activates PTK6 Signaling	Epidermal growth factor receptor Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein-tyrosine kinase 6 Receptor tyrosine-protein kinase erbB-2	O14511 O14944 P00533 P01133 P04626 P35070 P56975 Q02297 Q13882 Q8WWG1 Q99075	BRK BTC DTR DTS EGF EGFR ERBB ERBB1 ERBB2 EREG GGF HBEGF HEGFL HER1 HER2 HGL HRGA MLN19 NDF NEU NGL NRG1 NRG2 NRG3 NRG4 NTAK PTK6 SMDF	Homo sapiens (human)
ERBB2 Regulates Cell Motility	Epidermal growth factor receptor Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein MEMO1 Protein diaphanous homolog 1 Receptor tyrosine-protein kinase erbB-2 Transforming protein RhoA	O14511 O14944 O60610 P00533 P01133 P04626 P35070 P56975 P61586 Q02297 Q8WWG1 Q99075 Q9Y316	ARH12 ARHA BTC C2orf4 DIAP1 DIAPH1 DTR DTS EGF EGFR ERBB ERBB1 ERBB2 EREG GGF HBEGF HEGFL HER1 HER2 HGL HRGA MEMO MEMO1 MLN19 NDF NEU NGL NRG1 NRG2 NRG3 NRG4 NS5ATP7 NTAK RHO12 RHOA SMDF	Homo sapiens (human)
ERK/MAPK targets	ETS domain-containing protein Elk-1 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Myocyte-specific enhancer factor 2A Myocyte-specific enhancer factor 2C Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-5 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O75582 P19419 P27361 P28482 P30153 P30154 P51812 P62714 P67775 Q02078 Q06413 Q13164 Q14738 Q15349 Q15418 Q15759 Q16539	BMK1 CSBP CSBP1 CSBP2 CSPB1 ELK1 ERK1 ERK2 ERK5 ISPK1 MAPK1 MAPK11 MAPK14 MAPK3 MAPK7 MAPKAPK1A MAPKAPK1B MAPKAPK1C MEF2 MEF2A MEF2C MSK1 MXI2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKM1 PRKM11 PRKM2 PRKM3 PRKM7 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA5 RSK1 RSK2 RSK3 SAPK2 SAPK2A SAPK2B	Homo sapiens (human)
ERKs are inactivated	Dual specificity protein phosphatase 3 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Serine/threonine-protein kinase VRK3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	P27361 P28482 P30153 P30154 P51452 P62714 P67775 Q13115 Q13164 Q14738 Q16828 Q16829 Q8IV63	BMK1 DUSP3 DUSP4 DUSP6 DUSP7 ERK1 ERK2 ERK5 MAPK1 MAPK3 MAPK7 MKP2 MKP3 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKM1 PRKM2 PRKM3 PRKM7 PYST1 PYST2 VH2 VHR VRK3	Homo sapiens (human)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Peptidyl-prolyl cis-trans isomerase D Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP5 Prostaglandin E synthase 3 Serine/threonine-protein phosphatase 5	P03372 P07900 P08238 P27361 P28482 P53041 Q02790 Q08752 Q13451 Q15185 Q92731	AIG6 CYP40 CYPD ERK1 ERK2 ESR ESR1 ESR2 ESTRB FKBP4 FKBP5 FKBP51 FKBP52 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB MAPK1 MAPK3 NR3A1 NR3A2 P23 PPID PPP5 PPP5C PRKM1 PRKM2 PRKM3 PTGES3 TEBP	Homo sapiens (human)
Early Phase of HIV Life Cycle	DNA ligase 1 Flap endonuclease 1 Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04618 P05919 P18858 P39748 P62937 P69723 P69726	CYPA FEN1 LIG1 PPIA RAD2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Effects of PIP2 hydrolysis	Diacylglycerol kinase alpha Diacylglycerol kinase beta Diacylglycerol kinase delta Diacylglycerol kinase epsilon Diacylglycerol kinase eta Diacylglycerol kinase gamma Diacylglycerol kinase iota Diacylglycerol kinase kappa Diacylglycerol kinase theta Diacylglycerol kinase zeta Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C theta type RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 Short transient receptor potential channel 3 Short transient receptor potential channel 6 Short transient receptor potential channel 7	O75912 O95267 P23743 P24723 P49619 P52429 P52824 Q02156 Q04759 Q05655 Q13507 Q13574 Q14571 Q14573 Q14643 Q16760 Q5KSL6 Q7LDG7 Q86XP1 Q9HCX4 Q9Y210 Q9Y6T7	CDC25L DAGK DAGK1 DAGK2 DAGK3 DAGK4 DAGK5 DAGK6 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKK DGKQ DGKZ INSP3R1 ITPR1 ITPR2 ITPR3 KIAA0145 KIAA0718 MCG7 PKCD PKCE PKCL PRKCD PRKCE PRKCH PRKCL PRKCQ PRKCT RASGRP RASGRP1 RASGRP2 TRP3 TRP6 TRP7 TRPC3 TRPC6 TRPC7	Homo sapiens (human)
Eicosanoid ligand-binding receptors	Oxoeicosanoid receptor 1	Q8TDS5	GPR170 OXER1 TG1019	Homo sapiens (human)
Eicosanoids	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Cytochrome P450 4A11 Cytochrome P450 4A22 Cytochrome P450 4B1 Cytochrome P450 4F11 Cytochrome P450 4F12 Cytochrome P450 4F2 Cytochrome P450 4F3 Cytochrome P450 4F8 Prostacyclin synthase Thromboxane-A synthase Ultra-long-chain fatty acid omega-hydroxylase	P13584 P24557 P78329 P98187 Q02928 Q08477 Q16647 Q5TCH4 Q6NT55 Q9HBI6 Q9HCS2 Q9UNU6	CYP12 CYP4A11 CYP4A2 CYP4A22 CYP4B1 CYP4F11 CYP4F12 CYP4F2 CYP4F22 CYP4F3 CYP4F8 CYP5 CYP5A1 CYP8 CYP8A1 CYP8B1 LTB4H PTGIS TBXAS1 TXAS	Homo sapiens (human)
Elastic fibre formation	Elastin Fibrillin-1 Fibrillin-2 Fibrillin-3 Fibulin-5 Furin Integrin alpha-5 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-6 Lysyl oxidase homolog 1 Lysyl oxidase homolog 2 Lysyl oxidase homolog 3 Lysyl oxidase homolog 4 Microfibrillar-associated protein 2 Microfibrillar-associated protein 5 Protein-lysine 6-oxidase	P05106 P05556 P06756 P08648 P09958 P15502 P18564 P28300 P35555 P35556 P55001 P58215 Q08397 Q13361 Q75N90 Q96JB6 Q9UBX5 Q9Y4K0	DANCE ELN FBLN5 FBN FBN1 FBN2 FBN3 FNRA FNRB FUR FURIN GP3A ITGA5 ITGAV ITGB1 ITGB3 ITGB6 KIAA1776 LOX LOXC LOXL LOXL1 LOXL2 LOXL3 LOXL4 MAGP1 MAGP2 MDF2 MFAP2 MFAP5 MSK12 MSK8 PACE PCSK3 VNRA VTNR	Homo sapiens (human)
Electric Transmission Across Gap Junctions	Gap junction alpha-10 protein Gap junction delta-2 protein Gap junction gamma-1 protein Pannexin-1 Pannexin-2	P36383 Q969M2 Q96RD6 Q96RD7 Q9UKL4	CX62 GJA10 GJA7 GJA9 GJC1 GJD2 MRS1 PANX1 PANX2	Homo sapiens (human)
Electron transport from NADPH to Ferredoxin	Adrenodoxin, mitochondrial Ferredoxin-2, mitochondrial NADPH	P10109 P22570 Q6P4F2	ADX ADXR FDX1 FDX1L FDX2 FDXR	Homo sapiens (human)
Elevation of cytosolic Ca2+ levels	Calcium release-activated calcium channel protein 1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 P2X purinoceptor 1 P2X purinoceptor 2 P2X purinoceptor 3 P2X purinoceptor 4 P2X purinoceptor 5 P2X purinoceptor 6 P2X purinoceptor 7 Protein orai-2 Short transient receptor potential channel 3 Short transient receptor potential channel 6 Short transient receptor potential channel 7 Stromal interaction molecule 1	O15547 P51575 P56373 Q13507 Q13586 Q14571 Q14573 Q14643 Q93086 Q96D31 Q96SN7 Q99571 Q99572 Q9HCX4 Q9UBL9 Q9Y210	C7orf19 CBCIP2 CRACM1 GOK INSP3R1 ITPR1 ITPR2 ITPR3 ORAI1 ORAI2 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 P2RXL1 P2X1 P2X2 P2X5 P2X5FL P2X6 STIM1 TMEM142A TMEM142B TRP3 TRP6 TRP7 TRPC3 TRPC6 TRPC7	Homo sapiens (human)
Endogenous sterols	24-hydroxycholesterol 7-alpha-hydroxylase Adrenodoxin, mitochondrial Aromatase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Bile acid receptor Cholesterol 24-hydroxylase Cholesterol side-chain cleavage enzyme, mitochondrial Cytochrome P450 11B1, mitochondrial Cytochrome P450 11B2, mitochondrial Cytochrome P450 1B1 Cytochrome P450 4V2 Cytochrome P450 7A1 Cytochrome P450 7B1 Ferredoxin-2, mitochondrial Lanosterol 14-alpha demethylase NADPH Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Pro-opiomelanocortin Retinoic acid receptor RXR-alpha Steroid 21-hydroxylase Sterol 26-hydroxylase, mitochondrial	A9YTQ3 O75881 P01189 P05108 P08686 P10109 P11511 P15538 P19099 P19793 P22570 P22680 P27540 P35869 Q02318 Q15596 Q15788 Q16678 Q16850 Q6P4F2 Q6ZWL3 Q96RI1 Q9HBZ2 Q9NYL5 Q9Y6A2	ADX ADXR AHR AHRR ARNT ARNT2 ARO1 BAR BHLHE1 BHLHE2 BHLHE74 BHLHE75 BHLHE76 BHLHE77 CYAR CYP11A CYP11A1 CYP11B1 CYP11B2 CYP19 CYP19A1 CYP1B1 CYP21 CYP21A2 CYP21B CYP27 CYP27A1 CYP39A1 CYP46 CYP46A1 CYP4V2 CYP51 CYP51A1 CYP7 CYP7A1 CYP7B1 FDX1 FDX1L FDX2 FDXR FXR HRR1 KIAA0307 KIAA1234 NCOA1 NCOA2 NR1H4 NR2B1 POMC RIP14 RXRA S11BH SRC1 SRC2 TIF2	Homo sapiens (human)
Endosomal Sorting Complex Required For Transport (ESCRT)	Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 5 Charged multivesicular body protein 6 Charged multivesicular body protein 7 Hepatocyte growth factor-regulated tyrosine kinase substrate Multivesicular body subunit 12A Multivesicular body subunit 12B Polyubiquitin-B Polyubiquitin-C Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Tumor susceptibility gene 101 protein Ubiquitin-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein sorting-associated protein 37A Vacuolar protein sorting-associated protein 37B Vacuolar protein sorting-associated protein 37C Vacuolar protein sorting-associated protein 37D Vacuolar protein sorting-associated protein 4A Vacuolar protein sorting-associated protein 4B Vacuolar protein sorting-associated protein VTA1 homolog Vacuolar protein-sorting-associated protein 25 Vacuolar protein-sorting-associated protein 36 Vacuolar-sorting protein SNF8	A5D8V6 O14964 O43633 O75351 O75886 P0CG47 P0CG48 P62979 P62987 Q86VN1 Q86XT2 Q8NEZ2 Q8WUX9 Q92783 Q96CF2 Q96EY5 Q96FZ7 Q96H20 Q99816 Q9BRG1 Q9BY43 Q9H444 Q9H7P6 Q9H9H4 Q9NP79 Q9NZ09 Q9NZZ3 Q9UK41 Q9UN37 Q9UQN3 Q9Y3E7	BC2 C13orf9 C14orf123 C20orf178 C6orf55 C9orf28 C9orf83 CFBP CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CHMP6 CHMP7 DERP9 EAP20 EAP30 EAP45 FAM125A FAM125B HBP HCRP1 HGS HRS MVB12A MVB12B NEDF PML39 RPS27A SHAX1 SHAX2 SHAX3 SKD1 SNF7DC2 SNF8 STAM STAM1 STAM2 TSG101 UBA52 UBA80 UBAP1 UBB UBC UBCEP1 UBCEP2 VPS20 VPS24 VPS25 VPS28 VPS36 VPS37A VPS37B VPS37C VPS37D VPS4 VPS42 VPS4A VPS4B VTA1 WBSCR24	Homo sapiens (human)
Endosomal/Vacuolar pathway	Beta-2-microglobulin Cathepsin L2 Cathepsin S HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Leucyl-cystinyl aminopeptidase Procathepsin L Putative HLA class I histocompatibility antigen, alpha chain H	O60911 P01889 P01893 P04439 P07711 P10321 P13747 P17693 P25774 P30511 P61769 Q9UIQ6	B2M CATL2 CTSL CTSL1 CTSL2 CTSS CTSU CTSV HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH LNPEP OTASE	Homo sapiens (human)
Energy dependent regulation of mTOR by LKB1-AMPK	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Calcium-binding protein 39-like Calcium-binding protein 39 GTP-binding protein Rheb Hamartin Neutral amino acid transporter 9 Protein phosphatase 1A Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR STE20-related kinase adapter protein alpha STE20-related kinase adapter protein beta Serine/threonine-protein kinase STK11 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Tuberin	O43504 O43741 P35813 P42345 P49815 P54619 P54646 Q0VGL1 Q13131 Q15382 Q15831 Q5VZM2 Q6IAA8 Q7L523 Q7RTN6 Q8N122 Q8NBW4 Q92574 Q9BVC4 Q9C0K7 Q9H9S4 Q9HB90 Q9NQL2 Q9UGI9 Q9UGJ0 Q9UHA4 Q9Y2Q5 Q9Y376 Q9Y478	ALS2CR2 AMPK AMPK1 AMPK2 AMPKG3 C11orf59 C7orf59 CAB39 CAB39L FRAP FRAP1 FRAP2 GBL HBXIP ILPIP KIAA0243 KIAA1303 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LKB1 LST8 LYK5 MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MO25 MTOR PDRO PJS PPM1A PPPM1A PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 STK11 STRAD STRADA STRADB TSC TSC1 TSC2 TSC4 URLC11 XIP	Homo sapiens (human)
Enhanced binding of GP1BA variant to VWF multimer:collagen	Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V von Willebrand factor	P04275 P07359 P13224 P14770 P40197	F8VWF GP1BA GP1BB GP5 GP9 VWF	Homo sapiens (human)

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