Regulation by c-FLIP
|
|
|
- APO2
- APO2L
- APT1
- APT1LG1
- CASP8
- CD95L
- DR4
- DR5
- FADD
- FAS
- FAS1
- FASL
- FASLG
- KILLER
- MCH5
- MORT1
- RIP
- RIP1
- RIPK1
- TNFRSF10A
- TNFRSF10B
- TNFRSF6
- TNFSF10
- TNFSF6
- TRADD
- TRAF2
- TRAIL
- TRAILR1
- TRAILR2
- TRAP3
- TRICK2
- ZTNFR9
|
Homo sapiens (human)
|
|
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
|
|
|
- ADRM1
- BTRC
- BTRCP
- C7orf76
- CUL1
- DSS1
- EMC19
- FBW1A
- FBXW1A
- GP110
- GSK3B
- HC2
- HC3
- HC8
- HC9
- HSPC
- KIAA0107
- LMPX
- LMPY
- MB1
- MIP224
- MOV34L
- MSS1
- NFE2L2
- NRF2
- NU
- OCP2
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RBX1
- RNF75
- ROC1
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SKP1
- SKP1A
- SUG1
- SUG2
- TBP1
- TBP7
- TCEB1L
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- X
- Y
- Z
|
Homo sapiens (human)
|
|
Synthesis of Hepoxilins (HX) and Trioxilins (TrX)
|
|
|
|
Homo sapiens (human)
|
|
The canonical retinoid cycle in rods (twilight vision)
|
|
|
- ABCA4
- ABCR
- ARSDR1
- CRALBP
- CRBP1
- CYP4V2
- DHRS9
- E17KSR
- EDH17B1
- EDH17B2
- EDHB17
- HSD17B1
- HSD17B6
- HSD17B9
- LRAT
- MYO7A
- OPN2
- PALB
- PRRDH
- PSDR1
- RBP1
- RBP3
- RBP4
- RDH1
- RDH10
- RDH11
- RDH12
- RDH15
- RDH16
- RDH5
- RDH8
- RDHS
- RHO
- RLBP1
- RODH
- RODH4
- RPE65
- SDR16C4
- SDR28C1
- SDR28C2
- SDR7C1
- SDR7C2
- SDR9C4
- SDR9C5
- SDR9C6
- SDR9C7
- SDR9C8
- SDRO
- STRA6
- TTR
- USH1B
|
Homo sapiens (human)
|
|
Defective ABCG5 causes sitosterolemia
|
|
|
|
Homo sapiens (human)
|
|
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
|
|
|
- AKR1C1
- AKR1C2
- AKR1C3
- AKR1C4
- AKR1D1
- BAR
- BHLHE74
- BHLHE75
- CHDR
- CYP12
- CYP27
- CYP27A1
- CYP7
- CYP7A1
- CYP7B1
- CYP8B1
- DDH
- DDH1
- DDH2
- FXR
- HRR1
- HSD17B5
- HSD3B7
- KIAA0119
- NCOA1
- NCOA2
- NR1H4
- NR2B1
- PGFS
- RIP14
- RXRA
- SRC1
- SRC2
- SRD5B1
- TIF2
|
Homo sapiens (human)
|
|
Autodegradation of the E3 ubiquitin ligase COP1
|
|
|
- ADRM1
- ATM
- C7orf76
- COP1
- DSS1
- GP110
- HC2
- HC3
- HC8
- HC9
- HSPC
- KIAA0107
- LMPX
- LMPY
- MB1
- MIP224
- MOV34L
- MSS1
- NU
- P53
- PFAAP4
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RFWD2
- RNF200
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SUG1
- SUG2
- TBP1
- TBP7
- TP53
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- X
- Y
- Z
|
Homo sapiens (human)
|
|
CASP8 activity is inhibited
|
|
|
- APO2
- APO2L
- APT1
- APT1LG1
- CASP8
- CD95L
- DR4
- DR5
- FADD
- FAS
- FAS1
- FASL
- FASLG
- KILLER
- MCH5
- MORT1
- RIP
- RIP1
- RIPK1
- TNFRSF10A
- TNFRSF10B
- TNFRSF6
- TNFSF10
- TNFSF6
- TRADD
- TRAF2
- TRAIL
- TRAILR1
- TRAILR2
- TRAP3
- TRICK2
- ZTNFR9
|
Homo sapiens (human)
|
|
Nef mediated downregulation of MHC class I complex cell surface expression
|
|
|
- ADTB1
- ADTG
- AP19
- AP1B1
- AP1G1
- AP1M1
- AP1M2
- AP1S1
- AP1S2
- AP1S3
- B2M
- BAM22
- CLAPB2
- CLAPG1
- CLAPS1
- CLTNM
- HLA-A
- HLAA
- KIAA1175
- PACS1
- nef
|
Homo sapiens (human)
|
|
G2/M DNA damage checkpoint
|
|
|
- ABRA1
- ABRAXAS1
- AGS1
- ATM
- ATR
- ATRIP
- BABAM1
- BABAM2
- BACH1
- BARD1
- BLM
- BLU
- BRCA1
- BRCC3
- BRCC36
- BRCC45
- BRE
- BRIP1
- C12orf32
- C16orf75
- C19orf62
- C6.1A
- C9orf76
- CCDC98
- CDS1
- CHEK1
- CHEK2
- CHK1
- CHK2
- CTIP
- CXorf53
- DNA2
- DNA2L
- EXO1
- EXOI
- FAM175A
- FANCJ
- FRP1
- H2AFX
- H2AX
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-4
- H3FT
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HERC2
- HEX1
- HIRIP1
- HIRIP2
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2BE
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST3H3
- HIST4H4
- HNGS1
- HTATIP
- HUS1
- KAT5
- KIAA0083
- KIAA0170
- KIAA0259
- KIAA0646
- KIAA1090
- MDC1
- MERIT40
- MMS2
- MMSET
- MRE11
- MRE11A
- NBA1
- NBN
- NBS
- NBS1
- NFBD1
- NSD2
- P53
- P95
- PIAS4
- PIASG
- R24L
- RAD1
- RAD17
- RAD50
- RAD53
- RAD9A
- RAD9B
- RAP80
- RBBP8
- REC1
- RECQ2
- RECQ3
- RECQL2
- RECQL3
- REPA1
- REPA2
- REPA3
- RFC2
- RFC3
- RFC4
- RFC5
- RHINO
- RHNO1
- RMI1
- RMI2
- RNF168
- RNF53
- RNF8
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- RXRIP110
- TIP60
- TOP3
- TOP3A
- TOPBP1
- TP53
- TP53BP1
- TRX5
- TSH2B
- UBE2N
- UBE2V2
- UEV2
- UIMC1
- WHSC1
- WRN
|
Homo sapiens (human)
|
|
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
|
|
|
- ADHFE1
- C14orf160
- D2HGD
- D2HGDH
- L2HGDH
|
Homo sapiens (human)
|
|
Glycosphingolipid transport
|
|
|
- ARF1
- BTS
- CLN3
- CPTP
- ESYT1
- ESYT2
- ESYT3
- FAM62A
- FAM62B
- FAM62C
- FAPP2
- GLTP
- GLTPD1
- KIAA0747
- KIAA1228
- MBC2
- PLEKHA8
|
Homo sapiens (human)
|
|
Signaling by EGFR
|
|
|
- AAMP
- ADAM10
- ADAM12
- ADAM17
- AREG
- AREGB
- BTC
- C20orf129
- C6orf143
- CSVP
- DTR
- DTS
- EGF
- EGFR
- EPGN
- ERBB
- ERBB1
- EREG
- FAM83A
- FAM83B
- FAM83D
- HBEGF
- HEGFL
- HER1
- KUZ
- LIG1
- LRIG1
- MADM
- MLTN
- SDGF
- TACE
- TGFA
- TSGP
|
Homo sapiens (human)
|
|
NADPH regeneration
|
|
|
|
Homo sapiens (human)
|
|
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome
|
|
|
|
Homo sapiens (human)
|
|
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
|
|
|
- ADRM1
- AIK
- AIK2
- AIM1
- AIRK1
- AIRK2
- ANAPC1
- ANAPC10
- ANAPC11
- ANAPC12
- ANAPC15
- ANAPC16
- ANAPC2
- ANAPC3
- ANAPC4
- ANAPC5
- ANAPC6
- ANAPC7
- ANAPC8
- APC10
- APC2
- APC4
- APC5
- APC7
- ARK1
- ARK2
- AURA
- AURKA
- AURKB
- AYK1
- BTAK
- C10orf104
- C11orf51
- C7orf76
- C9orf17
- CDC16
- CDC20
- CDC23
- CDC26
- CDC27
- CDH1
- CENP-27
- D0S1430E
- D17S978E
- DSS1
- E2EPF
- EAP1
- FBXL1
- FYR
- FZR
- FZR1
- GP110
- HC2
- HC3
- HC8
- HC9
- HSPC
- IAK1
- KIAA0107
- KIAA1242
- KIAA1406
- LMPX
- LMPY
- MB1
- MIP224
- MOV34L
- MSS1
- NU
- PFAAP4
- PLK
- PLK1
- POH1
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- PTTG
- PTTG1
- RB1
- RPS27A
- SEM1
- SFT
- SHFDG1
- SHFM1
- SKP2
- STK1
- STK12
- STK15
- STK5
- STK6
- SUG1
- SUG2
- TBP1
- TBP7
- TRAP2
- TSG24
- TUTR1
- UBA52
- UBA80
- UBB
- UBC
- UBC5A
- UBCEP1
- UBCEP2
- UBCH10
- UBCH5
- UBCH5A
- UBCH6
- UBE2C
- UBE2D1
- UBE2E1
- UBE2S
- X
- Y
- Z
|
Homo sapiens (human)
|
|
RPIA deficiency: failed conversion of R5P to RU5P
|
|
|
|
Homo sapiens (human)
|
|
Calnexin/calreticulin cycle
|
|
|
- CALR
- CANX
- CRTC
- ERP57
- ERP60
- G19P1
- G2AN
- GANAB
- GRP58
- KIAA0088
- PDIA3
- PRKCSH
|
Homo sapiens (human)
|
|
GABA synthesis, release, reuptake and degradation
|
|
|
- CLN4
- CPLX1
- DNAJC5
- GAD
- GAD1
- GAD2
- GAD65
- GAD67
- HSC70
- HSP73
- HSPA10
- HSPA8
- KIAA0340
- RAB3A
- RAB3IP2
- RIM1
- RIMS1
- SLC32A1
- SNAP
- SNAP25
- STX1
- STX1A
- SVP65
- SYB2
- SYT
- SYT1
- VAMP2
- VGAT
- VIAAT
|
Homo sapiens (human)
|
|
MECP2 regulates transcription factors
|
|
|
- A2BP
- A2BP1
- FOX1
- HRNBP1
- MEF2C
- NR1C3
- PPARG
- RBFOX1
|
Homo sapiens (human)
|
|
PTK6 Activates STAT3
|
|
|
- APRF
- BKS
- BRK
- CIS3
- PTK6
- SOCS3
- SSI3
- STAP2
- STAT3
|
Homo sapiens (human)
|
|
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
|
|
|
- CD14
- ESOP1
- IRAK2
- KIAA0733
- LY96
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- MD2
- PRVTIRB
- RNF85
- RPS27A
- TAB1
- TAB2
- TAB3
- TAK1
- TICAM1
- TICAM2
- TIRAP3
- TIRP
- TLR4
- TRAF6
- TRAM
- TRIF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
Homo sapiens (human)
|
|
Mitochondrial translation elongation
|
|
|
- AIP
- AKIP
- AURKAIP1
- BMRP
- BRIP1
- C10orf34
- C11orf4
- C15orf4
- C20orf193
- C21orf101
- C21orf92
- C2orf1
- C3orf5
- C6orf14
- CHCHD1
- DAP3
- DS1
- EFG
- EFG1
- ERAL1
- GADD45GIP1
- GFM
- GFM1
- HERA
- ICT1
- IMOGN38
- KGD4
- KIAA0104
- KIAA0264
- L23MRP
- LIECG2
- LIP2
- MAAT1
- MRL3
- MRP63
- MRP64
- MRPL1
- MRPL10
- MRPL11
- MRPL12
- MRPL13
- MRPL14
- MRPL15
- MRPL16
- MRPL17
- MRPL18
- MRPL19
- MRPL2
- MRPL20
- MRPL21
- MRPL22
- MRPL23
- MRPL24
- MRPL25
- MRPL27
- MRPL28
- MRPL3
- MRPL30
- MRPL31
- MRPL32
- MRPL33
- MRPL34
- MRPL35
- MRPL36
- MRPL37
- MRPL38
- MRPL39
- MRPL4
- MRPL40
- MRPL41
- MRPL42
- MRPL43
- MRPL44
- MRPL45
- MRPL46
- MRPL47
- MRPL48
- MRPL49
- MRPL5
- MRPL50
- MRPL51
- MRPL52
- MRPL53
- MRPL54
- MRPL55
- MRPL57
- MRPL58
- MRPL59
- MRPL7
- MRPL8
- MRPL9
- MRPS10
- MRPS11
- MRPS12
- MRPS14
- MRPS15
- MRPS16
- MRPS17
- MRPS18A
- MRPS18B
- MRPS18C
- MRPS2
- MRPS21
- MRPS22
- MRPS23
- MRPS24
- MRPS25
- MRPS26
- MRPS27
- MRPS28
- MRPS29
- MRPS30
- MRPS31
- MRPS32
- MRPS33
- MRPS34
- MRPS35
- MRPS36
- MRPS37
- MRPS38
- MRPS39
- MRPS5
- MRPS6
- MRPS7
- MRPS9
- NCM1
- NLVCF
- NOF1
- OXA1L
- PDCD9
- PLINP1
- PRG6
- PTCD3
- RPL23L
- RPML12
- RPML2
- RPML25
- RPML27
- RPML28
- RPML3
- RPML31
- RPML32
- RPML5
- RPML8
- RPMS11
- RPMS12
- RPMS13
- RPMS15
- RPMS16
- RPMS17
- RPMS21
- RPMS22
- RPMS25
- RPMS6
- RPMS9
- RPSM12
- TSFM
- TUFM
- URIM
|
Homo sapiens (human)
|
|
Signaling by ALK fusions and activated point mutants
|
|
|
- ALK
- ALO17
- APRF
- ASH
- ATIC
- BCL11A
- BCL2L3
- BIRC6
- C17orf27
- C2orf2
- C2orf44
- CAP20
- CARS
- CARS1
- CDKN1
- CDKN1A
- CIP1
- CLH17
- CLTC
- CLTCL2
- CTIP1
- DCTN1
- EEF1G
- EF1G
- EIF2AK3
- EMAPL4
- EML4
- EVI9
- FBX20
- FBXO20
- FN
- FN1
- FRS2
- FRS3
- GCC2
- GRB1
- GRB2
- HIP1
- IL10
- IL22
- ILTIF
- IRS1
- JNK1
- JNK2
- JUN
- KIAA0034
- KIAA0336
- KIAA0858
- KIAA0905
- KIAA1230
- KIAA1289
- KIAA1398
- KIAA1554
- KIAA1618
- KIAA1809
- KIF5B
- KLC
- KLC1
- KNS
- KNS1
- KNS2
- LMO7
- MAPK8
- MAPK9
- MCL1
- MDA6
- MDM2
- MSN
- MYH9
- MYSTR
- NPM
- NPM1
- NUP358
- ORCA
- OSIL
- P53
- PEK
- PERK
- PIC1
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PKR1
- PLC1
- PLCG1
- PP2CB
- PPFIBP1
- PPM1B
- PRKAR1
- PRKAR1A
- PRKM8
- PRKM9
- PURH
- RANBP2
- RANBP2L4
- RNF213
- RPS27A
- RRBP1
- SAPK1
- SAPK1A
- SAPK1C
- SDI1
- SEC31A
- SEC31L1
- SQSTM1
- STAT1
- STAT3
- STRN
- TFG
- TP53
- TPM3
- TPM4
- TPR
- TSE1
- TYK2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- VCL
- WAF1
- WDCP
- ZCYTO18
- ZNF856
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Homo sapiens (human)
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Defective ABCA3 causes SMDP3
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Homo sapiens (human)
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