GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1751 - 1775** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
STAT5 Activation	Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 2 Receptor-type tyrosine-protein kinase FLT3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein phosphatase non-receptor type 11	P36888 P42229 P49771 P51692 Q06124 Q9UQC2	CD135 FLK2 FLT3 FLT3LG GAB2 KIAA0571 PTP2C PTPN11 SHPTP2 STAT5 STAT5A STAT5B STK1	Homo sapiens (human)
Defective DPM2 causes CDG-1u	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein FLICE inhibitory protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 2 Toll-like receptor 4 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein Viral CASP8 and FADD-like apoptosis regulator	O00206 O00220 O14763 P08571 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628 Q76RF1 Q86XR7 Q8IUC6 Q98325 Q9Y6Y9	APO2 APO2L APT1 APT1LG1 CASP8 CD14 CD95L DR4 DR5 ESOP1 FADD FAS FAS1 FASL FASLG KILLER LY96 MC159L MCH5 MD2 MORT1 ORF71 PRVTIRB RIP RIP1 RIPK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAM TRAP3 TRICK2 TRIF ZTNFR9	Homo sapiens (human)
tRNA processing in the nucleus	ATP-dependent RNA helicase DDX1 Aladin Ashwin CCA tRNA nucleotidyltransferase 1, mitochondrial Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 4 Cleavage stimulation factor subunit 2 E3 SUMO-protein ligase RanBP2 Exportin-T GTP-binding nuclear protein Ran Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Polyribonucleotide 5'-hydroxyl-kinase Clp1 Protein FAM98B Protein SEC13 homolog Protein archease RNA transcription, translation and transport factor protein RNA-splicing ligase RtcB homolog Ribonuclease P protein subunit p14 Ribonuclease P protein subunit p20 Ribonuclease P protein subunit p21 Ribonuclease P protein subunit p25 Ribonuclease P protein subunit p29 Ribonuclease P protein subunit p30 Ribonuclease P protein subunit p38 Ribonuclease P protein subunit p40 Ribonuclease P/MRP protein subunit POP5 Ribonucleases P/MRP protein subunit POP1 Zinc phosphodiesterase ELAC protein 2 mRNA export factor RAE1 tRNA-splicing endonuclease subunit Sen15 tRNA-splicing endonuclease subunit Sen2 tRNA-splicing endonuclease subunit Sen34 tRNA-splicing endonuclease subunit Sen54	A8CG34 O15504 O43592 O75694 O75817 O75818 O95059 O95639 O95707 P12270 P33240 P35658 P37198 P49790 P49792 P55735 P57740 P62826 P78345 P78346 P78406 Q10570 Q12769 Q52LJ0 Q5SRE5 Q7Z3B4 Q7Z6J9 Q8IWT0 Q8N1F7 Q8NCE0 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q8WW01 Q92499 Q92621 Q92989 Q969H6 Q96HA1 Q96Q11 Q99567 Q99575 Q9BQ52 Q9BSV6 Q9BTX1 Q9BUL9 Q9BVC5 Q9BW27 Q9H633 Q9NRG9 Q9UKX7 Q9Y224 Q9Y3I0	AAAS ADRACALA ARA24 ARCH C14orf166 C1orf19 C22orf28 C2orf49 C6orf135 C7orf14 CAIN CAN CAT60 CG1 CLP1 CPSF1 CPSF160 CPSF30 CPSF4 CSTF2 D3S1231E DDX1 ELAC2 FAM98B HEAB HPC2 KIAA0023 KIAA0061 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 LENG5 MP44 MRNP41 NAR NDC1 NEB1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C POP1 POP4 POP5 POP7 RAE1 RAN RANBP2 RNASEP1 RNASEP2 RPP14 RPP20 RPP21 RPP25 RPP29 RPP30 RPP38 RPP40 RTCB RTRAF SEC13 SEC13A SEC13L1 SEC13R SEN15 SEN2 SEN34 SEN54 TMEM48 TPR TRNT1 TSEN15 TSEN2 TSEN34 TSEN54 XPOT ZBTB8OS	Homo sapiens (human)
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Sharpin Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 1 TNF receptor-associated factor 2 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD	O14920 O15111 O43318 O75604 P01375 P19438 P21580 P63244 P98170 Q12933 Q13077 Q13107 Q13489 Q13490 Q13546 Q15628 Q15750 Q5VV17 Q6GQQ9 Q8N5C8 Q96CV9 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9NYJ8 Q9UK80 Q9UM82 Q9Y6K9	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CHUK CYLD CYLD1 DUBA7 EBI6 FIP2 FIP3 GLC1E GNB2L1 HIP7 HYPL IAP3 IKBKB IKBKG IKKA IKKB KIAA0733 KIAA0757 KIAA0849 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MIHB MIHC NEMO NRP OPTN OTDC1 OTUD1 OTUD7B OTUD7C PD1 RACK1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 SHARPIN SIPL1 SPATA2 TAB1 TAB2 TAB3 TAK1 TCF16 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF1 TRAF2 TRAP3 UBCE7IP3 UBP41 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA	Homo sapiens (human)
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin-3 Drebrin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoproteins C1/C2 Hsp90 co-chaperone Cdc37 PH-interacting protein RNA-binding motif protein, X chromosome RNA-binding protein Musashi homolog 2 Rho-related BTB domain-containing protein 2 Serine/arginine repetitive matrix protein 1 Serine/threonine-protein kinase 38 Spliceosome RNA helicase DDX39B T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Tropomodulin-3 Twinfilin-1 Unconventional myosin-VI	O43396 P07900 P07910 P08238 P12814 P38159 P40227 P62995 P63261 P78371 Q12792 Q13618 Q13838 Q15208 Q16543 Q16643 Q8IYB3 Q8WWQ0 Q96DH6 Q99832 Q9BYZ6 Q9NYL9 Q9UM54	99D8.1 ACTG ACTG1 ACTN1 BAT1 CCT2 CCT6 CCT6A CCT7 CCTB CCTH CCTZ CDC37 CDC37A CUL3 D0S117E DBC2 DBN1 DCAF14 DDX39B HNRNPC HNRPC HNRPG HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0389 KIAA0617 KIAA0717 MSI2 MYO6 NDR1 NIP7-1 PHIP PTK9 RBMX RBMXP1 RHOBTB2 SFRS10 SRM160 SRRM1 STK38 TMOD3 TRA2B TRP32 TWF1 TXL TXNL TXNL1 UAP56 WDR11	Homo sapiens (human)
DAG and IP3 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Protein kinase C delta type Protein kinase C epsilon type S-adenosylhomocysteine hydrolase-like protein 1	O43865 P19174 Q02156 Q05655 Q14571 Q14573 Q14643	AHCYL1 DCAL INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 PKCD PKCE PLC1 PLCG1 PRKCD PRKCE XPVKONA	Homo sapiens (human)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Free fatty acid receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15	O14842 O95837 P29992 P30679 P50148 Q00722 Q01970 Q9NQ66	FFAR1 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ GPR40 KIAA0581 PLCB1 PLCB2 PLCB3	Homo sapiens (human)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	3 beta-hydroxysteroid dehydrogenase type 7 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Acyl-coenzyme A thioesterase 8 Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1 member C2 Aldo-keto reductase family 1 member C3 Aldo-keto reductase family 1 member C4 Aldo-keto reductase family 1 member D1 Alpha-methylacyl-CoA racemase Bile acid receptor Bile acid-CoA Bile salt export pump Cytochrome P450 7A1 Cytochrome P450 7B1 Long-chain fatty acid transport protein 2 Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal multifunctional enzyme type 2 Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial	O14734 O14975 O75881 O95342 P17516 P19793 P22680 P42330 P51659 P51857 P52895 Q02318 Q04828 Q14032 Q15596 Q15788 Q96RI1 Q99424 Q9H2F3 Q9UHK6 Q9UNU6 Q9Y2P5	ABCB11 ACOT8 ACOX2 ACSB ACSVL1 ACSVL6 ACTEIII AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 AMACR BAAT BAR BHLHE74 BHLHE75 BSEP CHDR CYP12 CYP27 CYP27A1 CYP7 CYP7A1 CYP7B1 CYP8B1 DDH DDH1 DDH2 EDH17B4 FACVL1 FACVL3 FATP2 FATP5 FXR HRR1 HSD17B4 HSD17B5 HSD3B7 KIAA0119 NCOA1 NCOA2 NR1H4 NR2B1 PGFS PTE1 RIP14 RXRA SDR8C1 SLC27A2 SLC27A5 SRC1 SRC2 SRD5B1 TIF2 VLACS	Homo sapiens (human)
Mitochondrial Fatty Acid Beta-Oxidation	3-ketoacyl-CoA thiolase, mitochondrial Acetyl-coenzyme A thioesterase Acyl carrier protein, mitochondrial Acyl-CoA dehydrogenase family member 10 Acyl-CoA dehydrogenase family member 11 Acyl-CoA-binding domain-containing protein 6 Acyl-CoA-binding domain-containing protein 7 Acyl-CoA-binding protein Acyl-coenzyme A thioesterase 11 Acyl-coenzyme A thioesterase 13 Acyl-coenzyme A thioesterase 1 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 9, mitochondrial Acyl-coenzyme A thioesterase THEM4 Acyl-coenzyme A thioesterase THEM5 Cytosolic acyl coenzyme A thioester hydrolase Malonyl-CoA-acyl carrier protein transacylase, mitochondrial Medium-chain acyl-CoA ligase ACSF2, mitochondrial Phosphatidylcholine transfer protein Putative cytosolic acyl coenzyme A thioester hydrolase-like	O00154 O14561 P07108 P42765 P49753 Q5T1C6 Q6JQN1 Q6ZUV0 Q709F0 Q86TX2 Q8IVS2 Q8N1Q8 Q8N6N7 Q8WXI4 Q8WYK0 Q96CM8 Q9BR61 Q9NPJ3 Q9UKL6 Q9Y305	ACAA2 ACAD10 ACAD11 ACBD6 ACBD7 ACOT1 ACOT11 ACOT12 ACOT13 ACOT15 ACOT2 ACOT7 ACOT7L ACOT9 ACSF2 BACH BACHL BFIT CACH CACH1 CTE1 CTMP DBI KIAA0707 MCAT MT NDUFAB1 PCTP PTE2 PTE2A STARD15 STARD2 THEA THEM2 THEM4 THEM5	Homo sapiens (human)
Uptake and function of diphtheria toxin	CD9 antigen Diphtheria toxin Elongation factor 2 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Proheparin-binding EGF-like growth factor Thioredoxin reductase 1, cytoplasmic	P00588 P07900 P08238 P13639 P21926 Q16881 Q99075	CD9 DTR DTS EEF2 EF2 GRIM12 HBEGF HEGFL HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KDRF MIC3 TSPAN29 TXNRD1	Homo sapiens (human)
Trafficking of AMPA receptors	A-kinase anchor protein 5 Band 4.1-like protein 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Disks large homolog 1 Disks large homolog 4 E3 ubiquitin-protein ligase Mdm2 Glutamate receptor 1 Glutamate receptor 3 Glutamate receptor 4 Unconventional myosin-VI Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-3 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-8 subunit	O60359 P24588 P42261 P42263 P48058 P78352 Q00987 Q12959 Q13554 Q13555 Q13557 Q8WXS5 Q9H4G0 Q9UBN1 Q9UM54 Q9UQM7 Q9Y698	AKAP5 AKAP79 CACNG2 CACNG3 CACNG4 CACNG6 CACNG8 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG DLG1 DLG4 EPB41L1 GLUA1 GLUH1 GLUR1 GLUR3 GLUR4 GLURC GRIA1 GRIA3 GRIA4 GluA3 GluA4 KIAA0338 KIAA0389 KIAA0968 MDM2 MYO6 PSD95	Homo sapiens (human)
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15455 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q8IUC6 Q92844 Q96CV9 Q9UHD2	CAP-1 CRAF1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TLR3 TRAF2 TRAF3 TRAFAMN TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Defective translocation of RB1 mutants to the nucleus	Retinoblastoma-associated protein	P06400	RB1	Homo sapiens (human)
PI3K events in ERBB4 signaling	Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor	O14511 O14944 P27986 P35070 P42336 P56975 Q02297 Q8WWG1 Q99075	BTC DTR DTS EREG GGF GRB1 HBEGF HEGFL HGL HRGA NDF NRG1 NRG2 NRG3 NRG4 NTAK PIK3CA PIK3R1 SMDF	Homo sapiens (human)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
Synthesis of PIPs at the Golgi membrane	1-phosphatidylinositol 3-phosphate 5-kinase ADP-ribosylation factor 1 ADP-ribosylation factor 3 Inositol polyphosphate 5-phosphatase OCRL Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase alpha Phosphatidylinositol 4-kinase beta Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol polyphosphate 5-phosphatase type IV Phosphatidylinositol-3-phosphatase SAC1 Phosphoinositide 3-kinase regulatory subunit 4 Polyphosphoinositide phosphatase Protein VAC14 homolog Putative tyrosine-protein phosphatase TPTE	O00443 O75747 P42356 P56180 P61204 P84077 Q01968 Q08AM6 Q6XPS3 Q8NEB9 Q8TCG2 Q92562 Q99570 Q9BTU6 Q9NRR6 Q9NTJ5 Q9UBF8 Q9Y2I7	ARF1 ARF3 FIG4 INPP5E KIAA0274 KIAA0851 KIAA0981 OCRL OCRL1 PI4K2A PI4K2B PI4KA PI4KB PIK3C2A PIK3C2G PIK3C3 PIK3R4 PIK4 PIK4CA PIK4CB PIKFYVE PIP5K3 SAC1 SAC3 SACM1L TAX1BP2 TPIP TPTE TPTE2 TRX VAC14 VPS15 VPS34	Homo sapiens (human)
Membrane binding and targetting of GAG proteins	Gag polyprotein Glycylpeptide N-tetradecanoyltransferase 2 Multivesicular body subunit 12A Multivesicular body subunit 12B Polyubiquitin-B Polyubiquitin-C Tumor susceptibility gene 101 protein Ubiquitin-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein sorting-associated protein 37A Vacuolar protein sorting-associated protein 37B Vacuolar protein sorting-associated protein 37C Vacuolar protein sorting-associated protein 37D	A5D8V6 O60551 P04591 P0CG47 P0CG48 P62979 P62987 Q86XT2 Q8NEZ2 Q96EY5 Q99816 Q9H7P6 Q9H9H4 Q9NZ09 Q9UK41	C9orf28 CFBP FAM125A FAM125B HCRP1 MVB12A MVB12B NMT2 PML39 RPS27A TSG101 UBA52 UBA80 UBAP1 UBB UBC UBCEP1 UBCEP2 VPS28 VPS37A VPS37B VPS37C VPS37D WBSCR24 gag	Homo sapiens (human)
Defective SLC7A7 causes lysinuric protein intolerance (LPI)	Amino acid transporter heavy chain SLC3A2 Y+L amino acid transporter 1	P08195 Q9UM01	MDU1 SLC3A2 SLC7A7	Homo sapiens (human)
PERK regulates gene expression	Cyclic AMP-dependent transcription factor ATF-4 Endoplasmic reticulum chaperone BiP Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 2-alpha kinase 3	P05198 P11021 P18848 P20042 P41091 Q9NZJ5	ATF4 CREB2 EIF2A EIF2AK3 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 GRP78 HSPA5 PEK PERK TXREB	Homo sapiens (human)
Defective CD320 causes MMATC	CD320 antigen Transcobalamin-2	P20062 Q9NPF0	8D6A CD320 TC2 TCN2	Homo sapiens (human)
Retrograde neurotrophin signalling	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Beta-nerve growth factor Clathrin heavy chain 1 Clathrin light chain A Dynamin-1 Dynamin-2 Dynamin-3 Dynein axonemal light chain 4 Endophilin-A1 High affinity nerve growth factor receptor	O94973 O95782 O96015 P01138 P04629 P09496 P50570 P53680 P63010 Q00610 Q05193 Q96CW1 Q99962 Q9UQ16	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 CNSA2 DNAL4 DNM DNM1 DNM2 DNM3 DYN2 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0820 KIAA0899 MTC NGF NGFB NTRK1 SH3D2A SH3GL2 TRK TRKA	Homo sapiens (human)
Defective SLC6A19 causes Hartnup disorder (HND)	Sodium-dependent neutral amino acid transporter B(0)AT1	Q695T7	B0AT1 SLC6A19	Homo sapiens (human)
TNFR1-induced proapoptotic signaling	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase-8 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Inhibitor of nuclear factor kappa-B kinase subunit epsilon OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Serine/threonine-protein kinase TBK1 Sharpin Spermatogenesis-associated protein 2 TNF receptor-associated factor 2 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Uncharacterized protein UL36	O75604 P01375 P16767 P19438 P21580 P98170 Q12933 Q13107 Q13158 Q13489 Q13490 Q13546 Q14164 Q14790 Q15628 Q5VV17 Q6GQQ9 Q96AX9 Q96CV9 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9UHD2 Q9UK80 Q9UM82	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CASP8 CYLD CYLD1 DUBA7 FADD FIP2 GLC1E HIP7 HYPL IAP3 IKBKE IKKE IKKI KIAA0151 KIAA0757 KIAA0849 MCH5 MIB2 MIHB MIHC MORT1 NAK NRP OPTN OTDC1 OTUD1 OTUD7B OTUD7C PD1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 SHARPIN SIPL1 SKD SPATA2 TBK1 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF2 TRAP3 UBCE7IP3 UBP41 UL36 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA ZZANK1	Homo sapiens (human)
Regulation of localization of FOXO transcription factors	14-3-3 protein beta/alpha 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	A8MYZ6 O43524 P27348 P31749 P31751 P31946 P31947 P61981 P63104 P98177 Q12778 Q9Y243	AFX AFX1 AKT1 AKT2 AKT3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 HME1 MLLT7 PKB PKBG RAC SFN YWHAB YWHAG YWHAQ YWHAZ	Homo sapiens (human)

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