GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1801 - 1825** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Nuclear events mediated by NFE2L2	5'-AMP-activated protein kinase catalytic subunit alpha-2 CREB-binding protein Histone acetyltransferase p300 Kelch-like ECH-associated protein 1 Nuclear factor erythroid 2-related factor 2 Sequestosome-1 Transcription factor MafG Transcription factor MafK Tumor suppressor ARF	O15525 O60675 P54646 Q09472 Q13501 Q14145 Q16236 Q8N726 Q92793	AMPK AMPK2 CBP CDKN2 CDKN2A CREBBP EP300 INRF2 KEAP1 KIAA0132 KLHL19 MAFG MAFK MLM NFE2L2 NRF2 ORCA OSIL P300 PRKAA2 SQSTM1	Homo sapiens (human)
IRF3-mediated induction of type I IFN	DNA-dependent protein kinase catalytic subunit Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase DTX4 Gamma-interferon-inducible protein 16 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 NLR family CARD domain-containing protein 3 Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Three-prime repair exonuclease 1 X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	P12956 P13010 P49959 P78527 Q14653 Q16666 Q7RTR2 Q86WV6 Q96MN2 Q9NSU2 Q9UHD2 Q9UJV9 Q9Y2E6	ABS DDX41 DTX4 ERIS G22P1 G22P2 HNGS1 HYRC HYRC1 IFI16 IFNGIP1 IRF3 KIAA0937 MITA MRE11 MRE11A NAK NALP4 NLRC3 NLRP4 NOD3 PAN2 PRKDC PYPAF4 RNF155 RNH2 STING STING1 TBK1 TMEM173 TREX1 XRCC5 XRCC6	Homo sapiens (human)
Fanconi Anemia Pathway	5' exonuclease Apollo ATR-interacting protein Centromere protein S Centromere protein X Crossover junction endonuclease EME1 Crossover junction endonuclease MUS81 DNA cross-link repair 1A protein DNA excision repair protein ERCC-1 DNA polymerase nu DNA repair endonuclease XPF E3 ubiquitin-protein ligase FANCL Fanconi anemia core complex-associated protein 100 Fanconi anemia core complex-associated protein 20 Fanconi anemia core complex-associated protein 24 Fanconi anemia group A protein Fanconi anemia group B protein Fanconi anemia group C protein Fanconi anemia group D2 protein Fanconi anemia group E protein Fanconi anemia group F protein Fanconi anemia group G protein Fanconi anemia group I protein Fanconi anemia group M protein Fanconi-associated nuclease 1 Polyubiquitin-B Polyubiquitin-C Probable crossover junction endonuclease EME2 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine/threonine-protein kinase ATR Structure-specific endonuclease subunit SLX1 Structure-specific endonuclease subunit SLX4 Ubiquitin carboxyl-terminal hydrolase 1 Ubiquitin-conjugating enzyme E2 T Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 48	A4GXA9 A8MT69 O15287 O15360 O94782 P07992 P0CG47 P0CG48 P15927 P27694 P35244 P62979 P62987 Q00597 Q0VG06 Q13535 Q6NZ36 Q6PJP8 Q7Z5Q5 Q8IY92 Q8IYD8 Q8N2Z9 Q8NB91 Q8TAF3 Q8WXE1 Q92889 Q96AY2 Q96NY9 Q9BQ83 Q9BTP7 Q9BXW9 Q9H816 Q9HB96 Q9NPD8 Q9NPI8 Q9NVI1 Q9NW38 Q9Y2M0	AGS1 APITD1 ATR ATRIP BTBD12 C17orf70 C19orf40 C1orf86 CENPS CENPX DCLRE1A DCLRE1B EME1 EME2 ERCC1 ERCC11 ERCC4 FAA FAAP10 FAAP100 FAAP16 FAAP20 FAAP24 FAC FACA FACC FACD FACE FAN1 FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCH FANCI FANCL FANCM FRP1 GIYD1 GIYD2 KIAA0086 KIAA1018 KIAA1449 KIAA1596 KIAA1784 KIAA1794 KIAA1987 MHF1 MHF2 MMS4 MTMR15 MUS81 PHF9 POLN REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SLX1 SLX1A SLX1B SLX4 SNM1 SNM1A SNM1B STRA13 UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2T USP1 WDR48 XPF XRCC9	Homo sapiens (human)
Signaling by ERBB2	Epidermal growth factor receptor Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor tyrosine-protein kinase erbB-2 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Yes	O14511 O14944 P00533 P01133 P04626 P06241 P07900 P07947 P12931 P35070 P56975 Q02297 Q16543 Q8WWG1 Q96RT1 Q99075	BTC CDC37 CDC37A DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG FYN GGF HBEGF HEGFL HER1 HER2 HGL HRGA HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NDF NEU NGL NRG1 NRG2 NRG3 NRG4 NTAK SMDF SRC SRC1 YES YES1	Homo sapiens (human)
Attenuation phase	CREB-binding protein DnaJ homolog subfamily B member 1 Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor protein 1 Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Histone acetyltransferase p300 Peptidyl-prolyl cis-trans isomerase FKBP4 Prostaglandin E synthase 3	O75506 P07900 P08238 P0DMV8 P0DMV9 P11142 P25685 P34931 P54652 Q00613 Q02790 Q09472 Q15185 Q92793	CBP CREBBP DNAJ1 DNAJB1 EP300 FKBP4 FKBP52 HDJ1 HSBP1 HSC70 HSF1 HSF1BP HSP72 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB HSPF1 HSTF1 HSX70 P23 P300 PTGES3 TEBP	Homo sapiens (human)
E3 ubiquitin ligases ubiquitinate target proteins	B-cell lymphoma/leukemia 10 DNA-dependent protein kinase catalytic subunit Derlin-1 E3 ubiquitin-protein ligase BRE1A E3 ubiquitin-protein ligase BRE1B E3 ubiquitin-protein ligase RAD18 E3 ubiquitin-protein ligase RNF144A E3 ubiquitin-protein ligase RNF152 E3 ubiquitin-protein ligase RNF181 E3 ubiquitin-protein ligase SHPRH E3 ubiquitin-protein ligase TM129 HLA class I histocompatibility antigen, A alpha chain Helicase-like transcription factor Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O MHC Class I antigen (B60) (Fragment) Parafibromin Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisome assembly protein 12 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen RNA polymerase II-associated factor 1 homolog RNA polymerase-associated protein CTR9 homolog RNA polymerase-associated protein LEO1 RNA polymerase-associated protein RTF1 homolog Ras-related GTP-binding protein A Selenoprotein S Superkiller complex protein 8 Transitional endoplasmic reticulum ATPase Ubiquitin-conjugating enzyme E2 A Ubiquitin-conjugating enzyme E2 B Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 J2 Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Unique short US11 glycoprotein WW domain-containing adapter protein with coiled-coil	A0AVI4 O00623 O60683 O60814 O75150 O75381 O95999 P04439 P06899 P09727 P0CG47 P0CG48 P12004 P23527 P28328 P33778 P49459 P50876 P51668 P51965 P55072 P58876 P61077 P61088 P62807 P62837 P62979 P62987 P63146 P68036 P78527 Q14527 Q149N8 Q15819 Q5VTR2 Q6P1J9 Q6PD62 Q7L523 Q8N2K1 Q8N7H5 Q8N8N0 Q8WVC0 Q92541 Q92968 Q93079 Q96A08 Q99877 Q99879 Q99880 Q9BQE4 Q9BTA9 Q9BUN8 Q9GZS3 Q9MY60 Q9NS91 Q9P0P0	BCL10 BLU BRE1A BRE1B C1orf28 CDC73 CIPER CLAP CTR9 DER1 DERL1 H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFR H2BFT HEL-220 HEL-S-70 HIP116A HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HLA-A HLA-B HLAA HLTF HRPT2 HYRC HYRC1 KIAA0155 KIAA0161 KIAA0252 KIAA0661 KIAA1844 KIAA2023 LEO1 MMS2 NCUBE2 PAF1 PAF3 PCNA PD2 PEX10 PEX12 PEX13 PEX14 PEX2 PMP3 PMP35 PRKDC PUBC1 PXMP3 RAD18 RAD6A RAD6B RDL RNF144 RNF144A RNF152 RNF181 RNF20 RNF40 RNF69 RNF72 RNF73 RNF80 RPS27A RRAGA RTF1 SELENOS SELS SFT SH2BP1 SHPRH SKIC8 SMARCA3 SNF2L3 TMEM129 TSH2B UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCE7 UBCE7IP4 UBCEP1 UBCEP2 UBCH1 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBCH6 UBCH7 UBE2A UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2J2 UBE2L3 UBE2N UBE2V2 UEV2 US11 VCP VIMP WAC WDR61 ZBU1	Homo sapiens (human)
WNT mediated activation of DVL	Casein kinase I isoform epsilon Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3	O14640 O14641 O14986 P19784 P49674 P67870 P68400 Q92997	CK2A1 CK2A2 CK2N CSNK1E CSNK2A1 CSNK2A2 CSNK2B DVL1 DVL2 DVL3 G5A KIAA0208 PIP5K1B STM7	Homo sapiens (human)
Synthesis, secretion, and deacylation of Ghrelin	Acetylcholinesterase Cholinesterase Corticotropin-releasing factor receptor 2 Ghrelin O-acyltransferase Insulin-like growth factor I Insulin Krueppel-like factor 4 Leptin Neuroendocrine convertase 1 Platelet-activating factor acetylhydrolase Pro-glucagon Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Somatotropin Urocortin	O43474 P01241 P01275 P01308 P05019 P06276 P22303 P29120 P41159 P55089 P61009 P67812 Q13093 Q13324 Q15005 Q96T53 Q9BY50 Q9Y6A9	ACHE BCHE CHE1 CRF2R CRH2R CRHR2 EZF GCG GH1 GKLF GOAT IBP1 IGF1 INS KIAA0102 KLF4 LEP MBOAT4 NEC1 OACT4 OB OBS PAFAH PCSK1 PLA2G7 SEC11A SEC11C SEC11L1 SEC11L3 SPC12 SPC18 SPC21 SPC22 SPC25 SPCS1 SPCS2 SPCS3 SPCS4A SPCS4C UCN	Homo sapiens (human)	G58161NS
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	ADP-ribosylation factor 1 AH receptor-interacting protein Annexin A2 BolA-like protein 2 Calponin-2 Carbonic anhydrase 1 Cell division control protein 42 homolog Cofilin-1 F-actin-capping protein subunit alpha-1 Glutathione S-transferase A2 Glutathione S-transferase omega-1 Heterogeneous nuclear ribonucleoprotein D-like Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoproteins A2/B1 Interferon gamma Interleukin-10 Lamin-B1 Large ribosomal subunit protein uL10 Macrophage migration inhibitory factor Moesin Peptidyl-prolyl cis-trans isomerase A Phosphatidylinositol transfer protein alpha isoform Plasminogen activator inhibitor 2 Plastin-2 Programmed cell death protein 4 Proteasome activator complex subunit 2 Ras-related protein Ral-A Ras-related protein Rap-1b S-methyl-5'-thioadenosine phosphorylase Serine/threonine-protein kinase PAK 2 Signal transducer and activator of transcription 4 Stress-70 protein, mitochondrial Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial T-complex protein 1 subunit alpha Transaldolase U2 small nuclear ribonucleoprotein A'	O00170 O14979 P00441 P00915 P01579 P04179 P05120 P05388 P07355 P09210 P09661 P11233 P13796 P14174 P17987 P20700 P22301 P22626 P23528 P26038 P37837 P38646 P52597 P52907 P60953 P61224 P62937 P78417 P84077 Q00169 Q13126 Q13177 Q14765 Q53EL6 Q99439 Q9H3K6 Q9UL46	AIP ANX2 ANX2L4 ANXA2 ARF1 BOLA2 BOLA2A BOLA2B CA1 CAL1H CAPZA1 CCT1 CCTA CDC42 CFL CFL1 CNN2 CYPA GLIF GRP75 GST2 GSTA2 GSTO1 GSTTLP28 H731 HNRNPA2B1 HNRNPDL HNRNPF HNRPA2B1 HNRPDL HNRPF HSPA9 HSPA9B IFNG IL10 JKTBP LCP1 LMN2 LMNB LMNB1 LPC2D MIF MMIF MSAP MSN MTAP PAI2 PAK2 PDCD4 PITPN PITPNA PLANH2 PLS2 PPIA PSME2 RAL RALA RAP1B RPLP0 SERPINB2 SNRPA1 SOD1 SOD2 STAT4 TAL TALDO TALDO1 TALDOR TCP1 XAP2 mt-HSP70	Homo sapiens (human)
Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN)	Ammonium transporter Rh type A	Q02094	RH50 RHAG	Homo sapiens (human)
Axonal growth inhibition (RHOA activation)	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 Myelin-associated glycoprotein Oligodendrocyte-myelin glycoprotein Proto-oncogene DBL Reticulon-4 Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P08138 P10911 P20916 P23515 P52565 P61586 Q96FE5 Q9NQC3	ARH12 ARHA ARHGDIA DBL GDIA1 GMA KIAA0886 LERN1 LINGO1 LRRN6A MAG MCF2 NGFR NOGO OMG OMGP RHO12 RHOA RTN4 TNFRSF16	Homo sapiens (human)
Synthesis of PE	Choline kinase alpha Choline/ethanolamine kinase Choline/ethanolaminephosphotransferase 1 Ethanolamine kinase 1 Ethanolamine kinase 2 Ethanolamine-phosphate cytidylyltransferase Ethanolamine-phosphate phospho-lyase Ethanolaminephosphotransferase 1 Phosphatidate phosphatase LPIN1 Phosphatidate phosphatase LPIN2 Phosphatidate phosphatase LPIN3 Phosphatidylserine decarboxylase proenzyme, mitochondrial Phosphoethanolamine/phosphocholine phosphatase	P35790 Q14693 Q8TBG4 Q8TCT1 Q92539 Q99447 Q9BQK8 Q9C0D9 Q9HBU6 Q9NVF9 Q9UG56 Q9Y259 Q9Y6K0	AGXT2L1 CEPT1 CHETK CHK CHKA CHKB CHKL CKI EKI1 EKI2 EPT1 ETNK1 ETNK2 ETNPPL KIAA0188 KIAA0249 KIAA1724 LIPN3L LPIN1 LPIN2 LPIN3 PCYT2 PHOSPHO1 PISD SELENOI SELI	Homo sapiens (human)
Cysteine formation from homocysteine	Cystathionine beta-synthase Cystathionine gamma-lyase	P32929 P35520	CBS CTH	Homo sapiens (human)
NGF-stimulated transcription	Achaete-scute homolog 1 Activity-regulated cytoskeleton-associated protein Chromodomain-helicase-DNA-binding protein 4 Cyclic AMP-dependent transcription factor ATF-1 Cyclic AMP-dependent transcription factor ATF-2 Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 activator 2 Cyclin-dependent kinase 5 DNA-binding protein inhibitor ID-1 DNA-binding protein inhibitor ID-2 DNA-binding protein inhibitor ID-3 DNA-binding protein inhibitor ID-4 Dynamin-2 E3 SUMO-protein ligase EGR2 ETS domain-containing protein Elk-1 Early growth response protein 1 Early growth response protein 3 Early growth response protein 4 Endophilin-A3 Fos-related antigen 1 GTP-binding protein RAD Histone acetyltransferase p300 Myocyte-specific enhancer factor 2D NGFI-A-binding protein 1 NGFI-A-binding protein 2 Neurosecretory protein VGF Protein FosB Protein c-Fos Protein lyl-1 RE1-silencing transcription factor Serine/threonine-protein kinase Sgk1 Serum response factor Tissue factor Transcription factor 12 Transcription factor JunB Transcription factor JunD Tribbles homolog 1 Tryptophan 5-hydroxylase 1	O00141 O15240 P01100 P11161 P11831 P12980 P13726 P15336 P15407 P17275 P17535 P17752 P18146 P18846 P19419 P41134 P47928 P50553 P50570 P53539 P55042 Q00535 Q02363 Q02535 Q05215 Q06889 Q09472 Q13127 Q13319 Q13506 Q14814 Q14839 Q15078 Q15742 Q7LC44 Q96RU8 Q99081 Q99963	1R21 ARC ASCL1 ASH1 ATF1 ATF2 BHLHA18 BHLHA46 BHLHB20 BHLHB24 BHLHB25 BHLHB26 BHLHB27 C8FW CDK5 CDK5R CDK5R1 CDK5R2 CDKN5 CHD4 CNSA3 CREB2 CREBP1 DNM2 DYN2 EGR1 EGR2 EGR3 EGR4 ELK1 EP300 F3 FOS FOSB FOSL1 FRA1 G0S3 G0S7 GIG2 HASH1 HEB HEIR1 HTF4 ID ID1 ID2 ID3 ID4 JUNB JUND KIAA0278 KROX20 KROX24 LYL1 MADER MEF2D NAB1 NAB2 NCK5A NCK5AI NRSF P300 PILOT PSSALRE RAD REST RRAD SGK SGK1 SH3D2C SH3GL3 SRF TCF12 TPH TPH1 TPRH TRB1 TRIB1 TRPH VGF XBR ZNF225	Homo sapiens (human)
Toll Like Receptor 10 (TLR10) Cascade	Toll-like receptor 10	Q9BXR5	TLR10	Homo sapiens (human)
Switching of origins to a post-replicative state	DNA replication factor Cdt1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Geminin	O75496 P25205 P33991 P33992 P33993 P49736 Q14566 Q9H211	BM28 CCNL1 CDC21 CDC46 CDC47 CDCL1 CDT1 GMNN KIAA0030 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7	Homo sapiens (human)
Anchoring of the basal body to the plasma membrane	14-3-3 protein epsilon 14-3-3 protein gamma A-kinase anchor protein 9 Alpha-centractin B9 domain-containing protein 1 B9 domain-containing protein 2 C2 domain-containing protein 3 CDK5 regulatory subunit-associated protein 2 CLIP-associating protein 1 Casein kinase I isoform delta Casein kinase I isoform epsilon Centrin-2 Centriolar coiled-coil protein of 110 kDa Centriole and centriolar satellite protein OFD1 Centriolin Centromere protein J Centrosomal protein 43 Centrosomal protein of 131 kDa Centrosomal protein of 135 kDa Centrosomal protein of 152 kDa Centrosomal protein of 162 kDa Centrosomal protein of 164 kDa Centrosomal protein of 192 kDa Centrosomal protein of 290 kDa Centrosomal protein of 41 kDa Centrosomal protein of 57 kDa Centrosomal protein of 63 kDa Centrosomal protein of 70 kDa Centrosomal protein of 72 kDa Centrosomal protein of 76 kDa Centrosomal protein of 78 kDa Centrosomal protein of 83 kDa Centrosomal protein of 89 kDa Centrosomal protein of 97 kDa Centrosome-associated protein ALMS1 Centrosome-associated protein CEP250 Coiled-coil and C2 domain-containing protein 2A Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoskeleton-associated protein 5 Dynactin subunit 2 Dynactin subunit 3 Dynein light chain 1, cytoplasmic Fas-binding factor 1 HAUS augmin-like complex subunit 1 HAUS augmin-like complex subunit 2 HAUS augmin-like complex subunit 3 HAUS augmin-like complex subunit 4 HAUS augmin-like complex subunit 5 HAUS augmin-like complex subunit 6 HAUS augmin-like complex subunit 7 HAUS augmin-like complex subunit 8 Heat shock protein HSP 90-alpha IQ calmodulin-binding motif-containing protein 1 Jouberin Kinesin-like protein KIF24 MAP/microtubule affinity-regulating kinase 4 Meckelin Microtubule nucleation factor SSNA1 Microtubule-associated protein RP/EB family member 1 Nephrocystin-1 Nephrocystin-4 Ninein-like protein Nuclear distribution protein nudE homolog 1 Outer dense fiber protein 2 Pericentrin Pericentriolar material 1 protein Platelet-activating factor acetylhydrolase IB subunit beta Protein NEDD1 Protein SFI1 homolog Protein fantom Rab-3A-interacting protein Ras-related protein Rab-11A Ras-related protein Rab-8A Septin-2 Serine/threonine-protein kinase Nek2 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serologically defined colon cancer antigen 8 Sodium channel and clathrin linker 1 Tau-tubulin kinase 2 Tectonic-1 Tectonic-2 Tectonic-3 Tectonic-like complex member MKS1 Transmembrane protein 216 Tubulin alpha-1A chain Tubulin alpha-4A chain Tubulin beta chain Tubulin beta-4A chain Tubulin beta-4B chain Tubulin gamma-1 chain cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type II-beta regulatory subunit	A8K8P3 O00444 O15078 O15259 O43303 O43805 O75161 O75665 O75935 O94927 O94986 O95613 O95684 P04350 P06493 P07437 P07900 P17612 P23258 P30153 P31323 P41208 P43034 P48730 P49674 P51955 P53350 P61006 P61163 P61981 P62258 P62491 P63167 P68366 P68371 Q13409 Q13561 Q14008 Q14204 Q15019 Q15051 Q15154 Q15691 Q2MV58 Q4AC94 Q5BJF6 Q5HYA8 Q5JTW2 Q5T7B8 Q5TB80 Q66GS9 Q68CZ1 Q68CZ6 Q6IQ55 Q6NUS6 Q71U36 Q7Z460 Q7Z4H7 Q7Z7A1 Q86SQ7 Q86XR8 Q8IW35 Q8N157 Q8NHQ1 Q8NHV4 Q8TAP6 Q8TCU4 Q8TEP8 Q8TES7 Q96CS2 Q96GX1 Q96L34 Q96MT8 Q96NL6 Q96QF0 Q96SN8 Q96ST8 Q99871 Q99996 Q9BPU9 Q9BT25 Q9BV73 Q9BYV8 Q9H6D7 Q9HC77 Q9NVX0 Q9NXB0 Q9NXR1 Q9P0N5 Q9P209 Q9P2K1 Q9UPM9 Q9UPN4 Q9UPV0 Q9Y2I6 Q9Y592	ACTR1A AHI1 AKAP350 AKAP450 AKAP9 ALB ALMS1 AZI1 B9D1 B9D2 BBS14 BITE C10orf61 C12orf38 C14orf94 C15orf25 C18orf9 C2CD3 C4orf15 C6orf84 C9orf48 C9orf81 CALT CC2D2A CCCAP CCDC123 CCDC41 CCDC5 CCP110 CDC2 CDC28A CDK1 CDK5RAP2 CDKN1 CEN2 CENPJ CEP1 CEP110 CEP131 CEP135 CEP152 CEP162 CEP164 CEP192 CEP2 CEP215 CEP250 CEP27 CEP290 CEP4 CEP41 CEP43 CEP57 CEP63 CEP70 CEP72 CEP76 CEP78 CEP83 CEP89 CEP97 CETN2 CKAP5 CLASP1 CNAP1 CNTRL CP110 CPAP CSNK1D CSNK1E CTRN1 CXorf5 DCTN2 DCTN22 DCTN3 DCTN50 DGT6 DHC1 DIFF6 DLC1 DNCH1 DNCI2 DNCIC2 DNCL DNCL1 DNCLC1 DNECL DYHC DYNC1H1 DYNC1I2 DYNLL1 FAM29A FBF1 FGFR1OP FOP FTM HAUS1 HAUS2 HAUS3 HAUS4 HAUS5 HAUS6 HAUS7 HAUS8 HCKID HDLC1 HEIC HICE1 HSP90A HSP90AA1 HSPC1 HSPCA IQCB1 KIAA0036 KIAA0092 KIAA0097 KIAA0158 KIAA0325 KIAA0328 KIAA0373 KIAA0402 KIAA0419 KIAA0542 KIAA0622 KIAA0635 KIAA0673 KIAA0803 KIAA0841 KIAA0847 KIAA0912 KIAA0980 KIAA1005 KIAA1009 KIAA1052 KIAA1118 KIAA1345 KIAA1519 KIAA1569 KIAA1574 KIAA1633 KIAA1860 KIAA1863 KIF24 LAP LIP1 LIS1 LRRIQ2 MAPRE1 MARK4 MARKL1 MAST1 MDCR MDS MEL MKS1 MKS3 MKSR1 MKSR2 NA14 NDE1 NEDD1 NEDD5 NEK2 NEK2A NINL NLK1 NLP NPH1 NPHP1 NPHP10 NPHP15 NPHP4 NPHP5 NPHP6 NPHP8 NUDE ODF2 OFD1 P34CDC2 PAFAH1B1 PAFAHA PCM1 PCNT PCNT2 PKACA PLK PLK1 PLK4 PPP2R1A PRKACA PRKAR2B QN1 RAB11 RAB11A RAB3IP RAB8 RAB8A RABIN8 RPGRIP1L SAK SAP1 SCLT1 SDCCAG8 SEPT2 SEPTIN2 SFI1 SSNA1 STK18 TCTN1 TCTN2 TCTN3 TECT1 TECT2 TECT3 TMEM216 TMEM67 TSGA14 TSP57 TTBK2 TUBA1 TUBA1A TUBA3 TUBA4A TUBB TUBB2C TUBB4 TUBB4A TUBB4B TUBB5 TUBG TUBG1 UCHL5IP UIP1 YWHAE YWHAG	Homo sapiens (human)
Uncoating of the HIV Virion	Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Nef Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04601 P04618 P05919 P62937 P69723 P69726	CYPA PPIA gag gag-pol nef rev vif vpr vpu	Homo sapiens (human)
ER Quality Control Compartment (ERQC)	Derlin-2 E3 ubiquitin-protein ligase AMFR E3 ubiquitin-protein ligase MARCHF6 E3 ubiquitin-protein ligase RNF103 E3 ubiquitin-protein ligase RNF139 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 E3 ubiquitin-protein ligase TRIM13 E3 ubiquitin-protein ligase synoviolin ER degradation-enhancing alpha-mannosidase-like protein 1 ER degradation-enhancing alpha-mannosidase-like protein 2 ER degradation-enhancing alpha-mannosidase-like protein 3 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Polyubiquitin-B Polyubiquitin-C Protein OS-9 Protein sel-1 homolog 1 UDP-glucose UDP-glucose Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00237 O60337 O60858 P0CG47 P0CG48 P62979 P62987 Q13438 Q86TM6 Q8WU17 Q92611 Q96GF1 Q99942 Q9BV94 Q9BZQ6 Q9GZP9 Q9NYU1 Q9NYU2 Q9UBV2 Q9UKM7 Q9UKV5	AMFR C1orf22 C20orf31 C20orf49 DER2 DERL2 EDEM EDEM1 EDEM2 EDEM3 FLANA G16 GT HRD1 KIAA0212 KIAA0597 KIAA1810 LEU5 MAN1B1 MARCH6 MARCHF6 NG2 OS9 RFP2 RMA1 RNF103 RNF139 RNF176 RNF185 RNF45 RNF5 RNF77 RPS27A SEL1L SYVN1 TEB4 TRC8 TRIM13 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UGCGL1 UGCGL2 UGGT UGGT1 UGGT2 UGT1 UGT2 UGTR ZFP103	Homo sapiens (human)	G70323CJ G93575MM
HDL remodeling	ATP-binding cassette sub-family G member 1 Albumin Apolipoprotein A-I Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Cholesteryl ester transfer protein Endothelial lipase Phosphatidylcholine-sterol acyltransferase	P02647 P02649 P02655 P02656 P02768 P04180 P11597 P45844 Q9Y5X9	ABC8 ABCG1 ALB APC2 APOA1 APOC2 APOC3 APOE CETP LCAT LIPG WHT1	Homo sapiens (human)
MyD88 cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Flagellin Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 1 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 10 Toll-like receptor 5	O43187 O60602 P04949 P51617 Q13233 Q99836 Q9BQ95 Q9BXR5 Q9NWZ3 Q9Y4K3	ECSIT IRAK IRAK1 IRAK2 IRAK4 MAP3K1 MAPKKK1 MEKK MEKK1 MYD88 RNF85 TIL3 TLR10 TLR5 TRAF6 flaF fliC hag	Homo sapiens (human)
Sphingolipid de novo biosynthesis	3-ketodihydrosphingosine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Casein kinase I isoform gamma-2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 type B Fatty acid 2-hydroxylase Multidrug resistance-associated protein 1 ORM1-like protein 1 ORM1-like protein 2 ORM1-like protein 3 Oxysterol-binding protein 1 Phosphatidylcholine Phosphatidylcholine Protein phosphatase 1L Serine palmitoyltransferase 1 Serine palmitoyltransferase 2 Serine palmitoyltransferase 3 Serine palmitoyltransferase small subunit A Serine palmitoyltransferase small subunit B Serine/threonine-protein kinase D1 Serine/threonine-protein kinase D2 Serine/threonine-protein kinase D3 Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 Sphingomyelin synthase-related protein 1 Sphingosine kinase 1 Sphingosine kinase 2 Sphingosine-1-phosphate transporter MFSD2B Sphingosine-1-phosphate transporter SPNS2 Vesicle-associated membrane protein-associated protein A Vesicle-associated membrane protein-associated protein B/C	A6NFX1 O15121 O15269 O15270 O43169 O94806 O95292 P22059 P27544 P33527 P78368 Q06136 Q15139 Q53FV1 Q5SGD2 Q6QHC5 Q6ZMG9 Q7L5A8 Q86VZ5 Q8IU89 Q8IVW8 Q8N138 Q8N5B7 Q8NFR3 Q8NHU3 Q969W0 Q96G23 Q96LT4 Q9BZL6 Q9HA82 Q9NRA0 Q9NUV7 Q9NYA1 Q9P0L0 Q9P0S3 Q9UNQ0	ABCC1 ABCG2 ABCP ADMP BCRP BCRP1 C14orf147 C14orf66 C20orf38 C3orf57 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CK1G2 CSNK1G2 CYB5B CYB5M DEGS1 DEGS2 DES1 EPK2 FA2H FAAH FAXDC1 FVT1 KDSR KIAA0526 LAG1 LASS1 LASS2 LASS3 LASS4 LASS5 LASS6 LCB1 LCB2 MFSD2B MLD MOB MRP MRP1 MXR OMB5 ORMDL1 ORMDL2 ORMDL3 OSBP OSBP1 PKD PKD1 PKD2 PP2CE PPM1L PRKCM PRKCN PRKD1 PRKD2 PRKD3 SAMD8 SDR35C1 SGMS1 SGMS2 SK1 SK2 SMS1 SMS2 SPHK SPHK1 SPHK2 SPK SPNS2 SPTLC1 SPTLC2 SPTLC2L SPTLC3 SPTSSA SPTSSB SSSPTA SSSPTB TMEM23 TMSG1 UOG1 VAP33 VAPA VAPB	Homo sapiens (human)
Gain-of-function MRAS complexes activate RAF signaling	14-3-3 protein beta/alpha Leucine-rich repeat protein SHOC-2 RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	O14807 P04049 P10398 P15056 P31946 P36873 P62140 Q9UQ13	ARAF ARAF1 BRAF BRAF1 KIAA0862 MRAS PKS PKS2 PPP1CB PPP1CC RAF RAF1 RAFB1 RRAS3 SHOC2 YWHAB	Homo sapiens (human)
Toxicity of botulinum toxin type C (botC)	Botulinum neurotoxin type C Synaptosomal-associated protein 25 Syntaxin-1A Syntaxin-1B	P18640 P60880 P61266 Q16623	SNAP SNAP25 STX1 STX1A STX1B STX1B1 STX1B2	Homo sapiens (human)
APC truncation mutants have impaired AXIN binding	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX	Homo sapiens (human)

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