GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **2074** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
2-LTR circle formation	Barrier-to-autointegration factor DNA ligase 4 DNA repair protein XRCC4 Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Protein Rev Protein Vpr Protein Vpu Virion infectivity factor X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	O75475 O75531 P04585 P04591 P04618 P05919 P12956 P13010 P17096 P49917 P69723 P69726 Q13426	BAF BANF1 BCRG1 DFS70 G22P1 G22P2 HMGA1 HMGIY LEDGF LIG4 PSIP1 PSIP2 XRCC4 XRCC5 XRCC6 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
3-Methylcrotonyl-CoA carboxylase deficiency	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	Q96RQ3 Q9HCC0	MCCA MCCB MCCC1 MCCC2	Homo sapiens (human)
A tetrasaccharide linker sequence is required for GAG synthesis	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Beta-1,3-galactosyltransferase 6 Beta-1,4-galactosyltransferase 7 Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Neurocan core protein Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Versican core protein Xylosyltransferase 1 Xylosyltransferase 2	O00468 O14594 O75056 O75487 O94766 O95196 P07585 P13611 P18827 P21810 P31431 P34741 P35052 P51654 P78333 P98160 Q6UVK1 Q86Y38 Q8N158 Q96GW7 Q96L58 Q9H1B5 Q9NPZ5 Q9P2W7 Q9UBV7 Q9Y625	AGRIN AGRN B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 BCAN BEHAB BGN CALEB CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN GLCATP GLCATS GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HSPG1 HSPG2 KIAA0468 KIAA1963 MCSP NCAN NEUR NGC OCI5 SDC SDC1 SDC2 SDC3 SDC4 SLRR1A SLRR1B VCAN XGALT1 XT1 XT2 XYLT1 XYLT2	Homo sapiens (human)
ABC transporters in lipid homeostasis	ATP-binding cassette sub-family A member 10 ATP-binding cassette sub-family A member 2 ATP-binding cassette sub-family A member 6 ATP-binding cassette sub-family A member 9 ATP-binding cassette sub-family D member 1 ATP-binding cassette sub-family D member 2 ATP-binding cassette sub-family D member 3 ATP-binding cassette sub-family G member 1 ATP-binding cassette sub-family G member 4 ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8 Apolipoprotein A-I Cholesterol transporter ABCA5 Glucosylceramide transporter ABCA12 Peroxisomal biogenesis factor 19 Peroxisomal biogenesis factor 3 Phospholipid-transporting ATPase ABCA3 Phospholipid-transporting ATPase ABCA7	P02647 P28288 P33897 P40855 P45844 P56589 Q86UK0 Q8IUA7 Q8IZY2 Q8N139 Q8WWZ4 Q8WWZ7 Q99758 Q9BZC7 Q9H172 Q9H221 Q9H222 Q9UBJ2	ABC12 ABC2 ABC3 ABC8 ABCA10 ABCA12 ABCA2 ABCA3 ABCA5 ABCA6 ABCA7 ABCA9 ABCD1 ABCD2 ABCD3 ABCG1 ABCG4 ABCG5 ABCG8 ALD ALD1 ALDL1 ALDR ALDRP APOA1 HK33 KIAA1062 KIAA1888 PEX19 PEX3 PMP70 PXF PXMP1 WHITE2 WHT1	Homo sapiens (human)
ABC-family proteins mediated transport	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type oligopeptide transporter ABCB9 ABC-type organic anion transporter ABCA8 ATP-binding cassette sub-family B member 5 ATP-binding cassette sub-family C member 10 ATP-binding cassette sub-family C member 11 ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 ATP-binding cassette sub-family C member 6 ATP-binding cassette sub-family C member 9 ATP-binding cassette sub-family F member 1 ATP-dependent translocase ABCB1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin-2 Derlin-3 E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin 1 Erlin-1 Erlin-2 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Multidrug resistance-associated protein 1 Phosphatidylcholine translocator ABCB4 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein OS-9 Protein sel-1 homolog 1 Retinal-specific phospholipid-transporting ATPase ABCA4 Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O15438 O15439 O15440 O43242 O60706 O75477 O94905 O94911 O95255 P05198 P08183 P0CG47 P0CG48 P13569 P17980 P20042 P20618 P21439 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P33527 P35998 P41091 P43686 P48556 P49720 P49721 P51665 P55072 P60896 P60900 P62191 P62195 P62333 P62979 P62987 P78363 Q13200 Q13438 Q14654 Q15008 Q16186 Q2M3G0 Q5T3U5 Q8NE71 Q92887 Q96DZ1 Q96GF1 Q96J66 Q96Q80 Q99436 Q99460 Q99942 Q9BUN8 Q9GZP9 Q9NP78 Q9UBV2 Q9UNM6	ABC50 ABCA4 ABCA8 ABCB1 ABCB4 ABCB5 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC4 ABCC5 ABCC6 ABCC7 ABCC9 ABCF1 ABCR ADRM1 ARA C10orf69 C22orf14 C2orf30 C7orf76 C8orf2 CFTR CMOAT CMOAT1 CMOAT2 CMRP DER1 DER2 DER3 DERL1 DERL2 DERL3 DSS1 EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 FLANA G16 GP110 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HSPC KCNJ11 KE04 KEO4 KIAA0107 KIAA0822 KIAA1520 LLN2 LMPX LMPY MB1 MDR1 MDR3 MIP224 MLP2 MOATB MOV34L MRP MRP1 MRP2 MRP3 MRP4 MRP5 MRP6 MRP7 MRP8 MSS1 NG2 NU OS9 PFAAP4 PGY1 PGY3 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RMA1 RNF185 RNF5 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SIMRP7 SPFH1 SPFH2 SUG1 SUG2 SUR2 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Z	Homo sapiens (human)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Histo-blood group ABO system transferase	P16442 P19526 Q10981	ABO FUT1 FUT2 H HSC SEC2	Homo sapiens (human)
ADORA2B mediated anti-inflammatory cytokines production	Adenosine receptor A2b Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Interleukin-6 cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A8MTJ3 O14610 O14775 O43306 O60262 O60266 O60503 O95622 P04899 P05231 P08754 P10644 P13861 P16520 P17612 P19086 P22612 P22694 P29275 P31321 P31323 P40145 P50150 P50151 P51817 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADORA2B GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP IFNB2 IL6 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PKX1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX TSE1	Homo sapiens (human)
ADP signalling through P2Y purinoceptor 1	Cytosolic phospholipase A2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Mitogen-activated protein kinase 14 P2Y purinoceptor 1	O14610 O14775 O60262 O95837 P16520 P29992 P30679 P47712 P47900 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q16539 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	CPLA2 CSBP CSBP1 CSBP2 CSPB1 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 MAPK14 MXI2 P2RY1 PLA2G4 PLA2G4A SAPK2A	Homo sapiens (human)
ADP signalling through P2Y purinoceptor 12	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 P2Y purinoceptor 12	A8MTJ3 O14610 O14775 O60262 P04899 P08754 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63096 P63211 P63215 P63218 Q9H244 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	GNAI1 GNAI2 GNAI2B GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 HORK3 P2RY12	Homo sapiens (human)
AKT phosphorylates targets in the cytosol	Bcl2-associated agonist of cell death Caspase-9 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase makorin-1 Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Inhibitor of nuclear factor kappa-B kinase subunit alpha Proline-rich AKT1 substrate 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tuberin	O15111 P31749 P31751 P38936 P46527 P49815 P49840 P49841 P55211 Q00987 Q92934 Q96B36 Q9UHC7 Q9Y243	AKT1 AKT1S1 AKT2 AKT3 BAD BBC6 BCL2L8 CAP20 CASP9 CDKN1 CDKN1A CDKN1B CHUK CIP1 GSK3A GSK3B IKKA KIP1 MCH6 MDA6 MDM2 MKRN1 PIC1 PKB PKBG PRAS40 RAC RNF61 SDI1 TCF16 TSC2 TSC4 WAF1 p27	Homo sapiens (human)
AKT phosphorylates targets in the nucleus	Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Nuclear receptor subfamily 4immunitygroup A member 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ribosomal protein S6 kinase beta-2	A8MYZ6 O43524 P22736 P31749 P31751 P98177 Q12778 Q9UBS0 Q9Y243	AFX AFX1 AKT1 AKT2 AKT3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 GFRP1 HMR MLLT7 NAK1 NR4A1 PKB PKBG RAC RPS6KB2 STK14B	Homo sapiens (human)
AKT-mediated inactivation of FOXO1A	Forkhead box protein O1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	P31749 P31751 Q12778 Q9Y243	AKT1 AKT2 AKT3 FKHR FOXO1 FOXO1A PKB PKBG RAC	Homo sapiens (human)
ALK mutants bind TKIs	ALK tyrosine kinase receptor B-cell lymphoma/leukemia 11A Baculoviral IAP repeat-containing protein 6 Clathrin heavy chain 1 Echinoderm microtubule-associated protein-like 4 Eukaryotic translation initiation factor 2-alpha kinase 3 Fibronectin Huntingtin-interacting protein 1 Nucleophosmin Protein phosphatase 1B Striatin cAMP-dependent protein kinase type I-alpha regulatory subunit	O00291 O43815 O75688 P02751 P06748 P10644 Q00610 Q9H165 Q9HC35 Q9NR09 Q9NZJ5 Q9UM73	ALK BCL11A BIRC6 C2orf2 CLH17 CLTC CLTCL2 CTIP1 EIF2AK3 EMAPL4 EML4 EVI9 FN FN1 HIP1 KIAA0034 KIAA1289 KIAA1809 NPM NPM1 PEK PERK PKR1 PP2CB PPM1B PRKAR1 PRKAR1A STRN TSE1 ZNF856	Homo sapiens (human)
ALKBH2 mediated reversal of alkylation damage	DNA oxidative demethylase ALKBH2	Q6NS38	ABH2 ALKBH2	Homo sapiens (human)
ALKBH3 mediated reversal of alkylation damage	Activating signal cointegrator 1 complex subunit 1 Activating signal cointegrator 1 complex subunit 2 Activating signal cointegrator 1 complex subunit 3 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	Q8N3C0 Q8N9N2 Q96Q83 Q9H1I8	ABH3 ALKBH3 ASC1P100 ASCC1 ASCC2 ASCC3 DEPC1 HELIC1 RQT2 RQT3	Homo sapiens (human)
ALPK1 signaling pathway	Alpha-protein kinase 1 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 TRAF-interacting protein with FHA domain-containing protein A Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43318 P0CG47 P0CG48 P62979 P62987 Q15750 Q8N5C8 Q96CG3 Q96QP1 Q9NYJ8 Q9Y4K3	ALPK1 KIAA0733 KIAA1527 LAK MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 RNF85 RPS27A T2BP TAB1 TAB2 TAB3 TAK1 TIFA TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
AMPK inhibits chREBP transcriptional activation activity	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-2 Adiponectin receptor protein 1 Adiponectin receptor protein 2 Adiponectin Carbohydrate-responsive element-binding protein Serine/threonine-protein kinase STK11	O43741 P54646 Q15831 Q15848 Q86V24 Q96A54 Q9NP71 Q9UGJ0	ACDC ACRP30 ADIPOQ ADIPOR1 ADIPOR2 AMPK AMPK2 APM1 BHLHD14 GBP28 LKB1 MIO MLXIPL PAQR1 PAQR2 PJS PRKAA2 PRKAB2 PRKAG2 STK11 TESBP1A WBSCR14	Homo sapiens (human)
APAP ADME	ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 4 ATP-binding cassette sub-family C member 5 Aminoacylase-1 Arylamine N-acetyltransferase 1 Arylamine N-acetyltransferase 2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Glutathione S-transferase Mu 1 Glutathione S-transferase P Glutathione S-transferase theta-1 Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Multidrug resistance-associated protein 1 Putative glutathione hydrolase 3 proenzyme Sulfotransferase 1A1 Sulfotransferase 1A3 Sulfotransferase 1A4 Sulfotransferase 1C4 Sulfotransferase 1E1 Sulfotransferase 2A1 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A10 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A9 UDP-glucuronosyltransferase 2B15	A6NGU5 O15438 O15439 O15440 O60656 O75897 P05181 P09211 P09488 P0DMM9 P0DMN0 P11245 P18440 P19224 P19440 P22309 P30711 P33527 P36269 P49888 P50225 P54855 Q03154 Q06520 Q6P531 Q92887 Q96KP4 Q9HAW8 Q9UJ14 Q9UNQ0	AAC1 AAC2 ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABCP ACY1 BCRP BCRP1 CMOAT CMOAT1 CMOAT2 CMRP CN2 CNDP2 CPGL CYP2E CYP2E1 FAEES3 GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GNT1 GST1 GST3 GSTM1 GSTP1 GSTT1 HEL-S-13 HST MLP2 MOATB MRP MRP1 MRP2 MRP3 MRP4 MRP5 MXR NAT1 NAT2 PEPA STD STE STM STP STP1 SULT1A1 SULT1A3 SULT1A4 SULT1C2 SULT1C4 SULT1E1 SULT2A1 UGT1 UGT1A1 UGT1A10 UGT1A6 UGT1A9 UGT2B15 UGT2B8	Homo sapiens (human)
APC truncation mutants are not K63 polyubiquitinated	Adenomatous polyposis coli protein	P25054	APC DP2.5	Homo sapiens (human)
APC truncation mutants have impaired AXIN binding	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX	Homo sapiens (human)
APC-Cdc20 mediated degradation of Nek2A	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase Nek2 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 O43684 O60566 P0CG47 P0CG48 P30260 P51668 P51955 P51965 P60006 P62979 P62987 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L NEK2 NEK2A NLK1 RPS27A SFT SSK1 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
APC/C:Cdc20 mediated degradation of Cyclin B	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Polyubiquitin-B Polyubiquitin-C Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 P06493 P0CG47 P0CG48 P14635 P30260 P51668 P51965 P60006 P62979 P62987 Q12834 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CCNB CCNB1 CDC16 CDC2 CDC20 CDC23 CDC26 CDC27 CDC28A CDK1 CDKN1 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 P34CDC2 RPS27A SFT TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
APC/C:Cdc20 mediated degradation of Securin	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Securin Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O00762 O14818 O43242 O95997 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30260 P35998 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P60006 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q12834 Q13042 Q13200 Q15008 Q16186 Q16763 Q8NHZ8 Q96DE5 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13 Q9UNM6	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E DSS1 E2EPF EAP1 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 KIAA1406 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTTG PTTG1 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 TUTR1 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Z	Homo sapiens (human)
APC/C:Cdc20 mediated degradation of mitotic proteins	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 O43684 O60566 P30260 P51668 P51965 P60006 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L SFT SSK1 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Aurora kinase A Aurora kinase B Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Retinoblastoma-associated protein S-phase kinase-associated protein 2 Securin Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O00762 O14818 O14965 O43242 O95997 P06400 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30260 P35998 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P53350 P60006 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q12834 Q13042 Q13200 Q13309 Q15008 Q16186 Q16763 Q8NHZ8 Q96DE5 Q96GD4 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13 Q9UNM6	ADRM1 AIK AIK2 AIM1 AIRK1 AIRK2 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 ARK1 ARK2 AURA AURKA AURKB AYK1 BTAK C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF EAP1 FBXL1 FYR FZR FZR1 GP110 HC2 HC3 HC8 HC9 HSPC IAK1 KIAA0107 KIAA1242 KIAA1406 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 PLK PLK1 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTTG PTTG1 RB1 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP2 STK1 STK12 STK15 STK5 STK6 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 TUTR1 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Z	Homo sapiens (human)

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