GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1051 - 1075** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol
Repression of WNT target genes	C-terminal-binding protein 1 C-terminal-binding protein 2 Histone deacetylase 1 Lymphoid enhancer-binding factor 1 TLE family member 5 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7 Transducin-like enhancer protein 1 Transducin-like enhancer protein 2 Transducin-like enhancer protein 3 Transducin-like enhancer protein 4	P36402 P56545 Q04724 Q04725 Q04726 Q04727 Q08117 Q13363 Q13547 Q9HCS4 Q9NQB0 Q9UJU2	AES CTBP CTBP1 CTBP2 GRG GRG4 GRG5 HDAC1 KIAA1261 KIAA1547 LEF1 RPD3L1 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 TLE1 TLE2 TLE3 TLE4 TLE5
Classical antibody-mediated complement activation	C-reactive protein Complement C1q subcomponent subunit A Complement C1q subcomponent subunit B Complement C1q subcomponent subunit C Complement C1r subcomponent Complement C1s subcomponent IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 P00736 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P02741 P02745 P02746 P02747 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P09871 P0CF74 P0CG04 P0DOY2 P0DOY3 P23083 P80748 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0	C1QA C1QB C1QC C1QG C1R C1S CRP IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 PTX1 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6
Signaling by ROBO receptors	C-X-C chemokine receptor type 4 Ena/VASP-like protein Glypican-1 Leucine-rich repeat transmembrane protein FLRT3 Neuropilin-1 Profilin-1 Profilin-2 Protein enabled homolog Roundabout homolog 1 Roundabout homolog 2 Slit homolog 1 protein Slit homolog 2 protein Slit homolog 3 protein Stromal cell-derived factor 1 Vasodilator-stimulated phosphoprotein	O14786 O75093 O75094 O94813 P07737 P35052 P35080 P48061 P50552 P61073 Q8N8S7 Q9HCK4 Q9NZU0 Q9UI08 Q9Y6N7	CXCL12 CXCR4 DUTT1 ENAH EVL FLRT3 GPC1 KIAA0813 KIAA0814 KIAA1469 KIAA1568 MEGF4 MEGF5 MENA NRP NRP1 PFN1 PFN2 RNB6 ROBO1 ROBO2 SDF1 SDF1A SDF1B SLIL1 SLIL2 SLIL3 SLIT1 SLIT2 SLIT3 VASP VEGF165R
Formation of definitive endoderm	C-X-C chemokine receptor type 4 Cadherin-1 Catenin beta-1 Eomesodermin homolog Hepatocyte nuclear factor 3-beta Homeobox protein MIXL1 Homeobox protein goosecoid Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 T-box transcription factor T Transcription factor 7-like 2 Transcription factor GATA-4 Transcription factor GATA-6 Transcription factor SOX-17	O15178 O95936 P12830 P35222 P43694 P56915 P61073 P84022 Q13485 Q15796 Q92908 Q9H2W2 Q9H6I2 Q9NQB0 Q9Y261	CDH1 CDHE CTNNB CTNNB1 CXCR4 DPC4 EOMES FOXA2 GATA4 GATA6 GSC HNF3B MADH2 MADH3 MADH4 MADR2 MIXL MIXL1 SMAD2 SMAD3 SMAD4 SOX17 T TBR2 TBXT TCF3B TCF4 TCF7L2 UVO
NFE2L2 regulating inflammation associated genes	C-C motif chemokine 2 CREB-binding protein Histone acetyltransferase p300 Nuclear factor erythroid 2-related factor 2 Transcription factor MafK	O60675 P13500 Q09472 Q16236 Q92793	CBP CCL2 CREBBP EP300 MAFK MCP1 NFE2L2 NRF2 P300 SCYA2
Binding and entry of HIV virion	C-C chemokine receptor type 5 C-X-C chemokine receptor type 4 Envelope glycoprotein gp160 Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Nef Protein Rev Protein Vpr Protein Vpu T-cell surface glycoprotein CD4 Virion infectivity factor	P01730 P04578 P04585 P04591 P04601 P04618 P05919 P51681 P61073 P62937 P69723 P69726	CCR5 CD4 CMKBR5 CXCR4 CYPA PPIA env gag gag-pol nef rev vif vpr vpu
Interleukin-10 signaling	C-C chemokine receptor type 1 C-C chemokine receptor type 2 C-C chemokine receptor type 5 C-C motif chemokine 19 C-C motif chemokine 20 C-C motif chemokine 22 C-C motif chemokine 2 C-C motif chemokine 3-like 1 C-C motif chemokine 3 C-C motif chemokine 4 C-C motif chemokine 5 C-X-C motif chemokine 10 C-X-C motif chemokine 2 Granulocyte colony-stimulating factor Granulocyte-macrophage colony-stimulating factor Growth-regulated alpha protein Intercellular adhesion molecule 1 Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-10 receptor subunit alpha Interleukin-10 receptor subunit beta Interleukin-10 Interleukin-12 subunit alpha Interleukin-12 subunit beta Interleukin-18 Interleukin-6 Interleukin-8 Leukemia inhibitory factor Low affinity immunoglobulin epsilon Fc receptor Macrophage colony-stimulating factor 1 Metalloproteinase inhibitor 1 Non-receptor tyrosine-protein kinase TYK2 Platelet-activating factor receptor Prostaglandin G/H synthase 2 Signal transducer and activator of transcription 3 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor Tyrosine-protein kinase JAK1 fMet-Leu-Phe receptor	O00626 P01033 P01375 P01583 P01584 P02778 P04141 P05231 P05362 P06734 P09341 P09603 P09919 P10145 P10147 P13236 P13500 P13501 P14778 P15018 P16619 P18510 P19438 P19875 P20333 P21462 P22301 P23458 P25105 P27930 P29459 P29460 P29597 P32246 P33681 P35354 P40763 P41597 P42081 P51681 P78556 Q08334 Q13651 Q14116 Q99731	APRF C17orf33 CCL19 CCL2 CCL20 CCL22 CCL3 CCL3L1 CCL3L3 CCL4 CCL5 CCR1 CCR2 CCR5 CD23A CD28LG CD28LG1 CD28LG2 CD80 CD86 CLEC4J CLGI CMKBR1 CMKBR2 CMKBR5 CMKR1 COX2 CRFB4 CSF1 CSF2 CSF3 CXCL1 CXCL10 CXCL2 CXCL8 D17S136E D17S1718 D21S58 D21S66 ELC FCE2 FCER2 FPR1 G0S19-1 G0S19-2 GCSF GMCSF GRO GRO1 GRO2 GROA GROB HILDA ICAM1 IFNB2 IGEBF IGIF IL10 IL10R IL10RA IL10RB IL12A IL12B IL18 IL1A IL1B IL1F1 IL1F2 IL1F3 IL1F4 IL1R IL1R1 IL1R2 IL1RA IL1RB IL1RN IL1RT1 IL6 IL8 INP10 JAK1 JAK1A JAK1B LAB7 LAG1 LARC LIF MCP1 MDC MGSA MIP1A MIP1B MIP2A MIP3A MIP3B NKSF1 NKSF2 PAFR PTAFR PTGS2 SCYA19 SCYA2 SCYA20 SCYA22 SCYA3 SCYA3L1 SCYA4 SCYA5 SCYAR1 SCYB1 SCYB10 SCYB2 STAT3 TIMP TIMP1 TNF TNFA TNFAR TNFBR TNFR1 TNFR2 TNFRSF1A TNFRSF1B TNFSF2 TYK2
Butyrophilin (BTN) family interactions	Butyrophilin subfamily 1 member A1 Butyrophilin subfamily 2 member A1 Butyrophilin subfamily 2 member A2 Butyrophilin subfamily 3 member A1 Butyrophilin subfamily 3 member A2 Butyrophilin subfamily 3 member A3 Butyrophilin-like protein 2 Butyrophilin-like protein 8 Butyrophilin-like protein 9 CD209 antigen Periplakin Xanthine dehydrogenase/oxidase	O00478 O00481 O60437 P47989 P78410 Q13410 Q6UX41 Q6UXG8 Q7KYR7 Q8WVV5 Q9NNX6 Q9UIR0	BT2.1 BT2.2 BT3.2 BTF1 BTF2 BTF3 BTF4 BTF5 BTN BTN1A1 BTN2A1 BTN2A2 BTN3A1 BTN3A2 BTN3A3 BTNL2 BTNL8 BTNL9 CD209 CLEC4L KIAA0568 PPL XDH XDHA
Ligand-receptor interactions	Brother of CDO Cell adhesion molecule-related/down-regulated by oncogenes Desert hedgehog protein Growth arrest-specific protein 1 Hedgehog-interacting protein Indian hedgehog protein Protein patched homolog 1 Sonic hedgehog protein	O43323 P54826 Q13635 Q14623 Q15465 Q4KMG0 Q96QV1 Q9BWV1	BOC CDO CDON DHH GAS1 HHIP HIP IHH PTCH PTCH1 SHH
RUNX3 regulates p14-ARF	Bromodomain-containing protein 2 Core-binding factor subunit beta G1/S-specific cyclin-D1 GTPase KRas Histone acetyltransferase p300 Histone deacetylase 4 Runt-related transcription factor 1 Runt-related transcription factor 3 Transforming growth factor beta-1 proprotein	P01116 P01137 P24385 P25440 P56524 Q01196 Q09472 Q13761 Q13951	AML1 AML2 BCL1 BRD2 CBFA2 CBFA3 CBFB CCND1 EP300 HDAC4 KIAA0288 KIAA9001 KRAS KRAS2 P300 PEBP2A3 PRAD1 RASK2 RING3 RUNX1 RUNX3 TGFB TGFB1
Chromatin modifying enzymes	Bromodomain and WD repeat-containing protein 1 Histone H3.1 Histone H3.2 Protein-arginine deiminase type-1 Protein-arginine deiminase type-2 Protein-arginine deiminase type-3 Protein-arginine deiminase type-4 Protein-arginine deiminase type-6 Transcription activator BRG1	P51532 P68431 Q6TGC4 Q71DI3 Q9NSI6 Q9ULC6 Q9ULW8 Q9UM07 Q9Y2J8	BAF190A BRG1 BRWD1 C21orf107 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A HIST2H3C HIST2H3D KIAA0994 PAD1 PAD2 PAD3 PAD4 PAD6 PADI1 PADI2 PADI3 PADI4 PADI5 PADI6 PDI1 PDI2 PDI3 PDI5 SMARCA4 SNF2B SNF2L4 WDR9
Interleukin-7 signaling	Bromodomain and WD repeat-containing protein 1 Cytokine receptor common subunit gamma Cytokine receptor-like factor 2 Cytokine-inducible SH2-containing protein Hepatocyte growth factor Histone H3.1 Histone H3.2 Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin-7 receptor subunit alpha Interleukin-7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 2 Thymic stromal lymphopoietin Transcription activator BRG1 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3 V(D)J recombination-activating protein 1 V(D)J recombination-activating protein 2	O00459 O14508 O15524 P13232 P14210 P15918 P16871 P23458 P27986 P31785 P35568 P40763 P42229 P51532 P51692 P52333 P55895 P68431 Q71DI3 Q92569 Q969D9 Q9HC73 Q9NSE2 Q9NSI6 Q9Y4H2	APRF BAF190A BRG1 BRWD1 C21orf107 CIS2 CISH CRL2 CRLF2 G18 GRB1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM HGF HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A HIST2H3C HIST2H3D HPTA IL2RG IL7 IL7R ILXR IRS1 IRS2 JAK1 JAK1A JAK1B JAK3 PIK3R1 PIK3R2 PIK3R3 RAG1 RAG2 RNF74 SMARCA4 SNF2B SNF2L4 SOCS1 SOCS2 SSI1 SSI2 STAT3 STAT5 STAT5A STAT5B STATI2 TIP3 TSLP TSLPR WDR9
Regulation of TP53 Activity through Acetylation	Bromodomain and PHD finger-containing protein 3 Bromodomain-containing protein 1 Bromodomain-containing protein 7 Cellular tumor antigen p53 Chromatin modification-related protein MEAF6 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Histone acetyltransferase KAT6A Histone acetyltransferase p300 Histone deacetylase 1 Histone deacetylase 2 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Inhibitor of growth protein 5 Metastasis-associated protein MTA2 Methyl-CpG-binding domain protein 3 Peregrin Protein PML RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transcriptional repressor p66-alpha Transcriptional repressor p66-beta	O94776 O95696 O95983 P04637 P29590 P31749 P31751 P55201 Q09028 Q09472 Q12873 Q13547 Q14839 Q16576 Q86YP4 Q8WXI9 Q8WYH8 Q92769 Q92794 Q9HAF1 Q9NPI1 Q9ULD4 Q9Y243	AKT1 AKT2 AKT3 BP75 BR140 BRD1 BRD7 BRL BRPF1 BRPF2 BRPF3 C1orf149 CELTIX1 CENP-28 CHD3 CHD4 EAF6 EP300 GATAD2A GATAD2B HDAC1 HDAC2 ING5 KAT6A KIAA1150 KIAA1286 MBD3 MEAF6 MOZ MTA1L1 MTA2 MYL MYST3 P300 P53 PID PKB PKBG PML PP8675 RAC RBAP46 RBAP48 RBBP4 RBBP7 RNF71 RPD3L1 RUNXBP2 TP53 TRIM19 ZNF220
Iron uptake and transport	Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceruloplasmin Cullin-1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase F-box/LRR-repeat protein 5 Ferritin heavy chain Ferritin light chain Ferritin, mitochondrial Glutaredoxin-3 Heme oxygenase 1 Heme oxygenase 2 Hephaestin Iron-responsive element-binding protein 2 NEDD8 Natural resistance-associated macrophage protein 2 Neutrophil gelatinase-associated lipocalin Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-B Polyubiquitin-C Proton-coupled folate transporter S-phase kinase-associated protein 1 Serotransferrin Solute carrier family 22 member 17 Solute carrier family 40 member 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O76003 P00450 P02787 P02792 P02794 P09601 P0CG47 P0CG48 P21399 P30519 P48200 P49281 P62979 P62987 P63208 P80188 Q13616 Q15843 Q53TN4 Q86VP6 Q8N4E7 Q8WUG5 Q96NT5 Q9BQS7 Q9NP59 Q9UKA1 Q9UNQ0	ABCG2 ABCP ACO1 BCRP BCRP1 BOCT BOIT CAND1 CP CUL1 CYBRD1 DCT1 DCYTB DMT1 EMC19 FBL4 FBL5 FBXL5 FLR1 FPN FPN1 FRRS3 FTH FTH1 FTHL6 FTL FTMT G21 GLRX3 HCP1 HEPH HMOX1 HMOX2 HNL HO HO1 HO2 IREB1 IREB2 IREG1 KIAA0698 KIAA0829 LCN2 MXR NEDD8 NGAL NRAMP2 OCP2 PCFT PICOT RPS27A SKP1 SKP1A SLC11A2 SLC11A3 SLC22A17 SLC40A1 SLC46A1 TCEB1L TF TIP120 TIP120A TXNL2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	Bridging integrator 2 Golgin subfamily A member 4 KN motif and ankyrin repeat domain-containing protein 1 Transcription factor ETV6 Vascular endothelial growth factor receptor 2	P35968 P41212 Q13439 Q14678 Q9UBW5	ANKRD15 BIN2 BRAP1 ETV6 FLK1 GOLGA4 KANK KANK1 KDR KIAA0172 TEL TEL1 VEGFR2
HDR through MMEJ (alt-NHEJ)	Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA ligase 3 DNA polymerase theta DNA repair protein RAD50 DNA repair protein RAD52 homolog DNA repair protein XRCC1 Double-strand break repair protein MRE11 Flap endonuclease 1 Nibrin Poly [ADP-ribose] polymerase 1 Poly [ADP-ribose] polymerase 2	O60934 O75417 P09874 P18887 P39748 P43351 P49916 P49959 P51587 Q92878 Q99708 Q9UGN5	ADPRT ADPRT2 ADPRTL2 BRCA2 CTIP FACD FANCD1 FEN1 HNGS1 LIG3 MRE11 MRE11A NBN NBS NBS1 P95 PARP1 PARP2 POLH POLQ PPOL RAD2 RAD50 RAD52 RBBP8 XRCC1
TP53 Regulates Transcription of DNA Repair Genes	Breast cancer type 1 susceptibility protein CDK-activating kinase assembly factor MAT1 Cellular tumor antigen p53 Cyclic AMP-dependent transcription factor ATF-2 Cyclin-H Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 12 Cyclin-dependent kinase 13 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA damage-binding protein 2 DNA mismatch repair protein Mlh1 DNA mismatch repair protein Msh2 DNA repair protein RAD51 homolog 4 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 Fanconi anemia group C protein Fanconi anemia group D2 protein Fanconi anemia group I protein General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Mediator of DNA damage checkpoint protein 1 Mismatch repair endonuclease PMS2 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Protein c-Fos RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription factor Jun	O00267 O14757 O15514 O60563 O60583 O75771 O75909 P01100 P04637 P05412 P13984 P15336 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P38398 P40692 P43246 P50613 P50750 P51946 P51948 P52434 P52435 P53803 P54278 P55199 P61218 P62487 P62875 P63272 Q00597 Q08945 Q13315 Q13535 Q13888 Q13889 Q14004 Q14241 Q14676 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92466 Q92759 Q9BXW9 Q9H3P2 Q9NVI1 Q9NYV4 Q9Y5B0 Q9Y5B9	ATF2 ATM ATR BRCA1 BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CCNH CCNK CCNT1 CCNT2 CDC2L CDC2L4 CDC2L5 CDK12 CDK13 CDK7 CDK9 CDKN7 CHED CHEK1 CHK1 COBRA1 COCA2 CPR4 CREB2 CREBP1 CRK7 CRKRS CTDP1 DDB2 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FAC FACC FACD FACT140 FACT80 FACTP140 FANCC FANCD2 FANCI FCP1 FOS FRP1 G0S7 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S JUN KIAA0170 KIAA0904 KIAA1182 KIAA1791 KIAA1794 MAT1 MDC1 MLH1 MNAT1 MO15 MSH2 NELFA NELFB NELFCD NELFD NELFE NFBD1 P53 PMS2 PMSL2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAD51D RAD51L3 RAP30 RAP74 RD RDBP RNF53 RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TP53 TTDA WHSC2 XPB XPBC XPD XPDC
Meiotic recombination	Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 DNA endonuclease RBBP8 DNA mismatch repair protein Mlh1 DNA mismatch repair protein Mlh3 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 3 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.1t Histone H3.2 Histone H3.3 Histone H4 Histone-lysine N-methyltransferase PRDM9 Homologous-pairing protein 2 homolog Meiotic nuclear division protein 1 homolog Meiotic recombination protein DMC1/LIM15 homolog Meiotic recombination protein SPO11 MutS protein homolog 4 MutS protein homolog 5 Nibrin RecQ-like DNA helicase BLM Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Testis-expressed protein 15	O15457 O43196 O43502 O60814 O60934 P04908 P06899 P0C5Y9 P11802 P15927 P16104 P20671 P23527 P24941 P27694 P33778 P35244 P38398 P40692 P49959 P51587 P54132 P57053 P58876 P62805 P62807 P68431 P84243 Q06609 Q13315 Q13472 Q14565 Q16695 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q92878 Q93077 Q93079 Q96A08 Q99708 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9BWT6 Q9BXT5 Q9NQV7 Q9P2W1 Q9UHC1 Q9Y5K1	ATM BLM BRCA1 BRCA2 CDK2 CDK4 CDKN2 COCA2 CTIP DMC1 DMC1H FACD FANCD1 GAJ H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3-4 H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 HNGS1 HOP2 LIM15 MLH1 MLH3 MND1 MRE11 MRE11A MSH4 MSH5 NBN NBS NBS1 P95 PFM6 PRDM9 PSMC3IP RAD50 RAD51 RAD51A RAD51C RAD51L2 RBBP8 RECA RECQ2 RECQL3 REPA1 REPA2 REPA3 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 SPO11 TBPIP TEX15 TOP3 TOP3A TSH2B
Signaling by cytosolic FGFR1 fusion mutants	Breakpoint cluster region protein Centrosomal protein 43 Cleavage and polyadenylation specificity factor subunit 6 FGFR1 oncogene partner 2 GRB2-associated-binding protein 2 Homeobox protein cut-like 1 Leucine-rich repeat flightless-interacting protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Transcription intermediary factor 1-alpha Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	O15164 O95684 P11274 P27986 P39880 P40763 P42224 P42229 P42336 P51692 Q16630 Q32MZ4 Q92614 Q9NVK5 Q9UBW7 Q9UQC2	APRF BCR BCR1 CD245 CEP43 CFIM68 CPSF6 CUTL1 CUX1 D22S11 FGFR1OP FGFR1OP2 FIM FOP GAB2 GCF2 GRB1 KIAA0216 KIAA0571 LRRFIP1 MYO18A MYSPDZ PIK3CA PIK3R1 RAMP RNF82 STAT1 STAT3 STAT5 STAT5A STAT5B TIAF1 TIF1 TIF1A TRIM24 TRIP ZMYM2 ZNF198
MECP2 regulates transcription of neuronal ligands	Brain-derived neurotrophic factor Corticoliberin Delta-like protein 1 Histone deacetylase 1 Paired amphipathic helix protein Sin3a Somatostatin	O00548 P06850 P23560 P61278 Q13547 Q96ST3	BDNF CRH DLL1 HDAC1 RPD3L1 SIN3A SST
The fatty acid cycling model	Brain mitochondrial carrier protein 1 Dicarboxylate carrier SLC25A8 Mitochondrial brown fat uncoupling protein 1 Mitochondrial uncoupling protein 4 Putative mitochondrial transporter UCP3	O95258 O95847 P25874 P55851 P55916	BMCP1 SLC25A14 SLC25A27 SLC25A7 SLC25A8 SLC25A9 UCP UCP1 UCP2 UCP3 UCP4 UCP5
The proton buffering model	Brain mitochondrial carrier protein 1 Dicarboxylate carrier SLC25A8 Mitochondrial brown fat uncoupling protein 1 Mitochondrial uncoupling protein 4 Putative mitochondrial transporter UCP3	O95258 O95847 P25874 P55851 P55916	BMCP1 SLC25A14 SLC25A27 SLC25A7 SLC25A8 SLC25A9 UCP UCP1 UCP2 UCP3 UCP4 UCP5
Toxicity of botulinum toxin type G (botG)	Botulinum neurotoxin type G Synaptotagmin-1 Vesicle-associated membrane protein 1 Vesicle-associated membrane protein 2	P21579 P23763 P63027 Q60393	SVP65 SYB1 SYB2 SYT SYT1 VAMP1 VAMP2 botG
Toxicity of botulinum toxin type F (botF)	Botulinum neurotoxin type F Synaptic vesicle glycoprotein 2A Synaptic vesicle glycoprotein 2B Synaptic vesicle glycoprotein 2C Vesicle-associated membrane protein 1 Vesicle-associated membrane protein 2	P23763 P30996 P63027 Q496J9 Q7L0J3 Q7L1I2	KIAA0735 KIAA0736 KIAA1054 SV2A SV2B SV2C SYB1 SYB2 VAMP1 VAMP2 botF
Toxicity of botulinum toxin type E (botE)	Botulinum neurotoxin type E NTNHA Synaptic vesicle glycoprotein 2A Synaptic vesicle glycoprotein 2B Synaptosomal-associated protein 25	P60880 Q00496 Q7L0J3 Q7L1I2 Q9LBS8	KIAA0735 KIAA0736 SNAP SNAP25 SV2A SV2B botE ntnha

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