GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Lysosomal oligosaccharide catabolism	Alpha-mannosidase 2C1 Beta-mannosidase Epididymis-specific alpha-mannosidase Lysosomal alpha-mannosidase	O00462 O00754 Q9NTJ4 Q9Y2E5	KIAA0935 LAMAN MAN2B1 MAN2B2 MAN2C1 MANA MANA1 MANB MANB1 MANBA	Homo sapiens (human)	G00027MO G25577BM G28233ME G70323CJ G90333CG
Glyoxylate metabolism and glycine degradation	2-Hydroxyacid oxidase 1 4-hydroxy-2-oxoglutarate aldolase, mitochondrial Alanine--glyoxylate aminotransferase 2, mitochondrial Alanine--glyoxylate aminotransferase Aspartate aminotransferase, mitochondrial D-amino-acid oxidase D-aspartate oxidase Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial Glycine N-methyltransferase Glyoxylate reductase/hydroxypyruvate reductase Hydroxyproline dehydrogenase Peroxisomal membrane protein 2	P00505 P14920 P21549 P30038 Q14749 Q86XE5 Q99489 Q9BYV1 Q9NR77 Q9UBQ7 Q9UF12 Q9UJM8	AGT1 AGT2 AGXT AGXT2 ALDH4 ALDH4A1 C10orf65 DAMOX DAO DDO DHDPSL GLXR GNMT GOT2 GOX1 GRHPR HAO1 HOGA1 HSPOX1 HYPDH KYAT4 P5CDH PMP22 PRODH2 PXMP2 SPAT	Homo sapiens (human)
Signaling by FGFR4 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1	P01111 P01112 P19174 P22455 P27986 P42336 Q07889 Q13480 Q8WU20	FGFR4 FRS2 GAB1 GRB1 HRAS HRAS1 JTK2 NRAS PIK3CA PIK3R1 PLC1 PLCG1 SOS1 TKF	Homo sapiens (human)
Aryl hydrocarbon receptor signalling	AH receptor-interacting protein Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Heat shock protein HSP 90-beta Prostaglandin E synthase 3	A9YTQ3 O00170 P08238 P27540 P35869 Q15185 Q9HBZ2	AHR AHRR AIP ARNT ARNT2 BHLHE1 BHLHE2 BHLHE76 BHLHE77 HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KIAA0307 KIAA1234 P23 PTGES3 TEBP XAP2	Homo sapiens (human)
Kandutsch-Russell pathway	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7-dehydrocholesterol reductase Delta(24)-sterol reductase Lathosterol oxidase	O75845 Q15125 Q15392 Q9UBM7	D7SR DHCR24 DHCR7 EBP KIAA0018 SC5D SC5DL	Homo sapiens (human)
Replication of the SARS-CoV-2 genome	Probable ATP-dependent RNA helicase DDX5 Replicase polyprotein 1a Replicase polyprotein 1ab Retinoblastoma-associated protein Zinc finger CCHC-type and RNA-binding motif-containing protein 1 von Hippel-Lindau disease tumor suppressor	P06400 P0DTC1 P0DTD1 P17844 P40337 Q8TBF4	DDX5 G17P1 HELR HLR1 RB1 VHL ZCRB1 rep	Homo sapiens (human)
Eukaryotic Translation Termination	Acylamino-acid-releasing enzyme Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Eukaryotic peptide chain release factor GTP-binding subunit ERF3B Eukaryotic peptide chain release factor subunit 1 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Methyltransferase N6AMT1 Multifunctional methyltransferase subunit TRM112-like protein Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P05386 P05387 P05388 P08708 P08865 P13798 P15170 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P39019 P39023 P40429 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P50914 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62495 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q6P5R6 Q71UM5 Q8IYD1 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q9UI30 Q9UNX3 Q9Y3U8 Q9Y5N5	APEH BBC1 C21orf127 CCG2 D11S2243E D3F15S2 D3S48E D6S218E DNF15S2 DXS648E EC45 ERF1 ERF3A ERF3B ETF1 FAU FTE1 GSPT1 GSPT2 HEMK2 KMT9 LAMBR LAMR1 MFTL MPS1 N6AMT1 NEDD6 PRED28 QM RF1 RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SUP45L1 SURF-3 SURF3 TRMT112 TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
The retinoid cycle in cones (daylight vision)	Acyl-CoA wax alcohol acyltransferase 2 Long-wave-sensitive opsin 1 Medium-wave-sensitive opsin 1 Retinaldehyde-binding protein 1 Retinol-binding protein 3 Short-chain dehydrogenase/reductase 3 Short-wave-sensitive opsin 1	O75911 P03999 P04000 P04001 P10745 P12271 Q6E213	AWAT2 BCP CRALBP DC4 DGAT2L4 DHRS3 GCP MFAT OPN1LW OPN1MW OPN1SW RBP3 RCP RDH17 RLBP1 SDR16C1 WS	Homo sapiens (human)
Surfactant metabolism	Adenosine deaminase 2 Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Cytokine receptor common subunit beta Cytoskeleton-associated protein 4 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha LIM and cysteine-rich domains protein 1 Napsin-A P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Pepsin A-3 Pepsin A-4 Pepsin A-5 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Scavenger receptor cysteine-rich domain-containing protein DMBT1 Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Surfactant-associated protein 3 Thyroid transcription factor 1-associated protein 26 Transcription factor GATA-6 Transcription termination factor 1	O95436 O96009 P07988 P08913 P09668 P0C7M3 P0DJD7 P0DJD8 P0DJD9 P11686 P15509 P18825 P29274 P29275 P32927 P35247 P41231 Q06495 Q07065 Q15361 Q8IWL1 Q8IWL2 Q8IZF2 Q92908 Q99758 Q9NZK5 Q9NZU5 Q9P031 Q9UGM3 Q9UIJ5	ABC3 ABCA3 ADA2 ADGF ADGRF5 ADORA2 ADORA2A ADORA2B ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR BR22 CCDC59 CECR1 CKAP4 COLEC4 COLEC5 COLEC7 CPSB CSF2R CSF2RA CSF2RB CSF2RY CTSH DMBT1 GATA6 GP340 GPR116 IDGFL IL3RB IL5RB KIAA0758 LMCD1 NAP1 NAPA NAPSA NPT2 P2RU1 P2RY2 PGA3 PGA4 PGA5 PSAP PSPD REAM REC SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH SLC17A2 SLC34A1 SLC34A2 TAP26 TTF1 ZDHHC2 ZNF372	Homo sapiens (human)
Pyroptosis	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Caspase-1 Caspase-3 Caspase-4 Caspase-5 Cellular tumor antigen p53 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c Gasdermin-D Gasdermin-E Granzyme B High mobility group protein B1 Interferon regulatory factor 1 Interferon regulatory factor 2 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Neutrophil elastase Tumor protein 63	O43633 O60443 P01583 P01584 P04637 P08246 P09429 P10144 P10914 P14316 P29466 P42574 P49662 P51878 P57764 P99999 Q07812 Q14116 Q16611 Q8WUX9 Q96CF2 Q96FZ7 Q9BY43 Q9H3D4 Q9H444 Q9UQN3 Q9Y3E7	BAK BAK1 BAX BC2 BCL2L4 BCL2L7 C14orf123 C20orf178 CASP1 CASP3 CASP4 CASP5 CDN1 CGI149 CGL1 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CPP32 CSPB CTLA1 CYC CYCS DFNA5 DFNA5L ELA2 ELANE GRB GSDMD GSDMDC1 GSDME GZMB HMG1 HMGB1 ICERE1 ICH2 ICH3 IGIF IL18 IL1A IL1B IL1BC IL1BCE IL1F1 IL1F2 IL1F4 IRF1 IRF2 KET NEDF P53 P63 P73H P73L SHAX1 SHAX2 SHAX3 TP53 TP63 TP73L VPS20 VPS24	Homo sapiens (human)
FCGR activation	High affinity immunoglobulin gamma Fc receptor I IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Low affinity immunoglobulin gamma Fc region receptor II-a Low affinity immunoglobulin gamma Fc region receptor III-A T-cell surface glycoprotein CD3 gamma chain Tyrosine-protein kinase Fgr Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07947 P07948 P08631 P08637 P09693 P09769 P0CF74 P0CG04 P0DOY2 P0DOY3 P12314 P12318 P23083 P43405 P80748 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0	CD16A CD32 CD3G FCG1 FCG2 FCG3 FCGR1 FCGR1A FCGR2A FCGR2A1 FCGR3 FCGR3A FGR FYN HCK IGFR1 IGFR2 IGFR3 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 JTK8 LYN SRC2 SYK T3G V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 YES YES1	Homo sapiens (human)
TRAF3 deficiency - HSE	TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 Toll-like receptor 3	O15455 Q13114 Q8IUC6	CAP-1 CRAF1 PRVTIRB TICAM1 TLR3 TRAF3 TRAFAMN TRIF	Homo sapiens (human)
Beta oxidation of hexanoyl-CoA to butanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P16219 P30084 P40939 P55084 Q16836	ACADS ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC SCHAD	Homo sapiens (human)
FLT3 Signaling	Bcl-2-like protein 11 Cyclin-dependent kinase inhibitor 1B Fms-related tyrosine kinase 3 ligand Forkhead box protein O3 GRB2-associated-binding protein 2 GRB2-related adapter protein 2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 10 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Receptor-type tyrosine-protein kinase FLT3 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43521 O43524 O75791 P01111 P01112 P27986 P31749 P31751 P36888 P42336 P46527 P49771 Q06124 Q07889 Q13322 Q9UQC2 Q9Y243	AKT1 AKT2 AKT3 BCL2L11 BIM CD135 CDKN1B FKHRL1 FLK2 FLT3 FLT3LG FOXO3 FOXO3A GAB2 GADS GRAP2 GRB1 GRB10 GRB2L GRBIR GRID HRAS HRAS1 KIAA0207 KIAA0571 KIP1 NRAS PIK3CA PIK3R1 PKB PKBG PTP2C PTPN11 RAC SHPTP2 SOS1 STK1 p27	Homo sapiens (human)
Nuclear events stimulated by ALK signaling in cancer	Bcl-2-related protein A1 CCAAT/enhancer-binding protein beta Cullin-1 DNA (cytosine-5)-methyltransferase 1 E3 ubiquitin-protein ligase RBX1 Forkhead box protein M1 G2/mitotic-specific cyclin-B1 Granzyme B Helicase MOV-10 Histone deacetylase 1 Inducible T-cell costimulator Interferon regulatory factor 4 Interleukin-10 receptor subunit alpha Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Nucleophosmin Perforin-1 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Retinoblastoma-associated protein S-phase kinase-associated protein 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Small ribosomal subunit protein eS6 Transcription factor JunB Trinucleotide repeat-containing gene 6C protein Twist-related protein 1 Tyrosine-protein kinase ZAP-70 Tyrosine-protein phosphatase non-receptor type 6 Zinc finger C3HC-type protein 1	P06400 P06748 P10144 P14222 P14635 P17275 P17676 P26358 P27361 P28482 P29350 P40763 P42229 P43403 P62753 P62877 P63208 Q08050 Q13547 Q13616 Q13651 Q15306 Q15672 Q16548 Q86WB0 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9Y6W8	AGO1 AGO2 AGO3 AGO4 AILIM AIM APRF BCL2A1 BCL2L5 BFL1 BHLHA38 CCNB CCNB1 CEBPB CGL1 CSPB CTLA1 CUL1 CXXC9 DNMT DNMT1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 EMC19 ERK1 ERK2 FKHL16 FOXM1 GRB GRS GZMB HBPA1 HCP HDAC1 HFH11 ICOS IL10R IL10RA IRF4 JUNB KIAA1567 KIAA1582 KIAA1631 MAPK1 MAPK3 MOV10 MPP2 MUM1 NIPA NPM NPM1 OCP2 PFP PRF1 PRKM1 PRKM2 PRKM3 PTP1C PTPN6 RB1 RBX1 RNF75 ROC1 RPD3L1 RPS6 SKP1 SKP1A SRK STAT3 STAT5 STAT5A TCEB1L TCF5 TNRC6C TWIST TWIST1 WIN ZAP70 ZC3HC1	Homo sapiens (human)
Recognition of DNA damage by PCNA-containing replication complex	Cullin-4A Cullin-4B DNA damage-binding protein 1 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 Denticleless protein homolog E3 ubiquitin-protein ligase RAD18 E3 ubiquitin-protein ligase RBX1 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Ubiquitin carboxyl-terminal hydrolase 1 Ubiquitin-conjugating enzyme E2 B Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 48	O94782 P0CG47 P0CG48 P12004 P15927 P27694 P28340 P35244 P35249 P35250 P35251 P40937 P40938 P49005 P56282 P62877 P62979 P62987 P63146 Q07864 Q13619 Q13620 Q15054 Q16531 Q8TAF3 Q9HCU8 Q9NR33 Q9NRF9 Q9NS91 Q9NZJ0	CDT2 CDW1 CHRAC17 CUL4A CUL4B DCAF2 DDB1 DPE2 DTL KIAA0039 KIAA0695 KIAA1449 L2DTL PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 RAD18 RAD6B RAMP RBX1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF73 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH1 UBE2B USP1 WDR48 XAP1	Homo sapiens (human)
Signalling to STAT3	Beta-nerve growth factor High affinity nerve growth factor receptor Signal transducer and activator of transcription 3	P01138 P04629 P40763	APRF MTC NGF NGFB NTRK1 STAT3 TRK TRKA	Homo sapiens (human)
NOTCH2 intracellular domain regulates transcription	Granzyme B Histone acetyltransferase p300 Low affinity immunoglobulin epsilon Fc receptor Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Neurogenic locus notch homolog protein 2 Recombining binding protein suppressor of hairless Transcription factor HES-1 Transcription factor HES-5	P06734 P10144 Q04721 Q06330 Q09472 Q13495 Q14469 Q5TA89 Q8IZL2 Q92585 Q96JK9	BHLHB38 BHLHB39 CD23A CG1 CGL1 CLEC4J CSPB CTLA1 CXorf6 EP300 FCE2 FCER2 GRB GZMB HES1 HES5 HL HRY IGEBF IGKJRB IGKJRB1 KIAA0200 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 NOTCH2 P300 RBPJ RBPJK RBPSUH	Homo sapiens (human)
Gap-filling DNA repair synthesis and ligation in TC-NER	CDK-activating kinase assembly factor MAT1 Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA excision repair protein ERCC-6 DNA excision repair protein ERCC-8 DNA ligase 1 DNA ligase 3 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair protein XRCC1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Peptidyl-prolyl cis-trans isomerase E Polyubiquitin-B Polyubiquitin-C Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor SYF1 Proliferating cell nuclear antigen RNA helicase aquarius Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Transcription elongation factor A protein 1 UV-stimulated scaffold protein A Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein 830	O15514 O60306 P0CG47 P0CG48 P12004 P15927 P18074 P18858 P18887 P19387 P19388 P19447 P23193 P24928 P27694 P28340 P30876 P32780 P35244 P35249 P35250 P35251 P36954 P40937 P40938 P49005 P49916 P50613 P51946 P51948 P52434 P52435 P53803 P56282 P61218 P62487 P62875 P62877 P62979 P62987 Q03468 Q07864 Q13216 Q13619 Q13620 Q13888 Q13889 Q15054 Q16531 Q2YD98 Q6ZYL4 Q92759 Q93009 Q96NB3 Q9HCS7 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9ULR0 Q9UMS4 Q9UNP9	AQR BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCDC16 CCNH CDK7 CDKN7 CHRAC17 CKN1 CSA CSB CUL4A CUL4B CYP33 DDB1 DINB1 DPE2 ERCC2 ERCC3 ERCC6 ERCC8 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HAUSP HCNP ISY1 KIAA0039 KIAA0560 KIAA0695 KIAA1160 KIAA1177 KIAA1530 LIG1 LIG3 MAT1 MNAT1 MO15 NMP200 PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLK POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PRP19 PRPF19 RBX1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF66 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPB7 RPS27A SNEV STK1 SYF1 TCEA1 TFIIS TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 UVSSA XAB2 XAP1 XPB XPBC XPD XPDC XRCC1 ZNF830	Homo sapiens (human)
Scavenging by Class F Receptors	Apolipoprotein B-100 Calreticulin Heat shock protein 105 kDa Heat shock protein HSP 90-alpha Hypoxia up-regulated protein 1 Major outer membrane protein P.IB Scavenger receptor class F member 1	P04114 P07900 P18195 P27797 Q14162 Q92598 Q9Y4L1	APOB CALR CRTC GRP170 HSP105 HSP110 HSP90A HSP90AA1 HSPC1 HSPCA HSPH1 HSPH4 HYOU1 KIAA0149 KIAA0201 ORP150 SCARF1 SREC porB	Homo sapiens (human)
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)	Ferroportin Hephaestin	Q9BQS7 Q9NP59	FPN FPN1 HEPH IREG1 KIAA0698 SLC11A3 SLC40A1	Homo sapiens (human)
RUNX3 Regulates Immune Response and Cell Migration	Core-binding factor subunit beta Integrin alpha-4 Integrin alpha-L Osteopontin Runt-related transcription factor 3	P10451 P13612 P20701 Q13761 Q13951	AML2 BNSP CBFA3 CBFB CD11A CD49D ITGA4 ITGAL OPN PEBP2A3 RUNX3 SPP1	Homo sapiens (human)
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	Acid ceramidase V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit E 1 V-type proton ATPase subunit G 1 V-type proton ATPase subunit H V-type proton ATPase subunit d 1 V-type proton ATPase subunit e 1	O15342 O75348 P21281 P21283 P27449 P36543 P38606 P61421 Q13510 Q99437 Q9UI12	ASAH ASAH1 ATP6A1 ATP6B2 ATP6C ATP6D ATP6E ATP6E2 ATP6F ATP6G ATP6G1 ATP6H ATP6J ATP6L ATP6V0B ATP6V0C ATP6V0D1 ATP6V0E ATP6V0E1 ATP6V1A ATP6V1A1 ATP6V1B2 ATP6V1C1 ATP6V1E1 ATP6V1G1 ATP6V1H ATPL VATC VPATPD VPP2 VPP3	Homo sapiens (human)
Polo-like kinase mediated events	Centromere protein F Forkhead box protein M1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Histone acetyltransferase p300 Histone-binding protein RBBP4 M-phase inducer phosphatase 1 M-phase inducer phosphatase 3 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Myb-related protein B Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Serine/threonine-protein kinase PLK1 Wee1-like protein kinase	O95067 P10244 P14635 P30291 P30304 P30307 P49454 P53350 Q08050 Q09028 Q09472 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3 Q99640	BARA BMYB C14orf46 CCNB CCNB1 CCNB2 CDC25A CDC25C CENPF CXCDC1 EP300 FKHL16 FOXM1 HFH11 KIAA2037 LIN37 LIN52 LIN54 LIN9 MPP2 MYBL2 MYT1 P300 PKMYT1 PLK PLK1 RBAP48 RBBP4 TGS WEE1 WIN	Homo sapiens (human)
Propionyl-CoA catabolism	Methylmalonic aciduria type A protein, mitochondrial Methylmalonyl-CoA epimerase, mitochondrial Methylmalonyl-CoA mutase, mitochondrial Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial	P05165 P05166 P22033 Q8IVH4 Q96PE7	MCEE MMAA MMUT MUT PCCA PCCB	Homo sapiens (human)

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