GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **601 - 625** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Lysosome Vesicle Biogenesis	ADP-ribosylation factor 1 AP-1 complex subunit beta-1 AP-1 complex subunit gamma-1 AP-1 complex subunit gamma-like 2 AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-1 complex subunit sigma-3 AP-4 complex subunit beta-1 AP-4 complex subunit epsilon-1 AP-4 complex subunit mu-1 AP-4 complex subunit sigma-1 Amyloid-beta precursor protein Auxilin Beta-arrestin-1 Biogenesis of lysosome-related organelles complex 1 subunit 1 Cathepsin Z Cation-dependent mannose-6-phosphate receptor Charged multivesicular body protein 2a Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Clavesin-1 Clavesin-2 Deoxyribonuclease-2-alpha Dynamin-2 Endophilin-A1 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate N-acetylglucosamine-6-sulfatase Thioredoxin domain-containing protein 5 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	O00115 O00189 O14964 O43633 O43747 O75061 O75843 P05067 P09496 P09497 P11142 P15586 P20645 P49407 P50570 P51809 P56377 P61966 P63027 P78537 P84077 Q00610 Q10567 Q5SYC1 Q8IUQ0 Q8NBS9 Q96PC3 Q99962 Q9BV40 Q9BXS5 Q9UBR2 Q9UPM8 Q9Y587 Q9Y6B7 Q9Y6Q5	A4 AD1 ADTB1 ADTG AP19 AP1B1 AP1G1 AP1G2 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP4B1 AP4E1 AP4M1 AP4S1 APP ARF1 ARR1 ARRB1 BAM22 BC2 BLOC1S1 BLOS1 C6orf212 C6orf213 CHMP2 CHMP2A CLAPB2 CLAPG1 CLAPS1 CLH17 CLTA CLTB CLTC CLTCL2 CLTNM CLVS1 CLVS2 CNSA2 CRALBPL CTSZ DNAJC6 DNASE2 DNASE2A DNL2 DNM2 DYN2 GCN5L1 GNS HGS HRS HSC70 HSP73 HSPA10 HSPA8 KIAA0034 KIAA0473 M6PR MPR46 MPRD MUARP2 RLBP1L1 RLBP1L2 RT14 SH3D2A SH3GL2 SYB2 SYBL1 TLP46 TXNDC5 VAMP2 VAMP7 VAMP8	Homo sapiens (human)
Purine catabolism	5'(3')-deoxyribonucleotidase, cytosolic type 5'-nucleotidase 5-hydroxymethyl-dUMP N-hydrolase Cytosolic 5'-nucleotidase 1A Cytosolic 5'-nucleotidase 1B Cytosolic purine 5'-nucleotidase Guanine deaminase Inosine triphosphate pyrophosphatase Purine nucleoside phosphorylase Xanthine dehydrogenase/oxidase	O43598 P00491 P21589 P47989 P49902 Q8TCD5 Q96P26 Q9BXI3 Q9BY32 Q9Y2T3	AIRP C20orf37 C6orf108 DNPH1 DNT1 GDA ITPA KIAA1258 NP NT5 NT5B NT5C NT5C1A NT5C1B NT5C2 NT5CP NT5E NTE PNP PNT5 RCL UMPH2 XDH XDHA	Homo sapiens (human)
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Apoptosis facilitator Bcl-2-like protein 14 Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 B-cell lymphoma 6 protein Baculoviral IAP repeat-containing protein 5 Cellular tumor antigen p53 Geranylgeranyl transferase type-2 subunit alpha Geranylgeranyl transferase type-2 subunit beta Protein NDRG1 Quinone oxidoreductase PIG3 Rab proteins geranylgeranyltransferase component A 1 Tumor protein 63 Tumor protein p73 p53 apoptosis effector related to PMP-22	O15350 O15392 P04637 P24386 P41182 P53611 Q13625 Q53FA7 Q92597 Q92696 Q96FX8 Q96KQ4 Q9BZR8 Q9H3D4	API4 ASPP1 ASPP2 BBP BCL2L14 BCL5 BCL6 BCLG BIRC5 CAP43 CHM DRG1 GGTB IAP4 KCP1 KET KIAA0771 KRTCAP1 LAZ3 NDRG1 P53 P63 P73 P73H P73L PERP PIG3 PIGPC1 PPP1R13B RABGGTA RABGGTB REP1 RTP TCD THW TP53 TP53BP2 TP53I3 TP63 TP73 TP73L ZBTB27 ZNF51	Homo sapiens (human)
Abacavir transmembrane transport	ATP-dependent translocase ABCB1 Broad substrate specificity ATP-binding cassette transporter ABCG2 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	O15244 O15245 O75751 P08183 Q9UNQ0	ABCB1 ABCG2 ABCP BCRP BCRP1 EMTH MDR1 MXR OCT1 OCT2 OCT3 PGY1 SLC22A1 SLC22A2 SLC22A3	Homo sapiens (human)
Metal sequestration by antimicrobial proteins	Lactotransferrin Neutrophil gelatinase-associated lipocalin Protein S100-A7 Protein S100-A7A Protein S100-A8 Protein S100-A9	P02788 P05109 P06702 P31151 P80188 Q86SG5	CAGA CAGB CFAG GIG12 HNL LCN2 LF LTF MRP14 MRP8 NGAL PSOR1 S100A15 S100A7 S100A7A S100A7C S100A7L1 S100A8 S100A9	Homo sapiens (human)
PKA activation in glucagon signalling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q5JWF2 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAS GNAS1 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1	Homo sapiens (human)
Inactivation of CDC42 and RAC1	Cell division control protein 42 homolog Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 39 Roundabout homolog 1 SLIT-ROBO Rho GTPase-activating protein 1 SLIT-ROBO Rho GTPase-activating protein 2 SLIT-ROBO Rho GTPase-activating protein 3 Slit homolog 2 protein	O43295 O75044 O94813 P60953 P63000 Q7Z6B7 Q9C0H5 Q9Y6N7	ARHGAP13 ARHGAP14 ARHGAP34 ARHGAP39 CDC42 DUTT1 FNBP2 KIAA0411 KIAA0456 KIAA1156 KIAA1304 KIAA1688 MEGAP RAC1 ROBO1 SLIL3 SLIT2 SRGAP1 SRGAP2 SRGAP2A SRGAP3 TC25	Homo sapiens (human)
Enzymatic degradation of dopamine by COMT	Amine oxidase [flavin-containing] A Catechol O-methyltransferase Transmembrane O-methyltransferase	P21397 P21964 Q8WZ04	COMT COMT2 LRTOMT MAOA TOMT	Homo sapiens (human)
Packaging of Eight RNA Segments	Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821	HA M NA NP NS PA PB1 PB2	Homo sapiens (human)
Activation of NIMA Kinases NEK9, NEK6, NEK7	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Serine/threonine-protein kinase Nek6 Serine/threonine-protein kinase Nek7 Serine/threonine-protein kinase Nek9 Serine/threonine-protein kinase PLK1	O95067 P06493 P14635 P53350 Q8TD19 Q8TDX7 Q9HC98	CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 KIAA1995 NEK6 NEK7 NEK8 NEK9 NERCC P34CDC2 PLK PLK1	Homo sapiens (human)
RIPK1-mediated regulated necrosis	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase-8 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Flotillin-1 Flotillin-2 Mixed lineage kinase domain-like protein Non-structural protein 1 Programmed cell death 6-interacting protein Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 Ribonucleoside-diphosphate reductase large subunit Syntenin-1 TNF receptor-associated factor 2 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	O00220 O00560 O14763 O15294 O75955 P03496 P08543 P25445 P48023 P50591 P98170 Q12933 Q13158 Q13489 Q13490 Q13546 Q14254 Q14790 Q15628 Q8NB16 Q8WUM4 Q9UNE7 Q9Y572	AIP1 ALIX API1 API2 API3 APO2 APO2L APT1 APT1LG1 BIRC2 BIRC3 BIRC4 CASP8 CD95L CHIP DR4 DR5 ESA1 FADD FAS FAS1 FASL FASLG FLOT1 FLOT2 IAP3 ICP6 KIAA1375 KILLER M17S1 MCH5 MDA9 MIHB MIHC MLKL MORT1 NS OGT PDCD6IP RIP RIP1 RIP3 RIPK1 RIPK3 RIR1 RNF48 RNF49 SDCBP STUB1 SYCL TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAP3 TRICK2 XIAP ZTNFR9	Homo sapiens (human)
Degradation of cysteine and homocysteine	2-aminoethanethiol dioxygenase 3-mercaptopyruvate sulfurtransferase Acidic amino acid decarboxylase GADL1 Aspartate aminotransferase, mitochondrial Cystathionine gamma-lyase Cysteine dioxygenase type 1 Cysteine sulfinic acid decarboxylase Flavin-containing monooxygenase 1 Thioredoxin, mitochondrial Thiosulfate sulfurtransferase	P00505 P25325 P32929 Q01740 Q16762 Q16878 Q6ZQY3 Q96SZ5 Q99757 Q9Y600	ADO C10orf22 CDO1 CSAD CSD CTH FMO1 GADL1 GOT2 KYAT4 MPST TRX2 TST TST2 TXN2	Homo sapiens (human)
Nitric oxide stimulates guanylate cyclase	Guanylate cyclase soluble subunit alpha-1 Guanylate cyclase soluble subunit alpha-2 Guanylate cyclase soluble subunit beta-1 Guanylate cyclase soluble subunit beta-2 Nitric oxide synthase 1 Nitric oxide synthase 3 Nitric oxide synthase, inducible	O75343 P29474 P29475 P33402 P35228 Q02108 Q02153	GUC1A2 GUC1A3 GUC1B3 GUCSA2 GUCSA3 GUCSB3 GUCY1A1 GUCY1A2 GUCY1A3 GUCY1B1 GUCY1B2 GUCY1B3 NOS1 NOS2 NOS2A NOS3	Homo sapiens (human)
Regulation of TNFR1 signaling	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CAP-Gly domain-containing linker protein 3 Caspase-8 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase subunit epsilon MAP kinase-activated protein kinase 2 NF-kappa-B essential modulator OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin Polyubiquitin-B Polyubiquitin-C RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Serine proteinase inhibitor 2 Serine proteinase inhibitor 2 Serine/threonine-protein kinase TBK1 Serine/threonine-protein kinase ULK1 Sharpin Signal peptide peptidase-like 2A Signal peptide peptidase-like 2B Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TNF receptor-associated factor 1 TNF receptor-associated factor 2 Tax1-binding protein 1 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin thioesterase otulin Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein UL36	O14920 O15111 O75385 O75604 P01375 P07385 P0CG47 P0CG48 P15059 P16767 P19438 P21580 P49137 P51668 P61077 P62837 P62979 P62987 P63244 P68036 P98170 Q12933 Q13077 Q13107 Q13158 Q13489 Q13490 Q13546 Q14164 Q14790 Q15628 Q5VV17 Q6GQQ9 Q86VP1 Q8TCT7 Q8TCT8 Q96AX9 Q96BN8 Q96CV9 Q96DZ5 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9UHD2 Q9UK80 Q9UM82 Q9UNE7 Q9Y6K9	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CASP8 CHIP CHUK CLIP3 CLIPR59 CYLD CYLD1 DUBA7 EBI6 FADD FAM105B FIP2 FIP3 GLC1E GNB2L1 HIP7 HYPL IAP3 IKBKB IKBKE IKBKG IKKA IKKB IKKE IKKI IMP3 IMP4 KIAA0151 KIAA0722 KIAA0757 KIAA0849 KIAA1532 MAPKAPK2 MCH5 MIB2 MIHB MIHC MORT1 NAK NEMO NRP OPG199 OPTN OTDC1 OTUD1 OTUD7B OTUD7C OTULIN PD1 PSL1 PSL2 PUBC1 RACK1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 RPS27A SFT SHARPIN SIPL1 SKD SPATA2 SPI-2 SPPL2A SPPL2B STUB1 T6BP TAX1BP1 TBK1 TCF16 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF1 TRAF2 TRAP3 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCE7 UBCE7IP3 UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBCH7 UBE2D1 UBE2D2 UBE2D3 UBE2L3 UBP41 UL36 ULK1 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA ZZANK1	Homo sapiens (human)
HSP90 chaperone cycle for SHRs	Actin-related protein 10 Alpha-centractin Androgen receptor Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 DnaJ homolog subfamily A member 1 DnaJ homolog subfamily A member 2 DnaJ homolog subfamily A member 4 DnaJ homolog subfamily B member 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Glucocorticoid receptor Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Mineralocorticoid receptor Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP5 Progesterone receptor Prostaglandin E synthase 3 Stress-induced-phosphoprotein 1	O00399 O14576 O43237 O60884 O75935 P04150 P06401 P07900 P08235 P08238 P0DMV8 P0DMV9 P10275 P11142 P25685 P31689 P31948 P34931 P47755 P47756 P52907 P54652 P61163 P63167 Q02790 Q13409 Q13451 Q13561 Q14203 Q14204 Q15185 Q8WW22 Q96FJ2 Q96KX2 Q9BTE1 Q9NZ32 Q9UJW0 Q9Y6G9	ACTR10 ACTR11 ACTR1A AIG6 AR ARP10 ARP11 CAPAA3 CAPZA1 CAPZA2 CAPZA3 CAPZB CPR3 CTRN1 DCTN1 DCTN2 DCTN22 DCTN3 DCTN4 DCTN5 DCTN50 DCTN6 DHC1 DHTR DLC1 DLC2 DNAJ1 DNAJ2 DNAJA1 DNAJA2 DNAJA4 DNAJB1 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 FKBP4 FKBP5 FKBP51 FKBP52 GRL GSG3 HDJ1 HDJ2 HDLC1 HIRIP4 HSC70 HSJ2 HSP72 HSP73 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSPC1 HSPC2 HSPC3 HSPCA HSPCB HSPF1 HSPF4 HSX70 KIAA0325 LIC2 MCR MLR NR3C1 NR3C2 NR3C3 NR3C4 P23 PGR PTGES3 STIP1 TEBP WS3	Homo sapiens (human)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Fructosamine-3-kinase Ketosamine-3-kinase Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 1 Protein-tyrosine sulfotransferase 2	O60507 O60704 O60725 P00451 Q9H479 Q9HA64	F8 F8C FN3K FN3KRP ICMT PCCMT TPST1 TPST2	Homo sapiens (human)
CD209 (DC-SIGN) signaling	CD209 antigen CREB-binding protein GTPase HRas GTPase NRas Histone acetyltransferase p300 Intercellular adhesion molecule 2 Intercellular adhesion molecule 3 Nuclear factor NF-kappa-B p105 subunit RAF proto-oncogene serine/threonine-protein kinase Ribosomal protein S6 kinase alpha-5 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Transcription factor RelB Transcription factor p65 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O75582 O75914 P01111 P01112 P04049 P06241 P07948 P13598 P17612 P19838 P22612 P22694 P32942 Q01201 Q04206 Q09472 Q13153 Q13177 Q92793 Q9NNX6	CBP CD209 CLEC4L CREBBP EP300 FYN HRAS HRAS1 ICAM2 ICAM3 JTK8 LYN MSK1 NFKB1 NFKB3 NRAS OPHN3 P300 PAK1 PAK2 PAK3 PKACA PRKACA PRKACB PRKACG RAF RAF1 RELA RELB RPS6KA5	Homo sapiens (human)
Imatinib-resistant PDGFR mutants	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA	Homo sapiens (human)
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 Neurogenic locus notch homolog protein 1 Protein jagged-1 Protein jagged-2	O00548 O14672 P46531 P78504 P78536 Q9NR61 Q9Y219	ADAM10 ADAM17 CSVP DLL1 DLL4 JAG1 JAG2 JAGL1 KUZ MADM NOTCH1 TACE TAN1	Homo sapiens (human)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	Cytochrome P450 1A1 Cytochrome P450 1A2 Cytochrome P450 1B1 Cytochrome P450 2C19 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2U1 Cytochrome P450 4A11 Cytochrome P450 4F2	P04798 P05177 P10632 P11712 P33261 P78329 Q02928 Q16678 Q7Z449	CYP1A1 CYP1A2 CYP1B1 CYP2C10 CYP2C19 CYP2C8 CYP2C9 CYP2U1 CYP4A11 CYP4A2 CYP4F2	Homo sapiens (human)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Deoxyribose-phosphate aldolase Glucose-6-phosphate 1-dehydrogenase Phosphopentomutase Ribokinase Ribose-5-phosphate isomerase Ribulose-phosphate 3-epimerase-like protein 1 Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase	O95336 P11413 P29401 P37837 P49247 P52209 Q2QD12 Q96AT9 Q96G03 Q9H477 Q9UHJ6 Q9Y315	CARKL DERA G6PD PGD PGDH PGLS PGM2 RBKS RBSK RPE RPEL1 RPI RPIA SHPK TAL TALDO TALDO1 TALDOR TKT	Homo sapiens (human)	G31080DL
Processing of Capped Intron-Containing Pre-mRNA	Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein A3 Heterogeneous nuclear ribonucleoprotein D0 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H2 Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoprotein L Heterogeneous nuclear ribonucleoprotein M Heterogeneous nuclear ribonucleoprotein R Heterogeneous nuclear ribonucleoprotein U Heterogeneous nuclear ribonucleoproteins A2/B1 Heterogeneous nuclear ribonucleoproteins C1/C2 N6-adenosine-methyltransferase catalytic subunit N6-adenosine-methyltransferase non-catalytic subunit Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Poly(rC)-binding protein 1 Poly(rC)-binding protein 2 Polyadenylate-binding protein 2 Polypyrimidine tract-binding protein 1 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-splicing regulator WTAP RNA-binding motif protein, X chromosome RNA-binding protein 10 RNA-binding protein FUS Serine/arginine-rich splicing factor 10 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 12 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 8 Serine/arginine-rich splicing factor 9 Symplekin Transformer-2 protein homolog beta Y-box-binding protein 1 pre-mRNA 3' end processing protein WDR33	O15514 O43390 O43809 O75494 O94913 O95639 P07910 P09651 P13984 P14866 P19387 P19388 P22626 P24928 P26599 P30876 P31943 P33240 P35269 P35637 P36954 P38159 P51003 P51991 P52272 P52298 P52434 P52435 P52597 P53803 P55795 P61218 P61978 P62487 P62875 P62995 P67809 P84103 P98175 Q00839 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q14103 Q15007 Q15365 Q15366 Q16629 Q6UN15 Q86U42 Q86U44 Q8N684 Q8WXF0 Q92797 Q92989 Q9BRL6 Q9C0J8 Q9H0L4 Q9HCE5 Q9P2I0 Q9UKF6	ASF AUF1 C1orf199 CBP20 CBP80 CFIM25 CLP1 CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 DXS8237E FIP1 FIP1L1 FTP3 FUS FUSIP1 FUSIP2 GPATC9 GPATCH9 GTF2F1 GTF2F2 HEAB HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPM HNRNPR HNRNPU HNRPA1 HNRPA2B1 HNRPA3 HNRPC HNRPD HNRPF HNRPG HNRPH HNRPH1 HNRPH2 HNRPK HNRPL HNRPM HNRPR HNRPU HRS KIAA0105 KIAA0122 KIAA0689 KIAA0824 KIAA1367 KIAA1627 METTL14 METTL3 MTA70 NAGR1 NAR NCBP NCBP1 NCBP2 NEB1 NSEP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PCBP1 PCBP2 PCF11 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PTB PTBP1 RAP30 RAP74 RBM10 RBMX RBMXP1 RHE RPB7 SAFA SF2 SF2P33 SFRS1 SFRS10 SFRS11 SFRS13A SFRS13B SFRS19 SFRS2 SFRS2B SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SPK SRP20 SRP30C SRP40 SRP46 SRP55 SRP75 SRRP35 SRSF1 SRSF10 SRSF11 SRSF12 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SRSF9 SYMPK TASR TLS TRA2B U21.1 WDC146 WDR33 WTAP YB1 YBX1	Homo sapiens (human)
Signaling by LTK	ALK and LTK ligand 1 ALK and LTK ligand 2 Activated CDC42 kinase 1 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Leukocyte tyrosine kinase receptor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Son of sevenless homolog 1	O00459 P27986 P29376 P35568 P42336 P42338 P62993 Q07889 Q07912 Q6UX46 Q6UXT8	ACK1 ALKAL1 ALKAL2 ASH FAM150A FAM150B GRB1 GRB2 IRS1 LTK PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 SOS1 TNK2 TYK1	Homo sapiens (human)
Pyrophosphate hydrolysis	Inorganic pyrophosphatase 2, mitochondrial Inorganic pyrophosphatase Phospholysine phosphohistidine inorganic pyrophosphate phosphatase	Q15181 Q9H008 Q9H2U2	IOPPP LHPP PP PPA1 PPA2	Homo sapiens (human)
SUMOylation of transcription factors	Cellular tumor antigen p53 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 E3 ubiquitin-protein ligase Mdm2 Forkhead box protein L2 Hypermethylated in cancer 1 protein Metastasis-associated protein MTA1 Microphthalmia-associated transcription factor SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 TP53-binding protein 1 Transcription factor AP-2 gamma Transcription factor AP-2-beta Transcription factor Sp3 Tumor suppressor ARF	O75030 O75925 P04637 P55854 P58012 P61956 P63165 P63279 Q00987 Q02447 Q12888 Q13330 Q14526 Q8N2W9 Q8N726 Q92481 Q92754 Q9Y6X2	BHLHE32 CDKN2 CDKN2A DDXBP1 FOXL2 HIC1 MDM2 MITF MLM MTA1 P53 PIAS1 PIAS3 PIAS4 PIASG SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SP3 SUMO1 SUMO2 SUMO3 TFAP2B TFAP2C TP53 TP53BP1 UBC9 UBCE9 UBE2I UBL1 ZBTB29	Homo sapiens (human)

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