GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1126 - 1150** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼
RHOF GTPase cycle	A-kinase anchor protein 12 Actin, cytoplasmic 1 Alpha-actinin-1 Ankyrin repeat domain-containing protein SOWAHC BAR/IMD domain-containing adapter protein 2-like 1 BAR/IMD domain-containing adapter protein 2-like 2 Brain acid soluble protein 1 Caveolin-1 Cell surface glycoprotein MUC18 DEP domain-containing protein 1B Extended synaptotagmin-1 F-actin-capping protein subunit beta FERM, ARHGEF and pleckstrin domain-containing protein 1 Gamma-adducin Lamin-B1 Lamina-associated polypeptide 2, isoforms beta/gamma Metalloreductase STEAP3 POTE ankyrin domain family member E Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3-phosphate phosphatase MTMR1 Protein diaphanous homolog 1 Protein diaphanous homolog 2 Protein diaphanous homolog 3 Ras-related protein Rab-7a Rho GTPase-activating protein 12 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 32 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho GTPase-activating protein SYDE1 Rho-related GTP-binding protein RhoF SLIT-ROBO Rho GTPase-activating protein 2 Sentrin-specific protease 1 Sodium bicarbonate cotransporter 3 Soluble lamin-associated protein of 75 kDa Synaptosomal-associated protein 23 Torsin-1A-interacting protein 1 Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3	A7KAX9 O00161 O00459 O60610 O60879 O75044 P12814 P20700 P27986 P42167 P43121 P47756 P51149 P60709 P80723 Q02952 Q03135 Q07960 Q13017 Q13459 Q13613 Q15836 Q53LP3 Q5JTV8 Q5T5U3 Q658P3 Q6S8J3 Q6UXY1 Q6ZW31 Q8IWW6 Q8TAA9 Q8WUY9 Q9BSJ8 Q9C0H5 Q9HBH0 Q9NSV4 Q9P0U3 Q9UEY8 Q9UHR4 Q9Y4F1 Q9Y6M7 Q9Y6X4	A26C1A ACTB ACTN1 ADD3 ADDL AKAP12 AKAP250 ANKRD57 ARHF ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP21 ARHGAP32 ARHGAP34 ARHGAP39 ARHGAP5 BAIAP2L1 BAIAP2L2 BASP1 BT C2orf26 CAPZB CAV CAV1 CDC42GAP CDEP DEPDC1B DIA DIAP1 DIAP3 DIAPH1 DIAPH2 DIAPH3 ESYT1 FAM169A FAM62A FARP1 FNBP2 GRB1 GRIT IRTKS KIAA0456 KIAA0712 KIAA0747 KIAA0888 KIAA1424 KIAA1688 LAP1 LAP2 LMN2 LMNB LMNB1 MBC2 MCAM MTMR1 MUC18 MYO9B MYR5 NAP22 NBC2 NBC2B NBC3 NBCn1 PIK3R1 PIK3R2 PLEKHC2 POTE2 POTEE RAB7 RAB7A RHOF RHOGAP1 RHOGAP5 RICS RIF SBC2 SENP1 SLC4A6 SLC4A7 SNAP23 SOWAHC SRGAP2 SRGAP2A STB2 STEAP3 SYB3 SYDE1 TMPO TOR1AIP1 TSAP6 VAMP3 VANGL1 XTP8	Homo sapiens (human)
PPARA activates gene expression	3'-5' exoribonuclease HELZ2 5-aminolevulinate synthase, non-specific, mitochondrial Acyl-CoA (8-3)-desaturase Angiopoietin-related protein 4 Angiotensinogen Ankyrin repeat domain-containing protein 1 Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Basic helix-loop-helix ARNT-like protein 1 Bile acid receptor CREB-binding protein Carnitine O-palmitoyltransferase 1, liver isoform Carnitine O-palmitoyltransferase 2, mitochondrial Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Constitutive coactivator of peroxisome proliferator-activated receptor gamma Cyclin-C Cyclin-dependent kinase 19 Cyclin-dependent kinase 8 Cytochrome P450 1A1 Cytochrome P450 4A11 Cytochrome P450 7A1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Fatty acid-binding protein, liver Four and a half LIM domains protein 2 G protein pathway suppressor 2 G0/G1 switch protein 2 Glioma pathogenesis-related protein 1 Grainyhead-like protein 1 homolog Histone acetyltransferase p300 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic Hydroxymethylglutaryl-CoA synthase, mitochondrial Long-chain fatty acid transport protein 1 Long-chain-fatty-acid--CoA ligase 1 Mediator of RNA polymerase II transcription subunit 10 Mediator of RNA polymerase II transcription subunit 11 Mediator of RNA polymerase II transcription subunit 12 Mediator of RNA polymerase II transcription subunit 13-like Mediator of RNA polymerase II transcription subunit 13 Mediator of RNA polymerase II transcription subunit 14 Mediator of RNA polymerase II transcription subunit 15 Mediator of RNA polymerase II transcription subunit 16 Mediator of RNA polymerase II transcription subunit 17 Mediator of RNA polymerase II transcription subunit 18 Mediator of RNA polymerase II transcription subunit 19 Mediator of RNA polymerase II transcription subunit 1 Mediator of RNA polymerase II transcription subunit 20 Mediator of RNA polymerase II transcription subunit 21 Mediator of RNA polymerase II transcription subunit 22 Mediator of RNA polymerase II transcription subunit 23 Mediator of RNA polymerase II transcription subunit 24 Mediator of RNA polymerase II transcription subunit 25 Mediator of RNA polymerase II transcription subunit 26 Mediator of RNA polymerase II transcription subunit 27 Mediator of RNA polymerase II transcription subunit 28 Mediator of RNA polymerase II transcription subunit 29 Mediator of RNA polymerase II transcription subunit 30 Mediator of RNA polymerase II transcription subunit 31 Mediator of RNA polymerase II transcription subunit 4 Mediator of RNA polymerase II transcription subunit 6 Mediator of RNA polymerase II transcription subunit 7 Mediator of RNA polymerase II transcription subunit 8 Mediator of RNA polymerase II transcription subunit 9 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Metal regulatory transcription factor 1 NADP-dependent malic enzyme Neuronal PAS domain-containing protein 2 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 3 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Nuclear receptor subfamily 1 group D member 1 Nuclear respiratory factor 1 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Perilipin-2 Peroxisomal membrane protein 11A Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Peroxisome proliferator-activated receptor gamma Phosphatidylcholine translocator ABCB4 Phospholipid-transporting ATPase ABCA1 Platelet glycoprotein 4 Ral guanine nucleotide dissociation stimulator-like 1 Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Rho guanine nucleotide exchange factor TIAM2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Squalene synthase Steroid hormone receptor ERR1 Sterol regulatory element-binding protein 2 Sulfotransferase 2A1 Thioredoxin reductase 1, cytoplasmic Thyroid hormone receptor-associated protein 3 Transcription factor Sp1 Tribbles homolog 3 Trimethylguanosine synthase Tumor necrosis factor receptor superfamily member 21 UDP-glucuronosyltransferase 1A9	A0JLT2 A9YTQ3 O00327 O15379 O15516 O43513 O60244 O60427 O60656 O60907 O75192 O75376 O75448 O75509 O75586 O95402 O95477 P01019 P02647 P02652 P04798 P07148 P08047 P11310 P11474 P13196 P16671 P19793 P20393 P21439 P22680 P23511 P23786 P24863 P25208 P27469 P27540 P28702 P33121 P35398 P35869 P37231 P37268 P48060 P48163 P49336 P50416 P54868 P55055 Q01581 Q02928 Q06520 Q07869 Q09472 Q12772 Q13133 Q13227 Q13503 Q13952 Q14192 Q14686 Q14872 Q15327 Q15528 Q15596 Q15648 Q15788 Q16656 Q16881 Q3L8U1 Q6P2C8 Q6PCB7 Q6Q788 Q6STE5 Q71F56 Q71SY5 Q86X55 Q86YN6 Q8IVF5 Q92793 Q93074 Q96EK7 Q96G25 Q96HR3 Q96RI1 Q96RN5 Q96RS0 Q96RU7 Q99541 Q99743 Q9BTT4 Q9BUE0 Q9BWU1 Q9BY76 Q9BYK8 Q9BZK7 Q9H204 Q9H944 Q9HBZ2 Q9NPJ6 Q9NVC6 Q9NWA0 Q9NX70 Q9NZI5 Q9NZL6 Q9P086 Q9UBK2 Q9UHV7 Q9ULK4 Q9Y2W1 Q9Y2X0 Q9Y3C7 Q9Y618 Q9Y6Q9	ABC1 ABCA1 ABCB4 ACADM ACID1 ACSL1 ACSVL5 ADFP AGT AHR AHRR AIB1 AIB3 ALAS1 ALAS3 ALASH ANGPTL4 ANKRD1 APOA1 APOA2 APOA5 ARC100 ARC105 ARC130 ARC150 ARC205 ARC240 ARC250 ARC33 ARC34 ARC36 ARC70 ARC77 ARC92 ARNT ARNT2 ARNTL ARP4 BAF60C BAR BCLAF2 BHLHD2 BHLHE1 BHLHE2 BHLHE42 BHLHE5 BHLHE74 BHLHE75 BHLHE76 BHLHE77 BHLHE8 BHLHE9 BMAL1 C193 C20orf97 CAGH45 CARM1 CARP CBP CCNC CCPG CD36 CDC2L6 CDK11 CDK19 CDK8 CERP CHD9 CLOCK CPT1 CPT1A CPT2 CREBBP CRSP1 CRSP2 CRSP200 CRSP3 CRSP34 CRSP4 CRSP6 CRSP7 CRSP8 CRSP9 CTG26 CTG7A CXorf4 CYP1A1 CYP4A11 CYP4A2 CYP7 CYP7A1 DR6 DRAL DRIP100 DRIP130 DRIP150 DRIP205 DRIP230 DRIP36 DRIP77 DRIP80 DRIP92 EAR1 EG1 EP300 ERR1 ESRL1 ESRRA EXLM1 FABP1 FABPL FACL1 FACL2 FADS1 FADSD5 FAM120B FATP1 FDFT1 FHL2 FXR G0S2 GLIPR GLIPR1 GNT1 GP3B GP4 GPS2 GRHL1 GRIM12 HA1A2 HAP3 HCA137 HDAC3 HELZ2 HFARP HMGCS HMGCS1 HMGCS2 HOPA HREV HRR1 HST IRA1 IXL KDRF KIAA0130 KIAA0181 KIAA0192 KIAA0307 KIAA0308 KIAA0334 KIAA0593 KIAA0959 KIAA1025 KIAA1028 KIAA1047 KIAA1216 KIAA1234 KIAA1769 KIAA1838 KIAA2016 KISH2 LACS LACS1 LACS2 LBP32 LCMR1 LEM6 LXRA LXRB MDR3 ME1 MED1 MED10 MED11 MED12 MED13 MED13L MED14 MED15 MED16 MED17 MED18 MED19 MED20 MED21 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 MED9 MGR MOP3 MOP4 MTF1 NCOA1 NCOA2 NCOA3 NCOA6 NCOA6IP NCOR1 NCOR2 NER NFYA NFYB NFYC NIPK NPAS2 NR1C1 NR1C3 NR1D1 NR1F1 NR1H2 NR1H3 NR1H4 NR2B1 NR2B2 NR3B1 NRF1 P300 PASD3 PASD4 PBP PCQAP PERC PEX11 PEX11A PGAR PGC1 PGC1A PGC1B PGY3 PIMT PLIN2 PPAR PPARA PPARBP PPARG PPARGBP PPARGC1 PPARGC1A PPARGC1B PRIC285 PRIC320 PRMT4 PROSIT240 PTOV2 RAC3 RAP250 RAP3 RB18A RGL RGL1 RGR1 RIP14 RORA RTVP1 RXRA RXRB RZRA SERPINA8 SKIP3 SLC27A1 SLIM3 SMARCD3 SOH1 SP1 SRB7 SRC1 SRC2 SREBF2 SREBP2 STD STEF SULT2A1 SUR2 SURB7 SURF5 TBL1 TBL1X TBL1XR1 TBLR1 TFCP2L2 TGS1 THRAL THRAP1 THRAP2 THRAP3 THRAP4 THRAP5 THRAP6 TIAM2 TIF2 TIG1 TNFRSF21 TNRC11 TNRC7 TRAM1 TRAP100 TRAP150 TRAP170 TRAP220 TRAP230 TRAP240 TRAP240L TRAP25 TRAP80 TRB3 TRBP TRFP TRIB3 TRIP2 TSFP1 TXNRD1 UGT1 UGT1A9 UNR VDRIP	Homo sapiens (human)
RUNX3 regulates YAP1-mediated transcription	CCN family member 2 Runt-related transcription factor 3 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-4 Transcriptional enhancer factor TEF-5 WW domain-containing transcription regulator protein 1	P28347 P29279 P46937 Q13761 Q15561 Q15562 Q99594 Q9GZV5	AML2 CBFA3 CCN2 CTGF HCS24 IGFBP8 PEBP2A3 RTEF1 RUNX3 TAZ TCF13 TCF13L1 TEAD1 TEAD2 TEAD3 TEAD4 TEAD5 TEF1 TEF3 TEF4 TEF5 WWTR1 YAP1 YAP65	Homo sapiens (human)
Cobalamin (Cbl) metabolism	Cobalamin trafficking protein CblD Corrinoid adenosyltransferase MMAB Cyanocobalamin reductase / alkylcobalamin dealkylase Methionine synthase reductase Methionine synthase Methylmalonic aciduria type A protein, mitochondrial Methylmalonyl-CoA mutase, mitochondrial	P22033 Q8IVH4 Q96EY8 Q99707 Q9H3L0 Q9UBK8 Q9Y4U1	C2orf25 CL25022 MMAA MMAB MMACHC MMADHC MMUT MTR MTRR MUT	Homo sapiens (human)
Removal of the Flap Intermediate from the C-strand	Adrenocortical dysplasia protein homolog Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA replication ATP-dependent helicase/nuclease DNA2 Flap endonuclease 1 Proliferating cell nuclear antigen Protection of telomeres protein 1 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P15927 P27694 P28340 P35244 P39748 P49005 P51530 P54274 Q14191 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD DNA2 DNA2L DRIP5 FEN1 KIAA0039 KIAA0083 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAD2 RAP1 RECQ3 RECQL2 REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 WRN	Homo sapiens (human)
FGFR3c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Polypeptide N-acetylgalactosaminyltransferase 3	O43320 O76093 P05230 P08620 P09038 P31371 Q14435 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB GALNT3 HST HSTF1 HYPF KS3	Homo sapiens (human)
Endosomal Sorting Complex Required For Transport (ESCRT)	Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 5 Charged multivesicular body protein 6 Charged multivesicular body protein 7 Hepatocyte growth factor-regulated tyrosine kinase substrate Multivesicular body subunit 12A Multivesicular body subunit 12B Polyubiquitin-B Polyubiquitin-C Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Tumor susceptibility gene 101 protein Ubiquitin-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein sorting-associated protein 37A Vacuolar protein sorting-associated protein 37B Vacuolar protein sorting-associated protein 37C Vacuolar protein sorting-associated protein 37D Vacuolar protein sorting-associated protein 4A Vacuolar protein sorting-associated protein 4B Vacuolar protein sorting-associated protein VTA1 homolog Vacuolar protein-sorting-associated protein 25 Vacuolar protein-sorting-associated protein 36 Vacuolar-sorting protein SNF8	A5D8V6 O14964 O43633 O75351 O75886 P0CG47 P0CG48 P62979 P62987 Q86VN1 Q86XT2 Q8NEZ2 Q8WUX9 Q92783 Q96CF2 Q96EY5 Q96FZ7 Q96H20 Q99816 Q9BRG1 Q9BY43 Q9H444 Q9H7P6 Q9H9H4 Q9NP79 Q9NZ09 Q9NZZ3 Q9UK41 Q9UN37 Q9UQN3 Q9Y3E7	BC2 C13orf9 C14orf123 C20orf178 C6orf55 C9orf28 C9orf83 CFBP CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CHMP6 CHMP7 DERP9 EAP20 EAP30 EAP45 FAM125A FAM125B HBP HCRP1 HGS HRS MVB12A MVB12B NEDF PML39 RPS27A SHAX1 SHAX2 SHAX3 SKD1 SNF7DC2 SNF8 STAM STAM1 STAM2 TSG101 UBA52 UBA80 UBAP1 UBB UBC UBCEP1 UBCEP2 VPS20 VPS24 VPS25 VPS28 VPS36 VPS37A VPS37B VPS37C VPS37D VPS4 VPS42 VPS4A VPS4B VTA1 WBSCR24	Homo sapiens (human)
RHO GTPases activate CIT	Citron Rho-interacting kinase Cyclin-dependent kinase inhibitor 1B Disks large homolog 4 Kinesin-like protein KIF14 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Protein regulator of cytokinesis 1 Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Serine/threonine-protein phosphatase PP1-beta catalytic subunit Transforming protein RhoA	O14578 O14950 O14974 O43663 O60237 P08134 P24844 P35579 P35580 P35749 P46527 P60660 P61586 P62140 P62745 P63000 P78352 Q15058 Q7Z406	ARH12 ARH6 ARH9 ARHA ARHB ARHC CDKN1B CIT CRIK DLG4 KIAA0042 KIAA0866 KIAA0949 KIAA2034 KIF14 KIP1 MBS MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYPT1 MYPT2 MYRL2 PPP1CB PPP1R12A PPP1R12B PRC1 PSD95 RAC1 RHO12 RHOA RHOB RHOC STK21 TC25 p27	Homo sapiens (human)
Virion Assembly and Release	Envelope small membrane protein Membrane protein Nucleoprotein ORF3a protein ORF7a protein Spike glycoprotein	P59594 P59595 P59596 P59632 P59635 P59637	3a 7a E M N S sM	Homo sapiens (human)
RNA Polymerase III Transcription Initiation From Type 3 Promoter	DNA-directed RNA polymerase III subunit RPC10 DNA-directed RNA polymerase III subunit RPC1 DNA-directed RNA polymerase III subunit RPC2 DNA-directed RNA polymerase III subunit RPC3 DNA-directed RNA polymerase III subunit RPC4 DNA-directed RNA polymerase III subunit RPC5 DNA-directed RNA polymerase III subunit RPC6 DNA-directed RNA polymerase III subunit RPC7-like DNA-directed RNA polymerase III subunit RPC7 DNA-directed RNA polymerase III subunit RPC8 DNA-directed RNA polymerase III subunit RPC9 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 POU domain, class 2, transcription factor 1 Protein POLR1D, isoform 2 TATA-box-binding protein Transcription factor IIIB 50 kDa subunit Transcription factor TFIIIB component B'' homolog Zinc finger protein 143 snRNA-activating protein complex subunit 1 snRNA-activating protein complex subunit 2 snRNA-activating protein complex subunit 3 snRNA-activating protein complex subunit 4 snRNA-activating protein complex subunit 5	A6H8Y1 O14802 O15160 O15318 O75575 O75971 P05423 P0DPB5 P14859 P19388 P20226 P52434 P52747 P53803 P61218 P62875 Q13487 Q16533 Q5SXM2 Q92966 Q9BT43 Q9BUI4 Q9H1D9 Q9HAW0 Q9NVU0 Q9NW08 Q9Y2Y1 Q9Y535	BDP1 BN51 BN51T BRF2 BRFU CRCP GTF2D1 KIAA1241 KIAA1452 KIAA1665 KIAA1689 OCT1 OTF1 POLR1C POLR1D POLR1E POLR2E POLR2F POLR2H POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3E POLR3F POLR3G POLR3GL POLR3H POLR3K POLRF POU2F1 RPC11 RPC8 SBF SNAP19 SNAP190 SNAP43 SNAP45 SNAP50 SNAPC1 SNAPC2 SNAPC3 SNAPC4 SNAPC5 STAF TBP TF2D TFIID TFNR ZNF143	Homo sapiens (human)
Constitutive Signaling by AKT1 E17K in Cancer	3-phosphoinositide-dependent protein kinase 1 Bcl2-associated agonist of cell death Caspase-9 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B E3 ubiquitin-protein ligase Mdm2 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Inhibitor of nuclear factor kappa-B kinase subunit alpha Nuclear receptor subfamily 4immunitygroup A member 1 Proline-rich AKT1 substrate 1 Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ribosomal protein S6 kinase beta-2 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tuberin	A8MYZ6 O15111 O15530 O43524 P22736 P31749 P31751 P38936 P42345 P46527 P49815 P49840 P49841 P55211 P85299 P98177 Q00987 Q12778 Q6R327 Q92934 Q96B36 Q9BPZ7 Q9BVC4 Q9UBS0 Q9Y243	AFX AFX1 AKT1 AKT1S1 AKT2 AKT3 BAD BBC6 BCL2L8 CAP20 CASP9 CDKN1 CDKN1A CDKN1B CHUK CIP1 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 FRAP FRAP1 FRAP2 GBL GFRP1 GSK3A GSK3B HMR IKKA KIAA1999 KIP1 LST8 MAPKAP1 MCH6 MDA6 MDM2 MIP1 MLLT7 MLST8 MTOR NAK1 NR4A1 PDK1 PDPK1 PIC1 PKB PKBG PRAS40 PROTOR1 PRR5 RAC RAFT1 RAPT1 RICTOR RPS6KB2 SDI1 SIN1 STK14B TCF16 TSC2 TSC4 WAF1 p27	Homo sapiens (human)
Vitamin B2 (riboflavin) metabolism	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 FAD synthase Riboflavin kinase Solute carrier family 52, riboflavin transporter, member 1 Solute carrier family 52, riboflavin transporter, member 2 Solute carrier family 52, riboflavin transporter, member 3 Tartrate-resistant acid phosphatase type 5	P13686 P22413 Q8NFF5 Q969G6 Q9HAB3 Q9NQ40 Q9NWF4	ACP5 C20orf54 ENPP1 FLAD1 GPR172A GPR172B M6S1 NPPS PAR1 PAR2 PC1 PDNP1 RFK RFT1 RFT2 RFT3 RFVT3 SLC52A1 SLC52A2 SLC52A3	Homo sapiens (human)
Regulation of KIT signaling	E3 ubiquitin-protein ligase CBL Mast/stem cell growth factor receptor Kit Protein kinase C alpha type SH2B adapter protein 2 SH2B adapter protein 3 Son of sevenless homolog 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 6 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 6	O14492 O14544 O15524 P06239 P06241 P07947 P07948 P10721 P17252 P22681 P29350 Q07889 Q9UQQ2	APS CBL CBL2 CIS4 FYN HCP JTK8 KIT LCK LNK LYN PKCA PRKACA PRKCA PTP1C PTPN6 RNF55 SCFR SH2B2 SH2B3 SOCS1 SOCS4 SOCS6 SOS1 SSI1 TIP3 YES YES1	Homo sapiens (human)
Nephron development	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe Delta-like protein 1 Hepatocyte nuclear factor 1-beta Hepatocyte nuclear factor 4-alpha Iroquois-class homeodomain protein IRX-1 Iroquois-class homeodomain protein IRX-2 LIM/homeobox protein Lhx1 POU domain, class 3, transcription factor 3 Protein Wnt-4 Protein Wnt-9b Protein jagged-1 Wilms tumor protein	O00548 O14905 P19544 P20264 P35680 P41235 P48742 P56705 P78414 P78504 Q8NES3 Q9BZI1	BRN1 DLL1 HNF1B HNF4 HNF4A IRX1 IRX2 IRXA1 IRXA2 JAG1 JAGL1 LFNG LHX1 LIM-1 LIM1 NR2A1 OTF8 POU3F3 TCF14 TCF2 WNT14B WNT15 WNT4 WNT9B WT1	Homo sapiens (human)
Platelet homeostasis	P2X purinoceptor 1 P2X purinoceptor 2 P2X purinoceptor 3 P2X purinoceptor 4 P2X purinoceptor 5 P2X purinoceptor 6 P2X purinoceptor 7 Platelet-activating factor acetylhydrolase 2, cytoplasmic	O15547 P51575 P56373 Q93086 Q99487 Q99571 Q99572 Q9UBL9	P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 P2RXL1 P2X1 P2X2 P2X5 P2X5FL P2X6 PAFAH2	Homo sapiens (human)
Transport of the SLBP independent Mature mRNA	Aladin E3 SUMO-protein ligase RanBP2 Eukaryotic translation initiation factor 4E Nuclear RNA export factor 1 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog THO complex subunit 4 mRNA export factor RAE1	A8CG34 O15504 O75694 P06730 P12270 P35658 P37198 P49790 P49792 P52298 P55735 P57740 P78406 Q09161 Q12769 Q5SRE5 Q7Z3B4 Q86V81 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UBU9 Q9UKX7	AAAS ADRACALA ALY ALYREF BEF C7orf14 CAIN CAN CBP20 CBP80 CG1 D3S1231E EIF4E EIF4EL1 EIF4F KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MP44 MRNP41 NCBP NCBP1 NCBP2 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 NXF1 PCNT1 POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R TAP THOC4 TMEM48 TPR	Homo sapiens (human)
Androgen biosynthesis	17-beta-hydroxysteroid dehydrogenase type 3 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Glycoprotein hormones alpha chain Lutropin subunit beta Polyprenal reductase Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Very-long-chain 3-oxoacyl-CoA reductase	P01189 P01215 P01229 P05093 P14060 P18405 P26439 P31213 P37058 Q53GQ0 Q9H8P0	3BH CGA CYP17 CYP17A1 EDH17B3 HSD17B12 HSD17B3 HSD3B1 HSD3B2 HSDB3A HSDB3B LHB POMC S17AH SDR12C1 SDR12C2 SRD5A1 SRD5A2 SRD5A2L SRD5A3	Homo sapiens (human)
RA biosynthesis pathway	2-aminomuconic semialdehyde dehydrogenase Alcohol dehydrogenase 1A Alcohol dehydrogenase 1C Aldehyde dehydrogenase 1A1 Aldo-keto reductase family 1 member C3 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Cellular retinoic acid-binding protein 1 Cytochrome P450 26A1 Cytochrome P450 26B1 Cytochrome P450 26C1 Dehydrogenase/reductase SDR family member 4 Dehydrogenase/reductase SDR family member 9 Epidermal retinol dehydrogenase 2 Retinal dehydrogenase 2 Retinaldehyde dehydrogenase 3 Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 13 Retinol dehydrogenase 14 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Short-chain dehydrogenase/reductase 3	O43174 O75452 O75911 O94788 P00326 P00352 P07327 P08319 P29762 P42330 P47895 Q6V0L0 Q8IZV5 Q8N3Y7 Q8NBN7 Q8TC12 Q92781 Q9BPW9 Q9BTZ2 Q9H2A2 Q9HBH5 Q9NR63	ADH1 ADH1A ADH1C ADH2 ADH3 ADH4 AKR1C3 ALDC ALDH1 ALDH12 ALDH1A1 ALDH1A2 ALDH1A3 ALDH6 ALDH8A1 ARSDR1 CRABP1 CYP26 CYP26A1 CYP26A2 CYP26B1 CYP26C1 DDH1 DHRS3 DHRS4 DHRS9 HSD17B5 HSD17B9 KIAA0119 P450RAI1 P450RAI2 PAN2 PGFS PSDR1 PUMB1 RALDH2 RBP5 RDH1 RDH10 RDH11 RDH13 RDH14 RDH15 RDH16 RDH17 RDH5 RDHE2 RODH4 SDR16C1 SDR16C4 SDR16C5 SDR25C2 SDR7C1 SDR7C3 SDR7C4 SDR9C4 SDR9C5 SDR9C8	Homo sapiens (human)
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway	DNA polymerase beta DNA repair nuclease/redox regulator APEX1	P06746 P27695	APE APE1 APEX APEX1 APX HAP1 POLB REF1	Homo sapiens (human)
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	Antiviral innate immune response receptor RIG-I Caspase-10 Caspase-8 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 FAS-associated death domain protein Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator Receptor-interacting serine/threonine-protein kinase 1	O14920 O15111 O95786 Q13158 Q13546 Q14258 Q14790 Q7Z434 Q8IUD6 Q92851 Q9BYX4 Q9C037 Q9Y6K9	CASP10 CASP8 CHUK DDX58 EFP FADD FIP3 IFIH1 IKBKB IKBKG IKKA IKKB IPS1 KIAA1271 MAVS MCH4 MCH5 MDA5 MORT1 NEMO RH116 RIGI RIP RIP1 RIPK1 RNF135 RNF147 RNF87 TCF16 TRIM25 TRIM4 VISA ZNF147	Homo sapiens (human)
ARL13B-mediated ciliary trafficking of INPP5E	ADP-ribosylation factor-like protein 13B Phosphatidylinositol polyphosphate 5-phosphatase type IV Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	O43924 Q3SXY8 Q9NRR6	ARL13B ARL2L1 INPP5E PDE6D PDED	Homo sapiens (human)
Intestinal infectious diseases	Guanylyl cyclase C Heat-stable enterotoxin ST-IA/ST-P Na(+)/H(+) exchange regulatory cofactor NHE-RF4	P01559 P25092 Q86UT5	GUC2C GUCY2C IKEPP NHERF4 PDZD3 PDZK2 STAR sta1	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain-containing protein 2 Choriogonadotropin subunit beta 3 Epidermal growth factor receptor Estrogen receptor Glycoprotein hormones alpha chain Mast/stem cell growth factor receptor Kit Protransforming growth factor alpha Receptor tyrosine-protein kinase erbB-2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcriptional repressor protein YY1 Vascular endothelial growth factor A, long form	P00533 P01135 P01215 P03372 P04626 P05549 P0DN86 P10721 P15692 P25490 Q6PL18 Q92481 Q92754	AP2TF ATAD2 CGA CGB CGB3 CGB5 CGB8 EGFR ERBB ERBB1 ERBB2 ESR ESR1 HER1 HER2 INO80S KIT MLN19 NEU NGL NR3A1 SCFR TFAP2 TFAP2A TFAP2B TFAP2C TGFA VEGF VEGFA YY1	Homo sapiens (human)
Signaling by RAS GAP mutants	GTPase HRas GTPase KRas GTPase NRas	P01111 P01112 P01116	HRAS HRAS1 KRAS KRAS2 NRAS RASK2	Homo sapiens (human)
Formation of the cornified envelope	Calpain small subunit 1 Calpain-1 catalytic subunit Caspase-14 Chymotrypsin-like elastase family member 2A Corneodesmosin Cornifin-A Cornifin-B Cystatin-A Desmocollin-1 Desmocollin-2 Desmocollin-3 Desmoglein-1 Desmoglein-2 Desmoglein-3 Desmoglein-4 Desmoplakin Elafin Envoplakin Filaggrin Furin Involucrin Junction plakoglobin Kallikrein-12 Kallikrein-13 Kallikrein-14 Kallikrein-5 Kallikrein-8 Kazrin Late cornified envelope protein 1A Late cornified envelope protein 1B Late cornified envelope protein 1C Late cornified envelope protein 1D Late cornified envelope protein 1E Late cornified envelope protein 1F Late cornified envelope protein 2A Late cornified envelope protein 2B Late cornified envelope protein 2C Late cornified envelope protein 2D Late cornified envelope protein 3A Late cornified envelope protein 3B Late cornified envelope protein 3C Late cornified envelope protein 3D Late cornified envelope protein 3E Late cornified envelope protein 4A Late cornified envelope protein 5A Late cornified envelope protein 6A Late cornified envelope-like proline-rich protein 1 Lipase member J Lipase member K Lipase member M Lipase member N Loricrin Periplakin Plakophilin-1 Plakophilin-2 Plakophilin-3 Plakophilin-4 Proprotein convertase subtilisin/kexin type 6 Prostasin Protein-glutamine gamma-glutamyltransferase 5 Protein-glutamine gamma-glutamyltransferase K Repetin Serine protease inhibitor Kazal-type 5 Serine protease inhibitor Kazal-type 6 Serine protease inhibitor Kazal-type 9 Small proline-rich protein 2A Small proline-rich protein 2B Small proline-rich protein 2D Small proline-rich protein 2E Small proline-rich protein 2F Small proline-rich protein 2G Small proline-rich protein 3 Suppressor of tumorigenicity 14 protein Trichohyalin p53 apoptosis effector related to PMP-22	A0A183 O14633 O43548 O60259 O60437 P01040 P04632 P07384 P07476 P08217 P09958 P14923 P15924 P19957 P20930 P22528 P22531 P22532 P22735 P23490 P29122 P31944 P32926 P35321 P35325 P35326 Q02413 Q02487 Q07283 Q08554 Q13835 Q14126 Q14574 Q15517 Q16651 Q5DT21 Q5T5A8 Q5T5B0 Q5T751 Q5T752 Q5T753 Q5T754 Q5T7P2 Q5T7P3 Q5T871 Q5TA76 Q5TA77 Q5TA78 Q5TA79 Q5TA81 Q5TA82 Q5TCM9 Q5VXI9 Q5VXJ0 Q5VYY2 Q5W064 Q674X7 Q6UWN8 Q6XPR3 Q86SJ6 Q92817 Q96FX8 Q96RM1 Q99569 Q99959 Q9BYE3 Q9BYE4 Q9NQ38 Q9P0G3 Q9UBC9 Q9UKR0 Q9UKR3 Q9Y337 Q9Y446 Q9Y5Y6	C1orf196 C1orf44 CANPL1 CAPN1 CAPN4 CAPNS CAPNS1 CASP14 CDHF1 CDHF13 CDHF2 CDHF3 CDHF4 CDHF5 CDHF6 CDSN CELA2A CSTA CTNNG DP3 DSC1 DSC2 DSC3 DSC4 DSG1 DSG2 DSG3 DSG4 DSP ELA2A EVPL FLG FUR FURIN IVL JUP KAZ KAZN KCP1 KIAA0568 KIAA1026 KLK12 KLK13 KLK14 KLK5 KLK8 KLKL4 KLKL5 KLKL6 KRTCAP1 KTG LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LCE6A LEKTI2 LELP1 LEP1 LEP10 LEP11 LEP12 LEP13 LEP14 LEP15 LEP16 LEP17 LEP18 LEP2 LEP3 LEP4 LEP5 LEP6 LEP8 LEP9 LIPJ LIPK LIPL1 LIPL2 LIPL3 LIPL4 LIPM LIPN LOR LORICRIN LRN NRPN PACE PACE4 PCSK3 PCSK6 PERP PI3 PIGPC1 PKP1 PKP2 PKP3 PKP4 PPL PRSS14 PRSS19 PRSS8 RPTN SCTE SNC19 SPINK5 SPINK6 SPINK9 SPRC SPRL1A SPRL1B SPRL2A SPRL3A SPRL4A SPRL5A SPRL6A SPRL6B SPRR1A SPRR1B SPRR2A SPRR2B SPRR2D SPRR2E SPRR2F SPRR2G SPRR3 ST14 STF1 STFA TADG14 TADG15 TCHH TGM1 TGM5 TGMX THH THL THW TRHY WAP3 WFDC14 XP5	Homo sapiens (human)

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