GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1451 - 1475** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Signaling by FGFR3 fusions in cancer	Fibroblast growth factor receptor 3	P22607	FGFR3 JTK4	Homo sapiens (human)
Cell surface interactions at the vascular wall	Apolipoprotein B-100 CD177 antigen CD44 antigen CD48 antigen CD99 antigen-like protein 2 CD99 antigen Carcinoembryonic antigen-related cell adhesion molecule 1 Carcinoembryonic antigen-related cell adhesion molecule 3 Carcinoembryonic antigen-related cell adhesion molecule 5 Carcinoembryonic antigen-related cell adhesion molecule 6 Carcinoembryonic antigen-related cell adhesion molecule 8 Coxsackievirus and adenovirus receptor E-selectin Endothelial cell-selective adhesion molecule Endothelial protein C receptor Epithelial cell adhesion molecule Erythrocyte binding antigen-140 Erythrocyte-binding antigen 175 Fibronectin Glycophorin-A Glycophorin-B Glycophorin-C Glypican-1 Golgi apparatus protein 1 Growth arrest-specific protein 6 HLA class II histocompatibility antigen gamma chain High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor High affinity immunoglobulin epsilon receptor subunit gamma IGHV7-81 protein Immunoglobulin J chain Immunoglobulin heavy constant alpha 1 Immunoglobulin heavy constant alpha 2 Immunoglobulin heavy constant mu Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin iota chain Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunoglobulin lambda-like polypeptide 1 Immunolglobulin kappa light chain variable region L22 (Fragment) Integrin alpha-4 Integrin alpha-5 Integrin alpha-L Integrin alpha-M Integrin alpha-X Integrin beta-1 Integrin beta-2 Junctional adhesion molecule A Junctional adhesion molecule B Junctional adhesion molecule C Junctional adhesion molecule-like L-selectin Leukocyte surface antigen CD47 Leukosialin Lymphocyte function-associated antigen 3 Macrophage migration inhibitory factor Natural killer cell receptor 2B4 Opacity protein V28 (Fragment) Opacity protein opA50 (Fragment) Opacity protein opA51 (Fragment) Opacity protein opA52 (Fragment) Opacity protein opA53 (Fragment) Opacity protein opA54 Opacity protein opA55 (Fragment) Opacity protein opA56 (Fragment) Opacity protein opA57 (Fragment) Opacity protein opA58 Opacity protein opA59 (Fragment) Opacity protein opA60 (Fragment) Opacity protein opA65 (Fragment) Opacity protein opA66 (Fragment) Opacity protein opA67 (Fragment) Opacity protein opA68 (Fragment) Outer membrane protein P.IIC Oxidized low-density lipoprotein receptor 1 P-selectin glycoprotein ligand 1 P-selectin PRKCA-binding protein Platelet endothelial cell adhesion molecule Platelet factor 4 variant Platelet factor 4 Platelet glycoprotein VI Pre-B lymphocyte protein 3 Pregnancy-specific beta-1-glycoprotein 11 Pregnancy-specific beta-1-glycoprotein 1 Pregnancy-specific beta-1-glycoprotein 2 Pregnancy-specific beta-1-glycoprotein 3 Pregnancy-specific beta-1-glycoprotein 4 Pregnancy-specific beta-1-glycoprotein 5 Pregnancy-specific beta-1-glycoprotein 6 Pregnancy-specific beta-1-glycoprotein 7 Pregnancy-specific beta-1-glycoprotein 8 Pregnancy-specific beta-1-glycoprotein 9 Prothrombin Putative erythrocyte binding protein EBL-1 (Fragment) SLAM family member 5 Signal-regulatory protein gamma Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 T-cell surface antigen CD2 Tetraspanin-7 Thrombomodulin Transforming growth factor beta-1 proprotein Triggering receptor expressed on myeloid cells 1 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10D Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Mer Tyrosine-protein phosphatase non-receptor type substrate 1 UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O00220 O14763 O75056 P00734 P01137 P01591 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01871 P01876 P01877 P02724 P02751 P02776 P04070 P04114 P04211 P04233 P04430 P04432 P04433 P04921 P05107 P05556 P06028 P06241 P06310 P06312 P06315 P06331 P06729 P06731 P07204 P07225 P07948 P08648 P09326 P09888 P0CF74 P0CG04 P0DOY2 P0DOY3 P10720 P11215 P11296 P11297 P11464 P11465 P12018 P13612 P13688 P14151 P14174 P14209 P15814 P16070 P16109 P16150 P16284 P16422 P16581 P18827 P19214 P19256 P20701 P20702 P23083 P30273 P31431 P31997 P34741 P35052 P40198 P40199 P41732 P57087 P78310 P78324 P78380 P80748 Q00887 Q00888 Q00889 Q04874 Q04875 Q04876 Q04877 Q04878 Q04879 Q04880 Q04881 Q04882 Q04883 Q04884 Q04885 Q05033 Q05034 Q08722 Q12866 Q13046 Q14242 Q14393 Q15238 Q16557 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q76NM5 Q86YT9 Q8N6Q3 Q8TCZ2 Q8WWV6 Q92896 Q96AP7 Q9BX67 Q9BZW8 Q9HCN6 Q9NP99 Q9NRD5 Q9P1W8 Q9U4X0 Q9UBN6 Q9UIB8 Q9UKI3 Q9UNN8 Q9UQ72 Q9UQ74 Q9Y624	2B4 A15 AMICA1 APO2 APOB AXLLG B1G1 BCM1 BGP BGP1 BIT BLAST1 C21orf43 CAR CD11A CD11B CD11C CD177 CD18 CD2 CD244 CD43 CD44 CD47 CD48 CD49D CD58 CD66D CD74 CD84 CD99 CD99L2 CEA CEACAM1 CEACAM3 CEACAM5 CEACAM6 CEACAM8 CFR1 CGM1 CGM3 CGM4 CGM6 CLEC8A CR3A CXADR CXCL4 CXCL4V1 DCR2 DHLAG DR4 DR5 DXS1692E ELAM1 EPCAM EPCR ESAM ESL1 F11R F2 FCAMR FCER1G FN FN1 FNRA FNRB FYN GA733-2 GAS6 GLG1 GLIF GLPC GMRP GP6 GPA GPB GPC GPC1 GRMP GYPA GYPB GYPC HSPG1 IGCJ IGHA1 IGHA2 IGHM IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGJ IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGL1 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLL1 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 ITGA4 ITGA5 ITGAL ITGAM ITGAX ITGB1 ITGB2 JAM1 JAM2 JAM3 JAML JCAM JCHAIN JTK8 KIAA0468 KILLER LFA3 LHR LNHR LOX1 LYAM1 LYN M1S2 M4S1 MDF2 MDU2 MDU3 MER MER6 MERTK MFI7 MFR MG160 MIC18 MIC2 MIC2L1 MIC2X MIC2Y MIC4 MIF MMIF MSK12 MXS1 MYD1 NB1 NCA OLR1 PECAM1 PF3D7_1301600 PF4 PF4V1 PICK1 PRKCABP PROC PROCR PROS PROS1 PRV1 PSBG1 PSBG2 PSG1 PSG10 PSG11 PSG12 PSG13 PSG14 PSG2 PSG3 PSG4 PSG5 PSG6 PSG7 PSG8 PSG9 PSGGA PSGGB PTPNS1 SCYB4 SCYB4V1 SDC SDC1 SDC2 SDC3 SDC4 SELE SELL SELP SELPLG SHPS1 SIRP SIRPA SIRPB2 SIRPG SLAMF5 SPN SRBC TACSTD1 TGFB TGFB1 THBD THRM TM4SF2 TNFRSF10A TNFRSF10B TNFRSF10D TRAILR1 TRAILR2 TRAILR4 TREM1 TRICK2 TROP1 TRUNDD TSPAN7 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VEJAM VPREB VPREB1 VPREB3 ZTNFR9 ebl-1 opaA opaB opaC opaD opaE opaF opaG opaH opaI opaJ opaK piiC	Homo sapiens (human)
Negative regulation of FGFR2 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15520 O43320 O76093 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P11487 P21781 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
TICAM1,TRAF6-dependent induction of TAK1 complex	Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 6 Toll-like receptor 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15455 O43318 P0CG47 P0CG48 P62979 P62987 Q15750 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3	KIAA0733 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TLR3 TRAF6 TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Activation of Na-permeable kainate receptors	Glutamate receptor ionotropic, kainate 1 Glutamate receptor ionotropic, kainate 2	P39086 Q13002	GLUR5 GLUR6 GRIK1 GRIK2	Homo sapiens (human)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 GTPase HRas GTPase NRas Son of sevenless homolog 1	O15520 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P31371 Q07889 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 NRAS SOS1	Homo sapiens (human)
Recycling of bile acids and salts	ATP-binding cassette sub-family C member 3 Albumin Bile acid receptor Bile acid-CoA Bile salt export pump Gastrotropin Hepatic sodium/bile acid cotransporter Ileal sodium/bile acid cotransporter Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Organic solute transporter subunit alpha Organic solute transporter subunit beta Retinoic acid receptor RXR-alpha Solute carrier organic anion transporter family member 1A2 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 StAR-related lipid transfer protein 5	O15438 O95342 P02768 P19793 P46721 P51161 Q12908 Q14032 Q14973 Q15596 Q15788 Q86UW1 Q86UW2 Q96RI1 Q9NPD5 Q9NSY2 Q9Y2P5 Q9Y6L6	ABCB11 ABCC3 ACSB ACSVL6 ALB ASBT BAAT BAR BHLHE74 BHLHE75 BSEP CMOAT2 FABP6 FACVL3 FATP5 FXR HRR1 ILBP ILLBP ISBT LST1 LST2 MLP2 MRP3 NCOA1 NCOA2 NR1H4 NR2B1 NTCP NTCP2 OATP OATP1 OATP1A2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC OSTA OSTB RIP14 RXRA SLC10A1 SLC10A2 SLC21A3 SLC21A6 SLC21A8 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B1 SLCO1B3 SRC1 SRC2 STARD5 TIF2	Homo sapiens (human)
Nuclear Envelope Breakdown	Barrier-to-autointegration factor Emerin Inner nuclear membrane protein Man1 LEM domain-containing protein 2 Serine/threonine-protein kinase VRK1	O75531 P50402 Q8NC56 Q99986 Q9Y2U8	BAF BANF1 BCRG1 EDMD EMD LEMD2 LEMD3 MAN1 STA VRK1	Homo sapiens (human)
Cross-presentation of soluble exogenous antigens (endosomes)	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 C-type lectin domain family 4 member K C-type mannose receptor 2 High affinity immunoglobulin gamma Fc receptor I Macrophage mannose receptor 1 Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Putative high affinity immunoglobulin gamma Fc receptor IB	O00231 O00232 O00487 O14818 O43242 P12314 P17980 P20618 P22897 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 Q13200 Q15008 Q16186 Q92637 Q99436 Q99460 Q9UBG0 Q9UJ71 Q9UNM6	ADRM1 C7orf76 CD207 CLEC13D CLEC13DL CLEC13E CLEC4K DSS1 ENDO180 FCG1 FCGR1 FCGR1A FCGR1B FCGR1BP GP110 HC2 HC3 HC8 HC9 HSPC IGFR1 IGFRB KIAA0107 KIAA0709 LMPX LMPY MB1 MIP224 MOV34L MRC1 MRC1L1 MRC2 MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UPARAP X Y Z	Homo sapiens (human)
NFE2L2 regulating anti-oxidant/detoxification enzymes	CREB-binding protein Cyclic AMP-dependent transcription factor ATF-4 Cystine/glutamate transporter Extracellular superoxide dismutase [Cu-Zn] Glutamate--cysteine ligase catalytic subunit Glutamate--cysteine ligase regulatory subunit Glutathione S-transferase A1 Glutathione S-transferase A3 Heme oxygenase 1 Histone acetyltransferase p300 NAD(P)H dehydrogenase [quinone] 1 Nuclear factor erythroid 2-related factor 2 Peroxiredoxin-1 Sulfiredoxin-1 Thioredoxin reductase 1, cytoplasmic Thioredoxin Transcription factor MafK Transcription regulator protein BACH1	O14867 O60675 P08263 P08294 P09601 P10599 P15559 P18848 P48506 P48507 Q06830 Q09472 Q16236 Q16772 Q16881 Q92793 Q9BYN0 Q9UPY5	ATF4 BACH1 C20orf139 CBP CREB2 CREBBP DIA4 EP300 GCLC GCLM GLCL GLCLC GLCLR GRIM12 GSTA1 GSTA3 HMOX1 HO HO1 KDRF MAFK NFE2L2 NMOR1 NQO1 NRF2 P300 PAGA PAGB PRDX1 SLC7A11 SOD3 SRX SRX1 SRXN1 TDPX2 TRDX TRX TRX1 TXN TXNRD1 TXREB	Homo sapiens (human)
Asymmetric localization of PCP proteins	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Frizzled-1 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-7 Frizzled-8 Partitioning defective 6 homolog alpha Polyubiquitin-B Polyubiquitin-C Prickle-like protein 1 Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein Wnt-5a Protein scribble homolog Segment polarity protein dishevelled homolog DVL-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vang-like protein 2	O00231 O00232 O00487 O14641 O14818 O43242 O75084 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P41221 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q13200 Q13467 Q14160 Q14332 Q15008 Q16186 Q96MT3 Q99436 Q99460 Q9H461 Q9HAU4 Q9HCE7 Q9NPB6 Q9NPG1 Q9ULK5 Q9ULV1 Q9UNM6 Q9UP38	ADRM1 C2orf31 C7orf76 CRIB1 DSS1 DVL2 FZD1 FZD2 FZD3 FZD4 FZD5 FZD7 FZD8 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 KIAA0147 KIAA1215 KIAA1625 LAP4 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PAR6A PARD6A PFAAP4 POH1 PRICKLE1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RILP RPS27A SCRB1 SCRIB SEM1 SHFDG1 SHFM1 SMURF1 SMURF2 STB1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VANGL2 VARTUL WNT5A X Y Z	Homo sapiens (human)
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E1 Adhesion G protein-coupled receptor E2 Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Complement decay-accelerating factor Corticoliberin Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor-binding protein Desert hedgehog protein Frizzled-10 Frizzled-1 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-7 Frizzled-8 Frizzled-9 Indian hedgehog protein Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Protein Wnt-10a Protein Wnt-10b Protein Wnt-11 Protein Wnt-16 Protein Wnt-2 Protein Wnt-2b Protein Wnt-3a Protein Wnt-4 Protein Wnt-5a Protein Wnt-6 Protein Wnt-7a Protein Wnt-7b Protein Wnt-8a Protein Wnt-8b Protein Wnt-9a Protein Wnt-9b Protein patched homolog 1 Protein patched homolog 2 Protein smoothened Proto-oncogene Wnt-1 Proto-oncogene Wnt-3 Sonic hedgehog protein Tuberoinfundibular peptide of 39 residues Urocortin-2 Urocortin-3 Urocortin	O00144 O00744 O00755 O14904 O14905 O43323 O60353 O75084 O96014 P01270 P04628 P06850 P08174 P09544 P12272 P24387 P34998 P41221 P48960 P49190 P55089 P56703 P56704 P56705 P56706 Q03431 Q13467 Q13635 Q14246 Q14332 Q14623 Q15465 Q93097 Q93098 Q969E3 Q96A98 Q96RP3 Q99835 Q9BY15 Q9GZT5 Q9H1J5 Q9H461 Q9NPG1 Q9UBV4 Q9UHX3 Q9ULV1 Q9ULW2 Q9UP38 Q9Y6C5 Q9Y6F9	ADGRE1 ADGRE2 ADGRE3 ADGRE5 C2orf31 CD55 CD97 CR CRFBP CRFR CRFR1 CRH CRHBP CRHR CRHR1 DAF DHH EMR1 EMR2 EMR3 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 IHH INT1 INT1L1 INT4 IRP PTCH PTCH1 PTCH2 PTH PTH1R PTH2 PTH2R PTHLH PTHR PTHR1 PTHR2 PTHRP SHH SMO SMOH SPC SRP TIP39 TIPF39 TM7LN3 UCN UCN2 UCN3 URP WNT1 WNT10A WNT10B WNT11 WNT12 WNT13 WNT14 WNT14B WNT15 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT6 WNT7A WNT7B WNT8A WNT8B WNT8D WNT9A WNT9B	Homo sapiens (human)
PI-3K cascade:FGFR3	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	O43320 O76093 P05230 P08620 P09038 P27986 P31371 P42336 Q06124 Q13480 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FRS2 GAB1 GRB1 HST HSTF1 HYPF KS3 PIK3CA PIK3R1 PTP2C PTPN11 SHPTP2	Homo sapiens (human)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9	O43320 O76093 P05230 P08620 P09038 P19174 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB HST HSTF1 HYPF KS3 PLC1 PLCG1	Homo sapiens (human)
Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2)	Solute carrier organic anion transporter family member 2A1	Q92959	OATP2A1 SLC21A2 SLCO2A1	Homo sapiens (human)
Synthesis of PG	5'-3' exonuclease PLD3 5'-3' exonuclease PLD4 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Mitochondrial cardiolipin hydrolase Phosphatidate cytidylyltransferase 2 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 Phospholipase D1 Phospholipase D2	O14939 O95674 Q13393 Q32NB8 Q8IV08 Q8N2A8 Q8WUK0 Q96BZ4	C14orf175 CDS2 MOSP PGS1 PLD1 PLD2 PLD3 PLD4 PLD6 PLIP PTPMT1	Homo sapiens (human)
G beta:gamma signalling through PI3Kgamma	3-phosphoinositide-dependent protein kinase 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide 3-kinase regulatory subunit 6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transforming protein RhoA	O14610 O14775 O15530 O60262 P16520 P31749 P31751 P48736 P50150 P50151 P59768 P61586 P61952 P62873 P62879 P63211 P63215 P63218 Q5UE93 Q8WYR1 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9Y243	AKT1 AKT2 AKT3 ARH12 ARHA C17orf38 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 PDK1 PDPK1 PIK3CG PIK3R5 PIK3R6 PKB PKBG RAC RHO12 RHOA	Homo sapiens (human)
Induction of Cell-Cell Fusion	Angiotensin-converting enzyme 2 Anoctamin-10 Anoctamin-1 Anoctamin-2 Anoctamin-3 Anoctamin-4 Anoctamin-5 Anoctamin-6 Anoctamin-7 Anoctamin-8 Anoctamin-9 Envelope small membrane protein Furin Membrane protein Nucleoprotein ORF3a protein ORF7a protein Spike glycoprotein Transmembrane protease serine 2	A1A5B4 O15393 P09958 P0DTC2 P0DTC3 P0DTC4 P0DTC5 P0DTC7 P0DTC9 Q32M45 Q4KMQ2 Q5XXA6 Q6IWH7 Q75V66 Q9BYF1 Q9BYT9 Q9HCE9 Q9NQ90 Q9NW15	3a 7a ACE2 ANO1 ANO10 ANO2 ANO3 ANO4 ANO5 ANO6 ANO7 ANO8 ANO9 C11orf25 C12orf3 DOG1 E FUR FURIN GDD1 KIAA1623 M N NGEP ORAOV2 PACE PCANAP5 PCSK3 PIG5 PRSS10 S TAOS2 TMEM16A TMEM16B TMEM16C TMEM16D TMEM16E TMEM16F TMEM16G TMEM16H TMEM16J TMEM16K TMPRSS2 TP53I5	Homo sapiens (human)
RAF-independent MAPK1/3 activation	Astrocytic phosphoprotein PEA-15 Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 16 Dual specificity protein phosphatase 1 Dual specificity protein phosphatase 2 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 5 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Dual specificity protein phosphatase 8 Dual specificity protein phosphatase 9 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3	P27361 P28482 P28562 Q05923 Q13115 Q13202 Q15121 Q16690 Q16828 Q16829 Q99956 Q9BY84 Q9Y6W6	C11orf81 CL100 DUSP1 DUSP10 DUSP16 DUSP2 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 ERK1 ERK2 KIAA1700 MAPK1 MAPK3 MKP1 MKP2 MKP3 MKP4 MKP5 MKP7 PAC1 PEA15 PRKM1 PRKM2 PRKM3 PTPN10 PYST1 PYST2 VH1 VH2 VH3 VH5	Homo sapiens (human)
Binding and entry of HIV virion	C-C chemokine receptor type 5 C-X-C chemokine receptor type 4 Envelope glycoprotein gp160 Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Nef Protein Rev Protein Vpr Protein Vpu T-cell surface glycoprotein CD4 Virion infectivity factor	P01730 P04578 P04585 P04591 P04601 P04618 P05919 P51681 P61073 P62937 P69723 P69726	CCR5 CD4 CMKBR5 CXCR4 CYPA PPIA env gag gag-pol nef rev vif vpr vpu	Homo sapiens (human)
Chondroitin sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 11 Carbohydrate sulfotransferase 12 Carbohydrate sulfotransferase 13 Carbohydrate sulfotransferase 15 Carbohydrate sulfotransferase 3 Carbohydrate sulfotransferase 7 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 Chondroitin sulfate glucuronyltransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Chondroitin sulfate synthase 1 Chondroitin sulfate synthase 2 Chondroitin sulfate synthase 3 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q70JA7 Q7LFX5 Q7LGC8 Q86X52 Q8IZ52 Q8N6G5 Q8NET6 Q8TDX6 Q96GW7 Q9NPF2 Q9NRB3 Q9NS84 Q9P2E5	BCAN BEHAB BGN BRAG CALEB CHGN CHGN2 CHPF CHPF2 CHST11 CHST12 CHST13 CHST15 CHST3 CHST7 CHSY CHSY1 CHSY2 CHSY3 CSGALNACT1 CSGALNACT2 CSGLCAT CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 CSS1 CSS2 CSS3 DCN GALNAC4S6ST GALNACT1 GALNACT2 KIAA0598 KIAA0990 KIAA1402 MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN	Homo sapiens (human)
Lipophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Heat shock cognate 71 kDa protein Perilipin-2 Perilipin-3	O43741 O60664 P11142 P54619 P54646 Q99541 Q9UGI9 Q9UGJ0 Q9Y478	ADFP AMPK AMPK2 AMPKG3 HSC70 HSP73 HSPA10 HSPA8 M6PRBP1 PLIN2 PLIN3 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 TIP47	Homo sapiens (human)
Defective ABCB4 causes PFIC3, ICP3 and GBD1	Phosphatidylcholine translocator ABCB4	P21439	ABCB4 MDR3 PGY3	Homo sapiens (human)
Synthesis of PC	Acetylcholinesterase Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Choline O-acetyltransferase Choline kinase alpha Choline transporter-like protein 1 Choline transporter-like protein 2 Choline transporter-like protein 3 Choline transporter-like protein 4 Choline transporter-like protein 5 Choline-phosphate cytidylyltransferase A Choline-phosphate cytidylyltransferase B Choline/ethanolamine kinase Choline/ethanolaminephosphotransferase 1 Cholinephosphotransferase 1 Cholinesterase Lysophosphatidylcholine acyltransferase 1 Phosphatidate phosphatase LPIN1 Phosphatidate phosphatase LPIN2 Phosphatidate phosphatase LPIN3 Phosphatidylcholine transfer protein Phosphatidylethanolamine N-methyltransferase Phosphoethanolamine/phosphocholine phosphatase Phospholipase ABHD3 START domain-containing protein 10 Sodium-dependent lysophosphatidylcholine symporter 1 StAR-related lipid transfer protein 7, mitochondrial	P06276 P19784 P22303 P28329 P35790 P49585 P67870 P68400 Q14693 Q53GD3 Q8IWA5 Q8N4M1 Q8NA29 Q8NCS7 Q8NF37 Q8TCT1 Q8WU67 Q8WUD6 Q8WWI5 Q92539 Q9BQK8 Q9NQZ5 Q9UBM1 Q9UKL6 Q9Y259 Q9Y365 Q9Y5K3 Q9Y6K0	ABHD3 ACHE AYTL2 BCHE C6orf29 CCTB CD92 CDW92 CEPT1 CHAT CHE1 CHETK CHK CHKA CHKB CHKL CHPT1 CK2A1 CK2A2 CK2N CKI CPT1 CSNK2A1 CSNK2A2 CSNK2B CTL1 CTL2 CTL3 CTL4 CTL5 CTPCT G5A GTT1 KIAA0188 KIAA0249 LIPN3L LPCAT1 LPIN1 LPIN2 LPIN3 MFSD2 MFSD2A NG22 NLS1 PCTP PCYT1 PCYT1A PCYT1B PEMPT PEMT PFAAP3 PHOSPHO1 PNMT SDCCAG28 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 STARD10 STARD2 STARD7 TPPT1	Homo sapiens (human)
Thromboxane signalling through TP receptor	Angio-associated migratory cell protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-13 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Thromboxane A2 receptor	O14610 O14775 O60262 O95837 P16520 P21731 P29992 P30679 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q13685 Q14344 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	AAMP GA11 GAQ GNA11 GNA13 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 TBXA2R	Homo sapiens (human)

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