GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1501 - 1525** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Fusion of the Influenza Virion to the Host Cell Endosome	Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821	HA M NA NP NS PA PB1 PB2	Homo sapiens (human)
CD28 dependent PI3K/Akt signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 Membrane protein Mitogen-activated protein kinase kinase kinase 14 Mitogen-activated protein kinase kinase kinase 8 Nucleoprotein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Serine/threonine-protein kinase mTOR T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck	O00459 O15530 P06239 P06241 P0DTC5 P0DTC9 P10747 P27986 P31749 P31751 P33681 P41279 P42081 P42336 P42345 P85299 Q5T1C6 Q6R327 Q92569 Q96RU7 Q99558 Q9BPZ7 Q9BVC4 Q9Y243	AKT1 AKT2 AKT3 C20orf97 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 COT CTMP ESTF FRAP FRAP1 FRAP2 FYN GBL GRB1 KIAA1999 LAB7 LCK LST8 M MAP3K14 MAP3K8 MAPKAP1 MIP1 MLST8 MTOR N NIK NIPK PDK1 PDPK1 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKB PKBG PROTOR1 PRR5 RAC RAFT1 RAPT1 RICTOR SIN1 SKIP3 THEM4 TRB3 TRIB3	Homo sapiens (human)
TRKA activation by NGF	Beta-nerve growth factor High affinity nerve growth factor receptor	P01138 P04629	MTC NGF NGFB NTRK1 TRK TRKA	Homo sapiens (human)
Ca activated K+ channels	Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Calcium-activated potassium channel subunit beta-2 Calcium-activated potassium channel subunit beta-3 Calcium-activated potassium channel subunit beta-4 Intermediate conductance calcium-activated potassium channel protein 4 Small conductance calcium-activated potassium channel protein 1 Small conductance calcium-activated potassium channel protein 2 Small conductance calcium-activated potassium channel protein 3	O15554 Q12791 Q16558 Q86W47 Q92952 Q9H2S1 Q9NPA1 Q9UGI6 Q9Y691	IK1 IKCA1 K3 KCA4 KCNMA KCNMA1 KCNMB1 KCNMB2 KCNMB3 KCNMB4 KCNMBL KCNN1 KCNN2 KCNN3 KCNN4 SK SK4 SLO	Homo sapiens (human)
MPS II - Hunter syndrome	Iduronate 2-sulfatase	P22304	IDS SIDS	Homo sapiens (human)
Virion Assembly and Release	Envelope small membrane protein Membrane protein Nucleoprotein ORF3a protein ORF7a protein Spike glycoprotein	P0DTC2 P0DTC3 P0DTC4 P0DTC5 P0DTC7 P0DTC9	3a 7a E M N S	Homo sapiens (human)
CTNNB1 T41 mutants aren't phosphorylated	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Catenin beta-1 Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P35222 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 CTNNB CTNNB1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX	Homo sapiens (human)
NOTCH4 Intracellular Domain Regulates Transcription	Actin, aortic smooth muscle CREB-binding protein Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Mothers against decapentaplegic homolog 3 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 4 Recombining binding protein suppressor of hairless SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Vascular endothelial growth factor receptor 3	P35916 P46531 P62736 P84022 Q04721 Q06330 Q09472 Q13495 Q13573 Q14469 Q5TA89 Q8IZL2 Q92585 Q92793 Q92830 Q92831 Q96JK9 Q99466 Q9UBP5 Q9Y5J3	ACTA2 ACTSA ACTVS BHLHB31 BHLHB32 BHLHB38 BHLHB39 CBP CG1 CHF1 CHF2 CREBBP CXorf6 EP300 FLT4 GCN5 GCN5L2 GRL HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HL HRT1 HRT2 HRY IGKJRB IGKJRB1 INT3 KAT2A KAT2B KIAA0200 KIAA1816 KIAA1819 MADH3 MAML1 MAML2 MAML3 MAMLD1 NOTCH1 NOTCH2 NOTCH4 P300 PCAF RBPJ RBPJK RBPSUH SKIIP SKIP SMAD3 SNW1 TAN1 VEGFR3	Homo sapiens (human)
VxPx cargo-targeting to cilium	ADP-ribosylation factor 4 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Cyclic nucleotide-gated channel alpha-2 Cyclic nucleotide-gated channel alpha-4 Cyclic nucleotide-gated channel beta-1 Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 4 Exocyst complex component 5 Exocyst complex component 6 Exocyst complex component 7 Exocyst complex component 8 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Polycystin-1 Polycystin-2 Rab-3A-interacting protein Rab11 family-interacting protein 3 Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	O00471 O60645 O75154 P08100 P18085 P61006 P62491 P98161 Q13563 Q14028 Q16280 Q8IV77 Q8IYI6 Q8TAG9 Q92538 Q96A65 Q96KP1 Q96QF0 Q9NV70 Q9ULH1 Q9UPT5	ARF2 ARF4 ARFO1 ASAP1 CNCA CNCA1 CNCG2 CNCG3L CNCG4 CNGA2 CNGA4 CNGB1 DDEF1 EXO70 EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6 EXOC7 EXOC8 GBF1 KIAA0248 KIAA0665 KIAA1067 KIAA1249 KIAA1699 MEL OPN2 PAG2 PKD1 PKD2 RAB11 RAB11A RAB11FIP3 RAB3IP RAB8 RAB8A RABIN8 RCNC2 RHO SEC10 SEC10L1 SEC15A SEC15L SEC15L1 SEC3 SEC3L1 SEC5 SEC5L1 SEC6 SEC6L1 SEC8 SEC8L1 TRPP2	Homo sapiens (human)
The fatty acid cycling model	Brain mitochondrial carrier protein 1 Dicarboxylate carrier SLC25A8 Mitochondrial brown fat uncoupling protein 1 Mitochondrial uncoupling protein 4 Putative mitochondrial transporter UCP3	O95258 O95847 P25874 P55851 P55916	BMCP1 SLC25A14 SLC25A27 SLC25A7 SLC25A8 SLC25A9 UCP UCP1 UCP2 UCP3 UCP4 UCP5	Homo sapiens (human)
Mitochondrial short-chain enoyl-CoA hydratase deficiency 1	Enoyl-CoA hydratase, mitochondrial	P30084	ECHS1	Homo sapiens (human)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9	O15520 P05230 P08620 P09038 P10767 P11487 P19174 P31371 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 PLC1 PLCG1	Homo sapiens (human)
Regulation of FZD by ubiquitination	E3 ubiquitin-protein ligase RNF43 E3 ubiquitin-protein ligase ZNRF3 Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-8 Leucine-rich repeat-containing G-protein coupled receptor 4 Leucine-rich repeat-containing G-protein coupled receptor 5 Leucine-rich repeat-containing G-protein coupled receptor 6 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Polyubiquitin-B Polyubiquitin-C Protein Wnt-3a R-spondin-1 R-spondin-2 R-spondin-3 R-spondin-4 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60353 O75197 O75473 O75581 P0CG47 P0CG48 P40818 P56704 P62979 P62987 Q13467 Q2I0M5 Q2MKA7 Q68DV7 Q6UXX9 Q9BXB1 Q9BXY4 Q9H461 Q9HBX8 Q9ULT6 Q9ULV1	C20orf182 C2orf31 FZD4 FZD5 FZD6 FZD8 GPR48 GPR49 GPR67 KIAA0055 KIAA1133 LGR4 LGR5 LGR6 LR3 LRP5 LRP6 LRP7 PWTSR RNF203 RNF43 RPS27A RSPO1 RSPO2 RSPO3 RSPO4 THSD2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBPY USP8 WNT3A ZNRF3	Homo sapiens (human)
RAC1 GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin remodeling regulator NHS Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Active breakpoint cluster region-related protein Alsin Amphoterin-induced protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 BAR/IMD domain-containing adapter protein 2-like 1 BAR/IMD domain-containing adapter protein 2 Beta-chimaerin Breakpoint cluster region protein Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 4 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Citron Rho-interacting kinase Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 DEP domain-containing protein 1B Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 11 Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Dedicator of cytokinesis protein 5 Dedicator of cytokinesis protein 6 Dedicator of cytokinesis protein 7 Dedicator of cytokinesis protein 8 Dedicator of cytokinesis protein 9 Delta(14)-sterol reductase LBR Differentially expressed in FDCP 6 homolog Emerin Ephexin-1 Ephrin type-A receptor 2 Erbin Extended synaptotagmin-1 FERM, ARHGEF and pleckstrin domain-containing protein 1 FERM, ARHGEF and pleckstrin domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 5 Fermitin family homolog 2 Formin-like protein 1 GEM-interacting protein Granule associated Rac and RHOG effector protein 1 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Inner nuclear membrane protein Man1 Integrin beta-1 Kalirin Kinectin Lamina-associated polypeptide 2, isoforms beta/gamma MAGUK p55 subfamily member 7 N-chimaerin NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase activator 1 NADPH oxidase organizer 1 Nck-associated protein 1-like Nck-associated protein 1 Neutral amino acid transporter B(0) Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Nischarin Oligophrenin-1 Partitioning defective 6 homolog alpha Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phospholipase D1 Phospholipase D2 Pleckstrin homology domain-containing family G member 1 Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 3 Pleckstrin homology domain-containing family G member 6 Protein BRICK1 Protein ECT2 Protein FAM13A Protein FAM13B Protein diaphanous homolog 3 Protein jagged-1 Proto-oncogene DBL Proto-oncogene vav Puratrophin-1 Rac GTPase-activating protein 1 Ragulator complex protein LAMTOR1 RalA-binding protein 1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP2 Ras GTPase-activating-like protein IQGAP3 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-7a Ras-specific guanine nucleotide-releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GTPase-activating protein 10 Rho GTPase-activating protein 12 Rho GTPase-activating protein 15 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 20 Rho GTPase-activating protein 21 Rho GTPase-activating protein 22 Rho GTPase-activating protein 23 Rho GTPase-activating protein 24 Rho GTPase-activating protein 25 Rho GTPase-activating protein 26 Rho GTPase-activating protein 27 Rho GTPase-activating protein 29 Rho GTPase-activating protein 30 Rho GTPase-activating protein 31 Rho GTPase-activating protein 32 Rho GTPase-activating protein 33 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 42 Rho GTPase-activating protein 44 Rho GTPase-activating protein 45 Rho GTPase-activating protein 4 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho GTPase-activating protein 9 Rho GTPase-activating protein SYDE2 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 18 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 4 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor TIAM1 Rho guanine nucleotide exchange factor TIAM2 SH3 domain-binding protein 1 SLIT-ROBO Rho GTPase-activating protein 1 SLIT-ROBO Rho GTPase-activating protein 2 SLIT-ROBO Rho GTPase-activating protein 3 Serine/threonine-protein kinase MRCK alpha Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase PAK 6 Serine/threonine-protein kinase TAO3 Serine/threonine-protein kinase VRK2 Son of sevenless homolog 1 Son of sevenless homolog 2 Spermatogenesis-associated protein 13 Switch-associated protein 70 Synaptobrevin homolog YKT6 Synaptosomal-associated protein 23 T-cell activation Rho GTPase-activating protein Transferrin receptor protein 1 Triple functional domain protein Tyrosine-protein kinase ABL2 Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3 WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A1A4S6 A1L390 A6NGB9 A6NI28 A7KAX9 O00161 O00401 O00459 O14559 O14578 O14827 O14939 O15013 O15063 O15068 O15085 O15498 O43295 O43516 O60229 O60890 O75044 O75914 O75962 O94887 O94988 O94989 O95466 O96013 P02786 P04839 P05556 P10911 P11274 P13498 P14598 P15498 P15882 P19878 P27986 P29317 P42167 P42331 P42336 P42684 P42768 P43121 P46940 P50402 P51149 P52565 P52566 P52735 P52757 P55160 P60953 P63000 P78504 P98171 Q00587 Q03135 Q07889 Q07890 Q07960 Q12774 Q12979 Q13009 Q13017 Q13153 Q13177 Q13393 Q13459 Q13576 Q14155 Q14161 Q14185 Q14344 Q14739 Q15052 Q15080 Q15311 Q15758 Q15836 Q16512 Q16513 Q17R89 Q2M1Z3 Q3KR16 Q52LW3 Q53QZ3 Q58EX7 Q5JSL3 Q5T2T1 Q5T5U3 Q5VT25 Q5VT97 Q68EM7 Q6IAA8 Q6T4R5 Q6ZNL6 Q6ZSZ5 Q6ZUM4 Q70Z35 Q7L576 Q7Z5H3 Q7Z6B7 Q7Z6I6 Q86SJ2 Q86UP2 Q86UR1 Q86VI3 Q86VW2 Q86Y07 Q8IVF5 Q8IW93 Q8IWW6 Q8IZD9 Q8IZP0 Q8N103 Q8N1I0 Q8N264 Q8N4T4 Q8N5V2 Q8NF50 Q8NFA2 Q8TAA9 Q8TCU6 Q8TF74 Q8WUW1 Q8WUY9 Q8WWN8 Q8WZ64 Q92558 Q92569 Q92608 Q92619 Q96AC1 Q96BY6 Q96F07 Q96HP0 Q96N67 Q96N96 Q96P48 Q96Q42 Q96QB1 Q96RT1 Q9BRR9 Q9BSJ8 Q9BZ29 Q9C0H5 Q9H0H5 Q9H2K8 Q9H3Q1 Q9H4E7 Q9H7D0 Q9H7P9 Q9H8V3 Q9HBY0 Q9NPB6 Q9NQU5 Q9NR80 Q9NRY4 Q9NSV4 Q9NYB9 Q9NYF5 Q9P107 Q9P227 Q9P286 Q9P2F6 Q9UH65 Q9UHR4 Q9UKW4 Q9ULL1 Q9UNA1 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y2I1 Q9Y2U8 Q9Y2X7 Q9Y3L3 Q9Y4F1 Q9Y5S8 Q9Y6W5	ABI1 ABI2 ABL2 ABLL ABR ALI1 ALS2 ALS2CR6 AMIGO2 ARAP1 ARAP2 ARAP3 ARG ARGBPIA ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP13 ARHGAP14 ARHGAP15 ARHGAP17 ARHGAP2 ARHGAP20 ARHGAP21 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP25 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP3 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP34 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP7 ARHGAP9 ARHGDIA ARHGDIB ARHGEF10 ARHGEF11 ARHGEF15 ARHGEF18 ARHGEF19 ARHGEF25 ARHGEF39 ARHGEF4 ARHGEF5 ARHGEF6 ARHGEF7 ASCT2 BAIAP2 BAIAP2L1 BCH BCR BCR1 BORG4 BORG5 BRK1 C11orf59 C17orf1 C17orf1B C3orf10 C5orf5 C9orf100 CAMGAP1 CAV CAV1 CDC42 CDC42BPA CDC42EP1 CDC42EP4 CDC42GAP CDEP CDGAP CENTD1 CENTD2 CENTD3 CEP1 CEP4 CG1 CHN CHN1 CHN2 CIT COOL1 COOL2 CR16 CRIK CYBA CYBB CYFIP1 CYFIP2 D22S11 DBL DEF6 DEPDC1B DEPDC2 DIAP3 DIAPH3 DLC1 DOCK1 DOCK10 DOCK11 DOCK2 DOCK3 DOCK4 DOCK5 DOCK6 DOCK7 DOCK8 DOCK9 DPK DUET DUO ECK ECT2 EDMD EMD EPHA2 ERBB2IP ERBIN ESYT1 FAM13A FAM13A1 FAM13B FAM13B1 FAM62A FARP1 FARP2 FERMT2 FGD5 FILGAP FMNL FMNL1 FNBP2 FNRB FRL1 GARRE1 GDIA1 GDIA2 GDID4 GEFT GIT1 GIT2 GMIP GNA13 GRAF GRAF2 GRAF3 GRB1 GRF1 GRF2 GRIT GRLF1 HAPIP HEM1 HEM2 HMHA1 IBP IMD2 IQGAP1 IQGAP2 IQGAP3 IRAS IRTKS ITGB1 JAG1 JAGL1 JIK KALRN KDS KIAA0004 KIAA0006 KIAA0051 KIAA0053 KIAA0068 KIAA0131 KIAA0142 KIAA0148 KIAA0209 KIAA0223 KIAA0269 KIAA0294 KIAA0299 KIAA0355 KIAA0362 KIAA0380 KIAA0411 KIAA0451 KIAA0456 KIAA0521 KIAA0580 KIAA0587 KIAA0599 KIAA0621 KIAA0640 KIAA0672 KIAA0694 KIAA0712 KIAA0716 KIAA0747 KIAA0782 KIAA0793 KIAA0900 KIAA0914 KIAA0915 KIAA0949 KIAA0975 KIAA1058 KIAA1112 KIAA1142 KIAA1156 KIAA1168 KIAA1204 KIAA1209 KIAA1225 KIAA1264 KIAA1304 KIAA1391 KIAA1395 KIAA1415 KIAA1424 KIAA1478 KIAA1501 KIAA1563 KIAA1688 KIAA1722 KIAA1723 KIAA1771 KIAA2016 KIND2 KTN1 LAMTOR1 LAP2 LBR LEMD3 M7V1 MAN1 MAP3K18 MBC2 MCAM MCF2 MCF2L MDF2 MEGAP MGCRACGAP MIG2 MOCA MOX1 MOX2 MPP7 MSE55 MSK12 MUC18 MYO9B MYR5 NAP1 NCF1 NCF2 NCF4 NCKAP1 NCKAP1L NGEF NHS NISCH NOH1 NOX1 NOX2 NOX3 NOXA1 NOXA2 NOXO1 NOXO2 OPHN1 OPHN1L OPHN3 OST P190A P41NOX P51NOX P67PHOX P85SPR PAK1 PAK2 PAK3 PAK3BP PAK4 PAK5 PAK6 PAK7 PAR6A PARD6A PARG1 PDRO PIK3CA PIK3R1 PIK3R2 PIK3R3 PIR121 PIXA PIXB PKN PKN1 PKN2 PLD1 PLD2 PLEKHC1 PLEKHC2 PLEKHC3 PLEKHG1 PLEKHG2 PLEKHG3 PLEKHG4 PLEKHG6 PREX1 PREX2 PRK1 PRK2 PRKCL1 PRKCL2 PRTPHN1 RAB7 RAB7A RAC1 RACGAP1 RALBP1 RAP1GN1 RASGRF2 RDR RDRC RGC1 RHOGAP1 RHOGAP2 RHOGAP4 RHOGAP5 RICH1 RICH2 RICS RLIP RLIP1 RLIP76 SCAR1 SCAR3 SH3BP1 SH3D20 SH3PXD1A SH3PXD4 SH3PXD5 SLC1A5 SNAP23 SNX26 SOS1 SOS2 SPATA13 SRGAP1 SRGAP2 SRGAP2A SRGAP3 SSH3BP1 STA STARD12 STB2 STEF STK21 SWAP70 SYB3 SYDE2 TAGAP TAGAP1 TAOK3 TC25 TCGAP TFRC TIAM1 TIAM2 TIM TMEM133 TMPO TRAD TRIO VAMP3 VANGL1 VAV VAV1 VAV2 VAV3 VRK2 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE XTP8 YKT6 ZFYVE23 ZIZ1 ZIZ2 ZIZ3 p190ARHOGAP	Homo sapiens (human)
Regulation of gene expression in beta cells	DNA-binding protein RFX6 Forkhead box protein O1 Hepatocyte nuclear factor 1-alpha Hepatocyte nuclear factor 3-beta Hepatocyte nuclear factor 3-gamma Hepatocyte nuclear factor 4-gamma Hexokinase-4 Homeobox protein Nkx-2.2 Homeobox protein Nkx-6.1 Insulin Islet amyloid polypeptide Neurogenic differentiation factor 1 Paired box protein Pax-6 Pancreas/duodenum homeobox protein 1 Solute carrier family 2, facilitated glucose transporter member 2 Transcription factor MafA	O95096 P01308 P10997 P11168 P20823 P26367 P35557 P52945 P55318 P78426 Q12778 Q13562 Q14541 Q8HWS3 Q8NHW3 Q9Y261	AN2 BHLHA3 FKHR FOXA2 FOXA3 FOXO1 FOXO1A GCK GLUT2 HNF1A HNF3B HNF3G HNF4G IAPP INS IPF1 MAFA NEUROD NEUROD1 NKX2-2 NKX2.2 NKX2B NKX6-1 NKX6A NR2A2 PAX6 PDX1 RFX6 RFXDC1 SLC2A2 STF1 TCF1 TCF3B TCF3G	Homo sapiens (human)
Passive transport by Aquaporins	Aquaporin-10 Aquaporin-11 Aquaporin-12A Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin-6 Aquaporin-7 Aquaporin-8 Aquaporin-9 Lens fiber major intrinsic protein	O14520 O43315 O94778 P29972 P30301 P41181 P55064 P55087 Q13520 Q8IXF9 Q8NBQ7 Q92482 Q96PS8	AQP0 AQP1 AQP10 AQP11 AQP12 AQP12A AQP2 AQP2L AQP3 AQP4 AQP5 AQP6 AQP7 AQP7L AQP8 AQP9 AQPX1 AQPX2 CHIP28 MIP SSC1	Homo sapiens (human)
Branched-chain ketoacid dehydrogenase kinase deficiency	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Branched-chain alpha-ketoacid dehydrogenase kinase Dihydrolipoyl dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial	O14874 P09622 P11182 P12694 P21953	BCATE2 BCKDHA BCKDHB BCKDHE2 BCKDK DBT DLD GCSL LAD PHE3	Homo sapiens (human)
Nuclear Receptor transcription pathway	Androgen receptor COUP transcription factor 1 Estrogen receptor beta Estrogen receptor Estrogen-related receptor gamma Hepatocyte nuclear factor 4-alpha Hepatocyte nuclear factor 4-gamma Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor 2C2-associated protein Nuclear receptor ROR-alpha Nuclear receptor ROR-beta Nuclear receptor ROR-gamma Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Nuclear receptor subfamily 0 group B member 2 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor subfamily 1 group D member 2 Nuclear receptor subfamily 2 group C member 1 Nuclear receptor subfamily 2 group C member 2 Nuclear receptor subfamily 2 group E member 1 Nuclear receptor subfamily 2 group F member 6 Nuclear receptor subfamily 4 group A member 2 Nuclear receptor subfamily 4immunitygroup A member 1 Nuclear receptor-binding protein Oxysterols receptor LXR-beta Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor delta Peroxisome proliferator-activated receptor gamma Progesterone receptor Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Retinoic acid receptor RXR-gamma Retinoic acid receptor alpha Retinoic acid receptor beta Retinoic acid receptor gamma Steroid hormone receptor ERR1 Steroid hormone receptor ERR2 Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	O75376 O95718 P03372 P06401 P10275 P10276 P10588 P10589 P10826 P10827 P10828 P11473 P11474 P13056 P13631 P19793 P20393 P22736 P28702 P35398 P37231 P41235 P43354 P48443 P49116 P51449 P55055 P62508 Q03181 Q07869 Q13285 Q14541 Q14995 Q15466 Q15648 Q86WQ0 Q92731 Q92753 Q9UHY1 Q9Y466 Q9Y618	AD4BP AR ARC205 BCON3 CRSP1 CRSP200 CTG26 DHTR DRIP205 DRIP230 EAR1 EAR2 EAR3 EAR7 ERBA1 ERBA2 ERBAL2 ERBAL3 ERR1 ERR3 ERRB2 ERRG2 ESR ESR1 ESR2 ESRL1 ESRL2 ESRRA ESRRB ESRRG ESTRB FTZF1 GFRP1 HAP HMR HNF4 HNF4A HNF4G HREV KIAA0832 KIAA1047 LXRB MED1 NAK1 NCOR1 NCOR2 NER NOT NR0B2 NR1A1 NR1A2 NR1B1 NR1B2 NR1B3 NR1C1 NR1C2 NR1C3 NR1D1 NR1D2 NR1F1 NR1F2 NR1F3 NR1H2 NR1I1 NR2A1 NR2A2 NR2B1 NR2B2 NR2B3 NR2C1 NR2C2 NR2C2AP NR2E1 NR2F1 NR2F6 NR3A1 NR3A2 NR3B1 NR3B2 NR3B3 NR3C3 NR3C4 NR4A1 NR4A2 NR5A1 NRBP NRBP1 NURR1 PBP PGR PPAR PPARA PPARB PPARBP PPARD PPARG PPARGBP RARA RARB RARG RB18A RORA RORB RORC RORG RXRA RXRB RXRG RZRA RZRB RZRG SF1 SHP TAK1 TCF14 TFCOUP1 THR1 THRA THRA1 THRA2 THRAL THRB TINUR TLX TR2 TR4 TRA16 TRAP220 TRIP2 UNR VDR	Homo sapiens (human)
DSCAM interactions	Cell adhesion molecule DSCAM Cell adhesion molecule DSCAML1 Netrin receptor DCC Netrin-1	O60469 O95631 P43146 Q8TD84	DCC DSCAM DSCAM2 DSCAML1 IGDCC1 KIAA1132 NTN1 NTN1L	Homo sapiens (human)
Defective ABCD1 causes ALD	ATP-binding cassette sub-family D member 1	P33897	ABCD1 ALD	Homo sapiens (human)
MyD88 deficiency (TLR5)	Flagellin Myeloid differentiation primary response protein MyD88 Toll-like receptor 5	O60602 P04949 Q99836	MYD88 TIL3 TLR5 flaF fliC hag	Homo sapiens (human)
Interleukin-35 Signalling	Calnexin Interleukin-12 receptor subunit beta-2 Interleukin-12 subunit alpha Interleukin-27 receptor subunit alpha Interleukin-27 subunit beta Interleukin-6 receptor subunit beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 P23458 P27824 P29459 P29597 P40189 P40763 P42224 Q14213 Q14765 Q6UWB1 Q99665	APRF CANX CRL1 EBI3 IL12A IL12RB2 IL27B IL27RA IL6ST JAK1 JAK1A JAK1B JAK2 NKSF1 STAT1 STAT3 STAT4 TCCR TYK2 WSX1	Homo sapiens (human)
RHO GTPases Activate Rhotekin and Rhophilins	Protein lin-7 homolog B Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Rhophilin-1 Rhophilin-2 Rhotekin Ropporin-1A Tax1-binding protein 3 Transforming protein RhoA	O14907 P08134 P61586 P62745 Q8IUC4 Q8TCX5 Q9BST9 Q9HAP6 Q9HAT0	ARH12 ARH6 ARH9 ARHA ARHB ARHC KIAA1929 LIN7B MALS2 RHO12 RHOA RHOB RHOC RHPN1 RHPN2 ROPN1 ROPN1A RTKN RTKN1 TAX1BP3 TIP1 VELI2	Homo sapiens (human)
Xenobiotics	Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Cytochrome P450 1A1 Cytochrome P450 2A13 Cytochrome P450 2A6 Cytochrome P450 2A7 Cytochrome P450 2B6 Cytochrome P450 2C18 Cytochrome P450 2C19 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 2E1 Cytochrome P450 2F1 Cytochrome P450 2J2 Cytochrome P450 2S1 Cytochrome P450 2W1 Cytochrome P450 3A43 Cytochrome P450 3A4 Cytochrome P450 3A5 Cytochrome P450 3A7	A9YTQ3 P04798 P05181 P08684 P10632 P10635 P11509 P11712 P20813 P20815 P20853 P24462 P24903 P27540 P33260 P33261 P35869 P51589 Q16696 Q8TAV3 Q96SQ9 Q9HB55 Q9HBZ2	AHR AHRR ARNT ARNT2 BHLHE1 BHLHE2 BHLHE76 BHLHE77 CYP1A1 CYP2A13 CYP2A3 CYP2A6 CYP2A7 CYP2B6 CYP2C10 CYP2C18 CYP2C19 CYP2C8 CYP2C9 CYP2D6 CYP2DL1 CYP2E CYP2E1 CYP2F1 CYP2J2 CYP2S1 CYP2W1 CYP3A3 CYP3A4 CYP3A43 CYP3A5 CYP3A7 KIAA0307 KIAA1234	Homo sapiens (human)
PKMTs methylate histone lysines	Actin-histidine N-methyltransferase Activating transcription factor 7-interacting protein 1 Histone H3.1 Histone H3.2 Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase 2A Histone-lysine N-methyltransferase 2B Histone-lysine N-methyltransferase 2C Histone-lysine N-methyltransferase 2D Histone-lysine N-methyltransferase ASH1L Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase KMT5B Histone-lysine N-methyltransferase KMT5C Histone-lysine N-methyltransferase MECOM Histone-lysine N-methyltransferase NSD2 Histone-lysine N-methyltransferase NSD3 Histone-lysine N-methyltransferase PRDM16 Histone-lysine N-methyltransferase PRDM9 Histone-lysine N-methyltransferase SETD1A Histone-lysine N-methyltransferase SETD1B Histone-lysine N-methyltransferase SETD2 Histone-lysine N-methyltransferase SETD7 Histone-lysine N-methyltransferase SETDB1 Histone-lysine N-methyltransferase SETDB2 Histone-lysine N-methyltransferase SMYD3 Histone-lysine N-methyltransferase SUV39H1 Histone-lysine N-methyltransferase SUV39H2 Histone-lysine N-methyltransferase, H3 lysine-36 specific Histone-lysine N-methyltransferase, H3 lysine-79 specific N-lysine methyltransferase KMT5A N-lysine methyltransferase SETD6 N-lysine methyltransferase SMYD2 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Polycomb protein EED Polycomb protein SUZ12 Protein dpy-30 homolog Retinoblastoma-binding protein 5 Set1/Ash2 histone methyltransferase complex subunit ASH2 Transcription factor p65 WD repeat-containing protein 5 Zinc finger protein AEBP2	O14686 O15047 O43463 O75530 O96028 P19838 P61964 P62805 P68431 Q00653 Q03112 Q03164 Q04206 Q09028 Q15022 Q15047 Q15291 Q15910 Q16576 Q4FZB7 Q6VMQ6 Q6ZN18 Q71DI3 Q86TU7 Q86Y97 Q8NEZ4 Q8TBK2 Q8TEK3 Q8WTS6 Q96KQ7 Q96L73 Q96T68 Q9BYW2 Q9BZ95 Q9C005 Q9H5I1 Q9H7B4 Q9H9B1 Q9HAZ2 Q9NQR1 Q9NQV7 Q9NR48 Q9NRG4 Q9UBL3 Q9UMN6 Q9UPS6	AEBP2 ALL1 ALR ARA267 ASH1L ASH2L ASH2L1 ATF7IP BAT8 BIG3 C13orf4 C14orf154 C6orf30 CHET9 CLLD8 CXXC7 DOT1L DPY30 EED EHMT1 EHMT2 ESET EUHMTASE1 EVI1 EZH2 G9A GLP H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HALR HIF1 HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST4H4 HRX HRX2 HTRX HYPB JJAZ1 KIAA0067 KIAA0160 KIAA0304 KIAA0339 KIAA1076 KIAA1090 KIAA1420 KIAA1506 KIAA1675 KIAA1717 KIAA1732 KIAA1814 KIAA1876 KMT1A KMT1B KMT1C KMT1D KMT1E KMT1F KMT2A KMT2B KMT2C KMT2D KMT2F KMT2G KMT2H KMT3A KMT3B KMT3C KMT4 KMT5A KMT5B KMT5C KMT6 KMT7 LYT10 MCAF MCAF1 MDS1 MECOM MEL1 MLL MLL1 MLL2 MLL3 MLL4 MMSET NFKB1 NFKB2 NFKB3 NG36 NSD1 NSD2 NSD3 PFM13 PFM6 PRDM16 PRDM3 PRDM9 PRSET7 RBAP46 RBAP48 RBBP4 RBBP5 RBBP7 RBQ3 RELA SET07 SET1 SET1A SET1B SET2 SET7 SET8 SET9 SETD1A SETD1B SETD2 SETD3 SETD6 SETD7 SETD8 SETDB1 SETDB2 SMYD2 SMYD3 SUV39H SUV39H1 SUV39H2 SUV420H1 SUV420H2 SUZ12 TRX1 TRX2 TRX5 WBP7 WDR5 WHSC1 WHSC1L1 ZMYND1 ZNFN3A1	Homo sapiens (human)

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