GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (9988) Glycans (5831) Glycoproteins (15733) Lectins (298) Pathways (2074)

Displaying entries **826 - 850** of **2074** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol
Scavenging by Class H Receptors	Apolipoprotein B-100 SPARC Stabilin-1 Stabilin-2	P04114 P09486 Q8WWQ8 Q9NY15	APOB FEEL1 FEEL2 FELL FEX2 HARE KIAA0246 ON SPARC STAB1 STAB2
Transport of fatty acids	Apolipoprotein D Epididymal-specific lipocalin-12 Epididymal-specific lipocalin-9 Lipocalin-15 Lipocalin-1 Long-chain fatty acid transport protein 1 Long-chain fatty acid transport protein 4 Long-chain fatty acid transport protein 6	P05090 P31025 Q6JVE5 Q6P1M0 Q6PCB7 Q6UWW0 Q8WX39 Q9Y2P4	ACSVL2 ACSVL4 ACSVL5 APOD FACVL2 FATP1 FATP4 FATP6 LCN1 LCN12 LCN15 LCN9 SLC27A1 SLC27A4 SLC27A6 VEGP
Nuclear signaling by ERBB4	Apolipoprotein E Arf-GAP with dual PH domain-containing protein 1 Beta-casein Disintegrin and metalloproteinase domain-containing protein 17 Estrogen receptor Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Glial fibrillary acidic protein Max dimerization protein 4 Nicastrin Nuclear receptor corepressor 1 Presenilin-1 Presenilin-2 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Progesterone receptor Proheparin-binding EGF-like growth factor Protein S100-B Proto-oncogene tyrosine-protein kinase Src SPARC Signal transducer and activator of transcription 5A Stathmin Stromal cell-derived factor 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 Transcriptional coactivator YAP1 WW domain-containing oxidoreductase	O14511 O14944 O75376 O75689 P02649 P03372 P04271 P05814 P06401 P09486 P12931 P14136 P16949 P35070 P42229 P46937 P48061 P49768 P49810 P56975 P78536 Q02297 Q14582 Q8WW43 Q8WWG1 Q92542 Q96BI3 Q99075 Q9NYJ8 Q9NZ42 Q9NZC7	AD3 AD4 ADAM17 ADAP1 APH1A APH1B APOE BHLHC12 BTC C1orf215 CASB CENTA1 CSN2 CSVP CXCL12 DTR DTS EREG ESR ESR1 FOR GFAP GGF HBEGF HEGFL HGL HRGA KIAA0253 KIAA0733 KIAA1047 LAP18 MAD4 MAP3K7IP2 MXD4 NCOR1 NCSTN NDF NR3A1 NR3C3 NRG1 NRG2 NRG3 NRG4 NTAK ON OP18 PEN2 PGR PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 S100B SDF1 SDF1A SDF1B SDR41C1 SMDF SPARC SRC SRC1 STAT5 STAT5A STM2 STMN1 TAB2 TACE WOX1 WWOX YAP1 YAP65
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	Apolipoprotein E Protein DEK Transcription factor AP-2-alpha	P02649 P05549 P35659	AP2TF APOE DEK TFAP2 TFAP2A
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Apoptosis facilitator Bcl-2-like protein 14 Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 B-cell lymphoma 6 protein Baculoviral IAP repeat-containing protein 5 Cellular tumor antigen p53 Geranylgeranyl transferase type-2 subunit alpha Geranylgeranyl transferase type-2 subunit beta Protein NDRG1 Quinone oxidoreductase PIG3 Rab proteins geranylgeranyltransferase component A 1 Tumor protein 63 Tumor protein p73 p53 apoptosis effector related to PMP-22	O15350 O15392 P04637 P24386 P41182 P53611 Q13625 Q53FA7 Q92597 Q92696 Q96FX8 Q96KQ4 Q9BZR8 Q9H3D4	API4 ASPP1 ASPP2 BBP BCL2L14 BCL5 BCL6 BCLG BIRC5 CAP43 CHM DRG1 GGTB IAP4 KCP1 KET KIAA0771 KRTCAP1 LAZ3 NDRG1 P53 P63 P73 P73H P73L PERP PIG3 PIGPC1 PPP1R13B RABGGTA RABGGTB REP1 RTP TCD THW TP53 TP53BP2 TP53I3 TP63 TP73 TP73L ZBTB27 ZNF51
Suppression of apoptosis	Apoptosis inhibitor Rv3654c Apoptosis inhibitor Rv3655c Cathepsin G E3 ubiquitin-protein ligase RNF213 Glycogen synthase kinase-3 alpha Low molecular weight protein-tyrosine phosphatase A Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Possible Mce-family lipoprotein LprM (Mce-family lipoprotein Mce3E) Serine protease inhibitor Rv3364c Splicing factor, proline- and glutamine-rich Zinc finger protein RFP	O50393 O53971 O69622 O69623 P08311 P14373 P23246 P27361 P28482 P49840 P9WIA1 Q63HN8	ALO17 C17orf27 CTSG ERK1 ERK2 GSK3A KIAA1554 KIAA1618 MAPK1 MAPK3 MYSTR PRKM1 PRKM2 PRKM3 PSF RFP RNF213 RNF76 Rv3364c Rv3654c Rv3655c SFPQ TRIM27 lprM mce3E mptpA ptpA
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	Apoptosis regulator BAX Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 CREB-binding protein Cellular tumor antigen p53 Ferroptosis suppressor protein 1 Metalloreductase STEAP3 PRELI domain containing protein 3A PRELI domain-containing protein 1, mitochondrial Phorbol-12-myristate-13-acetate-induced protein 1 Serine-protein kinase ATM TP53-regulated inhibitor of apoptosis 1 Tumor protein 63 Tumor protein p53-inducible nuclear protein 1 Tumor protein p73 Zinc finger protein 420 p53-regulated apoptosis-inducing protein 1	O15350 O43715 O60238 P04637 P55957 Q07812 Q13315 Q13625 Q13794 Q658P3 Q8TAQ5 Q92793 Q96A56 Q96KQ4 Q96N28 Q9BRQ8 Q9BXH1 Q9H3D4 Q9HCN2 Q9Y255	15E1.1 AIFM2 AMID ASPP1 ASPP2 ATM BAX BBC3 BBP BCL2L4 BID BNIP3A BNIP3H BNIP3L C18orf43 CBP CREBBP KET KIAA0771 NIX NOXA P53 P53DINP1 P63 P73 P73H P73L PMAIP1 PPP1R13B PRELI PRELID1 PRELID3A PRG3 PUMA SIP SLMO1 STEAP3 TP53 TP53AIP1 TP53BP2 TP53INP1 TP63 TP73 TP73L TRIAP1 TSAP6 ZNF420
Activation, translocation and oligomerization of BAX	Apoptosis regulator BAX BH3-interacting domain death agonist	P55957 Q07812	BAX BCL2L4 BID
Pyroptosis	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Caspase-1 Caspase-3 Caspase-4 Caspase-5 Cellular tumor antigen p53 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c Gasdermin-D Gasdermin-E Granzyme B High mobility group protein B1 Interferon regulatory factor 1 Interferon regulatory factor 2 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Neutrophil elastase Tumor protein 63	O43633 O60443 P01583 P01584 P04637 P08246 P09429 P10144 P10914 P14316 P29466 P42574 P49662 P51878 P57764 P99999 Q07812 Q14116 Q16611 Q8WUX9 Q96CF2 Q96FZ7 Q9BY43 Q9H3D4 Q9H444 Q9UQN3 Q9Y3E7	BAK BAK1 BAX BC2 BCL2L4 BCL2L7 C14orf123 C20orf178 CASP1 CASP3 CASP4 CASP5 CDN1 CGI149 CGL1 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CPP32 CSPB CTLA1 CYC CYCS DFNA5 DFNA5L ELA2 ELANE GRB GSDMD GSDMDC1 GSDME GZMB HMG1 HMGB1 ICERE1 ICH2 ICH3 IGIF IL18 IL1A IL1B IL1BC IL1BCE IL1F1 IL1F2 IL1F4 IRF1 IRF2 KET NEDF P53 P63 P73H P73L SHAX1 SHAX2 SHAX3 TP53 TP63 TP73L VPS20 VPS24
Release of apoptotic factors from the mitochondria	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Cytochrome c Diablo IAP-binding mitochondrial protein Gasdermin-D Gasdermin-E	O60443 P57764 P99999 Q07812 Q16611 Q9NR28	BAK BAK1 BAX BCL2L4 BCL2L7 CDN1 CYC CYCS DFNA5 DFNA5L DIABLO GSDMD GSDMDC1 GSDME ICERE1 SMAC
Transcriptional regulation by RUNX2	Apoptosis regulator BAX Bone morphogenetic protein 2 Core-binding factor subunit beta Cyclin-dependent kinase 1 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1 G1/S-specific cyclin-D1 G2/mitotic-specific cyclin-B1 Heart- and neural crest derivatives-expressed protein 2 Histone deacetylase 6 Protein phosphatase 1D Transcription factor SOX-9 Twist-related protein 1 Twist-related protein 2	O15297 P06493 P11802 P12643 P14635 P24385 P38936 P48436 P61296 Q07812 Q13951 Q15672 Q8WVJ9 Q9UBN7	BAX BCL1 BCL2L4 BHLHA26 BHLHA38 BHLHA39 BMP2 BMP2A CAP20 CBFB CCNB CCNB1 CCND1 CDC2 CDC28A CDK1 CDK4 CDKN1 CDKN1A CIP1 DERMO1 DHAND HAND2 HDAC6 KIAA0901 MDA6 P34CDC2 PIC1 PPM1D PRAD1 SDI1 SOX9 TWIST TWIST1 TWIST2 WAF1 WIP1
NTRK3 as a dependence receptor	Apoptosis regulator BAX NT-3 growth factor receptor Negative elongation factor B	Q07812 Q16288 Q8WX92	BAX BCL2L4 COBRA1 KIAA1182 NELFB NTRK3 TRKC
Estrogen-dependent gene expression	Apoptosis regulator Bcl-2 Axin-1 BTB/POZ domain-containing protein KCTD6 CREB-binding protein CXXC-type zinc finger protein 5 Cathepsin D Cbp/p300-interacting transactivator 1 Chromodomain-helicase-DNA-binding protein 1 Cohesin subunit SA-1 Cohesin subunit SA-2 Core-binding factor subunit beta Cyclic AMP-dependent transcription factor ATF-2 Cyclin-T1 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Double-strand-break repair protein rad21 homolog Estrogen receptor G1/S-specific cyclin-D1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Glycerol-3-phosphate acyltransferase 1, mitochondrial Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Helicase MOV-10 Hepatocyte nuclear factor 3-alpha Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2B Histone acetyltransferase KAT5 Histone acetyltransferase p300 Histone deacetylase 1 Histone-arginine methyltransferase CARM1 Importin subunit alpha-1 KN motif and ankyrin repeat domain-containing protein 1 Lysine-specific demethylase 4B Lysine-specific histone demethylase 1A Mediator of RNA polymerase II transcription subunit 1 Myc proto-oncogene protein Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 3 Nuclear receptor subfamily 5 group A member 2 Nuclear receptor-interacting protein 1 POU domain, class 2, transcription factor 1 Peptidyl-prolyl cis-trans isomerase FKBP4 Probable ATP-dependent RNA helicase DDX5 Progesterone receptor Prostaglandin E synthase 3 Protein FosB Protein GREB1 Protein arginine N-methyltransferase 1 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Protein c-Fos Protransforming growth factor alpha Receptor-binding cancer antigen expressed on SiSo cells Runt-related transcription factor 1 Stromal cell-derived factor 1 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 TATA-box-binding protein Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor Jun Transcription factor JunD Transcription factor Sp1 Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcriptional activator Myb Transcriptional repressor protein YY1 Transducin-like enhancer protein 3 Trefoil factor 1 Trefoil factor 3 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Upstream stimulatory factor 1 Upstream stimulatory factor 2 Zinc finger protein 217	O00482 O00559 O14646 O15169 O15514 O60216 O60341 O60563 O60814 O75362 O94953 P01100 P01106 P01135 P03372 P04155 P04908 P05412 P06401 P06899 P07339 P07900 P08047 P08238 P0C5Y9 P10242 P10415 P13984 P14859 P15336 P16104 P17535 P17844 P19387 P19388 P20226 P20671 P22415 P23527 P23771 P24385 P24928 P25490 P30876 P33778 P35269 P36954 P48061 P48552 P50750 P52292 P52434 P52435 P52655 P52657 P53539 P53803 P55317 P57053 P58876 P61218 P62487 P62805 P62807 P62875 P68431 P84243 Q01196 Q02790 Q04726 Q07654 Q09472 Q13547 Q13951 Q14678 Q14683 Q15185 Q15596 Q15648 Q15788 Q15853 Q16777 Q16778 Q4ZG55 Q6FI13 Q71DI3 Q71UI9 Q7LFL8 Q86X55 Q8N257 Q8N3U4 Q8NC69 Q8NDV7 Q8WVM7 Q92793 Q92831 Q92993 Q93077 Q93079 Q96A08 Q99873 Q99877 Q99878 Q99879 Q99880 Q99966 Q9BTM1 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9HCL2 Q9UKV8 Q9UL18 Q9UPQ9 Q9UQE7 Q9Y6Q9	AGO1 AGO2 AGO3 AGO4 AIB1 AML1 ANKRD15 AOF2 ARC205 ATF2 AXIN AXIN1 B1F BAM BCEI BCL1 BCL2 BHLHB11 BHLHB12 BHLHE39 BHLHE42 BHLHE74 BHLHE75 BMH CAGH26 CARM1 CBFA2 CBFB CBP CCND1 CCNT1 CDC2L4 CDK9 CHD1 CITED1 CPF CPSD CREB2 CREBBP CREBP1 CRSP1 CRSP200 CSPG6 CTSD CXCL12 CXXC5 DDX5 DRIP205 DRIP230 DXS423E EBAG9 EIF2C1 EIF2C2 EIF2C3 EIF2C4 EP300 ESR ESR1 FKBP4 FKBP52 FOS FOSB FOXA1 FTF G0S3 G0S7 G17P1 GATA3 GPAM GPAT1 GREB1 GTF2A1 GTF2A2 GTF2D1 GTF2F1 GTF2F2 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HDAC1 HELR HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HLR1 HMT2 HNF3A HR21 HRMT1L2 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB HTATIP INO80S IR1B4 ITF JHDM3B JMJD2B JUN JUND KANK KANK1 KAT2B KAT5 KCTD6 KDM1 KDM1A KDM4B KIAA0078 KIAA0172 KIAA0178 KIAA0575 KIAA0601 KIAA0876 KIAA1093 KIAA1460 KIAA1547 KIAA1560 KIAA1567 KIAA1582 KIAA1631 KPNA2 LSD1 MED1 MOV10 MSG1 MYB MYC NCOA1 NCOA2 NCOA3 NR3A1 NR3C3 NR5A2 NRIP1 NXP1 OCT1 OTF1 P23 P300 PBP PCAF PGR POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF POU2F1 PPARBP PPARGBP PRAD1 PRMT1 PRMT4 PS2 PTGES3 RAC3 RAD21 RAP30 RAP74 RB18A RCAS1 RCH1 RPB7 RPD3L1 RUNX1 SA1 SA2 SB1.8 SCC1 SCC3 SDF1 SDF1A SDF1B SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SP1 SRC1 SRC2 SRP1 STAG1 STAG2 TAK TBP TCF3A TEBP TF2A1 TF2A2 TF2D TFF1 TFF3 TFI TFIID TGFA TIF2 TIP60 TLE3 TNRC6 TNRC6A TNRC6B TNRC6C TRAM1 TRAP220 TRIP2 TSFP1 TSH2B USF USF1 USF2 YY1 ZABC1 ZNF217
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	Apoptosis regulator Bcl-2 BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 Bcl-2-like protein 11 Bcl-2-like protein 1 Bcl-2-modifying factor Bcl2-associated agonist of cell death Phorbol-12-myristate-13-acetate-induced protein 1 Signal transducer and activator of transcription 3	O43521 P10415 P40763 P55957 Q07817 Q13794 Q92934 Q96LC9 Q9BXH1	APRF BAD BBC3 BBC6 BCL2 BCL2L BCL2L1 BCL2L11 BCL2L8 BCLX BID BIM BMF NOXA PMAIP1 PUMA STAT3
CLEC7A/inflammasome pathway	Apoptosis-associated speck-like protein containing a CARD Caspase-8 Interleukin-1 beta Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	P01584 P19838 Q04206 Q14790 Q9UDY8 Q9ULZ3	ASC CARD5 CASP8 IL1B IL1F2 MALT1 MCH5 MLT NFKB1 NFKB3 PYCARD RELA TMS1
Activation of PUMA and translocation to mitochondria	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Bcl-2-binding component 3, isoforms 1/2 Cellular tumor antigen p53 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Tumor protein 63 Tumor protein p73	O15350 P04637 Q01094 Q13625 Q14186 Q14188 Q96KQ4 Q9BXH1 Q9H3D4	ASPP1 ASPP2 BBC3 BBP DP1 DP2 E2F1 KET KIAA0771 P53 P63 P73 P73H P73L PPP1R13B PUMA RBBP3 TFDP1 TFDP2 TP53 TP53BP2 TP63 TP73 TP73L
TP53 Regulates Transcription of Death Receptors and Ligands	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10C Tumor necrosis factor receptor superfamily member 10D Tumor necrosis factor receptor superfamily member 6 Tumor protein 63 Tumor protein p73	O00220 O14763 O14798 O15350 P04637 P17936 P25445 Q13625 Q86XT9 Q96KQ4 Q9H3D4 Q9UBN6	APO2 APT1 ASPP1 ASPP2 BBP DCR1 DCR2 DR4 DR5 FAS FAS1 IBP3 IGFBP3 KET KIAA0771 KILLER LIT P53 P63 P73 P73H P73L PPP1R13B TMEM219 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF6 TP53 TP53BP2 TP63 TP73 TP73L TRAILR1 TRAILR2 TRAILR3 TRAILR4 TRICK2 TRID TRUNDD ZTNFR9
Regulation of TP53 Activity through Association with Co-factors	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 PHD finger protein 20 POU domain, class 4, transcription factor 1 POU domain, class 4, transcription factor 2 Protein BANP RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase RelA-associated inhibitor Tumor protein 63 Tumor protein p73 Zinc finger protein 385A	O15350 P04637 P31749 P31751 Q01851 Q12837 Q13625 Q8N9N5 Q8WUF5 Q96KQ4 Q96PM9 Q9BVI0 Q9H3D4 Q9Y243	AKT1 AKT2 AKT3 ASPP1 ASPP2 BANP BBP BEND1 BRN3A BRN3B C20orf104 GLEA2 HCA58 HZF IASPP KET KIAA0771 NKIP1 NZF P53 P63 P73 P73H P73L PHF20 PKB PKBG POU4F1 POU4F2 PPP1R13B PPP1R13BL PPP1R13L RAC RAI RDC1 RZF SMAR1 TP53 TP53BP2 TP63 TP73 TP73L TZP ZNF385 ZNF385A
Transcriptional Regulation by E2F6	Apoptotic protease-activating factor 1 Breast cancer type 1 susceptibility protein Cell division cycle 7-related protein kinase Chromobox protein homolog 3 Chromobox protein homolog 5 DNA endonuclease RBBP8 DNA repair protein RAD51 homolog 1 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Enhancer of polycomb homolog 1 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Histone-lysine N-methyltransferase EZH2 Lethal(3)malignant brain tumor-like protein 2 MAX gene-associated protein Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polycomb group RING finger protein 6 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 3 Protein UXT Protein max RING1 and YY1-binding protein Ribonucleoside-diphosphate reductase subunit M2 Serine/threonine-protein kinase Chk1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F6 YY1-associated factor 2	O00311 O14727 O14757 O75461 O75530 P31350 P35226 P35227 P38398 P45973 P61244 P78364 Q01094 Q06587 Q06609 Q09028 Q13185 Q14186 Q14188 Q15022 Q15910 Q16576 Q8IWI9 Q8IY57 Q8N488 Q8NDX5 Q969R5 Q96KQ7 Q99496 Q99708 Q9BYE7 Q9H2F5 Q9H9B1 Q9UBK9	APAF1 BAP1 BAT8 BHLHD4 BMI1 BRCA1 C6orf30 CBX3 CBX5 CDC7 CDC7L1 CHEK1 CHET9 CHK1 CTIP DEDAF DING DP1 DP2 E2F1 E2F6 EDR1 EDR3 EED EHMT1 EHMT2 EPC1 EUHMTASE1 EZH2 G9A GLP HIPI3 HP1A JJAZ1 KIAA0160 KIAA0413 KIAA0518 KIAA1876 KMT1C KMT1D KMT6 L3MBTL2 MAD5 MAX MBLR MEL18 MGA NG36 PCGF2 PCGF4 PCGF6 PH1 PH3 PHC1 PHC3 RAD51 RAD51A RBAP46 RBAP48 RBBP3 RBBP4 RBBP7 RBBP8 RECA RING1 RING1A RING1B RNF1 RNF110 RNF134 RNF2 RNF51 RNF53 RR2 RRM2 RYBP SUZ12 TFDP1 TFDP2 UXT YAF2 YEAF1 ZNF144
Regulation of the apoptosome activity	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP Methylthioribulose-1-phosphate dehydratase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Uveal autoantigen with coiled-coil domains and ankyrin repeats	O14727 P27361 P28482 P55211 P98170 P99999 Q96GX9 Q9BZF9 Q9NQS1 Q9NR28 Q9Y2G2	APAF1 API3 APIP AVEN BIRC4 CARD8 CASP9 CYC CYCS DACAR DIABLO ERK1 ERK2 IAP3 KIAA0413 KIAA0955 KIAA1561 MAPK1 MAPK3 MCH6 NDPP1 PRKM1 PRKM2 PRKM3 SMAC UACA XIAP
Formation of apoptosome	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Methylthioribulose-1-phosphate dehydratase	O14727 P55211 P99999 Q96GX9 Q9NQS1 Q9Y2G2	APAF1 APIP AVEN CARD8 CASP9 CYC CYCS DACAR KIAA0413 KIAA0955 MCH6 NDPP1
TP53 Regulates Transcription of Caspase Activators and Caspases	Apoptotic protease-activating factor 1 Caspase-10 Caspase-1 Caspase-2 Caspase-6 Cellular tumor antigen p53 Death domain-containing protein CRADD NLR family CARD domain-containing protein 4 Serine-protein kinase ATM Tumor protein 63 Tumor protein p73 p53-induced death domain-containing protein 1	O14727 O15350 P04637 P29466 P42575 P55212 P78560 Q13315 Q92851 Q9H3D4 Q9HB75 Q9NPP4	APAF1 ATM CARD12 CASP1 CASP10 CASP2 CASP6 CLAN CLAN1 CRADD ICH1 IL1BC IL1BCE IPAF KET KIAA0413 LRDD MCH2 MCH4 NEDD2 NLRC4 P53 P63 P73 P73H P73L PIDD PIDD1 RAIDD TP53 TP63 TP73 TP73L
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP
SMAC (DIABLO) binds to IAPs	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP
Activation of caspases through apoptosome-mediated cleavage	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS IAP3 KIAA0413 MCH3 MCH6 XIAP

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