GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1501 - 1525** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Lectin pathway of complement activation	Collectin-10 Collectin-11 Ficolin-1 Ficolin-2 Ficolin-3 Mannan-binding lectin serine protease 1 Mannose-binding protein C	O00602 O75636 P11226 P48740 Q15485 Q9BWP8 Q9Y6Z7	CLL1 COLEC1 COLEC10 COLEC11 CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 MASP1 MBL MBL2 PRSS5	G49108TO G57321FI
Signaling by CSF3 (G-CSF)	GRB2-associated-binding protein 2 GTPase KRas Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Growth factor receptor-bound protein 2 Non-receptor tyrosine-protein kinase TYK2 SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11	O14543 O15524 O60674 P01116 P07948 P08631 P09919 P23458 P29353 P29597 P40763 P42224 P42229 P43405 P51692 P62993 Q06124 Q99062 Q9UQC2	APRF ASH C17orf33 CIS3 CSF3 CSF3R GAB2 GCSF GCSFR GRB2 HCK JAK1 JAK1A JAK1B JAK2 JTK8 KIAA0571 KRAS KRAS2 LYN PTP2C PTPN11 RASK2 SHC SHC1 SHCA SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TIP3 TYK2
NOTCH4 Intracellular Domain Regulates Transcription	Actin, aortic smooth muscle CREB-binding protein Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Mothers against decapentaplegic homolog 3 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 4 Recombining binding protein suppressor of hairless SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Vascular endothelial growth factor receptor 3	P35916 P46531 P62736 P84022 Q04721 Q06330 Q09472 Q13495 Q13573 Q14469 Q5TA89 Q8IZL2 Q92585 Q92793 Q92830 Q92831 Q96JK9 Q99466 Q9UBP5 Q9Y5J3	ACTA2 ACTSA ACTVS BHLHB31 BHLHB32 BHLHB38 BHLHB39 CBP CG1 CHF1 CHF2 CREBBP CXorf6 EP300 FLT4 GCN5 GCN5L2 GRL HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HL HRT1 HRT2 HRY IGKJRB IGKJRB1 INT3 KAT2A KAT2B KIAA0200 KIAA1816 KIAA1819 MADH3 MAML1 MAML2 MAML3 MAMLD1 NOTCH1 NOTCH2 NOTCH4 P300 PCAF RBPJ RBPJK RBPSUH SKIIP SKIP SMAD3 SNW1 TAN1 VEGFR3
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 TATA-binding protein-associated factor 2N TATA-box-binding protein Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B	O00268 O15514 P13984 P18074 P19387 P19388 P19447 P20226 P21675 P24928 P29083 P29084 P30876 P32780 P35269 P36954 P49848 P50613 P51946 P51948 P52434 P52435 P52655 P52657 P53803 P61218 P62487 P62875 Q00403 Q12962 Q13888 Q13889 Q15542 Q15543 Q15544 Q15545 Q16514 Q16594 Q5H9L4 Q5VWG9 Q6P1X5 Q6ZYL4 Q8IZX4 Q92750 Q92759 Q92804 Q9HBM6	BA2R BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCG1 CCGS CCNH CDK7 CDKN7 CIF150 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2D1 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MAT1 MNAT1 MO15 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RBP56 RNF66 RPB7 STK1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TBP TF2A1 TF2A2 TF2B TF2D TF2E1 TF2E2 TFIIB TFIID TTDA XPB XPBC XPD XPDC
Vasopressin regulates renal water homeostasis via Aquaporins	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rab11 family-interacting protein 2 Ras-related protein Rab-11A Unconventional myosin-Vb Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14610 O14775 O43306 O60262 O60266 O60503 O95622 P01185 P10644 P13861 P16520 P17612 P22612 P22694 P29972 P30518 P31321 P31323 P40145 P41181 P50150 P50151 P51828 P55087 P59768 P61952 P62491 P62873 P62879 P63092 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q7L804 Q8NFM4 Q92482 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08 Q9ULV0	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADHR AQP1 AQP2 AQP3 AQP4 ARVP AVP AVPR2 CHIP28 DIR DIR3 GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0941 KIAA1060 KIAA1119 MYO5B PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B RAB11 RAB11A RAB11FIP2 TSE1 V2R VP
Defective VWF cleavage by ADAMTS13 variant	A disintegrin and metalloproteinase with thrombospondin motifs 13 von Willebrand factor	P04275 Q76LX8	ADAMTS13 C9orf8 F8VWF VWF
Defective pro-SFTPB causes SMDP1 and RDS	Pulmonary surfactant-associated protein B	P07988	SFTP3 SFTPB
Maturation of protein 3a	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ORF3a protein Polypeptide N-acetylgalactosaminyltransferase 1	P15907 P59632 Q10472 Q11201 Q11203 Q11206 Q16842 Q8NDV1 Q9H4F1 Q9UJ37	3a CGS23 GALNT1 NANTA3 SIAT1 SIAT3C SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SIAT7B SIAT7C SIAT7D SIATL1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST6GAL1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 STHM STZ
Synthesis of PS	Phosphatidylserine synthase 1 Phosphatidylserine synthase 2	P48651 Q9BVG9	KIAA0024 PSS2 PSSA PTDSS1 PTDSS2
Synthesis of PIPs at the ER membrane	Myotubularin-related protein 2 Myotubularin-related protein 5 Phosphatidylinositol 4-kinase alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol-3-phosphatase SAC1	O95248 P42356 Q13614 Q8TCG2 Q9NTJ5	KIAA0851 KIAA1073 MTMR2 MTMR5 PI4K2B PI4KA PIK4 PIK4CA SAC1 SACM1L SBF1
NS1 Mediated Effects on Host Pathways	Aladin E3 SUMO-protein ligase RanBP2 Importin subunit alpha-1 Importin subunit alpha-3 Importin subunit alpha-4 Importin subunit alpha-5 Importin subunit alpha-6 Importin subunit alpha-8 Importin subunit beta-1 Non-structural protein 1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog Ubiquitin-like protein ISG15 mRNA export factor RAE1	A8CG34 A9QM74 O00505 O00629 O15131 O15504 O75694 P03496 P05161 P12270 P35658 P37198 P49790 P49792 P52292 P52294 P55735 P57740 P78406 Q12769 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E G1P2 ISG15 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA7 KPNB1 MP44 MRNP41 NDC1 NPAP60L NS NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C QIP1 QIP2 RAE1 RANBP2 RCH1 RCH2 SEC13 SEC13A SEC13L1 SEC13R SRP1 TMEM48 TPR UCRP
FGFR3c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Polypeptide N-acetylgalactosaminyltransferase 3	O43320 O76093 P05230 P08620 P09038 P31371 Q14435 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB GALNT3 HST HSTF1 HYPF KS3
Initial triggering of complement	Collectin-10 Collectin-11 Complement C1q subcomponent subunit A Complement C1q subcomponent subunit B Complement C1q subcomponent subunit C Complement C1r subcomponent Complement C1s subcomponent Complement C2 Complement C4-A Complement C4-B Ficolin-1 Ficolin-2 Ficolin-3 IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Mannan-binding lectin serine protease 1 Mannose-binding protein C UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O00602 O75636 P00736 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P02745 P02746 P02747 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P06681 P09871 P0C0L4 P0C0L5 P0CF74 P0CG04 P0DOY2 P0DOY3 P11226 P23083 P48740 P80748 Q15485 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9BWP8 Q9Y6Z7	C1QA C1QB C1QC C1QG C1R C1S C2 C4A C4B C4B_2 CLL1 CO4 COLEC1 COLEC10 COLEC11 CPAMD2 CPAMD3 CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 MASP1 MBL MBL2 PRSS5 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6	G49108TO G57321FI
RA biosynthesis pathway	2-aminomuconic semialdehyde dehydrogenase Alcohol dehydrogenase 1A Alcohol dehydrogenase 1C Aldehyde dehydrogenase 1A1 Aldo-keto reductase family 1 member C3 All-trans-retinol dehydrogenase [NAD(+)] ADH4 Cellular retinoic acid-binding protein 1 Cytochrome P450 26A1 Cytochrome P450 26B1 Cytochrome P450 26C1 Dehydrogenase/reductase SDR family member 4 Dehydrogenase/reductase SDR family member 9 Epidermal retinol dehydrogenase 2 Retinal dehydrogenase 2 Retinaldehyde dehydrogenase 3 Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 13 Retinol dehydrogenase 14 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Short-chain dehydrogenase/reductase 3	O43174 O75452 O75911 O94788 P00326 P00352 P07327 P08319 P29762 P42330 P47895 Q6V0L0 Q8IZV5 Q8N3Y7 Q8NBN7 Q8TC12 Q92781 Q9BPW9 Q9BTZ2 Q9H2A2 Q9HBH5 Q9NR63	ADH1 ADH1A ADH1C ADH2 ADH3 ADH4 AKR1C3 ALDC ALDH1 ALDH12 ALDH1A1 ALDH1A2 ALDH1A3 ALDH6 ALDH8A1 ARSDR1 CRABP1 CYP26 CYP26A1 CYP26A2 CYP26B1 CYP26C1 DDH1 DHRS3 DHRS4 DHRS9 HSD17B5 HSD17B9 KIAA0119 P450RAI1 P450RAI2 PAN2 PGFS PSDR1 PUMB1 RALDH2 RBP5 RDH1 RDH10 RDH11 RDH13 RDH14 RDH15 RDH16 RDH17 RDH5 RDHE2 RODH4 SDR16C1 SDR16C4 SDR16C5 SDR25C2 SDR7C1 SDR7C3 SDR7C4 SDR9C4 SDR9C5 SDR9C8
Regulation of BACH1 activity	Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/LRR-repeat protein 17 Polyubiquitin-B Polyubiquitin-C S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Transcription factor MafK Transcription regulator protein BACH1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14867 O60675 P0CG47 P0CG48 P62877 P62979 P62987 P63208 Q13309 Q13616 Q9UF56	BACH1 CUL1 EMC19 FBL17 FBX13 FBXL1 FBXL17 FBXO13 MAFK OCP2 RBX1 RNF75 ROC1 RPS27A SKP1 SKP1A SKP2 TCEB1L UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Zinc efflux and compartmentalization by the SLC30 family	Probable proton-coupled zinc antiporter SLC30A3 Proton-coupled zinc antiporter SLC30A1 Proton-coupled zinc antiporter SLC30A2 Proton-coupled zinc antiporter SLC30A5 Proton-coupled zinc antiporter SLC30A8	Q8IWU4 Q8TAD4 Q99726 Q9BRI3 Q9Y6M5	SLC30A1 SLC30A2 SLC30A3 SLC30A5 SLC30A8 ZNT1 ZNT2 ZNT3 ZNT5 ZNT8 ZNTL1 ZTL1
TLR3-mediated TICAM1-dependent programmed cell death	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 Toll-like receptor 3	O15455 Q13158 Q13546 Q14790 Q8IUC6 Q9Y572	CASP8 FADD MCH5 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TLR3 TRIF
Interconversion of nucleotide di- and triphosphates	Adenylate kinase 2, mitochondrial Adenylate kinase 4, mitochondrial Adenylate kinase 7 Adenylate kinase 8 Adenylate kinase 9 Adenylate kinase isoenzyme 1 Adenylate kinase isoenzyme 5 Adenylate kinase isoenzyme 6 CTP synthase 1 CTP synthase 2 Deoxycytidylate deaminase Glutaredoxin-1 Guanylate kinase NAD(P)H pyrophosphatase NUDT13, mitochondrial Nucleoside diphosphate kinase 3 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleoside diphosphate kinase, mitochondrial Putative nucleoside diphosphate kinase Ribonucleoside-diphosphate reductase large subunit Ribonucleoside-diphosphate reductase subunit M2 B Ribonucleoside-diphosphate reductase subunit M2 Thioredoxin reductase 1, cytoplasmic Thioredoxin Thymidylate kinase Thymidylate synthase UMP-CMP kinase dCTP pyrophosphatase 1	O00746 O60361 P00568 P04818 P10599 P15531 P17812 P22392 P23919 P23921 P27144 P30085 P31350 P32321 P35754 P54819 Q13232 Q16774 Q16881 Q5TCS8 Q7LG56 Q86X67 Q96M32 Q96MA6 Q9H773 Q9NRF8 Q9Y3D8 Q9Y6K8	ADK2 AK1 AK2 AK3 AK3L1 AK4 AK5 AK6 AK7 AK8 AK9 AKD1 AKD2 C6orf199 C6orf224 C9orf98 CDC8 CINAP CMK CMPK CMPK1 CTPS CTPS1 CTPS2 DCTD DCTPP1 DTYMK GLRX GMK GMPK GRIM12 GRX GUK1 KDRF NDPKA NM23 NM23B NM23D NME1 NME2 NME2P1 NME3 NME4 NUDT13 P53R2 RR1 RR2 RRM1 RRM2 RRM2B TMPK TRDX TRX TRX1 TS TXN TXNRD1 TYMK TYMS UCK UMK UMPK XTP3TPA
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	14-3-3 protein sigma Apoptosis regulator BAX Aurora kinase A Cellular tumor antigen p53 Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Growth arrest and DNA damage-inducible protein GADD45 alpha Histone acetyltransferase p300 Histone-arginine methyltransferase CARM1 M-phase inducer phosphatase 3 Proliferating cell nuclear antigen Protein arginine N-methyltransferase 1 Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Zinc finger protein 385A	O14965 P04637 P06493 P12004 P14635 P24522 P28749 P30307 P31947 Q07812 Q08999 Q09472 Q14186 Q14188 Q16254 Q86X55 Q96PM9 Q99873	AIK AIRK1 ARK1 AURA AURKA AYK1 BAX BCL2L4 BTAK CARM1 CCNB CCNB1 CDC2 CDC25C CDC28A CDK1 CDKN1 DDIT1 DP1 DP2 E2F4 EP300 GADD45 GADD45A HME1 HMT2 HRMT1L2 HZF IAK1 IR1B4 P300 P34CDC2 P53 PCNA PRMT1 PRMT4 RB2 RBL1 RBL2 RZF SFN STK15 STK6 TFDP1 TFDP2 TP53 ZNF385 ZNF385A
LDL clearance	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Apolipoprotein B-100 Carboxylesterase 3 Clathrin heavy chain 1 Clathrin light chain A Lipolysis-stimulated lipoprotein receptor Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor Lysosomal acid lipase/cholesteryl ester hydrolase NPC intracellular cholesterol transporter 1 NPC intracellular cholesterol transporter 2 Neutral cholesterol ester hydrolase 1 Proprotein convertase subtilisin/kexin type 9 Sterol O-acyltransferase 1 Sterol O-acyltransferase 2	O15118 O75908 O94973 O95782 P01130 P04114 P09496 P35610 P38571 P53680 P61916 P63010 Q00610 Q5SW96 Q6PIU2 Q6UWW8 Q86X29 Q8NBP7 Q96CW1	AADACL1 ACACT ACACT1 ACACT2 ACAT ACAT1 ACAT2 ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARH CES3 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 HE1 HIP9 HYPJ ILDR3 KIAA0034 KIAA0109 KIAA0899 KIAA1363 LDLR LDLRAP1 LIPA LISCH LSR NARC1 NCEH1 NPC1 NPC2 PCSK9 SOAT SOAT1 SOAT2 STAT
Regulation of FOXO transcriptional activity by acetylation	CREB-binding protein Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Histone acetyltransferase KAT2B Histone acetyltransferase p300 NAD-dependent protein deacetylase sirtuin-1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Thioredoxin-interacting protein Thioredoxin	O43524 P10599 P98177 Q09472 Q12778 Q92793 Q92831 Q96EB6 Q9H3M7 Q9NTG7	AFX AFX1 CBP CREBBP EP300 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 KAT2B MLLT7 P300 PCAF SIR2L1 SIR2L3 SIRT1 SIRT3 TRDX TRX TRX1 TXN TXNIP VDUP1
Integration of energy metabolism	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	P30153 P30154 P62714 P67775 Q14738	PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D
Nef Mediated CD4 Down-regulation	ADP-ribosylation factor 1 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Protein Nef T-cell surface glycoprotein CD4 Tyrosine-protein kinase Lck V-type proton ATPase subunit H	O94973 O95782 P01730 P04601 P06239 P53680 P63010 P84077 Q96CW1 Q9UI12	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 ATP6V1H CD4 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 HIP9 HYPJ KIAA0109 KIAA0899 LCK nef
RUNX1 regulates expression of components of tight junctions	Claudin-5 Core-binding factor subunit beta Occludin Runt-related transcription factor 1 Tight junction protein ZO-1	O00501 Q01196 Q07157 Q13951 Q16625	AML1 AWAL CBFA2 CBFB CLDN5 OCLN RUNX1 TJP1 TMVCF ZO1
Neurotransmitter clearance	Acetylcholinesterase Cholinesterase Solute carrier family 22 member 1 Solute carrier family 22 member 2	O15244 O15245 P06276 P22303	ACHE BCHE CHE1 OCT1 OCT2 SLC22A1 SLC22A2

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