GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **2026 - 2050** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	O14610 O14775 O60262 O75899 P16520 P48050 P48051 P48544 P48549 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P63252 P78508 Q14500 Q92806 Q99712 Q9HAV0 Q9NPI9 Q9P2W3 Q9UBI6 Q9UBS5 Q9UK08	GABBR1 GABBR2 GIRK1 GIRK2 GIRK3 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPR51 GPRC3A GPRC3B IRK1 IRK2 IRK3 KATP2 KCNJ10 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ7 KCNJ9 KCNJN1
Mitochondrial translation initiation	Alpha-ketoglutarate dehydrogenase component 4 GTPase Era, mitochondrial Large ribosomal subunit protein bL12m Large ribosomal subunit protein bL17m Large ribosomal subunit protein bL19m Large ribosomal subunit protein bL20m Large ribosomal subunit protein bL21m Large ribosomal subunit protein bL27m Large ribosomal subunit protein bL28m Large ribosomal subunit protein bL32m Large ribosomal subunit protein bL33m Large ribosomal subunit protein bL34m Large ribosomal subunit protein bL35m Large ribosomal subunit protein bL36m Large ribosomal subunit protein bL9m Large ribosomal subunit protein mL37 Large ribosomal subunit protein mL38 Large ribosomal subunit protein mL39 Large ribosomal subunit protein mL40 Large ribosomal subunit protein mL41 Large ribosomal subunit protein mL42 Large ribosomal subunit protein mL43 Large ribosomal subunit protein mL44 Large ribosomal subunit protein mL45 Large ribosomal subunit protein mL46 Large ribosomal subunit protein mL48 Large ribosomal subunit protein mL49 Large ribosomal subunit protein mL50 Large ribosomal subunit protein mL51 Large ribosomal subunit protein mL52 Large ribosomal subunit protein mL53 Large ribosomal subunit protein mL54 Large ribosomal subunit protein mL55 Large ribosomal subunit protein mL62 Large ribosomal subunit protein mL63 Large ribosomal subunit protein mL64 Large ribosomal subunit protein mL65 Large ribosomal subunit protein mL66 Large ribosomal subunit protein uL10m Large ribosomal subunit protein uL11m Large ribosomal subunit protein uL13m Large ribosomal subunit protein uL14m Large ribosomal subunit protein uL15m Large ribosomal subunit protein uL16m Large ribosomal subunit protein uL18m Large ribosomal subunit protein uL1m Large ribosomal subunit protein uL22m Large ribosomal subunit protein uL23m Large ribosomal subunit protein uL24m Large ribosomal subunit protein uL29m Large ribosomal subunit protein uL2m Large ribosomal subunit protein uL30m Large ribosomal subunit protein uL3m Large ribosomal subunit protein uL4m Methionyl-tRNA formyltransferase, mitochondrial Mitochondrial inner membrane protein OXA1L Small ribosomal subunit protein bS16m Small ribosomal subunit protein bS18m Small ribosomal subunit protein bS1m Small ribosomal subunit protein bS21m Small ribosomal subunit protein bS6m Small ribosomal subunit protein mS22 Small ribosomal subunit protein mS23 Small ribosomal subunit protein mS25 Small ribosomal subunit protein mS26 Small ribosomal subunit protein mS27 Small ribosomal subunit protein mS29 Small ribosomal subunit protein mS31 Small ribosomal subunit protein mS33 Small ribosomal subunit protein mS34 Small ribosomal subunit protein mS35 Small ribosomal subunit protein mS37 Small ribosomal subunit protein mS38 Small ribosomal subunit protein mS39 Small ribosomal subunit protein mS40 Small ribosomal subunit protein uS10m Small ribosomal subunit protein uS11m Small ribosomal subunit protein uS12m Small ribosomal subunit protein uS14m Small ribosomal subunit protein uS15m Small ribosomal subunit protein uS17m Small ribosomal subunit protein uS2m Small ribosomal subunit protein uS3m Small ribosomal subunit protein uS5m Small ribosomal subunit protein uS7m Small ribosomal subunit protein uS9m Translation initiation factor IF-2, mitochondrial Translation initiation factor IF-3, mitochondrial	O15235 O60783 O75394 O75616 P09001 P46199 P49406 P51398 P52815 P82650 P82663 P82664 P82673 P82675 P82909 P82912 P82914 P82921 P82930 P82932 P82933 Q13084 Q13405 Q14197 Q15070 Q16540 Q4U2R6 Q5T653 Q6P161 Q6P1L8 Q7Z2W9 Q7Z7F7 Q7Z7H8 Q86TS9 Q8IXM3 Q8N5N7 Q8N983 Q8TAE8 Q8TCC3 Q92552 Q92665 Q96A35 Q96BP2 Q96DP5 Q96DV4 Q96EL2 Q96EL3 Q96EY7 Q96GC5 Q9BQ48 Q9BQC6 Q9BRJ2 Q9BYC8 Q9BYC9 Q9BYD1 Q9BYD2 Q9BYD3 Q9BYD6 Q9BYN8 Q9BZE1 Q9H0U6 Q9H2K0 Q9H2W6 Q9H9J2 Q9HD33 Q9NP92 Q9NQ50 Q9NRX2 Q9NVS2 Q9NWT8 Q9NWU5 Q9NX20 Q9NYK5 Q9NZE8 Q9P015 Q9P0J6 Q9P0M9 Q9Y291 Q9Y2Q9 Q9Y2R5 Q9Y2R9 Q9Y399 Q9Y3B7 Q9Y3D3 Q9Y3D5 Q9Y3D9 Q9Y676 Q9Y6G3	AIP AKIP AURKAIP1 BMRP BRIP1 C10orf34 C11orf4 C15orf4 C20orf193 C21orf101 C21orf92 C2orf1 C3orf5 C6orf14 CHCHD1 DAP3 DS1 ERAL1 FMT FMT1 GADD45GIP1 HERA ICT1 IMOGN38 KGD4 KIAA0104 KIAA0264 L23MRP LIECG2 LIP2 MAAT1 MRL3 MRP63 MRP64 MRPL1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL19 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL25 MRPL27 MRPL28 MRPL3 MRPL30 MRPL31 MRPL32 MRPL33 MRPL34 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL41 MRPL42 MRPL43 MRPL44 MRPL45 MRPL46 MRPL47 MRPL48 MRPL49 MRPL5 MRPL50 MRPL51 MRPL52 MRPL53 MRPL54 MRPL55 MRPL57 MRPL58 MRPL59 MRPL7 MRPL8 MRPL9 MRPS10 MRPS11 MRPS12 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS18C MRPS2 MRPS21 MRPS22 MRPS23 MRPS24 MRPS25 MRPS26 MRPS27 MRPS28 MRPS29 MRPS30 MRPS31 MRPS32 MRPS33 MRPS34 MRPS35 MRPS36 MRPS37 MRPS38 MRPS39 MRPS5 MRPS6 MRPS7 MRPS9 MTFMT MTIF2 MTIF3 NCM1 NLVCF NOF1 OXA1L PDCD9 PLINP1 PRG6 PTCD3 RPL23L RPML12 RPML2 RPML25 RPML27 RPML28 RPML3 RPML31 RPML32 RPML5 RPML8 RPMS11 RPMS12 RPMS13 RPMS15 RPMS16 RPMS17 RPMS21 RPMS22 RPMS25 RPMS6 RPMS9 RPSM12 URIM
Other interleukin signaling	Alpha-taxilin Caspase-3 Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Interferon lambda receptor 1 Interferon lambda-1 Interleukin-10 receptor subunit beta Interleukin-32 Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Myeloblastin Non-receptor tyrosine-protein kinase TYK2 Pro-interleukin-16 Receptor-type tyrosine-protein phosphatase zeta Synaptosomal-associated protein 25 Syndecan-1 Syntaxin-1A Syntaxin-3 Syntaxin-4 Syntaxin-binding protein 2 T-cell surface glycoprotein CD4 Tyrosine-protein kinase JAK1 Vesicle-associated membrane protein 2	P01730 P07333 P09603 P09919 P18827 P23458 P23471 P24001 P24158 P29597 P40222 P42574 P60880 P63027 Q08334 Q12846 Q13277 Q14005 Q15833 Q16623 Q6ZMJ4 Q8IU54 Q8IU57 Q99062	C16orf77 C17orf33 CASP3 CD4 CPP32 CRFB4 CSF1 CSF1R CSF3 CSF3R D21S58 D21S66 FMS GCSF GCSFR HTPZP2 IFNL1 IFNLR1 IL10RB IL16 IL28RA IL29 IL32 IL34 JAK1 JAK1A JAK1B LICR2 MBN NK4 PRTN3 PTPRZ PTPRZ1 PTPRZ2 PTPZ SDC SDC1 SNAP SNAP25 STX1 STX1A STX3 STX3A STX4 STX4A STXBP2 SYB2 TAIF TXLN TXLNA TYK2 UNC18B VAMP2 ZCYTO21
FRS-mediated FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43559 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1
G2/M DNA replication checkpoint	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Wee1-like protein kinase	O95067 P06493 P14635 P30291 Q99640	CCNB CCNB1 CCNB2 CDC2 CDC28A CDK1 CDKN1 MYT1 P34CDC2 PKMYT1 WEE1
Beta-oxidation of pristanoyl-CoA	Acyl-coenzyme A oxidase-like protein Acyl-coenzyme A thioesterase 8 Alpha-methylacyl-CoA racemase Carnitine O-acetyltransferase Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal carnitine O-octanoyltransferase Peroxisomal multifunctional enzyme type 2	O14734 O15254 P43155 P51659 Q99424 Q9NUZ1 Q9UHK6 Q9UKG9	ACOT8 ACOX2 ACOX3 ACOXL ACTEIII AMACR BRCOX CAT1 COT CRAT CROT EDH17B4 HSD17B4 PRCOX PTE1 SDR8C1
Constitutive Signaling by EGFRvIII	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 E3 ubiquitin-protein ligase CBL Epidermal growth factor receptor GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor SHC-transforming protein 1 Son of sevenless homolog 1	P00533 P01111 P01112 P01133 P07900 P19174 P22681 P27986 P29353 P42336 Q07889 Q13480 Q16543	CBL CBL2 CDC37 CDC37A EGF EGFR ERBB ERBB1 GAB1 GRB1 HER1 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA NRAS PIK3CA PIK3R1 PLC1 PLCG1 RNF55 SHC SHC1 SHCA SOS1
HDR through Homologous Recombination (HRR)	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase eta DNA polymerase kappa DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15315 O43502 O43542 O43543 O60934 O75771 P0CG47 P0CG48 P12004 P15927 P27694 P28340 P35244 P35249 P35250 P35251 P38398 P40937 P40938 P49005 P49959 P51530 P51587 P54132 P56282 P60896 P62979 P62987 Q06609 Q07864 Q13315 Q13472 Q14191 Q15054 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9UQ84 Q9Y253	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CHRAC17 CTIP DINB1 DNA2 DNA2L DPE2 DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0039 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PCNA PIR51 POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLH POLK RAD30 RAD30A RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WRN XPV XRCC2 XRCC3
Amino acids regulate mTORC1	Cytosolic arginine sensor for mTORC1 subunit 1 Cytosolic arginine sensor for mTORC1 subunit 2 Folliculin-interacting protein 1 Folliculin-interacting protein 2 Folliculin GATOR1 complex protein DEPDC5 GATOR1 complex protein NPRL2 GATOR1 complex protein NPRL3 GATOR2 complex protein MIOS GATOR2 complex protein WDR24 GATOR2 complex protein WDR59 GTP-binding protein Rheb KICSTOR complex protein ITFG2 KICSTOR complex protein SZT2 KICSTOR complex protein kaptin KICSTOR subunit 2 Neutral amino acid transporter 9 Nucleoporin SEH1 Protein SEC13 homolog Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR S-adenosylmethionine sensor upstream of mTORC1 SH3 domain-binding protein 4 Serine/threonine-protein kinase mTOR Sestrin-1 Sestrin-2 Target of rapamycin complex subunit LST8 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G 3 V-type proton ATPase subunit H V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2	A6NHX0 O15342 O43504 O75140 O75348 O95670 P15313 P21281 P21283 P27449 P36543 P38606 P42345 P55735 P58004 P61421 Q0VGL1 Q12980 Q13488 Q15382 Q16864 Q1RMZ1 Q5T011 Q5VZM2 Q6IAA8 Q6PJI9 Q7L523 Q8N122 Q8N8Y2 Q8NBW4 Q8NEY4 Q8NFG4 Q8NHE4 Q8TF40 Q8WTW4 Q8WTX7 Q969R8 Q96A05 Q96EE3 Q96LB4 Q96MD2 Q96S15 Q99437 Q9BVC4 Q9HB90 Q9NQL2 Q9NXC5 Q9P0V3 Q9P278 Q9UHA4 Q9UI12 Q9Y2Q5 Q9Y5K8 Q9Y664 Q9Y6P5	ATP6A1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6E1 ATP6E2 ATP6EL2 ATP6F ATP6G ATP6G1 ATP6G2 ATP6G3 ATP6H ATP6J ATP6L ATP6M ATP6N1C ATP6S14 ATP6V0A3 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V0E2L ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1EL2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATPL BHD BMT2 BOG25 C11orf59 C12orf66 C16orf21 C16orf35 C1orf84 C7orf32 C7orf59 C7orf60 CASTOR1 CASTOR2 CGTHBA D3S1231E DEPDC5 EHB10 FLCN FNIP1 FNIP2 FNIPL FRAP FRAP1 FRAP2 GATSL1 GATSL2 GATSL3 GBL HBXIP Hi95 ITFG2 KIAA0467 KIAA0645 KIAA1303 KIAA1450 KIAA1923 KIAA1961 KICS2 KPTN LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP2K1IP1 MAPBPIP MAPKSP1 MAPO1 MARE MIOS MLST8 MTOR NG38 NPRL2 NPRL3 PA26 PDRO RAFT1 RAPT1 RAPTOR RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SAMTOR SEC13 SEC13A SEC13L SEC13L1 SEC13R SEH1 SEH1L SESN1 SESN2 SEST1 SEST2 SH3BP4 SLC38A9 SZT2 TCIRG1 TTP TUSC4 URLC11 VATB VATC VATD VATF VPATPD VPP2 VPP3 WDR24 WDR59 XIP
Truncations of AMER1 destabilize the destruction complex	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O43187 O43318 P08571 P0CG47 P0CG48 P62979 P62987 Q15750 Q86XR7 Q8IUC6 Q8N5C8 Q9NYJ8 Q9Y4K3 Q9Y6Y9	CD14 ESOP1 IRAK2 KIAA0733 LY96 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MD2 PRVTIRB RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-3' exoribonuclease 1 Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 MAP kinase-activated protein kinase 2 Transportin-1 m7GpppN-mRNA hydrolase mRNA decay activator protein ZFP36 mRNA-decapping enzyme 1A	P26651 P31946 P49137 Q06265 Q13868 Q15024 Q5RKV6 Q8IU60 Q8IZH2 Q92973 Q96B26 Q9NPD3 Q9NPI6 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2	CML28 CSL4 DCP1A DCP2 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 G0S24 KIAA0116 KIAA1008 KPNB2 MAPKAPK2 MIP1 MTR3 NUDT20 NUP475 OIP2 PMSCL1 RNF162A RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SEP1 SKI6 SMIF TIS11A TNPO1 TRN TTP XRN1 YWHAB ZFP36
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2
Histamine receptors	Histamine H1 receptor Histamine H2 receptor Histamine H3 receptor Histamine H4 receptor	P25021 P35367 Q9H3N8 Q9Y5N1	GPCR105 GPCR97 HRH1 HRH2 HRH3 HRH4
Interleukin-21 signaling	Cytokine receptor common subunit gamma Interleukin-21 receptor Interleukin-21 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3	P23458 P31785 P40763 P42224 P42229 P51692 P52333 Q14765 Q9HBE4 Q9HBE5	APRF IL21 IL21R IL2RG JAK1 JAK1A JAK1B JAK3 NILR STAT1 STAT3 STAT4 STAT5 STAT5A STAT5B
Negative regulation of FGFR1 signaling	Anosmin-1 E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15520 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P11487 P22681 P23352 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	ADMLX ANOS1 CBL CBL2 ERK1 ERK2 FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 HST HST2 HSTF1 HSTF2 HYPF INT2 KAL KAL1 KALIG1 KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	DIS3-like exonuclease 2 Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic initiation factor 4A-III Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E Polyadenylate-binding protein 1 Polyadenylate-binding protein 2 Polyadenylate-binding protein-interacting protein 1 Terminal uridylyltransferase 4 Terminal uridylyltransferase 7	P06730 P11940 P23588 P38919 P60842 Q04637 Q14240 Q5TAX3 Q5VYS8 Q86U42 Q8IYB7 Q9H074	DDX2A DDX2B DDX48 DIS3L2 EIF4A EIF4A1 EIF4A2 EIF4A3 EIF4B EIF4E EIF4EL1 EIF4F EIF4G EIF4G1 EIF4GI FAM6A HS2 KIAA0111 KIAA0191 KIAA1711 PAB1 PAB2 PABP PABP1 PABP2 PABPC1 PABPC2 PABPN1 PAIP1 TUT4 TUT7 ZCCHC11 ZCCHC6
RHO GTPases Activate WASPs and WAVEs	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Focal adhesion kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A6NGB9 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P16333 P27361 P28482 P42768 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 Q05397 Q06187 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92558 Q92747 Q96F07 Q9NYB9 Q9NZQ3 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CDC42 CR16 CYFIP1 CYFIP2 ERK1 ERK2 FAK FAK1 HEM1 HEM2 IMD2 JTK7 KIAA0068 KIAA0269 KIAA0587 KIAA0900 KIAA1168 MAPK1 MAPK3 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SOP2L SPIN90 SSH3BP1 TC25 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE
Fanconi Anemia Pathway	5' exonuclease Apollo ATR-interacting protein Centromere protein S Centromere protein X Crossover junction endonuclease EME1 Crossover junction endonuclease MUS81 DNA cross-link repair 1A protein DNA excision repair protein ERCC-1 DNA polymerase nu DNA repair endonuclease XPF E3 ubiquitin-protein ligase FANCL Fanconi anemia core complex-associated protein 100 Fanconi anemia core complex-associated protein 20 Fanconi anemia core complex-associated protein 24 Fanconi anemia group A protein Fanconi anemia group B protein Fanconi anemia group C protein Fanconi anemia group D2 protein Fanconi anemia group E protein Fanconi anemia group F protein Fanconi anemia group G protein Fanconi anemia group I protein Fanconi anemia group M protein Fanconi-associated nuclease 1 Polyubiquitin-B Polyubiquitin-C Probable crossover junction endonuclease EME2 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine/threonine-protein kinase ATR Structure-specific endonuclease subunit SLX1 Structure-specific endonuclease subunit SLX4 Ubiquitin carboxyl-terminal hydrolase 1 Ubiquitin-conjugating enzyme E2 T Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 48	A4GXA9 A8MT69 O15287 O15360 O94782 P07992 P0CG47 P0CG48 P15927 P27694 P35244 P62979 P62987 Q00597 Q0VG06 Q13535 Q6NZ36 Q6PJP8 Q7Z5Q5 Q8IY92 Q8IYD8 Q8N2Z9 Q8NB91 Q8TAF3 Q8WXE1 Q92889 Q96AY2 Q96NY9 Q9BQ83 Q9BTP7 Q9BXW9 Q9H816 Q9HB96 Q9NPD8 Q9NPI8 Q9NVI1 Q9NW38 Q9Y2M0	AGS1 APITD1 ATR ATRIP BTBD12 C17orf70 C19orf40 C1orf86 CENPS CENPX DCLRE1A DCLRE1B EME1 EME2 ERCC1 ERCC11 ERCC4 FAA FAAP10 FAAP100 FAAP16 FAAP20 FAAP24 FAC FACA FACC FACD FACE FAN1 FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCH FANCI FANCL FANCM FRP1 GIYD1 GIYD2 KIAA0086 KIAA1018 KIAA1449 KIAA1596 KIAA1784 KIAA1794 KIAA1987 MHF1 MHF2 MMS4 MTMR15 MUS81 PHF9 POLN REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPS27A SLX1 SLX1A SLX1B SLX4 SNM1 SNM1A SNM1B STRA13 UAF1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBE2T USP1 WDR48 XPF XRCC9
NoRC negatively regulates rRNA expression	AT-rich interactive domain-containing protein 4B Bromodomain adjacent to zinc finger domain protein 2A CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA (cytosine-5)-methyltransferase 1 DNA (cytosine-5)-methyltransferase 3B DNA-directed RNA polymerase I subunit RPA12 DNA-directed RNA polymerase I subunit RPA1 DNA-directed RNA polymerase I subunit RPA2 DNA-directed RNA polymerase I subunit RPA34 DNA-directed RNA polymerase I subunit RPA43 DNA-directed RNA polymerase I subunit RPA49 DNA-directed RNA polymerases I and III subunit RPAC1 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase complex subunit SAP130 Histone deacetylase complex subunit SAP18 Histone deacetylase complex subunit SAP30 Histone deacetylase complex subunit SAP30L Methyl-CpG-binding domain protein 2 Nucleolar transcription factor 1 Paired amphipathic helix protein Sin3a Paired amphipathic helix protein Sin3b Protein POLR1D, isoform 2 SAP30-binding protein SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Sin3 histone deacetylase corepressor complex component SDS3 TATA box-binding protein-associated factor RNA polymerase I subunit A TATA box-binding protein-associated factor RNA polymerase I subunit B TATA box-binding protein-associated factor RNA polymerase I subunit C TATA box-binding protein-associated factor RNA polymerase I subunit D TATA-box-binding protein Transcription termination factor 1	O00422 O15160 O15446 O60264 O60814 O75182 O75446 O95602 P04908 P06899 P0C5Y9 P0DPB5 P16104 P17480 P18074 P19388 P19447 P20226 P20671 P23527 P26358 P32780 P33778 P50613 P51946 P51948 P52434 P53803 P57053 P58876 P61218 P62805 P62807 P62875 P68431 P84243 Q13547 Q13888 Q13889 Q15361 Q15572 Q15573 Q16777 Q16778 Q3B726 Q4LE39 Q53T94 Q6FI13 Q6ZYL4 Q71DI3 Q71UI9 Q8N257 Q92759 Q92769 Q93077 Q93079 Q96A08 Q96ST3 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9GZS1 Q9H0E3 Q9H5J8 Q9H7L9 Q9H9Y6 Q9HAJ7 Q9P1U0 Q9UBB5 Q9UBC3 Q9UHR5 Q9UIF9	AIM ARID4B ASE1 BAZ2A BRCAA1 BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CAST CCNH CD3EAP CDK7 CDKN7 CXXC9 DNMT DNMT1 DNMT3B ERCC2 ERCC3 GTF2D1 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HCNGP HDAC1 HDAC2 HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HTRG HTRP JOSD3 KIAA0314 KIAA0700 MAT1 MBD2 MNAT1 MO15 NS4ATP2 PAF49 PAF53 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1F POLR1G POLR1H POLR2E POLR2F POLR2H POLR2K POLR2L POLRF PRAF1 RBBP1L1 RBP1L1 RNF66 RPA12 RPD3L1 SAP130 SAP18 SAP180 SAP30 SAP30BP SAP30L SAP45 SDS3 SIN3A SIN3B SMARCA5 SNF2H STK1 SUDS3 TAF1A TAF1B TAF1C TAF1D TBP TF2D TFIID TIP5 TSH2B TTDA TTF1 TWISTNB UBF UBF1 UBTF WCRF135 XPB XPBC XPD XPDC ZNRD1
Toxicity of botulinum toxin type C (botC)	Botulinum neurotoxin type C Synaptosomal-associated protein 25 Syntaxin-1A Syntaxin-1B	P18640 P60880 P61266 Q16623	SNAP SNAP25 STX1 STX1A STX1B STX1B1 STX1B2
RHOV GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Actin nucleation-promoting factor WASL Cell division control protein 42 homolog Centriolar coiled-coil protein of 110 kDa Centrosomal protein of 97 kDa Clathrin heavy chain 1 Cytoplasmic protein NCK2 DEP domain-containing protein 1B Disks large homolog 5 Dystonin E3 ubiquitin-protein ligase SH3RF1 Ephrin type-A receptor 2 Inactive tyrosine-protein kinase PEAK1 Mitogen-activated protein kinase kinase kinase 11 Partitioning defective 6 homolog alpha Partitioning defective 6 homolog beta Phosphatidylinositol 3-kinase regulatory subunit alpha Ras GTPase-activating-like protein IQGAP1 Rho GTPase-activating protein 12 Rho guanine nucleotide exchange factor 7 Rho-related GTP-binding protein RhoV SH2/SH3 adapter protein NCK1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase PAK 6 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Thioredoxin-like protein 1 Tropomyosin alpha-3 chain Tropomyosin alpha-4 chain Ubiquitin carboxyl-terminal hydrolase 9X Unconventional myosin-IXa Vang-like protein 1 Zinc finger protein 512B tRNA (34-2'-O)-methyltransferase regulator WDR6	B2RTY4 O00401 O43303 O43396 O43639 O96013 P06753 P16333 P27986 P29317 P46940 P60953 P67936 Q00610 Q01082 Q03001 Q13153 Q13177 Q13813 Q14155 Q14161 Q16584 Q7Z6J0 Q8IW35 Q8IWW6 Q8TAA9 Q8TDM6 Q8WUY9 Q93008 Q96KM6 Q96L33 Q9BYG5 Q9H792 Q9NNW5 Q9NPB6 Q9NQU5 Q9Y2X7	ARHGAP12 ARHGEF7 ARHV BP230 BP240 BPAG1 CCP110 CDC42 CEP110 CEP97 CLH17 CLTC CLTCL2 COOL1 CP110 DEPDC1B DFFRX DLG5 DMH DST DT ECK EPHA2 FAM GIT1 GIT2 GRB1 GRB4 IQGAP1 KIAA0034 KIAA0051 KIAA0142 KIAA0148 KIAA0419 KIAA0583 KIAA0728 KIAA1142 KIAA1196 KIAA1494 KIAA2002 LRRIQ2 MAP3K11 MLK3 MYO9A MYR7 NCK NCK1 NCK2 NEAS P85SPR PAK1 PAK2 PAK3BP PAK4 PAK5 PAK6 PAR6A PAR6B PARD6A PARD6B PDLG PEAK1 PIK3R1 PIXB POSH POSH1 PTK1 RHOV RNF142 SH3MD2 SH3RF1 SPRK SPTA2 SPTAN1 SPTB2 SPTBN1 STB2 TPM3 TPM4 TRP32 TXL TXNL TXNL1 USP9 USP9X VANGL1 WASL WDR6 WRCH2 XTP8 ZNF512B
TP53 Regulates Transcription of Caspase Activators and Caspases	Apoptotic protease-activating factor 1 Caspase-10 Caspase-1 Caspase-2 Caspase-6 Cellular tumor antigen p53 Death domain-containing protein CRADD NLR family CARD domain-containing protein 4 Serine-protein kinase ATM Tumor protein 63 Tumor protein p73 p53-induced death domain-containing protein 1	O14727 O15350 P04637 P29466 P42575 P55212 P78560 Q13315 Q92851 Q9H3D4 Q9HB75 Q9NPP4	APAF1 ATM CARD12 CASP1 CASP10 CASP2 CASP6 CLAN CLAN1 CRADD ICH1 IL1BC IL1BCE IPAF KET KIAA0413 LRDD MCH2 MCH4 NEDD2 NLRC4 P53 P63 P73 P73H P73L PIDD PIDD1 RAIDD TP53 TP63 TP73 TP73L
WNT5:FZD7-mediated leishmania damping	Cytochrome b-245 light chain Frizzled-7 Mitogen-activated protein kinase 8 NADPH oxidase 1 NADPH oxidase activator 1 NADPH oxidase organizer 1 Protein Wnt-5a Ras-related C3 botulinum toxin substrate 1 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Transcription factor Jun	O14640 O14641 O75084 P05412 P13498 P41221 P45983 P63000 Q86UR1 Q8NFA2 Q92997 Q9Y5S8	CYBA DVL1 DVL2 DVL3 FZD7 JNK1 JUN KIAA0208 MAPK8 MOX1 NOH1 NOX1 NOXA1 NOXO1 P41NOX P51NOX PRKM8 RAC1 SAPK1 SAPK1C SH3PXD5 TC25 WNT5A
Activation of RAC1	Cytoplasmic protein NCK2 Ras-related C3 botulinum toxin substrate 1 Roundabout homolog 1 SH2/SH3 adapter protein NCK1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase PAK 6 Slit homolog 2 protein Son of sevenless homolog 1 Son of sevenless homolog 2	O43639 O75914 O94813 O96013 P16333 P63000 Q07889 Q07890 Q13153 Q13177 Q9NQU5 Q9P286 Q9Y6N7	DUTT1 GRB4 KIAA1142 KIAA1264 NCK NCK1 NCK2 OPHN3 PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PAK7 RAC1 ROBO1 SLIL3 SLIT2 SOS1 SOS2 TC25

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