GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Pexophagy	Endothelial PAS domain-containing protein 1 Microtubule-associated proteins 1A/1B light chain 3B Next to BRCA1 gene 1 protein Peroxisomal targeting signal 1 receptor Polyubiquitin-B Polyubiquitin-C Sequestosome-1 Serine-protein kinase ATM Ubiquitin carboxyl-terminal hydrolase 30 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P50542 P62979 P62987 Q13315 Q13501 Q14596 Q70CQ3 Q99814 Q9GZQ8	1A13B ATM BHLHE73 EPAS1 HIF2A KIAA0049 M17S2 MAP1ALC3 MAP1LC3B MOP2 NBR1 ORCA OSIL PASD2 PEX5 PXR1 RPS27A SQSTM1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP30	Homo sapiens (human)
Aberrant regulation of mitotic exit in cancer due to RB1 defects	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Retinoblastoma-associated protein S-phase kinase-associated protein 2 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06400 P30260 P51668 P51965 P60006 Q13042 Q13309 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CDC16 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E E2EPF FBXL1 FYR FZR FZR1 KIAA1242 KIAA1406 RB1 SFT SKP2 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Competing endogenous RNAs (ceRNAs) regulate PTEN translation	Helicase MOV-10 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 CAGH26 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MOV10 TNRC6 TNRC6A TNRC6B TNRC6C	Homo sapiens (human)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43320 O43559 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P21781 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1	Homo sapiens (human)
Tandem pore domain halothane-inhibited K+ channel (THIK)	Potassium channel subfamily K member 13	Q9HB14	KCNK13	Homo sapiens (human)
Activation of BID and translocation to mitochondria	BH3-interacting domain death agonist Caspase-8 Glycylpeptide N-tetradecanoyltransferase 1 Granzyme B	P10144 P30419 P55957 Q14790	BID CASP8 CGL1 CSPB CTLA1 GRB GZMB MCH5 NMT NMT1	Homo sapiens (human)
Formation of the ternary complex, and subsequently, the 43S complex	Eukaryotic translation initiation factor 1A, X-chromosomal Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Ribosomal protein eS27-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00303 O15371 O15372 O75821 O75822 P05198 P08708 P08865 P15880 P20042 P22090 P23396 P25398 P39019 P41091 P42677 P46781 P46782 P46783 P47813 P55884 P60228 P60866 P61247 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62701 P62753 P62841 P62847 P62851 P62854 P62857 P62861 P62979 P63220 Q13347 Q14152 Q71UM5 Q7L2H7 Q8TD47 Q99613 Q9UBQ5 Q9Y262	CCG2 D6S218E EIF1A EIF1AX EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3C EIF3D EIF3E EIF3EIP EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF3S1 EIF3S10 EIF3S12 EIF3S2 EIF3S3 EIF3S4 EIF3S5 EIF3S6 EIF3S6IP EIF3S7 EIF3S8 EIF3S9 EIF4C FAU FTE1 HFLB5 INT6 KIAA0139 LAMBR LAMR1 MFTL MPS1 PCID1 RIG RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA SCAR TRIP1 UBA80 UBCEP1	Homo sapiens (human)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi-associated PDZ and coiled-coil motif-containing protein Rho-related GTP-binding protein RhoQ	P13569 P17081 Q9HD26	ABCC7 ARHQ CAL CFTR FIG GOPC RASL7A RHOQ TC10	Homo sapiens (human)
Alpha-oxidation of phytanate	2-hydroxyacyl-CoA lyase 1 Long-chain fatty acid transport protein 2 Peroxisomal membrane protein PMP34 Peroxisomal trans-2-enoyl-CoA reductase Phytanoyl-CoA dioxygenase, peroxisomal	O14832 O14975 O43808 Q9BY49 Q9UJ83	ACSVL1 FACVL1 FATP2 HACL1 HPCL HPCL2 PAHX PECR PHYH PHYH2 PMP34 SDR29C1 SLC25A17 SLC27A2 VLACS	Homo sapiens (human)
Regulation of ornithine decarboxylase (ODC)	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Antizyme inhibitor 1 NAD(P)H dehydrogenase [quinone] 1 Ornithine decarboxylase antizyme 1 Ornithine decarboxylase antizyme 2 Ornithine decarboxylase antizyme 3 Ornithine decarboxylase Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7	O00231 O00232 O00487 O14818 O14977 O43242 O95190 P11926 P15559 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P54368 P60896 P60900 P62191 P62195 P62333 Q13200 Q15008 Q16186 Q99436 Q99460 Q9UMX2 Q9UNM6	ADRM1 AZIN1 C7orf76 DIA4 DSS1 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NMOR1 NQO1 NU OAZ OAZ1 OAZ2 OAZ3 OAZI OAZIN ODC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 X Y Z	Homo sapiens (human)
TGFBR2 Kinase Domain Mutants in Cancer	TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein	P01137 P36897 P37173	ALK5 SKR4 TGFB TGFB1 TGFBR1 TGFBR2	Homo sapiens (human)
Defective GGT1 causes GLUTH	Glutathione hydrolase 1 proenzyme	P19440	GGT GGT1	Homo sapiens (human)
Defective CHST3 causes SEDCJD	Biglycan Brevican core protein Carbohydrate sulfotransferase 3 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q7LGC8 Q96GW7	BCAN BEHAB BGN CALEB CHST3 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN	Homo sapiens (human)
Retinoid metabolism and transport	Agrin Aldo-keto reductase family 1 member B10 Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1 member C3 Aldo-keto reductase family 1 member C4 All-trans-retinol 13,14-reductase Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Apolipoprotein M Basement membrane-specific heparan sulfate proteoglycan core protein Beta,beta-carotene 15,15'-dioxygenase Carotenoid-cleaving dioxygenase, mitochondrial Colipase Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Lecithin retinol acyltransferase Lipoprotein lipase Low-density lipoprotein receptor-related protein 10 Low-density lipoprotein receptor-related protein 12 Low-density lipoprotein receptor-related protein 2 Low-density lipoprotein receptor-related protein 8 Low-density lipoprotein receptor Pancreatic triacylglycerol lipase Phospholipase B1, membrane-associated Prolow-density lipoprotein receptor-related protein 1 Retinol dehydrogenase 11 Retinol-binding protein 1 Retinol-binding protein 2 Retinol-binding protein 4 Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Transthyretin	O00468 O60218 O75056 O75487 O95237 O95445 P01130 P02647 P02649 P02652 P02655 P02656 P02753 P02766 P04114 P04118 P06727 P06858 P09455 P16233 P17516 P18827 P31431 P34741 P35052 P42330 P50120 P51654 P78333 P98160 P98164 Q04828 Q07954 Q14114 Q6NUM9 Q6P1J6 Q7Z4F1 Q8IV16 Q8N158 Q8TC12 Q9BYV7 Q9HAY6 Q9Y561 Q9Y625	A2MR AGRIN AGRN AKR1B10 AKR1B11 AKR1C1 AKR1C3 AKR1C4 APC2 APOA1 APOA2 APOA4 APOB APOC2 APOC3 APOE APOER2 APOM APR ARSDR1 BCDO BCDO1 BCDO2 BCMO1 BCO1 BCO2 CHDR CLPS CRBP1 CRBP2 DDH DDH1 G3A GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 GPIHBP1 HBP1 HSD17B5 HSPG1 HSPG2 KIAA0119 KIAA0468 LDLR LIPD LPL LRAT LRP1 LRP10 LRP12 LRP2 LRP8 NG20 OCI5 PALB PGFS PLB PLB1 PNLIP PPSIG PSDR1 RBP1 RBP2 RBP4 RDH11 RETSAT SDC SDC1 SDC2 SDC3 SDC4 SDR7C1 ST7 TTR	Homo sapiens (human)
ChREBP activates metabolic gene expression	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha ATP-citrate synthase Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 Carbohydrate-responsive element-binding protein Fatty acid synthase Max-like protein X	O00763 P49327 P53396 Q13085 Q99943 Q9NP71 Q9UH92	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB ACLY AGPAT1 BHLHD13 BHLHD14 FAS FASN G15 MIO MLX MLXIPL TCFL4 WBSCR14	Homo sapiens (human)
Truncations of AMER1 destabilize the destruction complex	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Glycogen synthase kinase-3 beta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O15169 P25054 P30153 P30154 P48729 P49841 P62714 P67775 Q13362 Q14738 Q15172 Q15173 Q16537 Q5JTC6	AMER1 APC AXIN AXIN1 CSNK1A1 DP2.5 FAM123B GSK3B KIAA0044 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WTX	Homo sapiens (human)
CD28 co-stimulation	GRB2-related adapter protein 2 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O75791 P06239 P06241 P07947 P07948 P10747 P33681 P42081	CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 FYN GADS GRAP2 GRB2L GRID JTK8 LAB7 LCK LYN YES YES1	Homo sapiens (human)
DAP12 interactions	Beta-2-microglobulin C-type lectin domain family 5 member A CMRF35-like molecule 2 CMRF35-like molecule 7 HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E Killer cell immunoglobulin-like receptor 2DS2 Killer cell immunoglobulin-like receptor 2DS4 Killer cell immunoglobulin-like receptor 2DS5 Killer cell immunoglobulin-like receptor 3DS1 NKG2-C type II integral membrane protein NKG2-D type II integral membrane protein Natural cytotoxicity triggering receptor 2 Natural killer cells antigen CD94 Sialic acid-binding Ig-like lectin 14 Sialic acid-binding Ig-like lectin 15 Sialic acid-binding Ig-like lectin 16 Signal-regulatory protein beta-1 TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 1 Triggering receptor expressed on myeloid cells 2	A6NMB1 A8K4G0 O00241 O43914 O95944 P01889 P10321 P13747 P26717 P26718 P43631 P43632 P61769 Q08ET2 Q13241 Q14943 Q14953 Q496F6 Q6ZMC9 Q9NP99 Q9NY25 Q9NZC2	B2M CD158G CD158I CD158J CD300B CD300E CD300LB CD300LE CD33L3 CD94 CLEC5A CLECSF5 CLM2 CLM7 CMRF35A2 CMRF35A5 D12S2489E DAP12 HLA-6.2 HLA-B HLA-C HLA-E HLAB HLAC HLAE IREM2 IREM3 KARAP KIR2DS2 KIR2DS4 KIR2DS5 KIR3DS1 KKA3 KLRC2 KLRD1 KLRK1 LMIR5 LY95 MDL1 NCR2 NKAT10 NKAT5 NKAT8 NKAT9 NKG2C NKG2D SIGLEC14 SIGLEC15 SIGLEC16 SIGLECP16 SIRPB1 TREM1 TREM2 TREM5 TYROBP	Homo sapiens (human)
COPI-dependent Golgi-to-ER retrograde traffic	ADP-ribosylation factor 1 ADP-ribosylation factor 3 ADP-ribosylation factor 4 ADP-ribosylation factor 5 ADP-ribosylation factor GTPase-activating protein 1 ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 Alpha-soluble NSF attachment protein Beta-soluble NSF attachment protein Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Chromosome-associated kinesin KIF4A Chromosome-associated kinesin KIF4B Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma-1 Coatomer subunit gamma-2 Coatomer subunit zeta-1 Coatomer subunit zeta-2 ER lumen protein-retaining receptor 1 ER lumen protein-retaining receptor 2 ER lumen protein-retaining receptor 3 Gamma-soluble NSF attachment protein Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Kinesin heavy chain isoform 5A Kinesin light chain 1 Kinesin light chain 2 Kinesin light chain 3 Kinesin light chain 4 Kinesin-1 heavy chain Kinesin-associated protein 3 Kinesin-like protein (Fragment) Kinesin-like protein (Fragment) Kinesin-like protein KIF11 Kinesin-like protein KIF12 Kinesin-like protein KIF13B Kinesin-like protein KIF15 Kinesin-like protein KIF16B Kinesin-like protein KIF18A Kinesin-like protein KIF18B Kinesin-like protein KIF19 Kinesin-like protein KIF1A Kinesin-like protein KIF1B Kinesin-like protein KIF1C Kinesin-like protein KIF20A Kinesin-like protein KIF20B Kinesin-like protein KIF21A Kinesin-like protein KIF21B Kinesin-like protein KIF22 Kinesin-like protein KIF23 Kinesin-like protein KIF25 Kinesin-like protein KIF26A Kinesin-like protein KIF26B Kinesin-like protein KIF27 Kinesin-like protein KIF28P Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinesin-like protein KIF3A Kinesin-like protein KIF3B Kinesin-like protein KIF3C Kinesin-like protein KIF6 Kinesin-like protein KIF9 Kinesin-like protein KIFC1 Kinesin-like protein KIFC2 NBAS subunit of NRZ tethering complex RAD50-interacting protein 1 Rac GTPase-activating protein 1 Ras-related protein Rab-1A Ras-related protein Rab-1B Surfeit locus protein 4 Syntaxin-18 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Transmembrane emp24 domain-containing protein 3 Transmembrane emp24 domain-containing protein 7 Transmembrane emp24 domain-containing protein 9 Vesicle transport protein SEC20 Vesicle transport protein USE1 Vesicle-fusing ATPase Vesicle-trafficking protein SEC22b	A2RRP1 B7ZC32 O00139 O14579 O14782 O15066 O15260 O43264 O43731 O43896 O60333 O75037 O75396 O95235 O95239 P18085 P24390 P33176 P33947 P35606 P46459 P48444 P49755 P52732 P53618 P53621 P54920 P61204 P61923 P62820 P84077 P84085 Q02224 Q02241 Q07866 Q12756 Q12840 Q12981 Q14807 Q15363 Q2KJY2 Q2TAC6 Q2VIQ3 Q66K46 Q6NUQ1 Q6P597 Q6PKD1 Q6ZMV9 Q7Z4S6 Q86VH2 Q86Y91 Q8N4N8 Q8N6H7 Q8N6T3 Q8NI77 Q92538 Q92845 Q96AC6 Q96FN5 Q96L93 Q96Q89 Q99661 Q99747 Q9BVK6 Q9BW19 Q9H0B6 Q9H0H5 Q9H0U4 Q9H115 Q9HAQ2 Q9NP61 Q9NQT8 Q9NS87 Q9NSK0 Q9NZ43 Q9P299 Q9P2W9 Q9UBF2 Q9UIL4 Q9ULI4 Q9Y3B3 Q9Y3Q3 Q9Y496 Q9Y678	ARCN1 ARF1 ARF1GAP ARF2 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 ATSV BNIP1 C15orf22 C20orf23 C2orf20 C6orf102 CENPE COPA COPB COPB1 COPB2 COPD COPE COPG COPG1 COPG2 COPZ COPZ1 COPZ2 EG5 ERD2.1 ERD2.2 ERD23 GAKIN GBF1 GP25L2 HSET KDELR1 KDELR2 KDELR3 KIAA0248 KIAA0359 KIAA0449 KIAA0591 KIAA0639 KIAA0706 KIAA1236 KIAA1448 KIAA1478 KIAA1590 KIAA1708 KID KIF11 KIF12 KIF13B KIF15 KIF16B KIF18A KIF18B KIF19 KIF1A KIF1B KIF1C KIF2 KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF25 KIF26A KIF26B KIF27 KIF28P KIF2A KIF2B KIF2C KIF3 KIF3A KIF3AP KIF3B KIF3C KIF4 KIF4A KIF4B KIF5A KIF5B KIF5C KIF6 KIF9 KIFAP3 KIFC1 KIFC2 KLC KLC1 KLC2 KLC2L KLC3 KLC4 KLP2 KLP6 KNS KNS1 KNS2 KNSL1 KNSL2 KNSL3 KNSL4 KNSL5 KNSL6 KNSL7 KNSL8 KRMP1 MGCRACGAP MKLP1 MKLP2 MPHOSPH1 NAG NAPA NAPB NAPG NBAS NIP1 NKHC1 NSF RAB1 RAB1A RAB1B RAB6KIFL RACGAP1 RINT1 RNP24 SEC20L SEC22B SEC22L1 SMAP SNAPA SNAPB SNAPG SNX23 STX18 SURF-4 SURF4 TMED10 TMED2 TMED3 TMED7 TMED9 TMP21 TRIP5 USE1 USE1L ZNF289 ZW10	Homo sapiens (human)
Signaling by RAF1 mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P31946 P32121 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q6VAB6 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 NRAS PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VCL VWF YWHAB	Homo sapiens (human)
RAS processing	ADP-ribosylation factor-like protein 2 Acyl-protein thioesterase 1 Alpha/beta hydrolase domain-containing protein 17A Alpha/beta hydrolase domain-containing protein 17B Alpha/beta hydrolase domain-containing protein 17C Bcl-2-like protein 1 CAAX prenyl protease 2 Calmodulin-1 GTPase HRas GTPase KRas GTPase NRas Golgin subfamily A member 7 Palmitoyltransferase ZDHHC9 Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C theta type Protein-S-isoprenylcysteine O-methyltransferase Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Ubiquitin carboxyl-terminal hydrolase 17 cGMP-dependent protein kinase 2	O43924 O60725 O75608 P01111 P01112 P01116 P0DP23 P36404 P49354 P49356 Q04759 Q07817 Q13237 Q5VST6 Q6PCB6 Q6R6M4 Q7Z5G4 Q96GS6 Q9Y256 Q9Y397	ABHD17A ABHD17B ABHD17C APT1 ARL2 BCL2L BCL2L1 BCLX C19orf27 C9orf77 CALM CALM1 CAM CAM1 CXorf11 DUB3 FACE2 FAM108A1 FAM108B1 FAM108C1 FNTA FNTB GCP16 GOLGA7 HRAS HRAS1 ICMT KRAS KRAS2 LPL1 LYPLA1 NRAS PCCMT PDE6D PDED PRKCQ PRKCT PRKG2 PRKGR2 RASK2 RCE1 RCE1A RCE1B USP17 USP17H USP17I USP17J USP17K USP17L USP17L2 USP17M ZDHHC10 ZDHHC9 ZNF379 ZNF380	Homo sapiens (human)
G alpha (z) signalling events	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C gamma type Protein kinase C theta type Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 19 Regulator of G-protein signaling 20 Regulator of G-protein signaling 4 Regulator of G-protein signaling protein-like	A5PLK6 A8MTJ3 O14610 O14775 O15492 O43306 O60262 O60266 O60503 O76081 O95622 P04899 P05129 P05771 P08754 P08913 P16520 P17252 P18089 P18825 P19086 P24723 P40145 P49795 P49798 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q02156 Q04759 Q05655 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UGC6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR GAIP GNAI1 GNAI2 GNAI2B GNAI3 GNAI3IP GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKCA PKCB PKCD PKCE PKCG PKCL PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCE PRKCG PRKCH PRKCL PRKCQ PRKCT RGS16 RGS17 RGS19 RGS20 RGS4 RGSL RGSL1 RGSL2 RGSR RGSZ1 RGSZ2 ZGAP1	Homo sapiens (human)
Methionine salvage pathway	Acireductone dioxygenase Aspartate aminotransferase, cytoplasmic Enolase-phosphatase E1 Methylthioribose-1-phosphate isomerase Methylthioribulose-1-phosphate dehydratase S-methyl-5'-thioadenosine phosphorylase	P17174 Q13126 Q96GX9 Q9BV20 Q9BV57 Q9UHY7	ADI1 APIP ENOPH1 GOT1 MASA MRDI MRI1 MSAP MTAP MTCBP1	Homo sapiens (human)
Defective DPM1 causes CDG-1e	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9	O15520 O43320 O76093 P05230 P08620 P09038 P10767 P11487 P19174 P21781 P31371 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 PLC1 PLCG1	Homo sapiens (human)

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