GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **926 - 950** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
A tetrasaccharide linker sequence is required for GAG synthesis	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Beta-1,3-galactosyltransferase 6 Beta-1,4-galactosyltransferase 7 Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Neurocan core protein Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Versican core protein Xylosyltransferase 1 Xylosyltransferase 2	O00468 O14594 O75056 O75487 O94766 O95196 P07585 P13611 P18827 P21810 P31431 P34741 P35052 P51654 P78333 P98160 Q6UVK1 Q86Y38 Q8N158 Q96GW7 Q96L58 Q9H1B5 Q9NPZ5 Q9P2W7 Q9UBV7 Q9Y625	AGRIN AGRN B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 BCAN BEHAB BGN CALEB CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN GLCATP GLCATS GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HSPG1 HSPG2 KIAA0468 KIAA1963 MCSP NCAN NEUR NGC OCI5 SDC SDC1 SDC2 SDC3 SDC4 SLRR1A SLRR1B VCAN XGALT1 XT1 XT2 XYLT1 XYLT2	Homo sapiens (human)
Defensins	Beta-defensin (Fragment) Beta-defensin 103 Beta-defensin 104 Beta-defensin 105 Beta-defensin 106 Beta-defensin 107 Beta-defensin 108B Beta-defensin 110 Beta-defensin 112 Beta-defensin 113 Beta-defensin 114 Beta-defensin 115 Beta-defensin 116 Beta-defensin 119 Beta-defensin 121 Beta-defensin 123 Beta-defensin 124 Beta-defensin 125 Beta-defensin 126 Beta-defensin 127 Beta-defensin 128 Beta-defensin 129 Beta-defensin 130A Beta-defensin 130B Beta-defensin 131A Beta-defensin 132 Beta-defensin 133 Beta-defensin 134 Beta-defensin 135 Beta-defensin 1 Defensin alpha 4 Defensin alpha 5 Defensin beta 118 Defensin beta 136 Defensin beta 4A Defensin-6 Neutrophil defensin 1 Neutrophil defensin 3	O15263 P0DP73 P0DP74 P12838 P59665 P59666 P59861 P60022 P81534 Q01523 Q01524 Q30KP8 Q30KP9 Q30KQ1 Q30KQ3 Q30KQ4 Q30KQ5 Q30KQ6 Q30KQ7 Q30KQ8 Q30KQ9 Q4QY38 Q5J5C9 Q7Z7B7 Q7Z7B8 Q8IZN7 Q8N104 Q8N687 Q8N688 Q8N690 Q8NES8 Q8NET1 Q8NG35 Q8WTQ1 Q96PH6 Q9BYW3 Q9H1M3 Q9H1M4	BD1 BD3 BD5 BD6 C20orf63 C20orf73 C20orf8 C20orf87 DEF1 DEF3 DEF4 DEF5 DEF6 DEFA1 DEFA1B DEFA2 DEFA3 DEFA4 DEFA5 DEFA6 DEFB1 DEFB10 DEFB102 DEFB103 DEFB103A DEFB103B DEFB104 DEFB104A DEFB104B DEFB105 DEFB105A DEFB105B DEFB106 DEFB106A DEFB106B DEFB107 DEFB107A DEFB107B DEFB108 DEFB108B DEFB11 DEFB110 DEFB111 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB117 DEFB118 DEFB119 DEFB12 DEFB120 DEFB121 DEFB123 DEFB124 DEFB125 DEFB126 DEFB127 DEFB128 DEFB129 DEFB13 DEFB130 DEFB130A DEFB130B DEFB131 DEFB131A DEFB132 DEFB133 DEFB134 DEFB135 DEFB136 DEFB14 DEFB15 DEFB16 DEFB18 DEFB19 DEFB2 DEFB20 DEFB21 DEFB23 DEFB24 DEFB25 DEFB26 DEFB27 DEFB28 DEFB29 DEFB3 DEFB30 DEFB31 DEFB32 DEFB4 DEFB4A DEFB4B DEFB5 DEFB6 DEFB7 DEFB8 ESC42 HBD1 MRS	Homo sapiens (human)
Interleukin-9 signaling	Cytokine receptor common subunit gamma Interleukin-9 receptor Interleukin-9 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3	P15248 P23458 P31785 P40763 P42224 P42229 P51692 P52333 Q01113	APRF IL2RG IL9 IL9R JAK1 JAK1A JAK1B JAK3 STAT1 STAT3 STAT5 STAT5A STAT5B	Homo sapiens (human)
P2Y receptors	Lysophosphatidic acid receptor 4 Lysophosphatidic acid receptor 6 P2Y purinoceptor 11 P2Y purinoceptor 12 P2Y purinoceptor 13 P2Y purinoceptor 14 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y purinoceptor 4 P2Y purinoceptor 6 Putative P2Y purinoceptor 10 Uracil nucleotide/cysteinyl leukotriene receptor	O00398 P41231 P43657 P47900 P51582 Q13304 Q15077 Q15391 Q96G91 Q99677 Q9BPV8 Q9H244	GPR105 GPR17 GPR23 GPR86 GPR94 HORK3 KIAA0001 LPA4 LPAR4 LPAR6 NRU P2RU1 P2RY1 P2RY10 P2RY11 P2RY12 P2RY13 P2RY14 P2RY2 P2RY4 P2RY5 P2RY6 P2RY9	Homo sapiens (human)
Biosynthesis of Lipoxins (LX)	15-hydroxyprostaglandin dehydrogenase [NAD(+)] Arachidonate 5-lipoxygenase-activating protein Leukotriene C4 synthase Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX12 Prostaglandin reductase 1	P09917 P15428 P18054 P20292 Q14914 Q16873	12LO ALOX12 ALOX5 ALOX5AP FLAP HPGD LOG12 LOG5 LTB4DH LTC4S PGDH1 PTGR1 SDR36C1	Homo sapiens (human)
U12 Dependent Splicing	116 kDa U5 small nuclear ribonucleoprotein component ATP-dependent RNA helicase DDX42 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Pre-mRNA-processing factor 6 Pre-mRNA-processing-splicing factor 8 Probable ATP-dependent RNA helicase DDX23 Programmed cell death protein 7 RNA-binding region-containing protein 3 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Splicing factor 3B subunit 1 Splicing factor 3B subunit 2 Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Splicing factor 3B subunit 5 Splicing factor 3B subunit 6 Thioredoxin-like protein 4A U11/U12 small nuclear ribonucleoprotein 25 kDa protein U11/U12 small nuclear ribonucleoprotein 35 kDa protein U11/U12 small nuclear ribonucleoprotein 48 kDa protein U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 U5 small nuclear ribonucleoprotein 200 kDa helicase U5 small nuclear ribonucleoprotein 40 kDa protein Y-box-binding protein 1 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 Zinc finger matrin-type protein 5	O15514 O75533 O75643 O94906 P13984 P14678 P19387 P19388 P24928 P30876 P35269 P36954 P52298 P52434 P52435 P53803 P61218 P62304 P62306 P62308 P62314 P62316 P62318 P62487 P62875 P67809 P83876 Q01130 Q07955 Q09161 Q13247 Q13435 Q15029 Q15393 Q15427 Q15696 Q16560 Q16629 Q6IEG0 Q6P2Q9 Q86XP3 Q8N8D1 Q8TBF4 Q96DI7 Q96LT9 Q9BUQ8 Q9BV90 Q9BWJ5 Q9UDW3 Q9Y3B4	ASCC3L1 ASF BRR2 C16orf33 C20orf14 C6orf151 CBP20 CBP80 COD DDX23 DDX42 DIM1 EFTUD2 GTF2F1 GTF2F2 HELIC2 HM1 KIAA0017 KIAA0031 KIAA0788 KIAA1839 NCBP NCBP1 NCBP2 NSEP1 PBSCF PBSCG PDCD7 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PRP8BP PRPC8 PRPF6 PRPF8 RAP30 RAP74 RBM40 RNP RNPC3 RPB7 SAP130 SAP14 SAP145 SAP155 SAP49 SF2 SF2P33 SF3B1 SF3B10 SF3B14 SF3B14A SF3B2 SF3B3 SF3B4 SF3B5 SF3B6 SFP38 SFRS1 SFRS2 SFRS6 SFRS7 SNRNP200 SNRNP25 SNRNP35 SNRNP40 SNRNP48 SNRNP65 SNRP116 SNRPB SNRPB1 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP55 SRSF1 SRSF2 SRSF6 SRSF7 TXNL4 TXNL4A U1SNRNPBP U2AF1-RS2 U2AF1L2 U2AF1RS2 URP WDR57 YB1 YBX1 ZCRB1 ZMAT5 ZRSR2	Homo sapiens (human)
Biotin transport and metabolism	Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 Biotin--protein ligase Biotinidase Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial PDZ domain-containing protein 11 Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate carboxylase, mitochondrial Sodium-dependent multivitamin transporter	O00763 P05165 P05166 P11498 P43251 P50747 Q13085 Q5EBL8 Q96RQ3 Q9HCC0 Q9Y289	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB AIPP1 BTD HLCS MCCA MCCB MCCC1 MCCC2 PC PCCA PCCB PDZD11 PDZK11 PISP SLC5A6 SMVT	Homo sapiens (human)
NIK-->noncanonical NF-kB signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme Ubc12 Nuclear factor NF-kappa-B p100 subunit Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 S-phase kinase-associated protein 1 Transcription factor RelB Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O15111 O43242 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P61081 P62191 P62195 P62333 P62979 P62987 P63208 Q00653 Q01201 Q13200 Q13616 Q15008 Q16186 Q8TBC4 Q99436 Q99460 Q99558 Q9UKB1 Q9UNM6 Q9Y297	ADRM1 BTRC BTRCP BTRCP2 C7orf76 CHUK CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B GP110 HC2 HC3 HC8 HC9 HSPC IKKA KIAA0107 KIAA0696 LMPX LMPY LYT10 MAP3K14 MB1 MIP224 MOV34L MSS1 NFKB2 NIK NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RELB RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TCF16 TRAP2 UBA3 UBA52 UBA80 UBB UBC UBC12 UBCEP1 UBCEP2 UBE1C UBE2M X Y Z	Homo sapiens (human)
Dermatan sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 14 Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Dermatan-sulfate epimerase-like protein Dermatan-sulfate epimerase Neurocan core protein Uronyl 2-sulfotransferase Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q8IZU8 Q8NCH0 Q96GW7 Q9UL01 Q9Y2C2	BCAN BEHAB BGN C18orf4 CALEB CHST14 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 D4ST1 DCN DS2ST DSE DSEL MCSP NCAG1 NCAN NEUR NGC SART2 SLRR1A SLRR1B UST VCAN	Homo sapiens (human)
IRAK4 deficiency (TLR2/4)	Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain High mobility group protein B1 Interleukin-1 receptor-associated kinase 4 Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Protein S100-A1 Protein S100-A8 Protein S100-A9 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK	O00206 O60603 P02671 P02675 P02679 P05109 P06702 P08571 P09429 P16671 P23297 P26623 P30690 P58753 Q06187 Q15399 Q99836 Q9NWZ3 Q9Y2C9 Q9Y6Y9	AGMX1 ATK BPK BTK CAGA CAGB CD14 CD36 CFAG ESOP1 FGA FGB FGG GP3B GP4 HMG1 HMGB1 IRAK4 KIAA0012 LY96 MAL MD2 MRP14 MRP8 MYD88 S100A S100A1 S100A8 S100A9 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 mip porB	Homo sapiens (human)
Defective DNA double strand break response due to BRCA1 loss of function	BRCA1-associated RING domain protein 1 Breast cancer type 1 susceptibility protein	P38398 Q99728	BARD1 BRCA1 RNF53	Homo sapiens (human)
Uptake and function of anthrax toxins	Calmodulin-1 Calmodulin-sensitive adenylate cyclase Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 Furin Lethal factor Programmed cell death 6-interacting protein Protective antigen	O14733 P09958 P0DP23 P13423 P15917 P36507 P40136 P45985 Q02750 Q8WUM4	AIP1 ALIX CALM CALM1 CAM CAM1 FUR FURIN JNKK1 JNKK2 KIAA1375 MAP2K1 MAP2K2 MAP2K4 MAP2K7 MEK1 MEK2 MEK4 MEK7 MKK2 MKK4 MKK7 PACE PCSK3 PDCD6IP PRKMK1 PRKMK2 PRKMK4 PRKMK7 SEK1 SERK1 SKK1 SKK4 cya lef pag pagA	Homo sapiens (human)
Mitotic Prometaphase	Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 20 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 SKA complex subunit 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 2 ZW10 interactor	O00139 O14576 O14777 O14980 O15392 O43237 O43264 O43683 O43684 O60566 O75122 O95229 P30153 P30154 P30622 P36873 P42677 P43034 P46060 P49450 P49454 P49792 P50748 P53350 P55735 P57740 P62714 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14738 Q15172 Q15173 Q15691 Q16537 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q8N0S6 Q8N2Z9 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NI77 Q8WUM0 Q8WVK7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96EA4 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NXR1 Q9P258 Q9Y266 Q9Y6D9 Q9Y6G9	AHCTF1 AIK2 AIM1 AIRK2 API4 APITD1 ARK2 AURKB B9D2 BIRC5 BUB1 BUB1B BUB1L BUB3 BUBR1 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 CASC5 CCDC99 CDC20 CDCA1 CDCA8 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CYLN1 D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ELYS EOPA ERCC6L FAAP16 FAM33A FSHPRH1 HDLC1 HEC HEC1 IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0097 KIAA0166 KIAA0197 KIAA0325 KIAA0622 KIAA0627 KIAA1361 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MCM21R MDCR MDS MHF1 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MPS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PESCRG3 PICH PLK PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RANBP2 RANGAP1 RCC2 ROD RPS27 RSN SD SEC13 SEC13A SEC13L1 SEC13R SGO1 SGO2 SGOL1 SGOL2 SKA1 SKA2 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STK1 STK12 STK5 TAOK1 TD60 TMBS62 TXBP181 XPO1 ZW10 ZWILCH ZWINT	Homo sapiens (human)
Purine ribonucleoside monophosphate biosynthesis	Adenylosuccinate lyase Adenylosuccinate synthetase isozyme 1 Adenylosuccinate synthetase isozyme 2 Amidophosphoribosyltransferase Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase Bifunctional purine biosynthesis protein ATIC GMP synthase [glutamine-hydrolyzing] Inosine-5'-monophosphate dehydrogenase 1 Inosine-5'-monophosphate dehydrogenase 2 Phosphoribosylformylglycinamidine synthase Trifunctional purine biosynthetic protein adenosine-3	O15067 P12268 P20839 P22102 P22234 P30520 P30566 P31939 P49915 Q06203 Q8N142	ADE2 ADSL ADSS ADSS1 ADSS2 ADSSL1 AIRC AMPS ATIC GART GMPS GPAT IMPD1 IMPD2 IMPDH1 IMPDH2 KIAA0361 PAICS PAIS PFAS PGFT PPAT PRGS PURH	Homo sapiens (human)
Early Phase of HIV Life Cycle	DNA ligase 1 Flap endonuclease 1 Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04618 P05919 P18858 P39748 P62937 P69723 P69726	CYPA FEN1 LIG1 PPIA RAD2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
PI-3K cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	O15520 O43320 O76093 P05230 P08620 P09038 P10767 P11487 P21781 P27986 P31371 P42336 Q06124 Q13480 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 GAB1 GRB1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 PIK3CA PIK3R1 PTP2C PTPN11 SHPTP2	Homo sapiens (human)
MyD88 dependent cascade initiated on endosome	Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 7 Toll-like receptor 9	O43187 P51617 Q99836 Q9NR96 Q9NWZ3 Q9NYK1 Q9Y4K3	IRAK IRAK1 IRAK2 IRAK4 MYD88 RNF85 TLR7 TLR9 TRAF6	Homo sapiens (human)
Plasmalogen biosynthesis	Alkyldihydroxyacetonephosphate synthase, peroxisomal Dehydrogenase/reductase SDR family member 7B Dihydroxyacetone phosphate acyltransferase	O00116 O15228 Q6IAN0	AGPS DAPAT DHAPAT DHRS7B GNPAT SDR32C1	Homo sapiens (human)
LXRs regulate gene expression linked to lipogenesis	Angiopoietin-related protein 3 Fatty acid synthase Nuclear receptor-interacting protein 1 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Stearoyl-CoA desaturase	O00767 P19793 P28702 P48552 P49327 P55055 Q13133 Q9Y5C1	ANGPT5 ANGPTL3 FADS5 FAS FASN LXRA LXRB NER NR1H2 NR1H3 NR2B1 NR2B2 NRIP1 RXRA RXRB SCD SCD1 SCDOS UNR	Homo sapiens (human)
Attachment of GPI anchor to uPAR	GPI inositol-deacylase GPI transamidase component PIG-S GPI transamidase component PIG-T GPI-anchor transamidase Glycosylphosphatidylinositol anchor attachment 1 protein Phosphatidylinositol glycan anchor biosynthesis class U protein Urokinase plasminogen activator surface receptor	O43292 Q03405 Q75T13 Q92643 Q969N2 Q96S52 Q9H490	CDC91L1 GAA1 GPAA1 GPI8 MO3 PGAP1 PIGK PIGS PIGT PIGU PLAUR UPAR	Homo sapiens (human)
FGFR4 mutant receptor activation	Fibroblast growth factor receptor 4	P22455	FGFR4 JTK2 TKF	Homo sapiens (human)
Erythropoietin activates Phospholipase C gamma (PLCG)	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Erythropoietin receptor Erythropoietin Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O60674 P01588 P07948 P16885 P19174 P19235 Q9Y4H2	EPO EPOR IRS2 JAK2 JTK8 LYN PLC1 PLCG1 PLCG2	Homo sapiens (human)
Mitotic Prophase	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Nuclear mitotic apparatus protein 1	P06493 P14635 Q14980	CCNB CCNB1 CDC2 CDC28A CDK1 CDKN1 NMP22 NUMA NUMA1 P34CDC2	Homo sapiens (human)
Constitutive Signaling by EGFRvIII	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 E3 ubiquitin-protein ligase CBL Epidermal growth factor receptor GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor SHC-transforming protein 1 Son of sevenless homolog 1	P00533 P01111 P01112 P01133 P07900 P19174 P22681 P27986 P29353 P42336 Q07889 Q13480 Q16543	CBL CBL2 CDC37 CDC37A EGF EGFR ERBB ERBB1 GAB1 GRB1 HER1 HRAS HRAS1 HSP90A HSP90AA1 HSPC1 HSPCA NRAS PIK3CA PIK3R1 PLC1 PLCG1 RNF55 SHC SHC1 SHCA SOS1	Homo sapiens (human)
Inositol transporters	Proton myo-inositol cotransporter Sodium/myo-inositol cotransporter 2 Sodium/myo-inositol cotransporter	P53794 Q8WWX8 Q96QE2	KST1 SLC2A13 SLC5A11 SLC5A3 SLGTX SMIT2	Homo sapiens (human)

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