GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **826 - 850** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
Gap junction degradation	AP-2 complex subunit mu Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disabled homolog 2 Dynamin-1 Dynamin-2 Gap junction alpha-1 protein Unconventional myosin-VI	P09496 P09497 P17302 P50570 P53675 P98082 Q00610 Q05193 Q96CW1 Q9UM54	AP2M1 CLAPM1 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DAB2 DNM DNM1 DNM2 DOC2 DYN2 GJA1 GJAL KIAA0034 KIAA0109 KIAA0389 MYO6
Formation of annular gap junctions	AP-2 complex subunit mu Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disabled homolog 2 Dynamin-1 Dynamin-2 Gap junction alpha-1 protein	P09496 P09497 P17302 P50570 P53675 P98082 Q00610 Q05193 Q96CW1	AP2M1 CLAPM1 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DAB2 DNM DNM1 DNM2 DOC2 DYN2 GJA1 GJAL KIAA0034 KIAA0109
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	Apolipoprotein E Protein DEK Transcription factor AP-2-alpha	P02649 P05549 P35659	AP2TF APOE DEK TFAP2 TFAP2A
TFAP2 (AP-2) family regulates transcription of other transcription factors	Cbp/p300-interacting transactivator 2 Pituitary homeobox 2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P05549 Q92754 Q99697 Q99967	AP2TF ARP1 CITED2 MRG1 PITX2 RGS RIEG RIEG1 TFAP2 TFAP2A TFAP2C
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain-containing protein 2 Choriogonadotropin subunit beta 3 Epidermal growth factor receptor Estrogen receptor Glycoprotein hormones alpha chain Mast/stem cell growth factor receptor Kit Protransforming growth factor alpha Receptor tyrosine-protein kinase erbB-2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcriptional repressor protein YY1 Vascular endothelial growth factor A, long form	P00533 P01135 P01215 P03372 P04626 P05549 P0DN86 P10721 P15692 P25490 Q6PL18 Q92481 Q92754	AP2TF ATAD2 CGA CGB CGB3 CGB5 CGB8 EGFR ERBB ERBB1 ERBB2 ESR ESR1 HER1 HER2 INO80S KIT MLN19 NEU NGL NR3A1 SCFR TFAP2 TFAP2A TFAP2B TFAP2C TGFA VEGF VEGFA YY1
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Cyclin-dependent kinase inhibitor 1 Lysine-specific demethylase 5B Myc proto-oncogene protein Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P01106 P05549 P38936 Q92754 Q9UGL1	AP2TF BHLHE39 CAP20 CDKN1 CDKN1A CIP1 JARID1B KDM5B MDA6 MYC PIC1 PLU1 RBBP2H1 SDI1 TFAP2 TFAP2A TFAP2C WAF1
Specification of the neural plate border	Bone morphogenetic protein 4 Catenin beta-1 Fibroblast growth factor 4 Homeobox protein DLX-5 Homeobox protein GBX-2 Homeobox protein MSX-1 POU domain, class 5, transcription factor 1 Paired box protein Pax-3 Paired box protein Pax-7 Protein Wnt-3a Transcription factor 7-like 1 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor SOX-2 Transcriptional activator Myb Zinc finger protein ZIC 1	P05549 P08620 P10242 P12644 P23759 P23760 P28360 P35222 P48431 P52951 P56178 P56704 Q01860 Q15915 Q92481 Q92754 Q9HCS4	AP2TF BMP2B BMP4 CTNNB CTNNB1 DLX5 DVR4 FGF4 GBX2 HOX7 HST HSTF1 HUP1 HUP2 KS3 MSX1 MYB OCT3 OCT4 OTF3 PAX3 PAX7 POU5F1 SOX2 TCF3 TCF7L1 TFAP2 TFAP2A TFAP2B TFAP2C WNT3A ZIC ZIC1 ZNF201
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	60 kDa heat shock protein, mitochondrial Myb-related protein B Nucleophosmin Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase Transcription factor AP-2-alpha	P05549 P06748 P10244 P10809 P46087	AP2TF BMYB HSP60 HSPD1 MYBL2 NOL1 NOP2 NPM NPM1 NSUN1 TFAP2 TFAP2A
Negative regulation of activity of TFAP2 (AP-2) family transcription factors	BTB/POZ domain-containing protein KCTD15 BTB/POZ domain-containing protein KCTD1 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor AP-2-delta Transcription factor AP-2-epsilon WW domain-containing oxidoreductase	P05549 P63165 P63279 Q6VUC0 Q719H9 Q7Z6R9 Q92481 Q92754 Q96SI1 Q9NZC7	AP2TF C18orf5 FOR KCTD1 KCTD15 SDR41C1 SMT3C SMT3H3 SUMO1 TFAP2 TFAP2A TFAP2B TFAP2BL1 TFAP2C TFAP2D TFAP2E UBC9 UBCE9 UBE2I UBL1 WOX1 WWOX
Activation of the TFAP2 (AP-2) family of transcription factors	CREB-binding protein Cbp/p300-interacting transactivator 1 Cbp/p300-interacting transactivator 2 Cbp/p300-interacting transactivator 4 Histone acetyltransferase p300 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcription factor AP-2-delta Transcription factor AP-2-epsilon WW domain-containing oxidoreductase YEATS domain-containing protein 4	O95619 P05549 Q09472 Q6VUC0 Q7Z6R9 Q92481 Q92754 Q92793 Q96RK1 Q99966 Q99967 Q9NZC7	AP2TF CBP CITED1 CITED2 CITED4 CREBBP EP300 FOR GAS41 MRG1 MRG2 MSG1 P300 SDR41C1 TFAP2 TFAP2A TFAP2B TFAP2BL1 TFAP2C TFAP2D TFAP2E WOX1 WWOX YEATS4
Regulation of the apoptosome activity	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP Methylthioribulose-1-phosphate dehydratase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Uveal autoantigen with coiled-coil domains and ankyrin repeats	O14727 P27361 P28482 P55211 P98170 P99999 Q96GX9 Q9BZF9 Q9NQS1 Q9NR28 Q9Y2G2	APAF1 API3 APIP AVEN BIRC4 CARD8 CASP9 CYC CYCS DACAR DIABLO ERK1 ERK2 IAP3 KIAA0413 KIAA0955 KIAA1561 MAPK1 MAPK3 MCH6 NDPP1 PRKM1 PRKM2 PRKM3 SMAC UACA XIAP
SMAC (DIABLO) binds to IAPs	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP
Activation of caspases through apoptosome-mediated cleavage	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS IAP3 KIAA0413 MCH3 MCH6 XIAP
Formation of apoptosome	Apoptotic protease-activating factor 1 Caspase recruitment domain-containing protein 8 Caspase-9 Cell death regulator Aven Cytochrome c Methylthioribulose-1-phosphate dehydratase	O14727 P55211 P99999 Q96GX9 Q9NQS1 Q9Y2G2	APAF1 APIP AVEN CARD8 CASP9 CYC CYCS DACAR KIAA0413 KIAA0955 MCH6 NDPP1
TP53 Regulates Transcription of Caspase Activators and Caspases	Apoptotic protease-activating factor 1 Caspase-10 Caspase-1 Caspase-2 Caspase-6 Cellular tumor antigen p53 Death domain-containing protein CRADD NLR family CARD domain-containing protein 4 Serine-protein kinase ATM Tumor protein 63 Tumor protein p73 p53-induced death domain-containing protein 1	O14727 O15350 P04637 P29466 P42575 P55212 P78560 Q13315 Q92851 Q9H3D4 Q9HB75 Q9NPP4	APAF1 ATM CARD12 CASP1 CASP10 CASP2 CASP6 CLAN CLAN1 CRADD ICH1 IL1BC IL1BCE IPAF KET KIAA0413 LRDD MCH2 MCH4 NEDD2 NLRC4 P53 P63 P73 P73H P73L PIDD PIDD1 RAIDD TP53 TP63 TP73 TP73L
Transcriptional Regulation by E2F6	Apoptotic protease-activating factor 1 Breast cancer type 1 susceptibility protein Cell division cycle 7-related protein kinase Chromobox protein homolog 3 Chromobox protein homolog 5 DNA endonuclease RBBP8 DNA repair protein RAD51 homolog 1 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Enhancer of polycomb homolog 1 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Histone-lysine N-methyltransferase EZH2 Lethal(3)malignant brain tumor-like protein 2 MAX gene-associated protein Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polycomb group RING finger protein 6 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 3 Protein UXT Protein max RING1 and YY1-binding protein Ribonucleoside-diphosphate reductase subunit M2 Serine/threonine-protein kinase Chk1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F6 YY1-associated factor 2	O00311 O14727 O14757 O75461 O75530 P31350 P35226 P35227 P38398 P45973 P61244 P78364 Q01094 Q06587 Q06609 Q09028 Q13185 Q14186 Q14188 Q15022 Q15910 Q16576 Q8IWI9 Q8IY57 Q8N488 Q8NDX5 Q969R5 Q96KQ7 Q99496 Q99708 Q9BYE7 Q9H2F5 Q9H9B1 Q9UBK9	APAF1 BAP1 BAT8 BHLHD4 BMI1 BRCA1 C6orf30 CBX3 CBX5 CDC7 CDC7L1 CHEK1 CHET9 CHK1 CTIP DEDAF DING DP1 DP2 E2F1 E2F6 EDR1 EDR3 EED EHMT1 EHMT2 EPC1 EUHMTASE1 EZH2 G9A GLP HIPI3 HP1A JJAZ1 KIAA0160 KIAA0413 KIAA0518 KIAA1876 KMT1C KMT1D KMT6 L3MBTL2 MAD5 MAX MBLR MEL18 MGA NG36 PCGF2 PCGF4 PCGF6 PH1 PH3 PHC1 PHC3 RAD51 RAD51A RBAP46 RBAP48 RBBP3 RBBP4 RBBP7 RBBP8 RECA RING1 RING1A RING1B RNF1 RNF110 RNF134 RNF2 RNF51 RNF53 RR2 RRM2 RYBP SUZ12 TFDP1 TFDP2 UXT YAF2 YEAF1 ZNF144
Neurexins and neuroligins	Amyloid-beta A4 precursor protein-binding family A member 1 Amyloid-beta A4 precursor protein-binding family A member 2 Amyloid-beta A4 precursor protein-binding family A member 3 Band 4.1-like protein 1 Band 4.1-like protein 2 Band 4.1-like protein 3 Band 4.1-like protein 5 Brain-enriched guanylate kinase-associated protein Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Disks large-associated protein 1 Disks large-associated protein 2 Disks large-associated protein 3 Disks large-associated protein 4 Drebrin-like protein Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Homer protein homolog 1 Homer protein homolog 2 Homer protein homolog 3 Leucine-rich repeat transmembrane neuronal protein 1 Leucine-rich repeat transmembrane neuronal protein 2 Leucine-rich repeat transmembrane neuronal protein 3 Leucine-rich repeat transmembrane neuronal protein 4 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 5 Neurexin-1-beta Neurexin-1 Neurexin-2-beta Neurexin-2 Neurexin-3-beta Neurexin-3 Neuroligin-1 Neuroligin-2 Neuroligin-3 Neuroligin-4, X-linked Neuroligin-4, Y-linked PDZ and LIM domain protein 5 Peripheral plasma membrane protein CASK Protein 4.1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C SH3 and multiple ankyrin repeat domains protein 1 SH3 and multiple ankyrin repeat domains protein 2 SH3 and multiple ankyrin repeat domains protein 3 Sharpin Signal-induced proliferation-associated 1-like protein 1 Synaptotagmin-10 Synaptotagmin-12 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-7 Synaptotagmin-9 Syntaxin-1A Syntaxin-binding protein 1	O14490 O14910 O14936 O15399 O43166 O43300 O43491 O43581 O95886 O96018 P11171 P21579 P41594 P58400 P58401 P61764 P78352 Q02410 Q05586 Q12879 Q13224 Q13255 Q14957 Q15700 Q16623 Q6XYQ8 Q86SS6 Q86UE6 Q86VH4 Q86VH5 Q86YM7 Q8IV01 Q8N0W4 Q8N2Q7 Q8N9I0 Q8NFZ3 Q8NFZ4 Q92796 Q96HC4 Q99767 Q9BUH8 Q9BYB0 Q9H0F6 Q9H4G0 Q9HAP6 Q9HCM4 Q9HDB5 Q9NSB8 Q9NSC5 Q9NUP9 Q9NZ94 Q9P1A6 Q9P2S2 Q9UJU6 Q9ULB1 Q9UPX8 Q9Y2H0 Q9Y2J2 Q9Y4C0 Q9Y566	APBA1 APBA2 APBA3 BEGAIN C14orf60 C8orf68 CASK CMAP CORTBP1 DAL1 DAP1 DAP2 DAP3 DAP4 DBNL DLG2 DLG3 DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 E41P E6TP1 ENH EPB41 EPB41L1 EPB41L2 EPB41L3 EPB41L5 ERICH1-AS1 GKAP GPRC1A GPRC1E GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRM1 GRM5 GluN2D HOMER1 HOMER2 HOMER3 KIAA0338 KIAA0416 KIAA0440 KIAA0578 KIAA0743 KIAA0921 KIAA0951 KIAA0964 KIAA0987 KIAA1022 KIAA1070 KIAA1232 KIAA1260 KIAA1366 KIAA1446 KIAA1480 KIAA1548 KIAA1650 LIN2 LIN7A LIN7B LIN7C LRRN2 LRRTM1 LRRTM2 LRRTM3 LRRTM4 MALS1 MALS2 MALS3 MGLUR1 MGLUR5 MINT1 MINT2 MINT3 NL3 NLGN1 NLGN2 NLGN3 NLGN4 NLGN4X NLGN4Y NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D NRXN1 NRXN2 NRXN3 PCANAP7 PDLIM5 PROSAP1 PROSAP2 PSAP2 PSD95 SAPAP4 SH3P7 SHANK1 SHANK2 SHANK3 SHARPIN SIPA1L1 SIPL1 STX1 STX1A STXBP1 SVP65 SYN47 SYT SYT1 SYT10 SYT12 SYT2 SYT7 SYT9 UNC18A VELI1 VELI2 VELI3 X11 X11L X11L2
Dopamine Neurotransmitter Release Cycle	Amyloid-beta A4 precursor protein-binding family A member 1 Complexin-1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral plasma membrane protein CASK Peripheral-type benzodiazepine receptor-associated protein 1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2	O14795 O14810 O14910 O14936 O14994 O75145 O75334 O75335 O95153 P17600 P20336 P21579 P60880 P63027 Q02410 Q05940 Q13136 Q16623 Q86UR5 Q92777 Q9HAP6 Q9NUP9	APBA1 BZRAP1 CASK CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIN2 LIN7A LIN7B LIN7C LIP1 MALS1 MALS2 MALS3 MINT1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A2 SNAP SNAP25 STX1 STX1A SVMT SVP65 SYB2 SYN1 SYN2 SYN3 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VELI1 VELI2 VELI3 VMAT2 X11
Signaling downstream of RAS mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB
Signaling by moderate kinase activity BRAF mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB
Paradoxical activation of RAF signaling by kinase inactive BRAF	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB
Signaling by RAF1 mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P31946 P32121 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q6VAB6 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 NRAS PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VCL VWF YWHAB
MAP2K and MAPK activation	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Interleukin-17 receptor D Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Vinculin WD repeat domain-containing protein 83 von Willebrand factor	P01111 P01112 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q6VAB6 Q7Z5R6 Q8IVT5 Q8NFM7 Q8WXI2 Q969H4 Q9BRX9 Q9UHA4 Q9Y2Q5 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IL17RD IL17RLM IQGAP1 ITGA2B ITGAB ITGB3 KIAA0051 KIAA0902 KIAA1027 KREV1 KSR KSR1 KSR2 LAMTOR2 LAMTOR3 MAP2K1 MAP2K1IP1 MAP2K2 MAPBPIP MAPK1 MAPK3 MAPKSP1 MARK3 MEK1 MEK2 MKK2 MORG1 NRAS PBP PEBP PEBP1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RIAM ROBLD3 SEF SRC SRC1 TLN TLN1 VCL VWF WDR83 YWHAB
Signaling by high-kinase activity BRAF mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Vinculin von Willebrand factor	P01111 P01112 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q6VAB6 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 KIAA0051 KIAA0902 KIAA1027 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 NRAS PBP PEBP PEBP1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VCL VWF YWHAB

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