GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **851 - 875** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	GlyTouCan ID
p130Cas linkage to MAPK signaling for integrins	Adapter molecule crk Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Breast cancer anti-estrogen resistance protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1A Ras-related protein Rap-1b Talin-1 von Willebrand factor	P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P46108 P56945 P61224 P62834 Q05397 Q7Z5R6 Q9Y490	APBB1IP BCAR1 CAS CASS1 CRK CRKAS F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 PREL1 PTK2 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VWF
GRB2:SOS provides linkage to MAPK signaling for Integrins	Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin alpha-IIb Integrin beta-3 Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1A Ras-related protein Rap-1b Son of sevenless homolog 1 Talin-1 von Willebrand factor	P02671 P02675 P02679 P02751 P04275 P05106 P08514 P12931 P61224 P62834 Q05397 Q07889 Q7Z5R6 Q9Y490	APBB1IP F8VWF FAK FAK1 FGA FGB FGG FN FN1 GP2B GP3A ITGA2B ITGAB ITGB3 KIAA1027 KREV1 PREL1 PTK2 RAP1A RAP1B RARP1 RIAM SOS1 SRC SRC1 TLN TLN1 VWF
APC truncation mutants are not K63 polyubiquitinated	Adenomatous polyposis coli protein	P25054	APC DP2.5
Chylomicron remodeling	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 Lipoprotein lipase	P02647 P02649 P02652 P02655 P02656 P04114 P06727 P06858 Q6Q788 Q8IV16	APC2 APOA1 APOA2 APOA4 APOA5 APOB APOC2 APOC3 APOE GPIHBP1 HBP1 LIPD LPL RAP3
Chylomicron assembly	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase Small COPII coat GTPase SAR1B	P02647 P02649 P02652 P02655 P02656 P04114 P06727 P07237 P55157 Q9Y6B6	APC2 APOA1 APOA2 APOA4 APOB APOC2 APOC3 APOE ERBA2L MTP MTTP P4HB PDI PDIA1 PO4DB SAR1B SARA2 SARB
PCNA-Dependent Long Patch Base Excision Repair	DNA ligase 1 DNA polymerase beta DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA repair nuclease/redox regulator APEX1 Flap endonuclease 1 Proliferating cell nuclear antigen Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P06746 P12004 P15927 P18858 P27694 P27695 P28340 P35244 P35249 P35250 P35251 P39748 P40937 P40938 P49005 P56282 Q07864 Q15054 Q9HCU8 Q9NR33 Q9NRF9	APE APE1 APEX APEX1 APX CHRAC17 DPE2 FEN1 HAP1 KIAA0039 LIG1 PCNA POLB POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 RAD2 REF1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway	DNA polymerase beta DNA repair nuclease/redox regulator APEX1	P06746 P27695	APE APE1 APEX APEX1 APX HAP1 POLB REF1
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	DNA polymerase beta DNA repair nuclease/redox regulator APEX1	P06746 P27695	APE APE1 APEX APEX1 APX HAP1 POLB REF1
Resolution of Abasic Sites (AP sites)	DNA repair nuclease/redox regulator APEX1	P27695	APE APE1 APEX APEX1 APX HAP1 REF1
Eukaryotic Translation Termination	Acylamino-acid-releasing enzyme Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Eukaryotic peptide chain release factor GTP-binding subunit ERF3B Eukaryotic peptide chain release factor subunit 1 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Methyltransferase N6AMT1 Multifunctional methyltransferase subunit TRM112-like protein Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P05386 P05387 P05388 P08708 P08865 P13798 P15170 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P39019 P39023 P40429 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P50914 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62495 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q6P5R6 Q71UM5 Q8IYD1 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q9UI30 Q9UNX3 Q9Y3U8 Q9Y5N5	APEH BBC1 C21orf127 CCG2 D11S2243E D3F15S2 D3S48E D6S218E DNF15S2 DXS648E EC45 ERF1 ERF3A ERF3B ETF1 FAU FTE1 GSPT1 GSPT2 HEMK2 KMT9 LAMBR LAMR1 MFTL MPS1 N6AMT1 NEDD6 PRED28 QM RF1 RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SUP45L1 SURF-3 SURF3 TRMT112 TXREB1 UBA52 UBA80 UBCEP1 UBCEP2
PINK1-PRKN Mediated Mitophagy	Autophagy protein 5 E3 ubiquitin-protein ligase parkin Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM22 homolog Mitochondrial import receptor subunit TOM40 homolog Mitochondrial import receptor subunit TOM5 homolog Mitochondrial import receptor subunit TOM6 homolog Mitochondrial import receptor subunit TOM7 homolog Mitochondrial import receptor subunit TOM70 Mitofusin-1 Mitofusin-2 Polyubiquitin-B Polyubiquitin-C Sequestosome-1 Serine/threonine-protein kinase PINK1, mitochondrial Transcription termination factor 3, mitochondrial Ubiquitin-like protein ATG12 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Voltage-dependent anion-selective channel protein 1	O60260 O94817 O94826 O95140 O96008 P0CG47 P0CG48 P21796 P62979 P62987 Q13501 Q15388 Q8IWA4 Q8N4H5 Q96B49 Q96E29 Q9BXM7 Q9GZQ8 Q9H1Y0 Q9H492 Q9NS69 Q9P0U1	APG12 APG12L APG5L ASP ATG12 ATG5 C19orf1 C9orf105 CPRP1 KIAA0016 KIAA0214 KIAA0719 MAP1ALC3 MAP1LC3A MAP1LC3B MFN1 MFN2 MTERF3 MTERFD1 OBTP ORCA OSIL PARK2 PEREC1 PINK1 PRKN RPS27A SQSTM1 TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOMM07 TOMM20 TOMM22 TOMM40 TOMM5 TOMM6 TOMM7 TOMM70 TOMM70A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VDAC VDAC1
Negative regulators of RIG-I/MDA5 signaling	Antiviral innate immune response receptor RIG-I Autophagy protein 5 E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RNF125 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase RNF216 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein NLR family member X1 OTU domain-containing protein 5 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Poly(rC)-binding protein 2 Polyubiquitin-B Polyubiquitin-C Protein NLRC5 Serine/threonine-protein kinase TBK1 TNF receptor-associated factor 3 Tax1-binding protein 1 Tumor necrosis factor alpha-induced protein 3 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 K Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ATG12 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 O94817 O95786 P05161 P0CG47 P0CG48 P21580 P41226 P51668 P61077 P61086 P62837 P62979 P62987 Q13114 Q13526 Q14164 Q14258 Q14653 Q15366 Q7Z434 Q86UT6 Q86VP1 Q86WI3 Q8IUD6 Q96EQ8 Q96G74 Q96J02 Q9BYX4 Q9C037 Q9H1Y0 Q9NQC7 Q9NWF9 Q9UHD2 Q9UII4	APG12 APG12L APG5L ASP ATG12 ATG5 CAP-1 CEB1 CEBP1 CRAF1 CYLD CYLD1 DDX58 EFP G1P2 HERC5 HIP2 IFIH1 IKBKE IKKE IKKI IPS1 IRF3 ISG15 ITCH KIAA0151 KIAA0849 KIAA1271 LIG MAVS MDA5 NAK NLRC5 NLRX1 NOD27 NOD4 NOD5 NOD9 OTUD5 OTUD7C PCBP2 PIN1 PUBC1 RH116 RIGI RNF125 RNF135 RNF147 RNF216 RNF87 RPS27A SFT T6BP TAX1BP1 TBK1 TNFAIP3 TRAF3 TRAFAMN TRIAD3 TRIM25 TRIM4 UBA52 UBA7 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCE7IP1 UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBCH8 UBE1L UBE2 UBE2D1 UBE2D2 UBE2D3 UBE2K UBE2L6 UCRP VISA ZIN ZNF147
Receptor Mediated Mitophagy	Autophagy protein 5 Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta FUN14 domain-containing protein 1 Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Serine/threonine-protein kinase ULK1 Ubiquitin-like protein ATG12	O75385 O94817 P19784 P67870 P68400 Q8IVP5 Q9GZQ8 Q9H1Y0 Q9H492	APG12 APG12L APG5L ASP ATG12 ATG5 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B FUNDC1 G5A KIAA0722 MAP1ALC3 MAP1LC3A MAP1LC3B ULK1
Regulation of TNFR1 signaling	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CAP-Gly domain-containing linker protein 3 Caspase-8 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase subunit epsilon MAP kinase-activated protein kinase 2 NF-kappa-B essential modulator OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin Polyubiquitin-B Polyubiquitin-C RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Serine proteinase inhibitor 2 Serine proteinase inhibitor 2 Serine/threonine-protein kinase TBK1 Serine/threonine-protein kinase ULK1 Sharpin Signal peptide peptidase-like 2A Signal peptide peptidase-like 2B Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TNF receptor-associated factor 1 TNF receptor-associated factor 2 Tax1-binding protein 1 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin thioesterase otulin Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein UL36	O14920 O15111 O75385 O75604 P01375 P07385 P0CG47 P0CG48 P15059 P16767 P19438 P21580 P49137 P51668 P61077 P62837 P62979 P62987 P63244 P68036 P98170 Q12933 Q13077 Q13107 Q13158 Q13489 Q13490 Q13546 Q14164 Q14790 Q15628 Q5VV17 Q6GQQ9 Q86VP1 Q8TCT7 Q8TCT8 Q96AX9 Q96BN8 Q96CV9 Q96DZ5 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9UHD2 Q9UK80 Q9UM82 Q9UNE7 Q9Y6K9	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CASP8 CHIP CHUK CLIP3 CLIPR59 CYLD CYLD1 DUBA7 EBI6 FADD FAM105B FIP2 FIP3 GLC1E GNB2L1 HIP7 HYPL IAP3 IKBKB IKBKE IKBKG IKKA IKKB IKKE IKKI IMP3 IMP4 KIAA0151 KIAA0722 KIAA0757 KIAA0849 KIAA1532 MAPKAPK2 MCH5 MIB2 MIHB MIHC MORT1 NAK NEMO NRP OPG199 OPTN OTDC1 OTUD1 OTUD7B OTUD7C OTULIN PD1 PSL1 PSL2 PUBC1 RACK1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 RPS27A SFT SHARPIN SIPL1 SKD SPATA2 SPI-2 SPPL2A SPPL2B STUB1 T6BP TAX1BP1 TBK1 TCF16 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF1 TRAF2 TRAP3 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCE7 UBCE7IP3 UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBCH7 UBE2D1 UBE2D2 UBE2D3 UBE2L3 UBP41 UL36 ULK1 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA ZZANK1
TNFR1-induced proapoptotic signaling	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase-8 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP FAS-associated death domain protein Inhibitor of nuclear factor kappa-B kinase subunit epsilon OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Serine/threonine-protein kinase TBK1 Sharpin Spermatogenesis-associated protein 2 TNF receptor-associated factor 2 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Uncharacterized protein UL36	O75604 P01375 P16767 P19438 P21580 P98170 Q12933 Q13107 Q13158 Q13489 Q13490 Q13546 Q14164 Q14790 Q15628 Q5VV17 Q6GQQ9 Q96AX9 Q96CV9 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9UHD2 Q9UK80 Q9UM82	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CASP8 CYLD CYLD1 DUBA7 FADD FIP2 GLC1E HIP7 HYPL IAP3 IKBKE IKKE IKKI KIAA0151 KIAA0757 KIAA0849 MCH5 MIB2 MIHB MIHC MORT1 NAK NRP OPTN OTDC1 OTUD1 OTUD7B OTUD7C PD1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 SHARPIN SIPL1 SKD SPATA2 TBK1 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF2 TRAP3 UBCE7IP3 UBP41 UL36 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA ZZANK1
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Sharpin Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 1 TNF receptor-associated factor 2 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD	O14920 O15111 O43318 O75604 P01375 P19438 P21580 P63244 P98170 Q12933 Q13077 Q13107 Q13489 Q13490 Q13546 Q15628 Q15750 Q5VV17 Q6GQQ9 Q8N5C8 Q96CV9 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9NYJ8 Q9UK80 Q9UM82 Q9Y6K9	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CHUK CYLD CYLD1 DUBA7 EBI6 FIP2 FIP3 GLC1E GNB2L1 HIP7 HYPL IAP3 IKBKB IKBKG IKKA IKKB KIAA0733 KIAA0757 KIAA0849 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MIHB MIHC NEMO NRP OPTN OTDC1 OTUD1 OTUD7B OTUD7C PD1 RACK1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 SHARPIN SIPL1 SPATA2 TAB1 TAB2 TAB3 TAK1 TCF16 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF1 TRAF2 TRAP3 UBCE7IP3 UBP41 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA
TNFR2 non-canonical NF-kB pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 TNF receptor-associated factor 2 TNF receptor-associated factor 3 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 12 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor receptor superfamily member 11A Tumor necrosis factor receptor superfamily member 12A Tumor necrosis factor receptor superfamily member 13C Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor superfamily member 3 Tumor necrosis factor	A5LHX3 O00231 O00232 O00233 O00487 O14788 O14818 O43242 O43508 O43557 O75832 P01374 P01375 P17980 P20333 P20618 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P29965 P35998 P36941 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 Q06323 Q06643 Q12933 Q13114 Q13200 Q13489 Q13490 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q96RJ3 Q99436 Q99460 Q99558 Q9NP84 Q9UL46 Q9UNM6 Q9Y275 Q9Y6Q6	API1 API2 APO3L BAFF BAFFR BIRC2 BIRC3 BLYS BR3 C7orf76 CAP-1 CD40L CD40LG CRAF1 D12S370 DR3LG DSS1 FN14 HC2 HC3 HC8 HC9 HSPC HVEML IFI5111 KIAA0072 KIAA0077 KIAA0107 LIGHT LMP10 LMP2 LMP7 LMPX LMPY LTA LTB LTBR MAP3K14 MB1 MCB1 MECL1 MIHB MIHC MIP224 MOV34L MSS1 NIK NU OPGL PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RANK RANKL RING10 RING12 RNF48 RNF49 SEM1 SHFDG1 SHFM1 SUG1 SUG2 TALL1 TBP1 TBP7 TNF TNFA TNFB TNFBR TNFC TNFCR TNFR2 TNFR3 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF1B TNFRSF3 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF2 TNFSF20 TNFSF3 TNFSF5 TRAF2 TRAF3 TRAFAMN TRANCE TRAP TRAP2 TRAP3 X Y Y2 Z ZTNF4
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor-associated factor 2 TNF receptor-associated factor 3 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 12 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor receptor superfamily member 11A Tumor necrosis factor receptor superfamily member 12A Tumor necrosis factor receptor superfamily member 13C Tumor necrosis factor receptor superfamily member 3	O14788 O43508 O43557 P01374 P29965 P36941 Q06643 Q12933 Q13114 Q13489 Q13490 Q96RJ3 Q99558 Q9NP84 Q9Y275 Q9Y6Q6	API1 API2 APO3L BAFF BAFFR BIRC2 BIRC3 BLYS BR3 CAP-1 CD40L CD40LG CRAF1 D12S370 DR3LG FN14 HVEML LIGHT LTA LTB LTBR MAP3K14 MIHB MIHC NIK OPGL RANK RANKL RNF48 RNF49 TALL1 TNFB TNFC TNFCR TNFR3 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF3 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF20 TNFSF3 TNFSF5 TRAF2 TRAF3 TRAFAMN TRANCE TRAP TRAP3 ZTNF4
IKK complex recruitment mediated by RIP1	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NF-kappa-B essential modulator Polyubiquitin-B Polyubiquitin-C Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 O14920 O15111 P08571 P0CG47 P0CG48 P51668 P61077 P61088 P62837 P62979 P62987 Q13404 Q13489 Q13490 Q13546 Q86XR7 Q8IUC6 Q9Y4K3 Q9Y572 Q9Y6K9 Q9Y6Y9	API1 API2 BIRC2 BIRC3 BLU CD14 CHUK CROC1 ESOP1 FIP3 IKBKB IKBKG IKKA IKKB LY96 MD2 MIHB MIHC NEMO PRVTIRB PUBC1 RIP RIP1 RIP3 RIPK1 RIPK3 RNF48 RNF49 RNF85 RPS27A SFT TCF16 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF6 TRAM TRIF UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 UBE2N UBE2V UBE2V1 UEV1
TICAM1, RIP1-mediated IKK complex recruitment	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator Polyubiquitin-B Polyubiquitin-C Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 6 Toll-like receptor 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 O15111 O15455 P0CG47 P0CG48 P51668 P61077 P61088 P62837 P62979 P62987 Q13404 Q13489 Q13490 Q13546 Q8IUC6 Q9Y4K3 Q9Y572 Q9Y6K9	API1 API2 BIRC2 BIRC3 BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB MIHB MIHC NEMO PRVTIRB PUBC1 RIP RIP1 RIP3 RIPK1 RIPK3 RNF48 RNF49 RNF85 RPS27A SFT TCF16 TICAM1 TLR3 TRAF6 TRIF UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 UBE2N UBE2V UBE2V1 UEV1
SMAC, XIAP-regulated apoptotic response	Caspase-3 Caspase-7 Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	P42574 P55210 P98170 Q9NR28	API3 BIRC4 CASP3 CASP7 CPP32 DIABLO IAP3 MCH3 SMAC XIAP
Regulation of PTEN localization	E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin-protein ligase XIAP Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Protein PML Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P29590 P46934 P60484 P62979 P62987 P98170 Q93009	API3 BIRC4 HAUSP IAP3 KIAA0093 MMAC1 MYL NEDD4 NEDD4-1 PML PP8675 PTEN RNF71 RPF1 RPS27A TEP1 TRIM19 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 XIAP
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Apoptosis facilitator Bcl-2-like protein 14 Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 B-cell lymphoma 6 protein Baculoviral IAP repeat-containing protein 5 Cellular tumor antigen p53 Geranylgeranyl transferase type-2 subunit alpha Geranylgeranyl transferase type-2 subunit beta Protein NDRG1 Quinone oxidoreductase PIG3 Rab proteins geranylgeranyltransferase component A 1 Tumor protein 63 Tumor protein p73 p53 apoptosis effector related to PMP-22	O15350 O15392 P04637 P24386 P41182 P53611 Q13625 Q53FA7 Q92597 Q92696 Q96FX8 Q96KQ4 Q9BZR8 Q9H3D4	API4 ASPP1 ASPP2 BBP BCL2L14 BCL5 BCL6 BCLG BIRC5 CAP43 CHM DRG1 GGTB IAP4 KCP1 KET KIAA0771 KRTCAP1 LAZ3 NDRG1 P53 P63 P73 P73H P73L PERP PIG3 PIGPC1 PPP1R13B RABGGTA RABGGTB REP1 RTP TCD THW TP53 TP53BP2 TP53I3 TP63 TP73 TP73L ZBTB27 ZNF51
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein C Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere protein W Centromere protein X Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3-like centromeric protein A Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Holliday junction recognition protein Kinetochore scaffold 1 Mis18-binding protein 1 Nucleophosmin Protein Mis18-alpha Protein Mis18-beta Remodeling and spacing factor 1 RuvB-like 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	A8MT69 O43482 O60264 O60814 P04908 P06748 P06899 P0C5Y9 P16104 P20671 P23527 P33778 P49450 P57053 P58876 P62805 P62807 Q03188 Q09028 Q13352 Q16576 Q16777 Q16778 Q5EE01 Q6FI13 Q6IPU0 Q6P0N0 Q71F23 Q71UI9 Q7L2Z9 Q8N0S6 Q8N257 Q8N2Z9 Q8NCD3 Q8NG31 Q92674 Q93077 Q93079 Q96A08 Q96BT3 Q96H22 Q96T23 Q99877 Q99878 Q99879 Q99880 Q9BS16 Q9BTM1 Q9BU64 Q9H3R5 Q9NSP4 Q9NYP9 Q9Y265	APITD1 C14orf106 C16orf56 C16orf60 C1orf155 C21orf45 C21orf46 C22orf18 C6orf139 C6orf173 CASC5 CENPA CENPC CENPC1 CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CENPW CENPX CUG2 FAAP10 FAAP16 FAKTS FASP1 FLEG1 FSHPRH1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HBXAP HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HJURP ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INO80H ITGB3BP KIAA1570 KIAA1903 KLIP1 KNL1 KNL2 LRPR1 M18BP1 MCM21R MHF1 MHF2 MIS18A MIS18B MIS18BP1 MLF1IP NMP238 NPM NPM1 NRIF3 OIP5 PANE1 PBIP1 RBAP46 RBAP48 RBBP4 RBBP7 RSF1 RUVBL1 SMARCA5 SNF2H STRA13 TIP49 TIP49A TSH2B URLC9 WCRF135 XAP8
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta CD44 antigen Calcineurin B homologous protein 1 Hyaluronan mediated motility receptor Hyaluronidase-1 Hyaluronidase-2 Hyaluronidase-3 Lymphatic vessel endothelial hyaluronic acid receptor 1 Sodium/hydrogen exchanger 1 Stabilin-2	O43820 O75330 P06865 P07686 P08236 P16070 P19634 Q12794 Q12891 Q8WWQ8 Q99653 Q9Y5Y7	APNH1 CD44 CHP CHP1 CRSBP1 FEEL2 FELL FEX2 GUSB HAR HARE HEXA HEXB HMMR HYAL1 HYAL2 HYAL3 IHABP LHR LUCA1 LUCA2 LUCA3 LYVE1 MDU2 MDU3 MIC4 NHE1 RHAMM SLC9A1 STAB2 XLKD1	G35674CY

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