GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1151 - 1175** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
Defective CHSY1 causes TPBS	Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Chondroitin sulfate synthase 1 Decorin Neurocan core protein Versican core protein	O14594 O95196 P07585 P13611 P21810 Q6UVK1 Q86X52 Q96GW7	BCAN BEHAB BGN CALEB CHSY CHSY1 CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 CSS1 DCN KIAA0990 MCSP NCAN NEUR NGC SLRR1A SLRR1B VCAN
SCF(Skp2)-mediated degradation of p27/p21	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinases regulatory subunit 1 G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein-tyrosine kinase 6 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00233 O00487 O14818 O43242 O75832 O96020 P0CG47 P0CG48 P11802 P17980 P20248 P20618 P24385 P24864 P24941 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P38936 P40306 P43686 P46527 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61024 P61289 P62191 P62195 P62333 P62979 P62987 P63208 P78396 Q06323 Q13200 Q13309 Q13616 Q13882 Q15008 Q16401 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	BCL1 BRK C7orf76 CAP20 CCN1 CCNA CCNA1 CCNA2 CCND1 CCNE CCNE1 CCNE2 CDK2 CDK4 CDKN1 CDKN1A CDKN1B CDKN2 CIP1 CKS1 CKS1B CUL1 DSS1 EMC19 FBXL1 HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0107 KIP1 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MDA6 MECL1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 PIC1 POH1 PRAD1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 PTK6 RING10 RING12 RPS27A SDI1 SEM1 SHFDG1 SHFM1 SKP1 SKP1A SKP2 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAF1 X Y Y2 Z p27
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Protein-tyrosine kinase 6	P11802 P24385 P24864 P24941 P46527 Q13882	BCL1 BRK CCND1 CCNE CCNE1 CDK2 CDK4 CDKN1B CDKN2 KIP1 PRAD1 PTK6 p27
Ubiquitin-dependent degradation of Cyclin D	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cyclin-dependent kinase 4 G1/S-specific cyclin-D1 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O43242 O75832 P0CG47 P0CG48 P11802 P17980 P20618 P24385 P25786 P25787 P25788 P25789 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P49841 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 Q06323 Q13200 Q14997 Q15008 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9UL46 Q9UNM6	BCL1 C7orf76 CCND1 CDK4 DSS1 GSK3B HC2 HC3 HC8 HC9 HSPC IFI5111 KIAA0072 KIAA0077 KIAA0107 LMP10 LMP2 LMP7 LMPX LMPY MB1 MCB1 MECL1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PRAD1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	Catenin beta-1 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 2A G1/S-specific cyclin-D1 G2/mitotic-specific cyclin-B1 Hepatocyte growth factor receptor Lymphoid enhancer-binding factor 1 Serine/threonine-protein kinase PLK1 T-box transcription factor TBX2 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7	P08581 P14635 P24385 P24941 P35222 P36402 P38936 P42771 P53350 Q13207 Q9HCS4 Q9NQB0 Q9UJU2	BCL1 CAP20 CCNB CCNB1 CCND1 CDK2 CDKN1 CDKN1A CDKN2 CDKN2A CIP1 CTNNB CTNNB1 LEF1 MDA6 MET MTS1 PIC1 PLK PLK1 PRAD1 SDI1 TBX2 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 WAF1
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 1C G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Retinoblastoma-associated protein Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3	O00716 O96020 P06400 P11802 P24385 P24864 P24941 P30279 P30281 P38936 P46527 P49918 Q00534 Q01094 Q14186 Q14188 Q14209	BCL1 CAP20 CCND1 CCND2 CCND3 CCNE CCNE1 CCNE2 CDK2 CDK4 CDK6 CDKN1 CDKN1A CDKN1B CDKN1C CDKN2 CDKN6 CIP1 DP1 DP2 E2F1 E2F2 E2F3 KIAA0075 KIP1 KIP2 MDA6 PIC1 PRAD1 RB1 RBBP3 SDI1 TFDP1 TFDP2 WAF1 p27
Drug-mediated inhibition of CDK4/CDK6 activity	Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3	P11802 P24385 P30279 P30281 Q00534	BCL1 CCND1 CCND2 CCND3 CDK4 CDK6 CDKN6 PRAD1
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 C-type lectin domain family 7 member A Caspase recruitment domain-containing protein 11 Caspase recruitment domain-containing protein 9 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C delta type S-phase kinase-associated protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O75832 O95999 P0CG47 P0CG48 P16885 P17980 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43405 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 Q04206 Q05655 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q15750 Q16401 Q8N5C8 Q8TAA3 Q92530 Q99436 Q99460 Q9BXL7 Q9BXN2 Q9H257 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BGR BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARD9 CARMA1 CDC34 CHUK CIPER CLAP CLEC7A CLECSF12 CROC1 CUL1 DECTIN1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MB1 MCB1 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 PKCD PLCG2 POH1 PRKCD PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 RELA RING10 RING12 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 SYK TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 X Y Y2 Z
E3 ubiquitin ligases ubiquitinate target proteins	B-cell lymphoma/leukemia 10 DNA-dependent protein kinase catalytic subunit Derlin-1 E3 ubiquitin-protein ligase BRE1A E3 ubiquitin-protein ligase BRE1B E3 ubiquitin-protein ligase RAD18 E3 ubiquitin-protein ligase RNF144A E3 ubiquitin-protein ligase RNF152 E3 ubiquitin-protein ligase RNF181 E3 ubiquitin-protein ligase SHPRH E3 ubiquitin-protein ligase TM129 HLA class I histocompatibility antigen, A alpha chain Helicase-like transcription factor Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O MHC Class I antigen (B60) (Fragment) Parafibromin Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisome assembly protein 12 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Polyubiquitin-B Polyubiquitin-C Proliferating cell nuclear antigen RNA polymerase II-associated factor 1 homolog RNA polymerase-associated protein CTR9 homolog RNA polymerase-associated protein LEO1 RNA polymerase-associated protein RTF1 homolog Ras-related GTP-binding protein A Selenoprotein S Superkiller complex protein 8 Transitional endoplasmic reticulum ATPase Ubiquitin-conjugating enzyme E2 A Ubiquitin-conjugating enzyme E2 B Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 J2 Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Unique short US11 glycoprotein WW domain-containing adapter protein with coiled-coil	A0AVI4 O00623 O60683 O60814 O75150 O75381 O95999 P04439 P06899 P09727 P0CG47 P0CG48 P12004 P23527 P28328 P33778 P49459 P50876 P51668 P51965 P55072 P58876 P61077 P61088 P62807 P62837 P62979 P62987 P63146 P68036 P78527 Q14527 Q149N8 Q15819 Q5VTR2 Q6P1J9 Q6PD62 Q7L523 Q8N2K1 Q8N7H5 Q8N8N0 Q8WVC0 Q92541 Q92968 Q93079 Q96A08 Q99877 Q99879 Q99880 Q9BQE4 Q9BTA9 Q9BUN8 Q9GZS3 Q9MY60 Q9NS91 Q9P0P0	BCL10 BLU BRE1A BRE1B C1orf28 CDC73 CIPER CLAP CTR9 DER1 DERL1 H2BC1 H2BC10 H2BC11 H2BC12 H2BC13 H2BC14 H2BC15 H2BC17 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFR H2BFT HEL-220 HEL-S-70 HIP116A HIRIP1 HIRIP2 HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HLA-A HLA-B HLAA HLTF HRPT2 HYRC HYRC1 KIAA0155 KIAA0161 KIAA0252 KIAA0661 KIAA1844 KIAA2023 LEO1 MMS2 NCUBE2 PAF1 PAF3 PCNA PD2 PEX10 PEX12 PEX13 PEX14 PEX2 PMP3 PMP35 PRKDC PUBC1 PXMP3 RAD18 RAD6A RAD6B RDL RNF144 RNF144A RNF152 RNF181 RNF20 RNF40 RNF69 RNF72 RNF73 RNF80 RPS27A RRAGA RTF1 SELENOS SELS SFT SH2BP1 SHPRH SKIC8 SMARCA3 SNF2L3 TMEM129 TSH2B UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCE7 UBCE7IP4 UBCEP1 UBCEP2 UBCH1 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBCH6 UBCH7 UBE2A UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2J2 UBE2L3 UBE2N UBE2V2 UEV2 US11 VCP VIMP WAC WDR61 ZBU1
Downstream TCR signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 Caspase recruitment domain-containing protein 11 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C theta type Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell receptor-associated transmembrane adapter 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase Lck Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A0A6YYK7 A5LHX3 O00231 O00232 O00233 O00459 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O43353 O75832 O95999 P01730 P01733 P01737 P01848 P01850 P01903 P01906 P01909 P01911 P01920 P04234 P04435 P04437 P04440 P05538 P06239 P07766 P09693 P0CG47 P0CG48 P13762 P17980 P19838 P20036 P20618 P25786 P25787 P25788 P25789 P25963 P27986 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P42336 P42338 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60484 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 P79483 Q04206 Q04759 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q16401 Q30154 Q6PIZ9 Q8TAA3 Q92530 Q92835 Q99436 Q99460 Q9BXL7 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARDIAK CARMA1 CD3D CD3E CD3G CD4 CDC34 CHUK CIPER CLAP CROC1 CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 GRB1 HC2 HC3 HC8 HC9 HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLASB HSPC IFI5111 IKBA IKBKB IKBKG IKKA IKKB INPP5D KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LCK LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MAP3K7IP2 MB1 MCB1 MECL1 MIP224 MLT MMAC1 MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 POH1 PRKCQ PRKCT PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTEN PUBC1 RELA RICK RING10 RING12 RIP2 RIPK2 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SHIP SHIP1 SKP1 SKP1A SUG1 SUG2 T3D T3E T3G TAB2 TAK1 TBP1 TBP7 TCEB1L TCF16 TCRA TCRBV12S3 TCRBV8S1 TCRIM TEP1 TRAC TRAF6 TRAP2 TRAT1 TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 X Y Y2 Z
FCERI mediated NF-kB activation	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell lymphoma/leukemia 10 Caspase recruitment domain-containing protein 11 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C theta type RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 2 RAS guanyl-releasing protein 4 S-phase kinase-associated protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Transcription factor p65 Tyrosine-protein kinase Lyn UGa8H (Fragment) Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 R1 Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 A5LHX3 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O15530 O43242 O43318 O75832 O95267 O95999 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0CG47 P0CG48 P0DOY2 P0DOY3 P17980 P19838 P20618 P23083 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49427 P49720 P49721 P51665 P51668 P55036 P60896 P60900 P61088 P61289 P62191 P62195 P62333 P62837 P62979 P62987 P63208 P80748 Q04206 Q04759 Q06323 Q13200 Q13404 Q13616 Q14997 Q15008 Q15750 Q16401 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q7LDG7 Q8N5C8 Q8TAA3 Q8TDF6 Q92530 Q99436 Q99460 Q9BXL7 Q9NYJ8 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y4K3 Q9Y6K9	BCL10 BLU BTRC BTRCP BTRCP2 C7orf76 CARD11 CARMA1 CDC25L CDC34 CHUK CIPER CLAP CROC1 CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IKBA IKBKB IKBKG IKKA IKKB JTK8 KIAA0072 KIAA0077 KIAA0107 KIAA0696 KIAA0733 LMP10 LMP2 LMP7 LMPX LMPY LYN MAD3 MALT1 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MB1 MCB1 MCG7 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NU OCP2 PDK1 PDPK1 PFAAP4 POH1 PRKCQ PRKCT PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PUBC1 RASGRP RASGRP1 RASGRP2 RASGRP4 RELA RING10 RING12 RNF85 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TAB1 TAB2 TAB3 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBCEP1 UBCEP2 UBCH3 UBCH4 UBCH5 UBCH5A UBCH5B UBE2D1 UBE2D2 UBE2N UBE2R1 UBE2V UBE2V1 UEV1 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 X Y Y2 Z
Activation of NF-kappaB in B cells	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell lymphoma/leukemia 10 Caspase recruitment domain-containing protein 11 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor epsilon Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha-type 8 Proteasome subunit beta type-10 Proteasome subunit beta type-11 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Protein kinase C beta type Proto-oncogene c-Rel S-phase kinase-associated protein 1 Transcription factor p65 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A5LHX3 O00221 O00231 O00232 O00233 O00487 O14818 O14920 O15111 O43242 O43318 O75832 O95999 P05771 P0CG47 P0CG48 P17980 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P28062 P28065 P28066 P28070 P28072 P28074 P35998 P40306 P43686 P48556 P49720 P49721 P51665 P55036 P60896 P60900 P61289 P62191 P62195 P62333 P62979 P62987 P63208 Q04206 Q04864 Q06323 Q13200 Q13616 Q14997 Q15008 Q15653 Q16401 Q8TAA3 Q92530 Q99436 Q99460 Q9BXL7 Q9UDY8 Q9UKB1 Q9UL46 Q9UNM6 Q9Y297 Q9Y6K9	BCL10 BTRC BTRCP BTRCP2 C7orf76 CARD11 CARMA1 CHUK CIPER CLAP CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 HC2 HC3 HC8 HC9 HSPC IFI5111 IKBA IKBB IKBE IKBKB IKBKG IKKA IKKB KIAA0072 KIAA0077 KIAA0107 KIAA0696 LMP10 LMP2 LMP7 LMPX LMPY MAD3 MALT1 MAP3K7 MB1 MCB1 MECL1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NFKBIB NFKBIE NU OCP2 PFAAP4 PKCB POH1 PRKCB PRKCB1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA7L PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB5i PSMB6 PSMB6i PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 REL RELA RING10 RING12 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAP2 TRIP9 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Y2 Z
Activation of BIM and translocation to mitochondria	Bcl-2-like protein 11 Dynein light chain 1, cytoplasmic Mitogen-activated protein kinase 8	O43521 P45983 P63167	BCL2L11 BIM DLC1 DNCL1 DNCLC1 DYNLL1 HDLC1 JNK1 MAPK8 PRKM8 SAPK1 SAPK1C
NOTCH1 Intracellular Domain Regulates Transcription	CREB-binding protein Cullin-1 Cyclin-C Cyclin-dependent kinase 8 E3 ubiquitin-protein ligase RBX1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Hairy/enhancer-of-split related with YRPW motif-like protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Hypoxia-inducible factor 1-alpha Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Myc proto-oncogene protein Neurobeachin Neurogenic locus notch homolog protein 1 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Polyubiquitin-B Polyubiquitin-C Recombining binding protein suppressor of hairless S-phase kinase-associated protein 1 SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Transducin-like enhancer protein 1 Transducin-like enhancer protein 2 Transducin-like enhancer protein 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15379 O60907 O75376 P01106 P0CG47 P0CG48 P24863 P46531 P49336 P56524 P62877 P62979 P62987 P63208 Q04724 Q04725 Q04727 Q06330 Q09472 Q13495 Q13547 Q13573 Q13616 Q14469 Q16665 Q5TA89 Q8IZL2 Q8NFP9 Q8WUI4 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96DB2 Q96JK9 Q9BY41 Q9BZK7 Q9NQ87 Q9UBN7 Q9UBP5 Q9UKV0 Q9UQL6 Q9Y5J3 Q9Y618	BCL8B BHLHB31 BHLHB32 BHLHB33 BHLHB38 BHLHB39 BHLHE39 BHLHE78 CBP CCNC CDK8 CG1 CHF1 CHF2 CREBBP CTG26 CUL1 CXorf6 EMC19 EP300 GCN5 GCN5L2 GRG4 GRL HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HEYL HIF1A HL HRT1 HRT2 HRT3 HRY IGKJRB IGKJRB1 IRA1 KAT2A KAT2B KIAA0200 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1261 KIAA1544 KIAA1816 KIAA1819 LYST2 MAML1 MAML2 MAML3 MAMLD1 MITR MOP1 MYC NBEA NCOR1 NCOR2 NOTCH1 OCP2 P300 PASD8 PCAF RBPJ RBPJK RBPSUH RBX1 RNF75 ROC1 RPD3L1 RPS27A SKIIP SKIP SKP1 SKP1A SNW1 TAN1 TBL1 TBL1X TBL1XR1 TBLR1 TCEB1L TLE1 TLE2 TLE4 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
HCN channels	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4	O60741 Q9P1Z3 Q9UL51 Q9Y3Q4	BCNG1 BCNG2 HCN1 HCN2 HCN3 HCN4 KIAA1535
Opsins	Long-wave-sensitive opsin 1 Medium-wave-sensitive opsin 1 Melanopsin Opsin-3 Opsin-5 RPE-retinal G protein-coupled receptor Rhodopsin Short-wave-sensitive opsin 1 Visual pigment-like receptor peropsin	O14718 P03999 P04000 P04001 P08100 P47804 Q6U736 Q9H1Y3 Q9UHM6	BCP ECPN GCP GPR136 MOP OPN1LW OPN1MW OPN1SW OPN2 OPN3 OPN4 OPN5 PGR12 RCP RGR RHO RRH TMEM13
Beta defensins	Beta-defensin (Fragment) Beta-defensin 103 Beta-defensin 104 Beta-defensin 105 Beta-defensin 106 Beta-defensin 107 Beta-defensin 108B Beta-defensin 110 Beta-defensin 112 Beta-defensin 113 Beta-defensin 114 Beta-defensin 115 Beta-defensin 116 Beta-defensin 119 Beta-defensin 121 Beta-defensin 123 Beta-defensin 124 Beta-defensin 125 Beta-defensin 126 Beta-defensin 127 Beta-defensin 128 Beta-defensin 129 Beta-defensin 130A Beta-defensin 130B Beta-defensin 131A Beta-defensin 132 Beta-defensin 133 Beta-defensin 134 Beta-defensin 135 Beta-defensin 1 C-C chemokine receptor type 2 C-C chemokine receptor type 6 Defensin beta 118 Defensin beta 136 Defensin beta 4A Putative beta-defensin 108A Putative beta-defensin 109B Toll-like receptor 1 Toll-like receptor 2	A8MXU0 O15263 O60603 P0DP73 P0DP74 P41597 P51684 P59861 P60022 P81534 Q15399 Q30KP8 Q30KP9 Q30KQ1 Q30KQ3 Q30KQ4 Q30KQ5 Q30KQ6 Q30KQ7 Q30KQ8 Q30KQ9 Q30KR1 Q4QY38 Q5J5C9 Q7Z7B7 Q7Z7B8 Q8IZN7 Q8N104 Q8N687 Q8N688 Q8N690 Q8NES8 Q8NET1 Q8NG35 Q8WTQ1 Q96PH6 Q9BYW3 Q9H1M3 Q9H1M4	BD1 BD3 BD5 BD6 C20orf63 C20orf73 C20orf8 C20orf87 CCR2 CCR6 CKRL3 CMKBR2 CMKBR6 DEFB1 DEFB10 DEFB102 DEFB103 DEFB103A DEFB103B DEFB104 DEFB104A DEFB104B DEFB105 DEFB105A DEFB105B DEFB106 DEFB106A DEFB106B DEFB107 DEFB107A DEFB107B DEFB108 DEFB108A DEFB108B DEFB108C DEFB108P1 DEFB108P2 DEFB109B DEFB109P1B DEFB11 DEFB110 DEFB111 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB117 DEFB118 DEFB119 DEFB12 DEFB120 DEFB121 DEFB123 DEFB124 DEFB125 DEFB126 DEFB127 DEFB128 DEFB129 DEFB13 DEFB130 DEFB130A DEFB130B DEFB131 DEFB131A DEFB132 DEFB133 DEFB134 DEFB135 DEFB136 DEFB14 DEFB15 DEFB16 DEFB18 DEFB19 DEFB2 DEFB20 DEFB21 DEFB23 DEFB24 DEFB25 DEFB26 DEFB27 DEFB28 DEFB29 DEFB3 DEFB30 DEFB31 DEFB32 DEFB4 DEFB4A DEFB4B DEFB5 DEFB6 DEFB7 DEFB8 ESC42 GPR29 HBD1 KIAA0012 STRL22 TIL4 TLR1 TLR2
Defensins	Beta-defensin (Fragment) Beta-defensin 103 Beta-defensin 104 Beta-defensin 105 Beta-defensin 106 Beta-defensin 107 Beta-defensin 108B Beta-defensin 110 Beta-defensin 112 Beta-defensin 113 Beta-defensin 114 Beta-defensin 115 Beta-defensin 116 Beta-defensin 119 Beta-defensin 121 Beta-defensin 123 Beta-defensin 124 Beta-defensin 125 Beta-defensin 126 Beta-defensin 127 Beta-defensin 128 Beta-defensin 129 Beta-defensin 130A Beta-defensin 130B Beta-defensin 131A Beta-defensin 132 Beta-defensin 133 Beta-defensin 134 Beta-defensin 135 Beta-defensin 1 Defensin alpha 4 Defensin alpha 5 Defensin beta 118 Defensin beta 136 Defensin beta 4A Defensin-6 Neutrophil defensin 1 Neutrophil defensin 3	O15263 P0DP73 P0DP74 P12838 P59665 P59666 P59861 P60022 P81534 Q01523 Q01524 Q30KP8 Q30KP9 Q30KQ1 Q30KQ3 Q30KQ4 Q30KQ5 Q30KQ6 Q30KQ7 Q30KQ8 Q30KQ9 Q4QY38 Q5J5C9 Q7Z7B7 Q7Z7B8 Q8IZN7 Q8N104 Q8N687 Q8N688 Q8N690 Q8NES8 Q8NET1 Q8NG35 Q8WTQ1 Q96PH6 Q9BYW3 Q9H1M3 Q9H1M4	BD1 BD3 BD5 BD6 C20orf63 C20orf73 C20orf8 C20orf87 DEF1 DEF3 DEF4 DEF5 DEF6 DEFA1 DEFA1B DEFA2 DEFA3 DEFA4 DEFA5 DEFA6 DEFB1 DEFB10 DEFB102 DEFB103 DEFB103A DEFB103B DEFB104 DEFB104A DEFB104B DEFB105 DEFB105A DEFB105B DEFB106 DEFB106A DEFB106B DEFB107 DEFB107A DEFB107B DEFB108 DEFB108B DEFB11 DEFB110 DEFB111 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB117 DEFB118 DEFB119 DEFB12 DEFB120 DEFB121 DEFB123 DEFB124 DEFB125 DEFB126 DEFB127 DEFB128 DEFB129 DEFB13 DEFB130 DEFB130A DEFB130B DEFB131 DEFB131A DEFB132 DEFB133 DEFB134 DEFB135 DEFB136 DEFB14 DEFB15 DEFB16 DEFB18 DEFB19 DEFB2 DEFB20 DEFB21 DEFB23 DEFB24 DEFB25 DEFB26 DEFB27 DEFB28 DEFB29 DEFB3 DEFB30 DEFB31 DEFB32 DEFB4 DEFB4A DEFB4B DEFB5 DEFB6 DEFB7 DEFB8 ESC42 HBD1 MRS
Dectin-2 family	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 C-type lectin domain family 10 member A C-type lectin domain family 4 member A C-type lectin domain family 4 member C C-type lectin domain family 4 member D C-type lectin domain family 4 member E C-type lectin domain family 6 member A Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Genome polyprotein High affinity immunoglobulin epsilon receptor subunit gamma Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1 Truncated surface protein Truncated surface protein Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK	P03375 P03377 P03378 P04578 P04579 P04580 P04581 P04582 P04583 P04624 P05877 P05878 P05879 P05880 P05881 P05882 P06241 P07948 P12487 P12488 P12489 P12490 P12491 P15941 P16885 P18799 P19549 P19550 P19551 P20871 P20888 P30273 P31819 P31872 P35961 P43405 P98088 Q02505 Q02817 Q5SSG8 Q685J3 Q6EIG7 Q6W4X9 Q70626 Q7Z5P9 Q8IUN9 Q8N307 Q8N387 Q8TAX7 Q8WTT0 Q8WXI7 Q8WXI8 Q96DR8 Q99102 Q99IB8 Q9H195 Q9H3R2 Q9HC84 Q9UKN1 Q9ULY5 Q9UMR7	BDCA2 C6orf205 CA125 CLEC10A CLEC4A CLEC4C CLEC4D CLEC4E CLEC6A CLECSF10 CLECSF11 CLECSF13 CLECSF14 CLECSF6 CLECSF7 CLECSF8 CLECSF9 DCIR DECTIN2 DLEC DRCC1 FCER1G FYN HECL HML JTK8 KIAA1359 LLIR LYN MCL MG2 MINCLE MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 PLCG2 PUM RECC SBEM SMUC SYK env
Activated NTRK2 signals through CDK5	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor TIAM1	P23560 P63000 Q00535 Q13009 Q15078 Q16620	BDNF CDK5 CDK5R CDK5R1 CDKN5 NCK5A NTRK2 PSSALRE RAC1 TC25 TIAM1 TRKB
MECP2 regulates transcription of neuronal ligands	Brain-derived neurotrophic factor Corticoliberin Delta-like protein 1 Histone deacetylase 1 Paired amphipathic helix protein Sin3a Somatostatin	O00548 P06850 P23560 P61278 Q13547 Q96ST3	BDNF CRH DLL1 HDAC1 RPD3L1 SIN3A SST
NTRK2 activates RAC1	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Dedicator of cytokinesis protein 3 Ras-related C3 botulinum toxin substrate 1	P23560 P63000 Q16620 Q8IZD9	BDNF DOCK3 KIAA0299 MOCA NTRK2 RAC1 TC25 TRKB
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Neurotrophin-4 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43559 P01111 P01112 P23560 P34130 Q06124 Q07889 Q16620 Q8WU20	BDNF FRS2 FRS3 HRAS HRAS1 NRAS NTF4 NTF5 NTRK2 PTP2C PTPN11 SHPTP2 SOS1 TRKB
Activated NTRK2 signals through PI3K	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor GRB2-associated-binding protein 1 Neurotrophin-4 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	P23560 P27986 P34130 P42336 Q13480 Q16620	BDNF GAB1 GRB1 NTF4 NTF5 NTRK2 PIK3CA PIK3R1 TRKB
Activated NTRK2 signals through FYN	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Glutamate receptor ionotropic, NMDA 2B Proto-oncogene tyrosine-protein kinase Src	P12931 P23560 Q13224 Q16620	BDNF GRIN2B NMDAR2B NTRK2 SRC SRC1 TRKB

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