GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1601 - 1625** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼
Repression of WNT target genes	C-terminal-binding protein 1 C-terminal-binding protein 2 Histone deacetylase 1 Lymphoid enhancer-binding factor 1 TLE family member 5 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7 Transducin-like enhancer protein 1 Transducin-like enhancer protein 2 Transducin-like enhancer protein 3 Transducin-like enhancer protein 4	P36402 P56545 Q04724 Q04725 Q04726 Q04727 Q08117 Q13363 Q13547 Q9HCS4 Q9NQB0 Q9UJU2	AES CTBP CTBP1 CTBP2 GRG GRG4 GRG5 HDAC1 KIAA1261 KIAA1547 LEF1 RPD3L1 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 TLE1 TLE2 TLE3 TLE4 TLE5
PKMTs methylate histone lysines	Actin-histidine N-methyltransferase Activating transcription factor 7-interacting protein 1 Histone H3.1 Histone H3.2 Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase 2A Histone-lysine N-methyltransferase 2B Histone-lysine N-methyltransferase 2C Histone-lysine N-methyltransferase 2D Histone-lysine N-methyltransferase ASH1L Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase KMT5B Histone-lysine N-methyltransferase KMT5C Histone-lysine N-methyltransferase MECOM Histone-lysine N-methyltransferase NSD2 Histone-lysine N-methyltransferase NSD3 Histone-lysine N-methyltransferase PRDM16 Histone-lysine N-methyltransferase PRDM9 Histone-lysine N-methyltransferase SETD1A Histone-lysine N-methyltransferase SETD1B Histone-lysine N-methyltransferase SETD2 Histone-lysine N-methyltransferase SETD7 Histone-lysine N-methyltransferase SETDB1 Histone-lysine N-methyltransferase SETDB2 Histone-lysine N-methyltransferase SMYD3 Histone-lysine N-methyltransferase SUV39H1 Histone-lysine N-methyltransferase SUV39H2 Histone-lysine N-methyltransferase, H3 lysine-36 specific Histone-lysine N-methyltransferase, H3 lysine-79 specific N-lysine methyltransferase KMT5A N-lysine methyltransferase SETD6 N-lysine methyltransferase SMYD2 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Polycomb protein EED Polycomb protein SUZ12 Protein dpy-30 homolog Retinoblastoma-binding protein 5 Set1/Ash2 histone methyltransferase complex subunit ASH2 Transcription factor p65 WD repeat-containing protein 5 Zinc finger protein AEBP2	O14686 O15047 O43463 O75530 O96028 P19838 P61964 P62805 P68431 Q00653 Q03112 Q03164 Q04206 Q09028 Q15022 Q15047 Q15291 Q15910 Q16576 Q4FZB7 Q6VMQ6 Q6ZN18 Q71DI3 Q86TU7 Q86Y97 Q8NEZ4 Q8TBK2 Q8TEK3 Q8WTS6 Q96KQ7 Q96L73 Q96T68 Q9BYW2 Q9BZ95 Q9C005 Q9H5I1 Q9H7B4 Q9H9B1 Q9HAZ2 Q9NQR1 Q9NQV7 Q9NR48 Q9NRG4 Q9UBL3 Q9UMN6 Q9UPS6	AEBP2 ALL1 ALR ARA267 ASH1L ASH2L ASH2L1 ATF7IP BAT8 BIG3 C13orf4 C14orf154 C6orf30 CHET9 CLLD8 CXXC7 DOT1L DPY30 EED EHMT1 EHMT2 ESET EUHMTASE1 EVI1 EZH2 G9A GLP H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HALR HIF1 HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST4H4 HRX HRX2 HTRX HYPB JJAZ1 KIAA0067 KIAA0160 KIAA0304 KIAA0339 KIAA1076 KIAA1090 KIAA1420 KIAA1506 KIAA1675 KIAA1717 KIAA1732 KIAA1814 KIAA1876 KMT1A KMT1B KMT1C KMT1D KMT1E KMT1F KMT2A KMT2B KMT2C KMT2D KMT2F KMT2G KMT2H KMT3A KMT3B KMT3C KMT4 KMT5A KMT5B KMT5C KMT6 KMT7 LYT10 MCAF MCAF1 MDS1 MECOM MEL1 MLL MLL1 MLL2 MLL3 MLL4 MMSET NFKB1 NFKB2 NFKB3 NG36 NSD1 NSD2 NSD3 PFM13 PFM6 PRDM16 PRDM3 PRDM9 PRSET7 RBAP46 RBAP48 RBBP4 RBBP5 RBBP7 RBQ3 RELA SET07 SET1 SET1A SET1B SET2 SET7 SET8 SET9 SETD1A SETD1B SETD2 SETD3 SETD6 SETD7 SETD8 SETDB1 SETDB2 SMYD2 SMYD3 SUV39H SUV39H1 SUV39H2 SUV420H1 SUV420H2 SUZ12 TRX1 TRX2 TRX5 WBP7 WDR5 WHSC1 WHSC1L1 ZMYND1 ZNFN3A1
PRC2 methylates histones and DNA	DNA (cytosine-5)-methyltransferase 1 DNA (cytosine-5)-methyltransferase 3A DNA (cytosine-5)-methyltransferase 3B Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Metal-response element-binding transcription factor 2 PHD finger protein 19 PHD finger protein 1 Polycomb protein EED Polycomb protein SUZ12 Protein Jumonji Zinc finger protein AEBP2	O43189 O60814 O75530 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P26358 P33778 P57053 P58876 P62805 P62807 P68431 P84243 Q09028 Q15022 Q15910 Q16576 Q16777 Q16778 Q5T6S3 Q6FI13 Q6ZN18 Q71DI3 Q71UI9 Q8N257 Q92833 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9UBC3 Q9Y483 Q9Y6K1	AEBP2 AIM CHET9 CXXC9 DNMT DNMT1 DNMT3A DNMT3B EED EZH2 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 JARID2 JJAZ1 JMJ KIAA0160 KMT6 MTF2 PCL1 PCL2 PCL3 PHF1 PHF19 RBAP46 RBAP48 RBBP4 RBBP7 SUZ12 TSH2B
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA)	Band 3 anion transport protein	P02730	AE1 DI EPB3 SLC4A1
Erythrocytes take up oxygen and release carbon dioxide	Ammonium transporter Rh type A Aquaporin-1 Band 3 anion transport protein Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 4 Hemoglobin subunit alpha Hemoglobin subunit beta	P00915 P00918 P02730 P22748 P29972 P68871 P69905 Q02094	AE1 AQP1 CA1 CA2 CA4 CHIP28 DI EPB3 HBA1 HBA2 HBB RH50 RHAG SLC4A1
Erythrocytes take up carbon dioxide and release oxygen	Ammonium transporter Rh type A Aquaporin-1 Band 3 anion transport protein Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 4 Cytochrome b5 reductase 4 Hemoglobin subunit alpha Hemoglobin subunit beta NADH-cytochrome b5 reductase 1 NADH-cytochrome b5 reductase 2 NADH-cytochrome b5 reductase-like	P00915 P00918 P02730 P22748 P29972 P68871 P69905 Q02094 Q6BCY4 Q6IPT4 Q7L1T6 Q9UHQ9	AE1 AQP1 CA1 CA2 CA4 CHIP28 CYB5R1 CYB5R2 CYB5R4 CYB5RL DI EPB3 HBA1 HBA2 HBB NCB5OR NQO3A2 RH50 RHAG SLC4A1
Bicarbonate transporters	Adenosylhomocysteinase 3 Anion exchange protein 2 Anion exchange protein 3 Anion exchange protein 4 Band 3 anion transport protein Electrogenic sodium bicarbonate cotransporter 1 Electrogenic sodium bicarbonate cotransporter 4 Electroneutral sodium bicarbonate exchanger 1 Sodium bicarbonate cotransporter 3 Sodium-driven chloride bicarbonate exchanger	P02730 P04920 P48751 Q2Y0W8 Q6U841 Q96HN2 Q96Q91 Q9BY07 Q9Y6M7 Q9Y6R1	AE1 AE2 AE3 AE4 AHCYL2 BT DI EPB3 EPB3L1 HKB3 KIAA0739 KIAA0828 MPB3L NBC NBC1 NBC2 NBC2B NBC3 NBC4 NBCE1 NBCN2 NBCn1 NCBE NDCBE1 SBC2 SBC5 SLC4A1 SLC4A10 SLC4A2 SLC4A3 SLC4A4 SLC4A5 SLC4A6 SLC4A7 SLC4A8 SLC4A9
Mitochondrial iron-sulfur cluster biogenesis	Adrenodoxin, mitochondrial Ferredoxin-2, mitochondrial Frataxin, mitochondrial Glutaredoxin-related protein 5, mitochondrial Iron-sulfur cluster assembly 1 homolog, mitochondrial Iron-sulfur cluster assembly 2 homolog, mitochondrial Iron-sulfur cluster co-chaperone protein HscB LYR motif-containing protein 4 Mitoferrin-1 Mitoferrin-2	P10109 Q16595 Q6P4F2 Q86SX6 Q86U28 Q8IWL3 Q96A46 Q9BUE6 Q9HD34 Q9NYZ2	ADX C14orf87 C6orf149 DNAJC20 FDX1 FDX1L FDX2 FRDA FXN GLRX5 HBLD1 HBLD2 HSC20 HSCB ISCA1 ISCA2 ISD11 LYRM4 MFRN MFRN2 MSCP SLC25A28 SLC25A37 X25
Protein lipoylation	Acyl carrier protein, mitochondrial Adrenodoxin, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Lipoyl amidotransferase LIPT1, mitochondrial Lipoyl synthase, mitochondrial NFU1 iron-sulfur cluster scaffold homolog, mitochondrial Octanoyl-[acyl-carrier-protein]	A6NK58 O14561 O43766 P10109 P10515 P11182 P23434 P36957 Q9UMS0 Q9Y234	ADX BCATE2 BCKDHE2 DBT DLAT DLST DLTA DLTS FDX1 GCSH HIRIP5 LAS LIAS LIPT1 LIPT2 NDUFAB1 NFU1
Electron transport from NADPH to Ferredoxin	Adrenodoxin, mitochondrial Ferredoxin-2, mitochondrial NADPH	P10109 P22570 Q6P4F2	ADX ADXR FDX1 FDX1L FDX2 FDXR
Defective CYP11A1 causes AICSR	Adrenodoxin, mitochondrial Cholesterol side-chain cleavage enzyme, mitochondrial Ferredoxin-2, mitochondrial NADPH	P05108 P10109 P22570 Q6P4F2	ADX ADXR CYP11A CYP11A1 FDX1 FDX1L FDX2 FDXR
Pregnenolone biosynthesis	Adrenodoxin, mitochondrial Aldo-keto reductase family 1 member B1 Cholesterol side-chain cleavage enzyme, mitochondrial Ferredoxin-2, mitochondrial NADPH Peripheral-type benzodiazepine receptor-associated protein 1 STARD3 N-terminal-like protein StAR-related lipid transfer protein 3 StAR-related lipid transfer protein 4 StAR-related lipid transfer protein 6 Steroidogenic acute regulatory protein, mitochondrial Translocator protein	O95153 O95772 P05108 P10109 P15121 P22570 P30536 P49675 P59095 Q14849 Q6P4F2 Q96DR4	ADX ADXR AKR1B1 ALDR1 ALR2 BZRAP1 BZRP CAB1 CYP11A CYP11A1 FDX1 FDX1L FDX2 FDXR KIAA0612 MBR MENTHO MLN64 RBP1 RIMBP1 STAR STARD1 STARD3 STARD3NL STARD4 STARD6 TSPO TSPOAP1
Endogenous sterols	24-hydroxycholesterol 7-alpha-hydroxylase Adrenodoxin, mitochondrial Aromatase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Bile acid receptor Cholesterol 24-hydroxylase Cholesterol side-chain cleavage enzyme, mitochondrial Cytochrome P450 11B1, mitochondrial Cytochrome P450 11B2, mitochondrial Cytochrome P450 1B1 Cytochrome P450 4V2 Cytochrome P450 7A1 Cytochrome P450 7B1 Ferredoxin-2, mitochondrial Lanosterol 14-alpha demethylase NADPH Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Pro-opiomelanocortin Retinoic acid receptor RXR-alpha Steroid 21-hydroxylase Sterol 26-hydroxylase, mitochondrial	A9YTQ3 O75881 P01189 P05108 P08686 P10109 P11511 P15538 P19099 P19793 P22570 P22680 P27540 P35869 Q02318 Q15596 Q15788 Q16678 Q16850 Q6P4F2 Q6ZWL3 Q96RI1 Q9HBZ2 Q9NYL5 Q9Y6A2	ADX ADXR AHR AHRR ARNT ARNT2 ARO1 BAR BHLHE1 BHLHE2 BHLHE74 BHLHE75 BHLHE76 BHLHE77 CYAR CYP11A CYP11A1 CYP11B1 CYP11B2 CYP19 CYP19A1 CYP1B1 CYP21 CYP21A2 CYP21B CYP27 CYP27A1 CYP39A1 CYP46 CYP46A1 CYP4V2 CYP51 CYP51A1 CYP7 CYP7A1 CYP7B1 FDX1 FDX1L FDX2 FDXR FXR HRR1 KIAA0307 KIAA1234 NCOA1 NCOA2 NR1H4 NR2B1 POMC RIP14 RXRA S11BH SRC1 SRC2 TIF2
Signaling by BRAF and RAF1 fusions	14-3-3 protein beta/alpha A-kinase anchor protein 9 AP-3 complex subunit beta-1 Acylglycerol kinase, mitochondrial Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Angiogenic factor with G patch and FHA domains 1 Bcl-2-like protein 11 Beta-arrestin-1 Beta-arrestin-2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epithelial splicing regulatory protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas H(+)/Cl(-) exchange transporter 6 Integrin alpha-IIb Integrin beta-3 KH domain-containing RNA-binding protein QKI Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 Lysine-specific demethylase 7A MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin phosphatase Rho-interacting protein Phosphatidylethanolamine-binding protein 1 Prelamin-A/C Protein FAM114A2 Protein FAM131B Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase RNA-binding protein FXR1 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Staphylococcal nuclease domain-containing protein 1 Talin-1 Terminal nucleotidyltransferase 4A Trafficking kinesin-binding protein 1 Transcription intermediary factor 1-alpha Type-1 angiotensin II receptor-associated protein Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 UPF0606 protein KIAA1549 Ubiquitin-like modifier-activating enzyme ATG7 Vinculin Zinc finger CCCH-type antiviral protein 1 von Willebrand factor	O00203 O15164 O43252 O43521 O60674 O95352 P01111 P01112 P02545 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P51114 P51797 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q53H12 Q5XG87 Q6NXG1 Q6RW13 Q6VAB6 Q6WCQ1 Q6ZMT4 Q7KZF4 Q7Z2W4 Q7Z5R6 Q86XD5 Q8IVT5 Q8N302 Q8WXI2 Q969H4 Q96PU8 Q99996 Q9HCM3 Q9NRY5 Q9UPV9 Q9UQM7 Q9Y490	ADTB3A AGGF1 AGK AGTRAP AKAP350 AKAP450 AKAP9 AP3B1 APBB1IP APG7L ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 ATG7 ATPSK1 ATRAP BCL2L11 BIM BRAF BRAF1 C5orf3 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CLCN6 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 ESRP1 F8VWF FAM114A2 FAM131B FGA FGB FGG FN FN1 FXR1 GP2B GP3A GPATC7 GPATCH7 HKQ HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 JHDM1D KDM7 KDM7A KIAA0046 KIAA0051 KIAA0773 KIAA0803 KIAA0864 KIAA0902 KIAA0968 KIAA1027 KIAA1042 KIAA1549 KIAA1718 KREV1 KSR KSR1 KSR2 LMN1 LMNA MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MPRIP MRIP MULK NRAS OIP106 PAPD7 PAPSS PAPSS1 PBP PEBP PEBP1 PKS PKS2 POLS PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 QKI RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RBM35A RHOIP3 RIAM RNF82 SND1 SRC SRC1 TDRD11 TENT4A TIF1 TIF1A TLN TLN1 TRAK1 TRF4 TRIM24 VCL VG5Q VWF YWHAB ZC3HAV1 ZC3HDC2
Nef mediated downregulation of MHC class I complex cell surface expression	AP-1 complex subunit beta-1 AP-1 complex subunit gamma-1 AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-1 complex subunit sigma-3 Beta-2-microglobulin HLA class I histocompatibility antigen, A alpha chain Phosphofurin acidic cluster sorting protein 1 Protein Nef	O43747 P04439 P04601 P56377 P61769 P61966 Q10567 Q6VY07 Q96PC3 Q9BXS5 Q9Y6Q5	ADTB1 ADTG AP19 AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 B2M BAM22 CLAPB2 CLAPG1 CLAPS1 CLTNM HLA-A HLAA KIAA1175 PACS1 nef
Retrograde neurotrophin signalling	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Beta-nerve growth factor Clathrin heavy chain 1 Clathrin light chain A Dynamin-1 Dynamin-2 Dynamin-3 Dynein axonemal light chain 4 Endophilin-A1 High affinity nerve growth factor receptor	O94973 O95782 O96015 P01138 P04629 P09496 P50570 P53680 P63010 Q00610 Q05193 Q96CW1 Q99962 Q9UQ16	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 CNSA2 DNAL4 DNM DNM1 DNM2 DNM3 DYN2 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0820 KIAA0899 MTC NGF NGFB NTRK1 SH3D2A SH3GL2 TRK TRKA
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Frizzled-2 Frizzled-5 Inactive tyrosine-protein kinase transmembrane receptor ROR1 Protein Wnt-5a Tyrosine-protein kinase transmembrane receptor ROR2	O94973 O95782 P09496 P09497 P41221 P53680 P63010 Q00610 Q01973 Q01974 Q13467 Q14332 Q96CW1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 C2orf31 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTB CLTC CLTCL2 FZD2 FZD5 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0899 NTRKR1 NTRKR2 ROR1 ROR2 WNT5A
Recycling pathway of L1	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Chromosome-associated kinesin KIF4A Chromosome-associated kinesin KIF4B Clathrin heavy chain 1 Clathrin light chain A Dihydropyrimidinase-related protein 2 Dynamin-1 Dynamin-2 Dynamin-3 Endophilin-A1 Ezrin Mitogen-activated protein kinase 1 Moesin Neural cell adhesion molecule L1 Protein numb homolog Radixin Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-4 Ribosomal protein S6 kinase alpha-5 Ribosomal protein S6 kinase alpha-6 Shootin-1	A0MZ66 O75582 O75676 O94973 O95239 O95782 P09496 P15311 P26038 P28482 P32004 P35241 P49757 P50570 P51812 P53680 P63010 Q00610 Q05193 Q15349 Q15418 Q16555 Q2VIQ3 Q96CW1 Q99962 Q9UK32 Q9UQ16	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 C14orf41 CAML1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 CNSA2 CRMP2 DNM DNM1 DNM2 DNM3 DPYSL2 DYN2 ERK2 EZR HIP9 HYPJ ISPK1 KIAA0034 KIAA0109 KIAA0820 KIAA0899 KIAA1598 KIF4 KIF4A KIF4B L1CAM MAPK1 MAPKAPK1A MAPKAPK1B MAPKAPK1C MIC5 MSK1 MSK2 MSN NUMB PRKM1 PRKM2 RDX RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 RSK1 RSK2 RSK3 RSK4 SH3D2A SH3GL2 SHTN1 ULIP2 VIL2
VLDLR internalisation and degradation	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain 1 Clathrin light chain A E3 ubiquitin-protein ligase MYLIP Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Polyubiquitin-B Polyubiquitin-C Proprotein convertase subtilisin/kexin type 9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Very low-density lipoprotein receptor	O94973 O95782 P09496 P0CG47 P0CG48 P53680 P55055 P62979 P62987 P63010 P98155 Q00610 Q13133 Q8NBP7 Q8WY64 Q96CW1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 BZF1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 HIP9 HYPJ IDOL KIAA0034 KIAA0109 KIAA0899 LXRA LXRB MYLIP NARC1 NER NR1H2 NR1H3 PCSK9 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UNR VLDLR
Nef Mediated CD8 Down-regulation	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Protein Nef T-cell surface glycoprotein CD8 beta chain V-type proton ATPase subunit H	O94973 O95782 P04601 P10966 P53680 P63010 Q96CW1 Q9UI12	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ATP6V1H CD8B CD8B1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 HIP9 HYPJ KIAA0109 KIAA0899 nef
Nef Mediated CD4 Down-regulation	ADP-ribosylation factor 1 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Protein Nef T-cell surface glycoprotein CD4 Tyrosine-protein kinase Lck V-type proton ATPase subunit H	O94973 O95782 P01730 P04601 P06239 P53680 P63010 P84077 Q96CW1 Q9UI12	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 ATP6V1H CD4 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 HIP9 HYPJ KIAA0109 KIAA0899 LCK nef
WNT5A-dependent internalization of FZD4	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Beta-arrestin-2 Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Frizzled-4 Protein Wnt-5a Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type Segment polarity protein dishevelled homolog DVL-2	O14641 O94973 O95782 P05129 P05771 P09496 P09497 P17252 P32121 P41221 P53680 P63010 Q00610 Q96CW1 Q9ULV1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARB2 ARR2 ARRB2 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTB CLTC CLTCL2 DVL2 FZD4 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0899 PKCA PKCB PKCG PRKACA PRKCA PRKCB PRKCB1 PRKCG WNT5A
Calmodulin induced events	Beta-adrenergic receptor kinase 1 Calmodulin-1 Protein kinase C alpha type Protein kinase C delta type Protein kinase C gamma type	P05129 P0DP23 P17252 P25098 Q05655	ADRBK1 BARK BARK1 CALM CALM1 CAM CAM1 GRK2 PKCA PKCD PKCG PRKACA PRKCA PRKCD PRKCG
Activation of SMO	Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Brother of CDO Casein kinase I isoform alpha Cell adhesion molecule-related/down-regulated by oncogenes Desert hedgehog protein Dynein regulatory complex subunit 4 EF-hand calcium-binding domain-containing protein 7 EvC complex member EVC Growth arrest-specific protein 1 IQ domain-containing protein E Indian hedgehog protein Kinesin-like protein KIF3A Limbin Protein patched homolog 1 Protein smoothened Sonic hedgehog protein	A8K855 O43323 O95995 P25098 P32121 P48729 P49407 P54826 P57679 Q13635 Q14623 Q15465 Q4KMG0 Q6IPM2 Q86UK5 Q99835 Q9BWV1 Q9Y496	ADRBK1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BARK BARK1 BOC CDO CDON CSNK1A1 DHH DRC4 EFCAB7 EVC EVC2 GAS1 GAS11 GAS8 GRK2 IHH IQCE KIAA1023 KIAA1799 KIF3 KIF3A LBN PTCH PTCH1 SHH SMO SMOH
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P47898 P50406 Q13639	ADRB2RL1 ADRBRL1 HTR1A HTR1B HTR1C HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HTRL

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