GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **576 - 600** of **2074** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism
ADP signalling through P2Y purinoceptor 1	Cytosolic phospholipase A2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Mitogen-activated protein kinase 14 P2Y purinoceptor 1	O14610 O14775 O60262 O95837 P16520 P29992 P30679 P47712 P47900 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q16539 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	CPLA2 CSBP CSBP1 CSBP2 CSPB1 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 MAPK14 MXI2 P2RY1 PLA2G4 PLA2G4A SAPK2A	Homo sapiens (human)
Glucagon-type ligand receptors	Gastric inhibitory polypeptide receptor Gastric inhibitory polypeptide Glucagon receptor Glucagon-like peptide 1 receptor Glucagon-like peptide 2 receptor Growth hormone-releasing hormone receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide Pro-glucagon Secretin receptor Secretin Somatoliberin VIP peptides Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal polypeptide receptor 2	O14610 O14775 O60262 O95838 P01275 P01282 P01286 P09681 P09683 P16520 P18509 P32241 P41586 P41587 P43220 P47871 P47872 P48546 P50150 P50151 P59768 P61952 P62873 P62879 P63092 P63211 P63215 P63218 Q02643 Q5JWF2 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCYAP1 ADCYAP1R1 GCG GCGR GHRF GHRH GHRHR GIP GIPR GLP1R GLP2R GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP SCT SCTR VIP VIP2R VIPR1 VIPR2	Homo sapiens (human)
Prostacyclin signalling through prostacyclin receptor	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Prostacyclin receptor	O14610 O14775 O60262 P16520 P43119 P50150 P50151 P59768 P61952 P62873 P62879 P63092 P63211 P63215 P63218 Q5JWF2 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP PRIPR PTGIR	Homo sapiens (human)
G beta:gamma signalling through CDC42	Cell division control protein 42 homolog Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rho guanine nucleotide exchange factor 6 Serine/threonine-protein kinase PAK 1	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P60953 P61952 P62873 P62879 P63211 P63215 P63218 Q13153 Q15052 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ARHGEF6 CDC42 COOL2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0006 PAK1 PIXA	Homo sapiens (human)
Presynaptic function of Kainate receptors	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Glutamate receptor ionotropic, kainate 3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q00722 Q01970 Q13003 Q9HAV0 Q9NQ66 Q9P2W3 Q9UBI6 Q9UK08	GLUR7 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GRIK3 KIAA0581 PLCB1 PLCB2 PLCB3	Homo sapiens (human)
G beta:gamma signalling through PLC beta	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q00722 Q01970 Q9HAV0 Q9NQ66 Q9P2W3 Q9UBI6 Q9UK08	GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0581 PLCB1 PLCB2 PLCB3	Homo sapiens (human)
G beta:gamma signalling through BTK	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Tyrosine-protein kinase BTK	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q06187 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	AGMX1 ATK BPK BTK GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9	Homo sapiens (human)
Vitamin B5 (pantothenate) metabolism	4'-phosphopantetheine phosphatase Autotaxin Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 Fatty acid synthase L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mitochondrial coenzyme A diphosphatase NUDT8 Mitochondrial coenzyme A transporter SLC25A42 PDZ domain-containing protein 11 Pantetheinase Pantetheine hydrolase VNN2 Sodium-dependent multivitamin transporter Solute carrier family 25 member 16	O14638 O95497 O95498 P16260 P22413 P49327 Q13822 Q5EBL8 Q86VD7 Q8WV74 Q9NRN7 Q9NVE7 Q9Y289	AASDHPPT AIPP1 ATX ENPP1 ENPP2 ENPP3 FAS FASN GDA M6S1 NPPS NUDT8 PANK4 PC1 PDNP1 PDNP2 PDNP3 PDZD11 PDZK11 PISP SLC25A16 SLC25A42 SLC5A6 SMVT VNN1 VNN2	Homo sapiens (human)
TCF dependent signaling in response to WNT	Axin-1 Axin-2 Catenin beta-1 Dickkopf-related protein 1 Dickkopf-related protein 2 Dickkopf-related protein 4 E3 ubiquitin-protein ligase RNF146 Frizzled-1 Frizzled-2 Kremen protein 1 Kremen protein 2 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2 Polyubiquitin-B Polyubiquitin-C Protein Wnt-3a Protein Wnt-4 Protein Wnt-5a Protein Wnt-8a Protein Wnt-8b Protein Wnt-9a Proto-oncogene Wnt-1 Proto-oncogene Wnt-3 Sclerostin Secreted frizzled-related protein 1 Secreted frizzled-related protein 2 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Tyrosine-protein kinase RYK Ubiquitin carboxyl-terminal hydrolase 34 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Wnt inhibitory factor 1	O14640 O14641 O14904 O15169 O75197 O75581 O94907 O95271 P04628 P0CG47 P0CG48 P34925 P35222 P41221 P56703 P56704 P56705 P62979 P62987 Q14332 Q70CQ2 Q8N474 Q8NCW0 Q92997 Q93098 Q96HF1 Q96MU8 Q9BQB4 Q9H1J5 Q9H2K2 Q9NTX7 Q9UBT3 Q9UBU2 Q9UP38 Q9Y2T1 Q9Y5W5	AXIN AXIN1 AXIN2 CTNNB CTNNB1 DKK1 DKK2 DKK4 DVL1 DVL2 DVL3 FRP FRP1 FRP2 FZD1 FZD2 INT1 INT4 JTK5A KIAA0208 KIAA0570 KIAA0729 KREMEN KREMEN1 KREMEN2 KRM1 KRM2 LR3 LRP5 LRP6 LRP7 PARP5A PARP5B PARPL RNF146 RPS27A RYK SARP1 SARP2 SFRP1 SFRP2 SOST TANK2 TIN1 TINF1 TNKL TNKS TNKS1 TNKS2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP34 WIF1 WNT1 WNT14 WNT3 WNT3A WNT4 WNT5A WNT8A WNT8B WNT8D WNT9A	Homo sapiens (human)
WNT mediated activation of DVL	Casein kinase I isoform epsilon Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3	O14640 O14641 O14986 P19784 P49674 P67870 P68400 Q92997	CK2A1 CK2A2 CK2N CSNK1E CSNK2A1 CSNK2A2 CSNK2B DVL1 DVL2 DVL3 G5A KIAA0208 PIP5K1B STM7	Homo sapiens (human)
Disassembly of the destruction complex and recruitment of AXIN to the membrane	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Casein kinase I isoform gamma-2 Catenin beta-1 Caveolin-1 Frizzled-1 Frizzled-2 Frizzled-5 GSK-3-binding protein FRAT2 Glycogen synthase kinase-3 beta Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Protein Wnt-3a Protein Wnt-8a Protein Wnt-8b Proto-oncogene FRAT1 Proto-oncogene Wnt-1 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O14640 O14641 O15169 O75197 O75474 O75581 P04628 P25054 P30153 P30154 P35222 P48729 P49841 P56704 P62714 P67775 P78368 Q03135 Q13362 Q13467 Q14332 Q14738 Q15172 Q15173 Q16537 Q5JTC6 Q92837 Q92997 Q93098 Q9H1J5 Q9UP38	AMER1 APC AXIN AXIN1 C2orf31 CAV CAV1 CK1G2 CSNK1A1 CSNK1G2 CTNNB CTNNB1 DP2.5 DVL1 DVL2 DVL3 FAM123B FRAT1 FRAT2 FZD1 FZD2 FZD5 GSK3B INT1 KIAA0044 KIAA0208 LR3 LRP5 LRP6 LRP7 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WNT1 WNT3A WNT8A WNT8B WNT8D WTX	Homo sapiens (human)
PCP/CE pathway	Disheveled-associated activator of morphogenesis 1 Frizzled-1 Frizzled-3 Frizzled-6 Frizzled-7 Profilin-1 Protein Wnt-11 Protein Wnt-4 Protein Wnt-5a Protein Wnt-5b Proto-oncogene Wnt-1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Ras-related C3 botulinum toxin substrate 3 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Transforming protein RhoA Tyrosine-protein kinase RYK Tyrosine-protein kinase transmembrane receptor ROR2 Vang-like protein 2	O14640 O14641 O60353 O75084 O96014 P04628 P07737 P15153 P34925 P41221 P56705 P60763 P61586 P63000 Q01974 Q92997 Q9H1J7 Q9NPG1 Q9ULK5 Q9UP38 Q9Y4D1	ARH12 ARHA DAAM1 DVL1 DVL2 DVL3 FZD1 FZD3 FZD6 FZD7 INT1 JTK5A KIAA0208 KIAA0666 KIAA1215 NTRKR2 PFN1 RAC1 RAC2 RAC3 RHO12 RHOA ROR2 RYK STB1 TC25 VANGL2 WNT1 WNT11 WNT4 WNT5A WNT5B	Homo sapiens (human)
WNT5:FZD7-mediated leishmania damping	Cytochrome b-245 light chain Frizzled-7 Mitogen-activated protein kinase 8 NADPH oxidase 1 NADPH oxidase activator 1 NADPH oxidase organizer 1 Protein Wnt-5a Ras-related C3 botulinum toxin substrate 1 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Transcription factor Jun	O14640 O14641 O75084 P05412 P13498 P41221 P45983 P63000 Q86UR1 Q8NFA2 Q92997 Q9Y5S8	CYBA DVL1 DVL2 DVL3 FZD7 JNK1 JUN KIAA0208 MAPK8 MOX1 NOH1 NOX1 NOXA1 NOXO1 P41NOX P51NOX PRKM8 RAC1 SAPK1 SAPK1C SH3PXD5 TC25 WNT5A	Homo sapiens (human)
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	CXXC-type zinc finger protein 4 Protein Daple Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3	O14640 O14641 Q92997 Q9H2H0 Q9P219	CCDC88C CXXC4 DAPLE DVL1 DVL2 DVL3 IDAX KIAA0208 KIAA1509	Homo sapiens (human)
Signaling by Hippo	14-3-3 protein beta/alpha 14-3-3 protein epsilon Angiomotin-like protein 1 Angiomotin-like protein 2 Caspase-3 MOB kinase activator 1A MOB kinase activator 1B Nephrocystin-4 Protein KIBRA Protein salvador homolog 1 Segment polarity protein dishevelled homolog DVL-2 Serine/threonine-protein kinase 3 Serine/threonine-protein kinase 4 Serine/threonine-protein kinase LATS1 Serine/threonine-protein kinase LATS2 Tight junction protein ZO-1 Tight junction protein ZO-2 Transcriptional coactivator YAP1 WW domain-containing transcription regulator protein 1	O14641 O75161 O95835 P31946 P42574 P46937 P62258 Q07157 Q13043 Q13188 Q7L9L4 Q8IX03 Q8IY63 Q9GZV5 Q9H4B6 Q9H8S9 Q9NRM7 Q9UDY2 Q9Y2J4	AMOTL1 AMOTL2 C2orf6 CASP3 CPP32 DVL2 KIAA0673 KIAA0869 KIAA0989 KIBRA KPM KRS1 KRS2 LATS1 LATS2 MOB1A MOB1B MOB4A MOB4B MOBK1B MOBKL1A MOBKL1B MST1 MST2 NPHP4 SAV1 STK3 STK4 TAZ TJP1 TJP2 WARTS WW45 WWC1 WWTR1 X104 YAP1 YAP65 YWHAB YWHAE ZO1 ZO2	Homo sapiens (human)
WNT5A-dependent internalization of FZD4	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Beta-arrestin-2 Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Frizzled-4 Protein Wnt-5a Protein kinase C alpha type Protein kinase C beta type Protein kinase C gamma type Segment polarity protein dishevelled homolog DVL-2	O14641 O94973 O95782 P05129 P05771 P09496 P09497 P17252 P32121 P41221 P53680 P63010 Q00610 Q96CW1 Q9ULV1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARB2 ARR2 ARRB2 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTB CLTC CLTCL2 DVL2 FZD4 HIP9 HYPJ KIAA0034 KIAA0109 KIAA0899 PKCA PKCB PKCG PRKACA PRKCA PRKCB PRKCB1 PRKCG WNT5A	Homo sapiens (human)
TWIK-releated acid-sensitive K+ channel (TASK)	Potassium channel subfamily K member 3 Potassium channel subfamily K member 9	O14649 Q9NPC2	KCNK3 KCNK9 TASK TASK1 TASK3	Homo sapiens (human)
Cargo concentration in the ER	Alpha-1-antitrypsin Amphiregulin CD59 glycoprotein Cathepsin Z Coagulation factor V Coagulation factor VIII Collagen alpha-1(VII) chain Dipeptidyl peptidase 1 Folate receptor alpha Glutamate receptor 1 Golgi SNAP receptor complex member 2 Guanine nucleotide-exchange factor SEC12 Melanoma inhibitory activity protein 2 Multiple coagulation factor deficiency protein 2 Protein ERGIC-53-like Protein ERGIC-53 Protein cornichon homolog 1 Protein cornichon homolog 2 Protein cornichon homolog 3 Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Protransforming growth factor alpha Small COPII coat GTPase SAR1B Syntaxin-5 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Transport and Golgi organization protein 1 homolog VIP36-like protein Vesicle-trafficking protein SEC22b Vesicular integral-membrane protein VIP36	O14653 O75396 O94855 O95406 O95486 O95487 P00451 P01009 P01135 P12259 P13987 P15328 P15514 P42261 P49257 P49755 P53634 P53992 Q02388 Q12907 Q13190 Q15363 Q15436 Q5JRA6 Q6PI25 Q8NI22 Q8TBE1 Q96PC5 Q9H0V9 Q9HAT1 Q9HCU5 Q9UBR2 Q9Y6B6	AAT AREG AREGB C5orf8 CD59 CNIH CNIH1 CNIH2 CNIH3 CNIL COL7A1 CPPI CTAGE5 CTSC CTSZ ERGIC53 ERGL F5 F5F8D F8 F8C FOLR FOLR1 GLUA1 GLUH1 GLUR1 GOSR2 GRIA1 GS27 KIAA0079 KIAA0268 KIAA0755 LMAN1 LMAN1L LMAN2 LMAN2L MCFD2 MEA11 MEA6 MGEA11 MGEA6 MIA2 MIA3 MIC11 MIN1 MIN2 MIN3 MSK21 PI PREB RNP24 SAR1B SARA2 SARB SDGF SDNSF SEC12 SEC22B SEC22L1 SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 STX5 STX5A TANGO TGFA TMED10 TMED2 TMP21 VIPL	Homo sapiens (human)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	O14654 P01344 P05019 P08069 P35568 Q9Y4H2	IBP1 IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Homo sapiens (human)
Retrograde transport at the Trans-Golgi-Network	ADP-ribosylation factor-like protein 1 ADP-ribosylation factor-related protein 1 Alpha-soluble NSF attachment protein Arfaptin-2 Beta-soluble NSF attachment protein Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 GRIP and coiled-coil domain-containing protein 1 GRIP and coiled-coil domain-containing protein 2 Gamma-soluble NSF attachment protein Golgin subfamily A member 1 Golgin subfamily A member 4 Guanine nucleotide exchange factor subunit RIC1 N-alpha-acetyltransferase 30 N-alpha-acetyltransferase 35, NatC auxiliary subunit N-alpha-acetyltransferase 38, NatC auxiliary subunit Perilipin-3 Protein SYS1 homolog RAB6A-GEF complex partner protein 2 Rab9 effector protein with kelch motifs Ras-related protein Rab-43 Ras-related protein Rab-6A Ras-related protein Rab-6B Ras-related protein Rab-9A Ras-related protein Rab-9B Rho-related BTB domain-containing protein 3 Short coiled-coil protein Syntaxin-10 Syntaxin-16 Syntaxin-6 TATA element modulatory factor Trans-Golgi network integral membrane protein 2 USP6 N-terminal-like protein Vacuolar protein sorting-associated protein 51 homolog Vacuolar protein sorting-associated protein 52 homolog Vacuolar protein sorting-associated protein 53 homolog Vacuolar protein sorting-associated protein 54 Vesicle transport through interaction with t-SNAREs homolog 1A Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-fusing ATPase	O14662 O43493 O43752 O60499 O60664 O75379 O94955 P11717 P20340 P20645 P40616 P46459 P51151 P53365 P54920 P82094 P83436 Q13439 Q13795 Q14746 Q147X3 Q15836 Q4ADV7 Q5VIR6 Q5VZE5 Q7Z6M1 Q86YS6 Q8IWJ2 Q8N1B4 Q8N2H4 Q8WTW3 Q92546 Q92738 Q92805 Q96AJ9 Q96CN9 Q96JB2 Q96MW5 Q99747 Q9BRA0 Q9H115 Q9H9E3 Q9NP90 Q9NRW1 Q9P1Q0 Q9UID3 Q9UIL1 Q9UP83 Q9Y2V7	ANG2 ARA160 ARFIP2 ARFRP1 ARL1 ARP1 C11orf2 C11orf3 C14orf35 C20orf169 CIP150 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 EGAP FFR GCC1 GCC2 GOLGA1 GOLGA4 GOLTC1 GTC90 HCC8 IGF2R KIAA0019 KIAA0258 KIAA0336 KIAA0878 KIAA1134 KIAA1381 KIAA1432 LDLB LDLC LSMD1 M6PR M6PRBP1 MAK10 MAK3 MAK31 MPR46 MPRD MPRI NAA30 NAA35 NAA38 NAPA NAPB NAPG NAT12 NSF PFAAP2 PLIN3 POR1 RAB41 RAB43 RAB6 RAB6A RAB6B RAB9 RAB9A RAB9B RAB9L RAB9P40 RABEPK RANBP2L4 RGP1 RHOBTB3 RIC1 SACM2L SCOC SCOCO SEC34 SNAPA SNAPB SNAPG STX10 STX16 STX6 SYB3 SYN10 SYS1 TGN46 TGN51 TGOLN2 TIP47 TMF1 USP6NL VAMP3 VAMP4 VPS51 VPS52 VPS53 VPS54 VTI1A	Homo sapiens (human)
Signaling by EGFR	Amphiregulin Angio-associated migratory cell protein Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 12 Disintegrin and metalloproteinase domain-containing protein 17 Epidermal growth factor receptor Epigen Leucine-rich repeats and immunoglobulin-like domains protein 1 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein FAM83A Protein FAM83B Protein FAM83D Protransforming growth factor alpha	O14672 O14944 O43184 P00533 P01133 P01135 P15514 P35070 P78536 Q13685 Q5T0W9 Q6UW88 Q86UY5 Q96JA1 Q99075 Q9H4H8	AAMP ADAM10 ADAM12 ADAM17 AREG AREGB BTC C20orf129 C6orf143 CSVP DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG FAM83A FAM83B FAM83D HBEGF HEGFL HER1 KUZ LIG1 LRIG1 MADM MLTN SDGF TACE TGFA TSGP	Homo sapiens (human)
EPH-ephrin mediated repulsion of cells	72 kDa type IV collagenase AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Disintegrin and metalloproteinase domain-containing protein 10 Dynamin-1 Ephrin type-A receptor 10 Ephrin type-A receptor 1 Ephrin type-A receptor 2 Ephrin type-A receptor 3 Ephrin type-A receptor 4 Ephrin type-A receptor 5 Ephrin type-A receptor 6 Ephrin type-A receptor 7 Ephrin type-A receptor 8 Ephrin type-B receptor 1 Ephrin type-B receptor 2 Ephrin type-B receptor 3 Ephrin type-B receptor 4 Ephrin type-B receptor 6 Ephrin-A1 Ephrin-A2 Ephrin-A3 Ephrin-A4 Ephrin-A5 Ephrin-B1 Ephrin-B2 Ephrin-B3 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Matrix metalloproteinase-9 Nicastrin Presenilin-1 Presenilin-2 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor TIAM1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O14672 O15197 O43921 O94973 O95782 P06241 P07947 P07948 P08253 P09496 P09497 P14780 P20827 P21709 P29317 P29320 P29322 P29323 P49768 P49810 P52735 P52797 P52798 P52799 P52803 P53675 P53680 P54753 P54756 P54760 P54762 P54764 P63000 P63010 P98172 Q00610 Q05193 Q13009 Q15375 Q15768 Q5JZY3 Q8WW43 Q92542 Q96BI3 Q96CW1 Q9NZ42 Q9UF33 Q9UKW4	AD3 AD4 ADAM10 ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APH1A APH1B BSK CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLG4A CLG4B CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD DNM DNM1 DRT ECK EEK EFL2 EFL3 EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EHK1 EHK2 EHK3 ELK EPH EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 EPHT EPHT1 EPHT2 EPHT3 EPLG1 EPLG2 EPLG3 EPLG4 EPLG5 EPLG6 EPLG7 EPLG8 EPTH3 ERK ETK ETK1 ETK2 FYN HEK HEK11 HEK12 HEK2 HEK3 HEK5 HEK6 HEK7 HEK8 HIP9 HTK HTKL HYPJ JTK8 KIAA0034 KIAA0109 KIAA0253 KIAA0899 KIAA1459 KUZ LERK1 LERK2 LERK3 LERK4 LERK5 LERK6 LERK7 LERK8 LYN MADM MMP2 MMP9 MYK1 NCSTN NET PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RAC1 SEK STM2 TC25 TIAM1 TNFAIP4 TYRO1 TYRO11 TYRO4 TYRO5 TYRO6 VAV2 VAV3 YES YES1	Homo sapiens (human)
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Cathepsin K Collagen alpha-1(IX) chain Collagen alpha-1(XII) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XIV) chain Collagen alpha-1(XIX) chain Collagen alpha-1(XV) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVII) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIII) chain Collagen alpha-1(XXV) chain Collagen alpha-1(XXVI) chain Collagen alpha-2(IX) chain Collagen alpha-3(IX) chain Collagenase 3 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 Disintegrin and metalloproteinase domain-containing protein 9 Furin Interstitial collagenase Macrophage metalloelastase Matrilysin Matrix metalloproteinase-14 Matrix metalloproteinase-15 Matrix metalloproteinase-19 Matrix metalloproteinase-20 Matrix metalloproteinase-9 Neutrophil collagenase Neutrophil elastase Procathepsin L Stromelysin-1 Stromelysin-2 Stromelysin-3 Transmembrane protease serine 6 Trypsin-2	O14672 O60882 P03956 P07339 P07478 P07711 P07858 P08246 P08253 P08254 P09237 P09238 P09958 P14780 P20849 P22894 P24347 P39059 P39060 P39900 P43235 P45452 P50281 P51511 P78536 Q05707 Q07092 Q13443 Q14050 Q14055 Q14993 Q5TAT6 Q86Y22 Q8IU80 Q8IUZ5 Q96A83 Q99542 Q99715 Q9BXS0 Q9UMD9	ADAM10 ADAM17 ADAM9 AGXT2L2 BP180 BPAG2 CLG CLG1 CLG4A CLG4B COL12A1 COL12A1L COL13A1 COL14A1 COL15A1 COL16A1 COL17A1 COL18A1 COL19A1 COL23A1 COL25A1 COL26A1 COL9A1 COL9A2 COL9A3 CPSB CPSD CSVP CTSB CTSD CTSK CTSL CTSL1 CTSO CTSO2 ELA2 ELANE EMID2 EMU2 FUR FURIN HME KIAA0021 KUZ MADM MCMP MDC9 MLTNG MMP1 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP18 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 MPSL1 PACE PCSK3 PHYKPL PRSS2 PUMP1 RASI STMY1 STMY2 STMY3 TACE TMPRSS6 TRY2 TRYP2 UND	Homo sapiens (human)
NOTCH4 Activation and Transmission of Signal to the Nucleus	14-3-3 protein zeta/delta Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 4 Nicastrin Presenilin-1 Presenilin-2 Protein jagged-1	O14672 P49768 P49810 P63104 P78504 Q8WW43 Q92542 Q96BI3 Q99466 Q9NR61 Q9NZ42	AD3 AD4 ADAM10 APH1A APH1B DLL4 INT3 JAG1 JAGL1 KIAA0253 KUZ MADM NCSTN NOTCH4 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 STM2 YWHAZ	Homo sapiens (human)
Uptake of dietary cobalamins into enterocytes	Chymotrypsinogen B2 Chymotrypsinogen B Cobalamin binding intrinsic factor Cubilin Lysosomal cobalamin transport escort protein LMBD1 Lysosomal cobalamin transporter ABCD4 Protein amnionless Serine protease 1 Transcobalamin-1 Trypsin-3	O14678 O60494 P07477 P17538 P20061 P27352 P35030 Q6GPI1 Q9BXJ7 Q9NUN5	ABCD4 AMN C6orf209 CBLIF CTRB CTRB1 CTRB2 CUBN GIF IFCR IFMH LMBRD1 NESI PRSS1 PRSS3 PRSS4 PXMP1L TC1 TCN1 TRP1 TRY1 TRY3 TRY4 TRYP1	Homo sapiens (human)

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