GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **751 - 775** of **2074** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Cyclin-dependent kinase inhibitor 1 Lysine-specific demethylase 5B Myc proto-oncogene protein Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P01106 P05549 P38936 Q92754 Q9UGL1	AP2TF BHLHE39 CAP20 CDKN1 CDKN1A CIP1 JARID1B KDM5B MDA6 MYC PIC1 PLU1 RBBP2H1 SDI1 TFAP2 TFAP2A TFAP2C WAF1	Homo sapiens (human)
Activation of the AP-1 family of transcription factors	Cyclic AMP-dependent transcription factor ATF-2 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Protein c-Fos Transcription factor Jun	P01100 P05412 P15336 P27361 P28482 P45983 P45984 P53779 Q15759 Q16539	ATF2 CREB2 CREBP1 CSBP CSBP1 CSBP2 CSPB1 ERK1 ERK2 FOS G0S7 JNK1 JNK2 JNK3 JNK3A JUN MAPK1 MAPK10 MAPK11 MAPK14 MAPK3 MAPK8 MAPK9 MXI2 PRKM1 PRKM10 PRKM11 PRKM2 PRKM3 PRKM8 PRKM9 SAPK1 SAPK1A SAPK1B SAPK1C SAPK2 SAPK2A SAPK2B	Homo sapiens (human)
TGFBR3 PTM regulation	Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Matrix metalloproteinase-14 Matrix metalloproteinase-16 Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 2 Nicastrin Presenilin-1 Presenilin-2 Transforming growth factor beta receptor type 3	P01033 P16035 P49768 P49810 P50281 P51512 Q03167 Q8WW43 Q92542 Q96BI3 Q9NZ42	AD3 AD4 APH1A APH1B C8orf57 CLGI KIAA0253 MMP14 MMP16 MMPX2 NCSTN PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 STM2 TGFBR3 TIMP TIMP1 TIMP2	Homo sapiens (human)
Terminal pathway of complement	Clusterin Complement C5 Complement component C6 Complement component C7 Complement component C8 alpha chain Complement component C8 beta chain Complement component C8 gamma chain Complement component C9	P01031 P02748 P07357 P07358 P07360 P10643 P10909 P13671	APOJ C5 C6 C7 C8A C8B C8G C9 CLI CLU CPAMD4 KUB1	Homo sapiens (human)
Erythrocytes take up oxygen and release carbon dioxide	Ammonium transporter Rh type A Aquaporin-1 Band 3 anion transport protein Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 4 Hemoglobin subunit alpha Hemoglobin subunit beta	P00915 P00918 P02730 P22748 P29972 P68871 P69905 Q02094	AE1 AQP1 CA1 CA2 CA4 CHIP28 DI EPB3 HBA1 HBA2 HBB RH50 RHAG SLC4A1	Homo sapiens (human)
Erythrocytes take up carbon dioxide and release oxygen	Ammonium transporter Rh type A Aquaporin-1 Band 3 anion transport protein Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 4 Cytochrome b5 reductase 4 Hemoglobin subunit alpha Hemoglobin subunit beta NADH-cytochrome b5 reductase 1 NADH-cytochrome b5 reductase 2 NADH-cytochrome b5 reductase-like	P00915 P00918 P02730 P22748 P29972 P68871 P69905 Q02094 Q6BCY4 Q6IPT4 Q7L1T6 Q9UHQ9	AE1 AQP1 CA1 CA2 CA4 CHIP28 CYB5R1 CYB5R2 CYB5R4 CYB5RL DI EPB3 HBA1 HBA2 HBB NCB5OR NQO3A2 RH50 RHAG SLC4A1	Homo sapiens (human)
Activation of C3 and C5	Complement C2 Complement C3 Complement C4-A Complement C4-B Complement C5 Complement factor B	P00751 P01024 P01031 P06681 P0C0L4 P0C0L5	BF BFD C2 C3 C4A C4B C4B_2 C5 CFB CO4 CPAMD1 CPAMD2 CPAMD3 CPAMD4	Homo sapiens (human)
Defective SERPING1 causes hereditary angioedema	Coagulation factor XII Plasma kallikrein Plasma protease C1 inhibitor	P00748 P03952 P05155	C1IN C1NH F12 KLK3 KLKB1 SERPING1	Homo sapiens (human)
Dissolution of Fibrin Clot	Alpha-2-antiplasmin Annexin A2 Glia-derived nexin Histidine-rich glycoprotein Plasminogen activator inhibitor 1 Plasminogen activator inhibitor 2 Plasminogen Protein S100-A10 Serpin B6 Serpin B8 Tissue-type plasminogen activator Urokinase plasminogen activator surface receptor Urokinase-type plasminogen activator	P00747 P00749 P00750 P04196 P05120 P05121 P07093 P07355 P08697 P35237 P50452 P60903 Q03405	AAP ANX2 ANX2L4 ANX2LG ANXA2 CAL1H CAL1L CLP11 HRG LPC2D MO3 PAI1 PAI2 PI6 PI7 PI8 PLANH1 PLANH2 PLAT PLAU PLAUR PLG PLI PN1 PTI S100A10 SERPINB2 SERPINB6 SERPINB8 SERPINE1 SERPINE2 SERPINF2 UPAR	Homo sapiens (human)
Alternative complement activation	Complement C3 Complement factor B Complement factor D Granzyme M	P00746 P00751 P01024 P51124	BF BFD C3 CFB CFD CPAMD1 DF GZMM MET1 PFD	Homo sapiens (human)
Defective F9 secretion	Coagulation factor IX	P00740	F9	Homo sapiens (human)
Defective gamma-carboxylation of F9	Coagulation factor IX Vitamin K-dependent gamma-carboxylase	P00740 P38435	F9 GC GGCX	Homo sapiens (human)
Defective F9 activation	Coagulation factor IX Coagulation factor XI Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V	P00740 P03951 P07359 P13224 P14770 P40197	F11 F9 GP1BA GP1BB GP5 GP9	Homo sapiens (human)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor IX Coagulation factor VII Coagulation factor X Tissue factor pathway inhibitor Tissue factor	P00740 P00742 P08709 P10646 P13726	F10 F3 F7 F9 LACI TFPI TFPI1	Homo sapiens (human)
Platelet Aggregation (Plug Formation)	Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin Thrombopoietin receptor Thrombopoietin von Willebrand factor	P00734 P04275 P07359 P13224 P14770 P40197 P40225 P40238	F2 F8VWF GP1BA GP1BB GP5 GP9 MGDF MPL THPO TPOR VWF	Homo sapiens (human)
Defective factor XII causes hereditary angioedema	Coagulation factor XII Plasma kallikrein Prothrombin	P00734 P00748 P03952	F12 F2 KLK3 KLKB1	Homo sapiens (human)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P22891 Q14393	AXLLG BGLAP F10 F2 F7 F9 GAS6 PROC PROS PROS1 PROZ	Homo sapiens (human)
Gamma-carboxylation of protein precursors	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent gamma-carboxylase Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P22891 P38435 Q14393	AXLLG BGLAP F10 F2 F7 F9 GAS6 GC GGCX PROC PROS PROS1 PROZ	Homo sapiens (human)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor IX Coagulation factor VII Coagulation factor X Furin Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P09958 P22891 Q14393	AXLLG BGLAP F10 F2 F7 F9 FUR FURIN GAS6 PACE PCSK3 PROC PROS PROS1 PROZ	Homo sapiens (human)
Lactose synthesis	Alpha-lactalbumin Beta-1,4-galactosyltransferase 1 Solute carrier family 2, facilitated glucose transporter member 1	P00709 P11166 P15291	B4GALT1 GGTB2 GLUT1 LALBA LYZL7 SLC2A1	Homo sapiens (human)	G58161NS G74621DY
Uptake and function of diphtheria toxin	CD9 antigen Diphtheria toxin Elongation factor 2 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Proheparin-binding EGF-like growth factor Thioredoxin reductase 1, cytoplasmic	P00588 P07900 P08238 P13639 P21926 Q16881 Q99075	CD9 DTR DTS EEF2 EF2 GRIM12 HBEGF HEGFL HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KDRF MIC3 TSPAN29 TXNRD1	Homo sapiens (human)
Manipulation of host energy metabolism	6 kDa early secretory antigenic target Alpha-enolase Phosphoglycerate kinase 1	P00558 P06733 P9WNK7	ENO1 ENO1L1 MBPB1 MPB1 PGK1 PGKA esaT6 esxA	Homo sapiens (human)
PTK6 promotes HIF1A stabilization	Epidermal growth factor receptor Hypoxia-inducible factor 1-alpha Leucine-rich repeat serine/threonine-protein kinase 2 Proheparin-binding EGF-like growth factor Protein-tyrosine kinase 6 Transmembrane glycoprotein NMB	P00533 Q13882 Q14956 Q16665 Q5S007 Q99075	BHLHE78 BRK DTR DTS EGFR ERBB ERBB1 GPNMB HBEGF HEGFL HER1 HGFIN HIF1A LRRK2 MOP1 NMB PARK8 PASD8 PTK6	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain-containing protein 2 Choriogonadotropin subunit beta 3 Epidermal growth factor receptor Estrogen receptor Glycoprotein hormones alpha chain Mast/stem cell growth factor receptor Kit Protransforming growth factor alpha Receptor tyrosine-protein kinase erbB-2 Transcription factor AP-2 gamma Transcription factor AP-2-alpha Transcription factor AP-2-beta Transcriptional repressor protein YY1 Vascular endothelial growth factor A, long form	P00533 P01135 P01215 P03372 P04626 P05549 P0DN86 P10721 P15692 P25490 Q6PL18 Q92481 Q92754	AP2TF ATAD2 CGA CGB CGB3 CGB5 CGB8 EGFR ERBB ERBB1 ERBB2 ESR ESR1 HER1 HER2 INO80S KIT MLN19 NEU NGL NR3A1 SCFR TFAP2 TFAP2A TFAP2B TFAP2C TGFA VEGF VEGFA YY1	Homo sapiens (human)
PLCG1 events in ERBB2 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Pro-epidermal growth factor Receptor tyrosine-protein kinase erbB-2	P00533 P01133 P04626 P19174	EGF EGFR ERBB ERBB1 ERBB2 HER1 HER2 MLN19 NEU NGL PLC1 PLCG1	Homo sapiens (human)

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