GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **876 - 900** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
Modulation by Mtb of host immune system	6 kDa early secretory antigenic target Beta-2-microglobulin Low molecular weight protein-tyrosine phosphatase A Macrophage mannose receptor 1 Phosphate-binding protein PstS 1 Polyubiquitin-B Polyubiquitin-C Possible transcriptional regulatory protein (Probably Lrp/AsnC-family) Toll-like receptor 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O33321 O60603 P0CG47 P0CG48 P22897 P61769 P62979 P62987 P9WGU1 P9WIA1 P9WNK7	B2M CLEC13D CLEC13DL MRC1 MRC1L1 RPS27A Rv2779c TIL4 TLR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 esaT6 esxA mptpA phoS1 pstS1 ptpA	Homo sapiens (human)
Butyrophilin (BTN) family interactions	Butyrophilin subfamily 1 member A1 Butyrophilin subfamily 2 member A1 Butyrophilin subfamily 2 member A2 Butyrophilin subfamily 3 member A1 Butyrophilin subfamily 3 member A2 Butyrophilin subfamily 3 member A3 Butyrophilin-like protein 2 Butyrophilin-like protein 8 Butyrophilin-like protein 9 CD209 antigen Periplakin Xanthine dehydrogenase/oxidase	O00478 O00481 O60437 P47989 P78410 Q13410 Q6UX41 Q6UXG8 Q7KYR7 Q8WVV5 Q9NNX6 Q9UIR0	BT2.1 BT2.2 BT3.2 BTF1 BTF2 BTF3 BTF4 BTF5 BTN BTN1A1 BTN2A1 BTN2A2 BTN3A1 BTN3A2 BTN3A3 BTNL2 BTNL8 BTNL9 CD209 CLEC4L KIAA0568 PPL XDH XDHA	Homo sapiens (human)
Nicotinamide salvaging	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase ATP-dependent (S)-NAD(P)H-hydrate dehydratase NAD(P)H-hydrate epimerase NAD-capped RNA hydrolase NUDT12 Nicotinamide N-methyltransferase Nicotinamide phosphoribosyltransferase Nicotinate phosphoribosyltransferase Prostacyclin synthase Prostaglandin G/H synthase 2 Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 Renalase Sodium-coupled monocarboxylate transporter 1 Solute carrier family 22 member 13	P35354 P40261 P43490 Q16647 Q2NL67 Q460N5 Q53GL7 Q5VYX0 Q6XQN6 Q8IW45 Q8IXQ6 Q8N3A8 Q8N5Y8 Q8N695 Q8NCW5 Q9BQG2 Q9UKK3 Q9UNU6 Q9Y226	ADPRTL1 AIBP AIT APOA1BP ARTD15 BAL BAL1 BAL2 C10orf59 C15orf30 CARKD COX2 CYP12 CYP8 CYP8A1 CYP8B1 FHIP KIAA0177 KIAA1268 NAMPT NAPRT NAPRT1 NAXD NAXE NNMT NUDT12 OCTL1 ORCTL3 PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL PBEF PBEF1 PTGIS PTGS2 RNLS SLC22A13 SLC5A8 SMCT SMCT1 YJEFN1	Homo sapiens (human)
Regulation of TP53 Activity through Acetylation	Bromodomain and PHD finger-containing protein 3 Bromodomain-containing protein 1 Bromodomain-containing protein 7 Cellular tumor antigen p53 Chromatin modification-related protein MEAF6 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Histone acetyltransferase KAT6A Histone acetyltransferase p300 Histone deacetylase 1 Histone deacetylase 2 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Inhibitor of growth protein 5 Metastasis-associated protein MTA2 Methyl-CpG-binding domain protein 3 Peregrin Protein PML RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Transcriptional repressor p66-alpha Transcriptional repressor p66-beta	O94776 O95696 O95983 P04637 P29590 P31749 P31751 P55201 Q09028 Q09472 Q12873 Q13547 Q14839 Q16576 Q86YP4 Q8WXI9 Q8WYH8 Q92769 Q92794 Q9HAF1 Q9NPI1 Q9ULD4 Q9Y243	AKT1 AKT2 AKT3 BP75 BR140 BRD1 BRD7 BRL BRPF1 BRPF2 BRPF3 C1orf149 CELTIX1 CENP-28 CHD3 CHD4 EAF6 EP300 GATAD2A GATAD2B HDAC1 HDAC2 ING5 KAT6A KIAA1150 KIAA1286 MBD3 MEAF6 MOZ MTA1L1 MTA2 MYL MYST3 P300 P53 PID PKB PKBG PML PP8675 RAC RBAP46 RBAP48 RBBP4 RBBP7 RNF71 RPD3L1 RUNXBP2 TP53 TRIM19 ZNF220	Homo sapiens (human)
Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP)	Organic cation/carnitine transporter 2	O76082	OCTN2 SLC22A5	Homo sapiens (human)
Homologous DNA Pairing and Strand Exchange	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM	O15315 O43502 O43542 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 MRE11 MRE11A NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2 XRCC3	Homo sapiens (human)
RNA Polymerase I Promoter Opening	Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Methyl-CpG-binding domain protein 2 Mitogen-activated protein kinase 3 Nucleolar transcription factor 1	O60814 P04908 P06899 P0C5Y9 P16104 P17480 P20671 P23527 P27361 P33778 P57053 P58876 P62805 P62807 P68431 P84243 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9UBB5	ERK1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 MAPK3 MBD2 PRKM3 TSH2B UBF UBF1 UBTF	Homo sapiens (human)
Defective SLC34A2 causes PALM	Sodium-dependent phosphate transport protein 2B	O95436	SLC34A2	Homo sapiens (human)
Maturation of nucleoprotein	Casein kinase I isoform alpha Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Nucleoprotein Protein arginine N-methyltransferase 1 Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 SRSF protein kinase 1 SRSF protein kinase 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	P0DTC9 P48729 P49840 P49841 P63165 P63279 P78362 Q2NL67 Q460N5 Q53GL7 Q8IXQ6 Q8N3A8 Q8N5Y8 Q96SB4 Q99873 Q9UKK3	ADPRTL1 ARTD15 BAL BAL1 BAL2 C15orf30 CSNK1A1 GSK3A GSK3B HMT2 HRMT1L2 IR1B4 KIAA0177 KIAA1268 N PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL PRMT1 SMT3C SMT3H3 SRPK1 SRPK2 SUMO1 UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Degradation of AXIN	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Axin-1 Axin-2 E3 ubiquitin-protein ligase RNF146 E3 ubiquitin-protein ligase SMURF2 Poly [ADP-ribose] polymerase tankyrase-1 Poly [ADP-ribose] polymerase tankyrase-2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O15169 O43242 O95271 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q13200 Q15008 Q16186 Q99436 Q99460 Q9H2K2 Q9HAU4 Q9NTX7 Q9UNM6 Q9Y2T1	ADRM1 AXIN AXIN1 AXIN2 C7orf76 DSS1 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PARP5A PARP5B PARPL PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RNF146 RPS27A SEM1 SHFDG1 SHFM1 SMURF2 SUG1 SUG2 TANK2 TBP1 TBP7 TIN1 TINF1 TNKL TNKS TNKS1 TNKS2 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
Interleukin-17 signaling	Interleukin-17 receptor A Interleukin-17 receptor B Interleukin-17 receptor C Interleukin-17 receptor E Interleukin-17A Interleukin-17C Interleukin-17F Interleukin-25 ORF8 protein	P0DTC8 Q16552 Q8NAC3 Q8NFR9 Q96F46 Q96PD4 Q9H293 Q9NRM6 Q9P0M4	8 CRL4 CTLA8 EVI27 IL17 IL17A IL17BR IL17C IL17E IL17F IL17R IL17RA IL17RB IL17RC IL17RE IL25	Homo sapiens (human)
TWIK related potassium channel (TREK)	Potassium channel subfamily K member 10 Potassium channel subfamily K member 2 Potassium channel subfamily K member 4	O95069 P57789 Q9NYG8	KCNK10 KCNK2 KCNK4 TRAAK TREK TREK1 TREK2	Homo sapiens (human)
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	Insulin-like growth factor 2 mRNA-binding protein 1 Insulin-like growth factor 2 mRNA-binding protein 2 Insulin-like growth factor 2 mRNA-binding protein 3	O00425 Q9NZI8 Q9Y6M1	CRDBP IGF2BP1 IGF2BP2 IGF2BP3 IMP2 IMP3 KOC1 VICKZ1 VICKZ2 VICKZ3 ZBP1	Homo sapiens (human)
Sensory processing of sound by outer hair cells of the cochlea	55 kDa erythrocyte membrane protein Band 4.1-like protein 1 Band 4.1-like protein 3 Cadherin-23 Calcium and integrin-binding family member 2 Chloride intracellular channel protein 5 Epidermal growth factor receptor kinase substrate 8-like protein 2 Epidermal growth factor receptor kinase substrate 8 Espin-like protein Espin Ezrin Fascin-2 Gelsolin Glutaredoxin domain-containing cysteine-rich protein 1 Glutaredoxin domain-containing cysteine-rich protein 2 Harmonin LHFPL tetraspan subfamily member 5 protein Moesin Myosin-9 Myosin-IIIa Myosin-IIIb Otogelin-like protein Otogelin Pejvakin Peripheral plasma membrane protein CASK Plastin-1 Potassium voltage-gated channel subfamily KQT member 4 Prestin Protocadherin-15 Radixin Rho family-interacting cell polarization regulator 2 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Stereocilin Taperin Transmembrane channel-like protein 1 Transmembrane channel-like protein 2 Transmembrane inner ear expressed protein Twinfilin-1 Twinfilin-2 Unconventional myosin-Ic Unconventional myosin-VIIa Unconventional myosin-XV Whirlin Xin actin-binding repeat-containing protein 2 pre-mRNA splicing regulator USH1G	A4UGR9 A6NFK2 A8MXD5 B1AK53 O00159 O14926 O14936 O75838 P06396 P15311 P26038 P35241 P35579 P56696 P58743 Q00013 Q01082 Q0ZLH3 Q12792 Q12929 Q13402 Q13813 Q14651 Q3ZCN5 Q495M9 Q4KMQ1 Q6IBS0 Q6ZRI0 Q6ZVH7 Q7RTU9 Q8NEV4 Q8NEW7 Q8TAF8 Q8TDI7 Q8TDI8 Q8WXR4 Q96QU1 Q9H251 Q9H4G0 Q9H6S3 Q9NZA1 Q9P202 Q9UKN7 Q9Y2J2 Q9Y4F9 Q9Y6N9	AIE75 C12orf64 C20orf145 C6orf32 C9orf75 CASK CDH23 CIB2 CLIC5 CMYA3 DAL1 DFNB25 DFNB31 DFNB36 DFNB59 DIFF48 DXS552E EMP55 EPB41L1 EPB41L3 EPS8 EPS8L2 EPS8R2 ESPN ESPNL EZR FAM65B FSCN2 GRXCR1 GRXCR2 GSN KCNQ4 KIAA0338 KIAA0386 KIAA0987 KIAA1526 KIAA1774 KIAA1812 KIP2 LHFPL5 LIN2 MPP1 MSN MYH9 MYO15 MYO15A MYO1C MYO3A MYO3B MYO7A NEAS OTGN OTOG OTOGL PCDH15 PJVK PL48 PLS1 PRES PTK9 PTK9L RDX RIPOR2 SANS SLC26A5 SPTA2 SPTAN1 SPTB2 SPTBN1 STRC TMC1 TMC2 TMHS TMIE TPRN TWF1 TWF2 USH1B USH1C USH1F USH1G VIL2 WHRN XIRP2	Homo sapiens (human)
Cyclin D associated events in G1	CDK-activating kinase assembly factor MAT1 Cullin-1 Cyclin-H Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase 7 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 1C Cyclin-dependent kinase inhibitor 2A Cyclin-dependent kinases regulatory subunit 1 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Polyubiquitin-B Polyubiquitin-C Protein-tyrosine kinase 6 Retinoblastoma-associated protein Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F2 Transcription factor E2F3 Transcription factor E2F4 Transcription factor E2F5 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00716 O60674 O96020 P00519 P06400 P07948 P0CG47 P0CG48 P11802 P24385 P24864 P24941 P28749 P30153 P30154 P30279 P30281 P38936 P42771 P42772 P42773 P46527 P49918 P50613 P51946 P51948 P55273 P61024 P62714 P62979 P62987 P63151 P63208 P67775 Q00534 Q01094 Q08999 Q13309 Q13616 Q13882 Q14186 Q14188 Q14209 Q15329 Q16254 Q9Y5P8	ABL ABL1 BCL1 BRK CAK CAK1 CAP20 CAP35 CCND1 CCND2 CCND3 CCNE CCNE1 CCNE2 CCNH CDK2 CDK4 CDK6 CDK7 CDKN1 CDKN1A CDKN1B CDKN1C CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 CDKN7 CIP1 CKS1 CKS1B CUL1 DP1 DP2 E2F1 E2F2 E2F3 E2F4 E2F5 EMC19 FBXL1 JAK2 JTK7 JTK8 KIAA0075 KIP1 KIP2 LYN MAT1 MDA6 MNAT1 MO15 MTS1 MTS2 OCP2 PIC1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R3B PPP2R3L PRAD1 PTK6 RB1 RB2 RBBP3 RBL1 RBL2 RNF66 RPS27A SDI1 SKP1 SKP1A SKP2 STK1 TCEB1L TFDP1 TFDP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAF1 p27	Homo sapiens (human)
PCP/CE pathway	Disheveled-associated activator of morphogenesis 1 Frizzled-1 Frizzled-3 Frizzled-6 Frizzled-7 Profilin-1 Protein Wnt-11 Protein Wnt-4 Protein Wnt-5a Protein Wnt-5b Proto-oncogene Wnt-1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Ras-related C3 botulinum toxin substrate 3 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Transforming protein RhoA Tyrosine-protein kinase RYK Tyrosine-protein kinase transmembrane receptor ROR2 Vang-like protein 2	O14640 O14641 O60353 O75084 O96014 P04628 P07737 P15153 P34925 P41221 P56705 P60763 P61586 P63000 Q01974 Q92997 Q9H1J7 Q9NPG1 Q9ULK5 Q9UP38 Q9Y4D1	ARH12 ARHA DAAM1 DVL1 DVL2 DVL3 FZD1 FZD3 FZD6 FZD7 INT1 JTK5A KIAA0208 KIAA0666 KIAA1215 NTRKR2 PFN1 RAC1 RAC2 RAC3 RHO12 RHOA ROR2 RYK STB1 TC25 VANGL2 WNT1 WNT11 WNT4 WNT5A WNT5B	Homo sapiens (human)
Presynaptic depolarization and calcium channel opening	Dihydropyridine receptor alpha 2 subunit Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent L-type calcium channel subunit beta-4 Voltage-dependent N-type calcium channel subunit alpha-1B Voltage-dependent P/Q-type calcium channel subunit alpha-1A Voltage-dependent R-type calcium channel subunit alpha-1E Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2 Voltage-dependent calcium channel subunit alpha-2/delta-3	O00305 O00555 P54284 Q00975 Q02641 Q08289 Q15878 Q8IZS8 Q9NY47 Q9UBN1 Q9UIU0 Q9Y698	CACH4 CACH5 CACH6 CACN3 CACNA1A CACNA1B CACNA1E CACNA2D1 CACNA2D2 CACNA2D3 CACNB1 CACNB2 CACNB3 CACNB4 CACNG2 CACNG4 CACNL1A4 CACNL1A5 CACNL1A6 CACNLB1 CACNLB2 CACNLB3 CACNLB4 KIAA0558 MYSB	Homo sapiens (human)
SARS-CoV-2 modulates autophagy	Elongation factor Tu, mitochondrial Membrane protein Microtubule-associated proteins 1A/1B light chain 3B ORF3a protein ORF7a protein UV radiation resistance-associated gene protein Vacuolar protein sorting-associated protein 11 homolog Vacuolar protein sorting-associated protein 16 homolog Vacuolar protein sorting-associated protein 18 homolog Vacuolar protein sorting-associated protein 33A Vacuolar protein sorting-associated protein 33B Vacuolar protein sorting-associated protein 41 homolog Vacuolar protein sorting-associated protein 45 Vam6/Vps39-like protein	P0DTC3 P0DTC5 P0DTC7 P49411 P49754 Q96AX1 Q96JC1 Q9GZQ8 Q9H267 Q9H269 Q9H270 Q9NRW7 Q9P253 Q9P2Y5	3a 7a KIAA0770 KIAA1475 M MAP1ALC3 MAP1LC3B RNF108 TLP TUFM UVRAG VAM6 VPS11 VPS16 VPS18 VPS33A VPS33B VPS39 VPS41 VPS45 VPS45A VPS45B	Homo sapiens (human)
Formation of the nephric duct	Bone morphogenetic protein 4 Catenin beta-1 DNA-binding protein inhibitor ID-4 Fibroblast growth factor 2 Histone-lysine N-methyltransferase MECOM Homeobox protein EMX2 Homeobox protein Hox-A6 Homeobox protein Hox-B4 LIM/homeobox protein Lhx1 Nephronectin Paired box protein Pax-2 Paired box protein Pax-8 Placenta-specific gene 8 protein Protein odd-skipped-related 1 Proto-oncogene tyrosine-protein kinase receptor Ret Protocadherin-19 Trans-acting T-cell-specific transcription factor GATA-3 WAP four-disulfide core domain protein 2	P07949 P09038 P12644 P17483 P23771 P31267 P35222 P47928 P48742 Q02962 Q03112 Q04743 Q06710 Q14508 Q6UXI9 Q8TAB3 Q8TAX0 Q9NZF1	BHLHB27 BMP2B BMP4 CDHF12 CDHR16 CTNNB CTNNB1 DVR4 EGFL6L EMX2 EVI1 FGF2 FGFB GATA3 HE4 HOX1B HOX2F HOXA6 HOXB4 ID4 KIAA1313 LHX1 LIM-1 LIM1 MDS1 MECOM NPNT ODD OSR1 PAX2 PAX8 PCDH19 PLAC8 POEM PRDM3 PTC RET WAP5 WFDC2	Homo sapiens (human)
NPAS4 regulates expression of target genes	Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Basic helix-loop-helix ARNT-like protein 1 Brain-derived neurotrophic factor CREB-binding protein Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 E3 ubiquitin-protein ligase Mdm2 Exportin-1 GTP-binding protein GEM IQ motif and SEC7 domain-containing protein 3 Insulin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neuronal PAS domain-containing protein 4 Nicotinamide phosphoribosyltransferase Protein c-Fos Proto-oncogene tyrosine-protein kinase receptor Ret RNA binding protein fox-1 homolog 3 Serine/threonine-protein kinase PLK2 Synaptotagmin-10	A6NFN3 O00327 O14980 P01100 P01308 P07949 P23560 P27361 P27540 P28482 P43490 P55040 Q00535 Q00987 Q15078 Q6XYQ8 Q8IUM7 Q92793 Q9HBZ2 Q9NYY3 Q9UPP2	ARNT ARNT2 ARNTL BDNF BHLHE1 BHLHE2 BHLHE5 BHLHE79 BMAL1 CBP CDHF12 CDHR16 CDK5 CDK5R CDK5R1 CDKN5 CREBBP CRM1 ERK1 ERK2 FOS G0S7 GEM INS IQSEC3 KIAA0307 KIAA1110 KIR MAPK1 MAPK3 MDM2 MOP3 NAMPT NCK5A NPAS4 NXF PASD10 PASD3 PBEF PBEF1 PLK2 PRKM1 PRKM2 PRKM3 PSSALRE PTC RBFOX3 RET SNK SYT10 XPO1	Homo sapiens (human)
Proton-coupled monocarboxylate transport	Basigin Embigin Monocarboxylate transporter 1 Monocarboxylate transporter 2 Monocarboxylate transporter 3 Monocarboxylate transporter 4	O15427 O60669 O95907 P35613 P53985 Q6PCB8	BSG EMB MCT1 MCT2 MCT3 MCT4 SLC16A1 SLC16A3 SLC16A7 SLC16A8	Homo sapiens (human)
Formation of RNA Pol II elongation complex	AF4/FMR2 family member 4 CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 ELL-associated factor 1 ELL-associated factor 2 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Parafibromin Protein AF-9 Protein ENL Protein IWS1 homolog RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase II-associated factor 1 homolog RNA polymerase-associated protein CTR9 homolog RNA polymerase-associated protein LEO1 RNA polymerase-associated protein RTF1 homolog Superkiller complex protein 8 Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription elongation factor SPT6	O00267 O15514 O60563 O60583 O75909 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P42568 P50613 P50750 P51946 P51948 P52298 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q03111 Q08945 Q09161 Q13888 Q13889 Q14241 Q15369 Q15370 Q6P1J9 Q6PD62 Q6ZYL4 Q7KZ85 Q8IXH7 Q8IYF1 Q8N7H5 Q8WVC0 Q8WX92 Q92541 Q92759 Q96CJ1 Q96JC9 Q96ST2 Q9GZS3 Q9H3P2 Q9UHB7 Q9Y5B0 Q9Y5B9	AF5Q31 AF9 AFF4 BTF2 BTF2P44 C19orf17 C1orf28 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CCNK CCNT1 CCNT2 CDC2L4 CDC73 CDK7 CDK9 CDKN7 COBRA1 CPR4 CTDP1 CTR9 EAF1 EAF2 ELL ELOA ELOA2 ELOB ELOC ENL ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HRPT2 IWS1 IWS1L KIAA0155 KIAA0162 KIAA0252 KIAA1182 LEO1 LTG19 MAT1 MCEF MLLT1 MLLT3 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE PAF1 PD2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RDL RNF66 RPB7 RTF1 SH2BP1 SKIC8 SPT4H SPT5 SPT5H SPT6H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H SUPT6H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TRAITS TTDA WDR61 WHSC2 XPB XPBC XPD XPDC YEATS1 YEATS3	Homo sapiens (human)
AKT phosphorylates targets in the cytosol	Bcl2-associated agonist of cell death Caspase-9 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase makorin-1 Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Inhibitor of nuclear factor kappa-B kinase subunit alpha Proline-rich AKT1 substrate 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tuberin	O15111 P31749 P31751 P38936 P46527 P49815 P49840 P49841 P55211 Q00987 Q92934 Q96B36 Q9UHC7 Q9Y243	AKT1 AKT1S1 AKT2 AKT3 BAD BBC6 BCL2L8 CAP20 CASP9 CDKN1 CDKN1A CDKN1B CHUK CIP1 GSK3A GSK3B IKKA KIP1 MCH6 MDA6 MDM2 MKRN1 PIC1 PKB PKBG PRAS40 RAC RNF61 SDI1 TCF16 TSC2 TSC4 WAF1 p27	Homo sapiens (human)
Sunitinib-resistant PDGFR mutants	Platelet-derived growth factor receptor alpha	P16234	PDGFR2 PDGFRA RHEPDGFRA	Homo sapiens (human)
MECP2 regulates neuronal receptors and channels	G protein-regulated inducer of neurite outgrowth 1 Glutamate receptor 2 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Hepatocyte growth factor receptor Histone deacetylase 1 Histone deacetylase 2 Kappa-type opioid receptor Mu-type opioid receptor Paired amphipathic helix protein Sin3a Peptidyl-prolyl cis-trans isomerase FKBP5 Short transient receptor potential channel 3 Solute carrier family 2, facilitated glucose transporter member 3 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 4	P08581 P11169 P18031 P29074 P35372 P41145 P42262 Q12879 Q13224 Q13451 Q13507 Q13547 Q7Z2K8 Q92769 Q96ST3	AIG6 FKBP5 FKBP51 GLUR2 GLUT3 GPRIN1 GRIA2 GRIN2A GRIN2B GluA2 HDAC1 HDAC2 KIAA1893 MET MOR1 NMDAR2A NMDAR2B OPRK OPRK1 OPRM1 PTP1B PTPN1 PTPN4 RPD3L1 SIN3A SLC2A3 TRP3 TRPC3	Homo sapiens (human)

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